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| ASPARAGINE HYDROXYLATION OF THE HIF TRANSACTIVATION DOMAIN: A HYPOXIC SWITCH
LANDO D; PEET DJ; WHELAN DA; GORMAN JJ; WHITELAW ML SCIENCE 295:(5556)858-861 FEB 1 2002 and the citing papers |
Nodes: 199
Authors: 610,
Journals: 112,
Outer References: 6717
Collection span: 2002 - 2004
View: Overview. Sorted by NCR.
Page 1: 1 (513) 2 (53)
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 4 | 513 | 162 2004 CHEMICAL REVIEWS 104(2):939-986 Costas M; Mehn MP; Jensen MP; Que L Dioxygen activation at mononuclear nonheme iron active sites: Enzymes, models, and intermediates | 0 | 5 |
| 2 | 8 | 340 | 163 2004 CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY 39(1):21-68 Hausinger RP Fe(II)/alpha-ketoglutarate-dependent hydroxylases and related enzymes | 0 | 0 |
| 3 | 1 | 278 | 174 2004 FREE RADICAL BIOLOGY AND MEDICINE 36(6):718-744 Kinnula VL; Crapo JD Superoxide dismutases in malignant cells and human tumors | 1 | 3 |
| 4 | 18 | 268 | 145 2004 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 286(4):R608-R623 Hopfl G; Ogunshola O; Gassmann M HIFs and tumors - causes and consequences | 0 | 4 |
| 5 | 11 | 260 | 67 2003 CELLULAR AND MOLECULAR LIFE SCIENCES 60(7):1376-1393 Bracken CP; Whitelaw ML; Peet DJ The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses | 2 | 4 |
| 6 | 2 | 202 | 88 2003 FREE RADICAL BIOLOGY AND MEDICINE 35(2):117-132 Chen K; Thomas SR; Keaney JF Beyond LDL oxidation: ROS in vascular signal transduction | 0 | 9 |
| 7 | 2 | 191 | 41 2002 RESPIRATORY RESEARCH 3(1) Haddad JJ Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology | 0 | 6 |
| 8 | 14 | 190 | 188 2004 NATURE REVIEWS NEUROSCIENCE 5(6):437-448 Sharp FR; Bernaudin M HIf1 and oxygen sensing in the brain | 0 | 0 |
| 9 | 2 | 188 | 28 2002 MASS SPECTROMETRY REVIEWS 21(5):305-348 Rusconi F; Guillonneau F; Praseuth D Contributions of mass spectrometry in the study of nucleic acid-binding proteins and of nucleic acid-protein interactions | 0 | 3 |
| 10 | 24 | 185 | 169 2004 EXPERT OPINION ON THERAPEUTIC PATENTS 14(7):951-966 Zhong H Targeting hypoxia-inducible factor-1 for therapy and prevention | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 1 | 183 | 25 2002 JOURNAL OF MOLECULAR MEDICINE-JMM 80(9):562-575 Acker T; Plate KH A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology | 2 | 9 |
| 12 | 4 | 181 | 75 2003 CURRENT MEDICINAL CHEMISTRY 10(22):2461-2470 Shiao YH The von Hippel-Lindau gene and protein in tumorigenesis and angiogenesis: A potential target for therapeutic designs | 0 | 1 |
| 13 | 1 | 178 | 9 2002 FASEB JOURNAL 16(10) Wenger RH Cellular adaptation to hypoxia: O-2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O-2-regulated gene expression | 0 | 117 |
| 14 | 7 | 174 | 166 2004 DRUG RESISTANCE UPDATES 7(1):25-40 Wouters BG; van den Beucken T; Magagnin MG; Lambin P; Koumenis C Targeting hypoxia tolerance in cancer | 0 | 0 |
| 15 | 5 | 168 | 186 2004 NATURE REVIEWS CANCER 4(5):381-393 Pavlovich CP; Schmidt LS Searching for the hereditary causes of renal-cell carcinoma | 0 | 0 |
| 16 | 5 | 167 | 93 2003 HYPOXIA: THROUGH THE LIFECYCLE 543:89-115 Hopfl G; Ogunshola O; Gassmann M Hypoxia and high altitude - The molecular response | 0 | 1 |
