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Tue Sep 14 12:24:08 2004

ASPARAGINE HYDROXYLATION OF THE HIF TRANSACTIVATION DOMAIN: A HYPOXIC SWITCH
LANDO D; PEET DJ; WHELAN DA; GORMAN JJ; WHITELAW ML
SCIENCE 295:(5556)858-861 FEB 1 2002
and the citing papers

Nodes: 199
Authors: 610, Journals: 112, Outer References: 6717
Collection span: 2002 - 2004
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#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
111642 2002 FEB 1 SCIENCE 295(5556):807-808
Bruick RK; McKnight SL
Transcription - Oxygen sensing gets a second wind
1428
202843 2002 FEB 1 SCIENCE 295(5556):858-861
Lando D; Peet DJ; Whelan DA; Gorman JJ; Whitelaw ML
Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch
198198
31264 2002 MAR [15] BULLETIN DU CANCER 89(3):257-260
L'Allemain G
The hypoxia-inducible factor HIF as a new target in cancer research
02
415024 2002 APR 15 JOURNAL OF EXPERIMENTAL ZOOLOGY 294(1):17-29
Powell WH; Hahn ME
Identification and functional characterization of hypoxia-inducible factor 2 alpha from the estuarine teleost, Fundulus heteroclitus: Interaction of HIF-2 alpha with two ARNT2 splice variants
02
514534 2002 APR 16 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(8):5271-5276
Dames SA; Martinez-Yamout M; De Guzman RN; Dyson HJ; Wright PE
Structural basis for Hif-1 alpha/CBP recognition in the cellular hypoxic response
3145
614235 2002 APR 16 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(8):5367-5372
Freedman SJ; Sun ZYJ; Poy F; Kung AL; Livingston DM; Wagner G; Eck MJ
Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha
3558
7111127 2002 MAY-JUN [MAY 15] MASS SPECTROMETRY REVIEWS 21(3):183-216
Gorman JJ; Wallis TP; Pitt JJ
Protein disulfide bond determination by mass spectrometry
08
811178 2002 JUN [15] EXPERT OPINION ON THERAPEUTIC PATENTS 12(6):777-788
Mabjeesh NJ; Frazier MC; Simons JW; Zhong H
Hypoxia-directed cancer therapy
11
934113 2002 JUN 15 GENES & DEVELOPMENT 16(12):1441-1445
Kaelin WG
How oxygen makes its presence felt
831
1012616 2002 JUN 28 JOURNAL OF BIOLOGICAL CHEMISTRY 277(26):23508-23514
Gradin K; Takasaki C; Fujii-Kuriyama Y; Sogawa K
The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine
1013
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
111493 2002 [JUN 30] BLOOD PURIFICATION 20(5):445-450
Ratcliffe PJ
From erythropoietin to oxygen: Hypoxia-inducible factor hydroxylases and the hypoxia signal pathway
36
1213746 2002 [JUN 30] TRENDS IN MOLECULAR MEDICINE 8(4):S62-S67
Semenza GL
HIF-1 and tumor progression: pathophysiology and therapeutics
079
133544 2002 JUL 8 SCIENTIST 16(14):40-40
Maher BA
Faculty of 1000 - Hypoxic response takes shape
11
1417036 2002 JUL 9 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(14):9480-9485
Su H; Arakawa-Hoyt J; Kan YW
Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model
113
1533217 2002 JUL 19 JOURNAL OF BIOLOGICAL CHEMISTRY 277(29):26351-26355
Hewitson KS; McNeill LA; Riordan MV; Tian YM; Bullock AN; Welford RW; Elkins JM; Oldham NJ; Bhattacharya S; Gleadle JM; Ratcliffe PJ; Pugh CW; Schofield CJ
