Missing Links? Citation Matrix Graphs Glossary  HistCite Guide  About
Fri Jun 3 10:17:24 2005

Reconstitution of gamma-secretase activity
Edbauer D, Winkler E, Regula JT, Pesold B, Steiner H, Haass C
NATURE CELL BIOLOGY 5 (5): 486-488 MAY 2003

Nodes: 141, Authors: 523, Journals: 55, Outer References: 4251, Words: 603
Collection span: 2003 - 2005
View: Overview. Sorted by date.
Page 1 of 2: [  1  2 ]

#LCRNCRNode / Date / Journal / AuthorLCSGCS
101520 2003 MAY [15] NATURE CELL BIOLOGY 5 (5): 486-488
Edbauer D; Winkler E; Regula JT; Pesold B; Steiner H; et al.
Reconstitution of gamma-secretase activity
140140
212414 2003 MAY 26 JOURNAL OF CELL BIOLOGY 161 (4): 685-690
Hu Y; Fortini ME
Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex
3744
3220422 2003 [JUN 30] REVIEWS IN THE NEUROSCIENCES 14 (4): 317-341
Stein TD; Johnson JA
Genetic programming by the proteolytic fragments of the amyloid precursor protein: Somewhere between confusion and clarity
04
41577 2003 JUL 4 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (27): 24277-24284
Farmery MR; Tjernberg LO; Pursglove SE; Bergman A; Winblad B; et al.
Partial purification and characterization of gamma-secretase from post-mortem human brain
1520
516915 2003 JUL 15 JOURNAL OF CELL SCIENCE 116 (14): 2839-2844
Xia WM; Wolfe MS
Intramembrane proteolysis by presenilin and presenilin-like proteases
511
61231 2003 AUG [15] ANNALS OF NEUROLOGY 54 (2): 143-144
Hardy J
Alzheimer's disease: Genetic evidence points to a single pathogenesis
04
71598 2003 AUG 15 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (33): 30748-30754
Weggen S; Eriksen JL; Sagi SA; Pietrzik CU; Golde TE; et al.
A beta 42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain
210
81254 2003 AUG 28 FEBS LETTERS 550 (1-3): 30-34
Hebert SS; Godin C; Levesque G
Oligomerization of human presenilin-1 fragments
23
91639 2003 SEP 5 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (36): 33992-34002
Kim SH; Ikeuchi T; Yu CJ; Sisodia SS
Regulated hyperaccumulation of presenilin-1 and the "gamma-secretase" complex - Evidence for differential intramembranous processing of transmembrane substrates
2125
1023310 2003 SEP 26 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (39): 37213-37222
LaVoie MJ; Fraering PC; Ostaszewski BL; Ye WJ; Kimberly WT; et al.
Assembly of the gamma-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin
3849
#LCRNCRNode / Date / Journal / AuthorLCSGCS
1114116 2003 OCT 8 JOURNAL OF NEUROSCIENCE 23 (27): 9097-9106
Lilliehook C; Bozdagi O; Yao J; Gomez-Ramirez M; Zaidi NF; et al.
Altered A beta formation and long-term potentiation in a calsenilin knock-out
09
121445 2003 OCT 15 HUMAN MOLECULAR GENETICS 12: R201-R206
Martoglio B; Golde TE
Intramembrane-cleaving aspartic proteases and disease: presenilins, signal peptide peptidase and their homologs
010
132626 2003 OCT 15 HUMAN MOLECULAR GENETICS 12 (20): 2669-2678
Guo M; Hong EJ; Fernandes J; Zipursky SL; Hay BA
A reporter for amyloid precursor protein gamma-secretase activity in Drosophila
24
1414411 2003 OCT 24 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (43): 42161-42169
Jung KM; Tan S; Landman N; Petrova K; Murray S; et al.
Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor
624
1536721 2003 OCT 28 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (22): 13075-13080
Schroeter EH; Ilagan MXG; Brunkan AL; Hecimovic S; Li YM; et al.
