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Nodes: 4913,
Authors: 11522,
Journals: 1289,
Outer References: 158983,
Words: 7709
Collection span: 1942 - 2005
View: Overview. Sorted by LCR.
Page 2: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
---|---|---|---|---|---|
301 | 14 | 102 | 4510 2003 GENES & DEVELOPMENT 17(3):313-321 Koubova J; Guarente L How does calorie restriction work? | 1 | 34 |
302 | 14 | 143 | 4610 2003 NUCLEIC ACIDS RESEARCH 31(2):517-531 Kamiya H Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides | 5 | 22 |
303 | 14 | 41 | 4655 2004 AGING CELL 3(1):7-12 Merry BJ Oxidative stress and mitochondrial function with aging - the effects of calorie restriction | 2 | 5 |
304 | 14 | 76 | 4858 2004 NATURE REVIEWS MOLECULAR CELL BIOLOGY 5(1):69-75 Lieber MR; Karanjawala ZE Ageing, repetitive genomes and DNA damage | 1 | 2 |
305 | 13 | 216 | 209 1971 JOURNAL OF PHARMACEUTICAL SCIENCES 60(2):167-& KORMENDY CG; BENDER AD EXPERIMENTAL MODIFICATION OF CHEMISTRY AND BIOLOGY OF AGING PROCESS | 0 | 6 |
306 | 13 | 130 | 1076 1988 COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES 182(1):5-36 BOURRE JM FREE-RADICALS, POLYUNSATURATED FATTY-ACIDS, CELLULAR DEATH, BRAINS AGING | 0 | 7 |
307 | 13 | 23 | 1115 1988 MOLECULAR AND CELLULAR BIOCHEMISTRY 84(2):155-161 HARMAN D FREE-RADICALS IN AGING | 79 | 79 |
308 | 13 | 120 | 1546 1991 MUTATION RESEARCH 250(1-2):3-16 AMES BN; GOLD LS ENDOGENOUS MUTAGENS AND THE CAUSES OF AGING AND CANCER | 26 | 396 |
309 | 13 | 128 | 1737 1992 MEDICAL LABORATORY SCIENCES 49(4):299-312 BUNKER VW FREE-RADICALS, ANTIOXIDANTS AND AGING | 16 | 36 |
310 | 13 | 47 | 1750 1992 MUTATION RESEARCH 275(3-6):209-216 MIQUEL J AN UPDATE ON THE MITOCHONDRIAL-DNA MUTATION HYPOTHESIS OF CELL AGING | 23 | 72 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
311 | 13 | 36 | 1941 1993 LIPIDS 28(8):775-778 SUZUKI T; MIYAZAWA T; FUJIMOTO K; OTSUKA M; TSUTSUMI M AGE-RELATED ACCUMULATION OF PHOSPHATIDYLCHOLINE HYDROPEROXIDE IN CULTURED HUMAN-DIPLOID CELLS AND ITS PREVENTION BY ALPHA-TOCOPHEROL | 8 | 20 |
312 | 13 | 69 | 1956 1993 MEDICAL HYPOTHESES 41(5):473-482 GREENSTOCK CL RADIATION AND AGING - FREE-RADICAL DAMAGE, BIOLOGICAL RESPONSE AND POSSIBLE ANTIOXIDANT INTERVENTION | 2 | 16 |
313 | 13 | 36 | 1978 1993 NEUROCHEMISTRY INTERNATIONAL 23(2):157-162 LUPO G; ANFUSO CD; ALBERGHINA M AGING DOES NOT AFFECT THE SUSCEPTIBILITY TO LIPID-PEROXIDATION AND LYSOSOMAL-ENZYME RELEASE OF RAT VISUAL-SYSTEM STRUCTURES AND SCIATIC-NERVE | 0 | 3 |
314 | 13 | 270 | 2386 1995 FOOD AND CHEMICAL TOXICOLOGY 33:S1-S100 ROE FJC; LEE PN; CONYBEARE G; KELLY D; MATTER B; et al. THE BIOSURE STUDY - INFLUENCE OF COMPOSITION OF DIET AND FOOD-CONSUMPTION ON LONGEVITY, DEGENERATIVE DISEASES AND NEOPLASIA IN WISTAR RATS STUDIED FOR UP TO 30 MONTHS POST-WEANING | 0 | 28 |
315 | 13 | 42 | 2415 1995 INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 13(8):811-817 Hussain S; Slikker W; Ali SF Age-related changes in antioxidant enzymes, superoxide dismutase, catalase, glutathione peroxidase and glutathione in different regions of mouse brain | 11 | 45 |
316 | 13 | 48 | 2457 1995 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 50(3):B117-B127 DUDAS SP; ARKING R A COORDINATE UP-REGULATION OF ANTIOXIDANT GENE ACTIVITIES IS ASSOCIATED WITH THE DELAYED-ONSET OF SENESCENCE IN A LONG-LIVED STRAIN OF DROSOPHILA | 0 | 60 |
317 | 13 | 43 | 2468 1995 MECHANISMS OF AGEING AND DEVELOPMENT 83(1):55-64 ASANUMA A; YAMAUCHI Y; KOGA T; KATAYAMA I SUPPRESSION OF AGE-RELATED-CHANGES IN MOUSE HIPPOCAMPAL CA3 NERVE-CELLS BY A FREE-RADICAL SCAVENGER | 0 | 2 |
318 | 13 | 32 | 2486 1995 NEUROBIOLOGY OF AGING 16(1):53-57 CINI M; MORETTI A STUDIES ON LIPID-PEROXIDATION AND PROTEIN OXIDATION IN THE AGING BRAIN | 9 | 32 |
319 | 13 | 39 | 2567 1996 BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL 40(4):731-740 Bains JS; Kakkar R; Sharma SP Gender specific alterations in antioxidant status of aging Zaprionus paravittiger fed on propyl gallate | 3 | 6 |
320 | 13 | 240 | 2570 1996 BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1276(2):87-105 Papa S Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications | 21 | 94 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
321 | 13 | 47 | 2636 1996 GERONTOLOGY 42(6):312-321 Kakkar R; Bains JS; Sharma SP Effect of vitamin E on life span, malondialdehyde content and antioxidant enzymes in aging Zaprionus paravittiger | 3 | 5 |
322 | 13 | 37 | 2706 1996 MECHANISMS OF AGEING AND DEVELOPMENT 86(1):53-66 Pamplona R; Prat J; Cadenas S; Rojas C; PerezCampo R; et al. Low fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from long-lived species: The pigeon and human case | 23 | 41 |
323 | 13 | 51 | 2720 1996 MUTATION RESEARCH-DNAGING GENETIC INSTABILITY AND AGING 316(5-6):209-236 Kowald A; Kirkwood TBL A network theory of ageing: The interactions of defective mitochondria, aberrant proteins, free radicals and scavengers in the ageing process | 13 | 47 |
324 | 13 | 48 | 2979 1997 MECHANISMS OF AGEING AND DEVELOPMENT 99(3):181-192 Gong X; Shang F; Obin M; Palmer H; Scrofano MM; et al. Antioxidant enzyme activities in lens, liver and kidney of calorie restricted Emory mice | 1 | 8 |
325 | 13 | 71 | 2981 1997 MEDICAL HYPOTHESES 48(2):143-148 Ying W Deleterious network hypothesis of aging | 4 | 11 |
326 | 13 | 44 | 3049 1998 AGE 21(3):109-117 Chandwaney R; Leichtweis S; Leeuwenburgh C; Ji LL Oxidative stress and mitochondrial function in skeletal muscle: Effects of aging and exercise training | 3 | 9 |
327 | 13 | 47 | 3083 1998 BIOLOGICAL & PHARMACEUTICAL BULLETIN 21(12):1271-1276 Sato A; Huang MZ; Watanabe S; Okuyama H; Nakamoto H; et al. Protein carbonyl content roughly reflects the unsaturation of lipids in muscle but not in other tissues of stroke-prone spontaneously hypertensive strain (SHRSP) rats fed different fats and oils | 3 | 6 |
328 | 13 | 36 | 3153 1998 FREE RADICAL BIOLOGY AND MEDICINE 25(9):1089-1097 Lass A; Sohal BH; Weindruch R; Forster MJ; Sohal RS Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria | 21 | 68 |
329 | 13 | 336 | 3299 1998 REVIEWS IN THE NEUROSCIENCES 9(3):169-201 Lynch MA Analysis of the mechanisms underlying the age-related impairment in long-term potentiation in the rat | 2 | 14 |
