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Nodes: 175,
Authors: 686,
Journals: 90,
Outer References: 7930,
Words: 670
Collection span: 2003 - 2005
View: Overview. Sorted by GCS.
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 0 | 38 | 5 2003 SCIENCE 302(5644):415-419 Hacein-Bey-Abina S; Von Kalle C; Schmidt M; McCcormack MP; Wulffraat N; et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 | 174 | 174 |
| 2 | 1 | 84 | 121 2004 SCIENCE 303(5664):1626-1632 Kazazian HH Mobile elements: Drivers of genome evolution | 0 | 36 |
| 3 | 1 | 7 | 119 2004 SCIENCE 303(5656):333-333 Dave UP; Jenkins NA; Copeland NG Gene therapy insertional mutagenesis insights | 21 | 28 |
| 4 | 3 | 9 | 104 2004 NATURE 427(6977):779-781 Cavazzana-Calvo M; Thrasher A; Mavilio F The future of gene therapy | 13 | 23 |
| 5 | 1 | 90 | 112 2004 NEW ENGLAND JOURNAL OF MEDICINE 350(9):913-922 McCormack MP; Rabbitts TH Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency | 14 | 20 |
| 6 | 1 | 9 | 4 2003 SCIENCE 302(5644):400-401 Williams DA; Baum C Gene therapy - New challenges ahead | 9 | 16 |
| 7 | 1 | 81 | 93 2004 MOLECULAR THERAPY 9(2):147-156 Izsvak Z; Ivics Z Sleeping Beauty transposition: Biology and applications for molecular therapy | 2 | 12 |
| 8 | 1 | 21 | 120 2004 SCIENCE 303(5661):1198-1201 Chamberlain JR; Schwarze U; Wang PR; Hirata RK; Hankenson KD; et al. Gene targeting in stem cells from individuals with osteogenesis imperfecta | 1 | 12 |
| 9 | 2 | 127 | 109 2004 NATURE REVIEWS GENETICS 5(5):355-365 Mittal V Improving the efficiency of RNA interference in mammals | 0 | 11 |
| 10 | 1 | 54 | 92 2004 MOLECULAR THERAPY 9(1):5-13 Baum C; von Kalle C; Staal FJT; Li ZX; Fehse B; et al. Chance or necessity? Insertional mutagenesis in gene therapy and its consequences | 5 | 9 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 1 | 35 | 94 2004 MOLECULAR THERAPY 9(3):389-395 Kiem HP; Sellers S; Thomasson B; Morris JC; Tisdale JF; et al. Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: No progression to clonal hematopoiesis or leukemia | 5 | 8 |
| 12 | 1 | 97 | 10 2004 ANNUAL REVIEW OF IMMUNOLOGY 22:625-655 Buckley RH Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution | 1 | 7 |
| 13 | 1 | 16 | 76 2004 JOURNAL OF GENE MEDICINE 6(6):597-602 Edelstein ML; Abedi MR; Wixon J; Edelstein RM Gene therapy clinical trials worldwide 1989-2004 - an overview | 3 | 7 |
| 14 | 2 | 80 | 19 2004 BLOOD 103(11):4062-4069 Hanawa H; Hematti P; Keyvanfar K; Metzger ME; Krouse A; et al. Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system | 3 | 6 |
| 15 | 3 | 6 | 113 2004 NEW ENGLAND JOURNAL OF MEDICINE 350(16):1679-1680 Berns A Good news for gene therapy | 3 | 6 |
| 16 | 1 | 85 | 66 2004 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 113(4):595-603 Chinen J; Puck JM Successes and risks of gene therapy in primary immunodeficiencies | 4 | 5 |
| 17 | 1 | 58 | 90 2004 MOLECULAR CELL 13(3):403-414 Hickman AB; Ronning DR; Perez ZN; Kotin RM; Dyda F The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces | 0 | 4 |
| 18 | 2 | 24 | 16 2004 BIOLOGY OF REPRODUCTION 71(2):405-409 Hofmann A; Zakhartchenko V; Weppert M; Sebald H; Wenigerkind H; et al. Generation of transgenic cattle by lentiviral gene transfer into oocytes | 1 | 3 |
| 19 | 2 | 45 | 20 2004 BLOOD 103(11):4070-4077 Kuramoto K; Follmann DA; Hematti P; Sellers S; Agricola BA; et al. Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates | 2 | 3 |
| 20 | 1 | 50 | 84 2004 JOURNAL OF VIROLOGY 78(13):7079-7088 Lu XB; Yu Q; Binder GK; Chen ZP; Slepushkina T; et al. Antisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistance | 2 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 1 | 43 | 85 2004 JOURNAL OF VIROLOGY 78(21):11656-11663 Narezkina A; Taganov KD; Litwin S; Stoyanova R; Hayashi J; et al. Genome-wide analyses of avian sarcoma virus integration sites | 3 | 3 |
| 22 | 1 | 69 | 107 2004 NATURE MEDICINE 10(2):135-141 Nabel GJ Genetic, cellular and immune approaches to disease therapy: past and future | 1 | 3 |
| 23 | 1 | 134 | 8 2004 ANNALS OF MEDICINE 36(7):504-517 Boneva RS; Folks TM Xenotransplantation and risks of zoonotic infections | 0 | 2 |