A presenilin dimer at the core of the gamma-secretase enzyme: Insights from parallel analysis of Notch 1 and APP proteolysis
2334
1624612 2003 OCT 31 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (44): 43284-43291
Morais VA; Crystal AS; Pijak DS; Carlin D; Costa J; et al.
The transmembrane domain region of nicastrin mediates direct interactions with APH-1 and the gamma-secretase complex
2023
17310423 2003 OCT 31 SCIENCE 302 (5646): 814-818
Aguzzi A; Haass C
Games played by rogue proteins in prion disorders and Alzheimer's disease
223
1817417 2003 NOV 1 JOURNAL OF NEUROSCIENCE RESEARCH 74 (3): 353-360
Kimberly WT; Wolfe MS
Identity and function of gamma-secretase
415
19111218 2003 NOV 1 JOURNAL OF NEUROSCIENCE RESEARCH 74 (3): 361-369
Wilson CA; Doms RW; Lee VMY
Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular A beta production
35
201713 2003 NOV [15] CURRENT OPINION IN RHEUMATOLOGY 15 (6): 737-744
Askanas V; Engel WK
Proposed pathogenetic cascade of inclusion-body myositis: importance of amyloid-beta, misfolded proteins, predisposing genes, and aging
08
#LCRNCRNode / Date / Journal / AuthorLCSGCS
2115119 2003 NOV [15] MOLECULAR AND CELLULAR NEUROSCIENCE 24 (3): 646-655
Harrison SM; Harper AJ; Hawkins J; Duddy G; Grau E; et al.
BACE1 (beta-secretase) transgenic neurochernical deficits ind knockout mice: identification of and behavioral changes
27
221602 2003 DEC 2 BIOCHEMISTRY 42 (47): 13977-13986
Wada S; Morishima-Kawashima M; Qi Y; Misono H; Shimada Y; et al.
gamma-secretase activity is present in rafts but is not cholesterol-dependent
28
2343413 2003 DEC 26 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (52): 52519-52523
Capell A; Kaether C; Edbauer D; Shirotani K; Merkl S; et al.
Nicastrin interacts with gamma-secretase complex components via the N-terminal part of its transmembrane domain
68
2455545 2004 JAN [15] EUROPEAN JOURNAL OF BIOCHEMISTRY 271 (2): 375-385
Culvenor JG; Ilaya NT; Ryan MT; Canterford L; Hoke DE; et al.
Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations
57
2517786 2004 JAN [15] MOLECULAR AND CELLULAR BIOLOGY 24 (1): 454-464
Wilhelmsen K; van der Geer P
Phorbol 12-myristate 13-acetate-induced release of the colony-stimulating factor 1 receptor cytoplasmic domain into the cytosol involves two separate cleavage events
15
2664825 2004 JAN 20 BIOCHEMISTRY 43 (2): 323-333
Fraering PC; LaVoie MJ; Ye WJ; Ostaszewski BL; Kimberly WT; et al.
Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex
1720
27122104 2004 JAN 27 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (4): 905-906
Kim J; Schekman R
The ins and outs of presenilin 1 membrane topology
23
2844352 2004 JAN 30 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (5): 3685-3693
Fortna RR; Crystal AS; Morais VA; Pijak DS; Lee VMY; et al.
Membrane topology and nicastrin-enhanced endoproteolysis of APH-1, a component of the gamma-secretase complex
1011
2953853 2004 FEB 6 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (6): 4144-4152
Lee SF; Shah S; Yu C; Wigley WC; Li H; et al.