330 | 13 | 53 | 3316 1998 TOWARDS PROLONGATION OF THE HEALTHY LIFE SPAN 854:239-250 Mori A; Utsumi K; Liu JK; Hosokawa M Oxidative damage in the senescence-accelerated mouse | 4 | 12 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
331 | 13 | 61 | 3323 1998 TOWARDS PROLONGATION OF THE HEALTHY LIFE SPAN 854:448-462 Butterfield DA; Koppal T; Howard B; Subramaniam R; Hall N; et al. Structural and functional changes in proteins induced by free radical-mediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin E | 4 | 23 |
332 | 13 | 117 | 3396 1999 CURRENT SCIENCE 77(5):658-666 Bandyopadhyay U; Das D; Banerjee RK Reactive oxygen species: Oxidative damage and pathogenesis | 1 | 22 |
333 | 13 | 44 | 3417 1999 EXPERIMENTAL GERONTOLOGY 34(3):365-374 Nayak SB; Jena BS; Patnaik BK Effects of age and manganese (II) chloride on peroxidase activity of brain and liver of the teleost, Channa punctatus | 0 | 1 |
334 | 13 | 61 | 3425 1999 FASEB JOURNAL 13(11):1385-1393 Honda Y; Honda S The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans | 25 | 115 |
335 | 13 | 42 | 3531 1999 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 423(1-2):11-21 Lu CY; Lee HC; Fahn HJ; Wei YH Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin | 6 | 35 |
336 | 13 | 87 | 3545 1999 NEUROPROTECTIVE AGENTS: FOURTH INTERNATIONAL CONFERENCE 890:471-485 Reiter RJ; Cabrera J; Sainz RM; Mayo JC; Manchester LC; et al. Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and Parkinsonism | 2 | 32 |
337 | 13 | 49 | 3584 1999 TOXICOLOGICAL SCIENCES 52(2):35-40 Wanagat J; Allison DB; Weindruch R Caloric intake and aging: Mechanisms in rodents and a study in nonhuman primates | 2 | 32 |
338 | 13 | 86 | 3627 2000 BIOLOGICAL SIGNALS AND RECEPTORS 9(3-4):160-171 Reiter RJ; Tan DX; Qi WB; Manchester LC; Karbownik M; et al. Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo | 1 | 69 |
339 | 13 | 64 | 3649 2000 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 125(2):147-160 Zielinski S; Portner HO Oxidative stress and antioxidative defense in cephalopods: a function of metabolic rate or age? | 1 | 9 |
340 | 13 | 57 | 3682 2000 FREE RADICAL BIOLOGY AND MEDICINE 28(5):701-708 Sitte N; Merker K; von Zglinicki T; Grune T Protein oxidation and degradation during proliferative senescence of human MRC-5 fibroblasts | 6 | 41 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
341 | 13 | 184 | 3691 2000 FREE RADICAL BIOLOGY AND MEDICINE 29(10):946-968 Ramsey JJ; Harper ME; Weindruch R Restriction of energy intake, energy expenditure, and aging | 14 | 39 |
342 | 13 | 58 | 3715 2000 JOURNAL OF ANATOMY 197:521-528 Gems D An integrated theory of ageing in the nematode Caenorhabditis elegans | 0 | 4 |
343 | 13 | 81 | 3735 2000 JOURNAL OF EXPERIMENTAL BIOLOGY 203(10):1513-1521 Morre DM; Lenaz G; Morre DJ Surface oxidase and oxidative stress propagation in aging | 7 | 25 |
344 | 13 | 57 | 3743 2000 JOURNAL OF NUTRITIONAL BIOCHEMISTRY 11(3):122-127 Arivazhagan P; Thilakavathy T; Panneerselvam C Antioxidant lipoate and tissue antioxidants in aged rats | 2 | 11 |
345 | 13 | 124 | 3796 2000 MOLECULAR AND CELLULAR GERONTOLOGY 908:111-125 Chen QM Replicative senescence and oxidant-induced premature senescence - Beyond the control of cell cycle checkpoints | 3 | 26 |
346 | 13 | 93 | 3797 2000 MOLECULAR AND CELLULAR GERONTOLOGY 908:143-154 Friguet B; Bulteau AL; Chondrogianni N; Conconi M; Petropoulos I Protein degradation by the proteasome and its implications in aging | 4 | 45 |
347 | 13 | 190 | 3917 2001 CNS DRUGS 15(4):287-310 Yao JK; Reddy RD; van Kammen DP Oxidative damage and schizophrenia - An overview of the evidence and its therapeutic implications | 1 | 30 |
348 | 13 | 136 | 3971 2001 HEALTHY AGING FOR FUNCTIONAL LONGEVITY 928:22-38 Stadtman ER Protein oxidation in aging and age-related diseases | 11 | 63 |
349 | 13 | 37 | 3992 2001 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 33(4):279-287 Gredilla R; Barja G; Lopez-Torres M Effect of short-term caloric restriction on H2O2 production and oxidative DNA damage in rat liver mitochondria and location of the free radical source | 13 | 29 |
350 | 13 | 34 | 4005 2001 JOURNAL OF NEURAL TRANSMISSION 108(8-9):955-967 Leutner S; Eckert A; Muller WE ROS generation, lipid peroxidation and antioxidant enzyme activities in the aging brain | 2 | 13 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
351 | 13 | 50 | 4016 2001 JOURNAL OF THE AMERICAN AGING ASSOCIATION 24(4):179-186 Honda Y; Honda S Life span extensions associated with upregulation of gene expression of antioxidant enzymes in Caenorhabditis elegans; Studies of mutation in the age-1, PI3 kinase homologue and short-term exposure to hyperoxia. | 0 | 0 |
352 | 13 | 194 | 4198 2002 FREE RADICAL BIOLOGY AND MEDICINE 32(12):1264-1275 Giasson BI; Ischiropoulos H; Lee VMY; Trojanowski JQ The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases | 2 | 41 |
353 | 13 | 42 | 4204 2002 FREE RADICAL BIOLOGY AND MEDICINE 33(8):1021-1025 Ishii N; Goto S; Hartman PS Protein oxidation during aging of the nematode Caenorhabditis elegans | 2 | 4 |
354 | 13 | 91 | 4233 2002 INCREASING HEALTHY LIFE SPAN: CONVENTIONAL MEASURES AND SLOWING THE INNATE AGING PROCESS 959:238-250 Reiter RJ; Tan DX; Manchester LC; El-Sawi M Melatonin reduces oxidant damage and promotes mitochondrial respiration - Implications for aging | 3 | 10 |
355 | 13 | 52 | 4243 2002 INCREASING HEALTHY LIFE SPAN: CONVENTIONAL MEASURES AND SLOWING THE INNATE AGING PROCESS 959:466-474 Honda Y; Honda S Oxidative stress and life span determination in the nematode Caenorhabditis elegans | 2 | 14 |
356 | 13 | 50 | 4276 2002 JOURNAL OF THE AMERICAN AGING ASSOCIATION 25(1):21-28 Honda Y; Honda S Life span extensions associated with upregulation of gene expression of antioxidant enzymes in Caenorhabditis elegans, studies of mutation in the age-1, PI3 kinase homologue and short-term exposure to hyperoxia. | 0 | 0 |
357 | 13 | 37 | 4300 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(11):1437-1446 Pamplona R; Portero-Otin M; Requena J; Gredilla R; Barja G Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls | 2 | 10 |
358 | 13 | 27 | 4310 2002 MICROSCOPY RESEARCH AND TECHNIQUE 59(4):273-277 Gredilla R; Lopez-Torres M; Barja G Effect of time of restriction on the decrease in mitochondrial H2O2 production and oxidative DNA damage in the heart of food-restricted rats | 5 | 7 |