| 17 | 8 | 165 | 146 2004 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 286(6):R977-R988 Fandrey J Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression | 0 | 0 |
| 18 | 4 | 152 | 143 2004 AMERICAN JOURNAL OF NEPHROLOGY 24(1):1-13 Maynard MA; Ohh M von Hippel-Lindau tumor suppressor protein and hypoxia-inducible factor in kidney cancer | 0 | 0 |
| 19 | 7 | 146 | 74 2003 CURRENT MEDICINAL CHEMISTRY 10(12):1005-1019 Hanauske-Abel HM; Popowicz AM The HAG mechanism: A molecular rationale for the therapeutic application of iron chelators in human diseases involving the 2-oxoacid utilizing dioxygenases | 0 | 0 |
| 20 | 5 | 144 | 33 2002 NATURE REVIEWS CANCER 2(9):673-682 Kaelin WG Molecular basis of the VHL hereditary cancer syndrome | 11 | 59 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 21 | 144 | 165 2004 CURRENT PHARMACEUTICAL DESIGN 10(8):821-833 Hewitson KS; McNeill LA; Schofield CJ Modulating the hypoxia-inducible factor signaling pathway: Applications from cardiovascular disease to cancer | 0 | 1 |
| 22 | 5 | 135 | 65 2003 CELL AND TISSUE RESEARCH 314(1):145-155 Acker T; Plate KH Role of hypoxia in tumor angiogenesis - molecular and cellular angiogenic crosstalk | 0 | 0 |
| 23 | 6 | 135 | 151 2004 ARTHRITIS AND RHEUMATISM 50(1):10-23 Distler JHW; Wenger RH; Gassmann M; Kurowska M; Hirth A; Gay S; Distler O Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis | 0 | 1 |
| 24 | 1 | 134 | 70 2003 CLINICAL & EXPERIMENTAL METASTASIS 20(3):237-250 Subarsky P; Hill RP The hypoxic tumour microenvironment and metastatic progression | 0 | 12 |
| 25 | 4 | 131 | 150 2004 ANTIOXIDANTS & REDOX SIGNALING 6(1):155-167 Asikainen TM; White CW Pulmonary antioxidant defenses in the preterm newborn with respiratory distress and bronchopulmonary dysplasia in evolution: Implications for antioxidant therapy | 0 | 1 |
| 26 | 1 | 130 | 59 2003 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1619(2):113-124 Templeton DM; Liu Y Genetic regulation of cell function in response to iron overload or chelation | 0 | 6 |
| 27 | 2 | 128 | 89 2003 FRONTIERS IN BIOSCIENCE 8:D100-D116 Brat DJ; Kaur B; Van Meir EG Genetic modulation of hypoxia induced gene expression and angiogenesis: Relevance to brain tumors | 0 | 5 |
| 28 | 1 | 125 | 12 2002 FREE RADICAL BIOLOGY AND MEDICINE 33(9):1231-1242 Michiels C; Minet E; Mottet D; Raes M Regulation of gene expression by oxygen: NF-kappa B and HIF-1, two extremes | 0 | 11 |
| 29 | 10 | 123 | 167 2004 EXPERIMENTAL AND MOLECULAR MEDICINE 36(1):1-12 Lee JW; Bae SH; Jeong JW; Kim SH; Kim KW Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions | 0 | 0 |
| 30 | 7 | 121 | 81 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(5):781-790 Lando D; Gorman JJ; Whitelaw ML; Peet DJ Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation | 9 | 16 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 1 | 120 | 26 2002 JOURNAL OF MOLECULAR MEDICINE-JMM 80(11):703-714 Kim KR; Moon HE; Kim KW Hypoxia-induced angiogenesis in human hepatocellular carcinoma | 0 | 1 |
| 32 | 3 | 118 | 66 2003 CELLULAR AND MOLECULAR BIOLOGY 49(1):77-87 Karhausen J; Ibla JC; Colgan SP Implications of hypoxia on mucosal barrier function | 1 | 1 |
| 33 | 1 | 117 | 8 2002 EXPERT OPINION ON THERAPEUTIC PATENTS 12(6):777-788 Mabjeesh NJ; Frazier MC; Simons JW; Zhong H Hypoxia-directed cancer therapy | 1 | 1 |