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family
6181
1612937 2002 AUG 6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10423-10428
Willam C; Masson N; Tian YM; Mahmood SA; Wilson MI; Bicknell R; Eckardt KU; Maxwell PH; Ratcliffe PJ; Pugh CW
Peptide blockade of HIF alpha degradation modulates cellular metabolism and angiogenesis
1625
171327 2002 AUG-SEP [AUG 15] EXPERIMENTAL GERONTOLOGY 37(8-9):1077-1088
Trubiani O; Di Giulio C; Tripodi D; Bianchi G; Paganelli R; Di Primio R
Thymic sensitivity to hypoxic condition in young and old rats. Age-dependent expression of NF-kappa B
02
1811789 2002 AUG [15] FASEB JOURNAL 16(10)
Wenger RH
Cellular adaptation to hypoxia: O-2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O-2-regulated gene expression
0117
1918018 2002 AUG 16 JOURNAL OF BIOLOGICAL CHEMISTRY 277(33):29936-29944
Isaacs JS; Jung YJ; Mimnaugh EG; Martinez A; Cuttitta F; Neckers LM
Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway
1953
2013932 2002 AUG 31 MOLECULES AND CELLS 14(1):9-15
Lee E; Yim S; Lee SK; Park H
Two transactivation domains of hypoxia-inducible factor-1 alpha regulated by the MEK-1/p42/p44 MAPK pathway
03
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
211645 2002 SEP 1 CANCER RESEARCH 62(17):5089-5095
Welsh SJ; Bellamy WT; Briehl MA; Powis G
The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1 alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis
415
2233838 2002 SEP 3 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(18):11570-11572
Semenza GL
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1 alpha with p300 and CBP
35
2311919 2002 SEP 6 JOURNAL OF BIOLOGICAL CHEMISTRY 277(36):32405-32408
Makino Y; Kanopka A; Wilson WJ; Tanaka H; Poellinger L
Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3 alpha locus
1933
24118325 2002 SEP [15] JOURNAL OF MOLECULAR MEDICINE-JMM 80(9):562-575
Acker T; Plate KH
A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology
29
25218828 2002 SEP-OCT [SEP 15] MASS SPECTROMETRY REVIEWS 21(5):305-348
Rusconi F; Guillonneau F; Praseuth D
Contributions of mass spectrometry in the study of nucleic acid-binding proteins and of nucleic acid-protein interactions
03
26514433 2002 SEP [15] NATURE REVIEWS CANCER 2(9):673-682
Kaelin WG
Molecular basis of the VHL hereditary cancer syndrome
1159
2744720 2002 OCT 11 JOURNAL OF BIOLOGICAL CHEMISTRY 277(41):38723-38730
Ruas JL; Poellinger L; Pereira T
Functional analysis of hypoxia-inducible factor-1 alpha-mediated transactivation - identification of amino acid residues critical for transcriptional activation and/or interaction with CREB-binding protein
910
2815729 2002 OCT [15] METHODS 28(2):259-266
Tang Y; Schmitt-Ott K; Qian KP; Kagiyama S; Phillips MI
Vigilant vectors: adeno-associated virus with a biosensor to switch on amplified therapeutic genes in specific tissues in life-threatening diseases
13
2915730 2002 OCT [15] MOLECULAR AND CELLULAR BIOLOGY 22(19):6842-6853
