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Nodes: 4913,
Authors: 11522,
Journals: 1289,
Outer References: 158983,
Words: 7709
Collection span: 1942 - 2005
View: Overview. Sorted by LCS.
Page 1: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 0 | 16 | 29 1956 JOURNALS OF GERONTOLOGY 11(3):298-300 HARMAN D AGING - A THEORY BASED ON FREE-RADICAL AND RADIATION-CHEMISTRY | 1257 | 1257 |
| 2 | 25 | 100 | 613 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78(11):7124-7128 HARMAN D THE AGING PROCESS | 964 | 966 |
| 3 | 14 | 195 | 974 1987 ANNALS OF INTERNAL MEDICINE 107(4):526-545 CROSS CE; HALLIWELL B; BORISH ET; PRYOR WA; AMES BN; et al. OXYGEN RADICALS AND HUMAN-DISEASE | 913 | 918 |
| 4 | 4 | 590 | 511 1979 PHYSIOLOGICAL REVIEWS 59(3):527-605 CHANCE B; SIES H; BOVERIS A HYDROPEROXIDE METABOLISM IN MAMMALIAN ORGANS | 295 | 2725 |
| 5 | 5 | 34 | 144 1968 JOURNALS OF GERONTOLOGY 23(4):476-& HARMAN D FREE RADICAL THEORY OF AGING - EFFECT OF FREE RADICAL REACTION INHIBITORS ON MORTALITY RATE OF MALE LAF1 MICE | 275 | 275 |
| 6 | 21 | 216 | 2001 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(17):7915-7922 AMES BN; SHIGENAGA MK; HAGEN TM OXIDANTS, ANTIOXIDANTS, AND THE DEGENERATIVE DISEASES OF AGING | 265 | 1873 |
| 7 | 9 | 26 | 2262 1994 SCIENCE 263(5150):1128-1130 ORR WC; SOHAL RS EXTENSION OF LIFE-SPAN BY OVEREXPRESSION OF SUPEROXIDE-DISMUTASE AND CATALASE IN DROSOPHILA-MELANOGASTER | 247 | 647 |
| 8 | 11 | 26 | 240 1972 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 20(4):145-& HARMAN D BIOLOGIC CLOCK - MITOCHONDRIA | 244 | 243 |
| 9 | 4 | 58 | 1781 1992 SCIENCE 257(5074):1220-1224 STADTMAN ER PROTEIN OXIDATION AND AGING | 243 | 1208 |
| 10 | 22 | 71 | 2776 1996 SCIENCE 273(5271):59-63 Sohal RS; Weindruch R Oxidative stress, caloric restriction, and aging | 224 | 833 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 37 | 115 | 1753 1992 MUTATION RESEARCH 275(3-6):257-266 HARMAN D FREE-RADICAL THEORY OF AGING | 215 | 215 |
| 12 | 116 | 406 | 3281 1998 PHYSIOLOGICAL REVIEWS 78(2):547-581 Beckman KB; Ames BN The free radical theory of aging matures | 200 | 644 |
| 13 | 5 | 294 | 742 1983 SCIENCE 221(4617):1256-1264 AMES BN DIETARY CARCINOGENS AND ANTICARCINOGENS - OXYGEN RADICALS AND DEGENERATIVE DISEASES | 190 | 1895 |
| 14 | 33 | 257 | 754 1984 AGE 7(4):111-131 HARMAN D FREE-RADICAL THEORY OF AGING - THE FREE-RADICAL DISEASES | 159 | 159 |
| 15 | 16 | 129 | 540 1980 EXPERIMENTAL GERONTOLOGY 15(6):575-591 MIQUEL J; ECONOMOS AC; FLEMING J; JOHNSON JE MITOCHONDRIAL ROLE IN CELL AGING | 147 | 269 |
| 16 | 30 | 114 | 688 1983 AGE 6(3):86-94 HARMAN D FREE-RADICAL THEORY OF AGING - CONSEQUENCES OF MITOCHONDRIAL AGING | 147 | 147 |
| 17 | 6 | 55 | 71 1962 RADIATION RESEARCH 16(5):753-& HARMAN D ROLE OF FREE RADICALS IN MUTATION, CANCER, AGING, AND MAINTENANCE OF LIFE | 140 | 140 |
| 18 | 3 | 33 | 466 1979 ANALYTICAL BIOCHEMISTRY 95(2):351-358 OHKAWA H; OHISHI N; YAGI K ASSAY FOR LIPID PEROXIDES IN ANIMAL-TISSUES BY THIOBARBITURIC ACID REACTION | 126 | 3735 |
| 19 | 11 | 81 | 159 1969 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 17(8):721-& HARMAN D PROLONGATION OF LIFE - ROLE OF FREE RADICAL REACTIONS IN AGING | 125 | 125 |
| 20 | 1 | 22 | 1568 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(9):3633-3636 CARNEY JM; STARKEREED PE; OLIVER CN; LANDUM RW; CHENG MS; et al. REVERSAL OF AGE-RELATED INCREASE IN BRAIN PROTEIN OXIDATION, DECREASE IN ENZYME-ACTIVITY, AND LOSS IN TEMPORAL AND SPATIAL MEMORY BY CHRONIC ADMINISTRATION OF THE SPIN-TRAPPING COMPOUND N-TERT-BUTYL-ALPHA-PHENYLNITRONE | 122 | 427 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 10 | 35 | 2187 1994 MECHANISMS OF AGEING AND DEVELOPMENT 74(1-2):121-133 SOHAL RS; KU HH; AGARWAL S; FORSTER MJ; LAL H OXIDATIVE DAMAGE, MITOCHONDRIAL OXIDANT GENERATION AND ANTIOXIDANT DEFENSES DURING AGING AND IN RESPONSE TO FOOD RESTRICTION IN THE MOUSE | 118 | 283 |
| 22 | 2 | 3 | 56 1961 JOURNALS OF GERONTOLOGY 16(3):247-254 HARMAN D PROLONGATION OF THE NORMAL LIFESPAN AND INHIBITION OF SPONTANEOUS CANCER BY ANTIOXIDANTS | 110 | 110 |
| 23 | 6 | 31 | 215 1971 JOURNALS OF GERONTOLOGY 26(4):451-& HARMAN D FREE RADICAL THEORY OF AGING - EFFECT OF AMOUNT AND DEGREE OF UNSATURATION OF DIETARY FAT ON MORTALITY RATE | 108 | 108 |
| 24 | 4 | 44 | 1391 1990 NUCLEIC ACIDS RESEARCH 18(23):6927-6933 CORTOPASSI GA; ARNHEIM N DETECTION OF A SPECIFIC MITOCHONDRIAL-DNA DELETION IN TISSUES OF OLDER HUMANS | 107 | 396 |
| 25 | 8 | 53 | 649 1982 GERONTOLOGY 28(1):44-53 FLEMING JE; MIQUEL J; COTTRELL SF; YENGOYAN LS; ECONOMOS AC IS CELL AGING CAUSED BY RESPIRATION-DEPENDENT INJURY TO THE MITOCHONDRIAL GENOME | 106 | 171 |
| 26 | 7 | 50 | 1399 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(12):4533-4537 FRAGA CG; SHIGENAGA MK; PARK JW; DEGAN P; AMES BN OXIDATIVE DAMAGE TO DNA DURING AGING - 8-HYDROXY-2'-DEOXYGUANOSINE IN RAT ORGAN DNA AND URINE | 100 | 554 |
| 27 | 30 | 126 | 2236 1994 PHARMACOLOGY OF AGING PROCESSES: METHODS OF ASSESSMENT AND POTENTIAL INTERVENTIONS 717:1-15 HARMAN D FREE-RADICAL THEORY OF AGING - INCREASING THE FUNCTIONAL LIFE-SPAN | 97 | 97 |
| 28 | 4 | 42 | 1571 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(23):10540-10543 SMITH CD; CARNEY JM; STARKEREED PE; OLIVER CN; STADTMAN ER; et al. EXCESS BRAIN PROTEIN OXIDATION AND ENZYME DYSFUNCTION IN NORMAL AGING AND IN ALZHEIMER-DISEASE | 90 | 548 |
| 29 | 50 | 218 | 1868 1993 DRUGS & AGING 3(1):60-80 HARMAN D FREE-RADICAL INVOLVEMENT IN AGING - PATHOPHYSIOLOGY AND THERAPEUTIC IMPLICATIONS | 88 | 87 |
| 30 | 6 | 18 | 216 1971 NATURE 229(5282):254-& COMFORT A; YOUHOTSK.I; PATHMANA.K EFFECT OF ETHOXYQUIN ON LONGEVITY OF C3H MICE | 87 | 111 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 12 | 50 | 1570 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(12):5360-5363 HARMAN D THE AGING PROCESS - MAJOR RISK FACTOR FOR DISEASE AND DEATH | 85 | 85 |
| 32 | 3 | 15 | 110 1965 JOURNALS OF GERONTOLOGY 20(2):151-153 HARMAN D THE FREE-RADICAL THEORY OF AGING - EFFECT OF AGE ON SERUM COPPER LEVELS | 84 | 84 |
| 33 | 5 | 36 | 271 1973 JOURNALS OF GERONTOLOGY 28(4):415-424 TAPPEL A; FLETCHER B; DEAMER D EFFECT OF ANTIOXIDANTS AND NUTRIENTS ON LIPID PEROXIDATION FLUORESCENT PRODUCTS AND AGING PARAMETERS IN MOUSE | 83 | 200 |
| 34 | 3 | 36 | 1775 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(16):7370-7374 CORTOPASSI GA; SHIBATA D; SOONG NW; ARNHEIM N A PATTERN OF ACCUMULATION OF A SOMATIC DELETION OF MITOCHONDRIAL-DNA IN AGING HUMAN TISSUES | 81 | 292 |
| 35 | 14 | 50 | 1025 1987 MECHANISMS OF AGEING AND DEVELOPMENT 41(1-2):125-137 SAWADA M; CARLSON JC CHANGES IN SUPEROXIDE RADICAL AND LIPID PEROXIDE FORMATION IN THE BRAIN, HEART AND LIVER DURING THE LIFETIME OF THE RAT | 80 | 134 |
| 36 | 13 | 23 | 1115 1988 MOLECULAR AND CELLULAR BIOCHEMISTRY 84(2):155-161 HARMAN D FREE-RADICALS IN AGING | 79 | 79 |
| 37 | 7 | 48 | 2002 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(19):8905-8909 LARSEN PL AGING AND RESISTANCE TO OXIDATIVE DAMAGE IN CAENORHABDITIS-ELEGANS | 77 | 267 |
| 38 | 7 | 18 | 3258 1998 NATURE GENETICS 19(2):171-174 Parkes TL; Elia AJ; Dickinson D; Hilliker AJ; Phillips JP; et al. Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons | 76 | 263 |
| 39 | 2 | 58 | 612 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78(11):6858-6862 AMES BN; CATHCART R; SCHWIERS E; HOCHSTEIN P URIC-ACID PROVIDES AN ANTIOXIDANT DEFENSE IN HUMANS AGAINST OXIDANT-CAUSED AND RADICAL-CAUSED AGING AND CANCER - A HYPOTHESIS | 74 | 797 |