| 24 | 1 | 85 | 26 2004 BRITISH JOURNAL OF HAEMATOLOGY 126(1):3-10 Izraeli S Leukaemia - a developmental perspective | 0 | 2 |
| 25 | 1 | 51 | 35 2004 CLINICAL IMMUNOLOGY 111(3):262-274 Bernstein WB; Cox JH; Aronson NE; Tracy LR; Schlienger K; et al. Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons | 0 | 2 |
| 26 | 2 | 81 | 40 2004 CURRENT OPINION IN INFECTIOUS DISEASES 17(1):17-26 Whitney JB; Ruprecht RM Live attenuated HIV vaccines: pitfalls and prospects | 0 | 2 |
| 27 | 1 | 173 | 45 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(5):631-644 Audet J Stem cell bioengineering for regenerative medicine | 0 | 2 |
| 28 | 2 | 26 | 54 2004 GENE THERAPY 11(7):569-573 Sadelain M Insertional oncogenesis in gene therapy: how much of a risk? | 1 | 2 |
| 29 | 1 | 165 | 75 2004 JOURNAL OF GENE MEDICINE 6:S67-S82 Pages JC; Bru T Toolbox for retrovectorologists | 0 | 2 |
| 30 | 1 | 38 | 82 2004 JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS 199(1):78-86 Streck CJ; Zhou JF; Ng CY; Zhang YB; Nathwani AC; et al. Longterm recombinant adeno-associated, virus-mediated, liver-generated expression of an angiogenesis inhibitor improves survival in mice with disseminated neuroblastoma | 1 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 1 | 32 | 91 2004 MOLECULAR GENETICS AND METABOLISM 82(1):4-19 Mango RL; Xu LF; Sands MS; Vogler C; Seiler G; et al. Neonatal retroviral vector-mediated hepatic gene therapy reduces bone, joint, and cartilage disease in mucopolysaccharidosis VII mice and dogs | 2 | 2 |
| 32 | 2 | 5 | 114 2004 NEW ENGLAND JOURNAL OF MEDICINE 350(24):2526-2526 Fischer A; Abina SHB; Thrasher A; von Kalle C; Cavazzana-Calvo M LMO2 and gene therapy for severe combined immunodeficiency | 2 | 2 |
| 33 | 1 | 87 | 129 2004 TRENDS IN BIOTECHNOLOGY 22(6):304-310 Tarner IH; Muller-Ladner U; Fathman CG Targeted gene therapy: frontiers in the development of 'smart drugs' | 0 | 2 |
| 34 | 1 | 83 | 130 2004 TRENDS IN BIOTECHNOLOGY 22(7):371-377 Aris A; Villaverde A Modular protein engineering for non-viral gene therapy | 0 | 2 |
| 35 | 1 | 110 | 9 2004 ANNUAL REVIEW OF GENETICS 38:819-845 McCarty DM; Young SM; Samulski RJ Integration of adeno-associated virus (AAV) and recombinant AAV vectors | 0 | 1 |
| 36 | 1 | 213 | 15 2004 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1704(1):11-35 Dermine S; Gilham DE; Shaw DM; Davidson EJ; Meziane EK; et al. Vaccine and antibody-directed T cell tumour immunotherapy | 0 | 1 |
| 37 | 1 | 116 | 17 2004 BIOLOGY OF THE CELL 96(4):261-269 Delyfer MN; Leveillard T; Mohand-Said S; Hicks D; Picaud S; et al. Inherited retinal degenerations: therapeutic prospects | 0 | 1 |
| 38 | 1 | 37 | 21 2004 BLOOD 104(2):356-363 Soda Y; Tani K; Bal Y; Saiki M; Chen M; et al. A novel maxizyme vector targeting a bcr-abl fusion gene induced specific cell death in Philadelphia chromosome-positive acute lymphoblastic leukemia | 0 | 1 |
| 39 | 2 | 58 | 38 2004 CURRENT OPINION IN BIOTECHNOLOGY 15(5):383-391 Weber W; Fussenegger M Approaches for trigger-inducible viral transgene regulation in geno-based tissue engineering | 0 | 1 |
| 40 | 2 | 51 | 42 2004 CYTOGENETIC AND GENOME RESEARCH 105(2-4):435-441 Sangiuolo F; Novelli G Sequence-specific modification of mouse genomic DNA mediated by gene targeting techniques | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 1 | 58 | 43 2004 EMBO JOURNAL 23(18):3589-3598 Deane JE; Ryan DP; Sunde M; Maher MJ; Guss JM; et al. Tandem LIM domains provide synergistic binding in the LMO4 : Ldb1 complex | 0 | 1 |
| 42 | 2 | 14 | 55 2004 GENE THERAPY 11(11):879-881 Fehse B; Kustikova OS; Bubenheim M; Baum C Pois(s)on - It's a question of dose ... | 1 | 1 |
| 43 | 1 | 15 | 58 2004 HAEMATOLOGICA 89(7):774-776 Mannucci PM; Bonomi AB The future of hemophilia treatment | 0 | 1 |
| 44 | 1 | 54 | 68 2004 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 114(2):398-405 Chinen J; Shearer WT Advances in asthma, allergy and immunology series 2004: Basic and clinical immunology | 1 | 1 |
