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| ASPARAGINE HYDROXYLATION OF THE HIF TRANSACTIVATION DOMAIN: A HYPOXIC SWITCH
LANDO D; PEET DJ; WHELAN DA; GORMAN JJ; WHITELAW ML SCIENCE 295:(5556)858-861 FEB 1 2002 and the citing papers |
Nodes: 199
Authors: 610,
Journals: 112,
Outer References: 6717
Collection span: 2002 - 2004
View: Overview. Sorted by LCR.
Page 2: 1 (24) 2 (2)
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 101 | 2 | 191 | 41 2002 RESPIRATORY RESEARCH 3(1) Haddad JJ Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology | 0 | 6 |
| 102 | 2 | 59 | 45 2002 TRENDS IN CARDIOVASCULAR MEDICINE 12(8):362-367 Vincent KA; Feron O; Kelly RA Harnessing the response to tissue hypoxia - HIF-1 alpha and therapeutic angiogenesis | 1 | 3 |
| 103 | 2 | 58 | 49 2003 ANNALS OF INTERNAL MEDICINE 138(8):659-668 Brat DJ; Mapstone TB Malignant glioma physiology: Cellular response to hypoxia and its role in tumor progression | 0 | 3 |
| 104 | 2 | 83 | 62 2003 BLOOD 101(3):907-914 Kietzmann T; Samoylenko A; Roth U; Jungermann K Hypoxia-inducible factor-1 and hypoxia response elements mediate the induction of plasminogen activator inhibitor-1 gene expression by insulin in primary rat hepatocytes | 1 | 7 |
| 105 | 2 | 50 | 64 2003 CANCER SCIENCE 94(12):1021-1028 Kizaka-Kondoh S; Inoue M; Harada H; Hiraoka M Tumor hypoxia: A target for selective cancer therapy | 0 | 2 |
| 106 | 2 | 40 | 69 2003 CIRCULATION RESEARCH 93(11):1074-1081 Kelly BD; Hackett SF; Hirota K; Oshima Y; Cai ZQ; Berg-Dixon S; Rowan A; Yan ZJ; Campochiaro PA; Semenza GL Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1 | 1 | 3 |
| 107 | 2 | 63 | 72 2003 CLINICAL CANCER RESEARCH 9(8):3150-3157 Palayoor ST; Tofilon PJ; Coleman CN Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1 alpha and HIF-2 alpha in prostate cancer cells | 0 | 2 |
| 108 | 2 | 28 | 86 2003 FEBS LETTERS 549(1-3):105-109 Yasinska IM; Sumbayev VV S-nitrosation of Cys-800 of HIF-1 alpha protein activates its interaction with p300 and stimulates its transcriptional activity | 1 | 2 |
| 109 | 2 | 202 | 88 2003 FREE RADICAL BIOLOGY AND MEDICINE 35(2):117-132 Chen K; Thomas SR; Keaney JF Beyond LDL oxidation: ROS in vascular signal transduction | 0 | 9 |
| 110 | 2 | 128 | 89 2003 FRONTIERS IN BIOSCIENCE 8:D100-D116 Brat DJ; Kaur B; Van Meir EG Genetic modulation of hypoxia induced gene expression and angiogenesis: Relevance to brain tumors | 0 | 5 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 111 | 2 | 5 | 94 2003 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 56(4):917-919 Begg AC Is HIF-1 alpha a good marker for tumor hypoxia? | 0 | 1 |
| 112 | 2 | 107 | 116 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(26):7828-7842 Mehn MP; Fujisawa K; Hegg EL; Que L Oxygen activation by nonheme iron(II) complexes: alpha-keto carboxylate versus carboxylate | 1 | 10 |
| 113 | 2 | 41 | 120 2003 MOLECULAR AND CELLULAR BIOLOGY 23(19):6739-6749 Tomita S; Ueno M; Sakamoto M; Kitahama Y; Ueki M; Maekawa N; Sakamoto H; Gassmann M; Kageyama R; Ueda N; Gonzalez FJ; Takahama Y Defective brain development in mice lacking the Hif-1 alpha gene in neural cells | 3 | 4 |
| 114 | 2 | 35 | 122 2003 MOLECULAR BIOLOGY OF THE CELL 14(6):2216-2225 Zhou J; Schmid T; Brune B Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1 alpha through a nuclear factor-kappa B-dependent pathway | 3 | 4 |
| 115 | 2 | 34 | 125 2003 MOLECULAR PHARMACOLOGY 64(6):1485-1493 Davidson T; Salnikow K; Costa M Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel | 0 | 0 |
