| Missing Links? Citation Matrix | Graphs | Glossary HistCite Guide About |
| ASPARAGINE HYDROXYLATION OF THE HIF TRANSACTIVATION DOMAIN: A HYPOXIC SWITCH
LANDO D; PEET DJ; WHELAN DA; GORMAN JJ; WHITELAW ML SCIENCE 295:(5556)858-861 FEB 1 2002 and the citing papers |
Nodes: 199
Authors: 610,
Journals: 112,
Outer References: 6717
Collection span: 2002 - 2004
View: Overview. Sorted by NCR.
Page 2: 1 (513) 2 (53)
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 101 | 1 | 53 | 140 2003 THROMBOSIS AND HAEMOSTASIS 89(4):666-673 Kietzmann T; Jungermann K; Gorlach A Regulation of the hypoxia-dependent plasminogen activator inhibitor I expression by MAP kinases | 0 | 4 |
| 102 | 2 | 52 | 31 2002 MOLECULAR AND CELLULAR BIOLOGY 22(20):7004-7014 Hudson CC; Liu M; Chiang GG; Otterness DM; Loomis DC; Kaper F; Giaccia AJ; Abraham RT Regulation of hypoxia-inducible factor 1 alpha expression and function by the mammalian target of rapamycin | 6 | 41 |
| 103 | 1 | 52 | 79 2003 EMBO JOURNAL 22(8):1857-1867 Li ZB; Wang DK; Na X; Schoen SR; Messing EM; Wu G The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1 alpha transcriptional activity | 3 | 5 |
| 104 | 1 | 52 | 175 2004 FREE RADICAL BIOLOGY AND MEDICINE 36(10):1279-1288 Goyal P; Weissmann N; Grimminger F; Hegel C; Bader L; Rose F; Fink L; Ghofrani HA; Schermuly RT; Schmidt HHHW; Seeger W; Hanze J Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxiainducible factor 1 via increase in reactive oxygen species | 0 | 0 |
| 105 | 1 | 52 | 177 2004 JOURNAL OF APPLIED PHYSIOLOGY 96(3):1173-1177 Semenza GL O-2-regulated gene expression: transcriptional control of cardiorespiratory physiology by HIF-1 | 1 | 1 |
| 106 | 3 | 51 | 107 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(41):40296-40304 Leonard MO; Cottell DC; Godson C; Brady HR; Taylor CT The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia | 0 | 3 |
| 107 | 1 | 51 | 159 2004 CANCER RESEARCH 64(5):1765-1772 Mizukami Y; Li JN; Zhang XB; Zimmer MA; Iliopoulos O; Chung DC Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer | 0 | 0 |
| 108 | 1 | 50 | 24 2002 JOURNAL OF EXPERIMENTAL ZOOLOGY 294(1):17-29 Powell WH; Hahn ME Identification and functional characterization of hypoxia-inducible factor 2 alpha from the estuarine teleost, Fundulus heteroclitus: Interaction of HIF-2 alpha with two ARNT2 splice variants | 0 | 2 |
| 109 | 2 | 50 | 64 2003 CANCER SCIENCE 94(12):1021-1028 Kizaka-Kondoh S; Inoue M; Harada H; Hiraoka M Tumor hypoxia: A target for selective cancer therapy | 0 | 2 |
| 110 | 1 | 50 | 78 2003 CURRENT OPINION IN NEUROBIOLOGY 13(4):493-499 Lopez-Barneo J Oxygen and glucose sensing by carotid body glomus cells | 0 | 4 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 111 | 1 | 50 | 111 2003 JOURNAL OF CLINICAL INVESTIGATION 111(5):571-574 Soberman RJ The expanding network of redox signaling: new observations, complexities, and perspectives | 0 | 8 |
| 112 | 1 | 49 | 3 2002 BLOOD PURIFICATION 20(5):445-450 Ratcliffe PJ From erythropoietin to oxygen: Hypoxia-inducible factor hydroxylases and the hypoxia signal pathway | 3 | 6 |
| 113 | 2 | 49 | 6 2002 CELL 111(5):709-720 Jeong JW; Bae MK; Ahn MY; Kim SH; Sohn TK; Bae MH; Yoo MA; Song EJ; Lee KJ; Kim KW Regulation and destabilization of HIF-1 alpha by ARD1-mediated acetylation | 23 | 43 |
| 114 | 7 | 49 | 80 2003 EMBO JOURNAL 22(16):4082-4090 Berra E; Benizri E; Ginouves A; Volmat V; Roux D; Pouyssegur J HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1 alpha in normoxia | 10 | 25 |
| 115 | 1 | 49 | 109 2003 JOURNAL OF CELL SCIENCE 116(11):2247-2260 Turcotte S; Desrosiers RR; Beliveau R HIF-1 alpha mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma | 2 | 5 |