359 | 13 | 63 | 4313 2002 MITOCHONDRION 2(1-2):27-37 Attardi G Role of mitochondrial DNA in human aging | 1 | 4 |
360 | 13 | 291 | 4399 2003 ANNALS OF HUMAN BIOLOGY 30(6):639-667 Veurink G; Fuller SJ; Atwood CS; Martins RN Genetics, lifestyle and the roles of amyloid beta and oxidative stress in Alzheimer's disease | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
361 | 13 | 41 | 4420 2003 BIOCHEMICAL SOCIETY TRANSACTIONS 31:1305-1307 Sampayo JN; Gill MS; Lithgow GJ Oxidative stress and aging - the use of superoxide dismutase/catalase mimetics to extend lifespan | 0 | 1 |
362 | 13 | 66 | 4426 2003 BIOGERONTOLOGY 4(1):19-29 Sandhu SK; Kaur G Mitochondrial electron transport chain complexes in aging rat brain and lymphocytes | 2 | 6 |
363 | 13 | 55 | 4446 2003 CELLULAR AND MOLECULAR LIFE SCIENCES 60(7):1333-1341 Nystrom T The free-radical hypothesis of aging goes prokaryotic | 0 | 0 |
364 | 13 | 43 | 4478 2003 EXPERIMENTAL GERONTOLOGY 38(8):863-876 Terman A; Dalen H; Eaton JW; Neuzil J; Brunk UT Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis | 4 | 11 |
365 | 13 | 50 | 4482 2003 EXPERIMENTAL GERONTOLOGY 38(10):1051-1063 Chen CY; Dewaele S; Braeckman B; Desmyter L; Verstraelen J; et al. A high-throughput screening system for genes extending life-span | 1 | 3 |
366 | 13 | 90 | 4553 2003 JOURNAL OF NEUROCHEMISTRY 84(5):1173-1183 Farr SA; Poon HF; Dogrukol-Ak D; Drake J; Banks WA; et al. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice | 5 | 15 |
367 | 13 | 128 | 4556 2003 JOURNAL OF NEUROCHEMISTRY 87(4):981-994 Kaufmann JA; Perez M; Zhang W; Bickford PC; Holmes DB; et al. Free radical-dependent nuclear localization of Bcl-2 in the central nervous system of aged rats is not associated with Bcl-2-mediated protection from apoptosis | 0 | 0 |
368 | 13 | 128 | 4654 2004 AGEING RESEARCH REVIEWS 3(3):265-301 Schipper HM Brain iron deposition and the free radical-mitochondrial theory of ageing | 0 | 1 |
369 | 13 | 30 | 4768 2004 EXPERIMENTAL GERONTOLOGY 39(10):1513-1519 Rebrin I; Sohal RS Comparison of thiol redox state of mitochondria and homogenates of various tissues between two strains of mice with different longevities | 0 | 0 |
370 | 13 | 66 | 4840 2004 MECHANISMS OF AGEING AND DEVELOPMENT 125(4):269-281 Romanick MA; Rakoczy SG; Brown-Borg HM Long-lived Ames dwarf mouse exhibits increased antioxidant defense in skeletal muscle | 0 | 1 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
371 | 13 | 76 | 4846 2004 MECHANISMS OF AGEING AND DEVELOPMENT 125(10-11):755-765 Szczesny B; Bhakat KK; Mitra S; Boldogh I Age-dependent modulation of DNA repair enzymes by covalent modification and subcellular distribution | 0 | 0 |
372 | 13 | 40 | 4854 2004 MOLECULAR AND CELLULAR BIOCHEMISTRY 258(1-2):145-153 Hussain AM; Mitra AK Effect of reactive oxygen species on the metabolism of tryptophan in rat brain: Influence of age | 0 | 0 |
373 | 13 | 151 | 4863 2004 NEUROSCIENCE 126(4):915-926 Poon HF; Castegna A; Farr SA; Thongboonkerd V; Lynn BC; et al. Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain | 0 | 0 |
374 | 12 | 198 | 761 1984 ARCHIVES OF GERONTOLOGY AND GERIATRICS 3(4):321-348 CUTLER RG URATE AND ASCORBATE - THEIR POSSIBLE ROLES AS ANTIOXIDANTS IN DETERMINING LONGEVITY OF MAMMALIAN-SPECIES | 13 | 42 |
375 | 12 | 38 | 937 1986 GERONTOLOGY 32(3):141-147 WADHWA R; RAI N; SHARMA SP LIFE-SPAN STUDIES IN ZAPRIONUS-PARAVITTIGER WITH SODIUM HYPOPHOSPHITE FEEDING | 7 | 10 |
376 | 12 | 94 | 1086 1988 FEBS LETTERS 241(1-2):1-5 RICHTER C DO MITOCHONDRIAL-DNA FRAGMENTS PROMOTE CANCER AND AGING | 53 | 137 |
377 | 12 | 60 | 1120 1988 NEUROCHEMICAL RESEARCH 13(5):467-478 BENZI G; PASTORIS O; VILLA RF CHANGES INDUCED BY AGING AND DRUG-TREATMENT ON CEREBRAL ENZYMATIC ANTIOXIDANT SYSTEM | 11 | 49 |
378 | 12 | 49 | 1355 1990 JOURNAL OF NUTRITION 120(6):602-609 RAO G; XIA EN; NADAKAVUKAREN MJ; RICHARDSON A EFFECT OF DIETARY RESTRICTION ON THE AGE-DEPENDENT CHANGES IN THE EXPRESSION OF ANTIOXIDANT ENZYMES IN RAT-LIVER | 34 | 103 |
379 | 12 | 50 | 1570 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(12):5360-5363 HARMAN D THE AGING PROCESS - MAJOR RISK FACTOR FOR DISEASE AND DEATH | 85 | 85 |
380 | 12 | 104 | 1601 1992 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 663:85-96 AMES BN; SHIGENAGA MK OXIDANTS ARE A MAJOR CONTRIBUTOR TO AGING | 28 | 108 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
381 | 12 | 252 | 1662 1992 CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION 32(1):1-31 JOHNSON MA; FISCHER JG; KAYS SE IS COPPER AN ANTIOXIDANT NUTRIENT | 2 | 32 |
382 | 12 | 218 | 1825 1993 ARTERY 20(2):61-94 FERNS GAA; KONNEH M; ANGGARD EE VITAMIN-E - THE EVIDENCE FOR AN ANTI-ATHEROGENICROLE | 0 | 27 |
383 | 12 | 70 | 1889 1993 HYDROBIOLOGIA 255:59-70 ENESCO HE ROTIFERS IN AGING RESEARCH - USE OF ROTIFERS TO TEST VARIOUS THEORIES OF AGING | 1 | 9 |
384 | 12 | 60 | 1971 1993 MUTATION RESEARCH 295(4-6):191-200 FEUERS RJ; WEINDRUCH R; HART RW CALORIC RESTRICTION, AGING, AND ANTIOXIDANT ENZYMES | 17 | 39 |
385 | 12 | 95 | 1974 1993 NEUROBIOLOGY OF AGING 14(4):319-330 SHARMA D; MAURYA AK; SINGH R AGE-RELATED DECLINE IN MULTIPLE-UNIT ACTION-POTENTIALS OF CA3 REGION OF RAT HIPPOCAMPUS - CORRELATION WITH LIPID-PEROXIDATION AND LIPOFUSCIN CONCENTRATION AND THE EFFECT OF CENTROPHENOXINE | 1 | 10 |
386 | 12 | 79 | 2016 1993 VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY 422(1):7-15 MULLERHOCKER J; SEIBEL P; SCHNEIDERBANGER K; KADENBACH B DIFFERENT INSITU HYBRIDIZATION PATTERNS OF MITOCHONDRIAL-DNA IN CYTOCHROME-C OXIDASE-DEFICIENT EXTRAOCULAR-MUSCLE FIBERS IN THE ELDERLY | 31 | 78 |
387 | 12 | 104 | 2056 1994 ARCHIVES OF GERONTOLOGY AND GERIATRICS 19(2):105-121 MIZUNO Y; IKEBE S; HATTORI N; MOCHIZUKI H; NAKAGAWAHATTORI Y; et al. STUDIES ON THE PATHOGENESIS OF PARKINSONS-DISEASE IN JAPAN | 0 | 1 |
388 | 12 | 61 | 2101 1994 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 108(4):501-512 BARJA G; CADENAS S; ROJAS C; LOPEZTORRES M; PEREZCAMPO R A DECREASE OF FREE-RADICAL PRODUCTION NEAR-CRITICAL TARGETS AS A CAUSE OF MAXIMUM LONGEVITY IN ANIMALS | 22 | 38 |
389 | 12 | 112 | 2226 1994 NUTRITION RESEARCH 14(7):1113-1134 VELTHUISTEWIERIK EJM; VANDENBERG H ENERGY RESTRICTION, THE BASIS FOR SUCCESSFUL AGING IN MAN | 0 | 0 |
