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ASPARAGINE HYDROXYLATION OF THE HIF TRANSACTIVATION DOMAIN: A HYPOXIC SWITCH
LANDO D; PEET DJ; WHELAN DA; GORMAN JJ; WHITELAW ML SCIENCE 295:(5556)858-861 FEB 1 2002 and the citing papers |
Nodes: 199
Authors: 610,
Journals: 112,
Outer References: 6717
Collection span: 2002 - 2004
View: Overview. Sorted by journal name.
Page 1: 1 (AMERICAN JOURNAL OF NEPHROLOGY) 2 (JOURNAL OF BIOLOGICAL CHEMISTRY)
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
---|---|---|---|---|---|
1 | 4 | 152 | 143 2004 AMERICAN JOURNAL OF NEPHROLOGY 24(1):1-13 Maynard MA; Ohh M von Hippel-Lindau tumor suppressor protein and hypoxia-inducible factor in kidney cancer | 0 | 0 |
2 | 4 | 62 | 144 2004 AMERICAN JOURNAL OF PATHOLOGY 164(6):1875-1882 Michiels C Physiological and pathological responses to hypoxia | 0 | 0 |
3 | 1 | 44 | 48 2003 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 284(2):C439-C446 Zhou J; Fandrey J; Schumann J; Tiegs G; Brune B NO and TNF-alpha released from activated macrophages stabilize HIF-1 alpha in resting tubular LLC-PK1 cells | 0 | 7 |
4 | 1 | 26 | 1 2002 AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 283(5):L918-L921 Schumacker PT Hypoxia, anoxia, and O-2 sensing: the search continues | 0 | 5 |
5 | 18 | 268 | 145 2004 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 286(4):R608-R623 Hopfl G; Ogunshola O; Gassmann M HIFs and tumors - causes and consequences | 0 | 4 |
6 | 8 | 165 | 146 2004 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 286(6):R977-R988 Fandrey J Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression | 0 | 0 |
7 | 2 | 38 | 147 2004 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 287(3):R600-R607 Ma Y; Freitag P; Zhou J; Brune B; Frede S; Fandrey J Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1 | 0 | 0 |
8 | 3 | 54 | 148 2004 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 286(2):F338-F348 Turcotte S; Desrosiers RR; Beliveau R Hypoxia upregulates von Hippel-Lindau tumor-suppressor protein through RhoA-dependent activity in renal cell carcinoma | 0 | 0 |
9 | 4 | 89 | 149 2004 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 287(1):F1-F6 Sufan RI; Jewett MAS; Ohh M The role of von Hippel-Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma | 0 | 0 |
10 | 2 | 58 | 49 2003 ANNALS OF INTERNAL MEDICINE 138(8):659-668 Brat DJ; Mapstone TB Malignant glioma physiology: Cellular response to hypoxia and its role in tumor progression | 0 | 3 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
11 | 6 | 71 | 50 2003 ANNALS OF MEDICINE 35(3):183-190 Wiesener MS; Maxwell PH HIF and oxygen sensing; as important to life as the air we breathe? | 1 | 6 |
12 | 5 | 109 | 51 2003 ANNALS OF MEDICINE 35(6):380-390 Pugh CW Oxygen sensing in cancer | 0 | 0 |
13 | 1 | 90 | 52 2003 ANTIOXIDANTS & REDOX SIGNALING 5(1):123-132 Dulak J; Jozkowicz A Regulation of vascular endothelial growth factor synthesis by nitric oxide: Facts and controversies | 0 | 7 |
14 | 6 | 59 | 53 2003 ANTIOXIDANTS & REDOX SIGNALING 5(4):467-473 Goda N; Dozier SJ; Johnson RS HIF-1 in cell cycle regulation, apoptosis, and tumor progression | 0 | 2 |
15 | 4 | 131 | 150 2004 ANTIOXIDANTS & REDOX SIGNALING 6(1):155-167 Asikainen TM; White CW Pulmonary antioxidant defenses in the preterm newborn with respiratory distress and bronchopulmonary dysplasia in evolution: Implications for antioxidant therapy | 0 | 1 |