Lavista-Llanos S; Centanin L; Irisarri M; Russo DM; Gleadle JM; Bocca SN; Muzzopappa M; Ratcliffe PJ; Wappner P
Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar
1123
3025231 2002 OCT [15] MOLECULAR AND CELLULAR BIOLOGY 22(20):7004-7014
Hudson CC; Liu M; Chiang GG; Otterness DM; Loomis DC; Kaper F; Giaccia AJ; Abraham RT
Regulation of hypoxia-inducible factor 1 alpha expression and function by the mammalian target of rapamycin
641
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
3123939 2002 OCT 15 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(21):13459-13464
Ivan M; Haberberger T; Gervasi DC; Michelson KS; Gunzler V; Kondo K; Yang HF; Sorokina I; Conaway RC; Conaway JW; Kaelin WG
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2548
3222421 2002 OCT 18 JOURNAL OF BIOLOGICAL CHEMISTRY 277(42):40112-40117
Chan DA; Sutphin PD; Denko NC; Giaccia AJ
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1 alpha
1731
3312211 2002 OCT 23 FEBS LETTERS 530(1-3):186-190
Saarikoski ST; Rivera SP; Hankinson O
Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia
14
344312 2002 NOV 1 BIOCHEMICAL JOURNAL 367:571-575
McNeill LA; Hewitson KS; Claridge TD; Seibel JF; Horsfall LE; Schofield CJ
Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803
1722
35112512 2002 NOV 1 FREE RADICAL BIOLOGY AND MEDICINE 33(9):1231-1242
Michiels C; Minet E; Mottet D; Raes M
Regulation of gene expression by oxygen: NF-kappa B and HIF-1, two extremes
011
3655322 2002 NOV 1 JOURNAL OF BIOLOGICAL CHEMISTRY 277(44):41750-41755
Huang LE; Pete EA; Schau M; Milligan J; Gu J
Leu-574 of HIF-1 alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway
47
371261 2002 NOV [15] AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 283(5):L918-L921
Schumacker PT
Hypoxia, anoxia, and O-2 sensing: the search continues
05
3823310 2002 NOV [15] FASEB JOURNAL 16(13)
La Ferla K; Reimann C; Jelkmann W; Hellwig-Burgel T
Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kappa B
00
39112026 2002 NOV [15] JOURNAL OF MOLECULAR MEDICINE-JMM 80(11):703-714
Kim KR; Moon HE; Kim KW
Hypoxia-induced angiogenesis in human hepatocellular carcinoma
01
4025945 2002 NOV [15] TRENDS IN CARDIOVASCULAR MEDICINE 12(8):362-367
Vincent KA; Feron O; Kelly RA
Harnessing the response to tissue hypoxia - HIF-1 alpha and therapeutic angiogenesis
13
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
41219141 2002 NOV 22 RESPIRATORY RESEARCH 3(1)
Haddad JJ
Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology
06
4224240 2002 NOV 26 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(24):15351-15356
Dann CE; Bruick RK; Deisenhofer J
Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway
2027
432496 2002 NOV 27 CELL 111(5):709-720
Jeong JW; Bae MK; Ahn MY; Kim SH; Sohn TK; Bae MH; Yoo MA; Song EJ; Lee KJ; Kim KW
Regulation and destabilization of HIF-1 alpha by ARD1-mediated acetylation
2343
441414 2002 DEC 1 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 54(5):1299-1301
Brown JM; Le QT
Tumor hypoxia is important in radiotherapy, but how should we measure it?