| 116 | 2 | 97 | 135 2003 REDOX REPORT 8(6):325-340 Land SC Oxygen-sensing pathways and the development of mammalian gas exchange | 0 | 0 |
| 117 | 2 | 14 | 136 2003 SCIENTIST 17(8):34-35 Russo E Discovering HIF regulation | 0 | 0 |
| 118 | 2 | 78 | 138 2003 SEMINARS IN CANCER BIOLOGY 13(1):83-89 Pugh CW; Ratcliffe PJ The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis | 3 | 21 |
| 119 | 2 | 82 | 139 2003 STRAHLENTHERAPIE UND ONKOLOGIE 179(12):801-811 Vordermark D; Brown JM Endogenous markers of tumor hypoxia - Predictors of clinical radiation resistance? | 0 | 2 |
| 120 | 2 | 72 | 141 2003 TOR-TARGET OF RAPAMYCIN 279:299-319 Abraham RT MTOR as a positive regulator of tumor cell responses to hypoxia | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 2 | 55 | 142 2003 TRENDS IN ENDOCRINOLOGY AND METABOLISM 14(10):453-459 Baysal BE On the association of succinate dehydrogenase mutations with hereditary paraganglioma | 0 | 1 |
| 122 | 2 | 38 | 147 2004 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 287(3):R600-R607 Ma Y; Freitag P; Zhou J; Brune B; Frede S; Fandrey J Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1 | 0 | 0 |
| 123 | 2 | 71 | 152 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 316(4):969-977 Haddad JJ Oxygen sensing and oxidant/redox-related pathways | 0 | 0 |
| 124 | 2 | 37 | 157 2004 BIOLOGICAL CHEMISTRY 385(3-4):231-237 Berchner-Pfannschmidt U; Wotzlaw C; Merten E; Acker H; Fandrey J Visualization of the three-dimensional organization of hypoxia-inducible factor-1 alpha and interacting cofactors in subnuclear structures | 0 | 0 |
| 125 | 2 | 111 | 168 2004 EXPERT OPINION ON INVESTIGATIONAL DRUGS 13(7):829-839 Rebar EJ Development of proangiogenic engineered transcription factors for the treatment of cardiovascular disease | 0 | 0 |
| 126 | 2 | 48 | 172 2004 FASEB JOURNAL 18(10) Jurgensen JS; Rosenberger C; Wiesener MS; Warnecke C; Horstrup JH; Grafe M; Philipp S; Griethe W; Maxwell PH; Frei U; Bachmann S; Willenbrock R; Eckardt KU Persistent induction of HIF-1 alpha and -2 alpha in cardiomyocytes and stromal cells of ischemic myocardium | 0 | 0 |
| 127 | 2 | 23 | 189 2004 ONCOGENE 23(13):2315-2323 Lewis MD; Roberts BJ Role of the C-terminal alpha-helical domain of the von Hippel-Lindau protein in its E3 ubiquitin ligase activity | 0 | 0 |
| 128 | 2 | 58 | 195 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(28):10440-10445 Kong TQ; Eltzschig HK; Karhausen J; Colgan SP; Shelley CS Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction Of beta 2 integrin gene expression | 0 | 0 |
| 129 | 2 | 107 | 197 2004 SEMINARS IN CANCER BIOLOGY 14(2):123-130 Mukhopadhyay D; Datta K Multiple regulatory pathways of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in tumors | 0 | 0 |
| 130 | 1 | 26 | 1 2002 AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 283(5):L918-L921 Schumacker PT Hypoxia, anoxia, and O-2 sensing: the search continues | 0 | 5 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 131 | 1 | 49 | 3 2002 BLOOD PURIFICATION 20(5):445-450 Ratcliffe PJ From erythropoietin to oxygen: Hypoxia-inducible factor hydroxylases and the hypoxia signal pathway | 3 | 6 |
| 132 | 1 | 26 | 4 2002 BULLETIN DU CANCER 89(3):257-260 L'Allemain G The hypoxia-inducible factor HIF as a new target in cancer research | 0 | 2 |
| 133 | 1 | 64 | 5 2002 CANCER RESEARCH 62(17):5089-5095 Welsh SJ; Bellamy WT; Briehl MA; Powis G The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1 alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis | 4 | 15 |