| 34 | 11 | 116 | 129 2003 NATURE REVIEWS DRUG DISCOVERY 2(10):803-811 Giaccia A; Siim BG; Johnson RS HIF-1 as a target for drug development | 2 | 15 |
| 35 | 8 | 115 | 127 2003 NATURE MEDICINE 9(6):677-684 Pugh CW; Ratcliffe PJ Regulation of angiogenesis by hypoxia: role of the HIF system | 10 | 66 |
| 36 | 4 | 114 | 160 2004 CARDIOVASCULAR RESEARCH 62(1):43-52 Martinez-Ruiz A; Lamas S S-nitrosylation: a potential new paradigm in signal transduction | 0 | 1 |
| 37 | 1 | 111 | 27 2002 MASS SPECTROMETRY REVIEWS 21(3):183-216 Gorman JJ; Wallis TP; Pitt JJ Protein disulfide bond determination by mass spectrometry | 0 | 8 |
| 38 | 5 | 111 | 121 2003 MOLECULAR AND CELLULAR BIOLOGY 23(24):9361-9374 Hu CJ; Wang LY; Chodosh LA; Keith B; Simon MC Differential roles of hypoxia-inducible factor 1 alpha (HIF-1 alpha) and HIF-2 alpha in hypoxic gene regulation | 1 | 6 |
| 39 | 2 | 111 | 168 2004 EXPERT OPINION ON INVESTIGATIONAL DRUGS 13(7):829-839 Rebar EJ Development of proangiogenic engineered transcription factors for the treatment of cardiovascular disease | 0 | 0 |
| 40 | 5 | 109 | 51 2003 ANNALS OF MEDICINE 35(6):380-390 Pugh CW Oxygen sensing in cancer | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 22 | 108 | 187 2004 NATURE REVIEWS MOLECULAR CELL BIOLOGY 5(5):343-354 Schofield CJ; Ratcliffe PJ Oxygen sensing by HIF hydroxylases | 0 | 0 |
| 42 | 2 | 107 | 116 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(26):7828-7842 Mehn MP; Fujisawa K; Hegg EL; Que L Oxygen activation by nonheme iron(II) complexes: alpha-keto carboxylate versus carboxylate | 1 | 10 |
| 43 | 11 | 107 | 128 2003 NATURE REVIEWS CANCER 3(10):721-732 Semenza GL Targeting HIF-1 for cancer therapy | 6 | 47 |
| 44 | 2 | 107 | 197 2004 SEMINARS IN CANCER BIOLOGY 14(2):123-130 Mukhopadhyay D; Datta K Multiple regulatory pathways of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in tumors | 0 | 0 |
| 45 | 11 | 104 | 117 2003 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 14(11):2712-2722 Maxwell P HIF-1: An oxygen response system with special relevance to the kidney | 2 | 2 |
| 46 | 4 | 99 | 95 2003 JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 36(1):120-127 Choi KS; Bae MK; Jeong JW; Moon HE; Kim KW Hypoxia-induced angiogenesis during carcinogenesis | 0 | 6 |
| 47 | 17 | 97 | 110 2003 JOURNAL OF CELL SCIENCE 116(15):3041-3049 Masson N; Ratcliffe PJ HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O-2 levels | 2 | 8 |
| 48 | 2 | 97 | 135 2003 REDOX REPORT 8(6):325-340 Land SC Oxygen-sensing pathways and the development of mammalian gas exchange | 0 | 0 |
| 49 | 3 | 91 | 173 2004 FEBS LETTERS 569(1-3):1-6 Kinnula VL; Paakko P; Soini Y Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung | 0 | 0 |
| 50 | 1 | 90 | 52 2003 ANTIOXIDANTS & REDOX SIGNALING 5(1):123-132 Dulak J; Jozkowicz A Regulation of vascular endothelial growth factor synthesis by nitric oxide: Facts and controversies | 0 | 7 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 21 | 90 | 156 2004 BIOLOGICAL CHEMISTRY 385(3-4):223-230 Metzen E; Ratcliffe PJ HIF hydroxylation and cellular oxygen sensing | 0 | 0 |
| 52 | 19 | 89 | 91 2003 GENES & DEVELOPMENT 17(21):2614-2623 Bruick RK Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor | 3 | 12 |