390 | 12 | 226 | 2398 1995 FREE RADICALS AND OXIDATIVE STRESS: ENVIRONMENT, DRUGS AND FOOD ADDITIVES (61):1-31 Davies KJA Oxidative stress: The paradox of aerobic life | 2 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
391 | 12 | 38 | 2413 1995 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 27(7):647-653 RICHTER C OXIDATIVE DAMAGE TO MITOCHONDRIAL-DNA AND ITS RELATIONSHIP TO AGING | 29 | 117 |
392 | 12 | 74 | 2481 1995 MUTATION RESEARCH-DNAGING GENETIC INSTABILITY AND AGING 338(1-6):115-128 BARNETT YA; KING CM INVESTIGATION OF ANTIOXIDANT STATUS, DNA-REPAIR CAPACITY AND MUTATION AS A FUNCTION OF AGE IN HUMANS | 15 | 69 |
393 | 12 | 71 | 2572 1996 BIOESSAYS 18(10):809-815 Lithgow GJ Invertebrate gerontology: The age mutations of Caenorhabditis elegans | 5 | 52 |
394 | 12 | 100 | 2753 1996 PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS 786:152-168 Harman D A hypothesis on the pathogenesis of Alzheimer's disease | 14 | 14 |
395 | 12 | 45 | 2818 1997 ARCHIVES OF GERONTOLOGY AND GERIATRICS 24(2):103-123 Kohen R; Fanberstein D; Tirosh O Reducing equivalents in the aging process | 3 | 23 |
396 | 12 | 40 | 2831 1997 BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL 42(2):285-298 Kao SH; Liu CS; Wang SY; Wei YH Ageing-associated large-scale deletions of mitochondrial DNA in human hair follicles | 2 | 8 |
397 | 12 | 105 | 2843 1997 BIOSCIENCE REPORTS 17(3):237-250 Ozawa T Oxidative damage and fragmentation of mitochondrial DNA in cellular apoptosis | 4 | 13 |
398 | 12 | 96 | 2904 1997 GERONTOLOGY 43(1-2):132-142 Fowler CJ; Cowburn RF; Joseph JA Alzheimer's, ageing and amyloid: An absurd allegory | 0 | 5 |
399 | 12 | 43 | 2921 1997 INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 15(8):939-948 Sahoo A; Chainy GBN Alterations in the activities of cerebral antioxidant enzymes of rat are related to aging | 3 | 15 |
400 | 12 | 51 | 3021 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(21):11168-11172 Yan LJ; Levine RL; Sohal RS Oxidative damage during aging targets mitochondrial aconitase | 43 | 162 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
401 | 12 | 31 | 3164 1998 GERONTOLOGY 44(1):21-25 Martin-Aragon S; Benedi JM; Villar AM Effects of the antioxidant (6,7-dihydroxycoumarin) esculetin on the glutathione system and lipid peroxidation in mice | 2 | 10 |
402 | 12 | 183 | 3305 1998 THERAPIE 53(4):315-339 Sahnoun Z; Jamoussi K; Zeghal KM Free radicals: fundamental notions and methods of exploration (2nd part) | 0 | 14 |
403 | 12 | 42 | 3312 1998 TOWARDS PROLONGATION OF THE HEALTHY LIFE SPAN 854:171-181 Kovalenko SA; Kopsidas G; Kelso J; Rosenfeldt F; Linnane AW Tissue-specific distribution of multiple mitochondrial DNA rearrangements during human aging | 10 | 22 |
404 | 12 | 96 | 3361 1999 BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1410(2):171-182 Bonilla E; Tanji K; Hirano M; Vu TH; DiMauro S; et al. Mitochondrial involvement in Alzheimer's disease | 6 | 63 |
405 | 12 | 121 | 3384 1999 CELL 96(2):291-302 Johnson FB; Sinclair DA; Guarente L Molecular biology of aging | 34 | 166 |
406 | 12 | 84 | 3394 1999 CURRENT SCIENCE 76(1):46-54 Srinivasan V Melatonin, oxidative stress and ageing | 2 | 6 |
407 | 12 | 42 | 3434 1999 FREE RADICAL BIOLOGY AND MEDICINE 26(3-4):260-265 Lee J; Yu BP; Herlihy JT Modulation of cardiac mitochondrial membrane fluidity by age and calorie intake | 11 | 27 |
408 | 12 | 32 | 3451 1999 GERONTOLOGY 45(2):67-71 Akbulut KG; Gonul B; Akbulut H Differential effects of pharmacological doses of melatonin on malondialdehyde and glutathione levels in young and old rats | 2 | 7 |
409 | 12 | 116 | 3530 1999 MUTATION RESEARCH-DNA REPAIR 434(3):161-176 Sawyer DE; Van Houten B Repair of DNA damage in mitochondria | 3 | 43 |
410 | 12 | 46 | 3591 2000 ACTA BIOCHIMICA POLONICA 47(2):281-292 Klapcinska B; Derejczyk J; Wieczorowska-Tobis K; Sobczak A; Sadowska-Krepa E; et al. Antioxidant defense in centenarians (a preliminary study) | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
411 | 12 | 55 | 3710 2000 INTERNATIONAL JOURNAL OF SPORTS MEDICINE 21(3):154-157 Polidori MC; Mecocci P; Cherubini A; Senin U Physical activity and oxidative stress during aging | 2 | 12 |
412 | 12 | 122 | 3784 2000 MECHANISMS OF AGEING AND DEVELOPMENT 117(1-3):1-19 Turker MS Somatic cell mutations: can they provide a link between aging and cancer? | 2 | 13 |
413 | 12 | 50 | 3787 2000 MECHANISMS OF AGEING AND DEVELOPMENT 118(1-2):1-14 Tower J Transgenic methods for increasing Drosophila life span | 6 | 32 |
414 | 12 | 45 | 3795 2000 MOLECULAR AND CELLULAR GERONTOLOGY 908:14-20 Kirkwood TBL Molecular gerontology - Bridging the simple and the complex | 1 | 3 |
415 | 12 | 38 | 3858 2001 AMERICAN JOURNAL OF CHINESE MEDICINE 29(1):91-99 Lin WC; Wu YW; Lai TY; Liau MC Effect of CDA-II, urinary preparation, on lipofuscin, lipid peroxidation and antioxidant systems in young and middle-aged rat brain | 0 | 2 |
416 | 12 | 469 | 3902 2001 BRAIN RESEARCH REVIEWS 35(1):73-96 Law A; Gauthier S; Quirion R Say NO to Alzheimer's disease: the putative links between nitric oxide and dementia of the Alzheimer's type | 4 | 65 |
417 | 12 | 365 | 3921 2001 CURRENT MEDICINAL CHEMISTRY 8(7):773-796 Kovacic P; Jacintho JD Mechanisms of carcinogenesis: Focus on oxidative stress and electron transfer | 5 | 44 |
418 | 12 | 46 | 3938 2001 EXPERIMENTAL GERONTOLOGY 36(2):209-220 Kasapoglu M; Ozben T Alterations of antioxidant enzymes and oxidative stress markers in aging | 6 | 38 |
419 | 12 | 42 | 4040 2001 MECHANISMS OF AGEING AND DEVELOPMENT 122(4):427-443 Herrero A; Portero-Otin M; Bellmunt MJ; Pamplona R; Barja G Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage | 2 | 5 |
420 | 12 | 127 | 4046 2001 MICROSCOPY RESEARCH AND TECHNIQUE 52(6):689-699 Althaus HH; Mursch K; Kloppner S Differential response of mature TrkA/p75(NTR) expressing human and pig oligodendrocytes: Aging, does it matter? | 0 | 3 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
421 | 12 | 155 | 4055 2001 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 475(1-2):169-184 Berdanier CD; Everts HB Mitochondrial DNA in aging and degenerative disease | 2 | 11 |
422 | 12 | 30 | 4186 2002 EXPERIMENTAL GERONTOLOGY 37(12):1481-1487 Martin R; Fitzl G; Mozet C; Martin H; Welt K; et al. Effect of age and hypoxia/reoxygenation on mRNA expression of antioxidative enzymes in rat liver and kidneys | 0 | 0 |