| 116 | 4 | 49 | 119 2003 MOLECULAR AND CELLULAR BIOLOGY 23(14):4959-4971 Park SK; Dadak AM; Haase VH; Fontana L; Giaccia AJ; Johnson RS Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1 alpha (HIF-1 alpha): Role of cytoplasmic trapping of HIF-2 alpha | 5 | 14 |
| 117 | 8 | 48 | 130 2003 NATURE STRUCTURAL BIOLOGY 10(7):504-512 Freedman SJ; Sun ZYJ; Kung AL; France DS; Wagner G; Eck MJ Structural basis for negative regulation of hypoxia-inducible factor-1 alpha by CITED2 | 2 | 6 |
| 118 | 2 | 48 | 172 2004 FASEB JOURNAL 18(10) Jurgensen JS; Rosenberger C; Wiesener MS; Warnecke C; Horstrup JH; Grafe M; Philipp S; Griethe W; Maxwell PH; Frei U; Bachmann S; Willenbrock R; Eckardt KU Persistent induction of HIF-1 alpha and -2 alpha in cardiomyocytes and stromal cells of ischemic myocardium | 0 | 0 |
| 119 | 4 | 47 | 20 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(41):38723-38730 Ruas JL; Poellinger L; Pereira T Functional analysis of hypoxia-inducible factor-1 alpha-mediated transactivation - identification of amino acid residues critical for transcriptional activation and/or interaction with CREB-binding protein | 9 | 10 |
| 120 | 1 | 46 | 114 2003 JOURNAL OF IMMUNOLOGY 171(12):6534-6540 Makino Y; Nakamura H; Ikeda E; Ohnuma K; Yamauchi K; Yabe Y; Poellinger L; Okada Y; Morimoto C; Tanaka H Hypoxia-inducible factor regulates survival of antigen receptor-driven T cells | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 1 | 45 | 34 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(8):5271-5276 Dames SA; Martinez-Yamout M; De Guzman RN; Dyson HJ; Wright PE Structural basis for Hif-1 alpha/CBP recognition in the cellular hypoxic response | 31 | 45 |
| 122 | 1 | 45 | 58 2003 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1626(1-3):10-18 Graven KK; Bellur D; Klahn BD; Lowrey SL; Amberger E HIF-2 alpha regulates glyceraldehyde-3-phosphate dehydrogenase expression in endothelial cells | 1 | 4 |
| 123 | 3 | 45 | 84 2003 FASEB JOURNAL 17(6) Warnecke C; Griethe W; Weidemann A; Jurgensen JS; Willam C; Bachmann S; Ivashchenko Y; Wagner I; Frei U; Wiesener M; Eckardt KU Activation of the hypoxia-inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors | 0 | 0 |
| 124 | 8 | 45 | 164 2004 CURRENT OPINION IN GENETICS & DEVELOPMENT 14(1):81-85 Poellinger L; Johnson RS HIF-1 and hypoxic response: the plot thickens | 0 | 0 |
| 125 | 1 | 45 | 193 2004 PEDIATRIC RESEARCH 55(3):385-394 Wang XH; Deng JX; Boyle DW; Zhong J; Lee WH Potential role of IGF-I in hypoxia tolerance using a rat hypoxic-ischemic model: Activation of hypoxia-inducible factor 1 alpha | 0 | 0 |
| 126 | 1 | 44 | 48 2003 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 284(2):C439-C446 Zhou J; Fandrey J; Schumann J; Tiegs G; Brune B NO and TNF-alpha released from activated macrophages stabilize HIF-1 alpha in resting tubular LLC-PK1 cells | 0 | 7 |
| 127 | 5 | 44 | 57 2003 BIOCHEMISTRY 42(33):9937-9945 Dial R; Sun ZYJ; Freedman SJ Three conformational states of the p300 CH1 domain define its functional properties | 0 | 1 |
| 128 | 5 | 44 | 171 2004 FASEB JOURNAL 18(10) Warnecke C; Zaborowska Z; Kurreck J; Erdmann VA; Frei U; Wiesener M; Eckardt KU Differentiating the functional role of hypoxia-inducible factor (HIF)-1 alpha and HIF-2 alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2 alpha target gene in Hep3B and Kelly cells | 0 | 0 |
| 129 | 1 | 43 | 71 2003 CLINICAL CANCER RESEARCH 9(1):433-440 Park JH; Kim TY; Jong HS; Kim TY; Chun YS; Park JW; Lee CT; Jung HC; Kim NK; Bang YJ Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1 alpha in gastric cancer cells | 1 | 2 |