| 134 | 1 | 32 | 7 2002 EXPERIMENTAL GERONTOLOGY 37(8-9):1077-1088 Trubiani O; Di Giulio C; Tripodi D; Bianchi G; Paganelli R; Di Primio R Thymic sensitivity to hypoxic condition in young and old rats. Age-dependent expression of NF-kappa B | 0 | 2 |
| 135 | 1 | 117 | 8 2002 EXPERT OPINION ON THERAPEUTIC PATENTS 12(6):777-788 Mabjeesh NJ; Frazier MC; Simons JW; Zhong H Hypoxia-directed cancer therapy | 1 | 1 |
| 136 | 1 | 178 | 9 2002 FASEB JOURNAL 16(10) Wenger RH Cellular adaptation to hypoxia: O-2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O-2-regulated gene expression | 0 | 117 |
| 137 | 1 | 22 | 11 2002 FEBS LETTERS 530(1-3):186-190 Saarikoski ST; Rivera SP; Hankinson O Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia | 1 | 4 |
| 138 | 1 | 125 | 12 2002 FREE RADICAL BIOLOGY AND MEDICINE 33(9):1231-1242 Michiels C; Minet E; Mottet D; Raes M Regulation of gene expression by oxygen: NF-kappa B and HIF-1, two extremes | 0 | 11 |
| 139 | 1 | 4 | 14 2002 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 54(5):1299-1301 Brown JM; Le QT Tumor hypoxia is important in radiotherapy, but how should we measure it? | 0 | 2 |
| 140 | 1 | 26 | 16 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(26):23508-23514 Gradin K; Takasaki C; Fujii-Kuriyama Y; Sogawa K The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine | 10 | 13 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 141 | 1 | 80 | 18 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(33):29936-29944 Isaacs JS; Jung YJ; Mimnaugh EG; Martinez A; Cuttitta F; Neckers LM Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway | 19 | 53 |
| 142 | 1 | 19 | 19 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(36):32405-32408 Makino Y; Kanopka A; Wilson WJ; Tanaka H; Poellinger L Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3 alpha locus | 19 | 33 |
| 143 | 1 | 59 | 23 2002 JOURNAL OF EXPERIMENTAL BIOLOGY 205(23):3579-3586 Bickler PE; Donohoe PH Adaptive responses of vertebrate neurons to hypoxia | 0 | 7 |
| 144 | 1 | 50 | 24 2002 JOURNAL OF EXPERIMENTAL ZOOLOGY 294(1):17-29 Powell WH; Hahn ME Identification and functional characterization of hypoxia-inducible factor 2 alpha from the estuarine teleost, Fundulus heteroclitus: Interaction of HIF-2 alpha with two ARNT2 splice variants | 0 | 2 |
| 145 | 1 | 183 | 25 2002 JOURNAL OF MOLECULAR MEDICINE-JMM 80(9):562-575 Acker T; Plate KH A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology | 2 | 9 |
| 146 | 1 | 120 | 26 2002 JOURNAL OF MOLECULAR MEDICINE-JMM 80(11):703-714 Kim KR; Moon HE; Kim KW Hypoxia-induced angiogenesis in human hepatocellular carcinoma | 0 | 1 |
| 147 | 1 | 111 | 27 2002 MASS SPECTROMETRY REVIEWS 21(3):183-216 Gorman JJ; Wallis TP; Pitt JJ Protein disulfide bond determination by mass spectrometry | 0 | 8 |
| 148 | 1 | 57 | 29 2002 METHODS 28(2):259-266 Tang Y; Schmitt-Ott K; Qian KP; Kagiyama S; Phillips MI Vigilant vectors: adeno-associated virus with a biosensor to switch on amplified therapeutic genes in specific tissues in life-threatening diseases | 1 | 3 |
| 149 | 1 | 57 | 30 2002 MOLECULAR AND CELLULAR BIOLOGY 22(19):6842-6853 Lavista-Llanos S; Centanin L; Irisarri M; Russo DM; Gleadle JM; Bocca SN; Muzzopappa M; Ratcliffe PJ; Wappner P Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar | 11 | 23 |
| 150 | 1 | 39 | 32 2002 MOLECULES AND CELLS 14(1):9-15 Lee E; Yim S; Lee SK; Park H Two transactivation domains of hypoxia-inducible factor-1 alpha regulated by the MEK-1/p42/p44 MAPK pathway | 0 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 151 | 1 | 45 | 34 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(8):5271-5276 Dames SA; Martinez-Yamout M; De Guzman RN; Dyson HJ; Wright PE Structural basis for Hif-1 alpha/CBP recognition in the cellular hypoxic response | 31 | 45 |