| 53 | 4 | 89 | 149 2004 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 287(1):F1-F6 Sufan RI; Jewett MAS; Ohh M The role of von Hippel-Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma | 0 | 0 |
| 54 | 3 | 88 | 183 2004 JOURNAL OF NEUROSURGERY 100(3):488-497 Jensen RL; Gillespie D; House P; Layfield L; Shelton C Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1 alpha expression | 0 | 0 |
| 55 | 9 | 84 | 155 2004 BIOESSAYS 26(3):262-269 Bardos JI; Athcroft M Hypoxia-inducible factor-1 and oncogenic signalling | 0 | 0 |
| 56 | 2 | 83 | 62 2003 BLOOD 101(3):907-914 Kietzmann T; Samoylenko A; Roth U; Jungermann K Hypoxia-inducible factor-1 and hypoxia response elements mediate the induction of plasminogen activator inhibitor-1 gene expression by insulin in primary rat hepatocytes | 1 | 7 |
| 57 | 2 | 82 | 139 2003 STRAHLENTHERAPIE UND ONKOLOGIE 179(12):801-811 Vordermark D; Brown JM Endogenous markers of tumor hypoxia - Predictors of clinical radiation resistance? | 0 | 2 |
| 58 | 3 | 81 | 73 2003 CURRENT MEDICINAL CHEMISTRY 10(10):845-855 Brune B; Zhou J The role of nitric oxide (NO) in stability regulation of hypoxia inducible factor-1 alpha (HIF-1 alpha) | 1 | 4 |
| 59 | 1 | 80 | 18 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(33):29936-29944 Isaacs JS; Jung YJ; Mimnaugh EG; Martinez A; Cuttitta F; Neckers LM Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway | 19 | 53 |
| 60 | 9 | 79 | 100 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(22):19575-19578 Huang LE; Bunn HF Hypoxia-inducible factor and its biomedical relevance | 9 | 21 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 1 | 78 | 47 2002 TRENDS IN PHARMACOLOGICAL SCIENCES 23(12):576-582 Bikfalvi A; Bicknell R Recent advances in angiogenesis, anti-angiogenesis and vascular targeting | 0 | 19 |
| 62 | 2 | 78 | 138 2003 SEMINARS IN CANCER BIOLOGY 13(1):83-89 Pugh CW; Ratcliffe PJ The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis | 3 | 21 |
| 63 | 6 | 75 | 112 2003 JOURNAL OF CLINICAL INVESTIGATION 111(6):779-783 Safran M; Kaelin WG HIF hydroxylation and the mammalian oxygen-sensing pathway | 1 | 23 |
| 64 | 3 | 74 | 124 2003 MOLECULAR CANCER THERAPEUTICS 2(3):235-243 Welsh SJ; Williams RR; Birmingham A; Newman DJ; Kirkpatrick DL; Powis G The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1 alpha and vascular endothelial growth factor formation | 4 | 12 |
| 65 | 7 | 74 | 184 2004 JOURNAL OF PHARMACOLOGICAL SCIENCES 94(3):221-232 Park JW; Chun YS; Kim NS Hypoxia-inducible factor 1-related diseases and prospective therapeutic tools | 0 | 0 |
| 66 | 2 | 72 | 141 2003 TOR-TARGET OF RAPAMYCIN 279:299-319 Abraham RT MTOR as a positive regulator of tumor cell responses to hypoxia | 0 | 0 |
| 67 | 6 | 71 | 50 2003 ANNALS OF MEDICINE 35(3):183-190 Wiesener MS; Maxwell PH HIF and oxygen sensing; as important to life as the air we breathe? | 1 | 6 |
| 68 | 8 | 71 | 56 2003 BIOCHEMICAL SOCIETY TRANSACTIONS 31:510-515 Hewitson KS; McNeill LA; Elkins JM; Schofield CJ The role of iron and 2-oxoglutarate oxygenases in signalling | 2 | 4 |
| 69 | 2 | 71 | 152 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 316(4):969-977 Haddad JJ Oxygen sensing and oxidant/redox-related pathways | 0 | 0 |