A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gamma-secretase complex
912
3044842 2004 FEB 11 EMBO JOURNAL 23 (3): 483-488
Haass C
Take five - BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation
1530
#LCRNCRNode / Date / Journal / AuthorLCSGCS
31110334 2004 FEB [15] CELLULAR AND MOLECULAR LIFE SCIENCES 61 (3): 326-335
Johansson J; Weaver TE; Tjernberg LO
Proteolytic generation and aggregation of peptides from transmembrane regions: lung surfactant protein C and amyloid beta-peptide
03
32114451 2004 FEB [15] JOURNAL OF ALZHEIMERS DISEASE 6 (1): 53-65
Pasternak SH; Callahan JW; Mahuran DJ
The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: Reexamining the spatial paradox from a lysosomal perspective
13
3315776 2004 FEB [15] JOURNAL OF NEUROCHEMISTRY 88 (4): 869-877
Smith IF; Boyle JP; Green KN; Pearson HA; Peers C
Hypoxic remodelling of Ca2+ mobilization in type I cortical astrocytes: involvement of ROS and pro-amyloidogenic APP processing
03
34410336 2004 MAR [15] CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 7 (2): 169-178
Westlund B; Stilwell G; Sluder A
Invertebrate disease models in neurotherapeutic discovery
00
3517977 2004 MAR [15] JOURNAL OF NEUROCHEMISTRY 88 (5): 1140-1150
Pierrot N; Ghisdal P; Caumont AS; Octave JN
Intraneuronal amyloid-beta 1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death
02
36110794 2004 MAR [15] NATURE REVIEWS MOLECULAR CELL BIOLOGY 5 (3): 188-197
Freeman M
Proteolysis within the membrane: Rhomboids revealed
17
3775826 2004 MAR 30 BIOCHEMISTRY 43 (12): 3555-3563
Crystal AS; Morais VA; Fortna RR; Carlin D; Pierson TC; et al.
Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation
56
3823654 2004 APR 9 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (15): 15153-15160
Nyborg AC; Kornilova AY; Jansen K; Ladd TB; Wolfe MS; et al.
Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor
69
3913647 2004 APR [15] HUMAN MOLECULAR GENETICS 13: R123-R126
Singleton A; Myers A; Hardy J
The law of mass action applied to neurodegenerative disease: a hypothesis concerning the etiology and pathogenesis of complex diseases
012
4015978 2004 APR [15] JOURNAL OF NEUROCHEMISTRY 89 (1): 44-53
Laudon H; Mathews PM; Karlstrom H; Bergman A; Farmery MR; et al.
Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein
47
#LCRNCRNode / Date / Journal / AuthorLCSGCS
4113255 2004 APR 16 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (16): 16744-16753
Bergman A; Hansson EM; Pursglove SE; Farmery MR; Lannfelt L; et al.
Pen-2 is sequestered in the endoplasmic reticulum and subjected to ubiquitylation and proteasome-mediated degradation in the absence of presenilin
1013
4213832 2004 APR 19 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14 (8): 1935-1938
Esler WP; Das C; Wolfe MS
Probing pockets S2-S4 ' of the gamma-secretase active site with (hydroxyethyl)urea peptidomimeties
01
4314527 2004 MAY 25 BIOCHEMISTRY 43 (20): 6208-6218
Knappenberger KS; Tian GC; Ye XM; Sobotka-Briner C; Ghanekar SV; et al.
Mechanism of gamma-secretase cleavage activation: Is gamma-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop?
12
4464856 2004 MAY 28 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (22): 23255-23261
Prokop S; Shirotani K; Edbauer D; Haass C; Steiner H
Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complex
1010
4533657 2004 JUN 11 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (24): 25333-25338
Pitsi D; Octave JN
Presenilin 1 stabilizes the C-terminal fragment of the amyloid precursor protein independently of gamma-secretase activity
01
4613131 2004 JUN [15] BIOLOGICAL CHEMISTRY 385 (6): 481-485
Middendorp O; Luthi U; Hausch F; Barberis A
Searching for the most effective screening system to identify cell-active inhibitors of beta-secretase
01
4752838 2004 JUN [15] CURRENT OPINION IN NEUROBIOLOGY 14 (3): 379-383
Iwatsubo T
The gamma-secretase complex: machinery for intramembrane proteolysis
15
4813341 2004 JUN [15] DRUG NEWS & PERSPECTIVES 17 (5): 321-325
Tomita T; Iwatsubo T
The inhibition of gamma-secretase as a therapeutic approach to Alzheimer's disease
12
4964279 2004 JUN [15] JOURNAL OF NEUROCHEMISTRY 89 (6): 1520-1527
Shirotani K; Edbauer D; Kostka M; Steiner H; Haass C
Immature nicastrin stabilizes APH-1 independent of PEN-2 and presenilin: identification of nicastrin mutants that selectively interact with APH-1
88
5014689 2004 JUN [15] MOLECULAR PSYCHIATRY 9 (6): 594-602
Verdile G; Groth D; Mathews PM; St George-Hyslop P; Fraser PE; et al.
Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells
00
#LCRNCRNode / Date / Journal / AuthorLCSGCS
5114891 2004 JUN [15] NATURE BIOTECHNOLOGY 22 (6): 724-731
Schmitt-Ulms G; Hansen K; Liu JL; Cowdrey C; Yang J; et al.
Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues
02
5228424 2004 [JUN 30] ANNUAL REVIEW OF GENETICS 38: 709-724
Ehrmann M; Clausen T
Proteolysis as aregulatory mechanism
12
53129533 2004 [JUN 30] CELL BIOCHEMISTRY AND BIOPHYSICS 41 (1): 139-178
Makarova A; Williams SE; Strickland DK
Proteases and lipoprotein receptors in Alzheimer's disease
00
5431388 2004 [JUN 30] MOLECULAR PSYCHIATRY 9 (1): 8-10
Iwatsubo T
Assembly and activation of the gamma-secretase complex: roles of presenilin cofactors
22
55558100 2004 [JUN 30] NEUROSCIENCE 129 (3): 615-628
Siman R; Salidas S
Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain
00
5615948 2004 JUL 1 HUMAN MOLECULAR GENETICS 13 (13): 1321-1331
Tournoy J; Bossuyt X; Snellinx A; Regent M; Garmyn M; et al.
Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice
13
5717558 2004 JUL 9 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (28): 29469-29477
Li AM; Dong JX; Harris DA
Cell surface expression of the prion protein in yeast does not alter copper utilization phenotypes
01
58126035 2004 JUL [15] CLINICAL GENETICS 66 (1): 1-16
Wellington CL
Cholesterol at the crossroads: Alzheimer's disease and lipid metabolism
00
59120690 2004 JUL [15] MOLECULAR PSYCHIATRY 9 (7): 664-683
Gotz J; Streffer JR; David D; Schild A; Hoerndli F; et al.
Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy
17
60210695 2004 JUL [15] NATURE REVIEWS NEUROSCIENCE : S2-S9
Bossy-Wetzel E; Schwarzenbacher R; Lipton SA
Molecular pathways to neurodegeneration
00
#LCRNCRNode / Date / Journal / AuthorLCSGCS
61411196 2004 JUL [15] NATURE REVIEWS NEUROSCIENCE : S26-S33
Koo EH; Kopan R
Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration
00
621311384 2004 AUG 1 JOURNAL OF NEUROSCIENCE RESEARCH 77 (3): 309-322
Periz G; Fortini ME
Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2
56
6346928 2004 AUG 3 BIOCHEMISTRY 43 (30): 9774-9789
Fraering PC; Ye WJ; Strub JM; Dolios G; LaVoie MJ; et al.
Purification and characterization of the human gamma-secretase complex
46
6426443 2004 AUG 4 EMBO JOURNAL 23 (15): 3041-3050
Haffner C; Frauli M; Topp S; Irmler M; Hofmann K; et al.
Nicalin and its binding partner Nomo are novel Nodal signaling antagonists
00
6526274 2004 AUG 15 JOURNAL OF CELL SCIENCE 117 (18): 4099-4111
Gowrishankar K; Zeidler MG; Vincenz C
Release of a membrane-bound death domain by gamma-secretase processing of the p75(NTR) homolog NRADD
11
6615480 2004 AUG [15] JOURNAL OF NEUROCHEMISTRY 90 (3): 712-723
van Dijk R; Fischer DF; Sluijs JA; Sonnemans MAF; Hobo B; et al.
Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta 40
00
67973105 2004 AUG 20 SCIENCE 305 (5687): 1119-1123
Wolfe MS; Kopan R
Intramembrane proteotysis: Theme and variations
411
6816475 2004 SEP 1 JOURNAL OF CELL SCIENCE 117 (19): 4435-4448
von Rotz RC; Kohli BM; Bosset J; Meier M; Suzuki T; et al.
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor
14
6993759 2004 SEP 3 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (36): 37311-37315
Edbauer D; Kaether C; Steiner H; Haass C
Co-expression of nicastrin and presenilin rescues a loss of function mutant of APH-1
11
7044060 2004 SEP 3 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (36): 38040-38046
Hayashi I; Urano Y; Fukuda R; Isoo N; Kodama T; et al.
Selective reconstitution and recovery of functional gamma-secretase complex on budded baculovirus particles
23
#LCRNCRNode / Date / Journal / AuthorLCSGCS
7114230 2004 SEP 6 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1674 (1): 29-39
Middendorp O; Ortler C; Neumann U; Paganetti P; Luthi U; et al.
Yeast growth selection system for the identification of cell-active inhibitors of beta-secretase
00
72711737 2004 SEP [15] CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 7 (5): 709-719
Harrison T; Churcher I; Beher D
gamma-Secretase as a target for drug intervention in Alzheimer's disease
13
7323781 2004 SEP [15] JOURNAL OF NEUROCHEMISTRY 90 (6): 1312-1320
Wrigley JDJ; Nunn EJ; Nyabi O; Clarke EE; Hunt P; et al.
Conserved residues within the putative active site of gamma-secretase differentially influence enzyme activity and inhibitor binding
55
74106282 2004 SEP [15] JOURNAL OF NEUROCHEMISTRY 90 (6): 1402-1413
Shiraishi H; Sai X; Wang HQ; Maeda Y; Kurono Y; et al.
PEN-2 enhances gamma-cleavage after presenilin heterodimer formation
00
7523693 2004 SEP [15] NATURE MEDICINE 10 (9): 959-965
He WX; Lu YF; Qahwash I; Hu XY; Chang AS; et al.
Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation
02
7629597 2004 SEP [15] NATURE REVIEWS NEUROSCIENCE 5 (9): 677-685
Citron M
Strategies for disease modification in Alzheimer's disease
110
77354101 2004 SEP 16 ONCOGENE 23 (42): 7076-7086
Saleh AZM; Fang AT; Arch AE; Neupane D; El Fiky A; et al.
Regulated proteolysis of the IFNaR2 subunit of the interferon-alpha receptor
01
7825561 2004 SEP 17 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (38): 39710-39717
Schmechel A; Strauss M; Schlicksupp A; Pipkorn R; Haass C; et al.
Human BACE forms dimers and colocalizes with APP
22
7987562 2004 SEP 24 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (39): 40560-40566
Wang H; Luo WJ; Zhang YW; Li YM; Thinakaran G; et al.
Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components
13
80105663 2004 OCT 1 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (40): 41340-41345
Shirotani K; Edbauer D; Prokop S; Haass C; Steiner H
Identification of distinct gamma-secretase complexes with different APH-1 variants
78
#LCRNCRNode / Date / Journal / AuthorLCSGCS
8112664 2004 OCT 8 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (41): 43046-43051
Shen JS; Prywes R
Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6
00
8243665 2004 OCT 8 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (41): 43148-43156
Nyborg AC; Jansen K; Ladd TB; Fauq A; Golde TE
A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin
01
8335839 2004 OCT [15] CURRENT OPINION IN NEUROBIOLOGY 14 (5): 582-588
Wilquet V; De Strooper B
Amyloid-beta precursor protein processing in neurodegeneration
01
84522240 2004 OCT [15] CYTOKINE & GROWTH FACTOR REVIEWS 15 (5): 337-351
Landman N; Kim TW
Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling
01
8544866 2004 OCT 15 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (42): 43419-43426
Beher D; Clarke EE; Wrigley JDJ; Martin ACL; Nadin A; et al.