| 130 | 3 | 43 | 90 2003 GENE THERAPY 10(25):2081-2089 Sun X; Kanwar JR; Leung E; Vale M; Krissansen GW Regression of solid tumors by engineered overexpression of von Hippel-Lindau tumor suppressor protein and antisense hypoxia-inducible factor-1 alpha | 1 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 131 | 11 | 43 | 170 2004 FASEB JOURNAL 18(6) Kageyama Y; Koshiji M; To KKW; Tian YM; Ratcliffe PJ; Huang LE Leu-574 of human HIF-1a is a molecular determinant of prolyl hydroxylation | 0 | 0 |
| 132 | 1 | 42 | 35 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(8):5367-5372 Freedman SJ; Sun ZYJ; Poy F; Kung AL; Livingston DM; Wagner G; Eck MJ Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha | 35 | 58 |
| 133 | 2 | 42 | 40 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(24):15351-15356 Dann CE; Bruick RK; Deisenhofer J Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway | 20 | 27 |
| 134 | 4 | 42 | 108 2003 JOURNAL OF CELL SCIENCE 116(7):1319-1326 Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Burgel T; Jelkmann W; Acker H; Fandrey J Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing | 9 | 22 |
| 135 | 1 | 42 | 118 2003 MOLECULAR AND CELLULAR BIOLOGY 23(1):359-369 Goda N; Ryan HE; Khadivi B; McNulty W; Rickert RC; Johnson RS Hypoxia-inducible factor 1 alpha is essential for cell cycle arrest during hypoxia | 6 | 24 |
| 136 | 10 | 42 | 182 2004 JOURNAL OF CELLULAR BIOCHEMISTRY 92(3):491-501 Aprelikova O; Chandramouli GVR; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors | 0 | 0 |
| 137 | 3 | 41 | 13 2002 GENES & DEVELOPMENT 16(12):1441-1445 Kaelin WG How oxygen makes its presence felt | 8 | 31 |
| 138 | 2 | 41 | 120 2003 MOLECULAR AND CELLULAR BIOLOGY 23(19):6739-6749 Tomita S; Ueno M; Sakamoto M; Kitahama Y; Ueki M; Maekawa N; Sakamoto H; Gassmann M; Kageyama R; Ueda N; Gonzalez FJ; Takahama Y Defective brain development in mice lacking the Hif-1 alpha gene in neural cells | 3 | 4 |
| 139 | 5 | 41 | 180 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(14):13506-13513 Zhou J; Schmid T; Frank R; Brune B PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1 alpha from pVHL-independent degradation | 0 | 0 |
| 140 | 2 | 40 | 69 2003 CIRCULATION RESEARCH 93(11):1074-1081 Kelly BD; Hackett SF; Hirota K; Oshima Y; Cai ZQ; Berg-Dixon S; Rowan A; Yan ZJ; Campochiaro PA; Semenza GL Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1 | 1 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 141 | 1 | 40 | 131 2003 NEOPLASMA 50(1):13-21 Chrastina A; Pastorekova S; Pastorek J Immunotargeting of human cervical carcinoma xenograft expressing CA IX tumor-associated antigen by I-125-labeled M75 monoclonal antibody | 0 | 2 |
| 142 | 8 | 40 | 161 2004 CELL CYCLE 3(2):156-159 Maxwell PH HIF-1's relationship to oxygen - Simple yet sophisticated | 0 | 1 |
| 143 | 3 | 40 | 185 2004 MOLECULAR CANCER RESEARCH 2(1):43-52 Qi H; Gervais ML; Li W; DeCaprio JA; Challis JRG; Ohh M Molecular cloning and characterization of the von Hippel-Lindau-like protein | 0 | 0 |
| 144 | 1 | 40 | 194 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(12):4302-4307 Liu Q; Berchner-Pfannschmidt U; Moller U; Brecht M; Wotzlaw C; Acker H; Jungermann K; Kietzmann T A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression | 2 | 2 |
| 145 | 1 | 39 | 32 2002 MOLECULES AND CELLS 14(1):9-15 Lee E; Yim S; Lee SK; Park H Two transactivation domains of hypoxia-inducible factor-1 alpha regulated by the MEK-1/p42/p44 MAPK pathway | 0 | 3 |
| 146 | 2 | 39 | 39 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(21):13459-13464 Ivan M; Haberberger T; Gervasi DC; Michelson KS; Gunzler V; Kondo K; Yang HF; Sorokina I; Conaway RC; Conaway JW; Kaelin WG Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor | 25 | 48 |
| 147 | 1 | 39 | 92 2003 HISTOCHEMISTRY AND CELL BIOLOGY 120(5):343-352 Baby SM; Roy A; Mokashi AM; Lahiri S Effects of hypoxia and intracellular iron chelation on hypoxia-inducible factor-1 alpha and -1 beta in the rat carotid body and glomus cells | 1 | 3 |