| 40 | 11 | 103 | 547 1980 JOURNALS OF GERONTOLOGY 35(1):45-56 LEIBOVITZ BE; SIEGEL BV ASPECTS OF FREE-RADICAL REACTIONS IN BIOLOGICAL-SYSTEMS - AGING | 72 | 203 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 8 | 84 | 1496 1991 GERONTOLOGY 37(1-3):166-180 PACIFICI RE; DAVIES KJA PROTEIN, LIPID AND DNA-REPAIR SYSTEMS IN OXIDATIVE STRESS - THE FREE-RADICAL THEORY OF AGING REVISITED | 70 | 201 |
| 42 | 6 | 58 | 997 1987 JOURNAL OF NUTRITION 117(2):361-367 KOIZUMI A; WEINDRUCH R; WALFORD RL INFLUENCES OF DIETARY RESTRICTION AND AGE ON LIVER-ENZYME ACTIVITIES AND LIPID-PEROXIDATION IN MICE | 69 | 198 |
| 43 | 1 | 2 | 33 1957 JOURNALS OF GERONTOLOGY 12(3):257-263 HARMAN D PROLONGATION OF THE NORMAL LIFE-SPAN BY RADIATION PROTECTION CHEMICALS | 68 | 74 |
| 44 | 8 | 33 | 396 1977 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 25(9):400-407 HARMAN D; HEIDRICK ML; EDDY DE FREE-RADICAL THEORY OF AGING - EFFECT OF FREE-RADICAL-REACTION INHIBITORS ON IMMUNE-RESPONSE | 65 | 65 |
| 45 | 7 | 195 | 1107 1988 MAYO CLINIC PROCEEDINGS 63(4):390-408 SOUTHORN PA; POWIS G FREE-RADICALS IN MEDICINE .2. INVOLVEMENT IN HUMAN-DISEASE | 65 | 268 |
| 46 | 17 | 74 | 1438 1991 ARCHIVES OF GERONTOLOGY AND GERIATRICS 12(2-3):99-117 MIQUEL J AN INTEGRATED THEORY OF AGING AS THE RESULT OF MITOCHONDRIAL-DNA MUTATION IN DIFFERENTIATED CELLS | 64 | 116 |
| 47 | 7 | 41 | 1532 1991 MECHANISMS OF AGEING AND DEVELOPMENT 57(2):187-202 SOHAL RS; SOHAL BH HYDROGEN-PEROXIDE RELEASE BY MITOCHONDRIA INCREASES DURING AGING | 64 | 117 |
| 48 | 16 | 151 | 2726 1996 NATURE GENETICS 13(1):25-34 Martin GM; Austad SN; Johnson TE Genetic analysis of ageing: Role of oxidative damage and environmental stresses | 64 | 271 |
| 49 | 14 | 249 | 2247 1994 PHYSIOLOGICAL REVIEWS 74(1):139-162 YU BP CELLULAR DEFENSES AGAINST DAMAGE FROM REACTIVE OXYGEN SPECIES | 63 | 613 |
| 50 | 5 | 90 | 520 1980 AGE 3(3):64-73 HARMAN D FREE-RADICAL THEORY OF AGING - BENEFICIAL EFFECT OF ANTIOXIDANTS ON THE LIFE-SPAN OF MALE NZB MICE - ROLE OF FREE-RADICAL REACTIONS IN THE DETERIORATION OF THE IMMUNE-SYSTEM WITH AGE AND IN THE PATHOGENESIS OF SYSTEMIC LUPUS-ERYTHEMATOSUS | 62 | 62 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 6 | 50 | 944 1986 JOURNAL OF NEUROCHEMISTRY 46(5):1344-1352 MIZUNO Y; OHTA K REGIONAL DISTRIBUTIONS OF THIOBARBITURIC ACID-REACTIVE PRODUCTS, ACTIVITIES OF ENZYMES REGULATING THE METABOLISM OF OXYGEN FREE-RADICALS, AND SOME OF THE RELATED ENZYMES IN ADULT AND AGED RAT BRAINS | 62 | 122 |
| 52 | 10 | 161 | 1321 1990 EXPERIMENTAL GERONTOLOGY 25(6):499-522 SOHAL RS; ALLEN RG OXIDATIVE STRESS AS A CAUSAL FACTOR IN DIFFERENTIATION AND AGING - A UNIFYING HYPOTHESIS | 62 | 136 |
| 53 | 29 | 117 | 1610 1992 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 673:126-141 HARMAN D ROLE OF FREE-RADICALS IN AGING AND DISEASE | 62 | 62 |
| 54 | 1 | 35 | 32 1957 JOURNALS OF GERONTOLOGY 12(2):199-202 HARMAN D ATHEROSCLEROSIS - A HYPOTHESIS CONCERNING TH EINITIATING STEPS IN PATHOGENESIS | 61 | 61 |
| 55 | 1 | 3 | 214 1971 JOURNALS OF GERONTOLOGY 26(3):378-& KOHN RR EFFECT OF ANTIOXIDANTS ON LIFE-SPAN OF C57BL MICE | 61 | 74 |
| 56 | 4 | 32 | 1447 1991 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 178(1):124-131 YEN TC; SU JH; KING KL; WEI YH AGING-ASSOCIATED 5 KB DELETION IN HUMAN LIVER MITOCHONDRIAL-DNA | 61 | 167 |
| 57 | 1 | 17 | 425 1978 ANALYTICAL BIOCHEMISTRY 86(1):271-278 UCHIYAMA M; MIHARA M DETERMINATION OF MALONALDEHYDE PRECURSOR IN TISSUES BY THIOBARBITURIC ACID TEST | 60 | 1079 |
| 58 | 5 | 58 | 1702 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(1):166-172 CHENG KC; CAHILL DS; KASAI H; NISHIMURA S; LOEB LA 8-HYDROXYGUANINE, AN ABUNDANT FORM OF OXIDATIVE DNA DAMAGE, CAUSES G-]T AND A-]C SUBSTITUTIONS | 59 | 837 |
| 59 | 9 | 74 | 2381 1995 FASEB JOURNAL 9(7):526-533 REITER RJ OXIDATIVE PROCESSES AND ANTIOXIDATIVE DEFENSE-MECHANISMS IN THE AGING BRAIN | 57 | 370 |
| 60 | 2 | 23 | 1549 1991 NATURE 349(6308):431-434 SHIBUTANI S; TAKESHITA M; GROLLMAN AP INSERTION OF SPECIFIC BASES DURING DNA-SYNTHESIS PAST THE OXIDATION-DAMAGED BASE 8-OXODG | 56 | 1063 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 3 | 28 | 136 1968 GERIATRICS 23(10):97-& TAPPEL AL WILL ANTIOXIDANT NUTRIENTS SLOW AGING PROCESSES | 55 | 261 |
| 62 | 3 | 19 | 363 1976 JOURNALS OF GERONTOLOGY 31(4):405-408 KELLOGG EW; FRIDOVICH I SUPEROXIDE-DISMUTASE IN RAT AND MOUSE AS A FUNCTION OF AGE AND LONGEVITY | 55 | 114 |
| 63 | 4 | 17 | 119 1966 JOURNALS OF GERONTOLOGY 21(4):560-& HARMAN D; PIETTE LH FREE RADICAL THEORY OF AGING - FREE RADICAL REACTIONS IN SERUM | 54 | 54 |
| 64 | 9 | 34 | 2000 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(15):7255-7259 SOHAL RS; AGARWAL S; DUBEY A; ORR WC PROTEIN OXIDATIVE DAMAGE IS ASSOCIATED WITH LIFE EXPECTANCY OF HOUSEFLIES | 54 | 132 |
| 65 | 6 | 35 | 3019 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(7):3064-3069 Hagen TM; Yowe DL; Bartholomew JC; Wehr CM; Do KL; et al. Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase | 54 | 163 |
| 66 | 12 | 94 | 1086 1988 FEBS LETTERS 241(1-2):1-5 RICHTER C DO MITOCHONDRIAL-DNA FRAGMENTS PROMOTE CANCER AND AGING | 53 | 137 |
| 67 | 4 | 65 | 1150 1989 AMERICAN JOURNAL OF PATHOLOGY 134(5):1167-1173 MULLERHOCKER J CYTOCHROME-C-OXIDASE DEFICIENT CARDIOMYOCYTES IN THE HUMAN-HEART - AN AGE-RELATED PHENOMENON - A HISTOCHEMICAL ULTRACYTOCHEMICAL STUDY | 52 | 165 |
| 68 | 6 | 44 | 1761 1992 NATURE GENETICS 2(4):318-323 SOONG NW; HINTON DR; CORTOPASSI G; ARNHEIM N MOSAICISM FOR A SPECIFIC SOMATIC MITOCHONDRIAL-DNA MUTATION IN ADULT HUMAN BRAIN | 52 | 191 |
| 69 | 7 | 27 | 2133 1994 FREE RADICAL RESEARCH 21(5):317-327 BARJA G; CADENAS S; ROJAS C; PEREZCAMPO R; LOPEZTORRES M LOW MITOCHONDRIAL FREE-RADICAL PRODUCTION PER UNIT O-2 CONSUMPTION CAN EXPLAIN THE SIMULTANEOUS PRESENCE OF HIGH LONGEVITY AND HIGH AEROBIC METABOLIC-RATE IN BIRDS | 52 | 104 |
| 70 | 15 | 210 | 1296 1990 BIOLOGICAL REVIEWS OF THE CAMBRIDGE PHILOSOPHICAL SOCIETY 65(3):375-398 MEDVEDEV ZA AN ATTEMPT AT A RATIONAL CLASSIFICATION OF THEORIES OF AGING | 50 | 98 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 10 | 50 | 1368 1990 MECHANISMS OF AGEING AND DEVELOPMENT 53(1):49-60 RAO G; XIA E; RICHARDSON A EFFECT OF AGE ON THE EXPRESSION OF ANTIOXIDANT ENZYMES IN MALE FISCHER-F344 RATS | 50 | 104 |
| 72 | 11 | 260 | 695 1983 BIOCHIMICA ET BIOPHYSICA ACTA 726(1):41-80 HANSFORD RG BIOENERGETICS IN AGING | 49 | 167 |
| 73 | 3 | 19 | 1236 1989 MECHANISMS OF AGEING AND DEVELOPMENT 49(2):129-135 SOHAL RS; SVENSSON I; SOHAL BH; BRUNK UT SUPEROXIDE ANION RADICAL PRODUCTION IN DIFFERENT ANIMAL SPECIES | 49 | 85 |
| 74 | 1 | 86 | 1246 1989 NEW ENGLAND JOURNAL OF MEDICINE 320(6):365-376 WEISS SJ TISSUE DESTRUCTION BY NEUTROPHILS | 49 | 2768 |
| 75 | 4 | 35 | 1251 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86(8):2761-2765 PHILLIPS JP; CAMPBELL SD; MICHAUD D; CHARBONNEAU M; HILLIKER AJ NULL MUTATION OF COPPER-ZINC SUPEROXIDE-DISMUTASE IN DROSOPHILA CONFERS HYPERSENSITIVITY TO PARAQUAT AND REDUCED LONGEVITY | 48 | 171 |
| 76 | 4 | 32 | 1252 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86(16):6377-6381 FREI B; ENGLAND L; AMES BN ASCORBATE IS AN OUTSTANDING ANTIOXIDANT IN HUMAN-BLOOD PLASMA | 48 | 914 |
| 77 | 7 | 45 | 2043 1994 ANNALS OF NEUROLOGY 36(5):747-751 MECOCCI P; MACGARVEY U; BEAL MF OXIDATIVE DAMAGE TO MITOCHONDRIAL-DNA IS INCREASED IN ALZHEIMERS-DISEASE | 48 | 321 |
| 78 | 34 | 119 | 3473 1999 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 31(4):347-366 Barja G Mitochondrial oxygen radical generation and leak: Sites of production in state 4 and 3, organ specificity, and relation to aging and longevity | 48 | 88 |
