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Wed Mar 30 12:14:50 2005
LMO2-associated clonal T cell proliferation in
two patients after gene therapy for SCID-X1

HACEIN-BEY-ABINA S, VON KALLE C, SCHMIDT M, et al.
SCIENCE 302: 415-419 2003
and the citing papers

Nodes: 175, Authors: 686, Journals: 90, Outer References: 7930, Words: 670
Collection span: 2003 - 2005
View: Overview. Sorted by journal name.
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
11646 2004 AIDS REVIEWS 6(1):13-21
Cereseto A; Giacca M
Integration site selection by retroviruses
00
211087 2004 AIDS REVIEWS 6(4):199-207
Lehmann-Che J; Saib A
Early stages of HIV replication: How to hijack cellular functions for a successful infection
00
311348 2004 ANNALS OF MEDICINE 36(7):504-517
Boneva RS; Folks TM
Xenotransplantation and risks of zoonotic infections
02
4185134 2005 ANNALS OF MEDICINE 37(1):33-43
Kanerva A; Hemminki A
Adenoviruses for treatment of cancer
00
511109 2004 ANNUAL REVIEW OF GENETICS 38:819-845
McCarty DM; Young SM; Samulski RJ
Integration of adeno-associated virus (AAV) and recombinant AAV vectors
01
619710 2004 ANNUAL REVIEW OF IMMUNOLOGY 22:625-655
Buckley RH
Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution
17
7137135 2005 ANNUAL REVIEW OF MEDICINE 56:157-171
Schrier SL; Angelucci E
New strategies in the treatment of the thalassemias
00
81114136 2005 ANNUAL REVIEW OF MEDICINE 56:401-423
Dykxhoorn DM; Lieberman J
The silent revolution: RNA interference as basic biology, research tool, and therapeutic
00
9468137 2005 ANNUAL REVIEW OF MEDICINE 56:555-+
Nimjee SM; Rusconi CP; Sullenger BA
Aptamers: An emerging class of therapeutics
00
1074911 2004 BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY 17(3):493-503
Li ZX; Modlich U; Baum C
Safety and efficacy in retrovirally modified haematopoietic cell therapy
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
1145712 2004 BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY 17(3):505-516
Aiuti A
Gene therapy for adenosine-deaminase-deficient severe combined immunodeficiency
00
12110013 2004 BEST PRACTICE & RESEARCH IN CLINICAL OBSTETRICS & GYNAECOLOGY 18(6):853-875
O'Donoghue K; Fisk NM
Fetal stem cells
00
1313314 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 320(3):998-1006
Condiotti R; Curran MA; Nolan GP; Giladi H; Ketzinel-Gilad M; et al.
Prolonged liver-specific transgene expression by a non-primate lentiviral vector
00
14135138 2005 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 328(4):937-943
Borgnon J; Djamouri F; Lorand I; Di Rico V; Loux N; et al.
Follistatin allows efficient retroviral-mediated gene transfer into rat liver
00
15143139 2005 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 329(2):646-652
Chen ZYJ; Kren BT; Wong PYP; Low WC; Steer CJ
Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference
00
16121315 2004 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1704(1):11-35
Dermine S; Gilham DE; Shaw DM; Davidson EJ; Meziane EK; et al.
Vaccine and antibody-directed T cell tumour immunotherapy
01
1722416 2004 BIOLOGY OF REPRODUCTION 71(2):405-409
Hofmann A; Zakhartchenko V; Weppert M; Sebald H; Wenigerkind H; et al.
Generation of transgenic cattle by lentiviral gene transfer into oocytes
13
18111617 2004 BIOLOGY OF THE CELL 96(4):261-269
Delyfer MN; Leveillard T; Mohand-Said S; Hicks D; Picaud S; et al.