| 152 | 1 | 42 | 35 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(8):5367-5372 Freedman SJ; Sun ZYJ; Poy F; Kung AL; Livingston DM; Wagner G; Eck MJ Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha | 35 | 58 |
| 153 | 1 | 70 | 36 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(14):9480-9485 Su H; Arakawa-Hoyt J; Kan YW Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model | 1 | 13 |
| 154 | 1 | 29 | 37 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10423-10428 Willam C; Masson N; Tian YM; Mahmood SA; Wilson MI; Bicknell R; Eckardt KU; Maxwell PH; Ratcliffe PJ; Pugh CW Peptide blockade of HIF alpha degradation modulates cellular metabolism and angiogenesis | 16 | 25 |
| 155 | 1 | 16 | 42 2002 SCIENCE 295(5556):807-808 Bruick RK; McKnight SL Transcription - Oxygen sensing gets a second wind | 14 | 28 |
| 156 | 1 | 37 | 46 2002 TRENDS IN MOLECULAR MEDICINE 8(4):S62-S67 Semenza GL HIF-1 and tumor progression: pathophysiology and therapeutics | 0 | 79 |
| 157 | 1 | 78 | 47 2002 TRENDS IN PHARMACOLOGICAL SCIENCES 23(12):576-582 Bikfalvi A; Bicknell R Recent advances in angiogenesis, anti-angiogenesis and vascular targeting | 0 | 19 |
| 158 | 1 | 44 | 48 2003 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 284(2):C439-C446 Zhou J; Fandrey J; Schumann J; Tiegs G; Brune B NO and TNF-alpha released from activated macrophages stabilize HIF-1 alpha in resting tubular LLC-PK1 cells | 0 | 7 |
| 159 | 1 | 90 | 52 2003 ANTIOXIDANTS & REDOX SIGNALING 5(1):123-132 Dulak J; Jozkowicz A Regulation of vascular endothelial growth factor synthesis by nitric oxide: Facts and controversies | 0 | 7 |
| 160 | 1 | 45 | 58 2003 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1626(1-3):10-18 Graven KK; Bellur D; Klahn BD; Lowrey SL; Amberger E HIF-2 alpha regulates glyceraldehyde-3-phosphate dehydrogenase expression in endothelial cells | 1 | 4 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 161 | 1 | 130 | 59 2003 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1619(2):113-124 Templeton DM; Liu Y Genetic regulation of cell function in response to iron overload or chelation | 0 | 6 |
| 162 | 1 | 61 | 63 2003 CANCER CELL 3(1):75-88 Mack FA; Rathmell WK; Arsham AM; Gnarra J; Keith B; Simon MC Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth | 6 | 16 |
| 163 | 1 | 32 | 68 2003 CHEMORECEPTION: FROM CELLULAR SIGNALLING TO FUNCTIONAL PLASTICITY 536:65-73 Ortega-Saenz P; Garcia-Fernandez M; Pardal R; Alvarez E; Lopez-Barneo J Studies on glomus cell sensitivity to hypoxia in carotid body slices | 0 | 1 |
| 164 | 1 | 134 | 70 2003 CLINICAL & EXPERIMENTAL METASTASIS 20(3):237-250 Subarsky P; Hill RP The hypoxic tumour microenvironment and metastatic progression | 0 | 12 |
| 165 | 1 | 43 | 71 2003 CLINICAL CANCER RESEARCH 9(1):433-440 Park JH; Kim TY; Jong HS; Kim TY; Chun YS; Park JW; Lee CT; Jung HC; Kim NK; Bang YJ Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1 alpha in gastric cancer cells | 1 | 2 |
| 166 | 1 | 50 | 78 2003 CURRENT OPINION IN NEUROBIOLOGY 13(4):493-499 Lopez-Barneo J Oxygen and glucose sensing by carotid body glomus cells | 0 | 4 |
| 167 | 1 | 52 | 79 2003 EMBO JOURNAL 22(8):1857-1867 Li ZB; Wang DK; Na X; Schoen SR; Messing EM; Wu G The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1 alpha transcriptional activity | 3 | 5 |