| 70 | 1 | 70 | 36 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(14):9480-9485 Su H; Arakawa-Hoyt J; Kan YW Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model | 1 | 13 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 1 | 70 | 113 2003 JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION 26(9):832-837 Jelkmann W Erythropoietin | 0 | 0 |
| 72 | 4 | 69 | 82 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(5):791-798 Bilton RL; Booker GW The subtle side to hypoxia inducible factor (HIF alpha) regulation | 5 | 11 |
| 73 | 1 | 65 | 176 2004 INTERNATIONAL JOURNAL OF CANCER 111(1):43-50 Swinson DEB; Jones JL; Cox G; Richardson D; Harris AL; O'Byrne KJ Hypoxia-inducible factor-1 alpha in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways | 0 | 0 |
| 74 | 1 | 64 | 5 2002 CANCER RESEARCH 62(17):5089-5095 Welsh SJ; Bellamy WT; Briehl MA; Powis G The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1 alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis | 4 | 15 |
| 75 | 2 | 63 | 72 2003 CLINICAL CANCER RESEARCH 9(8):3150-3157 Palayoor ST; Tofilon PJ; Coleman CN Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1 alpha and HIF-2 alpha in prostate cancer cells | 0 | 2 |
| 76 | 1 | 63 | 106 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(38):35878-35888 Lees MJ; Peet DJ; Whitelaw ML Defining the role for XAP2 in stabilization of the dioxin receptor | 0 | 2 |
| 77 | 10 | 62 | 77 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(6):650-656 Binley K; Kan O; White J; Naylor S Exploiting the hypoxia response | 0 | 1 |
| 78 | 4 | 62 | 144 2004 AMERICAN JOURNAL OF PATHOLOGY 164(6):1875-1882 Michiels C Physiological and pathological responses to hypoxia | 0 | 0 |
| 79 | 1 | 61 | 63 2003 CANCER CELL 3(1):75-88 Mack FA; Rathmell WK; Arsham AM; Gnarra J; Keith B; Simon MC Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth | 6 | 16 |
| 80 | 8 | 60 | 76 2003 CURRENT OPINION IN GENETICS & DEVELOPMENT 13(1):55-60 Kim W; Kaelin WG The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer | 2 | 11 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 1 | 60 | 83 2003 FASEB JOURNAL 17(2) Linden T; Katschinski DM; Eckhardt K; Scheid A; Pagel H; Wenger RH The antimycotic ciclopirox olamine induces HIF-1 alpha stability, VEGF expression, and angiogenesis | 0 | 0 |
| 82 | 1 | 59 | 23 2002 JOURNAL OF EXPERIMENTAL BIOLOGY 205(23):3579-3586 Bickler PE; Donohoe PH Adaptive responses of vertebrate neurons to hypoxia | 0 | 7 |
| 83 | 2 | 59 | 45 2002 TRENDS IN CARDIOVASCULAR MEDICINE 12(8):362-367 Vincent KA; Feron O; Kelly RA Harnessing the response to tissue hypoxia - HIF-1 alpha and therapeutic angiogenesis | 1 | 3 |
| 84 | 6 | 59 | 53 2003 ANTIOXIDANTS & REDOX SIGNALING 5(4):467-473 Goda N; Dozier SJ; Johnson RS HIF-1 in cell cycle regulation, apoptosis, and tumor progression | 0 | 2 |
| 85 | 1 | 59 | 102 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(25):22316-22324 Del Toro R; Levitsky KL; Lopez-Barneo J; Chiara MD Induction of T-type calcium channel gene expression by chronic hypoxia | 0 | 5 |
| 86 | 6 | 59 | 123 2003 MOLECULAR BIOLOGY OF THE CELL 14(8):3470-3481 Metzen E; Zhou J; Jelkmann W; Fandrey J; Brune B Nitric oxide impairs normoxic degradation of HIF-1 alpha by inhibition of prolyl hydroxylases | 6 | 13 |