| 45 | 1 | 109 | 71 2004 JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS 18(1):62-71 Imai C; Campana D Genetic modification of T cells for cancer therapy | 1 | 1 |
| 46 | 1 | 73 | 74 2004 JOURNAL OF CLINICAL INVESTIGATION 114(7):953-962 Imren S; Fabry ME; Westerman KA; Pawliuk R; Tang P; et al. High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells | 1 | 1 |
| 47 | 1 | 42 | 77 2004 JOURNAL OF GENE MEDICINE 6(6):603-615 Schwickerath O; Brouns G; Thrasher A; Kinnon C; Roes J; et al. Enhancer-deleted retroviral vectors restore high levels of superoxide generation in a mouse model of CGD | 0 | 1 |
| 48 | 1 | 37 | 78 2004 JOURNAL OF GENE MEDICINE 6(9):963-973 Lu XB; Humeau L; Slepushkin V; Binder G; Yu Q; et al. Safe two-plasmid production for the first clinical lentivirus vector that achieves > 99% transduction in primary cells using a one-step protocol | 0 | 1 |
| 49 | 1 | 47 | 81 2004 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 36(3):333-341 Kankkonen HM; Turunen MP; Hiltunen MO; Lehtolainen P; Koponen J; et al. Feline immunodeficiency virus and retrovirus-mediated adventitial ex vivo gene transfer to rabbit carotid artery using autologous vascular smooth muscle cells | 0 | 1 |
| 50 | 1 | 8 | 86 2004 LANCET 364(9452):2155-2156 Cavazzana-Calvo M; Fischer A Efficacy of gene therapy for SCID is being confirmed | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 1 | 10 | 89 2004 M S-MEDECINE SCIENCES 20(1):115-117 Fischer A; Hacein-Bey-Abina S; Cavazzana-Calvo M Gene therapy of children with X-linked severe combined immune deficiency : efficiency and comlications | 0 | 1 |
| 52 | 1 | 35 | 97 2004 MOLECULAR THERAPY 10(1):37-44 Xu LF; O'Malley T; Sands MS; Wang B; Meyerrose T; et al. In vivo transduction of hematopoietic stem cells after. neonatal intravenous injection of an amphotropic retroviral vector in mice | 1 | 1 |
| 53 | 2 | 45 | 117 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(46):16298-16303 Takacs K; Du Roure C; Nabarro S; Dillon N; McVey JH; et al. The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes | 0 | 1 |
| 54 | 2 | 88 | 123 2004 SEMINARS IN HEMATOLOGY 41(4):272-278 Fischer A; Hacein-Bey-Abina S; Cavazzana-Calvo M Gene therapy for immunodeficiency diseases | 1 | 1 |
| 55 | 1 | 73 | 124 2004 SEMINARS IN HEMATOLOGY 41(4):287-296 Lozier J Gene therapy of the hemophilias | 0 | 1 |
| 56 | 4 | 87 | 127 2004 TECHNOLOGY IN CANCER RESEARCH & TREATMENT 3(5):467-477 Lundstrom K Gene therapy applications of viral vectors | 0 | 1 |
| 57 | 3 | 90 | 132 2004 VOX SANGUINIS 87:235-242 Sadelain M Globin gene transfer as a potential treatment for the beta-thalassaemias and sickle cell disease | 1 | 1 |
| 58 | 3 | 43 | 133 2004 VOX SANGUINIS 87(2):73-81 Nathwani AC; Benjamin R; Nienhuis AW; Davidoff AM Current status and prospects for gene therapy | 0 | 1 |
| 59 | 1 | 20 | 142 2005 BRITISH MEDICAL JOURNAL 330(7482):79-82 Kimmelman J Recent developments in gene transfer: risk and ethics | 0 | 1 |
| 60 | 1 | 56 | 169 2005 NUCLEIC ACIDS RESEARCH 33(2):587-596 Basu J; Stromberg G; Compitello G; Willard HF; van Bokkelen G Rapid creation of BAC-based human artificial chromosome vectors by transposition with synthetic alpha-satellite arrays | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 2 | 19 | 174 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(5):1436-1441 Maxfield LF; Fraize CD; Coffin JM Relationship between retroviral DNA-integration-site selection and host cell transcription | 1 | 1 |
| 62 | 1 | 61 | 1 2003 BIOTECHNIQUES 35(6):1273-+ Spangrude GJ Future challenges for hematopoietic stem cell research | 0 | 0 |
| 63 | 1 | 12 | 2 2003 ISRAEL MEDICAL ASSOCIATION JOURNAL 5(12):883-884 Etzioni A Gene therapy - Where do we go? | 0 | 0 |
| 64 | 1 | 1 | 3 2003 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 290(19):2535-2535 [Anon] Gene therapy-leukemia link | 0 | 0 |
| 65 | 1 | 64 | 6 2004 AIDS REVIEWS 6(1):13-21 Cereseto A; Giacca M Integration site selection by retroviruses | 0 | 0 |
| 66 | 1 | 108 | 7 2004 AIDS REVIEWS 6(4):199-207 Lehmann-Che J; Saib A Early stages of HIV replication: How to hijack cellular functions for a successful infection | 0 | 0 |