| 79 | 3 | 25 | 361 1976 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 24(7):301-307 HARMAN D; HENDRICKS S; EDDY DE; SEIBOLD J FREE-RADICAL THEORY OF AGING - EFFECT OF DIETARY-FAT ON CENTRAL NERVOUS-SYSTEM FUNCTION | 47 | 47 |
| 80 | 59 | 279 | 2026 1994 AGE 17(4):119-146 HARMAN D AGING - PROSPECTS FOR FURTHER INCREASES IN THE FUNCTIONAL LIFE-SPAN | 47 | 47 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 9 | 25 | 2423 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(26):15671-15674 SOHAL RS; AGARWAL A; AGARWAL S; ORR WC SIMULTANEOUS OVEREXPRESSION OF COPPER-CONTAINING AND ZINC-CONTAINING SUPEROXIDE-DISMUTASE AND CATALASE RETARDS AGE-RELATED OXIDATIVE DAMAGE AND INCREASES METABOLIC POTENTIAL IN DROSOPHILA-MELANOGASTER | 47 | 109 |
| 82 | 4 | 42 | 557 1980 MECHANISMS OF AGEING AND DEVELOPMENT 14(1-2):101-118 HEGNER D AGE-DEPENDENCE OF MOLECULAR AND FUNCTIONAL-CHANGES IN BIOLOGICAL MEMBRANE-PROPERTIES | 46 | 151 |
| 83 | 7 | 33 | 1234 1989 MECHANISMS OF AGEING AND DEVELOPMENT 48(3):221-230 LAGANIERE S; YU BP EFFECT OF CHRONIC FOOD RESTRICTION IN AGING RATS .2. LIVER CYTOSOLIC ANTIOXIDANTS AND RELATED ENZYMES | 46 | 104 |
| 84 | 1 | 5 | 50 1960 JOURNALS OF GERONTOLOGY 15(1):38-40 HARMAN D THE FREE-RADICAL THEORY OF AGING - THE EFFECT OF AGE ON SERUM MERCAPTAN LEVELS | 45 | 45 |
| 85 | 24 | 172 | 896 1986 ADVANCES IN FREE RADICAL BIOLOGY AND MEDICINE 2(1):117-160 SOHAL RS; ALLEN RG RELATIONSHIP BETWEEN OXYGEN-METABOLISM, AGING AND DEVELOPMENT | 45 | 127 |
| 86 | 10 | 31 | 1169 1989 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 164(2):620-625 SEMSEI I; RAO G; RICHARDSON A CHANGES IN THE EXPRESSION OF SUPEROXIDE-DISMUTASE AND CATALASE AS A FUNCTION OF AGE AND DIETARY RESTRICTION | 45 | 104 |
| 87 | 2 | 14 | 1623 1992 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 189(2):979-985 HAYAKAWA M; HATTORI K; SUGIYAMA S; OZAWA T AGE-ASSOCIATED OXYGEN DAMAGE AND MUTATIONS IN MITOCHONDRIAL-DNA IN HUMAN HEARTS | 45 | 153 |
| 88 | 41 | 163 | 2630 1996 FREE RADICAL BIOLOGY AND MEDICINE 21(5):651-668 Yu BP Aging and oxidative stress: Modulation by dietary restriction | 45 | 130 |
| 89 | 3 | 24 | 105 1965 FEDERATION PROCEEDINGS 24(1P1):73-& TAPPEL AL FREE-RADICAL LIPID PEROXIDATION DAMAGE AND ITS INHIBITION BY VITAMIN E AND SELENIUM | 44 | 295 |
| 90 | 4 | 24 | 977 1987 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 145(3):1185-1191 LAGANIERE S; YU BP ANTI-LIPOPEROXIDATION ACTION OF FOOD RESTRICTION | 44 | 91 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 11 | 66 | 1385 1990 NEUROBIOLOGY OF AGING 11(5):567-571 VOLICER L; CRINO PB INVOLVEMENT OF FREE-RADICALS IN DEMENTIA OF THE ALZHEIMER TYPE - A HYPOTHESIS | 44 | 143 |
| 92 | 22 | 46 | 3671 2000 FASEB JOURNAL 14(2):312-318 Barja G; Herrero A Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals | 44 | 73 |
| 93 | 5 | 76 | 1357 1990 JOURNAL OF THE NEUROLOGICAL SCIENCES 100(1-2):14-21 MULLERHOCKER J CYTOCHROME-C-OXIDASE DEFICIENT FIBERS IN THE LIMB MUSCLE AND DIAPHRAGM OF MAN WITHOUT MUSCULAR DISEASE - AN AGE-RELATED ALTERATION | 43 | 143 |
| 94 | 8 | 41 | 1398 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(11):4270-4274 SETO NOL; HAYASHI S; TENER GM OVEREXPRESSION OF CU-ZN SUPEROXIDE-DISMUTASE IN DROSOPHILA DOES NOT AFFECT LIFE-SPAN | 43 | 77 |
| 95 | 5 | 30 | 1722 1992 JOURNAL OF THE NEUROLOGICAL SCIENCES 113(1):91-98 COOPER JM; MANN VM; SCHAPIRA AHV ANALYSES OF MITOCHONDRIAL RESPIRATORY-CHAIN FUNCTION AND MITOCHONDRIAL-DNA DELETION IN HUMAN SKELETAL-MUSCLE - EFFECT OF AGING | 43 | 155 |
| 96 | 12 | 51 | 3021 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(21):11168-11172 Yan LJ; Levine RL; Sohal RS Oxidative damage during aging targets mitochondrial aconitase | 43 | 162 |
| 97 | 11 | 49 | 804 1984 MECHANISMS OF AGEING AND DEVELOPMENT 27(3):341-358 HEIDRICK ML; HENDRICKS LC; COOK DE EFFECT OF DIETARY 2-MERCAPTOETHANOL ON THE LIFE-SPAN, IMMUNE-SYSTEM, TUMOR-INCIDENCE AND LIPID-PEROXIDATION DAMAGE IN SPLEEN LYMPHOCYTES OF AGING BC3F1 MICE | 42 | 55 |
| 98 | 3 | 29 | 1831 1993 BIOCHEMICAL JOURNAL 292:605-608 VANFLETEREN JR OXIDATIVE STRESS AND AGING IN CAENORHABDITIS-ELEGANS | 42 | 161 |
| 99 | 2 | 30 | 549 1980 LIFE SCIENCES 27(9):731-738 SAGAI M; ICHINOSE T AGE-RELATED-CHANGES IN LIPID-PEROXIDATION AS MEASURED BY ETHANE, ETHYLENE, BUTANE AND PENTANE IN RESPIRED GASES OF RATS | 41 | 124 |
| 100 | 2 | 41 | 945 1986 JOURNAL OF NUTRITION 116(4):641-654 WEINDRUCH R; WALFORD RL; FLIGIEL S; GUTHRIE D THE RETARDATION OF AGING IN MICE BY DIETARY RESTRICTION - LONGEVITY, CANCER, IMMUNITY AND LIFETIME ENERGY-INTAKE | 41 | 245 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 101 | 5 | 59 | 1272 1990 AMERICAN JOURNAL OF CLINICAL NUTRITION 52(3):557-563 MEYDANI SN; BARKLUND MP; LIU S; MEYDANI M; MILLER RA; et al. VITAMIN-E SUPPLEMENTATION ENHANCES CELL-MEDIATED-IMMUNITY IN HEALTHY ELDERLY SUBJECTS | 41 | 279 |
| 102 | 10 | 64 | 1776 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(19):9112-9116 YOUNGMAN LD; PARK JYK; AMES BN PROTEIN OXIDATION ASSOCIATED WITH AGING IS REDUCED BY DIETARY RESTRICTION OF PROTEIN OR CALORIES | 41 | 129 |
| 103 | 8 | 25 | 2123 1994 FREE RADICAL BIOLOGY AND MEDICINE 16(5):621-626 SOHAL RS; DUBEY A MITOCHONDRIAL OXIDATIVE DAMAGE, HYDROGEN-PEROXIDE RELEASE, AND AGING | 41 | 109 |
| 104 | 3 | 28 | 3581 1999 SCIENCE 286(5440):774-779 Michikawa Y; Mazzucchelli F; Bresolin N; Scarlato G; Attardi G Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication | 41 | 186 |
| 105 | 5 | 13 | 499 1979 JOURNALS OF GERONTOLOGY 34(4):497-501 CLAPP NK; SATTERFIELD LC; BOWLES ND EFFECTS OF THE ANTIOXIDANT BUTYLATED HYDROXYTOLUENE (BHT) ON MORTALITY IN BALB-C MICE | 39 | 45 |
| 106 | 3 | 21 | 1673 1992 FEBS LETTERS 297(1-2):34-38 ZHANG C; BAUMER A; MAXWELL RJ; LINNANE AW; NAGLEY P MULTIPLE MITOCHONDRIAL-DNA DELETIONS IN AN ELDERLY HUMAN INDIVIDUAL | 39 | 150 |
| 107 | 10 | 124 | 1789 1993 AGE 16(1):23-30 HARMAN D FREE-RADICAL THEORY OF AGING - A HYPOTHESIS ON PATHOGENESIS OF SENILE DEMENTIA OF THE ALZHEIMER TYPE | 39 | 39 |
| 108 | 11 | 33 | 1288 1990 BIOCHEMICAL JOURNAL 272(1):247-250 DEQUIROGA GB; PEREZCAMPO R; TORRES ML ANTIOXIDANT DEFENSES AND PEROXIDATION IN LIVER AND BRAIN OF AGED RATS | 38 | 66 |
| 109 | 9 | 32 | 2841 1997 BIOESSAYS 19(2):161-166 deGrey ADNJ A proposed refinement of the mitochondrial free radical theory of aging | 38 | 86 |
| 110 | 10 | 97 | 3811 2000 NATURE 408(6809):255-262 Guarente L; Kenyon C Genetic pathways that regulate ageing in model organisms | 38 | 282 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 111 | 8 | 35 | 2070 1994 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1226(1):37-43 LEE HC; PANG CY; HSU HS; WEI YH DIFFERENTIAL ACCUMULATIONS OF 4,977 BP DELETION IN MITOCHONDRIAL-DNA OF VARIOUS TISSUES IN HUMAN AGING | 37 | 114 |
| 112 | 11 | 35 | 2466 1995 MECHANISMS OF AGEING AND DEVELOPMENT 81(1):15-25 SOHAL RS; AGARWAL S; SOHAL BH OXIDATIVE STRESS AND AGING IN THE MONGOLIAN GERBIL (MERIONES-UNGUICULATUS) | 37 | 68 |
| 113 | 28 | 440 | 3012 1997 PHYSIOLOGICAL REVIEWS 77(2):425-464 Ozawa T Genetic and functional changes in mitochondria associated with aging | 37 | 122 |
| 114 | 4 | 66 | 847 1985 EXPERIMENTAL GERONTOLOGY 20(3-4):145-159 HAYFLICK L THEORIES OF BIOLOGICAL AGING | 36 | 100 |
| 115 | 15 | 69 | 3005 1997 NEW ENGLAND JOURNAL OF MEDICINE 337(14):986-994 Weindruch R; Sohal RS Caloric intake and aging | 36 | 160 |
| 116 | 5 | 31 | 367 1976 MECHANISMS OF AGEING AND DEVELOPMENT 5(5):347-370 MIQUEL J; LUNDGREN PR; BENSCH KG; ATLAN H EFFECTS OF TEMPERATURE ON LIFE-SPAN, VITALITY AND FINE-STRUCTURE OF DROSOPHILA-MELANOGASTER | 35 | 116 |
