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Nodes: 141,
Authors: 523,
Journals: 55,
Outer References: 4251,
Words: 603
Collection span: 2003 - 2005
View: Overview. Sorted by LCR.
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| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
|---|---|---|---|---|---|
| 101 | 1 | 29 | 29 2004 BIOCHEMISTRY 43 (42): 13532-13540 Funamoto S; Morshima-Kawashima M; Tanimura Y; Hirotani N; Saido TC; et al. Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42 | 0 | 1 |
| 102 | 1 | 42 | 30 2004 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1674 (1): 29-39 Middendorp O; Ortler C; Neumann U; Paganetti P; Luthi U; et al. Yeast growth selection system for the identification of cell-active inhibitors of beta-secretase | 0 | 0 |
| 103 | 1 | 31 | 31 2004 BIOLOGICAL CHEMISTRY 385 (6): 481-485 Middendorp O; Luthi U; Hausch F; Barberis A Searching for the most effective screening system to identify cell-active inhibitors of beta-secretase | 0 | 1 |
| 104 | 1 | 38 | 32 2004 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14 (8): 1935-1938 Esler WP; Das C; Wolfe MS Probing pockets S2-S4 ' of the gamma-secretase active site with (hydroxyethyl)urea peptidomimeties | 0 | 1 |
| 105 | 1 | 295 | 33 2004 CELL BIOCHEMISTRY AND BIOPHYSICS 41 (1): 139-178 Makarova A; Williams SE; Strickland DK Proteases and lipoprotein receptors in Alzheimer's disease | 0 | 0 |
| 106 | 1 | 103 | 34 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61 (3): 326-335 Johansson J; Weaver TE; Tjernberg LO Proteolytic generation and aggregation of peptides from transmembrane regions: lung surfactant protein C and amyloid beta-peptide | 0 | 3 |
| 107 | 1 | 260 | 35 2004 CLINICAL GENETICS 66 (1): 1-16 Wellington CL Cholesterol at the crossroads: Alzheimer's disease and lipid metabolism | 0 | 0 |
| 108 | 1 | 33 | 41 2004 DRUG NEWS & PERSPECTIVES 17 (5): 321-325 Tomita T; Iwatsubo T The inhibition of gamma-secretase as a therapeutic approach to Alzheimer's disease | 1 | 2 |
| 109 | 1 | 34 | 46 2004 EUROPEAN JOURNAL OF BIOCHEMISTRY 271 (22): 4485-4494 Pastorcic M; Das HK Alternative initiation of transcription of the human presenilin 1 gene in SH-SY5Y and SK-N-SH cells - The role of Ets factors in the regulation of presenilin 1 | 0 | 0 |
| 110 | 1 | 36 | 47 2004 HUMAN MOLECULAR GENETICS 13: R123-R126 Singleton A; Myers A; Hardy J The law of mass action applied to neurodegenerative disease: a hypothesis concerning the etiology and pathogenesis of complex diseases | 0 | 12 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 111 | 1 | 59 | 48 2004 HUMAN MOLECULAR GENETICS 13 (13): 1321-1331 Tournoy J; Bossuyt X; Snellinx A; Regent M; Garmyn M; et al. Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice | 1 | 3 |
| 112 | 1 | 144 | 51 2004 JOURNAL OF ALZHEIMERS DISEASE 6 (1): 53-65 Pasternak SH; Callahan JW; Mahuran DJ The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: Reexamining the spatial paradox from a lysosomal perspective | 1 | 3 |
| 113 | 1 | 32 | 55 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (16): 16744-16753 Bergman A; Hansson EM; Pursglove SE; Farmery MR; Lannfelt L; et al. Pen-2 is sequestered in the endoplasmic reticulum and subjected to ubiquitylation and proteasome-mediated degradation in the absence of presenilin | 10 | 13 |
| 114 | 1 | 75 | 58 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (28): 29469-29477 Li AM; Dong JX; Harris DA Cell surface expression of the prion protein in yeast does not alter copper utilization phenotypes | 0 | 1 |
| 115 | 1 | 26 | 64 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (41): 43046-43051 Shen JS; Prywes R Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6 | 0 | 0 |
| 116 | 1 | 55 | 69 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (47): 49105-49112 Ghersi E; Noviello C; D'Adamio L Amyloid-beta protein precursor (A beta PP) intracellular domain-associated protein-1 proteins bind to A beta PP and modulate its processing in an isoform-specific manner | 0 | 0 |
| 117 | 1 | 64 | 75 2004 JOURNAL OF CELL SCIENCE 117 (19): 4435-4448 von Rotz RC; Kohli BM; Bosset J; Meier M; Suzuki T; et al. The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor | 1 | 4 |
| 118 | 1 | 57 | 76 2004 JOURNAL OF NEUROCHEMISTRY 88 (4): 869-877 Smith IF; Boyle JP; Green KN; Pearson HA; Peers C Hypoxic remodelling of Ca2+ mobilization in type I cortical astrocytes: involvement of ROS and pro-amyloidogenic APP processing | 0 | 3 |
| 119 | 1 | 79 | 77 2004 JOURNAL OF NEUROCHEMISTRY 88 (5): 1140-1150 Pierrot N; Ghisdal P; Caumont AS; Octave JN Intraneuronal amyloid-beta 1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death | 0 | 2 |
