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Nodes: 141,
Authors: 523,
Journals: 55,
Outer References: 4251,
Words: 603
Collection span: 2003 - 2005
View: Overview. Sorted by journal name.
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| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
|---|---|---|---|---|---|
| 101 | 9 | 35 | 132 2005 JOURNAL OF NEUROCHEMISTRY 92 (5): 1010-1020 Hansson EM; Stromberg K; Bergstedt S; Yu G; Naslund J; et al. Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch | 0 | 0 |
| 102 | 2 | 43 | 133 2005 JOURNAL OF NEUROCHEMISTRY 92 (5): 1158-1169 Brunkan AL; Martinez M; Wang J; Walker ES; Goate AM A domain at the C-terminus of PS1 is required for presenilinase and gamma-secretase activities | 1 | 1 |
| 103 | 21 | 282 | 134 2005 JOURNAL OF NEUROCHEMISTRY 93 (4): 769-792 Brunkan AL; Goate AM Presenilin function and gamma-secretase activity | 0 | 0 |
| 104 | 1 | 41 | 16 2003 JOURNAL OF NEUROSCIENCE 23 (27): 9097-9106 Lilliehook C; Bozdagi O; Yao J; Gomez-Ramirez M; Zaidi NF; et al. Altered A beta formation and long-term potentiation in a calsenilin knock-out | 0 | 9 |
| 105 | 12 | 36 | 135 2005 JOURNAL OF NEUROSCIENCE 25 (1): 192-198 Ma GJ; Li T; Price DL; Wong PC APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development | 1 | 1 |
| 106 | 1 | 74 | 17 2003 JOURNAL OF NEUROSCIENCE RESEARCH 74 (3): 353-360 Kimberly WT; Wolfe MS Identity and function of gamma-secretase | 4 | 15 |
| 107 | 1 | 112 | 18 2003 JOURNAL OF NEUROSCIENCE RESEARCH 74 (3): 361-369 Wilson CA; Doms RW; Lee VMY Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular A beta production | 3 | 5 |
| 108 | 13 | 113 | 84 2004 JOURNAL OF NEUROSCIENCE RESEARCH 77 (3): 309-322 Periz G; Fortini ME Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2 | 5 | 6 |
| 109 | 2 | 113 | 136 2005 JOURNAL OF NEUROSCIENCE RESEARCH 80 (2): 151-159 Kerr ML; Small DH Cytoplasmic domain of the beta-amyloid protein precursor of Alzheimer's disease: Function, regulation of proteolysis, and implications for drug development | 0 | 0 |
| 110 | 1 | 44 | 85 2004 JOURNAL OF VIROLOGY 78 (21): 11766-11777 Ogino T; Fukuda H; Imajoh-Ohmi S; Kohara M; Nomoto A Membrane binding properties and terminal residues of the mature hepatitis C virus capsid protein in insect cells | 0 | 0 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 111 | 1 | 77 | 86 2004 MOLECULAR AND CELLULAR BIOLOGY 24 (1): 454-464 Wilhelmsen K; van der Geer P Phorbol 12-myristate 13-acetate-induced release of the colony-stimulating factor 1 receptor cytoplasmic domain into the cytosol involves two separate cleavage events | 1 | 5 |
| 112 | 1 | 51 | 19 2003 MOLECULAR AND CELLULAR NEUROSCIENCE 24 (3): 646-655 Harrison SM; Harper AJ; Hawkins J; Duddy G; Grau E; et al. BACE1 (beta-secretase) transgenic neurochernical deficits ind knockout mice: identification of and behavioral changes | 2 | 7 |
| 113 | 8 | 68 | 137 2005 MOLECULAR AND CELLULAR NEUROSCIENCE 29 (1): 65-73 Brunkan AL; Martinez M; Walker ES; Goate AM Presenilin endoproteolysis is an intrarnolecular cleavage | 0 | 0 |
| 114 | 3 | 51 | 87 2004 MOLECULAR MEMBRANE BIOLOGY 21 (6): 373-383 Harnasch M; Grau S; Behrends C; Dove SL; Hochschild A; et al. Characterization of presenilin-amyloid precursor interaction using bacterial expression and two-hybrid systems for human membrane proteins | 0 | 1 |
| 115 | 3 | 13 | 88 2004 MOLECULAR PSYCHIATRY 9 (1): 8-10 Iwatsubo T Assembly and activation of the gamma-secretase complex: roles of presenilin cofactors | 2 | 2 |
| 116 | 1 | 46 | 89 2004 MOLECULAR PSYCHIATRY 9 (6): 594-602 Verdile G; Groth D; Mathews PM; St George-Hyslop P; Fraser PE; et al. Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells | 0 | 0 |
| 117 | 1 | 206 | 90 2004 MOLECULAR PSYCHIATRY 9 (7): 664-683 Gotz J; Streffer JR; David D; Schild A; Hoerndli F; et al. Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy | 1 | 7 |
| 118 | 1 | 48 | 91 2004 NATURE BIOTECHNOLOGY 22 (6): 724-731 Schmitt-Ulms G; Hansen K; Liu JL; Cowdrey C; Yang J; et al. Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues | 0 | 2 |
| 119 | 0 | 15 | 20 2003 NATURE CELL BIOLOGY 5 (5): 486-488 Edbauer D; Winkler E; Regula JT; Pesold B; Steiner H; et al. Reconstitution of gamma-secretase activity | 140 | 140 |
