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Wed Mar 30 12:22:19 2005
Transcription start regions in the human
genome are favored targets for MLV integration

WU XL, LI Y, CRISE B, et al.
SCIENCE 300: 1749-1751 2003
and the citing papers

Nodes: 99, Authors: 417, Journals: 56, Outer References: 4520, Words: 467
Collection span: 2003 - 2005
View: Overview. Sorted by GCS.
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
113816 2003 SCIENCE 302(5644):415-419
Hacein-Bey-Abina S; Von Kalle C; Schmidt M; McCcormack MP; Wulffraat N; et al.
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
43174
201814 2003 SCIENCE 300(5626):1749-1751
Wu XL; Li Y; Crise B; Burgess SM
Transcription start regions in the human genome are favored targets for MLV integration
9898
328476 2004 SCIENCE 303(5664):1626-1632
Kazazian HH
Mobile elements: Drivers of genome evolution
036
41183 2003 CELL 115(2):135-138
Bushman FD
Targeting survival: Integration site selection by retroviruses and LTR-retrotransposons
1320
529071 2004 NEW ENGLAND JOURNAL OF MEDICINE 350(9):913-922
McCormack MP; Rabbitts TH
Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency
420
62915 2003 SCIENCE 302(5644):400-401
Williams DA; Baum C
Gene therapy - New challenges ahead
316
725461 2004 MOLECULAR THERAPY 9(1):5-13
Baum C; von Kalle C; Staal FJT; Li ZX; Fehse B; et al.
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences
59
823562 2004 MOLECULAR THERAPY 9(3):389-395
Kiem HP; Sellers S; Thomasson B; Morris JC; Tisdale JF; et al.
Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: No progression to clonal hematopoiesis or leukemia
48
91598 2003 DEVELOPMENTAL DYNAMICS 228(3):523-534
Amsterdam A
Insertional mutagenesis in zebrafish
06
1018611 2003 JOURNAL OF VIROLOGY 77(23):12507-12522
Violot S; Hong SS; Rakotobe D; Petit C; Gay B; et al.
The human Polycomb group EED protein interacts with the integrase of human immunodeficiency virus type 1
56
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
1138021 2004 BLOOD 103(11):4062-4069
Hanawa H; Hematti P; Keyvanfar K; Metzger ME; Krouse A; et al.
Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system
46
1213210 2003 GENE THERAPY 10(24):1999-2004
Gaspar HB; Howe S; Thrasher AJ
Gene therapy progress and prospects: gene therapy for severe combined immunodeficiency
15
1313633 2004 DEVELOPMENTAL CELL 7(1):133-144
Kawakami K; Takeda H; Kawakami N; Kobayashi M; Matsuda N; et al.
A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish
05
1438546 2004 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 113(4):595-603
Chinen J; Puck JM
Successes and risks of gene therapy in primary immunodeficiencies
05
1511447 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):529-540
Poeschla EM
Non-primate lentiviral vectors
14
16321637 2004 FRONTIERS IN BIOSCIENCE 9:3187-3208
Turlure F; Devroe E; Silver PA; Engelman A
Human cell proteins and human immunodeficiency virus DNA integration
34
1712840 2004 GENE THERAPY 11(8):711-721
Wang Z; Troilo PJ; Wang X; Griffiths TG; Pacchione SJ; et al.
Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation
04
1817155 2004 JOURNAL OF VIROLOGY 78(12):6122-6133
Han YF; Lassen K; Monie D; Sedaghat AR; Shimoji S; et al.
Resting CD4(+) T cells from human immunodeficiency virus type I (HIV-1)-infected individuals carry integrated HIV-1 Genomes within actively transcribed host genes
24
1917957 2004 JOURNAL OF VIROLOGY 78(17):9524-9537
Llano M; Vanegas M; Fregoso O; Saenz D; Chung S; et al.
LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes
44
2025860 2004 MOLECULAR CELL 13(3):403-414
Hickman AB; Ronning DR; Perez ZN; Kotin RM; Dyda F
The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces
04
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
2114270 2004 NATURE GENETICS 36(3):304-312
Chen WSV; Delrow J; Corrin PD; Frazier JP; Soriano P
Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis
14
221966 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):508-516
Persons DA
Update on gene therapy for hemoglobin disorders
23
2332420 2004 BIOLOGY OF REPRODUCTION 71(2):405-409
Hofmann A; Zakhartchenko V; Weppert M; Sebald H; Wenigerkind H; et al.