| 117 | 6 | 40 | 1545 1991 MOLECULAR AND CELLULAR BIOLOGY 11(2):632-640 REVEILLAUD I; NIEDZWIECKI A; BENSCH KG; FLEMING JE EXPRESSION OF BOVINE SUPEROXIDE-DISMUTASE IN DROSOPHILA-MELANOGASTER AUGMENTS RESISTANCE TO OXIDATIVE STRESS | 35 | 78 |
| 118 | 4 | 23 | 1615 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 297(1):35-41 ORR WC; SOHAL RS THE EFFECTS OF CATALASE GENE OVEREXPRESSION ON LIFE-SPAN AND RESISTANCE TO OXIDATIVE STRESS IN TRANSGENIC DROSOPHILA-MELANOGASTER | 35 | 71 |
| 119 | 21 | 277 | 2276 1995 AGE 18(3):97-119 Harman D Free radical theory of aging: Alzheimer's disease pathogenesis | 35 | 35 |
| 120 | 6 | 38 | 2976 1997 MECHANISMS OF AGEING AND DEVELOPMENT 98(2):95-111 Herrero A; Barja G Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon | 35 | 66 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 7 | 31 | 779 1984 EXPERIMENTAL GERONTOLOGY 19(1):31-36 MIQUEL J; FLEMING JE A 2-STEP HYPOTHESIS ON THE MECHANISMS OF INVITRO-CELL AGING - CELL-DIFFERENTIATION FOLLOWED BY INTRINSIC MITOCHONDRIAL MUTAGENESIS | 34 | 59 |
| 122 | 12 | 49 | 1355 1990 JOURNAL OF NUTRITION 120(6):602-609 RAO G; XIA EN; NADAKAVUKAREN MJ; RICHARDSON A EFFECT OF DIETARY RESTRICTION ON THE AGE-DEPENDENT CHANGES IN THE EXPRESSION OF ANTIOXIDANT ENZYMES IN RAT-LIVER | 34 | 103 |
| 123 | 4 | 29 | 1964 1993 MOLECULAR AND CELLULAR BIOCHEMISTRY 119(1-2):95-103 HAYAKAWA M; SUGIYAMA S; HATTORI K; TAKASAWA M; OZAWA T AGE-ASSOCIATED DAMAGE IN MITOCHONDRIAL-DNA IN HUMAN HEARTS | 34 | 79 |
| 124 | 8 | 30 | 2395 1995 FREE RADICAL BIOLOGY AND MEDICINE 19(4):499-504 SOHAL RS; SOHAL BH; ORR WC MITOCHONDRIAL SUPEROXIDE AND HYDROGEN-PEROXIDE GENERATION, PROTEIN OXIDATIVE DAMAGE, AND LONGEVITY IN DIFFERENT SPECIES OF FLIES | 34 | 77 |
| 125 | 12 | 121 | 3384 1999 CELL 96(2):291-302 Johnson FB; Sinclair DA; Guarente L Molecular biology of aging | 34 | 166 |
| 126 | 0 | 36 | 3492 1999 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 288(3):1143-1150 Ellis JL; Harman D; Gonzalez J; Spera ML; Liu RG; et al. Development of muscarinic analgesics derived from epibatidine: Role of the M-4 receptor subtype | 34 | 34 |
| 127 | 32 | 108 | 3970 2001 HEALTHY AGING FOR FUNCTIONAL LONGEVITY 928:1-21 Harman D Aging: Overview | 34 | 34 |
| 128 | 0 | 0 | 138 1968 GERONTOLOGIST 8(3P2):13-& HARMAN D FREE RADICAL THEORY OF AGING - EFFECT OF FREE RADICAL INHIBITORS ON LIFE SPAN OF MALE LAF1 MICE - SECOND EXPERIMENT | 33 | 33 |
| 129 | 6 | 28 | 1533 1991 MECHANISMS OF AGEING AND DEVELOPMENT 58(1):13-19 SEMSEI I; RAO G; RICHARDSON A EXPRESSION OF SUPEROXIDE-DISMUTASE AND CATALASE IN RAT-BRAIN AS A FUNCTION OF AGE | 33 | 53 |
| 130 | 8 | 35 | 3064 1998 ANNALS OF NEUROLOGY 43(2):217-223 Brierley EJ; Johnson MA; Lightowlers RN; James OFW; Turnbull DM Role of mitochondrial DNA mutations in human aging: Implications for the central nervous system and muscle | 33 | 105 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 131 | 2 | 36 | 952 1986 MECHANISMS OF AGEING AND DEVELOPMENT 34(2):191-201 MEYDANI SN; MEYDANI M; VERDON CP; SHAPIRO AA; BLUMBERG JB; et al. VITAMIN-E SUPPLEMENTATION SUPPRESSES PROSTAGLANDIN-E-2(1) SYNTHESIS AND ENHANCES THE IMMUNE-RESPONSE OF AGED MICE | 32 | 160 |
| 132 | 9 | 40 | 1814 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 301(1):34-40 ORR WC; SOHAL RS EFFECTS OF CU-ZN SUPEROXIDE-DISMUTASE OVEREXPRESSION ON LIFE-SPAN AND RESISTANCE TO OXIDATIVE STRESS IN TRANSGENIC DROSOPHILA-MELANOGASTER | 32 | 66 |
| 133 | 27 | 101 | 3127 1998 EXPERIMENTAL GERONTOLOGY 33(1-2):95-112 Harman D Extending functional life span | 32 | 32 |
| 134 | 2 | 36 | 360 1976 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 24(5):203-210 HARMAN D; EDDY DE; NOFFSINGER J FREE-RADICAL THEORY OF AGING - INHIBITION OF AMYLOIDOSIS IN MICE BY ANTIOXIDANTS - POSSIBLE MECHANISM | 31 | 31 |
| 135 | 12 | 79 | 2016 1993 VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY 422(1):7-15 MULLERHOCKER J; SEIBEL P; SCHNEIDERBANGER K; KADENBACH B DIFFERENT INSITU HYBRIDIZATION PATTERNS OF MITOCHONDRIAL-DNA IN CYTOCHROME-C OXIDASE-DEFICIENT EXTRAOCULAR-MUSCLE FIBERS IN THE ELDERLY | 31 | 78 |
| 136 | 6 | 53 | 2130 1994 FREE RADICAL BIOLOGY AND MEDICINE 17(5):411-418 CHEN JJ; YU BP ALTERATIONS IN MITOCHONDRIAL-MEMBRANE FLUIDITY BY LIPID-PEROXIDATION PRODUCTS | 31 | 111 |
| 137 | 34 | 133 | 2274 1995 AGE 18(2):51-62 Harman D Role of antioxidant nutrients in aging: Overview | 31 | 31 |
| 138 | 8 | 32 | 2620 1996 FASEB JOURNAL 10(2):333-338 DeLaAsuncion JG; Millan A; Pla R; Bruseghini L; Esteras A; et al. Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA | 31 | 87 |
| 139 | 5 | 25 | 3257 1998 NATURE 394(6694):694-697 Ishii N; Fujii M; Hartman PS; Tsuda M; Yasuda K; et al. A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes | 31 | 134 |
| 140 | 5 | 30 | 482 1979 EXPERIMENTAL GERONTOLOGY 14(5):279-285 MIQUEL J; ECONOMOS AC FAVORABLE EFFECTS OF THE ANTIOXIDANTS SODIUM AND MAGNESIUM THIAZOLIDINE CARBOXYLATE ON THE VITALITY AND LIFE-SPAN OF DROSOPHILA AND MICE | 30 | 44 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 141 | 3 | 203 | 616 1981 QUARTERLY REVIEW OF BIOLOGY 56(3):279-303 GENSLER HL; BERNSTEIN H DNA DAMAGE AS THE PRIMARY CAUSE OF AGING | 30 | 127 |
| 142 | 2 | 30 | 1382 1990 MUTATION RESEARCH 237(3-4):165-171 ISHII N; TAKAHASHI K; TOMITA S; KEINO T; HONDA S; et al. A METHYL VIOLOGEN-SENSITIVE MUTANT OF THE NEMATODE CAENORHABDITIS-ELEGANS | 30 | 62 |
| 143 | 2 | 58 | 1405 1990 SCIENCE 248(4952):189-194 STORZ G; TARTAGLIA LA; AMES BN TRANSCRIPTIONAL REGULATOR OF OXIDATIVE STRESS-INDUCIBLE GENES - DIRECT ACTIVATION BY OXIDATION | 30 | 567 |
| 144 | 28 | 76 | 3191 1998 JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY 168(3):149-158 Perez-Campo R; Lopez-Torres M; Cadenas S; Rojas C; Barja G The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach | 30 | 77 |
| 145 | 33 | 660 | 4346 2002 PHYSIOLOGICAL REVIEWS 82(1):47-95 Droge W Free radicals in the physiological control of cell function | 30 | 387 |
| 146 | 3 | 29 | 261 1973 FOOD AND COSMETICS TOXICOLOGY 11(2):199-207 ULLAND BM; WEISBURG.JH; YAMAMOTO RS; WEISBURG.EK ANTIOXIDANTS AND CARCINOGENESIS - BUTYLATED HYDROXYTOLUENE, BUT NOT DIPHENYL-PARA-PHENYLENEDIAMINE, INHIBITS CANCER INDUCTION BY N-2-FLUORENYL-ACETAMIDE AND BY N-HYDROXY-N-2-FLUORENYLACETAMIDE IN RATS | 29 | 161 |
| 147 | 5 | 33 | 818 1984 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81(18):5633-5637 CATHCART R; SCHWIERS E; SAUL RL; AMES BN THYMINE GLYCOL AND THYMIDINE GLYCOL IN HUMAN AND RAT URINE - A POSSIBLE ASSAY FOR OXIDATIVE DNA DAMAGE | 29 | 265 |
| 148 | 3 | 15 | 1450 1991 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 180(2):894-899 SUGIYAMA S; HATTORI K; HAYAKAWA M; OZAWA T QUANTITATIVE-ANALYSIS OF AGE-ASSOCIATED ACCUMULATION OF MITOCHONDRIAL-DNA WITH DELETION IN HUMAN HEARTS | 29 | 88 |
| 149 | 7 | 25 | 1537 1991 MECHANISMS OF AGEING AND DEVELOPMENT 60(2):189-198 SOHAL RS HYDROGEN-PEROXIDE PRODUCTION BY MITOCHONDRIA MAY BE A BIOMARKER OF AGING | 29 | 43 |
| 150 | 11 | 70 | 1747 1992 MUTATION RESEARCH 275(3-6):157-167 ARNHEIM N; CORTOPASSI G DELETERIOUS MITOCHONDRIAL-DNA MUTATIONS ACCUMULATE IN AGING HUMAN TISSUES | 29 | 94 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 151 | 12 | 38 | 2413 1995 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 27(7):647-653 RICHTER C OXIDATIVE DAMAGE TO MITOCHONDRIAL-DNA AND ITS RELATIONSHIP TO AGING | 29 | 117 |