423 | 12 | 104 | 4202 2002 FREE RADICAL BIOLOGY AND MEDICINE 33(5):597-604 Stadtman ER Importance of individuality in oxidative stress and aging | 4 | 17 |
424 | 12 | 44 | 4224 2002 INCREASING HEALTHY LIFE SPAN: CONVENTIONAL MEASURES AND SLOWING THE INNATE AGING PROCESS 959:50-56 Goto S; Takahashi R; Araki S; Nakamoto H Dietary restriction initiated in late adulthood can reverse age-related alterations of protein and protein metabolism | 3 | 10 |
425 | 12 | 37 | 4260 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(47):44784-44790 St-Pierre J; Buckingham JA; Roebuck SJ; Brand MD Topology of superoxide production from different sites in the mitochondrial electron transport chain | 9 | 60 |
426 | 12 | 51 | 4304 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(12):1597-1604 Yoon SO; Yun CH; Chung AS Dose effect of oxidative stress on signal transduction in aging | 1 | 6 |
427 | 12 | 90 | 4311 2002 MICROSCOPY RESEARCH AND TECHNIQUE 59(4):282-292 Avula CPR; Fernandes G Inhibition of H2O2-induced apoptosis of lymphocytes by calorie restriction during aging | 0 | 3 |
428 | 12 | 36 | 4355 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(4):1870-1875 Hagen TM; Liu JK; Lykkesfeldt J; Wehr CM; Ingersoll RT; et al. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress | 11 | 38 |
429 | 12 | 52 | 4483 2003 EXPERIMENTAL GERONTOLOGY 38(10):1129-1135 Traverso N; Patriarca S; Balbis E; Furfaro AL; Cottalasso D; et al. Anti malondialdehyde-adduct immunological response as a possible marker of successful aging | 1 | 1 |
430 | 12 | 39 | 4502 2003 FREE RADICAL BIOLOGY AND MEDICINE 34(5):546-552 Borras C; Sastre J; Garcia-Sala D; Lloret A; Pallardo FV; et al. Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males | 2 | 9 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
431 | 12 | 46 | 4520 2003 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 35(3):367-375 Okatani Y; Wakatsuki A; Reiter RJ; Miyahara Y Acutely administered melatonin restores hepatic mitochondrial physiology in old mice | 2 | 5 |
432 | 12 | 43 | 4561 2003 JOURNAL OF NUTRITION 133(11):3603-3609 Fu Y; Ji LL Chronic ginseng consumption attenuates age-associated oxidative stress in rats | 1 | 1 |
433 | 12 | 47 | 4577 2003 MECHANISMS OF AGEING AND DEVELOPMENT 124(1):49-53 Kraytsberg Y; Nekhaeva E; Bodyak NB; Khrapko K Mutation and intracellular clonal expansion of mitochondrial genomes: two synergistic components of the aging process? | 0 | 2 |
434 | 12 | 46 | 4661 2004 AGING CELL 3(5):327-330 Van Voorhies WA Live fast live long? A commentary on a recent paper by Speakman et al. | 0 | 0 |
435 | 12 | 48 | 4668 2004 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 286(5):E852-E861 Bevilacqua L; Ramsey JJ; Hagopian K; Weindruch R; Harper ME Effects of short-and medium-term calorie restriction on muscle mitochondrial proton leak and reactive oxygen species production | 0 | 4 |
436 | 12 | 74 | 4820 2004 JOURNAL OF NEURAL TRANSMISSION 111(9):1167-1182 Schuessel K; Leutner S; Cairns NJ; Muller WE; Eckert A Impact of gender on upregulation of antioxidant defence mechanisms in Alzheimer's disease brain | 0 | 0 |
437 | 12 | 96 | 4839 2004 MECHANISMS OF AGEING AND DEVELOPMENT 125(3):161-168 Droge W Autophagy and aging - importance of amino acid levels | 0 | 2 |
438 | 12 | 39 | 4850 2004 MEDICAL HYPOTHESES 62(6):1012-1020 de Grey ADNJ Falsifying falsifications: the most critical task of theoreticians in biology | 1 | 1 |
439 | 12 | 53 | 4885 2004 RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY 139(3):227-236 Dorszewska J; Adamczewska-Goncerzewicz Z Oxidative damage to DNA, p53 gene expression and p53 protein level in the process of aging in rat brain | 0 | 0 |
440 | 11 | 81 | 159 1969 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 17(8):721-& HARMAN D PROLONGATION OF LIFE - ROLE OF FREE RADICAL REACTIONS IN AGING | 125 | 125 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
441 | 11 | 26 | 240 1972 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 20(4):145-& HARMAN D BIOLOGIC CLOCK - MITOCHONDRIA | 244 | 243 |
442 | 11 | 100 | 338 1975 USPEKHI KHIMII 44(10):1914-1924 OBUKHOVA LK CHEMICAL GEROPROTECTION AND LIFETIME PROLONGATION | 7 | 13 |
443 | 11 | 54 | 366 1976 MECHANISMS OF AGEING AND DEVELOPMENT 5(2):79-98 MUNKRES KD; MINSSEN M AGING OF NEUROSPORA-CRASSA .1. EVIDENCE FOR FREE-RADICAL THEORY OF AGING FROM STUDIES OF A NATURAL-DEATH MUTANT | 17 | 44 |
444 | 11 | 32 | 386 1977 GERIATRICS 32(1):127-& KENT S DO FREE-RADICALS AND DIETARY ANTIOXIDANTS WAGE INTRACELLULAR WAR | 2 | 4 |
445 | 11 | 54 | 392 1977 JOURNAL OF CELL BIOLOGY 74(1):58-67 BALIN AK; GOODMAN DBP; RASMUSSEN H; CRISTOFALO VJ EFFECT OF OXYGEN AND VITAMIN-E ON LIFESPAN OF HUMAN DIPLOID CELLS INVITRO | 24 | 57 |
446 | 11 | 103 | 547 1980 JOURNALS OF GERONTOLOGY 35(1):45-56 LEIBOVITZ BE; SIEGEL BV ASPECTS OF FREE-RADICAL REACTIONS IN BIOLOGICAL-SYSTEMS - AGING | 72 | 203 |
447 | 11 | 260 | 695 1983 BIOCHIMICA ET BIOPHYSICA ACTA 726(1):41-80 HANSFORD RG BIOENERGETICS IN AGING | 49 | 167 |
448 | 11 | 44 | 734 1983 MUTATION RESEARCH 108(1-3):203-223 SANKARANARAYANAN K THE EFFECTS OF BUTYLATED HYDROXYTOLUENE ON RADIATION AND CHEMICALLY-INDUCED GENETIC-DAMAGE IN DROSOPHILA-MELANOGASTER | 0 | 14 |
449 | 11 | 34 | 750 1984 AGE 7(1):3-7 STOHS SJ; ELRASHIDY FH; LAWSON T; KOBAYASHI RH; WULF BG; et al. CHANGES IN GLUTATHIONE AND GLUTATHIONE METABOLIZING ENZYMES IN HUMAN-ERYTHROCYTES AND LYMPHOCYTES AS A FUNCTION OF AGE OF DONOR | 15 | 23 |
450 | 11 | 49 | 804 1984 MECHANISMS OF AGEING AND DEVELOPMENT 27(3):341-358 HEIDRICK ML; HENDRICKS LC; COOK DE EFFECT OF DIETARY 2-MERCAPTOETHANOL ON THE LIFE-SPAN, IMMUNE-SYSTEM, TUMOR-INCIDENCE AND LIPID-PEROXIDATION DAMAGE IN SPLEEN LYMPHOCYTES OF AGING BC3F1 MICE | 42 | 55 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
451 | 11 | 330 | 924 1986 ENVIRONMENTAL CARCINOGENESIS REVIEWS-PART C OF JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH 4(1):47-92 KAHL R THE DUAL ROLE OF ANTIOXIDANTS IN THE MODIFICATION OF CHEMICAL CARCINOGENESIS | 0 | 39 |
452 | 11 | 224 | 942 1986 JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY 6(3-4):25-56 FUKUZUMI K RELATIONSHIP BETWEEN LIPOPEROXIDES AND DISEASES | 1 | 6 |
453 | 11 | 137 | 1023 1987 MECHANISMS OF AGEING AND DEVELOPMENT 41(1-2):1-28 OLSON CB A REVIEW OF WHY AND HOW WE AGE - A DEFENSE OF MULTIFACTORIAL AGING | 2 | 9 |