Inherited retinal degenerations: therapeutic prospects
01
191611 2003 BIOTECHNIQUES 35(6):1273-+
Spangrude GJ
Future challenges for hematopoietic stem cell research
00
201318 2004 BLOOD 103(2):373-374
Rosenzweig M
Added challenges to gene therapy - immune responses in the setting of myeloablation
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
2128019 2004 BLOOD 103(11):4062-4069
Hanawa H; Hematti P; Keyvanfar K; Metzger ME; Krouse A; et al.
Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus-based lentiviral vector system
36
2224520 2004 BLOOD 103(11):4070-4077
Kuramoto K; Follmann DA; Hematti P; Sellers S; Agricola BA; et al.
Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates
23
2313721 2004 BLOOD 104(2):356-363
Soda Y; Tani K; Bal Y; Saiki M; Chen M; et al.
A novel maxizyme vector targeting a bcr-abl fusion gene induced specific cell death in Philadelphia chromosome-positive acute lymphoblastic leukemia
01
241222 2004 BLOOD 104(11):86A-86A
Schwarzwaelder K; Schmidt M; Howe S; Prinz C; Wissler M; et al.
Sustained polyclonal hematopoietic repopulation after successful SCID-X1 gene therapy by means of a non random integrating pseudotyped gammaretrovector
00
251523 2004 BLOOD 104(12):3419-3419
Sorrentino BP
One step closer to gene therapy for hemoglobinopathies
00
2624124 2004 BLOOD 104(12):3445-3453
Puthenveetil G; Scholes J; Carbonell D; Oureshi N; Xia P; et al.
Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector
00
2713325 2004 BLOOD 104(12):3543-3549
Frank O; Rudolph C; Heberlein C; von Neuhoff N; Schrock E; et al.
Tumor cells escape suicide gene therapy by genetic and epigenetic instability
00
28441140 2005 BLOOD 105(3):997-1002
Neff T; Beard BC; Peterson LJ; Anandakumar P; Thompson J; et al.
Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy
00
2918526 2004 BRITISH JOURNAL OF HAEMATOLOGY 126(1):3-10
Izraeli S
Leukaemia - a developmental perspective
02
304101141 2005 BRITISH JOURNAL OF HAEMATOLOGY 128(1):3-17
Nathwani AC; Davidoff AM; Linch DC
A review of gene therapy for haematological disorders
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
3121127 2004 BRITISH MEDICAL JOURNAL 329(7470):839-842
Relph K; Harrington K; Pandha H
Recent developments and current status of gene therapy using viral vectors in the United Kingdom
00
32120142 2005 BRITISH MEDICAL JOURNAL 330(7482):79-82
Kimmelman J
Recent developments in gene transfer: risk and ethics
01
331428 2004 CANADIAN MEDICAL ASSOCIATION JOURNAL 170(12):1785-1786
Johnston J; Baylis F
Gene therapy: two steps forward, one step back
00
34110929 2004 CANCER BIOLOGY & THERAPY 3(1):13-20
Lin YW; Aplan PD
Leukemic transformation
00
3521330 2004 CANCER CELL 5(3):203-204
Braun BS; Shannon K
The sum is greater than the FGFR1 partner
00
36137143 2005 CANCER GENE THERAPY 12(3):248-256
Smith PG; Burchill SA; Brooke D; Coletta PL; Whitehouse A
Efficient infection and persistence of a herpesvirus saimiri-based gene delivery vector into human tumor xenografts and multicellular spheroid cultures
00
3717431 2004 CARDIOVASCULAR RESEARCH 64(2):208-216
Sharif F; Daly K; Crowley J; O'Brien T
Current status of catheter-and stent-based gene therapy
00
38122432 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(18):2361-2385
Orange JS; Stone KD; Turvey SE; Krzewski K
The Wiskott-Aldrich syndrome
00
3916633 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(19-20):2588-2596
Wu X; Burgess SM
Integration target site selection for retroviruses and transposable elements
00
4014734 2004 CIRCULATION 110(21):3378-3383
Frangioni JV; Hajjar RJ
In vivo tracking of stem cells for clinical trials in cardiovascular disease
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
4115135 2004 CLINICAL IMMUNOLOGY 111(3):262-274
Bernstein WB; Cox JH; Aronson NE; Tracy LR; Schlienger K; et al.