Generation of transgenic cattle by lentiviral gene transfer into oocytes
13
2414354 2004 JOURNAL OF VIROLOGY 78(11):5848-5855
Taganov KD; Cuesta I; Daniel R; Cirillo LA; Katz RA; et al.
Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro
13
2544358 2004 JOURNAL OF VIROLOGY 78(21):11656-11663
Narezkina A; Taganov KD; Litwin S; Stoyanova R; Hayashi J; et al.
Genome-wide analyses of avian sarcoma virus integration sites
33
2615175 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(24):9039-9044
Smith S; Hwang JY; Banerjee S; Majeed A; Gupta A; et al.
Mutator genes for suppression of gross chromosomal rearrangements identified by a genome-wide screening in Saccharomyces cerevisiae
03
271375 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):458-462
Baum C; Fehse B
Mutagenesis by retroviral transgene insertion: Risk assessment and potential alternatives
12
2811513 2003 SCIENCE 300(5626):1670-1671
Trono D
Picking the right spot
22
2918332 2004 CURRENT HIV RESEARCH 2(2):185-191
Morris KV; Rossi JJ
Anti-HIV-1 gene expressing lentiviral vectors as an adjunctive therapy for HIV-1 infection
02
30216552 2004 JOURNAL OF GENE MEDICINE 6:S67-S82
Pages JC; Bru T
Toolbox for retrovectorologists
02
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
3114666 2004 MOLECULAR THERAPY 10(2):260-268
Ohlfest JR; Lobitz PD; Perkinson SG; Largaespada DA
Integration and long-term expression in xenografted human glioblastoma cells using a plasmid-based transposon system
22
3229579 2004 SEMINARS IN THROMBOSIS AND HEMOSTASIS 30(2):185-195
Van Damme A; Chuah MKL; Collen D; VandenDriessche T
Onco-Retroviral and lentiviral vector-based gene therapy for hemophilia: Preclinical studies
02
3317480 2004 STEM CELLS 22(3):324-333
Vanderbyl S; MacDonald GN; Sidhu S; Gung L; Telenius A; et al.
Transfer and stable transgene expression of a mammalian artificial chromosome into bone marrow-derived human mesenchymal stem cells
02
3416783 2004 WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE 16(1):23-33
Chandler LA; Sosnowski BA
Gene therapy for cutaneous wound repair
02
351192 2003 BIOTECHNIQUES 35(5):1072-+
Yao AQ; Chiu R; Vora A; Brown DB; Grandgenett D; et al.
Avian retrovirus integrase-enhanced transgene integration into mammalian cell DNA in vivo
01
361524 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(4):376-382
Portlock JL; Calos MP
Site-specific genomic strategies for gene therapy
01
3714626 2004 CANCER RESEARCH 64(13):4419-4427
Shin MS; Fredrickson TN; Hartley JW; Suzuki T; Agaki K; et al.
High-throughput retroviral tagging for identification of genes involved in initiation and progression of mouse splenic marginal zone lymphomas
01
3814434 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(7):1103-1113
Pardridge WM
Intravenous, non-viral RNAi gene therapy of brain cancer
01
3916839 2004 GENE THERAPY 11:S92-S97
Waddington SN; Kennea NL; Buckley SMK; Gregory LG; Themis M; et al.
Fetal and neonatal gene therapy: benefits and pitfalls
01
4015543 2004 HUMAN GENE THERAPY 15(4):361-372
Vargas J; Gusella GL; Najfeld V; Klotman ME; Cara A
Novel integrase-defective lentiviral episomal vectors for gene transfer
01
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
4115044 2004 HUMAN GENE THERAPY 15(5):445-456
Bao LL; Jaligam V; Zhang XY; Kutner RH; Kantrow SP; et al.