16 | 6 | 135 | 151 2004 ARTHRITIS AND RHEUMATISM 50(1):10-23 Distler JHW; Wenger RH; Gassmann M; Kurowska M; Hirth A; Gay S; Distler O Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis | 0 | 1 |
17 | 4 | 23 | 54 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 303(3):947-953 Cioffi CL; Liu XQ; Kosinski PA; Garay M; Bowen BR Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells | 8 | 16 |
18 | 3 | 33 | 55 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 312(3):571-577 Hanze J; Eul BG; Savai R; Krick S; Goyal P; Grimminger F; Seeger W; Rose F RNA interference for HIF-1 alpha inhibits its downstream signalling and affects cellular proliferation | 2 | 3 |
19 | 2 | 71 | 152 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 316(4):969-977 Haddad JJ Oxygen sensing and oxidant/redox-related pathways | 0 | 0 |
20 | 3 | 38 | 153 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 317(1):84-91 Takahashi R; Kobayashi C; Kondo Y; Nakatani Y; Kudo I; Kunimoto M; Imura N; Hara S Subcellular localization and regulation of hypoxia-inducible factor-2 alpha in vascular endothelial cells | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
21 | 4 | 31 | 2 2002 BIOCHEMICAL JOURNAL 367:571-575 McNeill LA; Hewitson KS; Claridge TD; Seibel JF; Horsfall LE; Schofield CJ Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803 | 17 | 22 |
22 | 8 | 71 | 56 2003 BIOCHEMICAL SOCIETY TRANSACTIONS 31:510-515 Hewitson KS; McNeill LA; Elkins JM; Schofield CJ The role of iron and 2-oxoglutarate oxygenases in signalling | 2 | 4 |
23 | 5 | 44 | 57 2003 BIOCHEMISTRY 42(33):9937-9945 Dial R; Sun ZYJ; Freedman SJ Three conformational states of the p300 CH1 domain define its functional properties | 0 | 1 |
24 | 1 | 45 | 58 2003 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1626(1-3):10-18 Graven KK; Bellur D; Klahn BD; Lowrey SL; Amberger E HIF-2 alpha regulates glyceraldehyde-3-phosphate dehydrogenase expression in endothelial cells | 1 | 4 |
25 | 1 | 130 | 59 2003 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1619(2):113-124 Templeton DM; Liu Y Genetic regulation of cell function in response to iron overload or chelation | 0 | 6 |
26 | 1 | 21 | 154 2004 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1691(1):17-22 Daly EB; Wind T; Jiang XM; Sun L; Hogg PJ Secretion of phosphoglycerate kinase from tumour cells is controlled by oxygen-sensing hydroxylases | 0 | 0 |
27 | 3 | 31 | 60 2003 BIOESSAYS 25(5):515-519 Hochachka PW; Rupert JL Fine tuning the HIF-1 'global' O-2 sensor for hypobaric hypoxia in Andean high-altitude natives | 0 | 1 |
28 | 9 | 84 | 155 2004 BIOESSAYS 26(3):262-269 Bardos JI; Athcroft M Hypoxia-inducible factor-1 and oncogenic signalling | 0 | 0 |
29 | 21 | 90 | 156 2004 BIOLOGICAL CHEMISTRY 385(3-4):223-230 Metzen E; Ratcliffe PJ HIF hydroxylation and cellular oxygen sensing | 0 | 0 |
30 | 2 | 37 | 157 2004 BIOLOGICAL CHEMISTRY 385(3-4):231-237 Berchner-Pfannschmidt U; Wotzlaw C; Merten E; Acker H; Fandrey J Visualization of the three-dimensional organization of hypoxia-inducible factor-1 alpha and interacting cofactors in subnuclear structures | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
31 | 4 | 29 | 61 2003 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(16):2677-2680 Mole DR; Schlemminger I; McNeill LA; Hewitson KS; Pugh CW; Ratcliffe PJ; Schofield CJ 2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase | 3 | 3 |
32 | 2 | 83 | 62 2003 BLOOD 101(3):907-914 Kietzmann T; Samoylenko A; Roth U; Jungermann K Hypoxia-inducible factor-1 and hypoxia response elements mediate the induction of plasminogen activator inhibitor-1 gene expression by insulin in primary rat hepatocytes | 1 | 7 |