| 168 | 1 | 60 | 83 2003 FASEB JOURNAL 17(2) Linden T; Katschinski DM; Eckhardt K; Scheid A; Pagel H; Wenger RH The antimycotic ciclopirox olamine induces HIF-1 alpha stability, VEGF expression, and angiogenesis | 0 | 0 |
| 169 | 1 | 36 | 85 2003 FASEB JOURNAL 17(15) Moon EJ; Jeong CH; Jeong JW; Kim KR; Yu DY; Murakami S; Kim CW; Kim KW Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1 alpha | 0 | 0 |
| 170 | 1 | 30 | 87 2003 FEBS LETTERS 554(3):264-270 Minchenko O; Opentanova I; Caro J Hypoxic regulation of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene family (PFKFB-1-4) expression in vivo | 0 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 171 | 1 | 39 | 92 2003 HISTOCHEMISTRY AND CELL BIOLOGY 120(5):343-352 Baby SM; Roy A; Mokashi AM; Lahiri S Effects of hypoxia and intracellular iron chelation on hypoxia-inducible factor-1 alpha and -1 beta in the rat carotid body and glomus cells | 1 | 3 |
| 172 | 1 | 23 | 99 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(18):15911-15916 Yuan Y; Hilliard G; Ferguson T; Millhorn DE Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha | 3 | 19 |
| 173 | 1 | 34 | 101 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(22):20235-20239 Wright G; Higgin JJ; Raines RT; Steenbergen C; Murphy E Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes | 2 | 3 |
| 174 | 1 | 59 | 102 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(25):22316-22324 Del Toro R; Levitsky KL; Lopez-Barneo J; Chiara MD Induction of T-type calcium channel gene expression by chronic hypoxia | 0 | 5 |
| 175 | 1 | 58 | 105 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(35):33384-33391 Kodama T; Shimizu N; Yoshikawa N; Makino Y; Ouchida R; Okamoto K; Hisada T; Nakamura H; Morimoto C; Tanaka H Role of the glucocorticoid receptor for regulation of hypoxia-dependent gene expression | 0 | 0 |
| 176 | 1 | 63 | 106 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(38):35878-35888 Lees MJ; Peet DJ; Whitelaw ML Defining the role for XAP2 in stabilization of the dioxin receptor | 0 | 2 |
| 177 | 1 | 49 | 109 2003 JOURNAL OF CELL SCIENCE 116(11):2247-2260 Turcotte S; Desrosiers RR; Beliveau R HIF-1 alpha mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma | 2 | 5 |
| 178 | 1 | 50 | 111 2003 JOURNAL OF CLINICAL INVESTIGATION 111(5):571-574 Soberman RJ The expanding network of redox signaling: new observations, complexities, and perspectives | 0 | 8 |
| 179 | 1 | 70 | 113 2003 JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION 26(9):832-837 Jelkmann W Erythropoietin | 0 | 0 |
| 180 | 1 | 46 | 114 2003 JOURNAL OF IMMUNOLOGY 171(12):6534-6540 Makino Y; Nakamura H; Ikeda E; Ohnuma K; Yamauchi K; Yabe Y; Poellinger L; Okada Y; Morimoto C; Tanaka H Hypoxia-inducible factor regulates survival of antigen receptor-driven T cells | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 181 | 1 | 18 | 115 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(16):4710-4711 Kinzie SD; Thevis M; Ngo K; Whitelegge J; Loo JA; Abu-Omar MM Posttranslational hydroxylation of human phenylalanine hydroxylase is a novel example of enzyme self-repair within the second coordination sphere of catalytic iron | 0 | 2 |
| 182 | 1 | 42 | 118 2003 MOLECULAR AND CELLULAR BIOLOGY 23(1):359-369 Goda N; Ryan HE; Khadivi B; McNulty W; Rickert RC; Johnson RS Hypoxia-inducible factor 1 alpha is essential for cell cycle arrest during hypoxia | 6 | 24 |
| 183 | 1 | 40 | 131 2003 NEOPLASMA 50(1):13-21 Chrastina A; Pastorekova S; Pastorek J Immunotargeting of human cervical carcinoma xenograft expressing CA IX tumor-associated antigen by I-125-labeled M75 monoclonal antibody | 0 | 2 |