| 152 | 11 | 59 | 2491 1995 NEUROLOGY 45(8):1594-1601 LOVELL MA; EHMANN WD; BUTLER SM; MARKESBERY WR ELEVATED THIOBARBITURIC ACID-REACTIVE SUBSTANCES AND ANTIOXIDANT ENZYME-ACTIVITY IN THE BRAIN IN ALZHEIMERS-DISEASE | 29 | 204 |
| 153 | 1 | 35 | 650 1982 GERONTOLOGY 28(2):108-113 VANELLA A; GEREMIA E; DURSO G; TIRIOLO P; DISILVESTRO I; et al. SUPEROXIDE-DISMUTASE ACTIVITIES IN AGING RAT-BRAIN | 28 | 50 |
| 154 | 3 | 42 | 723 1983 JOURNAL OF NUTRITION 113(5):944-950 CHIPALKATTI S; DE AK; AIYAR AS EFFECT OF DIET RESTRICTION ON SOME BIOCHEMICAL PARAMETERS RELATED TO AGING IN MICE | 28 | 60 |
| 155 | 12 | 104 | 1601 1992 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 663:85-96 AMES BN; SHIGENAGA MK OXIDANTS ARE A MAJOR CONTRIBUTOR TO AGING | 28 | 108 |
| 156 | 10 | 38 | 1878 1993 FREE RADICAL BIOLOGY AND MEDICINE 15(2):133-142 LOPEZTORRES M; PEREZCAMPO R; ROJAS C; CADENAS S; BARJA G SIMULTANEOUS INDUCTION OF SOD, GLUTATHIONE-REDUCTASE, GSH, AND ASCORBATE IN LIVER AND KIDNEY CORRELATES WITH SURVIVAL DURING AGING | 28 | 56 |
| 157 | 2 | 17 | 2308 1995 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 211(3):847-849 EDAMATSU R; MORI A; PACKER L THE SPIN-TRAP N-TERT-ALPHA-PHENYL-BUTYLNITRONE PROLONGS THE LIFE-SPAN OF THE SENESCENCE-ACCELERATED MOUSE | 28 | 67 |
| 158 | 2 | 22 | 65 1962 CIRCULATION RESEARCH 11(2):277-& HARMAN D ATHEROSCLEROSIS - INHIBITING EFFECT OF AN ANTIHISTAMINIC DRUG, CHLORPHENIRAMINE | 27 | 27 |
| 159 | 4 | 20 | 163 1969 SCIENCE 166(3912):1535-& CHIO KS; REISS U; FLETCHER B; TAPPEL AL PEROXIDATION OF SUBCELLULAR ORGANELLES - FORMATION OF LIPOFUSCINLIKE FLUORESCENT PIGMENTS | 27 | 194 |
| 160 | 3 | 30 | 307 1974 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 71(12):4763-4767 PACKER L; SMITH JR EXTENSION OF LIFESPAN OF CULTURED NORMAL HUMAN DIPLOID CELLS BY VITAMIN-E | 27 | 79 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 161 | 19 | 70 | 421 1978 AGE 1(4):143-152 HARMAN D FREE-RADICAL THEORY OF AGING - NUTRITIONAL IMPLICATIONS | 27 | 27 |
| 162 | 15 | 41 | 521 1980 AGE 3(4):100-102 HARMAN D FREE-RADICAL THEORY OF AGING - ORIGIN OF LIFE, EVOLUTION, AND AGING | 27 | 27 |
| 163 | 4 | 24 | 866 1985 JOURNAL OF THE NEUROLOGICAL SCIENCES 67(3):319-325 MARKLUND SL; ADOLFSSON R; GOTTFRIES CG; WINBLAD B SUPEROXIDE-DISMUTASE ISOENZYMES IN NORMAL BRAINS AND IN BRAINS FROM PATIENTS WITH DEMENTIA OF ALZHEIMER TYPE | 27 | 90 |
| 164 | 22 | 88 | 1752 1992 MUTATION RESEARCH 275(3-6):249-255 RICHTER C REACTIVE OXYGEN AND DNA DAMAGE IN MITOCHONDRIA | 27 | 123 |
| 165 | 9 | 51 | 1849 1993 BRITISH MEDICAL BULLETIN 49(3):653-667 NOHL H INVOLVEMENT OF FREE-RADICALS IN AGING - A CONSEQUENCE OR CAUSE OF SENESCENCE | 27 | 70 |
| 166 | 8 | 29 | 2544 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 333(1):189-197 Dubey A; Forster MJ; Lal H; Sohal RS Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of the mouse | 27 | 91 |
| 167 | 2 | 46 | 151 1969 BIOCHEMISTRY 8(7):2827-& CHIO KS; TAPPEL AL INACTIVATION OF RIBONUCLEASE AND OTHER ENZYMES BY PEROXIDIZING LIPIDS AND BY MALONALDEHYDE | 26 | 412 |
| 168 | 6 | 114 | 259 1973 FEDERATION PROCEEDINGS 32(8):1862-1869 PRYOR WA FREE-RADICAL REACTIONS AND THEIR IMPORTANCE IN BIOCHEMICAL SYSTEMS | 26 | 171 |
| 169 | 4 | 65 | 631 1982 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 396(OCT):83-94 SINET PM METABOLISM OF OXYGEN DERIVATIVES IN DOWNS-SYNDROME | 26 | 155 |
| 170 | 6 | 45 | 1038 1987 SCIENCE 235(4792):1043-1046 STOCKER R; YAMAMOTO Y; MCDONAGH AF; GLAZER AN; AMES BN BILIRUBIN IS AN ANTIOXIDANT OF POSSIBLE PHYSIOLOGICAL IMPORTANCE | 26 | 985 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 171 | 8 | 34 | 1068 1988 BIOCHIMICA ET BIOPHYSICA ACTA 966(3):269-275 RIKANS LE; MOORE DR EFFECT OF AGING ON AQUEOUS-PHASE ANTIOXIDANTS IN TISSUES OF MALE FISCHER RATS | 26 | 63 |
| 172 | 13 | 120 | 1546 1991 MUTATION RESEARCH 250(1-2):3-16 AMES BN; GOLD LS ENDOGENOUS MUTAGENS AND THE CAUSES OF AGING AND CANCER | 26 | 396 |
| 173 | 16 | 64 | 1746 1992 MUTATION RESEARCH 275(3-6):145-155 WEI YH MITOCHONDRIAL-DNA ALTERATIONS AS AGING-ASSOCIATED MOLECULAR EVENTS | 26 | 90 |
| 174 | 8 | 44 | 2388 1995 FREE RADICAL BIOLOGY AND MEDICINE 18(2):133-139 CHOI JH; YU BP BRAIN SYNAPTOSOMAL AGING - FREE-RADICALS AND MEMBRANE FLUIDITY | 26 | 83 |
| 175 | 10 | 45 | 3018 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(2):674-678 Butterfield DA; Howard BJ; Yatin S; Allen KL; Carney JM Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone | 26 | 112 |
| 176 | 21 | 267 | 3291 1998 PROGRESS IN NEUROBIOLOGY 56(3):359-384 Reiter RJ Oxidative damage in the central nervous system: Protection by melatonin | 26 | 300 |
| 177 | 1 | 5 | 44 1960 CIRCULATION 22(1):151-153 HARMAN D VITAMIN-E - EFFECT ON SERUM CHOLESTEROL AND LIPOPROTEINS | 25 | 25 |
| 178 | 1 | 12 | 331 1975 JOURNALS OF GERONTOLOGY 30(6):647-654 EDDY DE; HARMAN D RAT-BRAIN FATTY-ACID COMPOSITION - EFFECT OF DIETARY-FAT AND AGE | 25 | 25 |
| 179 | 3 | 20 | 395 1977 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 25(5):220-229 EDDY DE; HARMAN D FREE-RADICAL THEORY OF AGING - EFFECT OF AGE, SEX AND DIETARY PRECURSORS ON RAT-BRAIN DOCOSAHEXANOIC ACID | 25 | 25 |
| 180 | 5 | 99 | 456 1978 PHOTOCHEMISTRY AND PHOTOBIOLOGY 28(4-5):787-801 PRYOR WA FORMATION OF FREE-RADICALS AND CONSEQUENCES OF THEIR REACTIONS INVIVO | 25 | 178 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 181 | 4 | 36 | 785 1984 GERONTOLOGY 30(3):153-158 LAMMIKEEFE CJ; SWAN PB; HEGARTY PVJ COPPER-ZINC AND MANGANESE SUPEROXIDE-DISMUTASE ACTIVITIES IN CARDIAC AND SKELETAL-MUSCLES DURING AGING IN MALE-RATS | 25 | 36 |
| 182 | 3 | 16 | 1173 1989 BRAIN RESEARCH 476(1):160-162 ZEMLAN FP; THIENHAUS OJ; BOSMANN HB SUPEROXIDE-DISMUTASE ACTIVITY IN ALZHEIMERS-DISEASE - POSSIBLE MECHANISM FOR PAIRED HELICAL FILAMENT FORMATION | 25 | 97 |
| 183 | 7 | 31 | 1233 1989 MECHANISMS OF AGEING AND DEVELOPMENT 48(3):207-219 LAGANIERE S; YU BP EFFECT OF CHRONIC FOOD RESTRICTION IN AGING RATS .1. LIVER SUBCELLULAR MEMBRANES | 25 | 58 |
| 184 | 9 | 55 | 1430 1991 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 621:1-28 CUTLER RG HUMAN LONGEVITY AND AGING - POSSIBLE ROLE OF REACTIVE OXYGEN SPECIES | 25 | 69 |
| 185 | 2 | 51 | 1650 1992 CIRCULATION 86(3):803-811 SALONEN JT; NYYSSONEN K; KORPELA H; TUOMILEHTO J; SEPPANEN R; et al. HIGH STORED IRON LEVELS ARE ASSOCIATED WITH EXCESS RISK OF MYOCARDIAL-INFARCTION IN EASTERN FINNISH MEN | 25 | 569 |
| 186 | 5 | 108 | 2227 1994 NUTRITION REVIEWS 52(8):253-265 HALLIWELL B FREE-RADICALS AND ANTIOXIDANTS - A PERSONAL VIEW | 25 | 300 |
| 187 | 11 | 44 | 2746 1996 PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS 786:1-11 Yu BP; Yang R Critical evaluation of the free radical theory of aging - A proposal for the oxidative stress hypothesis | 25 | 42 |
| 188 | 4 | 28 | 3308 1998 TOWARDS PROLONGATION OF THE HEALTHY LIFE SPAN 854:1-7 Harman D Aging: Phenomena and theories | 25 | 25 |
| 189 | 13 | 61 | 3425 1999 FASEB JOURNAL 13(11):1385-1393 Honda Y; Honda S The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans | 25 | 115 |
| 190 | 11 | 54 | 392 1977 JOURNAL OF CELL BIOLOGY 74(1):58-67 BALIN AK; GOODMAN DBP; RASMUSSEN H; CRISTOFALO VJ EFFECT OF OXYGEN AND VITAMIN-E ON LIFESPAN OF HUMAN DIPLOID CELLS INVITRO | 24 | 57 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 191 | 9 | 41 | 463 1979 AGE 2(4):109-122 HARMAN D; EDDY DE FREE-RADICAL THEORY OF AGING - BENEFICIAL EFFECT OF ADDING ANTIOXIDANTS TO THE MATERNAL MOUSE DIET ON LIFE-SPAN OF OFFSPRING - POSSIBLE EXPLANATION OF THE SEX DIFFERENCE IN LONGEVITY | 24 | 24 |
| 192 | 2 | 13 | 538 1980 EXPERIMENTAL GERONTOLOGY 15(5):335-338 ENESCO HE; VERDONESMITH C ALPHA-TOCOPHEROL INCREASES LIFESPAN IN THE ROTIFER PHILODINA | 24 | 45 |