33 | 1 | 49 | 3 2002 BLOOD PURIFICATION 20(5):445-450 Ratcliffe PJ From erythropoietin to oxygen: Hypoxia-inducible factor hydroxylases and the hypoxia signal pathway | 3 | 6 |
34 | 1 | 26 | 4 2002 BULLETIN DU CANCER 89(3):257-260 L'Allemain G The hypoxia-inducible factor HIF as a new target in cancer research | 0 | 2 |
35 | 1 | 61 | 63 2003 CANCER CELL 3(1):75-88 Mack FA; Rathmell WK; Arsham AM; Gnarra J; Keith B; Simon MC Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth | 6 | 16 |
36 | 1 | 64 | 5 2002 CANCER RESEARCH 62(17):5089-5095 Welsh SJ; Bellamy WT; Briehl MA; Powis G The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1 alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis | 4 | 15 |
37 | 1 | 34 | 158 2004 CANCER RESEARCH 64(2):456-462 Datta K; Li JP; Bhattacharya R; Gasparian L; Wang EF; Mukhopadhyay D Protein kinase C zeta transactivates hypoxia-inducible factor alpha by promoting its association with p300 in renal cancer | 1 | 2 |
38 | 1 | 51 | 159 2004 CANCER RESEARCH 64(5):1765-1772 Mizukami Y; Li JN; Zhang XB; Zimmer MA; Iliopoulos O; Chung DC Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer | 0 | 0 |
39 | 2 | 50 | 64 2003 CANCER SCIENCE 94(12):1021-1028 Kizaka-Kondoh S; Inoue M; Harada H; Hiraoka M Tumor hypoxia: A target for selective cancer therapy | 0 | 2 |
40 | 4 | 114 | 160 2004 CARDIOVASCULAR RESEARCH 62(1):43-52 Martinez-Ruiz A; Lamas S S-nitrosylation: a potential new paradigm in signal transduction | 0 | 1 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
41 | 2 | 49 | 6 2002 CELL 111(5):709-720 Jeong JW; Bae MK; Ahn MY; Kim SH; Sohn TK; Bae MH; Yoo MA; Song EJ; Lee KJ; Kim KW Regulation and destabilization of HIF-1 alpha by ARD1-mediated acetylation | 23 | 43 |
42 | 5 | 135 | 65 2003 CELL AND TISSUE RESEARCH 314(1):145-155 Acker T; Plate KH Role of hypoxia in tumor angiogenesis - molecular and cellular angiogenic crosstalk | 0 | 0 |
43 | 8 | 40 | 161 2004 CELL CYCLE 3(2):156-159 Maxwell PH HIF-1's relationship to oxygen - Simple yet sophisticated | 0 | 1 |
44 | 3 | 118 | 66 2003 CELLULAR AND MOLECULAR BIOLOGY 49(1):77-87 Karhausen J; Ibla JC; Colgan SP Implications of hypoxia on mucosal barrier function | 1 | 1 |
45 | 11 | 260 | 67 2003 CELLULAR AND MOLECULAR LIFE SCIENCES 60(7):1376-1393 Bracken CP; Whitelaw ML; Peet DJ The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses | 2 | 4 |
46 | 4 | 513 | 162 2004 CHEMICAL REVIEWS 104(2):939-986 Costas M; Mehn MP; Jensen MP; Que L Dioxygen activation at mononuclear nonheme iron active sites: Enzymes, models, and intermediates | 0 | 5 |
47 | 1 | 32 | 68 2003 CHEMORECEPTION: FROM CELLULAR SIGNALLING TO FUNCTIONAL PLASTICITY 536:65-73 Ortega-Saenz P; Garcia-Fernandez M; Pardal R; Alvarez E; Lopez-Barneo J Studies on glomus cell sensitivity to hypoxia in carotid body slices | 0 | 1 |
48 | 2 | 40 | 69 2003 CIRCULATION RESEARCH 93(11):1074-1081 Kelly BD; Hackett SF; Hirota K; Oshima Y; Cai ZQ; Berg-Dixon S; Rowan A; Yan ZJ; Campochiaro PA; Semenza GL Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1 | 1 | 3 |
49 | 1 | 134 | 70 2003 CLINICAL & EXPERIMENTAL METASTASIS 20(3):237-250 Subarsky P; Hill RP The hypoxic tumour microenvironment and metastatic progression | 0 | 12 |
50 | 1 | 43 | 71 2003 CLINICAL CANCER RESEARCH 9(1):433-440 Park JH; Kim TY; Jong HS; Kim TY; Chun YS; Park JW; Lee CT; Jung HC; Kim NK; Bang YJ Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1 alpha in gastric cancer cells | 1 | 2 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