| 67 | 7 | 49 | 11 2004 BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY 17(3):493-503 Li ZX; Modlich U; Baum C Safety and efficacy in retrovirally modified haematopoietic cell therapy | 0 | 0 |
| 68 | 4 | 57 | 12 2004 BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY 17(3):505-516 Aiuti A Gene therapy for adenosine-deaminase-deficient severe combined immunodeficiency | 0 | 0 |
| 69 | 1 | 100 | 13 2004 BEST PRACTICE & RESEARCH IN CLINICAL OBSTETRICS & GYNAECOLOGY 18(6):853-875 O'Donoghue K; Fisk NM Fetal stem cells | 0 | 0 |
| 70 | 1 | 33 | 14 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 320(3):998-1006 Condiotti R; Curran MA; Nolan GP; Giladi H; Ketzinel-Gilad M; et al. Prolonged liver-specific transgene expression by a non-primate lentiviral vector | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 1 | 3 | 18 2004 BLOOD 103(2):373-374 Rosenzweig M Added challenges to gene therapy - immune responses in the setting of myeloablation | 0 | 0 |
| 72 | 1 | 2 | 22 2004 BLOOD 104(11):86A-86A Schwarzwaelder K; Schmidt M; Howe S; Prinz C; Wissler M; et al. Sustained polyclonal hematopoietic repopulation after successful SCID-X1 gene therapy by means of a non random integrating pseudotyped gammaretrovector | 0 | 0 |
| 73 | 1 | 5 | 23 2004 BLOOD 104(12):3419-3419 Sorrentino BP One step closer to gene therapy for hemoglobinopathies | 0 | 0 |
| 74 | 2 | 41 | 24 2004 BLOOD 104(12):3445-3453 Puthenveetil G; Scholes J; Carbonell D; Oureshi N; Xia P; et al. Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector | 0 | 0 |
| 75 | 1 | 33 | 25 2004 BLOOD 104(12):3543-3549 Frank O; Rudolph C; Heberlein C; von Neuhoff N; Schrock E; et al. Tumor cells escape suicide gene therapy by genetic and epigenetic instability | 0 | 0 |
| 76 | 2 | 11 | 27 2004 BRITISH MEDICAL JOURNAL 329(7470):839-842 Relph K; Harrington K; Pandha H Recent developments and current status of gene therapy using viral vectors in the United Kingdom | 0 | 0 |
| 77 | 1 | 4 | 28 2004 CANADIAN MEDICAL ASSOCIATION JOURNAL 170(12):1785-1786 Johnston J; Baylis F Gene therapy: two steps forward, one step back | 0 | 0 |
| 78 | 1 | 109 | 29 2004 CANCER BIOLOGY & THERAPY 3(1):13-20 Lin YW; Aplan PD Leukemic transformation | 0 | 0 |
| 79 | 2 | 13 | 30 2004 CANCER CELL 5(3):203-204 Braun BS; Shannon K The sum is greater than the FGFR1 partner | 0 | 0 |
| 80 | 1 | 74 | 31 2004 CARDIOVASCULAR RESEARCH 64(2):208-216 Sharif F; Daly K; Crowley J; O'Brien T Current status of catheter-and stent-based gene therapy | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 1 | 224 | 32 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(18):2361-2385 Orange JS; Stone KD; Turvey SE; Krzewski K The Wiskott-Aldrich syndrome | 0 | 0 |
| 82 | 1 | 66 | 33 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(19-20):2588-2596 Wu X; Burgess SM Integration target site selection for retroviruses and transposable elements | 0 | 0 |
| 83 | 1 | 47 | 34 2004 CIRCULATION 110(21):3378-3383 Frangioni JV; Hajjar RJ In vivo tracking of stem cells for clinical trials in cardiovascular disease | 0 | 0 |
| 84 | 1 | 230 | 36 2004 CRITICAL REVIEWS IN IMMUNOLOGY 24(2):87-110 Nagy ZS; Ross J; Cheng HY; Stepkowski SM; Kirken RA Regulation of lymphoid cell apoptosis by Jaks and Stats | 0 | 0 |
| 85 | 1 | 128 | 37 2004 CURRENT GENE THERAPY 4(3):263-276 Haviernik P; Bunting KD Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors | 0 | 0 |
| 86 | 3 | 60 | 39 2004 CURRENT OPINION IN CELL BIOLOGY 16(6):713-720 Mayhall EA; Paffett-Lugassy N; Zon LI The clinical potential of stem cells | 0 | 0 |
| 87 | 6 | 11 | 41 2004 CURRENT OPINION IN MOLECULAR THERAPEUTICS 6(4):358-359 Gunzburg WH Editorial overview - A milestone year for gene therapy goes unnoticed | 0 | 0 |
| 88 | 1 | 45 | 44 2004 EXPERIMENTAL CELL RESEARCH 298(2):611-623 Jakobsson J; Rosenqvist N; Thompson L; Barraud P; Lundberg C Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator | 0 | 0 |
| 89 | 1 | 243 | 46 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(7):1073-1091 Prieto J; Qian C; Hernandez-Alcoceba R; Gonzalez-Aseguinolaza G; Mazzolini G; et al. Gene therapy of liver diseases | 0 | 0 |
