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Wed Mar 30 12:22:19 2005
Transcription start regions in the human
genome are favored targets for MLV integration

WU XL, LI Y, CRISE B, et al.
SCIENCE 300: 1749-1751 2003
and the citing papers

Nodes: 99, Authors: 417, Journals: 56, Outer References: 4520, Words: 467
Collection span: 2003 - 2005
View: Overview. Sorted by LCS.
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
101814 2003 SCIENCE 300(5626):1749-1751
Wu XL; Li Y; Crise B; Burgess SM
Transcription start regions in the human genome are favored targets for MLV integration
9898
213816 2003 SCIENCE 302(5644):415-419
Hacein-Bey-Abina S; Von Kalle C; Schmidt M; McCcormack MP; Wulffraat N; et al.
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
43174
31183 2003 CELL 115(2):135-138
Bushman FD
Targeting survival: Integration site selection by retroviruses and LTR-retrotransposons
1320
418611 2003 JOURNAL OF VIROLOGY 77(23):12507-12522
Violot S; Hong SS; Rakotobe D; Petit C; Gay B; et al.
The human Polycomb group EED protein interacts with the integrase of human immunodeficiency virus type 1
56
525461 2004 MOLECULAR THERAPY 9(1):5-13
Baum C; von Kalle C; Staal FJT; Li ZX; Fehse B; et al.
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences
59
638021 2004 BLOOD 103(11):4062-4069
Hanawa H; Hematti P; Keyvanfar K; Metzger ME; Krouse A; et al.
Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system
46
717957 2004 JOURNAL OF VIROLOGY 78(17):9524-9537
Llano M; Vanegas M; Fregoso O; Saenz D; Chung S; et al.
LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes
44
823562 2004 MOLECULAR THERAPY 9(3):389-395
Kiem HP; Sellers S; Thomasson B; Morris JC; Tisdale JF; et al.
Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: No progression to clonal hematopoiesis or leukemia
48
929071 2004 NEW ENGLAND JOURNAL OF MEDICINE 350(9):913-922
McCormack MP; Rabbitts TH
Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency
420
102915 2003 SCIENCE 302(5644):400-401
Williams DA; Baum C
Gene therapy - New challenges ahead
316
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
11321637 2004 FRONTIERS IN BIOSCIENCE 9:3187-3208
Turlure F; Devroe E; Silver PA; Engelman A
Human cell proteins and human immunodeficiency virus DNA integration
34
1244358 2004 JOURNAL OF VIROLOGY 78(21):11656-11663
Narezkina A; Taganov KD; Litwin S; Stoyanova R; Hayashi J; et al.
Genome-wide analyses of avian sarcoma virus integration sites
33
131966 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):508-516
Persons DA
Update on gene therapy for hemoglobin disorders
23
1411513 2003 SCIENCE 300(5626):1670-1671
Trono D
Picking the right spot
22
1517155 2004 JOURNAL OF VIROLOGY 78(12):6122-6133
Han YF; Lassen K; Monie D; Sedaghat AR; Shimoji S; et al.
Resting CD4(+) T cells from human immunodeficiency virus type I (HIV-1)-infected individuals carry integrated HIV-1 Genomes within actively transcribed host genes
24
1614666 2004 MOLECULAR THERAPY 10(2):260-268
Ohlfest JR; Lobitz PD; Perkinson SG; Largaespada DA
Integration and long-term expression in xenografted human glioblastoma cells using a plasmid-based transposon system
22
171375 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):458-462
Baum C; Fehse B
Mutagenesis by retroviral transgene insertion: Risk assessment and potential alternatives
12
1811447 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(5):529-540
Poeschla EM
Non-primate lentiviral vectors
14
1913210 2003 GENE THERAPY 10(24):1999-2004
Gaspar HB; Howe S; Thrasher AJ
Gene therapy progress and prospects: gene therapy for severe combined immunodeficiency
15
2032420 2004 BIOLOGY OF REPRODUCTION 71(2):405-409
Hofmann A; Zakhartchenko V; Weppert M; Sebald H; Wenigerkind H; et al.
Generation of transgenic cattle by lentiviral gene transfer into oocytes
13
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
2127351 2004 JOURNAL OF CLINICAL INVESTIGATION 114(7):953-962
Imren S; Fabry ME; Westerman KA; Pawliuk R; Tang P; et al.
High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells
11
2214354 2004 JOURNAL OF VIROLOGY 78(11):5848-5855
Taganov KD; Cuesta I; Daniel R; Cirillo LA; Katz RA; et al.
Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro
13
2314270 2004 NATURE GENETICS 36(3):304-312
Chen WSV; Delrow J; Corrin PD; Frazier JP; Soriano P
Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis
14
2427982 2004 TRENDS IN MOLECULAR MEDICINE 10(11):525-531
Lassen K; Han YF; Zhou Y; Siliciano J; Siliciano RF
The multifactorial nature of HIV-1 latency
11
2531999 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(5):1436-1441
Maxfield LF; Fraize CD; Coffin JM
Relationship between retroviral DNA-integration-site selection and host cell transcription
11
261991 2003 ARCHIVES OF MEDICAL RESEARCH 34(6):589-599
Bueren JA; Guenechea G; Casado JA; Lamana ML; Segovia JC
Genetic modification of hematopoietic stem cells: recent advances in the gene therapy of inherited diseases
00
271192 2003 BIOTECHNIQUES 35(5):1072-+
Yao AQ; Chiu R; Vora A; Brown DB; Grandgenett D; et al.