| 148 | 4 | 39 | 97 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(9):7558-7563 Lee C; Kim SJ; Jeong DG; Lee SM; Ryu SE Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau | 10 | 14 |
| 149 | 3 | 38 | 38 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(18):11570-11572 Semenza GL Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1 alpha with p300 and CBP | 3 | 5 |
| 150 | 2 | 38 | 147 2004 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 287(3):R600-R607 Ma Y; Freitag P; Zhou J; Brune B; Frede S; Fandrey J Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1 | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 151 | 3 | 38 | 153 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 317(1):84-91 Takahashi R; Kobayashi C; Kondo Y; Nakatani Y; Kudo I; Kunimoto M; Imura N; Hara S Subcellular localization and regulation of hypoxia-inducible factor-2 alpha in vascular endothelial cells | 0 | 0 |
| 152 | 1 | 37 | 46 2002 TRENDS IN MOLECULAR MEDICINE 8(4):S62-S67 Semenza GL HIF-1 and tumor progression: pathophysiology and therapeutics | 0 | 79 |
| 153 | 3 | 37 | 96 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(9):6816-6823 Pereira T; Zheng XW; Ruas JL; Tanimoto K; Poellinger L Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor gene product | 3 | 8 |
| 154 | 2 | 37 | 157 2004 BIOLOGICAL CHEMISTRY 385(3-4):231-237 Berchner-Pfannschmidt U; Wotzlaw C; Merten E; Acker H; Fandrey J Visualization of the three-dimensional organization of hypoxia-inducible factor-1 alpha and interacting cofactors in subnuclear structures | 0 | 0 |
| 155 | 1 | 36 | 85 2003 FASEB JOURNAL 17(15) Moon EJ; Jeong CH; Jeong JW; Kim KR; Yu DY; Murakami S; Kim CW; Kim KW Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1 alpha | 0 | 0 |
| 156 | 4 | 36 | 104 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(34):31895-31901 Naranjo-Suarez S; Castellanos MC; Alvarez-Tejado M; Vara A; Landazuri MO; del Peso L Down-regulation of hypoxia-inducible factor-2 in PC12 cells by nerve growth factor stimulation | 0 | 2 |
| 157 | 2 | 35 | 122 2003 MOLECULAR BIOLOGY OF THE CELL 14(6):2216-2225 Zhou J; Schmid T; Brune B Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1 alpha through a nuclear factor-kappa B-dependent pathway | 3 | 4 |
| 158 | 10 | 35 | 181 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(14):14391-14397 Linke S; Stojkoski C; Kewley RJ; Booker GW; Whitelaw ML; Peet DJ Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor | 2 | 2 |
| 159 | 1 | 34 | 101 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(22):20235-20239 Wright G; Higgin JJ; Raines RT; Steenbergen C; Murphy E Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes | 2 | 3 |
| 160 | 2 | 34 | 125 2003 MOLECULAR PHARMACOLOGY 64(6):1485-1493 Davidson T; Salnikow K; Costa M Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 161 | 1 | 34 | 158 2004 CANCER RESEARCH 64(2):456-462 Datta K; Li JP; Bhattacharya R; Gasparian L; Wang EF; Mukhopadhyay D Protein kinase C zeta transactivates hypoxia-inducible factor alpha by promoting its association with p300 in renal cancer | 1 | 2 |
| 162 | 3 | 34 | 192 2004 OXYGEN SENSING 381:467-487 Peet DJ; Lando D; Whelan DA; Whitelaw ML; Gorman JJ Oxygen-dependent asparagine hydroxylation | 0 | 0 |
| 163 | 2 | 33 | 10 2002 FASEB JOURNAL 16(13) La Ferla K; Reimann C; Jelkmann W; Hellwig-Burgel T Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kappa B | 0 | 0 |
| 164 | 3 | 33 | 55 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 312(3):571-577 Hanze J; Eul BG; Savai R; Krick S; Goyal P; Grimminger F; Seeger W; Rose F RNA interference for HIF-1 alpha inhibits its downstream signalling and affects cellular proliferation | 2 | 3 |