| 184 | 1 | 55 | 132 2003 PLACENTA 24(2-3):199-208 Rajakumar A; Doty K; Daftary A; Harger G; Conrad KP Impaired oxygen-dependent reduction of HIF-1 alpha and -2 alpha proteins in pre-eclamptic placentae | 4 | 7 |
| 185 | 1 | 21 | 134 2003 RAPID COMMUNICATIONS IN MASS SPECTROMETRY 17(5):371-376 Hirota J; Satomi Y; Yoshikawa K; Takao T epsilon-N,N,N-Trimethyllysine-specific ions in matrix-assisted laser desorption/ionization-tandem mass spectrometry | 0 | 2 |
| 186 | 1 | 53 | 140 2003 THROMBOSIS AND HAEMOSTASIS 89(4):666-673 Kietzmann T; Jungermann K; Gorlach A Regulation of the hypoxia-dependent plasminogen activator inhibitor I expression by MAP kinases | 0 | 4 |
| 187 | 1 | 21 | 154 2004 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1691(1):17-22 Daly EB; Wind T; Jiang XM; Sun L; Hogg PJ Secretion of phosphoglycerate kinase from tumour cells is controlled by oxygen-sensing hydroxylases | 0 | 0 |
| 188 | 1 | 34 | 158 2004 CANCER RESEARCH 64(2):456-462 Datta K; Li JP; Bhattacharya R; Gasparian L; Wang EF; Mukhopadhyay D Protein kinase C zeta transactivates hypoxia-inducible factor alpha by promoting its association with p300 in renal cancer | 1 | 2 |
| 189 | 1 | 51 | 159 2004 CANCER RESEARCH 64(5):1765-1772 Mizukami Y; Li JN; Zhang XB; Zimmer MA; Iliopoulos O; Chung DC Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer | 0 | 0 |
| 190 | 1 | 278 | 174 2004 FREE RADICAL BIOLOGY AND MEDICINE 36(6):718-744 Kinnula VL; Crapo JD Superoxide dismutases in malignant cells and human tumors | 1 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 191 | 1 | 52 | 175 2004 FREE RADICAL BIOLOGY AND MEDICINE 36(10):1279-1288 Goyal P; Weissmann N; Grimminger F; Hegel C; Bader L; Rose F; Fink L; Ghofrani HA; Schermuly RT; Schmidt HHHW; Seeger W; Hanze J Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxiainducible factor 1 via increase in reactive oxygen species | 0 | 0 |
| 192 | 1 | 65 | 176 2004 INTERNATIONAL JOURNAL OF CANCER 111(1):43-50 Swinson DEB; Jones JL; Cox G; Richardson D; Harris AL; O'Byrne KJ Hypoxia-inducible factor-1 alpha in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways | 0 | 0 |
| 193 | 1 | 52 | 177 2004 JOURNAL OF APPLIED PHYSIOLOGY 96(3):1173-1177 Semenza GL O-2-regulated gene expression: transcriptional control of cardiorespiratory physiology by HIF-1 | 1 | 1 |
| 194 | 1 | 27 | 190 2004 OXYGEN SENSING 381:133-+ Roy S; Khanna S; Sen CK Perceived hyperoxia: Oxygen-regulated signal transduction pathways in the heart | 0 | 0 |
| 195 | 1 | 45 | 193 2004 PEDIATRIC RESEARCH 55(3):385-394 Wang XH; Deng JX; Boyle DW; Zhong J; Lee WH Potential role of IGF-I in hypoxia tolerance using a rat hypoxic-ischemic model: Activation of hypoxia-inducible factor 1 alpha | 0 | 0 |
| 196 | 1 | 40 | 194 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(12):4302-4307 Liu Q; Berchner-Pfannschmidt U; Moller U; Brecht M; Wotzlaw C; Acker H; Jungermann K; Kietzmann T A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression | 2 | 2 |
| 197 | 1 | 22 | 198 2004 THORAX 59(2):90-92 Walmsley SR; Sheares KKK; Sobolewski A; Morrell NW; Chilvers ER New insights into oxygen sensing at a cellular level | 0 | 0 |
| 198 | 1 | 16 | 199 2004 TOXICOLOGY AND APPLIED PHARMACOLOGY 196(3):404-409 Zhao JH; Chen HB; Davidson T; Kluz T; Zhang QW; Costa M Nickel-induced 1,4-alpha-glucan branching enzyme 1 up-regulation via the hypoxic signaling pathway | 0 | 0 |
| 199 | 0 | 28 | 43 2002 SCIENCE 295(5556):858-861 Lando D; Peet DJ; Whelan DA; Gorman JJ; Whitelaw ML Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch | 198 | 198 |
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