454 | 11 | 25 | 1146 1989 AGE 12(1):19-23 ENESCO HE; WOLANSKYJ A; SAWADA M EFFECT OF COPPER ON LIFESPAN AND LIPID-PEROXIDATION IN ROTIFERS | 1 | 3 |
455 | 11 | 33 | 1288 1990 BIOCHEMICAL JOURNAL 272(1):247-250 DEQUIROGA GB; PEREZCAMPO R; TORRES ML ANTIOXIDANT DEFENSES AND PEROXIDATION IN LIVER AND BRAIN OF AGED RATS | 38 | 66 |
456 | 11 | 66 | 1385 1990 NEUROBIOLOGY OF AGING 11(5):567-571 VOLICER L; CRINO PB INVOLVEMENT OF FREE-RADICALS IN DEMENTIA OF THE ALZHEIMER TYPE - A HYPOTHESIS | 44 | 143 |
457 | 11 | 161 | 1542 1991 MEDICAL HYPOTHESES 34(3):209-219 EVANS PH; KLINOWSKI J; YANO E CEPHALOCONIOSIS - A FREE-RADICAL PERSPECTIVE ON THE PROPOSED PARTICULATE-INDUCED ETIOPATHOGENESIS OF ALZHEIMERS DEMENTIA AND RELATED DISORDERS | 4 | 15 |
458 | 11 | 70 | 1744 1992 MUTATION RESEARCH 275(3-6):115-124 MULLERHOCKER J; SCHNEIDERBANGER K; STEFANI FH; KADENBACH B PROGRESSIVE LOSS OF CYTOCHROME-C-OXIDASE IN THE HUMAN EXTRAOCULAR-MUSCLES IN AGING - A CYTOCHEMICAL-IMMUNOHISTOCHEMICAL STUDY | 16 | 61 |
459 | 11 | 70 | 1747 1992 MUTATION RESEARCH 275(3-6):157-167 ARNHEIM N; CORTOPASSI G DELETERIOUS MITOCHONDRIAL-DNA MUTATIONS ACCUMULATE IN AGING HUMAN TISSUES | 29 | 94 |
460 | 11 | 139 | 1863 1993 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 106(3):477-487 KURATA M; SUZUKI M; AGAR NS ANTIOXIDANT SYSTEMS AND ERYTHROCYTE LIFE-SPAN IN MAMMALS | 4 | 55 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
461 | 11 | 51 | 1872 1993 EXPERIMENTAL GERONTOLOGY 28(1):77-85 VERTECHY M; COOPER MB; GHIRARDI O; RAMACCI MT THE EFFECT OF AGE ON THE ACTIVITY OF ENZYMES OF PEROXIDE METABOLISM IN RAT-BRAIN | 4 | 16 |
462 | 11 | 62 | 1927 1993 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 41(2):143-148 BERR C; NICOLE A; GODIN J; CEBALLOSPICOT I; THEVENIN M; et al. SELENIUM AND OXYGEN-METABOLIZING ENZYMES IN ELDERLY COMMUNITY RESIDENTS - A PILOT EPIDEMIOLOGIC-STUDY | 10 | 32 |
463 | 11 | 29 | 2115 1994 EXPERIMENTAL GERONTOLOGY 29(5):575-584 SHI L; SAWADA M; SESTER U; CARLSON JC ALTERATIONS IN FREE-RADICAL ACTIVITY IN AGING DROSOPHILA | 3 | 11 |
464 | 11 | 56 | 2178 1994 JOURNALS OF GERONTOLOGY 49(5):B231-B238 LUHTALA TA; ROECKER EB; PUGH T; FEUERS RJ; WEINDRUCH R DIETARY RESTRICTION ATTENUATES AGE-RELATED INCREASES IN RAT SKELETAL-MUSCLE ANTIOXIDANT ENZYME-ACTIVITIES | 0 | 29 |
465 | 11 | 56 | 2214 1994 NEUROBIOLOGY OF NO- AND -OH 738:104-115 MIRAULT ME; TREMBLAY A; FURLING D; TREPANIER G; DUGRE F; et al. TRANSGENIC GLUTATHIONE-PEROXIDASE MOUSE MODELS FOR NEUROPROTECTION STUDIES | 3 | 25 |
466 | 11 | 34 | 2298 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 324(2):249-254 Dubey A; Forster MJ; Sohal RS Effect of the spin-trapping compound n-tert-butyl-alpha-phenylnitrone on protein oxidation and life span | 14 | 35 |
467 | 11 | 95 | 2360 1995 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 25:30-37 GROSSMAN LI MITOCHONDRIAL MUTATIONS AND HUMAN-DISEASE | 1 | 11 |
468 | 11 | 83 | 2463 1995 MECHANISMS OF AGEING AND DEVELOPMENT 79(1):33-57 TAYLOR A; LIPMAN RD; JAHNGENHODGE J; PALMER V; SMITH D; et al. DIETARY CALORIE RESTRICTION IN THE EMERY MOUSE - EFFECTS ON LIFE-SPAN, EYE LENS CATARACT PREVALENCE AND PROGRESSION, LEVELS OF ASCORBATE, GLUTATHIONE, GLUCOSE, AND GLYCOHEMOGLOBIN, TAIL COLLAGEN BREAKTIME, DNA AND RNA OXIDATION, SKIN INTEGRITY, FECUNDITY, AND CANCER | 4 | 36 |
469 | 11 | 35 | 2466 1995 MECHANISMS OF AGEING AND DEVELOPMENT 81(1):15-25 SOHAL RS; AGARWAL S; SOHAL BH OXIDATIVE STRESS AND AGING IN THE MONGOLIAN GERBIL (MERIONES-UNGUICULATUS) | 37 | 68 |
470 | 11 | 46 | 2483 1995 MUTATION RESEARCH-DNAGING GENETIC INSTABILITY AND AGING 338(1-6):203-213 MARTUS HJ; DOLLE MET; GOSSEN JA; BOERRIGTER METI; VIJG J USE OF TRANSGENIC MOUSE MODELS FOR STUDYING SOMATIC MUTATIONS IN AGING | 6 | 22 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
471 | 11 | 59 | 2491 1995 NEUROLOGY 45(8):1594-1601 LOVELL MA; EHMANN WD; BUTLER SM; MARKESBERY WR ELEVATED THIOBARBITURIC ACID-REACTIVE SUBSTANCES AND ANTIOXIDANT ENZYME-ACTIVITY IN THE BRAIN IN ALZHEIMERS-DISEASE | 29 | 204 |
472 | 11 | 39 | 2496 1995 NUCLEIC ACIDS RESEARCH 23(8):1419-1425 MELOV S; LITHGOW GJ; FISCHER DR; TEDESCO PM; JOHNSON TE INCREASED FREQUENCY OF DELETIONS IN THE MITOCHONDRIAL GENOME WITH AGE OF CAENORHABDITIS-ELEGANS | 14 | 36 |
473 | 11 | 49 | 2596 1996 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 114(4):361-365 Das S; Patnaik BK Effect of age and partial water deprivation on lipid peroxidation in the brain of male garden lizard | 1 | 2 |
474 | 11 | 98 | 2616 1996 EXPERIMENTAL GERONTOLOGY 31(6):623-643 Arking R; Force AG; Dudas SP; Buck S; Baker GT Factors contributing to the plasticity of the extended longevity phenotypes of Drosophila | 3 | 16 |
475 | 11 | 222 | 2644 1996 INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION 47(3):233-261 Benzie IFF Lipid peroxidation: A review of causes, consequences, measurement and dietary influences | 0 | 60 |
476 | 11 | 50 | 2650 1996 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 37(2):384-391 Barreau E; Brossas JY; Courtois Y; Treton JA Accumulation of mitochondrial DNA deletions in human retina during aging | 2 | 11 |
477 | 11 | 52 | 2695 1996 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 51(6):B392-B395 Johnson TE; Lithgow GJ; Murakami S Hypothesis: Interventions that increase the response to stress offer the potential for effective life prolongation and increased health | 0 | 44 |
478 | 11 | 221 | 2725 1996 MUTATION RESEARCH-REVIEWS IN GENETIC TOXICOLOGY 366(3):197-238 DeFlora S; Izzotti A; Randerath K; Randerath E; Bartsch H; et al. DNA adducts and chronic degenerative diseases. Pathogenetic relevance and implications in preventive medicine | 2 | 59 |
479 | 11 | 44 | 2746 1996 PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS 786:1-11 Yu BP; Yang R Critical evaluation of the free radical theory of aging - A proposal for the oxidative stress hypothesis | 25 | 42 |
480 | 11 | 206 | 2773 1996 REVIEWS IN THE NEUROSCIENCES 7(1):1-19 MeierRuge W; BertoniFreddari C The significance of glucose turnover in the brain in the pathogenetic mechanisms of Alzheimer's disease | 4 | 33 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