02
4525415 2002 DEC 1 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 54(5):1537-1549
Janssen HLK; Haustermans KMG; Sprong D; Blommestijn G; Hofland I; Hoebers FJ; Blijweert E; Raleigh JA; Semenza GL; Varia MA; Balm AJ; van Velthuysen MLF; Delaere P; Sciot R; Begg AC
HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors
38
4615923 2002 DEC [15] JOURNAL OF EXPERIMENTAL BIOLOGY 205(23):3579-3586
Bickler PE; Donohoe PH
Adaptive responses of vertebrate neurons to hypoxia
07
4717847 2002 DEC [15] TRENDS IN PHARMACOLOGICAL SCIENCES 23(12):576-582
Bikfalvi A; Bicknell R
Recent advances in angiogenesis, anti-angiogenesis and vascular targeting
019
4816163 2003 JAN [15] CANCER CELL 3(1):75-88
Mack FA; Rathmell WK; Arsham AM; Gnarra J; Keith B; Simon MC
Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth
616
4914371 2003 JAN [15] CLINICAL CANCER RESEARCH 9(1):433-440
Park JH; Kim TY; Jong HS; Kim TY; Chun YS; Park JW; Lee CT; Jung HC; Kim NK; Bang YJ
Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1 alpha in gastric cancer cells
12
50212889 2003 JAN [15] FRONTIERS IN BIOSCIENCE 8:D100-D116
Brat DJ; Kaur B; Van Meir EG
Genetic modulation of hypoxia induced gene expression and angiogenesis: Relevance to brain tumors
05
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
51142118 2003 JAN [15] MOLECULAR AND CELLULAR BIOLOGY 23(1):359-369
Goda N; Ryan HE; Khadivi B; McNulty W; Rickert RC; Johnson RS
Hypoxia-inducible factor 1 alpha is essential for cell cycle arrest during hypoxia
624
52113059 2003 JAN 20 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1619(2):113-124
Templeton DM; Liu Y
Genetic regulation of cell function in response to iron overload or chelation
06
5349995 2003 JAN 31 JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 36(1):120-127
Choi KS; Bae MK; Jeong JW; Moon HE; Kim KW
Hypoxia-induced angiogenesis during carcinogenesis
06
5428362 2003 FEB 1 BLOOD 101(3):907-914
Kietzmann T; Samoylenko A; Roth U; Jungermann K
Hypoxia-inducible factor-1 and hypoxia response elements mediate the induction of plasminogen activator inhibitor-1 gene expression by insulin in primary rat hepatocytes
17
5514448 2003 FEB [15] AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 284(2):C439-C446
Zhou J; Fandrey J; Schumann J; Tiegs G; Brune B
NO and TNF-alpha released from activated macrophages stabilize HIF-1 alpha in resting tubular LLC-PK1 cells
07
5619052 2003 FEB [15] ANTIOXIDANTS & REDOX SIGNALING 5(1):123-132
Dulak J; Jozkowicz A
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07
57311866 2003 FEB [15] CELLULAR AND MOLECULAR BIOLOGY 49(1):77-87
Karhausen J; Ibla JC; Colgan SP
Implications of hypoxia on mucosal barrier function
11
5886076 2003 FEB [15] CURRENT OPINION IN GENETICS & DEVELOPMENT 13(1):55-60
Kim W; Kaelin WG
The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer
211
5916083 2003 FEB [15] FASEB JOURNAL 17(2)
Linden T; Katschinski DM; Eckhardt K; Scheid A; Pagel H; Wenger RH
The antimycotic ciclopirox olamine induces HIF-1 alpha stability, VEGF expression, and angiogenesis
00
60155132 2003 FEB-MAR [FEB 15] PLACENTA 24(2-3):199-208
Rajakumar A; Doty K; Daftary A; Harger G; Conrad KP
Impaired oxygen-dependent reduction of HIF-1 alpha and -2 alpha proteins in pre-eclamptic placentae
47
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
61278138 2003 FEB [15] SEMINARS IN CANCER BIOLOGY 13(1):83-89
Pugh CW; Ratcliffe PJ
The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
321
6233796 2003 FEB 28 JOURNAL OF BIOLOGICAL CHEMISTRY 278(9):6816-6823
Pereira T; Zheng XW; Ruas JL; Tanimoto K; Poellinger L
Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor gene product