51 | 2 | 63 | 72 2003 CLINICAL CANCER RESEARCH 9(8):3150-3157 Palayoor ST; Tofilon PJ; Coleman CN Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1 alpha and HIF-2 alpha in prostate cancer cells | 0 | 2 |
52 | 8 | 340 | 163 2004 CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY 39(1):21-68 Hausinger RP Fe(II)/alpha-ketoglutarate-dependent hydroxylases and related enzymes | 0 | 0 |
53 | 3 | 81 | 73 2003 CURRENT MEDICINAL CHEMISTRY 10(10):845-855 Brune B; Zhou J The role of nitric oxide (NO) in stability regulation of hypoxia inducible factor-1 alpha (HIF-1 alpha) | 1 | 4 |
54 | 7 | 146 | 74 2003 CURRENT MEDICINAL CHEMISTRY 10(12):1005-1019 Hanauske-Abel HM; Popowicz AM The HAG mechanism: A molecular rationale for the therapeutic application of iron chelators in human diseases involving the 2-oxoacid utilizing dioxygenases | 0 | 0 |
55 | 4 | 181 | 75 2003 CURRENT MEDICINAL CHEMISTRY 10(22):2461-2470 Shiao YH The von Hippel-Lindau gene and protein in tumorigenesis and angiogenesis: A potential target for therapeutic designs | 0 | 1 |
56 | 8 | 60 | 76 2003 CURRENT OPINION IN GENETICS & DEVELOPMENT 13(1):55-60 Kim W; Kaelin WG The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer | 2 | 11 |
57 | 8 | 45 | 164 2004 CURRENT OPINION IN GENETICS & DEVELOPMENT 14(1):81-85 Poellinger L; Johnson RS HIF-1 and hypoxic response: the plot thickens | 0 | 0 |
58 | 10 | 62 | 77 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(6):650-656 Binley K; Kan O; White J; Naylor S Exploiting the hypoxia response | 0 | 1 |
59 | 1 | 50 | 78 2003 CURRENT OPINION IN NEUROBIOLOGY 13(4):493-499 Lopez-Barneo J Oxygen and glucose sensing by carotid body glomus cells | 0 | 4 |
60 | 21 | 144 | 165 2004 CURRENT PHARMACEUTICAL DESIGN 10(8):821-833 Hewitson KS; McNeill LA; Schofield CJ Modulating the hypoxia-inducible factor signaling pathway: Applications from cardiovascular disease to cancer | 0 | 1 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
61 | 7 | 174 | 166 2004 DRUG RESISTANCE UPDATES 7(1):25-40 Wouters BG; van den Beucken T; Magagnin MG; Lambin P; Koumenis C Targeting hypoxia tolerance in cancer | 0 | 0 |
62 | 1 | 52 | 79 2003 EMBO JOURNAL 22(8):1857-1867 Li ZB; Wang DK; Na X; Schoen SR; Messing EM; Wu G The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1 alpha transcriptional activity | 3 | 5 |
63 | 7 | 49 | 80 2003 EMBO JOURNAL 22(16):4082-4090 Berra E; Benizri E; Ginouves A; Volmat V; Roux D; Pouyssegur J HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1 alpha in normoxia | 10 | 25 |
64 | 7 | 121 | 81 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(5):781-790 Lando D; Gorman JJ; Whitelaw ML; Peet DJ Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation | 9 | 16 |
65 | 4 | 69 | 82 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(5):791-798 Bilton RL; Booker GW The subtle side to hypoxia inducible factor (HIF alpha) regulation | 5 | 11 |
66 | 10 | 123 | 167 2004 EXPERIMENTAL AND MOLECULAR MEDICINE 36(1):1-12 Lee JW; Bae SH; Jeong JW; Kim SH; Kim KW Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions | 0 | 0 |
67 | 1 | 32 | 7 2002 EXPERIMENTAL GERONTOLOGY 37(8-9):1077-1088 Trubiani O; Di Giulio C; Tripodi D; Bianchi G; Paganelli R; Di Primio R Thymic sensitivity to hypoxic condition in young and old rats. Age-dependent expression of NF-kappa B | 0 | 2 |