481 | 11 | 175 | 2774 1996 SCHIZOPHRENIA RESEARCH 19(1):1-17 Mahadik SP; Mukherjee S Free radical pathology and antioxidant defense in schizophrenia: A review | 5 | 76 |
482 | 11 | 37 | 2798 1997 AGE 20(4):221-228 Oriaku ET; Chen FX; Desai VG; Pipkin JL; Shaddock JG; et al. A circadian study of liver antioxidant enzyme systems of female Fischer-344 rats subjected to dietary restriction for six weeks. | 1 | 2 |
483 | 11 | 69 | 2933 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272(45):28652-28659 Hunter T; Bannister WH; Hunter GJ Cloning, expression, and characterization of two manganese superoxide dismutases from Caenorhabditis elegans | 8 | 16 |
484 | 11 | 155 | 2948 1997 JOURNAL OF MOLECULAR MEDICINE-JMM 75(10):703-714 ZsNagy I The membrane hypothesis of aging: its relevance to recent progress in genetic research | 5 | 14 |
485 | 11 | 43 | 2950 1997 JOURNAL OF NEUROCHEMISTRY 68(5):2061-2069 Lyras L; Cairns NJ; Jenner A; Jenner P; Halliwell B An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease | 13 | 138 |
486 | 11 | 50 | 2991 1997 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 377(1):137-147 King CM; BristowCraig HE; Gillespie ES; Barnett YA In vivo antioxidant status, DNA damage, mutation and DNA repair capacity in cultured lymphocytes from healthy 75-to 80-year-old humans | 6 | 31 |
487 | 11 | 292 | 3011 1997 PHARMACOLOGICAL REVIEWS 49(1):99-136 Villa RF; Gorini A Pharmacology of lazaroids and brain energy metabolism: A review | 2 | 23 |
488 | 11 | 58 | 3206 1998 JOURNAL OF NEUROCHEMISTRY 71(1):302-312 Lyras L; Perry RH; Perry EK; Ince PG; Jenner A; et al. Oxidative damage to proteins, lipids, and DNA in cortical brain regions from patients with dementia with Lewy bodies | 4 | 48 |
489 | 11 | 50 | 3234 1998 MECHANISMS OF AGEING AND DEVELOPMENT 101(3):245-256 Goodell S; Cortopassi G Analysis of oxygen consumption and mitochondrial permeability with age in mice | 9 | 12 |
490 | 11 | 73 | 3346 1999 AMERICAN NATURALIST 154:S67-S81 Tatar M Transgenes in the analysis of life span and fitness | 0 | 22 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
491 | 11 | 63 | 3437 1999 FREE RADICAL BIOLOGY AND MEDICINE 26(5-6):538-547 Traverso N; Menini S; Odetti P; Pronzato MA; Cottalasso D; et al. Lipoperoxidation in hepatic subcellular compartments of diabetic rats | 1 | 13 |
492 | 11 | 96 | 3452 1999 GERONTOLOGY 45(5):289-297 Meier-Ruge WA; Bertoni-Freddari C Mitochondrial genome lesions in the pathogenesis of sporadic Alzheimer's disease | 1 | 11 |
493 | 11 | 62 | 3514 1999 MECHANISMS OF AGEING AND DEVELOPMENT 110(3):157-173 Reiter RJ; Tan DX; Kim SJ; Manchester LC; Qi WB; et al. Augmentation of indices of oxidative damage in life-long melatonin-deficient rats | 17 | 54 |
494 | 11 | 51 | 3516 1999 MECHANISMS OF AGEING AND DEVELOPMENT 111(2-3):123-132 Meydani M Dietary antioxidants modulation of aging and immune-endothelial cell interaction | 7 | 17 |
495 | 11 | 97 | 3589 1999 ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE 32(2):112-123 Ahlert G Biogerontology: Present state and recent developments | 0 | 0 |
496 | 11 | 37 | 3593 2000 ACTA PHYSIOLOGICA SCANDINAVICA 169(4):343-351 Bejma J; Ramires P; Ji LL Free radical generation and oxidative stress with ageing and exercise: Differential effects in the myocardium and liver | 7 | 27 |
497 | 11 | 69 | 3600 2000 AMERICAN JOURNAL OF EPIDEMIOLOGY 151(12):1182-1188 Ford ES Serum copper concentration and coronary heart disease among US adults | 0 | 10 |
498 | 11 | 136 | 3626 2000 BIOLOGICAL SIGNALS AND RECEPTORS 9(3-4):137-159 Tan DX; Manchester LC; Reiter RJ; Qi WB; Karbownik M; et al. Significance of melatonin in antioxidative defense system: Reactions and products | 6 | 80 |
499 | 11 | 63 | 3632 2000 BRAIN RESEARCH 885(1):45-52 Mandavilli BS; Ali SF; Van Houten B DNA damage in brain mitochondria caused by aging and MPTP treatment | 2 | 12 |
500 | 11 | 50 | 3661 2000 EXPERIMENTAL GERONTOLOGY 35(2):167-185 Arking R; Burde V; Graves K; Hari R; Feldman E; et al. Forward and reverse selection for longevity in Drosophila is characterized by alteration of antioxidant gene expression and oxidative damage patterns | 8 | 32 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
501 | 11 | 75 | 3693 2000 FREE RADICAL BIOLOGY AND MEDICINE 29(12):1302-1306 Facchini FS; Hua NW; Reaven GM; Stoohs RA Hyperinsulinemia: The missing link among oxidative stress and age-related diseases? | 4 | 33 |
502 | 11 | 111 | 3716 2000 JOURNAL OF ANDROLOGY 21(2):189-199 St John JC; Sakkas D; Barratt CLR A role for mitochondrial DNA and sperm survival | 0 | 10 |
503 | 11 | 55 | 3806 2000 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 452(1):123-138 Lopez ME; Van Zeeland NL; Dahl DB; Weindruch R; Aiken JM Cellular phenotypes of age-associated skeletal muscle mitochondrial abnormalities in rhesus monkeys | 9 | 20 |
504 | 11 | 70 | 3831 2000 PSYCHIATRY RESEARCH 97(2-3):137-151 Yao JK; Reddy R; van Kammen DP Abnormal age-related changes of plasma antioxidant proteins in schizophrenia | 2 | 13 |
505 | 11 | 35 | 3866 2001 ANNALES DE BIOLOGIE CLINIQUE 59(4):453-459 Bonnefont-Rousselot D; Therond P; Beaudeux JL; Peynet J; Legrand A; et al. Aging and oxidative stress. Which potential markers? | 0 | 1 |
506 | 11 | 321 | 3867 2001 ANNALS OF CLINICAL AND LABORATORY SCIENCE 31(1):25-67 Fosslien E Review: Mitochondrial medicine - Molecular pathology of defective oxidative phosphorylation | 1 | 22 |
507 | 11 | 54 | 3950 2001 EXPERIMENTAL GERONTOLOGY 36(9):1503-1518 Linton S; Davies MJ; Dean RT Protein oxidation and ageing | 3 | 20 |
508 | 11 | 67 | 3966 2001 FREE RADICAL BIOLOGY AND MEDICINE 30(8):836-845 Palomero J; Galan AI; Munoz ME; Tunon MJ; Gonzalez-Gallego J; et al. Effects of aging on the susceptibility to the toxic effects of cyclosporin A in rats. Changes in liver glutathione and antioxidant enzymes | 2 | 9 |
509 | 11 | 37 | 3982 2001 HISTOCHEMICAL JOURNAL 33(1):43-50 Ogawa T; Ohira A; Amemiya T; Kubo N; Sato H Superoxide dismutase in senescence-accelerated mouse retina | 0 | 2 |
510 | 11 | 89 | 4014 2001 JOURNAL OF THE AMERICAN AGING ASSOCIATION 24(3):85-96 Brown-Borg H; Johnson WT; Rakoczy S; Romanick M Mitochondrial oxidant generation and oxidative damage in ames dwarf and GH transgenic mice | 3 | 5 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
