Missing Links? Citation Matrix | Graphs | Glossary HistCite Guide About |
Nodes: 141,
Authors: 523,
Journals: 55,
Outer References: 4251,
Words: 603
Collection span: 2003 - 2005
View: Overview. Sorted by first author.
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# | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
---|---|---|---|---|---|
101 | 1 | 104 | 92 2004 NATURE CELL BIOLOGY 6 (11): 1054-1061 Selkoe DJ Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases | 0 | 0 |
102 | 6 | 28 | 139 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (5): 1719-1724 Serneels L; Dejaegere T; Craessaerts K; Horre K; Jorissen E; et al. Differential contribution of the three Aph1 genes to gamma-secretase activity in vivoi | 2 | 2 |
103 | 1 | 26 | 64 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (41): 43046-43051 Shen JS; Prywes R Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6 | 0 | 0 |
104 | 10 | 62 | 82 2004 JOURNAL OF NEUROCHEMISTRY 90 (6): 1402-1413 Shiraishi H; Sai X; Wang HQ; Maeda Y; Kurono Y; et al. PEN-2 enhances gamma-cleavage after presenilin heterodimer formation | 0 | 0 |
105 | 10 | 56 | 63 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (40): 41340-41345 Shirotani K; Edbauer D; Prokop S; Haass C; Steiner H Identification of distinct gamma-secretase complexes with different APH-1 variants | 7 | 8 |
106 | 6 | 42 | 79 2004 JOURNAL OF NEUROCHEMISTRY 89 (6): 1520-1527 Shirotani K; Edbauer D; Kostka M; Steiner H; Haass C Immature nicastrin stabilizes APH-1 independent of PEN-2 and presenilin: identification of nicastrin mutants that selectively interact with APH-1 | 8 | 8 |
107 | 5 | 58 | 100 2004 NEUROSCIENCE 129 (3): 615-628 Siman R; Salidas S Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain | 0 | 0 |
108 | 1 | 36 | 47 2004 HUMAN MOLECULAR GENETICS 13: R123-R126 Singleton A; Myers A; Hardy J The law of mass action applied to neurodegenerative disease: a hypothesis concerning the etiology and pathogenesis of complex diseases | 0 | 12 |
109 | 1 | 57 | 76 2004 JOURNAL OF NEUROCHEMISTRY 88 (4): 869-877 Smith IF; Boyle JP; Green KN; Pearson HA; Peers C Hypoxic remodelling of Ca2+ mobilization in type I cortical astrocytes: involvement of ROS and pro-amyloidogenic APP processing | 0 | 3 |
110 | 2 | 204 | 22 2003 REVIEWS IN THE NEUROSCIENCES 14 (4): 317-341 Stein TD; Johnson JA Genetic programming by the proteolytic fragments of the amyloid precursor protein: Somewhere between confusion and clarity | 0 | 4 |
# | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
111 | 2 | 104 | 115 2005 CELL 120 (4): 545-555 Tanzi RE; Bertram L Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective | 0 | 0 |
112 | 6 | 58 | 108 2005 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 328 (1): 1-5 Teng FYH; Tang BL Widespread gamma-secretase activity in the cell, but do we need it at the mitochondria? | 0 | 0 |
113 | 1 | 105 | 103 2004 PHARMACOLOGICAL RESEARCH 50 (4): 411-418 Thinakaran G; Parent AT Identification of the role of presenilins beyond Alzheimer's disease | 1 | 4 |
114 | 1 | 33 | 41 2004 DRUG NEWS & PERSPECTIVES 17 (5): 321-325 Tomita T; Iwatsubo T The inhibition of gamma-secretase as a therapeutic approach to Alzheimer's disease | 1 | 2 |
115 | 1 | 59 | 48 2004 HUMAN MOLECULAR GENETICS 13 (13): 1321-1331 Tournoy J; Bossuyt X; Snellinx A; Regent M; Garmyn M; et al. Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice | 1 | 3 |
116 | 6 | 50 | 129 2005 JOURNAL OF LIPID RESEARCH 46 (5): 904-912 Urano Y; Hayashi I; Isoo N; Reid PC; Shibasaki Y; et al. Association of active gamma-secretase complex with lipid rafts | 0 | 0 |
117 | 3 | 34 | 140 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (6): 1883-1888 Urban S; Wolfe MS Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity | 0 | 1 |
118 | 1 | 54 | 80 2004 JOURNAL OF NEUROCHEMISTRY 90 (3): 712-723 van Dijk R; Fischer DF; Sluijs JA; Sonnemans MAF; Hobo B; et al. Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta 40 | 0 | 0 |
119 | 1 | 46 | 89 2004 MOLECULAR PSYCHIATRY 9 (6): 594-602 Verdile G; Groth D; Mathews PM; St George-Hyslop P; Fraser PE; et al. Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells | 0 | 0 |
120 | 1 | 127 | 102 2004 PHARMACOLOGICAL RESEARCH 50 (4): 397-409 Verdile G; Fuller S; Atwood CS; Laws SM; Gandy SE; et al. The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught? | 0 | 0 |
# | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
121 | 1 | 64 | 75 2004 JOURNAL OF CELL SCIENCE 117 (19): 4435-4448 von Rotz RC; Kohli BM; Bosset J; Meier M; Suzuki T; et al. The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor | 1 | 4 |