68 | 2 | 111 | 168 2004 EXPERT OPINION ON INVESTIGATIONAL DRUGS 13(7):829-839 Rebar EJ Development of proangiogenic engineered transcription factors for the treatment of cardiovascular disease | 0 | 0 |
69 | 1 | 117 | 8 2002 EXPERT OPINION ON THERAPEUTIC PATENTS 12(6):777-788 Mabjeesh NJ; Frazier MC; Simons JW; Zhong H Hypoxia-directed cancer therapy | 1 | 1 |
70 | 24 | 185 | 169 2004 EXPERT OPINION ON THERAPEUTIC PATENTS 14(7):951-966 Zhong H Targeting hypoxia-inducible factor-1 for therapy and prevention | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
71 | 1 | 178 | 9 2002 FASEB JOURNAL 16(10) Wenger RH Cellular adaptation to hypoxia: O-2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O-2-regulated gene expression | 0 | 117 |
72 | 2 | 33 | 10 2002 FASEB JOURNAL 16(13) La Ferla K; Reimann C; Jelkmann W; Hellwig-Burgel T Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kappa B | 0 | 0 |
73 | 1 | 60 | 83 2003 FASEB JOURNAL 17(2) Linden T; Katschinski DM; Eckhardt K; Scheid A; Pagel H; Wenger RH The antimycotic ciclopirox olamine induces HIF-1 alpha stability, VEGF expression, and angiogenesis | 0 | 0 |
74 | 3 | 45 | 84 2003 FASEB JOURNAL 17(6) Warnecke C; Griethe W; Weidemann A; Jurgensen JS; Willam C; Bachmann S; Ivashchenko Y; Wagner I; Frei U; Wiesener M; Eckardt KU Activation of the hypoxia-inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors | 0 | 0 |
75 | 1 | 36 | 85 2003 FASEB JOURNAL 17(15) Moon EJ; Jeong CH; Jeong JW; Kim KR; Yu DY; Murakami S; Kim CW; Kim KW Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1 alpha | 0 | 0 |
76 | 11 | 43 | 170 2004 FASEB JOURNAL 18(6) Kageyama Y; Koshiji M; To KKW; Tian YM; Ratcliffe PJ; Huang LE Leu-574 of human HIF-1a is a molecular determinant of prolyl hydroxylation | 0 | 0 |
77 | 5 | 44 | 171 2004 FASEB JOURNAL 18(10) Warnecke C; Zaborowska Z; Kurreck J; Erdmann VA; Frei U; Wiesener M; Eckardt KU Differentiating the functional role of hypoxia-inducible factor (HIF)-1 alpha and HIF-2 alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2 alpha target gene in Hep3B and Kelly cells | 0 | 0 |
78 | 2 | 48 | 172 2004 FASEB JOURNAL 18(10) Jurgensen JS; Rosenberger C; Wiesener MS; Warnecke C; Horstrup JH; Grafe M; Philipp S; Griethe W; Maxwell PH; Frei U; Bachmann S; Willenbrock R; Eckardt KU Persistent induction of HIF-1 alpha and -2 alpha in cardiomyocytes and stromal cells of ischemic myocardium | 0 | 0 |
79 | 1 | 22 | 11 2002 FEBS LETTERS 530(1-3):186-190 Saarikoski ST; Rivera SP; Hankinson O Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia | 1 | 4 |
80 | 2 | 28 | 86 2003 FEBS LETTERS 549(1-3):105-109 Yasinska IM; Sumbayev VV S-nitrosation of Cys-800 of HIF-1 alpha protein activates its interaction with p300 and stimulates its transcriptional activity | 1 | 2 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
81 | 1 | 30 | 87 2003 FEBS LETTERS 554(3):264-270 Minchenko O; Opentanova I; Caro J Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo | 0 | 2 |
82 | 3 | 91 | 173 2004 FEBS LETTERS 569(1-3):1-6 Kinnula VL; Paakko P; Soini Y Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung | 0 | 0 |
83 | 1 | 125 | 12 2002 FREE RADICAL BIOLOGY AND MEDICINE 33(9):1231-1242 Michiels C; Minet E; Mottet D; Raes M Regulation of gene expression by oxygen: NF-kappa B and HIF-1, two extremes | 0 | 11 |
84 | 2 | 202 | 88 2003 FREE RADICAL BIOLOGY AND MEDICINE 35(2):117-132 Chen K; Thomas SR; Keaney JF Beyond LDL oxidation: ROS in vascular signal transduction | 0 | 9 |