| 193 | 4 | 52 | 1748 1992 MUTATION RESEARCH 275(3-6):169-180 CORRALDEBRINSKI M; SHOFFNER JM; LOTT MT; WALLACE DC ASSOCIATION OF MITOCHONDRIAL-DNA DAMAGE WITH AGING AND CORONARY ATHEROSCLEROTIC HEART-DISEASE | 24 | 131 |
| 194 | 16 | 90 | 1756 1992 MUTATION RESEARCH 275(3-6):305-315 HOLMES GE; BERNSTEIN C; BERNSTEIN H OXIDATIVE AND OTHER DNA DAMAGES AS THE BASIS OF AGING - A REVIEW | 24 | 75 |
| 195 | 5 | 161 | 1865 1993 CRITICAL REVIEWS IN TOXICOLOGY 23(1):21-48 KEHRER JP FREE-RADICALS AS MEDIATORS OF TISSUE-INJURY AND DISEASE | 24 | 500 |
| 196 | 5 | 73 | 2373 1995 EXPERIMENTAL GERONTOLOGY 30(3-4):199-212 REITER RJ THE PINEAL-GLAND AND MELATONIN IN RELATION TO AGING - A SUMMARY OF THE THEORIES AND OF THE DATA | 24 | 106 |
| 197 | 6 | 25 | 2775 1996 SCIENCE 272(5264):1010-1013 Lakowski B; Hekimi S Determination of life-span in Caenorhabditis elegans by four clock genes | 24 | 153 |
| 198 | 27 | 79 | 4201 2002 FREE RADICAL BIOLOGY AND MEDICINE 33(5):575-586 Sohal RS; Mockett RJ; Orr WC Mechanisms of aging: An appraisal of the oxidative stress hypothesis | 24 | 58 |
| 199 | 4 | 48 | 721 1983 JOURNAL OF NEUROCHEMISTRY 40(4):1003-1007 DANH HC; BENEDETTI MS; DOSTERT P DIFFERENTIAL CHANGES IN SUPEROXIDE-DISMUTASE ACTIVITY IN BRAIN AND LIVER OF OLD RATS AND MICE | 23 | 68 |
| 200 | 2 | 5 | 897 1986 AGE 9(1):21-23 HARMAN D; MILLER RW EFFECT OF VITAMIN-E ON THE IMMUNE-RESPONSE TO INFLUENZA-VIRUS VACCINE AND THE INCIDENCE OF INFECTIOUS-DISEASE IN MAN | 23 | 23 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 201 | 3 | 194 | 912 1986 BIOLOGICAL REVIEWS OF THE CAMBRIDGE PHILOSOPHICAL SOCIETY 61(4):329-368 HOLEHAN AM; MERRY BJ THE EXPERIMENTAL MANIPULATION OF AGING BY DIET | 23 | 112 |
| 202 | 2 | 90 | 1599 1992 ANNALS OF NEUROLOGY 32(6):804-812 FAHN S; COHEN G THE OXIDANT STRESS HYPOTHESIS IN PARKINSONS-DISEASE - EVIDENCE SUPPORTING IT | 23 | 457 |
| 203 | 14 | 39 | 1600 1992 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 663:74-84 SOHAL RS; ORR WC RELATIONSHIP BETWEEN ANTIOXIDANTS, PROOXIDANTS, AND THE AGING PROCESS | 23 | 53 |
| 204 | 15 | 90 | 1637 1992 BRAIN PATHOLOGY 2(2):149-158 MULLERHOCKER J MITOCHONDRIA AND AGING | 23 | 65 |
| 205 | 9 | 37 | 1730 1992 MECHANISMS OF AGEING AND DEVELOPMENT 65(2-3):187-198 CARRILLO MC; KANAI S; SATO Y; KITANI K AGE-RELATED-CHANGES IN ANTIOXIDANT ENZYME-ACTIVITIES ARE REGION AND ORGAN, AS WELL AS SEX, SELECTIVE IN THE RAT | 23 | 58 |
| 206 | 13 | 47 | 1750 1992 MUTATION RESEARCH 275(3-6):209-216 MIQUEL J AN UPDATE ON THE MITOCHONDRIAL-DNA MUTATION HYPOTHESIS OF CELL AGING | 23 | 72 |
| 207 | 22 | 62 | 2118 1994 FREE RADICAL BIOLOGY AND MEDICINE 16(2):207-214 YEN TC; KING KL; LEE HC; YEH SH; WEI YH AGE-DEPENDENT INCREASE OF MITOCHONDRIAL-DNA DELETIONS TOGETHER WITH LIPID PEROXIDES AND SUPEROXIDE-DISMUTASE IN HUMAN LIVER-MITOCHONDRIA | 23 | 56 |
| 208 | 13 | 37 | 2706 1996 MECHANISMS OF AGEING AND DEVELOPMENT 86(1):53-66 Pamplona R; Prat J; Cadenas S; Rojas C; PerezCampo R; et al. Low fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from long-lived species: The pigeon and human case | 23 | 41 |
| 209 | 36 | 127 | 3288 1998 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 217(1):53-63 Wei YH Oxidative stress and mitochondrial DNA mutations in human aging | 23 | 101 |
| 210 | 0 | 9 | 184 1970 JOURNALS OF GERONTOLOGY 25(2):105-107 GIBAS MA; HARMAN D RIBONUCLEIC ACID SYNTHESIS BY NUCLEI ISOLATED FROM RATS OF DIFFERENT AGES | 22 | 22 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 211 | 6 | 30 | 987 1987 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 88(1):177-180 FAROOQUI MYH; DAY WW; ZAMORANO DM GLUTHATHIONE AND LIPID-PEROXIDATION IN THE AGING RAT | 22 | 57 |
| 212 | 3 | 38 | 1910 1993 JOURNAL OF INVESTIGATIVE DERMATOLOGY 100(3):260-265 SHINDO Y; WITT E; PACKER L ANTIOXIDANT DEFENSE-MECHANISMS IN MURINE EPIDERMIS AND DERMIS AND THEIR RESPONSES TO ULTRAVIOLET-LIGHT | 22 | 149 |
| 213 | 8 | 63 | 1950 1993 MECHANISMS OF AGEING AND DEVELOPMENT 70(3):177-199 LOPEZTORRES M; PEREZCAMPO R; ROJAS C; CADENAS S; BARJA G MAXIMUM LIFE-SPAN IN VERTEBRATES - RELATIONSHIP WITH LIVER ANTIOXIDANT ENZYMES, GLUTATHIONE SYSTEM, ASCORBATE, URATE, SENSITIVITY TO PEROXIDATION, TRUE MALONDIALDEHYDE, IN-VIVO H2O2, AND BASAL AND MAXIMUM AEROBIC CAPACITY | 22 | 34 |
| 214 | 12 | 61 | 2101 1994 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 108(4):501-512 BARJA G; CADENAS S; ROJAS C; LOPEZTORRES M; PEREZCAMPO R A DECREASE OF FREE-RADICAL PRODUCTION NEAR-CRITICAL TARGETS AS A CAUSE OF MAXIMUM LONGEVITY IN ANIMALS | 22 | 38 |
| 215 | 5 | 59 | 2322 1995 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1271(1):177-189 OZAWA T MECHANISM OF SOMATIC MITOCHONDRIAL-DNA MUTATIONS ASSOCIATED WITH AGE AND DISEASES | 22 | 75 |
| 216 | 10 | 48 | 3287 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(22):12896-12901 Yan LJ; Sohal RS Mitochondrial adenine nucleotide translocase is modified oxidatively during aging | 22 | 92 |
| 217 | 4 | 20 | 871 1985 MECHANISMS OF AGEING AND DEVELOPMENT 29(3):317-326 SOHAL RS; MULLER A; KOLETZKO B; SIES H EFFECT OF AGE AND AMBIENT-TEMPERATURE ON NORMAL-PENTANE PRODUCTION IN ADULT HOUSEFLY, MUSCA-DOMESTICA | 21 | 41 |
| 218 | 4 | 13 | 971 1987 AGE 10(2):58-61 HORRUM MA; HARMAN D; TOBIN RB FREE-RADICAL THEORY OF AGING - EFFECTS OF ANTIOXIDANTS ON MITOCHONDRIAL-FUNCTION | 21 | 21 |
| 219 | 4 | 48 | 1197 1989 GENETICS 122(3):643-652 MACKAY WJ; BEWLEY GC THE GENETICS OF CATALASE IN DROSOPHILA-MELANOGASTER - ISOLATION AND CHARACTERIZATION OF ACATALASEMIC MUTANTS | 21 | 50 |
| 220 | 3 | 11 | 1576 1991 SCIENCE 254(5038):1597-1597 FLOYD RA OXIDATIVE DAMAGE TO BEHAVIOR DURING AGING | 21 | 63 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 221 | 5 | 29 | 1961 1993 MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 25(2):225-231 JI LL ANTIOXIDANT ENZYME RESPONSE TO EXERCISE AND AGING | 21 | 138 |
| 222 | 4 | 60 | 1980 1993 NEUROENDOCRINOLOGY LETTERS 15(1-2):103-116 REITER RJ; POEGGELER B; TAN D; CHEN LD; MANCHESTER LC; et al. ANTIOXIDANT CAPACITY OF MELATONIN - A NOVEL ACTION NOT REQUIRING A RECEPTOR | 21 | 147 |
| 223 | 4 | 48 | 2027 1994 AGING CLOCK 719:1-12 REITER RJ; TAN DX; POEGGELER B; MENENDEZPELAEZ A; CHEN LD; et al. MELATONIN AS A FREE-RADICAL SCAVENGER - IMPLICATIONS FOR AGING AND AGE-RELATED DISEASES | 21 | 180 |
| 224 | 13 | 240 | 2570 1996 BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1276(2):87-105 Papa S Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications | 21 | 94 |
| 225 | 8 | 42 | 2721 1996 MUTATION RESEARCH-DNAGING GENETIC INSTABILITY AND AGING 316(5-6):277-285 Kaneko T; Tahara S; Matsuo M Non-linear accumulation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidized DNA damage, during aging | 21 | 77 |
| 226 | 8 | 73 | 2756 1996 PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS 786:362-378 Reiter RJ; Pablos MI; Agapito TT; Guerrero JM Melatonin in the context of the free radical theory of aging | 21 | 48 |
| 227 | 33 | 102 | 2838 1997 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1362(2-3):116-127 Rikans LE; Hornbrook KR Lipid peroxidation, antioxidant protection and aging | 21 | 68 |
| 228 | 9 | 31 | 3148 1998 FREE RADICAL BIOLOGY AND MEDICINE 24(9):1477-1484 Tian LQ; Cai QY; Wei HC Alterations of antioxidant enzymes and oxidative damage to macromolecules in different organs of rats during aging | 21 | 69 |
| 229 | 13 | 36 | 3153 1998 FREE RADICAL BIOLOGY AND MEDICINE 25(9):1089-1097 Lass A; Sohal BH; Weindruch R; Forster MJ; Sohal RS Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria | 21 | 68 |
