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Nodes: 130,
Authors: 480,
Journals: 60,
Outer References: 3273,
Words: 549
Collection span: 2003 - 2005
View: Overview. Sorted by LCR.
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| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
|---|---|---|---|---|---|
| 101 | 1 | 54 | 21 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (49): 49448-49458 Araki Y; Tomita S; Yamaguchi H; Miyagi N; Sumioka A; et al. Novel cadherin-related membrane proteins, alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism | 1 | 4 |
| 102 | 1 | 24 | 23 2003 JOURNAL OF CELL BIOLOGY 161 (4): 685-690 Hu Y; Fortini ME Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex | 40 | 44 |
| 103 | 1 | 46 | 24 2003 JOURNAL OF CLINICAL INVESTIGATION 112 (3): 440-449 Eriksen JL; Sagi SA; Smith TE; Weggen S; Das P; et al. NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower A beta 42 in vivo | 4 | 34 |
| 104 | 1 | 74 | 25 2003 JOURNAL OF NEUROSCIENCE RESEARCH 74 (3): 353-360 Kimberly WT; Wolfe MS Identity and function of gamma-secretase | 4 | 15 |
| 105 | 1 | 11 | 26 2003 NATURE 422 (6930): 385-387 Mattson MP Neurobiology - Ballads of a protein quartet | 0 | 3 |
| 106 | 1 | 52 | 28 2003 NEUROBIOLOGY OF DISEASE 14 (2): 194-204 Baulac S; LaVoie MJ; Kimberly WT; Strahle J; Wolfe MS; et al. Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates | 9 | 10 |
| 107 | 1 | 22 | 29 2003 NEURON 38 (1): 9-12 De Strooper B Aph-1, Pen-2, and nicastrin with presenilin generate an active gamma-secretase complex | 48 | 118 |
| 108 | 1 | 14 | 33 2004 ACTA PHARMACOLOGICA SINICA 25 (12): 1613-1618 Lu HM; Deng H; Xiao F; Gao Q; Weng W; et al. Down-regulation amyloid beta-protein 42 production by interfering with transcript of presenilin 1 gene with siRNA | 0 | 0 |
| 109 | 1 | 67 | 34 2004 AMERICAN JOURNAL OF PATHOLOGY 165 (5): 1465-1477 Langui D; Girardot N; El Hachimi KH; Allinquant B; Blanchard V; et al. Subcellular topography of neuronal A beta peptide in APPxPS1 transgenic mice | 0 | 0 |
| 110 | 1 | 29 | 40 2004 BIOCHEMISTRY 43 (42): 13532-13540 Funamoto S; Morshima-Kawashima M; Tanimura Y; Hirotani N; Saido TC; et al. Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42 | 0 | 1 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 111 | 1 | 41 | 52 2004 EUROPEAN JOURNAL OF IMMUNOLOGY 34 (4): 1217-1227 Mayne M; Moffatt T; Kong H; McLaren PJ; Fowke KR; et al. CYFIP2 is highly abundant in CD4(+) cells from multiple sclerosis patients and is involved in T cell adhesion | 0 | 0 |
| 112 | 1 | 36 | 55 2004 HUMAN MOLECULAR GENETICS 13: R123-R126 Singleton A; Myers A; Hardy J The law of mass action applied to neurodegenerative disease: a hypothesis concerning the etiology and pathogenesis of complex diseases | 0 | 12 |
| 113 | 1 | 80 | 56 2004 HUMAN MOLECULAR GENETICS 13 (2): 159-170 Jankowsky JL; Fadale DJ; Anderson J; Xu GM; Gonzales V; et al. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase | 0 | 10 |
| 114 | 1 | 24 | 58 2004 INTERNATIONAL JOURNAL OF NEUROSCIENCE 114 (10): 1277-+ Hwang DY; Kim YK; Lim CJ; Cho JS Mutant nicastrin protein can induce the cytochrome c release and the Bax expression | 0 | 0 |