| 90 | 2 | 64 | 47 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(9):1403-1412 Prasmickaite L; Hogset A; Engesaeter BO; Bonsted A; Berg K Light-directed gene delivery by photochemical internalisation | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 2 | 126 | 48 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(9):1423-1434 Barese CN; Goebel WS; Dinauer MC Gene therapy for chronic granulomatous disease | 0 | 0 |
| 92 | 2 | 64 | 49 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(9):1435-1443 Bauer JW; Laimer M Gene therapy of epidermolysis bullosa | 0 | 0 |
| 93 | 1 | 71 | 50 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(12):1921-1929 Borkhardt A; Heidenreich O RNA interference as a potential tool in the treatment of leukaemia | 0 | 0 |
| 94 | 4 | 54 | 51 2004 GENE THERAPY 11:S3-S9 Barquinero J; Eixarch H; Perez-Melgosa M Retroviral vectors: new applications for an old tool | 0 | 0 |
| 95 | 1 | 49 | 52 2004 GENE THERAPY 11:S57-S63 Del Rio M; Gache Y; Jorcano JL; Meneguzzi G; Larcher F Current approaches and perspectives in human keratinocyte-based gene therapies | 0 | 0 |
| 96 | 1 | 105 | 53 2004 GENE THERAPY 11:S76-S84 Nguyen TH; Ferry N Liver gene therapy: advances and hurdles | 0 | 0 |
| 97 | 1 | 49 | 56 2004 GENE THERAPY 11(21):1568-1578 Kraunus J; Schaumann DHS; Meyer J; Modlich U; Fehse B; et al. Self-inactivating retroviral vectors with improved RNA processing | 0 | 0 |
| 98 | 2 | 12 | 57 2004 GENOME BIOLOGY 5(8) Qiao J; Diaz RM; Vile RG Success for gene therapy: render unto Caesar that which is Caesar's | 0 | 0 |
| 99 | 1 | 27 | 59 2004 HAEMOPHILIA 10:47-54 Farrugia A; Manno CS; Evatt BL Emerging and receding risks of therapeutic regimens for haemophilia | 0 | 0 |
| 100 | 2 | 50 | 60 2004 HAEMOPHILIA 10(4):309-318 Nathwani AC; Davidoff AM; Tuddenham EGD Prospects for gene therapy of haemophilia | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 101 | 1 | 86 | 61 2004 HEMATOLOGY JOURNAL 5(2):103-111 Klein C; Baum C Gene therapy for inherited disorders of haematopoietic cells | 0 | 0 |
| 102 | 1 | 30 | 62 2004 HUMAN GENE THERAPY 15(5):457-468 Qiao RL; Zhou BY; Harboe-Schmidt E; Kasahara N; Kim KJ; et al. Subunit-specific coordinate upregulation of sodium pump activity in alveolar epithelial cells by lentivirus-mediated gene transfer | 0 | 0 |
| 103 | 1 | 50 | 63 2004 HUMAN GENE THERAPY 15(8):758-769 Chinnasamy D; Fairbairn LJ; Neuenfeldt J; Treisman JS; Hanson JP; et al. Lentivirus-mediated expression of mutant MGMT(P140K) protects human CD34(+) cells against the combined toxicity of O-6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide | 0 | 0 |
| 104 | 2 | 55 | 64 2004 HUMAN GENE THERAPY 15(11):1131-1154 Crystal RG; Sondhi D; Hackett NR; Kaminsky SM; Worgall S; et al. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis | 0 | 0 |
| 105 | 1 | 13 | 65 2004 INTERNAL MEDICINE JOURNAL 34(11):621-625 Trent RJA; Alexander IE Gene therapy: applications and progress towards the clinic | 0 | 0 |
| 106 | 2 | 24 | 67 2004 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 113(4):607-609 Shearer WT; Cunningham-Rundles C; Ochs HD Primary immunodeficiency: Looking backwards, looking forwards | 0 | 0 |
| 107 | 3 | 24 | 69 2004 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 114(2):406-408 Shearer WT Importance of technology for the future of allergy and immunology | 0 | 0 |
| 108 | 1 | 59 | 70 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(47):48883-48892 Cherepanov P; Devroe E; Silver PA; Engelman A Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase | 0 | 0 |
| 109 | 1 | 145 | 72 2004 JOURNAL OF BIOMEDICAL SCIENCE 11(4):439-449 Lever AML; Strappe PM; Zhao J Lentiviral vectors | 0 | 0 |
| 110 | 3 | 22 | 73 2004 JOURNAL OF CLINICAL INVESTIGATION 114(7):889-891 von Kalle C; Baum C; Williams DA Lenti in red: progress in gene therapy for human hemoglobinopathies | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 111 | 1 | 50 | 79 2004 JOURNAL OF GENE MEDICINE 6(11):1257-1271 Radecke F; Radecke S; Schwarz K Unmodified oligodeoxynucleotides require single-strandedness to induce targeted repair of a chromosomal EGFP gene | 0 | 0 |