Immune reconstitution following autologous transfers of CD3/CD28 stimulated CD4(+) T cells to HIV-infected persons
02
42123036 2004 CRITICAL REVIEWS IN IMMUNOLOGY 24(2):87-110
Nagy ZS; Ross J; Cheng HY; Stepkowski SM; Kirken RA
Regulation of lymphoid cell apoptosis by Jaks and Stats
00
43112837 2004 CURRENT GENE THERAPY 4(3):263-276
Haviernik P; Bunting KD
Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors
00
44170144 2005 CURRENT GENE THERAPY 5(1):63-70
Sanz L; Qiao J; Vile RG; Alvarez-Vallina L
Antibody engineering, virus retargeting and cellular immunotherapy: One ring to rule them all?
00
452104145 2005 CURRENT GENE THERAPY 5(1):71-80
Chen Q; He Y; Yang KY
Gene therapy for Parkinson's disease: Progress and challenges
00
46169146 2005 CURRENT GENE THERAPY 5(1):121-132
Qasim W; Gaspar HB; Thrasher AJ
T cell suicide gene therapy to aid haematopoietic stem cell transplantation
00
4725838 2004 CURRENT OPINION IN BIOTECHNOLOGY 15(5):383-391
Weber W; Fussenegger M
Approaches for trigger-inducible viral transgene regulation in geno-based tissue engineering
01
4836039 2004 CURRENT OPINION IN CELL BIOLOGY 16(6):713-720
Mayhall EA; Paffett-Lugassy N; Zon LI
The clinical potential of stem cells
00
49287147 2005 CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT 8(2):199-206
Herzog RW
Recent advances in hepatic gene transfer: More efficacy and less immunogenicity
00
5028140 2004 CURRENT OPINION IN INFECTIOUS DISEASES 17(1):17-26
Whitney JB; Ruprecht RM
Live attenuated HIV vaccines: pitfalls and prospects
02
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
5161141 2004 CURRENT OPINION IN MOLECULAR THERAPEUTICS 6(4):358-359
Gunzburg WH
Editorial overview - A milestone year for gene therapy goes unnoticed
00
52368148 2005 CURRENT OPINION IN MOLECULAR THERAPEUTICS 7(1):48-55
Thistlethwaite F; Mansoor W; Gilham DE; Hawkins RE
Engineering T-cells with antibody-based chimeric receptors for effective cancer therapy
00
5325142 2004 CYTOGENETIC AND GENOME RESEARCH 105(2-4):435-441
Sangiuolo F; Novelli G
Sequence-specific modification of mouse genomic DNA mediated by gene targeting techniques
01
5415843 2004 EMBO JOURNAL 23(18):3589-3598
Deane JE; Ryan DP; Sunde M; Maher MJ; Guss JM; et al.
Tandem LIM domains provide synergistic binding in the LMO4 : Ldb1 complex
01
55172149 2005 EMBO JOURNAL 24(1):73-84
Chamorro MN; Schwartz DR; Vonica A; Brivanlou AH; Cho KR; et al.
FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development
00
5614544 2004 EXPERIMENTAL CELL RESEARCH 298(2):611-623
Jakobsson J; Rosenqvist N; Thompson L; Barraud P; Lundberg C
Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator
00
57143150 2005 EXPERIMENTAL PHYSIOLOGY 90(1):27-31
Baker AH; Kritz A; Work LM; Nicklin SA; Nicklin A
Cell-selective viral gene delivery vectors for the vasculature
00
58117345 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(5):631-644
Audet J
Stem cell bioengineering for regenerative medicine
02
59124346 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(7):1073-1091
Prieto J; Qian C; Hernandez-Alcoceba R; Gonzalez-Aseguinolaza G; Mazzolini G; et al.