38
6343997 2003 FEB 28 JOURNAL OF BIOLOGICAL CHEMISTRY 278(9):7558-7563
Lee C; Kim SJ; Jeong DG; Lee SM; Ryu SE
Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau
1014
64712181 2003 MAR [15] EUROPEAN JOURNAL OF BIOCHEMISTRY 270(5):781-790
Lando D; Gorman JJ; Whitelaw ML; Peet DJ
Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation
916
6546982 2003 MAR [15] EUROPEAN JOURNAL OF BIOCHEMISTRY 270(5):791-798
Bilton RL; Booker GW
The subtle side to hypoxia inducible factor (HIF alpha) regulation
511
66150111 2003 MAR [15] JOURNAL OF CLINICAL INVESTIGATION 111(5):571-574
Soberman RJ
The expanding network of redox signaling: new observations, complexities, and perspectives
08
67675112 2003 MAR [15] JOURNAL OF CLINICAL INVESTIGATION 111(6):779-783
Safran M; Kaelin WG
HIF hydroxylation and the mammalian oxygen-sensing pathway
123
68374124 2003 MAR [15] MOLECULAR CANCER THERAPEUTICS 2(3):235-243
Welsh SJ; Williams RR; Birmingham A; Newman DJ; Kirkpatrick DL; Powis G
The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1 alpha and vascular endothelial growth factor formation
412
69442108 2003 APR 1 JOURNAL OF CELL SCIENCE 116(7):1319-1326
Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Burgel T; Jelkmann W; Acker H; Fandrey J
Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing
922
7042354 2003 APR 11 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 303(3):947-953
Cioffi CL; Liu XQ; Kosinski PA; Garay M; Bowen BR
Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells
816
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
7125849 2003 APR 15 ANNALS OF INTERNAL MEDICINE 138(8):659-668
Brat DJ; Mapstone TB
Malignant glioma physiology: Cellular response to hypoxia and its role in tumor progression
03
7214558 2003 APR 15 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1626(1-3):10-18
Graven KK; Bellur D; Klahn BD; Lowrey SL; Amberger E
HIF-2 alpha regulates glyceraldehyde-3-phosphate dehydrogenase expression in endothelial cells
14
7315279 2003 APR 15 EMBO JOURNAL 22(8):1857-1867
Li ZB; Wang DK; Na X; Schoen SR; Messing EM; Wu G
The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1 alpha transcriptional activity
35
7434584 2003 APR [15] FASEB JOURNAL 17(6)
Warnecke C; Griethe W; Weidemann A; Jurgensen JS; Willam C; Bachmann S; Ivashchenko Y; Wagner I; Frei U; Wiesener M; Eckardt KU
Activation of the hypoxia-inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors
00
75153140 2003 APR [15] THROMBOSIS AND HAEMOSTASIS 89(4):666-673
Kietzmann T; Jungermann K; Gorlach A
Regulation of the hypoxia-dependent plasminogen activator inhibitor I expression by MAP kinases
04
7655598 2003 APR 18 JOURNAL OF BIOLOGICAL CHEMISTRY 278(16):14013-14019
Sang NL; Stiehl DP; Bohensky J; Leshchinsky I; Srinivas V; Caro J
MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
620
77214136 2003 APR 21 SCIENTIST 17(8):34-35
Russo E
Discovering HIF regulation
00
78118115 2003 APR 23 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(16):4710-4711
Kinzie SD; Thevis M; Ngo K; Whitelegge J; Loo JA; Abu-Omar MM
Posttranslational hydroxylation of human phenylalanine hydroxylase is a novel example of enzyme self-repair within the second coordination sphere of catalytic iron
02
7912399 2003 MAY 2 JOURNAL OF BIOLOGICAL CHEMISTRY 278(18):15911-15916
Yuan Y; Hilliard G; Ferguson T; Millhorn DE
Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha
319
8033160 2003 MAY [15] BIOESSAYS 25(5):515-519
Hochachka PW; Rupert JL
Fine tuning the HIF-1 'global' O-2 sensor for hypobaric hypoxia in Andean high-altitude natives
01
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
8138173 2003 MAY [15] CURRENT MEDICINAL CHEMISTRY 10(10):845-855