Stable transgene expression in tumors and metastases after transduction with lentiviral vectors based on human immunodeficiency virus type 1
01
4227351 2004 JOURNAL OF CLINICAL INVESTIGATION 114(7):953-962
Imren S; Fabry ME; Westerman KA; Pawliuk R; Tang P; et al.
High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells
11
4315356 2004 JOURNAL OF VIROLOGY 78(12):6190-6199
Serhan F; Penaud M; Petit C; Leste-Lasserre T; Trajcevski S; et al.
Early detection of a two-long-terminal-repeat junction molecule in the cytoplasm of recombinant murine leukemia virus-infected cells
01
4421059 2004 M S-MEDECINE SCIENCES 20(1):115-117
Fischer A; Hacein-Bey-Abina S; Cavazzana-Calvo M
Gene therapy of children with X-linked severe combined immune deficiency : efficiency and comlications
01
4518172 2004 ONCOGENE 23(24):4297-4307
Shigesada K; van de Sluis B; Liu PP
Mechanism of leukemogenesis by the inv(16) chimeric gene CBFB/PEBP2B-MHY11
01
4628877 2004 SEMINARS IN HEMATOLOGY 41(4):272-278
Fischer A; Hacein-Bey-Abina S; Cavazzana-Calvo M
Gene therapy for immunodeficiency diseases
01
4727982 2004 TRENDS IN MOLECULAR MEDICINE 10(11):525-531
Lassen K; Han YF; Zhou Y; Siliciano J; Siliciano RF
The multifactorial nature of HIV-1 latency
11
4831999 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(5):1436-1441
Maxfield LF; Fraize CD; Coffin JM
Relationship between retroviral DNA-integration-site selection and host cell transcription
11
491991 2003 ARCHIVES OF MEDICAL RESEARCH 34(6):589-599
Bueren JA; Guenechea G; Casado JA; Lamana ML; Segovia JC
Genetic modification of hematopoietic stem cells: recent advances in the gene therapy of inherited diseases
00
501939 2003 EXPERT OPINION ON BIOLOGICAL THERAPY 3(8):1241-1251
Fruehauf S; Veldwijk MR; Zeller WJ; Laufs S
Prospects and RISC score of viral gene therapy for sarcoma
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511312 2003 QJM-AN INTERNATIONAL JOURNAL OF MEDICINE 96(11):873-874
Berry C
Misplaced
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5236417 2004 AIDS REVIEWS 6(1):13-21
Cereseto A; Giacca M
Integration site selection by retroviruses
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53610818 2004 AIDS REVIEWS 6(4):199-207
Lehmann-Che J; Saib A
Early stages of HIV replication: How to hijack cellular functions for a successful infection
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5464919 2004 BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY 17(3):493-503
Li ZX; Modlich U; Baum C
Safety and efficacy in retrovirally modified haematopoietic cell therapy
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5533822 2004 BLOOD 104(8):2281-2290
Hanawa H; Hargrove PW; Kepes S; Srivastava DK; Nienhuis AW; et al.
Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia
00
5634123 2004 BLOOD 104(12):3445-3453
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Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector
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Tumor cells escape suicide gene therapy by genetic and epigenetic instability
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582425 2004 CANADIAN MEDICAL ASSOCIATION JOURNAL 170(12):1785-1786
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Gene therapy: two steps forward, one step back
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5912227 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(6):721-726
Tsyba L; Rynditch AV; Boeri E; Jabbari K; Bernardi G
Distribution of HIV-1 in the genomes of AIDS patients
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6036628 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(19-20):2588-2596
Wu X; Burgess SM
Integration target site selection for retroviruses and transposable elements
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61133129 2004 CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION 14(1-2):89-136
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Progress toward skeletal gene therapy
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62212830 2004 CURRENT GENE THERAPY 4(3):263-276
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Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors
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Safety considerations associated with development and clinical application of lentiviral vector systems for gene transfer
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The RCAS vector system
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6635438 2004 GENE THERAPY 11:S3-S9
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Retroviral vectors: new applications for an old tool
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67110541 2004 GENETICS 168(3):1159-1176
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Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase
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Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy
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Stem cell gene transfer-efficacy and safety in large animal studies
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Suppression of nonsense-mediated mRNA decay permits unbiased gene trapping in mouse embryonic stem cells
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