| 112 | 1 | 34 | 80 2004 JOURNAL OF HEPATOLOGY 40(2):337-340 Follenzi A; Gupta S The promise of lentiviral gene therapy for liver cancer | 0 | 0 |
| 113 | 1 | 15 | 83 2004 JOURNAL OF THROMBOSIS AND HAEMOSTASIS 2(8):1236-1237 Giangrande PLF Gene therapy for hemophilia? No | 0 | 0 |
| 114 | 1 | 19 | 87 2004 LANCET 364(9452):2181-2187 Gaspar HB; Parsley KL; Howe S; King D; Gilmour KC; et al. Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector | 0 | 0 |
| 115 | 1 | 75 | 88 2004 LANCET ONCOLOGY 5(8):469-479 Foley R; Lawler M; Hollywood D Gene-based therapy in prostate cancer | 0 | 0 |
| 116 | 1 | 42 | 95 2004 MOLECULAR THERAPY 9(4):548-556 Kankkonen HM; Vahakangas E; Marr RA; Pakkanen T; Laurema A; et al. Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy | 0 | 0 |
| 117 | 1 | 38 | 96 2004 MOLECULAR THERAPY 10(1):27-36 Yao SY; Sukonnik T; Kean T; Bharadwaj RR; Pasceri P; et al. Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications | 0 | 0 |
| 118 | 6 | 195 | 98 2004 MOLECULAR THERAPY 10(3):417-431 Horn PA; Morris JC; Neff T; Kiem HP Stem cell gene transfer-efficacy and safety in large animal studies | 0 | 0 |
| 119 | 1 | 28 | 99 2004 MOLECULAR THERAPY 10(3):469-477 Ueda K; Hanazono Y; Shibata H; Ageyama N; Ueda Y; et al. High-level in vivo gene marking after gene-modified autologous hematopoietic stem cell transplantation without marrow conditioning in nonhuman primates | 0 | 0 |
| 120 | 1 | 34 | 100 2004 MOLECULAR THERAPY 10(4):660-670 Recchia A; Perani L; Sartori D; Olgiati C; Mavilio F Site-specific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 1 | 29 | 101 2004 MOLECULAR THERAPY 10(5):862-873 Milsom MD; Woolford LB; Margison GP; Hurnphries RK; Fairbairn LJ Enhanced in vivo selection of bone marrow cells by retroviral-mediated coexpression of mutant O-6-methylguanine-DNA-methyltransferase and HOXB4 | 0 | 0 |
| 122 | 1 | 45 | 102 2004 MOLECULAR THERAPY 10(5):874-881 Laufs S; Nagy KZ; Giordano FA; Hotz-Wagenblatt A; Zeller WJ; et al. Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns | 0 | 0 |
| 123 | 2 | 52 | 103 2004 MOLECULAR THERAPY 10(5):892-902 Moayeri M; Ramezani A; Morgan RA; Hawley TS; Hawley RG Sustained phenotypic correction of hemophilia A mice following oncoretroviral-mediated expression of a bioengineered human factor VIII gene in long-term hematopoietic repopulating cells | 0 | 0 |
| 124 | 1 | 14 | 105 2004 NATURE BIOTECHNOLOGY 22(7):804-805 Salim A; Giaccia AJ; Longaker MT Stem cell differentiation | 0 | 0 |
| 125 | 1 | 2 | 106 2004 NATURE MEDICINE 10(1):8-8 [Anon] 'Bubble boy' trial delivers blow to gene therapy | 0 | 0 |
| 126 | 2 | 299 | 108 2004 NATURE MEDICINE 10(12):1307-1320 Germain RN An innately interesting decade of research in immunology | 0 | 0 |
| 127 | 1 | 96 | 110 2004 NATURE REVIEWS IMMUNOLOGY 4(11):878-888 Sorrentino BP Clinical strategies for expansion of haematopoietic stem cells | 0 | 0 |
| 128 | 2 | 25 | 111 2004 NEUROLOGY 63(12):2225-2232 Mendell JR; Miller A Gene transfer for neurologic disease - Agencies, policies, and process | 0 | 0 |
| 129 | 1 | 158 | 115 2004 POSTGRADUATE MEDICAL JOURNAL 80(948):560-570 Selkirk SM Gene therapy in clinical medicine | 0 | 0 |
| 130 | 1 | 10 | 116 2004 PRESSE MEDICALE 33:53-55 Kahn A From genomics to treatment | 0 | 0 |
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| 131 | 2 | 32 | 118 2004 REVISTA DE INVESTIGACION CLINICA 56(4):554-560 Lisker R Genomic medicine. Myths and reality | 0 | 0 |
| 132 | 2 | 122 | 122 2004 SEMINARS IN HEMATOLOGY 41(4):257-271 Larochelle A; Dunbar CE Genetic manipulation of hematopoietic stem cells | 0 | 0 |
| 133 | 6 | 138 | 125 2004 SEMINARS IN HEMATOLOGY 41(4):303-318 von Kalle C; Fehse B; Layh-Schmitt G; Schmidt M; Kelly P; et al. Stem cell clonality and genotoxicity in hematopoietic cells: Gene activation side effects should be avoidable | 0 | 0 |
| 134 | 1 | 31 | 126 2004 STEM CELLS 22(4):570-579 Nagy KZ; Laufs S; Gentner B; Naundorf S; Kuehlcke K; et al. Clonal analysis of individual marrow-repopulating cells after experimental peripheral blood progenitor cell transplantation | 0 | 0 |