Brune B; Zhou J
The role of nitric oxide (NO) in stability regulation of hypoxia inducible factor-1 alpha (HIF-1 alpha)
14
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Hypoxia-inducible factor and its biomedical relevance
921
83134101 2003 MAY 30 JOURNAL OF BIOLOGICAL CHEMISTRY 278(22):20235-20239
Wright G; Higgin JJ; Raines RT; Steenbergen C; Murphy E
Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes
23
84149109 2003 JUN 1 JOURNAL OF CELL SCIENCE 116(11):2247-2260
Turcotte S; Desrosiers RR; Beliveau R
HIF-1 alpha mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma
25
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Hewitson KS; McNeill LA; Elkins JM; Schofield CJ
The role of iron and 2-oxoglutarate oxygenases in signalling
24
86714674 2003 JUN [15] CURRENT MEDICINAL CHEMISTRY 10(12):1005-1019
Hanauske-Abel HM; Popowicz AM
The HAG mechanism: A molecular rationale for the therapeutic application of iron chelators in human diseases involving the 2-oxoacid utilizing dioxygenases
00
87235122 2003 JUN [15] MOLECULAR BIOLOGY OF THE CELL 14(6):2216-2225
Zhou J; Schmid T; Brune B
Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1 alpha through a nuclear factor-kappa B-dependent pathway
34
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Pugh CW; Ratcliffe PJ
Regulation of angiogenesis by hypoxia: role of the HIF system
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89159102 2003 JUN 20 JOURNAL OF BIOLOGICAL CHEMISTRY 278(25):22316-22324
Del Toro R; Levitsky KL; Lopez-Barneo J; Chiara MD
Induction of T-type calcium channel gene expression by chronic hypoxia
05
9067150 2003 [JUN 30] ANNALS OF MEDICINE 35(3):183-190
Wiesener MS; Maxwell PH
HIF and oxygen sensing; as important to life as the air we breathe?
16
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
91510951 2003 [JUN 30] ANNALS OF MEDICINE 35(6):380-390
Pugh CW
Oxygen sensing in cancer
00
9213268 2003 [JUN 30] CHEMORECEPTION: FROM CELLULAR SIGNALLING TO FUNCTIONAL PLASTICITY 536:65-73
Ortega-Saenz P; Garcia-Fernandez M; Pardal R; Alvarez E; Lopez-Barneo J
Studies on glomus cell sensitivity to hypoxia in carotid body slices
01
93113470 2003 [JUN 30] CLINICAL & EXPERIMENTAL METASTASIS 20(3):237-250
Subarsky P; Hill RP
The hypoxic tumour microenvironment and metastatic progression
012
94516793 2003 [JUN 30] HYPOXIA: THROUGH THE LIFECYCLE 543:89-115
Hopfl G; Ogunshola O; Gassmann M
Hypoxia and high altitude - The molecular response
01
95140131 2003 [JUN 30] NEOPLASMA 50(1):13-21
Chrastina A; Pastorekova S; Pastorek J
Immunotargeting of human cervical carcinoma xenograft expressing CA IX tumor-associated antigen by I-125-labeled M75 monoclonal antibody
02
96121134 2003 [JUN 30] RAPID COMMUNICATIONS IN MASS SPECTROMETRY 17(5):371-376
Hirota J; Satomi Y; Yoshikawa K; Takao T
epsilon-N,N,N-Trimethyllysine-specific ions in matrix-assisted laser desorption/ionization-tandem mass spectrometry
02
97297135 2003 [JUN 30] REDOX REPORT 8(6):325-340
Land SC
Oxygen-sensing pathways and the development of mammalian gas exchange
00
98272141 2003 [JUN 30] TOR-TARGET OF RAPAMYCIN 279:299-319
Abraham RT
MTOR as a positive regulator of tumor cell responses to hypoxia
00
992107116 2003 JUL 2 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(26):7828-7842
Mehn MP; Fujisawa K; Hegg EL; Que L
Oxygen activation by nonheme iron(II) complexes: alpha-keto carboxylate versus carboxylate
110
1001126067 2003 JUL [15] CELLULAR AND MOLECULAR LIFE SCIENCES 60(7):1376-1393
Bracken CP; Whitelaw ML; Peet DJ
The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses
24

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