| 165 | 1 | 32 | 7 2002 EXPERIMENTAL GERONTOLOGY 37(8-9):1077-1088 Trubiani O; Di Giulio C; Tripodi D; Bianchi G; Paganelli R; Di Primio R Thymic sensitivity to hypoxic condition in young and old rats. Age-dependent expression of NF-kappa B | 0 | 2 |
| 166 | 3 | 32 | 17 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(29):26351-26355 Hewitson KS; McNeill LA; Riordan MV; Tian YM; Bullock AN; Welford RW; Elkins JM; Oldham NJ; Bhattacharya S; Gleadle JM; Ratcliffe PJ; Pugh CW; Schofield CJ Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family | 61 | 81 |
| 167 | 1 | 32 | 68 2003 CHEMORECEPTION: FROM CELLULAR SIGNALLING TO FUNCTIONAL PLASTICITY 536:65-73 Ortega-Saenz P; Garcia-Fernandez M; Pardal R; Alvarez E; Lopez-Barneo J Studies on glomus cell sensitivity to hypoxia in carotid body slices | 0 | 1 |
| 168 | 5 | 32 | 178 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(4):3042-3049 De Guzman RN; Martinez-Yamout MA; Dyson HJ; Wright PE Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2 - Regulation by competition between intrinsically unstructured ligands for non-identical binding sites | 0 | 0 |
| 169 | 4 | 31 | 2 2002 BIOCHEMICAL JOURNAL 367:571-575 McNeill LA; Hewitson KS; Claridge TD; Seibel JF; Horsfall LE; Schofield CJ Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803 | 17 | 22 |
| 170 | 3 | 31 | 60 2003 BIOESSAYS 25(5):515-519 Hochachka PW; Rupert JL Fine tuning the HIF-1 'global' O-2 sensor for hypobaric hypoxia in Andean high-altitude natives | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 171 | 9 | 31 | 179 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(11):9899-9904 Koivunen P; Hirsila M; Gunzler V; Kivirikko KI; Myllyharju J Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases | 1 | 1 |
| 172 | 1 | 30 | 87 2003 FEBS LETTERS 554(3):264-270 Minchenko O; Opentanova I; Caro J Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo | 0 | 2 |
| 173 | 4 | 30 | 103 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(33):30772-30780 Hirsila M; Koivunen P; Gunzler V; Kivirikko KI; Myllyharju J Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor | 8 | 20 |
| 174 | 1 | 29 | 37 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10423-10428 Willam C; Masson N; Tian YM; Mahmood SA; Wilson MI; Bicknell R; Eckardt KU; Maxwell PH; Ratcliffe PJ; Pugh CW Peptide blockade of HIF alpha degradation modulates cellular metabolism and angiogenesis | 16 | 25 |
| 175 | 4 | 29 | 61 2003 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 13(16):2677-2680 Mole DR; Schlemminger I; McNeill LA; Hewitson KS; Pugh CW; Ratcliffe PJ; Schofield CJ 2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase | 3 | 3 |
| 176 | 0 | 28 | 43 2002 SCIENCE 295(5556):858-861 Lando D; Peet DJ; Whelan DA; Gorman JJ; Whitelaw ML Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch | 198 | 198 |
| 177 | 2 | 28 | 86 2003 FEBS LETTERS 549(1-3):105-109 Yasinska IM; Sumbayev VV S-nitrosation of Cys-800 of HIF-1 alpha protein activates its interaction with p300 and stimulates its transcriptional activity | 1 | 2 |
| 178 | 1 | 27 | 190 2004 OXYGEN SENSING 381:133-+ Roy S; Khanna S; Sen CK Perceived hyperoxia: Oxygen-regulated signal transduction pathways in the heart | 0 | 0 |
| 179 | 4 | 27 | 191 2004 OXYGEN SENSING 381:305-320 Masson N; Ratcliffe PJ Analysis of von Hippel-Lindau tumor suppressor as a mediator of cellular oxygen sensing | 0 | 0 |
| 180 | 3 | 27 | 196 2004 RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY 141(2):115-123 Roy A; Li JQ; Baby SM; Mokashi A; Buerk DG; Lahiri S Effects of iron-chelators on ion-channels and HIF-1 alpha in the carotid body | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 181 | 1 | 26 | 1 2002 AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 283(5):L918-L921 Schumacker PT Hypoxia, anoxia, and O-2 sensing: the search continues | 0 | 5 |