Avian retrovirus integrase-enhanced transgene integration into mammalian cell DNA in vivo
01
281524 2003 CURRENT OPINION IN MOLECULAR THERAPEUTICS 5(4):376-382
Portlock JL; Calos MP
Site-specific genomic strategies for gene therapy
01
291598 2003 DEVELOPMENTAL DYNAMICS 228(3):523-534
Amsterdam A
Insertional mutagenesis in zebrafish
06
301939 2003 EXPERT OPINION ON BIOLOGICAL THERAPY 3(8):1241-1251
Fruehauf S; Veldwijk MR; Zeller WJ; Laufs S
Prospects and RISC score of viral gene therapy for sarcoma
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
311312 2003 QJM-AN INTERNATIONAL JOURNAL OF MEDICINE 96(11):873-874
Berry C
Misplaced
00
3236417 2004 AIDS REVIEWS 6(1):13-21
Cereseto A; Giacca M
Integration site selection by retroviruses
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33610818 2004 AIDS REVIEWS 6(4):199-207
Lehmann-Che J; Saib A
Early stages of HIV replication: How to hijack cellular functions for a successful infection
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3464919 2004 BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY 17(3):493-503
Li ZX; Modlich U; Baum C
Safety and efficacy in retrovirally modified haematopoietic cell therapy
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3533822 2004 BLOOD 104(8):2281-2290
Hanawa H; Hargrove PW; Kepes S; Srivastava DK; Nienhuis AW; et al.
Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia
00
3634123 2004 BLOOD 104(12):3445-3453
Puthenveetil G; Scholes J; Carbonell D; Oureshi N; Xia P; et al.
Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector
00
3723324 2004 BLOOD 104(12):3543-3549
Frank O; Rudolph C; Heberlein C; von Neuhoff N; Schrock E; et al.
Tumor cells escape suicide gene therapy by genetic and epigenetic instability
00
382425 2004 CANADIAN MEDICAL ASSOCIATION JOURNAL 170(12):1785-1786
Johnston J; Baylis F
Gene therapy: two steps forward, one step back
00
3914626 2004 CANCER RESEARCH 64(13):4419-4427
Shin MS; Fredrickson TN; Hartley JW; Suzuki T; Agaki K; et al.
High-throughput retroviral tagging for identification of genes involved in initiation and progression of mouse splenic marginal zone lymphomas
01
4012227 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(6):721-726
Tsyba L; Rynditch AV; Boeri E; Jabbari K; Bernardi G
Distribution of HIV-1 in the genomes of AIDS patients
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
4136628 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(19-20):2588-2596
Wu X; Burgess SM
Integration target site selection for retroviruses and transposable elements
00
42133129 2004 CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION 14(1-2):89-136
Klamut HJ; Chen ST; Lau KHW; Baylink DJ
Progress toward skeletal gene therapy
00
43212830 2004 CURRENT GENE THERAPY 4(3):263-276
Haviernik P; Bunting KD
Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors
00
4419731 2004 CURRENT GENOMICS 5(1):19-35
Buchschacher GL
Safety considerations associated with development and clinical application of lentiviral vector systems for gene transfer
00
4518332 2004 CURRENT HIV RESEARCH 2(2):185-191
Morris KV; Rossi JJ
Anti-HIV-1 gene expressing lentiviral vectors as an adjunctive therapy for HIV-1 infection
02
4613633 2004 DEVELOPMENTAL CELL 7(1):133-144
Kawakami K; Takeda H; Kawakami N; Kobayashi M; Matsuda N; et al.
A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish
05
4714434 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(7):1103-1113
Pardridge WM
Intravenous, non-viral RNAi gene therapy of brain cancer
01
48312635 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(9):1423-1434
Barese CN; Goebel WS; Dinauer MC
Gene therapy for chronic granulomatous disease
00
4924536 2004 FOLIA BIOLOGICA 50(3-4):107-119
Hughes SH
The RCAS vector system
00
5035438 2004 GENE THERAPY 11:S3-S9
Barquinero J; Eixarch H; Perez-Melgosa M
Retroviral vectors: new applications for an old tool
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5116839 2004 GENE THERAPY 11:S92-S97
Waddington SN; Kennea NL; Buckley SMK; Gregory LG; Themis M; et al.
Fetal and neonatal gene therapy: benefits and pitfalls
01
5212840 2004 GENE THERAPY 11(8):711-721
Wang Z; Troilo PJ; Wang X; Griffiths TG; Pacchione SJ; et al.
Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation
04
53110541 2004 GENETICS 168(3):1159-1176
Aye M; Irwin B; Beliakova-Bethell N; Chen E; Garrus J; et al.
Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae
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5425642 2004 GENOME BIOLOGY 5(10)
Peterson-Burch BD; Nettleton D; Voytas DF
Genomic neighborhoods for Arabidopsis retrotransposons: a role for targeted integration in the distribution of the Metaviridae
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5515543 2004 HUMAN GENE THERAPY 15(4):361-372
Vargas J; Gusella GL; Najfeld V; Klotman ME; Cara A
Novel integrase-defective lentiviral episomal vectors for gene transfer
01
5615044 2004 HUMAN GENE THERAPY 15(5):445-456
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5725045 2004 HUMAN GENE THERAPY 15(8):758-769
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Successes and risks of gene therapy in primary immunodeficiencies
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Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase
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6034848 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(53):55570-55577
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Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase
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61214549 2004 JOURNAL OF BIOMEDICAL SCIENCE 11(4):439-449
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Lentiviral vectors
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Lenti in red: progress in gene therapy for human hemoglobinopathies
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Early detection of a two-long-terminal-repeat junction molecule in the cytoplasm of recombinant murine leukemia virus-infected cells
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