| 230 | 1 | 67 | 34 1957 JOURNALS OF GERONTOLOGY 12(3):306-313 UPTON AC IONIZING-RADIATION AND THE AGING PROCESS - A REVIEW | 20 | 94 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 231 | 9 | 27 | 221 1972 AMERICAN JOURNAL OF CLINICAL NUTRITION 25(8):839-& HARMAN D FREE-RADICAL THEORY OF AGING - DIETARY IMPLICATIONS | 20 | 20 |
| 232 | 7 | 51 | 670 1982 NEUROBIOLOGY OF AGING 3(3):173-178 NODA Y; MCGEER PL; MCGEER EG LIPID PEROXIDES IN BRAIN DURING AGING AND VITAMIN-E-DEFICIENCY - POSSIBLE RELATIONS TO CHANGES IN NEUROTRANSMITTER INDEXES | 20 | 68 |
| 233 | 2 | 62 | 862 1985 JOURNAL OF NUTRITION 115(7):842-848 MASORO EJ NUTRITION AND AGING - A CURRENT ASSESSMENT | 20 | 133 |
| 234 | 4 | 19 | 1829 1993 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 196(1):7-11 SOHAL RS; KU HH; AGARWAL S BIOCHEMICAL CORRELATES OF LONGEVITY IN 2 CLOSELY-RELATED RODENT SPECIES | 20 | 40 |
| 235 | 8 | 38 | 1874 1993 EXPERIMENTAL GERONTOLOGY 28(3):269-280 TAKASAWA M; HAYAKAWA M; SUGIYAMA S; HATTORI K; ITO T; et al. AGE-ASSOCIATED DAMAGE IN MITOCHONDRIAL-FUNCTION IN RAT HEARTS | 20 | 51 |
| 236 | 10 | 156 | 2986 1997 MOLECULAR AND CELLULAR BIOCHEMISTRY 174(1-2):305-319 Papa S; Skulachev VP Reactive oxygen species, mitochondria, apoptosis and aging | 20 | 121 |
| 237 | 0 | 9 | 1 1942 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 64:2293-2294 Harman D; Stewart TD; Ruben S Tracer studies with radioactive hydrogen. The synthesis of labelled methyl iodide | 19 | 19 |
| 238 | 2 | 3 | 40 1959 COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES 153(7):1180-1182 BUUHOI NP; RATSIMAMANGA AR ACTION RETARDANTE DE LACIDE NORDIHYDROGUAIARETIQUE SUR LE VIEILLISSEMENT CHEZ LE RAT | 19 | 22 |
| 239 | 3 | 15 | 329 1975 JOURNAL OF INVESTIGATIVE DERMATOLOGY 65(4):412-414 BLACK HS; CHAN JT SUPPRESSION OF ULTRAVIOLET LIGHT-INDUCED TUMOR FORMATION BY DIETARY ANTIOXIDANTS | 19 | 81 |
| 240 | 7 | 70 | 461 1979 AGE 2(3):78-88 MIQUEL J; ECONOMOS AC; BENSCH KG; ATLAN H; JOHNSON JE REVIEW OF CELL AGING IN DROSOPHILA AND MOUSE | 19 | 32 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 241 | 4 | 32 | 875 1985 MECHANISMS OF AGEING AND DEVELOPMENT 32(1):77-83 JOZWIAK Z; JASNOWSKA B CHANGES IN OXYGEN-METABOLIZING ENZYMES AND LIPID-PEROXIDATION IN HUMAN-ERYTHROCYTES AS A FUNCTION OF AGE OF DONOR | 19 | 38 |
| 242 | 3 | 74 | 876 1985 MECHANISMS OF AGEING AND DEVELOPMENT 32(2-3):267-281 BEYER RE; BURNETT BA; CARTWRIGHT KJ; EDINGTON DW; FALZON MJ; et al. TISSUE COENZYME-Q (UBIQUINONE) AND PROTEIN CONCENTRATIONS OVER THE LIFE-SPAN OF THE LABORATORY RAT | 19 | 55 |
| 243 | 3 | 40 | 1064 1988 BIOCHEMICAL JOURNAL 256(1):205-212 HUNT JV; DEAN RT; WOLFF SP HYDROXYL RADICAL PRODUCTION AND AUTOXIDATIVE GLYCOSYLATION - GLUCOSE AUTOXIDATION AS THE CAUSE OF PROTEIN DAMAGE IN THE EXPERIMENTAL GLYCATION MODEL OF DIABETES-MELLITUS AND AGING | 19 | 433 |
| 244 | 7 | 449 | 1155 1989 AMERICAN REVIEW OF RESPIRATORY DISEASE 140(2):531-554 HEFFNER JE; REPINE JE PULMONARY STRATEGIES OF ANTIOXIDANT DEFENSE | 19 | 340 |
| 245 | 1 | 155 | 1226 1989 KIDNEY INTERNATIONAL 35(5):1093-1106 SHAH SV ROLE OF REACTIVE OXYGEN METABOLITES IN EXPERIMENTAL GLOMERULAR-DISEASE | 19 | 215 |
| 246 | 5 | 170 | 1297 1990 BLOOD 76(4):655-663 WEITZMAN SA; GORDON LI INFLAMMATION AND CANCER - ROLE OF PHAGOCYTE-GENERATED OXIDANTS IN CARCINOGENESIS | 19 | 299 |
| 247 | 4 | 17 | 1389 1990 NEUROSCIENCE LETTERS 112(2-3):333-337 HAJIMOHAMMADREZA I; BRAMMER M BRAIN MEMBRANE FLUIDITY AND LIPID-PEROXIDATION IN ALZHEIMERS-DISEASE | 19 | 73 |
| 248 | 3 | 33 | 1777 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(22):10721-10725 MORROW JD; AWAD JA; BOSS HJ; BLAIR IA; ROBERTS LJ NON-CYCLOOXYGENASE-DERIVED PROSTANOIDS (F2-ISOPROSTANES) ARE FORMED INSITU ON PHOSPHOLIPIDS | 19 | 277 |
| 249 | 4 | 43 | 2036 1994 AMERICAN JOURNAL OF PATHOLOGY 145(1):42-47 SMITH MA; KUTTY RK; RICHEY PL; YAN SD; STERN D; et al. HEME OXYGENASE-1 IS ASSOCIATED WITH THE NEUROFIBRILLARY PATHOLOGY OF ALZHEIMERS-DISEASE | 19 | 201 |
| 250 | 24 | 93 | 2127 1994 FREE RADICAL BIOLOGY AND MEDICINE 17(3):249-258 WARNER HR SUPEROXIDE-DISMUTASE, AGING, AND DEGENERATIVE DISEASE | 19 | 92 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 251 | 4 | 31 | 2149 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(6):4317-4326 MORROW JD; MINTON TA; MUKUNDAN CR; CAMPBELL MD; ZACKERT WE; et al. FREE RADICAL-INDUCED GENERATION OF ISOPROSTANES IN-VIVO - EVIDENCE FOR THE FORMATION OF D-RING AND E-RING ISOPROSTANES | 19 | 186 |
| 252 | 5 | 24 | 2189 1994 MECHANISMS OF AGEING AND DEVELOPMENT 75(1):11-19 AGARWAL S; SOHAL RS AGING AND PROTEIN OXIDATIVE DAMAGE | 19 | 29 |
| 253 | 6 | 35 | 2216 1994 NEUROCHEMICAL RESEARCH 19(9):1131-1137 BALAZS L; LEON M EVIDENCE OF AN OXIDATIVE CHALLENGE IN THE ALZHEIMERS BRAIN | 19 | 90 |
| 254 | 30 | 930 | 2234 1994 PHARMACOLOGY & THERAPEUTICS 63(1):37-122 GOTZ ME; KUNIG G; RIEDERER P; YOUDIM MBH OXIDATIVE STRESS - FREE-RADICAL PRODUCTION IN NEURAL DEGENERATION | 19 | 220 |
| 255 | 5 | 55 | 2375 1995 EXPERIMENTAL GERONTOLOGY 30(3-4):269-290 OZAWA T MITOCHONDRIAL-DNA MUTATIONS ASSOCIATED WITH AGING AND DEGENERATIVE DISEASES | 19 | 44 |
| 256 | 5 | 53 | 2442 1995 JOURNAL OF NEUROCHEMISTRY 64(3):1216-1223 GSELL W; CONRAD R; HICKETHIER M; SOFIC E; FROLICH L; et al. DECREASED CATALASE ACTIVITY BUT UNCHANGED SUPEROXIDE-DISMUTASE ACTIVITY IN BRAINS OF PATIENTS WITH DEMENTIA OF ALZHEIMER-TYPE | 19 | 77 |
| 257 | 14 | 45 | 2748 1996 PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS 786:24-43 Wei YH; Kao SH; Lee HC Simultaneous increase of mitochondrial DNA deletions and lipid peroxidation in human aging | 19 | 43 |
| 258 | 24 | 87 | 2755 1996 PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS 786:321-336 Harman D Aging and disease: Extending functional life span | 19 | 19 |
| 259 | 5 | 22 | 600 1981 MECHANISMS OF AGEING AND DEVELOPMENT 16(2):159-167 SOHAL RS; DONATO H; BIEHL ER EFFECT OF AGE AND METABOLIC-RATE ON LIPID-PEROXIDATION IN THE HOUSEFLY, MUSCA-DOMESTICA L | 18 | 48 |
| 260 | 20 | 72 | 658 1982 JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION 1(1):27-34 HARMAN D NUTRITIONAL IMPLICATIONS OF THE FREE-RADICAL THEORY OF AGING | 18 | 18 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 261 | 3 | 20 | 1035 1987 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 185(2):129-133 SCARPA M; RIGO A; VIGLINO P; STEVANATO R; BRACCO F; et al. AGE DEPENDENCE OF THE LEVEL OF THE ENZYMES INVOLVED IN THE PROTECTION AGAINST ACTIVE OXYGEN SPECIES IN THE RAT-BRAIN | 18 | 49 |
| 262 | 4 | 38 | 1387 1990 NEUROCHEMICAL RESEARCH 15(7):719-723 GEREMIA E; BARATTA D; ZAFARANA S; GIORDANO R; PINIZZOTTO MR; et al. ANTIOXIDANT ENZYMATIC SYSTEMS IN NEURONAL AND GLIAL CELL-ENRICHED FRACTIONS OF RAT-BRAIN DURING AGING | 18 | 60 |
| 263 | 3 | 27 | 1431 1991 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 621:337-352 MASORO EJ; SHIMOKAWA I; YU BP RETARDATION OF THE AGING PROCESSES IN RATS BY FOOD RESTRICTION | 18 | 88 |
| 264 | 6 | 41 | 1629 1992 BIOCHEMISTRY INTERNATIONAL 26(3):457-468 YEN TC; PANG CY; HSIEH RH; SU CH; KING KL; et al. AGE-DEPENDENT 6KB DELETION IN HUMAN LIVER MITOCHONDRIAL-DNA | 18 | 35 |
| 265 | 9 | 44 | 1706 1992 JOURNAL OF CELLULAR BIOCHEMISTRY 48(3):296-304 SAWADA M; SESTER U; CARLSON JC SUPEROXIDE RADICAL FORMATION AND ASSOCIATED BIOCHEMICAL-ALTERATIONS IN THE PLASMA-MEMBRANE OF BRAIN, HEART, AND LIVER DURING THE LIFETIME OF THE RAT | 18 | 39 |