| 120 | 1 | 59 | 78 2004 JOURNAL OF NEUROCHEMISTRY 89 (1): 44-53 Laudon H; Mathews PM; Karlstrom H; Bergman A; Farmery MR; et al. Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein | 4 | 7 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 121 | 1 | 54 | 80 2004 JOURNAL OF NEUROCHEMISTRY 90 (3): 712-723 van Dijk R; Fischer DF; Sluijs JA; Sonnemans MAF; Hobo B; et al. Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta 40 | 0 | 0 |
| 122 | 1 | 44 | 85 2004 JOURNAL OF VIROLOGY 78 (21): 11766-11777 Ogino T; Fukuda H; Imajoh-Ohmi S; Kohara M; Nomoto A Membrane binding properties and terminal residues of the mature hepatitis C virus capsid protein in insect cells | 0 | 0 |
| 123 | 1 | 77 | 86 2004 MOLECULAR AND CELLULAR BIOLOGY 24 (1): 454-464 Wilhelmsen K; van der Geer P Phorbol 12-myristate 13-acetate-induced release of the colony-stimulating factor 1 receptor cytoplasmic domain into the cytosol involves two separate cleavage events | 1 | 5 |
| 124 | 1 | 46 | 89 2004 MOLECULAR PSYCHIATRY 9 (6): 594-602 Verdile G; Groth D; Mathews PM; St George-Hyslop P; Fraser PE; et al. Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells | 0 | 0 |
| 125 | 1 | 206 | 90 2004 MOLECULAR PSYCHIATRY 9 (7): 664-683 Gotz J; Streffer JR; David D; Schild A; Hoerndli F; et al. Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy | 1 | 7 |
| 126 | 1 | 48 | 91 2004 NATURE BIOTECHNOLOGY 22 (6): 724-731 Schmitt-Ulms G; Hansen K; Liu JL; Cowdrey C; Yang J; et al. Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues | 0 | 2 |
| 127 | 1 | 104 | 92 2004 NATURE CELL BIOLOGY 6 (11): 1054-1061 Selkoe DJ Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases | 0 | 0 |
| 128 | 1 | 107 | 94 2004 NATURE REVIEWS MOLECULAR CELL BIOLOGY 5 (3): 188-197 Freeman M Proteolysis within the membrane: Rhomboids revealed | 1 | 7 |
| 129 | 1 | 57 | 98 2004 NEUROBIOLOGY OF DISEASE 17 (2): 205-218 Hecimovic S; Wang J; Dolios G; Martinez M; Wang R; et al. Mutations in APP have independent effects on A beta and CTF gamma generation | 3 | 3 |
| 130 | 1 | 127 | 102 2004 PHARMACOLOGICAL RESEARCH 50 (4): 397-409 Verdile G; Fuller S; Atwood CS; Laws SM; Gandy SE; et al. The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught? | 0 | 0 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 131 | 1 | 105 | 103 2004 PHARMACOLOGICAL RESEARCH 50 (4): 411-418 Thinakaran G; Parent AT Identification of the role of presenilins beyond Alzheimer's disease | 1 | 4 |
| 132 | 1 | 22 | 104 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (4): 905-906 Kim J; Schekman R The ins and outs of presenilin 1 membrane topology | 2 | 3 |
| 133 | 1 | 110 | 106 2004 SEMINARS IN CANCER BIOLOGY 14 (5): 320-328 Hansson EM; Lendahl U; Chapman G Notch signaling in development and disease | 1 | 5 |
| 134 | 1 | 50 | 107 2005 AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 132B (1): 14-20 Wijsman EM; Daw EW; Yu XS; Steinbart EJ; Nochlin D; et al. APOE and other loci affect age-at-onset in Alzheimer's disease families with PS2 mutation | 0 | 0 |
| 135 | 1 | 70 | 113 2005 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1739 (2-3): 260-267 King ME Can tau filaments be both physiologically beneficial and toxic? | 0 | 0 |
| 136 | 1 | 22 | 114 2005 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 15 (7): 1891-1894 Gundersen E; Fan K; Haas K; Huryn D; Jacobsen JS; et al. Molecular-modeling based design, synthesis, and activity of substituted piperidines as gamma-secretase inhibitors | 0 | 0 |
| 137 | 1 | 68 | 116 2005 FEBS JOURNAL 272 (6): 1386-1400 Zabrocki P; Pellens K; Vanhelmont T; Vandebroek T; Griffioen G; et al. Characterization of alpha-synuclein aggregation and synergistic toxicity with protein tau in yeast | 0 | 0 |
| 138 | 1 | 54 | 121 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (9): 7758-7768 Kim J; Hamamoto S; Ravazzola M; Orci L; Schekman R Uncoupled packaging of amyloid precursor protein and presenilin 1 into coat protein complex II vesicles | 0 | 0 |
| 139 | 1 | 40 | 122 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (10): 9313-9319 Haas IG; Frank M; Veron N; Kemler R Presenilin-dependent processing and nuclear function of gamma-protocadherins | 0 | 0 |
| 140 | 1 | 38 | 131 2005 JOURNAL OF NEUROCHEMISTRY 92 (2): 294-301 Walker ES; Martinez M; Brunkan AL; Goate A Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in A beta 42/40 ratios | 1 | 1 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 141 | 0 | 15 | 20 2003 NATURE CELL BIOLOGY 5 (5): 486-488 Edbauer D; Winkler E; Regula JT; Pesold B; Steiner H; et al. Reconstitution of gamma-secretase activity | 140 | 140 |
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