| 115 | 1 | 144 | 59 2004 JOURNAL OF ALZHEIMERS DISEASE 6 (1): 53-65 Pasternak SH; Callahan JW; Mahuran DJ The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: Reexamining the spatial paradox from a lysosomal perspective | 0 | 3 |
| 116 | 1 | 61 | 62 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (6): 4596-4603 Guo Q; Xie J AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with par-4 | 1 | 4 |
| 117 | 1 | 57 | 82 2004 JOURNAL OF NEUROCHEMISTRY 90 (4): 800-806 da Costa CA; Ayral E; Hernandez JF; St George-Hyslop P; Checler F Presenilin-directed inhibitors of gamma-secretase trigger caspase 3 activation in presenilin-expressing and presenilin-deficient cells | 0 | 0 |
| 118 | 1 | 113 | 87 2004 MOLECULAR BRAIN RESEARCH 132 (2): 260-270 Genc S; Koroglu TF; Genc K RNA interference in neuroscience | 0 | 0 |
| 119 | 1 | 99 | 90 2004 NATURE 430 (7000): 631-639 Mattson MP Pathways towards and away from Alzheimer's disease | 0 | 33 |
| 120 | 1 | 104 | 91 2004 NATURE CELL BIOLOGY 6 (11): 1054-1061 Selkoe DJ Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases | 0 | 0 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 121 | 1 | 41 | 94 2004 NEUROBIOLOGY OF DISEASE 15 (3): 654-666 Wang J; Brunkan AL; Hecimovic S; Walker E; Goate A Conserved "PAL" sequence in presenilins is essential for gamma-secretase activity, but not required for formation or stabilization of gamma-secretase complexes | 3 | 7 |
| 122 | 1 | 62 | 96 2004 NEUROCHEMISTRY INTERNATIONAL 44 (5): 313-320 Kametani F; Usami M; Tanaka K; Kume H; Mori H Mutant presenilin (A260V) affects Rab8 in PC12D cell | 0 | 0 |
| 123 | 1 | 10 | 97 2004 NEUROLOGY 63 (9): 1702-1704 Godbolt AK; Beck JA; Collinge J; Garrard P; Warren JD; et al. A presenilin 1 R278I mutation presenting with language impairment | 1 | 1 |
| 124 | 1 | 54 | 99 2004 ONCOGENE 23 (42): 7076-7086 Saleh AZM; Fang AT; Arch AE; Neupane D; El Fiky A; et al. Regulated proteolysis of the IFNaR2 subunit of the interferon-alpha receptor | 0 | 1 |
| 125 | 1 | 105 | 100 2004 PHARMACOLOGICAL RESEARCH 50 (4): 411-418 Thinakaran G; Parent AT Identification of the role of presenilins beyond Alzheimer's disease | 2 | 4 |
| 126 | 1 | 53 | 101 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (17): 6623-6628 Iijima K; Liu HP; Chiang AS; Hearn SA; Konsolaki M; et al. Dissecting the pathological effects of human A beta 40 and A beta 42 in Drosophila: A potential model for Alzheimer's disease | 0 | 10 |
| 127 | 1 | 25 | 103 2004 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 31 (3): 198-203 Zhou QJ; Hu RZ; Shao JZ; Xiang LX Notch signal transduction and regulation | 0 | 0 |
| 128 | 1 | 50 | 107 2005 AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 132B (1): 14-20 Wijsman EM; Daw EW; Yu XS; Steinbart EJ; Nochlin D; et al. APOE and other loci affect age-at-onset in Alzheimer's disease families with PS2 mutation | 0 | 0 |
| 129 | 1 | 70 | 112 2005 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1739 (2-3): 260-267 King ME Can tau filaments be both physiologically beneficial and toxic? | 0 | 0 |
| 130 | 0 | 28 | 27 2003 NATURE 422 (6930): 438-441 Takasugi N; Tomita T; Hayashi I; Tsuruoka M; Niimura M; et al. The role of presenilin cofactors in the gamma-secretase complex | 129 | 130 |
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