Gene therapy of liver diseases
00
6026447 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(9):1403-1412
Prasmickaite L; Hogset A; Engesaeter BO; Bonsted A; Berg K
Light-directed gene delivery by photochemical internalisation
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#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
61212648 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(9):1423-1434
Barese CN; Goebel WS; Dinauer MC
Gene therapy for chronic granulomatous disease
00
6226449 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(9):1435-1443
Bauer JW; Laimer M
Gene therapy of epidermolysis bullosa
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6317150 2004 EXPERT OPINION ON BIOLOGICAL THERAPY 4(12):1921-1929
Borkhardt A; Heidenreich O
RNA interference as a potential tool in the treatment of leukaemia
00
64289151 2005 EXPERT OPINION ON BIOLOGICAL THERAPY 5(1):33-53
Ewert KK; Ahmad A; Evans HM; Safinya CR
Cationic lipid-DNA complexes for non-viral gene therapy: relating supramolecular structures to cellular pathways
00
6545451 2004 GENE THERAPY 11:S3-S9
Barquinero J; Eixarch H; Perez-Melgosa M
Retroviral vectors: new applications for an old tool
00
6614952 2004 GENE THERAPY 11:S57-S63
Del Rio M; Gache Y; Jorcano JL; Meneguzzi G; Larcher F
Current approaches and perspectives in human keratinocyte-based gene therapies
00
67110553 2004 GENE THERAPY 11:S76-S84
Nguyen TH; Ferry N
Liver gene therapy: advances and hurdles
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6822654 2004 GENE THERAPY 11(7):569-573
Sadelain M
Insertional oncogenesis in gene therapy: how much of a risk?
12
6921455 2004 GENE THERAPY 11(11):879-881
Fehse B; Kustikova OS; Bubenheim M; Baum C
Pois(s)on - It's a question of dose ...
11
7014956 2004 GENE THERAPY 11(21):1568-1578
Kraunus J; Schaumann DHS; Meyer J; Modlich U; Fehse B; et al.
Self-inactivating retroviral vectors with improved RNA processing
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
71137152 2005 GENE THERAPY 12(4):311-319
Zhao Y; Azam S; Thorpe R
Comparative studies on cellular gene regulation by HIV-1 based vectors: implications for quality control of vector production
00
7221257 2004 GENOME BIOLOGY 5(8)
Qiao J; Diaz RM; Vile RG
Success for gene therapy: render unto Caesar that which is Caesar's
00
7311558 2004 HAEMATOLOGICA 89(7):774-776
Mannucci PM; Bonomi AB
The future of hemophilia treatment
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7412759 2004 HAEMOPHILIA 10:47-54
Farrugia A; Manno CS; Evatt BL
Emerging and receding risks of therapeutic regimens for haemophilia
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7525060 2004 HAEMOPHILIA 10(4):309-318
Nathwani AC; Davidoff AM; Tuddenham EGD
Prospects for gene therapy of haemophilia
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7618661 2004 HEMATOLOGY JOURNAL 5(2):103-111
Klein C; Baum C
Gene therapy for inherited disorders of haematopoietic cells
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7713062 2004 HUMAN GENE THERAPY 15(5):457-468
Qiao RL; Zhou BY; Harboe-Schmidt E; Kasahara N; Kim KJ; et al.
Subunit-specific coordinate upregulation of sodium pump activity in alveolar epithelial cells by lentivirus-mediated gene transfer
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7815063 2004 HUMAN GENE THERAPY 15(8):758-769
Chinnasamy D; Fairbairn LJ; Neuenfeldt J; Treisman JS; Hanson JP; et al.