85 | 1 | 278 | 174 2004 FREE RADICAL BIOLOGY AND MEDICINE 36(6):718-744 Kinnula VL; Crapo JD Superoxide dismutases in malignant cells and human tumors | 1 | 3 |
86 | 1 | 52 | 175 2004 FREE RADICAL BIOLOGY AND MEDICINE 36(10):1279-1288 Goyal P; Weissmann N; Grimminger F; Hegel C; Bader L; Rose F; Fink L; Ghofrani HA; Schermuly RT; Schmidt HHHW; Seeger W; Hanze J Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxiainducible factor 1 via increase in reactive oxygen species | 0 | 0 |
87 | 2 | 128 | 89 2003 FRONTIERS IN BIOSCIENCE 8:D100-D116 Brat DJ; Kaur B; Van Meir EG Genetic modulation of hypoxia induced gene expression and angiogenesis: Relevance to brain tumors | 0 | 5 |
88 | 3 | 43 | 90 2003 GENE THERAPY 10(25):2081-2089 Sun X; Kanwar JR; Leung E; Vale M; Krissansen GW Regression of solid tumors by engineered overexpression of von Hippel-Lindau tumor suppressor protein and antisense hypoxia-inducible factor-1 alpha | 1 | 2 |
89 | 3 | 41 | 13 2002 GENES & DEVELOPMENT 16(12):1441-1445 Kaelin WG How oxygen makes its presence felt | 8 | 31 |
90 | 19 | 89 | 91 2003 GENES & DEVELOPMENT 17(21):2614-2623 Bruick RK Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor | 3 | 12 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
91 | 1 | 39 | 92 2003 HISTOCHEMISTRY AND CELL BIOLOGY 120(5):343-352 Baby SM; Roy A; Mokashi AM; Lahiri S Effects of hypoxia and intracellular iron chelation on hypoxia-inducible factor-1 alpha and -1 beta in the rat carotid body and glomus cells | 1 | 3 |
92 | 5 | 167 | 93 2003 HYPOXIA: THROUGH THE LIFECYCLE 543:89-115 Hopfl G; Ogunshola O; Gassmann M Hypoxia and high altitude - The molecular response | 0 | 1 |
93 | 1 | 65 | 176 2004 INTERNATIONAL JOURNAL OF CANCER 111(1):43-50 Swinson DEB; Jones JL; Cox G; Richardson D; Harris AL; O'Byrne KJ Hypoxia-inducible factor-1 alpha in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways | 0 | 0 |
94 | 1 | 4 | 14 2002 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 54(5):1299-1301 Brown JM; Le QT Tumor hypoxia is important in radiotherapy, but how should we measure it? | 0 | 2 |
95 | 2 | 54 | 15 2002 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 54(5):1537-1549 Janssen HLK; Haustermans KMG; Sprong D; Blommestijn G; Hofland I; Hoebers FJ; Blijweert E; Raleigh JA; Semenza GL; Varia MA; Balm AJ; van Velthuysen MLF; Delaere P; Sciot R; Begg AC HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors | 3 | 8 |
96 | 2 | 5 | 94 2003 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 56(4):917-919 Begg AC Is HIF-1 alpha a good marker for tumor hypoxia? | 0 | 1 |
97 | 1 | 52 | 177 2004 JOURNAL OF APPLIED PHYSIOLOGY 96(3):1173-1177 Semenza GL O-2-regulated gene expression: transcriptional control of cardiorespiratory physiology by HIF-1 | 1 | 1 |
98 | 4 | 99 | 95 2003 JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 36(1):120-127 Choi KS; Bae MK; Jeong JW; Moon HE; Kim KW Hypoxia-induced angiogenesis during carcinogenesis | 0 | 6 |
99 | 1 | 26 | 16 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(26):23508-23514 Gradin K; Takasaki C; Fujii-Kuriyama Y; Sogawa K The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine | 10 | 13 |
100 | 3 | 32 | 17 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(29):26351-26355 Hewitson KS; McNeill LA; Riordan MV; Tian YM; Bullock AN; Welford RW; Elkins JM; Oldham NJ; Bhattacharya S; Gleadle JM; Ratcliffe PJ; Pugh CW; Schofield CJ Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family | 61 | 81 |
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