| 120 | 1 | 104 | 92 2004 NATURE CELL BIOLOGY 6 (11): 1054-1061 Selkoe DJ Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases | 0 | 0 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 121 | 2 | 36 | 93 2004 NATURE MEDICINE 10 (9): 959-965 He WX; Lu YF; Qahwash I; Hu XY; Chang AS; et al. Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation | 0 | 2 |
| 122 | 1 | 107 | 94 2004 NATURE REVIEWS MOLECULAR CELL BIOLOGY 5 (3): 188-197 Freeman M Proteolysis within the membrane: Rhomboids revealed | 1 | 7 |
| 123 | 2 | 106 | 95 2004 NATURE REVIEWS NEUROSCIENCE : S2-S9 Bossy-Wetzel E; Schwarzenbacher R; Lipton SA Molecular pathways to neurodegeneration | 0 | 0 |
| 124 | 4 | 111 | 96 2004 NATURE REVIEWS NEUROSCIENCE : S26-S33 Koo EH; Kopan R Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration | 0 | 0 |
| 125 | 2 | 95 | 97 2004 NATURE REVIEWS NEUROSCIENCE 5 (9): 677-685 Citron M Strategies for disease modification in Alzheimer's disease | 1 | 10 |
| 126 | 2 | 137 | 138 2005 NEUROBIOLOGY OF AGING 26 (3): 373-382 Nixon RA Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases | 0 | 0 |
| 127 | 1 | 57 | 98 2004 NEUROBIOLOGY OF DISEASE 17 (2): 205-218 Hecimovic S; Wang J; Dolios G; Martinez M; Wang R; et al. Mutations in APP have independent effects on A beta and CTF gamma generation | 3 | 3 |
| 128 | 12 | 63 | 99 2004 NEUROBIOLOGY OF DISEASE 17 (2): 260-272 Hebert SS; Serneels L; Dejaegere T; Horre K; Dabrowski M; et al. Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity | 3 | 3 |
| 129 | 5 | 58 | 100 2004 NEUROSCIENCE 129 (3): 615-628 Siman R; Salidas S Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain | 0 | 0 |
| 130 | 3 | 54 | 101 2004 ONCOGENE 23 (42): 7076-7086 Saleh AZM; Fang AT; Arch AE; Neupane D; El Fiky A; et al. Regulated proteolysis of the IFNaR2 subunit of the interferon-alpha receptor | 0 | 1 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 131 | 1 | 127 | 102 2004 PHARMACOLOGICAL RESEARCH 50 (4): 397-409 Verdile G; Fuller S; Atwood CS; Laws SM; Gandy SE; et al. The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught? | 0 | 0 |
| 132 | 1 | 105 | 103 2004 PHARMACOLOGICAL RESEARCH 50 (4): 411-418 Thinakaran G; Parent AT Identification of the role of presenilins beyond Alzheimer's disease | 1 | 4 |
| 133 | 3 | 67 | 21 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (22): 13075-13080 Schroeter EH; Ilagan MXG; Brunkan AL; Hecimovic S; Li YM; et al. A presenilin dimer at the core of the gamma-secretase enzyme: Insights from parallel analysis of Notch 1 and APP proteolysis | 23 | 34 |
| 134 | 1 | 22 | 104 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (4): 905-906 Kim J; Schekman R The ins and outs of presenilin 1 membrane topology | 2 | 3 |
| 135 | 6 | 28 | 139 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (5): 1719-1724 Serneels L; Dejaegere T; Craessaerts K; Horre K; Jorissen E; et al. Differential contribution of the three Aph1 genes to gamma-secretase activity in vivoi | 2 | 2 |
| 136 | 3 | 34 | 140 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (6): 1883-1888 Urban S; Wolfe MS Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity | 0 | 1 |
| 137 | 2 | 31 | 141 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (9): 3230-3235 Kornilova AY; Bihel F; Das C; Wolfe MS The initial substrate-binding site of gamma-secretase is located on presenilin near the active site | 0 | 0 |
| 138 | 2 | 204 | 22 2003 REVIEWS IN THE NEUROSCIENCES 14 (4): 317-341 Stein TD; Johnson JA Genetic programming by the proteolytic fragments of the amyloid precursor protein: Somewhere between confusion and clarity | 0 | 4 |
| 139 | 3 | 104 | 23 2003 SCIENCE 302 (5646): 814-818 Aguzzi A; Haass C Games played by rogue proteins in prion disorders and Alzheimer's disease | 2 | 23 |
| 140 | 9 | 73 | 105 2004 SCIENCE 305 (5687): 1119-1123 Wolfe MS; Kopan R Intramembrane proteotysis: Theme and variations | 4 | 11 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 141 | 1 | 110 | 106 2004 SEMINARS IN CANCER BIOLOGY 14 (5): 320-328 Hansson EM; Lendahl U; Chapman G Notch signaling in development and disease | 1 | 5 |
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