| 182 | 1 | 26 | 4 2002 BULLETIN DU CANCER 89(3):257-260 L'Allemain G The hypoxia-inducible factor HIF as a new target in cancer research | 0 | 2 |
| 183 | 1 | 26 | 16 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(26):23508-23514 Gradin K; Takasaki C; Fujii-Kuriyama Y; Sogawa K The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine | 10 | 13 |
| 184 | 2 | 24 | 21 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(42):40112-40117 Chan DA; Sutphin PD; Denko NC; Giaccia AJ Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1 alpha | 17 | 31 |
| 185 | 4 | 23 | 54 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 303(3):947-953 Cioffi CL; Liu XQ; Kosinski PA; Garay M; Bowen BR Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells | 8 | 16 |
| 186 | 1 | 23 | 99 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(18):15911-15916 Yuan Y; Hilliard G; Ferguson T; Millhorn DE Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha | 3 | 19 |
| 187 | 2 | 23 | 189 2004 ONCOGENE 23(13):2315-2323 Lewis MD; Roberts BJ Role of the C-terminal alpha-helical domain of the von Hippel-Lindau protein in its E3 ubiquitin ligase activity | 0 | 0 |
| 188 | 1 | 22 | 11 2002 FEBS LETTERS 530(1-3):186-190 Saarikoski ST; Rivera SP; Hankinson O Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia | 1 | 4 |
| 189 | 1 | 22 | 198 2004 THORAX 59(2):90-92 Walmsley SR; Sheares KKK; Sobolewski A; Morrell NW; Chilvers ER New insights into oxygen sensing at a cellular level | 0 | 0 |
| 190 | 1 | 21 | 134 2003 RAPID COMMUNICATIONS IN MASS SPECTROMETRY 17(5):371-376 Hirota J; Satomi Y; Yoshikawa K; Takao T epsilon-N,N,N-Trimethyllysine-specific ions in matrix-assisted laser desorption/ionization-tandem mass spectrometry | 0 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 191 | 1 | 21 | 154 2004 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1691(1):17-22 Daly EB; Wind T; Jiang XM; Sun L; Hogg PJ Secretion of phosphoglycerate kinase from tumour cells is controlled by oxygen-sensing hydroxylases | 0 | 0 |
| 192 | 1 | 19 | 19 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(36):32405-32408 Makino Y; Kanopka A; Wilson WJ; Tanaka H; Poellinger L Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3 alpha locus | 19 | 33 |
| 193 | 1 | 18 | 115 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(16):4710-4711 Kinzie SD; Thevis M; Ngo K; Whitelegge J; Loo JA; Abu-Omar MM Posttranslational hydroxylation of human phenylalanine hydroxylase is a novel example of enzyme self-repair within the second coordination sphere of catalytic iron | 0 | 2 |
| 194 | 1 | 16 | 42 2002 SCIENCE 295(5556):807-808 Bruick RK; McKnight SL Transcription - Oxygen sensing gets a second wind | 14 | 28 |
| 195 | 1 | 16 | 199 2004 TOXICOLOGY AND APPLIED PHARMACOLOGY 196(3):404-409 Zhao JH; Chen HB; Davidson T; Kluz T; Zhang QW; Costa M Nickel-induced 1,4-alpha-glucan branching enzyme 1 up-regulation via the hypoxic signaling pathway | 0 | 0 |
| 196 | 2 | 14 | 136 2003 SCIENTIST 17(8):34-35 Russo E Discovering HIF regulation | 0 | 0 |
| 197 | 3 | 5 | 44 2002 SCIENTIST 16(14):40-40 Maher BA Faculty of 1000 - Hypoxic response takes shape | 1 | 1 |
| 198 | 2 | 5 | 94 2003 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 56(4):917-919 Begg AC Is HIF-1 alpha a good marker for tumor hypoxia? | 0 | 1 |
| 199 | 1 | 4 | 14 2002 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 54(5):1299-1301 Brown JM; Le QT Tumor hypoxia is important in radiotherapy, but how should we measure it? | 0 | 2 |
Page 2: 1 (513) 2 (53)
Generated by: HistCite(Vlad).
Version: 2004.08.24