122 | 1 | 60 | 2 2003 BIOCHEMISTRY 42 (47): 13977-13986 Wada S; Morishima-Kawashima M; Qi Y; Misono H; Shimada Y; et al. gamma-secretase activity is present in rafts but is not cholesterol-dependent | 2 | 8 |
123 | 1 | 38 | 131 2005 JOURNAL OF NEUROCHEMISTRY 92 (2): 294-301 Walker ES; Martinez M; Brunkan AL; Goate A Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in A beta 42/40 ratios | 1 | 1 |
124 | 8 | 75 | 62 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (39): 40560-40566 Wang H; Luo WJ; Zhang YW; Li YM; Thinakaran G; et al. Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components | 1 | 3 |
125 | 1 | 59 | 8 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (33): 30748-30754 Weggen S; Eriksen JL; Sagi SA; Pietrzik CU; Golde TE; et al. A beta 42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain | 2 | 10 |
126 | 1 | 260 | 35 2004 CLINICAL GENETICS 66 (1): 1-16 Wellington CL Cholesterol at the crossroads: Alzheimer's disease and lipid metabolism | 0 | 0 |
127 | 4 | 103 | 36 2004 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 7 (2): 169-178 Westlund B; Stilwell G; Sluder A Invertebrate disease models in neurotherapeutic discovery | 0 | 0 |
128 | 4 | 67 | 73 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (51): 53205-53212 Westmeyer GG; Willem M; Lichtenthaler SF; Lurman G; Multhaup G; et al. Dimerization of beta-site beta-amyloid precursor protein-cleaving enzyme | 1 | 1 |
129 | 1 | 50 | 107 2005 AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 132B (1): 14-20 Wijsman EM; Daw EW; Yu XS; Steinbart EJ; Nochlin D; et al. APOE and other loci affect age-at-onset in Alzheimer's disease families with PS2 mutation | 0 | 0 |
130 | 1 | 77 | 86 2004 MOLECULAR AND CELLULAR BIOLOGY 24 (1): 454-464 Wilhelmsen K; van der Geer P Phorbol 12-myristate 13-acetate-induced release of the colony-stimulating factor 1 receptor cytoplasmic domain into the cytosol involves two separate cleavage events | 1 | 5 |
# | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
131 | 3 | 58 | 39 2004 CURRENT OPINION IN NEUROBIOLOGY 14 (5): 582-588 Wilquet V; De Strooper B Amyloid-beta precursor protein processing in neurodegeneration | 0 | 1 |
132 | 1 | 112 | 18 2003 JOURNAL OF NEUROSCIENCE RESEARCH 74 (3): 361-369 Wilson CA; Doms RW; Lee VMY Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular A beta production | 3 | 5 |
133 | 9 | 73 | 105 2004 SCIENCE 305 (5687): 1119-1123 Wolfe MS; Kopan R Intramembrane proteotysis: Theme and variations | 4 | 11 |
134 | 2 | 37 | 81 2004 JOURNAL OF NEUROCHEMISTRY 90 (6): 1312-1320 Wrigley JDJ; Nunn EJ; Nyabi O; Clarke EE; Hunt P; et al. Conserved residues within the putative active site of gamma-secretase differentially influence enzyme activity and inhibitor binding | 5 | 5 |
135 | 13 | 77 | 123 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (13): 12523-12535 Wrigley JDJ; Schurov I; Nunn EJ; Martin ACL; Clarke EE; et al. Functional overexpression of gamma-secretase reveals protease-independent trafficking functions and a critical role of lipids for protease activity | 0 | 0 |
136 | 1 | 69 | 15 2003 JOURNAL OF CELL SCIENCE 116 (14): 2839-2844 Xia WM; Wolfe MS Intramembrane proteolysis by presenilin and presenilin-like proteases | 5 | 11 |
137 | 6 | 31 | 130 2005 JOURNAL OF MOLECULAR NEUROSCIENCE 25 (1): 67-77 Xie ZC; Romano DM; Tanzi RE Effects of RNAi-mediated silencing of PEN-2, APH-1a, and nicastrin on wild-type vs FAD mutant forms of presenilin 1 | 0 | 0 |
138 | 2 | 72 | 49 2004 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 36 (12): 2531-2540 Yu WH; Kumar A; Peterhoff C; Kulnane LS; Uchiyama Y; et al. Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease | 1 | 3 |
139 | 1 | 68 | 116 2005 FEBS JOURNAL 272 (6): 1386-1400 Zabrocki P; Pellens K; Vanhelmont T; Vandebroek T; Griffioen G; et al. Characterization of alpha-synuclein aggregation and synergistic toxicity with protein tau in yeast | 0 | 0 |
140 | 2 | 36 | 112 2005 BIOCHEMISTRY 44 (11): 4450-4457 Zhang LL; Lee JL; Song LX; Sun XY; Shen J; et al. Characterization of the reconstituted gamma-secretase complex from Sf9 cells co-expressing presenilin 1, nacastrin, aph-1a, and pen-2 | 0 | 0 |
# | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
141 | 10 | 44 | 125 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (17): 17020-17026 Zhang YW; Luo WJ; Wang H; Lin P; Vetrivel KS; et al. Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components | 0 | 0 |
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