| 266 | 4 | 49 | 1711 1992 JOURNAL OF LIPID RESEARCH 33(7):1051-1058 MIYAZAWA T; SUZUKI T; FUJIMOTO K; YASUDA K CHEMILUMINESCENT SIMULTANEOUS DETERMINATION OF PHOSPHATIDYLCHOLINE HYDROPEROXIDE AND PHOSPHATIDYLETHANOLAMINE HYDROPEROXIDE IN THE LIVER AND BRAIN OF THE RAT | 18 | 90 |
| 267 | 18 | 51 | 1728 1992 MECHANISMS OF AGEING AND DEVELOPMENT 64(3):273-292 MATSUO M; GOMI F; DOOLEY MM AGE-RELATED ALTERATIONS IN ANTIOXIDANT CAPACITY AND LIPID-PEROXIDATION IN BRAIN, LIVER, AND LUNG HOMOGENATES OF NORMAL AND VITAMIN-E-DEFICIENT RATS | 18 | 44 |
| 268 | 9 | 51 | 1749 1992 MUTATION RESEARCH 275(3-6):195-208 LINNANE AW; ZHANG CF; BAUMER A; NAGLEY P MITOCHONDRIAL-DNA MUTATION AND THE AGING PROCESS - BIOENERGY AND PHARMACOLOGICAL INTERVENTION | 18 | 96 |
| 269 | 18 | 44 | 1942 1993 LIPIDS 28(9):789-793 MIYAZAWA T; SUZUKI T; FUJIMOTO K AGE-DEPENDENT ACCUMULATION OF PHOSPHATIDYLCHOLINE HYDROPEROXIDE IN THE BRAIN AND LIVER OF THE RAT | 18 | 38 |
| 270 | 4 | 26 | 2335 1995 BRAIN RESEARCH 693(1-2):88-94 SOCCI DJ; CRANDALL BM; ARENDASH GW CHRONIC ANTIOXIDANT TREATMENT IMPROVES THE COGNITIVE PERFORMANCE OF AGED RATS | 18 | 58 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 271 | 7 | 31 | 2556 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 226(2):369-377 Hayakawa M; Katsumata K; Yoneda M; Tanaka M; Sugiyama S; et al. Age-related extensive fragmentation of mitochondrial DNA into minicircles | 18 | 36 |
| 272 | 6 | 43 | 2638 1996 HEPATOLOGY 24(5):1199-1205 Sastre J; Pallardo FV; Pla R; Pellin A; Juan G; et al. Aging of the liver: Age-associated mitochondrial damage in intact hepatocytes | 18 | 57 |
| 273 | 7 | 40 | 3143 1998 FREE RADICAL BIOLOGY AND MEDICINE 24(2):298-304 Sastre J; Millan A; delaAsuncion JG; Pla R; Juan G; et al. A Ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress | 18 | 57 |
| 274 | 6 | 33 | 3181 1998 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 30(3):235-243 Barja G; Herrero A Localization at complex I and mechanism of the higher free radical production of brain nonsynaptic mitochondria in the short-lived rat than in the longevous pigeon | 18 | 37 |
| 275 | 6 | 36 | 3219 1998 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 46(7):833-838 Paolisso G; Tagliamonte MR; Rosaria M; Manzella D; Gambardella A; et al. Oxidative stress and advancing age: Results in healthy centenarians | 18 | 45 |
| 276 | 6 | 53 | 3241 1998 MECHANISMS OF AGEING AND DEVELOPMENT 103(3):269-284 Lipman RD; Bronson RT; Wu D; Smith DE; Prior R; et al. Disease incidence and longevity are unaltered by dietary antioxidant supplementation initiated during middle age in C57BL/6 mice | 18 | 40 |
| 277 | 5 | 30 | 3286 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(16):9562-9566 Hagen TM; Ingersoll RT; Wehr CM; Lykkesfeldt J; Vinarsky V; et al. Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity | 18 | 69 |
| 278 | 24 | 71 | 3315 1998 TOWARDS PROLONGATION OF THE HEALTHY LIFE SPAN 854:224-238 Barja G Mitochondrial free radical production and aging in mammals and birds | 18 | 45 |
| 279 | 14 | 41 | 3435 1999 FREE RADICAL BIOLOGY AND MEDICINE 26(3-4):303-308 Mecocci P; Fano G; Fulle S; MacGarvey U; Shinobu L; et al. Age-dependent increases in oxidative damage to DNA, lipids, and proteins in human skeletal muscle | 18 | 74 |
| 280 | 3 | 14 | 58 1961 LANCET 1(717):200-& HARMAN D MUTATION, CANCER, AND AGEING | 17 | 17 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 281 | 0 | 0 | 81 1963 CIRCULATION 28(4):658-& HARMAN D ROLE OF SERUM COPPER IN CORONARY ATHEROSCLEROSIS | 17 | 17 |
| 282 | 3 | 94 | 233 1972 EXPERIMENTAL GERONTOLOGY 7(4):227-& MEDVEDEV ZA REPETITION OF MOLECULAR-GENETIC INFORMATION AS A POSSIBLE FACTOR IN EVOLUTIONARY CHANGES OF LIFE-SPAN | 17 | 63 |
| 283 | 11 | 54 | 366 1976 MECHANISMS OF AGEING AND DEVELOPMENT 5(2):79-98 MUNKRES KD; MINSSEN M AGING OF NEUROSPORA-CRASSA .1. EVIDENCE FOR FREE-RADICAL THEORY OF AGING FROM STUDIES OF A NATURAL-DEATH MUTANT | 17 | 44 |
| 284 | 5 | 55 | 444 1978 JOURNALS OF GERONTOLOGY 33(1):5-19 MIQUEL J; LUNDGREN PR; JOHNSON JE SPECTRO-PHOTO-FLUOROMETRIC AND ELECTRON-MICROSCOPIC STUDY OF LIPOFUSCIN ACCUMULATION IN TESTIS OF AGING MICE | 17 | 49 |
| 285 | 3 | 16 | 552 1980 MECHANISMS OF AGEING AND DEVELOPMENT 12(3):279-286 MASSIE HR; AIELLO VR; WILLIAMS TR CHANGES IN SUPEROXIDE-DISMUTASE ACTIVITY AND COPPER DURING DEVELOPMENT AND AGING IN THE FRUIT-FLY DROSOPHILA-MELANOGASTER | 17 | 37 |
| 286 | 14 | 611 | 698 1983 BIOLOGICAL REVIEWS OF THE CAMBRIDGE PHILOSOPHICAL SOCIETY 58(3):343-422 MAKRIDES SC PROTEIN-SYNTHESIS AND DEGRADATION DURING AGING AND SENESCENCE | 17 | 101 |
| 287 | 2 | 33 | 1174 1989 BRITISH JOURNAL OF NUTRITION 62(1):221-227 CAMPBELL D; BUNKER VW; THOMAS AJ; CLAYTON BE SELENIUM AND VITAMIN-E STATUS OF HEALTHY AND INSTITUTIONALIZED ELDERLY SUBJECTS - ANALYSIS OF PLASMA, ERYTHROCYTES AND PLATELETS | 17 | 54 |
| 288 | 3 | 37 | 1471 1991 CLINICAL CHEMISTRY 37(11):1932-1937 GUEMOURI L; ARTUR Y; HERBETH B; JEANDEL C; CUNY G; et al. BIOLOGICAL VARIABILITY OF SUPEROXIDE-DISMUTASE, GLUTATHIONE-PEROXIDASE, AND CATALASE IN BLOOD | 17 | 125 |
| 289 | 7 | 38 | 1655 1992 CLINICAL CHEMISTRY 38(1):66-70 CEBALLOSPICOT I; TRIVIER JM; NICOLE A; SINET PM; THEVENIN M AGE-CORRELATED MODIFICATIONS OF COPPER-ZINC SUPEROXIDE-DISMUTASE AND GLUTATHIONE-RELATED ENZYME-ACTIVITIES IN HUMAN ERYTHROCYTES | 17 | 63 |
| 290 | 12 | 60 | 1971 1993 MUTATION RESEARCH 295(4-6):191-200 FEUERS RJ; WEINDRUCH R; HART RW CALORIC RESTRICTION, AGING, AND ANTIOXIDANT ENZYMES | 17 | 39 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 291 | 6 | 75 | 2374 1995 EXPERIMENTAL GERONTOLOGY 30(3-4):213-227 PIERREFICHE G; LABORIT H OXYGEN-FREE RADICALS, MELATONIN, AND AGING | 17 | 75 |
| 292 | 8 | 43 | 2541 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 331(2):232-240 Conconi M; Szweda LI; Levine RL; Stadtman ER; Friguet B Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90 | 17 | 87 |
| 293 | 2 | 42 | 2654 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(8):4138-4142 Guyton KZ; Liu YS; Gorospe M; Xu QB; Holbrook NJ Activation of mitogen-activated protein kinase by H2O2 - Role in cell survival following oxidant injury | 17 | 584 |
| 294 | 23 | 65 | 3231 1998 MECHANISMS OF AGEING AND DEVELOPMENT 100(2):157-168 Aksenova MV; Aksenov MY; Carney JM; Butterfield DA Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction | 17 | 40 |
| 295 | 11 | 62 | 3514 1999 MECHANISMS OF AGEING AND DEVELOPMENT 110(3):157-173 Reiter RJ; Tan DX; Kim SJ; Manchester LC; Qi WB; et al. Augmentation of indices of oxidative damage in life-long melatonin-deficient rats | 17 | 54 |
| 296 | 7 | 64 | 3955 2001 FASEB JOURNAL 15(2):322-332 Wanagat J; Cao ZJ; Pathare P; Aiken JM Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia | 17 | 42 |
| 297 | 5 | 143 | 68 1962 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 10(2):125-& BJORKSTEN J AGING - PRESENT STATUS OF OUR CHEMICAL KNOWLEDGE | 16 | 56 |
| 298 | 3 | 24 | 165 1970 AMERICAN JOURNAL OF CLINICAL NUTRITION 23(8):1137-& TAPPEL AL BIOLOGICAL ANTIOXIDANT PROTECTION AGAINST LIPID PEROXIDATION DAMAGE | 16 | 72 |
| 299 | 6 | 95 | 553 1980 MECHANISMS OF AGEING AND DEVELOPMENT 13(1):1-39 PORTA EA; JOUN NS; NITTA RT EFFECTS OF THE TYPE OF DIETARY-FAT AT 2 LEVELS OF VITAMIN-E IN WISTAR MALE-RATS DURING DEVELOPMENT AND AGING .1. LIFE-SPAN, SERUM BIOCHEMICAL PARAMETERS AND PATHOLOGICAL-CHANGES | 16 | 32 |
| 300 | 6 | 43 | 633 1982 BIOCHEMICAL PHARMACOLOGY 31(11):2113-2116 STOHS SJ; ALTURK WA; ANGLE CR GLUTATHIONE S-TRANSFERASE AND GLUTATHIONE-REDUCTASE ACTIVITIES IN HEPATIC AND EXTRA-HEPATIC TISSUES OF FEMALE MICE AS A FUNCTION OF AGE | 16 | 45 |
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