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Wed Jun 1 16:44:10 2005

The role of presenilin cofactors in the gamma-secretase complex
TAKASUGI N, TOMITA T, HAYASHI I, et al.
NATURE 422: 438-441 2003
and the citing papers

Nodes: 130, Authors: 480, Journals: 60, Outer References: 3273, Words: 549
Collection span: 2003 - 2005
View: Overview. Sorted by journal name.
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#LCRNCRNode / Date / Journal / AuthorLCSGCS
101111387 2004 MOLECULAR BRAIN RESEARCH 132 (2): 260-270
Genc S; Koroglu TF; Genc K
RNA interference in neuroscience
00
10235188 2004 MOLECULAR MEMBRANE BIOLOGY 21 (6): 373-383
Harnasch M; Grau S; Behrends C; Dove SL; Hochschild A; et al.
Characterization of presenilin-amyloid precursor interaction using bacterial expression and two-hybrid systems for human membrane proteins
01
10331389 2004 MOLECULAR PSYCHIATRY 9 (1): 8-10
Iwatsubo T
Assembly and activation of the gamma-secretase complex: roles of presenilin cofactors
12
10411126 2003 NATURE 422 (6930): 385-387
Mattson MP
Neurobiology - Ballads of a protein quartet
03
10502827 2003 NATURE 422 (6930): 438-441
Takasugi N; Tomita T; Hayashi I; Tsuruoka M; Niimura M; et al.
The role of presenilin cofactors in the gamma-secretase complex
129130
10619990 2004 NATURE 430 (7000): 631-639
Mattson MP
Pathways towards and away from Alzheimer's disease
033
107110491 2004 NATURE CELL BIOLOGY 6 (11): 1054-1061
Selkoe DJ
Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases
00
10823692 2004 NATURE MEDICINE 10 (9): 959-965
He WX; Lu YF; Qahwash I; Hu XY; Chang AS; et al.
Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation
02
109511193 2004 NATURE REVIEWS NEUROSCIENCE : S26-S33
Koo EH; Kopan R
Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration
00
11015228 2003 NEUROBIOLOGY OF DISEASE 14 (2): 194-204
Baulac S; LaVoie MJ; Kimberly WT; Strahle J; Wolfe MS; et al.
Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates
910
#LCRNCRNode / Date / Journal / AuthorLCSGCS
11114194 2004 NEUROBIOLOGY OF DISEASE 15 (3): 654-666
Wang J; Brunkan AL; Hecimovic S; Walker E; Goate A
Conserved "PAL" sequence in presenilins is essential for gamma-secretase activity, but not required for formation or stabilization of gamma-secretase complexes
37
112146395 2004 NEUROBIOLOGY OF DISEASE 17 (2): 260-272
Hebert SS; Serneels L; Dejaegere T; Horre K; Dabrowski M; et al.
Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity
33
11316296 2004 NEUROCHEMISTRY INTERNATIONAL 44 (5): 313-320
Kametani F; Usami M; Tanaka K; Kume H; Mori H
Mutant presenilin (A260V) affects Rab8 in PC12D cell
00
11411097 2004 NEUROLOGY 63 (9): 1702-1704
Godbolt AK; Beck JA; Collinge J; Garrard P; Warren JD; et al.
A presenilin 1 R278I mutation presenting with language impairment
11
11512229 2003 NEURON 38 (1): 9-12
De Strooper B
Aph-1, Pen-2, and nicastrin with presenilin generate an active gamma-secretase complex
48118
11655898 2004 NEUROSCIENCE 129 (3): 615-628
Siman R; Salidas S
Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain
00
11715499 2004 ONCOGENE 23 (42): 7076-7086
Saleh AZM; Fang AT; Arch AE; Neupane D; El Fiky A; et al.
Regulated proteolysis of the IFNaR2 subunit of the interferon-alpha receptor
01
1181105100 2004 PHARMACOLOGICAL RESEARCH 50 (4): 411-418
Thinakaran G; Parent AT
Identification of the role of presenilins beyond Alzheimer's disease
24
11946730 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (22): 13075-13080
Schroeter EH; Ilagan MXG; Brunkan AL; Hecimovic S; Li YM; et al.
A presenilin dimer at the core of the gamma-secretase enzyme: Insights from parallel analysis of Notch 1 and APP proteolysis
2334
120153101 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (17): 6623-6628
Iijima K; Liu HP; Chiang AS; Hearn SA; Konsolaki M; et al.
Dissecting the pathological effects of human A beta 40 and A beta 42 in Drosophila: A potential model for Alzheimer's disease
010
#LCRNCRNode / Date / Journal / AuthorLCSGCS
121548102 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (49): 17050-17055
Tarassishin L; Yin YI; Bassit L; Li YM
Processing of Notch and amyloid precursor protein by gamma-secretase is spatially distinct
01
122628128 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (5): 1719-1724
Serneels L; Dejaegere T; Craessaerts K; Horre K; Jorissen E; et al.
Differential contribution of the three Aph1 genes to gamma-secretase activity in vivoi
22
123334129 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (6): 1883-1888
Urban S; Wolfe MS
Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity
01
124331130 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (9): 3230-3235
Kornilova AY; Bihel F; Das C; Wolfe MS
The initial substrate-binding site of gamma-secretase is located on presenilin near the active site
00
125125103 2004 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 31 (3): 198-203
Zhou QJ; Hu RZ; Shao JZ; Xiang LX
Notch signal transduction and regulation
00
126320431 2003 REVIEWS IN THE NEUROSCIENCES 14 (4): 317-341
Stein TD; Johnson JA
Genetic programming by the proteolytic fragments of the amyloid precursor protein: Somewhere between confusion and clarity
04
127410432 2003 SCIENCE 302 (5646): 814-818
Aguzzi A; Haass C
Games played by rogue proteins in prion disorders and Alzheimer's disease
223
1281173104 2004 SCIENCE 305 (5687): 1119-1123
Wolfe MS; Kopan R
Intramembrane proteotysis: Theme and variations
311
129314105 2004 SEIKAGAKU 76 (7): 666-670
Tomita T; Iwatsubo T
Recent advances in Alzheimer's disease-related gamma-secretase complex
00
130227106 2004 TETRAHEDRON LETTERS 45 (11): 2323-2326
Fuwa H; Okamura Y; Morohashi Y; Tomita T; Iwatsubo T; et al.
Highly efficient synthesis of medium-sized lactams via intramolecular Staudinger-aza-Wittig reaction of omega-azido pentafluorophenyl ester: synthesis and biological evaluation of LY411575 analogues
03

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