Lentivirus-mediated expression of mutant MGMT(P140K) protects human CD34(+) cells against the combined toxicity of O-6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide
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7925564 2004 HUMAN GENE THERAPY 15(11):1131-1154
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Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis
00
80237153 2005 HUMAN GENE THERAPY 16(1):17-25
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00
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81683154 2005 IMMUNOLOGICAL REVIEWS 203:98-109
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Severe combined immunodeficiency. A model disease for molecular immunology and therapy
00
821179155 2005 IMMUNOLOGICAL REVIEWS 203:216-234
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Genetic analysis of patients with defects in early B-cell development
00
8311365 2004 INTERNAL MEDICINE JOURNAL 34(11):621-625
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841122 2003 ISRAEL MEDICAL ASSOCIATION JOURNAL 5(12):883-884
Etzioni A
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85113 2003 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 290(19):2535-2535
[Anon]
Gene therapy-leukemia link
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8618566 2004 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 113(4):595-603
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8722467 2004 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 113(4):607-609
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Primary immunodeficiency: Looking backwards, looking forwards
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8815468 2004 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 114(2):398-405
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Advances in asthma, allergy and immunology series 2004: Basic and clinical immunology
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8932469 2004 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 114(2):406-408
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Importance of technology for the future of allergy and immunology
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9015970 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(47):48883-48892
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Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase
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91110971 2004 JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS 18(1):62-71
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Genetic modification of T cells for cancer therapy
11
92114572 2004 JOURNAL OF BIOMEDICAL SCIENCE 11(4):439-449
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Lentiviral vectors
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9332273 2004 JOURNAL OF CLINICAL INVESTIGATION 114(7):889-891
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9417374 2004 JOURNAL OF CLINICAL INVESTIGATION 114(7):953-962
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High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells
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Enhancer-deleted retroviral vectors restore high levels of superoxide generation in a mouse model of CGD
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Safe two-plasmid production for the first clinical lentivirus vector that achieves > 99% transduction in primary cells using a one-step protocol
01
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10115079 2004 JOURNAL OF GENE MEDICINE 6(11):1257-1271
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Unmodified oligodeoxynucleotides require single-strandedness to induce targeted repair of a chromosomal EGFP gene
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102150158 2005 JOURNAL OF GENE MEDICINE 7(2):137-144
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Deficiency of oncoretrovirally transduced hematopoietic stem cells and correction through ex vivo expansion
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10514781 2004 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 36(3):333-341
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Feline immunodeficiency virus and retrovirus-mediated adventitial ex vivo gene transfer to rabbit carotid artery using autologous vascular smooth muscle cells
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Gene therapy for hemophilia? No
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Efficacy of gene therapy for SCID is being confirmed
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Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
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Overexpression of HOXB4 confers a myelo-erythroid differentiation delay in vitro
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Negative regulatory elements are present in the human LMO2 oncogene and may contribute to its expression in leukemia
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118127165 2005 LEUKEMIA RESEARCH 29(3):301-306
Schirrmann T; Pecher G
Specific targeting of CD33(+) leukemia cells by a natural killer cell line modified with a chimeric receptor
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11911089 2004 M S-MEDECINE SCIENCES 20(1):115-117
Fischer A; Hacein-Bey-Abina S; Cavazzana-Calvo M
Gene therapy of children with X-linked severe combined immune deficiency : efficiency and comlications
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The LIM domain-only protein LM04 is required for neural tube closure
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12215890 2004 MOLECULAR CELL 13(3):403-414
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The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces
04
12313291 2004 MOLECULAR GENETICS AND METABOLISM 82(1):4-19
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Neonatal retroviral vector-mediated hepatic gene therapy reduces bone, joint, and cartilage disease in mucopolysaccharidosis VII mice and dogs
22
12415492 2004 MOLECULAR THERAPY 9(1):5-13
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Chance or necessity? Insertional mutagenesis in gene therapy and its consequences
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12518193 2004 MOLECULAR THERAPY 9(2):147-156
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