| 135 | 2 | 125 | 128 2004 TECHNOLOGY IN CANCER RESEARCH & TREATMENT 3(5):479-490 Shinohara ET; Lu B; Hallahan DE The use of gene therapy in cancer research and treatment | 0 | 0 |
| 136 | 5 | 40 | 131 2004 TRENDS IN BIOTECHNOLOGY 22(11):560-563 Ashcroft RE Gene therapy in the clinic: whose risks? | 0 | 0 |
| 137 | 1 | 85 | 134 2005 ANNALS OF MEDICINE 37(1):33-43 Kanerva A; Hemminki A Adenoviruses for treatment of cancer | 0 | 0 |
| 138 | 1 | 37 | 135 2005 ANNUAL REVIEW OF MEDICINE 56:157-171 Schrier SL; Angelucci E New strategies in the treatment of the thalassemias | 0 | 0 |
| 139 | 1 | 114 | 136 2005 ANNUAL REVIEW OF MEDICINE 56:401-423 Dykxhoorn DM; Lieberman J The silent revolution: RNA interference as basic biology, research tool, and therapeutic | 0 | 0 |
| 140 | 4 | 68 | 137 2005 ANNUAL REVIEW OF MEDICINE 56:555-+ Nimjee SM; Rusconi CP; Sullenger BA Aptamers: An emerging class of therapeutics | 0 | 0 |
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| 141 | 1 | 35 | 138 2005 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 328(4):937-943 Borgnon J; Djamouri F; Lorand I; Di Rico V; Loux N; et al. Follistatin allows efficient retroviral-mediated gene transfer into rat liver | 0 | 0 |
| 142 | 1 | 43 | 139 2005 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 329(2):646-652 Chen ZYJ; Kren BT; Wong PYP; Low WC; Steer CJ Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference | 0 | 0 |
| 143 | 4 | 41 | 140 2005 BLOOD 105(3):997-1002 Neff T; Beard BC; Peterson LJ; Anandakumar P; Thompson J; et al. Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy | 0 | 0 |
| 144 | 4 | 101 | 141 2005 BRITISH JOURNAL OF HAEMATOLOGY 128(1):3-17 Nathwani AC; Davidoff AM; Linch DC A review of gene therapy for haematological disorders | 0 | 0 |
| 145 | 1 | 37 | 143 2005 CANCER GENE THERAPY 12(3):248-256 Smith PG; Burchill SA; Brooke D; Coletta PL; Whitehouse A Efficient infection and persistence of a herpesvirus saimiri-based gene delivery vector into human tumor xenografts and multicellular spheroid cultures | 0 | 0 |
| 146 | 1 | 70 | 144 2005 CURRENT GENE THERAPY 5(1):63-70 Sanz L; Qiao J; Vile RG; Alvarez-Vallina L Antibody engineering, virus retargeting and cellular immunotherapy: One ring to rule them all? | 0 | 0 |
| 147 | 2 | 104 | 145 2005 CURRENT GENE THERAPY 5(1):71-80 Chen Q; He Y; Yang KY Gene therapy for Parkinson's disease: Progress and challenges | 0 | 0 |
| 148 | 1 | 69 | 146 2005 CURRENT GENE THERAPY 5(1):121-132 Qasim W; Gaspar HB; Thrasher AJ T cell suicide gene therapy to aid haematopoietic stem cell transplantation | 0 | 0 |
| 149 | 2 | 87 | 147 2005 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 8(2):199-206 Herzog RW Recent advances in hepatic gene transfer: More efficacy and less immunogenicity | 0 | 0 |
| 150 | 3 | 68 | 148 2005 CURRENT OPINION IN MOLECULAR THERAPEUTICS 7(1):48-55 Thistlethwaite F; Mansoor W; Gilham DE; Hawkins RE Engineering T-cells with antibody-based chimeric receptors for effective cancer therapy | 0 | 0 |
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| 151 | 1 | 72 | 149 2005 EMBO JOURNAL 24(1):73-84 Chamorro MN; Schwartz DR; Vonica A; Brivanlou AH; Cho KR; et al. FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development | 0 | 0 |
| 152 | 1 | 43 | 150 2005 EXPERIMENTAL PHYSIOLOGY 90(1):27-31 Baker AH; Kritz A; Work LM; Nicklin SA; Nicklin A Cell-selective viral gene delivery vectors for the vasculature | 0 | 0 |
| 153 | 2 | 89 | 151 2005 EXPERT OPINION ON BIOLOGICAL THERAPY 5(1):33-53 Ewert KK; Ahmad A; Evans HM; Safinya CR Cationic lipid-DNA complexes for non-viral gene therapy: relating supramolecular structures to cellular pathways | 0 | 0 |
| 154 | 1 | 37 | 152 2005 GENE THERAPY 12(4):311-319 Zhao Y; Azam S; Thorpe R Comparative studies on cellular gene regulation by HIV-1 based vectors: implications for quality control of vector production | 0 | 0 |