| 87 | 2 | 58 | 49 2003 ANNALS OF INTERNAL MEDICINE 138(8):659-668 Brat DJ; Mapstone TB Malignant glioma physiology: Cellular response to hypoxia and its role in tumor progression | 0 | 3 |
| 88 | 1 | 58 | 105 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(35):33384-33391 Kodama T; Shimizu N; Yoshikawa N; Makino Y; Ouchida R; Okamoto K; Hisada T; Nakamura H; Morimoto C; Tanaka H Role of the glucocorticoid receptor for regulation of hypoxia-dependent gene expression | 0 | 0 |
| 89 | 2 | 58 | 195 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(28):10440-10445 Kong TQ; Eltzschig HK; Karhausen J; Colgan SP; Shelley CS Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction Of beta 2 integrin gene expression | 0 | 0 |
| 90 | 1 | 57 | 29 2002 METHODS 28(2):259-266 Tang Y; Schmitt-Ott K; Qian KP; Kagiyama S; Phillips MI Vigilant vectors: adeno-associated virus with a biosensor to switch on amplified therapeutic genes in specific tissues in life-threatening diseases | 1 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 1 | 57 | 30 2002 MOLECULAR AND CELLULAR BIOLOGY 22(19):6842-6853 Lavista-Llanos S; Centanin L; Irisarri M; Russo DM; Gleadle JM; Bocca SN; Muzzopappa M; Ratcliffe PJ; Wappner P Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar | 11 | 23 |
| 92 | 4 | 57 | 133 2003 PLACENTA 24(10):941-950 Schaffer L; Scheid A; Spielmann P; Breymann C; Zimmermann R; Meuli M; Gassmann M; Marti HH; Wenger RH Oxygen-regulated expression of TGF-beta 3, a growth factor involved in trophoblast differentiation | 1 | 2 |
| 93 | 8 | 56 | 126 2003 MOLECULES AND CELLS 16(1):1-12 Freeman RS; Hasbani DM; Lipscomb EA; Straub JA; Xie L SM-20, EGL-9, and the EGLN family of hypoxia-inducible factor prolyl hydroxylases | 0 | 1 |
| 94 | 4 | 56 | 137 2003 SEIKAGAKU 75(7):577-587 Tomita T; Saito MI Recent progress in biochemical studies of hemoprotein | 0 | 0 |
| 95 | 5 | 55 | 98 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(16):14013-14019 Sang NL; Stiehl DP; Bohensky J; Leshchinsky I; Srinivas V; Caro J MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300 | 6 | 20 |
| 96 | 1 | 55 | 132 2003 PLACENTA 24(2-3):199-208 Rajakumar A; Doty K; Daftary A; Harger G; Conrad KP Impaired oxygen-dependent reduction of HIF-1 alpha and -2 alpha proteins in pre-eclamptic placentae | 4 | 7 |
| 97 | 2 | 55 | 142 2003 TRENDS IN ENDOCRINOLOGY AND METABOLISM 14(10):453-459 Baysal BE On the association of succinate dehydrogenase mutations with hereditary paraganglioma | 0 | 1 |
| 98 | 2 | 54 | 15 2002 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 54(5):1537-1549 Janssen HLK; Haustermans KMG; Sprong D; Blommestijn G; Hofland I; Hoebers FJ; Blijweert E; Raleigh JA; Semenza GL; Varia MA; Balm AJ; van Velthuysen MLF; Delaere P; Sciot R; Begg AC HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors | 3 | 8 |
| 99 | 3 | 54 | 148 2004 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 286(2):F338-F348 Turcotte S; Desrosiers RR; Beliveau R Hypoxia upregulates von Hippel-Lindau tumor-suppressor protein through RhoA-dependent activity in renal cell carcinoma | 0 | 0 |
| 100 | 5 | 53 | 22 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(44):41750-41755 Huang LE; Pete EA; Schau M; Milligan J; Gu J Leu-574 of HIF-1 alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway | 4 | 7 |
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