Selected non-steroidal anti-inflammatory drugs and their derivatives target gamma-secretase at a novel site - Evidence for an allosteric mechanism
13
8665183 2004 OCT [15] JOURNAL OF NEUROCHEMISTRY 91 (1): 230-237
Ilaya NT; Evin G; Masters CL; Culvenor JG
Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle
00
871127102 2004 OCT [15] PHARMACOLOGICAL RESEARCH 50 (4): 397-409
Verdile G; Fuller S; Atwood CS; Laws SM; Gandy SE; et al.
The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught?
00
881105103 2004 OCT [15] PHARMACOLOGICAL RESEARCH 50 (4): 411-418
Thinakaran G; Parent AT
Identification of the role of presenilins beyond Alzheimer's disease
14
891110106 2004 OCT [15] SEMINARS IN CANCER BIOLOGY 14 (5): 320-328
Hansson EM; Lendahl U; Chapman G
Notch signaling in development and disease
15
9012929 2004 OCT 26 BIOCHEMISTRY 43 (42): 13532-13540
Funamoto S; Morshima-Kawashima M; Tanimura Y; Hirotani N; Saido TC; et al.
Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42
01
#LCRNCRNode / Date / Journal / AuthorLCSGCS
9132967 2004 NOV 5 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (45): 46455-46463
Hasegawa H; Sanjo N; Chen FS; Gu YJ; Shier C; et al.
Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes
33
9213446 2004 NOV [15] EUROPEAN JOURNAL OF BIOCHEMISTRY 271 (22): 4485-4494
Pastorcic M; Das HK
Alternative initiation of transcription of the human presenilin 1 gene in SH-SY5Y and SK-N-SH cells - The role of Ets factors in the regulation of presenilin 1
00
93212550 2004 NOV [15] INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 22 (7): 453-465
Gotz J; Schild A; Hoerndli F; Pennanen L
Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models
02
9414485 2004 NOV [15] JOURNAL OF VIROLOGY 78 (21): 11766-11777
Ogino T; Fukuda H; Imajoh-Ohmi S; Kohara M; Nomoto A
Membrane binding properties and terminal residues of the mature hepatitis C virus capsid protein in insect cells
00
9535187 2004 NOV [15] MOLECULAR MEMBRANE BIOLOGY 21 (6): 373-383
Harnasch M; Grau S; Behrends C; Dove SL; Hochschild A; et al.
Characterization of presenilin-amyloid precursor interaction using bacterial expression and two-hybrid systems for human membrane proteins
01
96110492 2004 NOV [15] NATURE CELL BIOLOGY 6 (11): 1054-1061
Selkoe DJ
Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases
00
9715798 2004 NOV [15] NEUROBIOLOGY OF DISEASE 17 (2): 205-218
Hecimovic S; Wang J; Dolios G; Martinez M; Wang R; et al.
Mutations in APP have independent effects on A beta and CTF gamma generation
33
98126399 2004 NOV [15] NEUROBIOLOGY OF DISEASE 17 (2): 260-272
Hebert SS; Serneels L; Dejaegere T; Horre K; Dabrowski M; et al.
Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity
33
9952668 2004 NOV 19 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (47): 48615-48619
Kim SH; Yin YI; Li YM; Sisodia SS
Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway
34
10015569 2004 NOV 19 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (47): 49105-49112
Ghersi E; Noviello C; D'Adamio L
Amyloid-beta protein precursor (A beta PP) intracellular domain-associated protein-1 proteins bind to A beta PP and modulate its processing in an isoform-specific manner
00

Page 1 of 2: [  1  2 ]
Generated by: HistCite 2005.05.14