| 155 | 2 | 37 | 153 2005 HUMAN GENE THERAPY 16(1):17-25 Manilla P; Rebello T; Afable C; Lu XB; Slepushkin V; et al. Regulatory considerations for novel gene therapy products: A review of the process leading to the first clinical lentiviral vector | 0 | 0 |
| 156 | 6 | 83 | 154 2005 IMMUNOLOGICAL REVIEWS 203:98-109 Fischer A; Le Deist F; Hacein-Bey-Abina S; Andre-Schmutz I; Basile GD; et al. Severe combined immunodeficiency. A model disease for molecular immunology and therapy | 0 | 0 |
| 157 | 1 | 179 | 155 2005 IMMUNOLOGICAL REVIEWS 203:216-234 Conley ME; Broides A; Hernandez-Trujillo V; Howard V; Kanegane H; et al. Genetic analysis of patients with defects in early B-cell development | 0 | 0 |
| 158 | 1 | 31 | 156 2005 JOURNAL OF CONTROLLED RELEASE 103(1):199-207 Nagasaki T; Kawazu T; Tachibana T; Tamagaki S; Shinkai S Enhanced nuclear import and transfection efficiency of plasmid DNA using streptavidin-fused importin-beta | 0 | 0 |
| 159 | 1 | 28 | 157 2005 JOURNAL OF CONTROLLED RELEASE 103(1):273-283 Chen DJ; Majors BS; Zelikin A; Putnam D Structure-function relationships of gene delivery vectors in a limited polycation library | 0 | 0 |
| 160 | 1 | 50 | 158 2005 JOURNAL OF GENE MEDICINE 7(2):137-144 Bryder D; Bjorgvinsdottir H; Sasaki Y; Jacobsen SEW Deficiency of oncoretrovirally transduced hematopoietic stem cells and correction through ex vivo expansion | 0 | 0 |
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| 161 | 2 | 6 | 159 2005 JOURNAL OF GENE MEDICINE 7(2):256-259 Bleijs DA Workshop on shedding data from gene therapy studies with viral vectors. Amsterdam, January 22, 2004 | 0 | 0 |
| 162 | 1 | 42 | 160 2005 JOURNAL OF SURGICAL RESEARCH 123(1):55-66 Conklin LD; McAninch RE; Schulz D; Kaluza GL; LeMaire SA; et al. HIV-based vectors and angiogenesis following rabbit hindlimb ischernial | 0 | 0 |
| 163 | 1 | 31 | 161 2005 JOURNAL OF VIROLOGICAL METHODS 123(1):65-72 Muller L; Saydam O; Saeki Y; Heid I; Fraefel C Gene transfer into hepatocytes mediated by herpes simplex virus-Epstein-Baff virus hybrid amplicons | 0 | 0 |
| 164 | 1 | 32 | 162 2005 JOURNAL OF VIROLOGY 79(6):3606-3614 Nakai H; Wu XL; Fuess S; Storm TA; Munroe D; et al. Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver | 0 | 0 |
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| 166 | 1 | 42 | 164 2005 LEUKEMIA RESEARCH 29(1):89-97 Hammond SM; Crable SC; Anderson KP Negative regulatory elements are present in the human LMO2 oncogene and may contribute to its expression in leukemia | 0 | 0 |
| 167 | 1 | 27 | 165 2005 LEUKEMIA RESEARCH 29(3):301-306 Schirrmann T; Pecher G Specific targeting of CD33(+) leukemia cells by a natural killer cell line modified with a chimeric receptor | 0 | 0 |
| 168 | 3 | 63 | 166 2005 MOLECULAR AND CELLULAR BIOLOGY 25(6):2085-2094 Yant SR; Wu XL; Huang Y; Garrison B; Burgess SM; et al. High-resolution genome-wide mapping of transposon integration in mammals | 0 | 0 |
| 169 | 1 | 50 | 167 2005 MOLECULAR AND CELLULAR NEUROSCIENCE 28(2):205-214 Lee SK; Jurata LW; Nowak R; Lettieri K; Kenny DA; et al. The LIM domain-only protein LM04 is required for neural tube closure | 0 | 0 |
| 170 | 3 | 50 | 168 2005 MOLECULAR THERAPY 11(1):35-47 Liu YL; Xu LF; Hennig AK; Kovacs A; Fu A; et al. Liver-directed neonatal gene therapy prevents cardiac, bone, ear, and eye disease in mucopolysaccharidosis I mice | 0 | 0 |
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| 171 | 2 | 69 | 170 2005 PEDIATRIC NEPHROLOGY 20(2):118-124 Worgall S A realistic chance for gene therapy in the near future | 0 | 0 |
| 172 | 1 | 131 | 171 2005 PEDIATRIC RESEARCH 57(3):458-467 Stiehm ER; Johnston RB A history of pediatric immunology | 0 | 0 |
| 173 | 1 | 10 | 172 2005 PLOS MEDICINE 2(1):22-24 Fischer A; Cavazzana-Calvo M Integration of retroviruses: A fine balance between efficiency and danger | 0 | 0 |
| 174 | 3 | 20 | 173 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(5):1275-1276 Engelman A The ups and downs of gene expression and retroviral DNA integration | 0 | 0 |
| 175 | 3 | 60 | 175 2005 TRENDS IN BIOTECHNOLOGY 23(1):42-47 Wiznerowicz M; Trono D Harnessing HIV for therapy, basic research and biotechnology | 0 | 0 |
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