511 | 11 | 47 | 4029 2001 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 56(10):B415-B425 Vettraino J; Buck S; Arking R Direct selection for paraquat resistance in Drosophila results in a different extended longevity phenotype | 0 | 11 |
512 | 11 | 44 | 4037 2001 LIPIDS 36(5):491-498 Portero-Otin M; Bellmunt MJ; Ruiz MC; Barja G; Pamplona R Correlation of fatty acid unsaturation of the major liver mitochondrial phospholipid classes in mammals to their maximum life span potential | 1 | 4 |
513 | 11 | 134 | 4062 2001 NEUROPATHOLOGY AND GENETICS OF DEMENTIA 487:229-251 Turner C; Schapira AHV Mitochondrial dysfunction in neurodegenerative disorders and ageing | 0 | 5 |
514 | 11 | 83 | 4096 2002 AGEING RESEARCH REVIEWS 1(1):79-93 McArdle A; Vasilaki A; Jackson M Exercise and skeletal muscle ageing: cellular and molecular mechanisms | 0 | 12 |
515 | 11 | 60 | 4134 2002 BIOCHEMICAL PHARMACOLOGY 64(5-6):999-1005 Holbrook NJ; Ikeyama S Age-related decline in cellular response to oxidative stress: links to growth factor signaling pathways with common defects | 3 | 13 |
516 | 11 | 66 | 4235 2002 INCREASING HEALTHY LIFE SPAN: CONVENTIONAL MEASURES AND SLOWING THE INNATE AGING PROCESS 959:308-320 Nagy IZ Pharmacological interventions against aging through the cell plasma membrane - A review of the experimental results obtained in animals and humans | 0 | 0 |
517 | 11 | 43 | 4275 2002 JOURNAL OF PINEAL RESEARCH 33(3):127-133 Okatani Y; Wakatsuki A; Reiter RJ; Miyahara Y Hepatic mitochondrial dysfunction in senescence-accelerated mice: correction by long-term, orally administered physiological levels of melatonin | 2 | 6 |
518 | 11 | 67 | 4287 2002 MARINE ECOLOGY-PROGRESS SERIES 226:223-234 Sukhotin AA; Abele D; Portner HO Growth, metabolism and lipid peroxidation in Mytilus edulis: age and size effects | 2 | 9 |
519 | 11 | 86 | 4294 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(7):791-799 Goyns MH Genes, telomeres and mammalian ageing | 1 | 6 |
520 | 11 | 48 | 4303 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(12):1553-1561 Hosokawa M A higher oxidative status accelerates senescence and aggravates age-dependent disorders in SAMP strains of mice | 1 | 3 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
521 | 11 | 79 | 4334 2002 NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS 26(6):679-695 Milgram NW; Head E; Muggenburg B; Holowachuk D; Murphey H; et al. Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy | 0 | 10 |
522 | 11 | 68 | 4356 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(4):1876-1881 Liu JK; Killilea DW; Ames BN Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha-lipoic acid | 12 | 33 |
523 | 11 | 43 | 4389 2003 AGING CELL 2(6):319-326 Sampayo JN; Olsen A; Lithgow GJ Oxidative stress in Caenorhabditis elegans: protective effects of superoxide dismutase/catalase mimetics | 1 | 2 |
524 | 11 | 146 | 4445 2003 CELL CALCIUM 34(4-5):311-323 Toescu EC; Verkhratsky A Neuronal ageing from an intraneuronal perspective: roles of endoplasmic reticulum and mitochondria | 0 | 8 |
525 | 11 | 61 | 4517 2003 HYPOXIA: THROUGH THE LIFECYCLE 543:191-200 Droge W Oxidative stress and aging | 1 | 4 |
526 | 11 | 30 | 4534 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(29):26418-26422 Orr WC; Mockett RJ; Benes JJ; Sohal RS Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster | 4 | 11 |
527 | 11 | 46 | 4567 2003 JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION 22(3):232-238 Wouters-Wesseling W; Wagenaar LW; de Groot LCPGM; Bindels JG; van Staveren WA Biochemical antioxidant levels respond to supplementation with an enriched drink in frail elderly people | 0 | 0 |
528 | 11 | 50 | 4686 2004 BIOCHEMICAL JOURNAL 380:919-928 Hutter E; Renner K; Pfister G; Stockl P; Jansen-Durr P; et al. Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts | 0 | 0 |
529 | 11 | 48 | 4698 2004 BIOLOGICAL & PHARMACEUTICAL BULLETIN 27(4):475-479 Kamiya H Mutagenicities of 8-hydroxyguanine and 2-hydroxyadenine produced by reactive oxygen species | 0 | 0 |
530 | 11 | 145 | 4733 2004 CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION 44(4):275-295 Willcox JK; Ash SL; Catignani GL Antioxidants and prevention of chronic disease | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
531 | 11 | 42 | 4754 2004 EXPERIMENTAL GERONTOLOGY 39(2):189-194 Quiles JL; Ochoa JJ; Huertas JR; Mataix J Coenzyme Q supplementation protects from age-related DNA double-strand breaks and increases lifespan in rats fed on a PUFA-rich diet | 1 | 1 |
532 | 11 | 37 | 4760 2004 EXPERIMENTAL GERONTOLOGY 39(5):725-733 Pamplona R; Portero-Otin M; Sanz A; Requena J; Barja G Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain | 0 | 1 |
533 | 11 | 50 | 4766 2004 EXPERIMENTAL GERONTOLOGY 39(9):1391-1400 Gianni P; Jan KJ; Douglas MJ; Stuart PM; Tarnopolsky MA Oxidative stress and the mitochondrial theory of aging in human skeletal muscle | 0 | 0 |
534 | 11 | 39 | 4769 2004 EXPERIMENTAL GERONTOLOGY 39(10):1527-1535 Portero-Otin M; Requena JR; Bellmunt MJ; Ayala V; Pamplona R Protein nonenzymatic modifications and proteasome activity in skeletal muscle from the short-lived rat and long-lived pigeon | 0 | 0 |
535 | 11 | 94 | 4778 2004 FREE RADICAL BIOLOGY AND MEDICINE 36(8):1043-1057 Lee CK; Pugh TD; Klopp RG; Edwards J; Allison DB; et al. The impact of alpha-lipoic acid, coenzyme Q(10), and caloric restriction on life span and gene expression patterns in mice | 0 | 0 |
536 | 11 | 79 | 4838 2004 MECHANISMS OF AGEING AND DEVELOPMENT 125(1):21-30 Minogue PJ; Thomas JN An alpha-tocopherol dose response study in Paramecium tetraurelia | 0 | 0 |
537 | 11 | 71 | 4909 2005 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 288(1):H371-H381 Kanski J; Behring A; Pelling J; Schoneich C Proteomic identification of 3-nitrotyrosine-containing rat cardiac proteins: effects of biological aging | 0 | 0 |
538 | 10 | 68 | 202 1971 EXPERIMENTAL GERONTOLOGY 6(2):153-& HOCHSCHI.R LYSOSOMES, MEMBRANES AND AGING | 0 | 61 |
539 | 10 | 64 | 562 1980 OLEAGINEUX 35(11):511-514 FUKUZUMI K AGING IN RELATION TO LIPIDS - LIPOPEROXIDE, ESSENTIAL FATTY-ACIDS, VITAMIN-E | 1 | 1 |
540 | 10 | 52 | 606 1981 OLEAGINEUX 36(5):251-253 FUKUZUMI K RELATIONSHIP BETWEEN LIPOPEROXIDE AND AGING | 1 | 2 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
541 | 10 | 48 | 740 1983 RADIATION RESEARCH 95(3):637-645 DE AK; CHIPALKATTI S; AIYAR AS EFFECTS OF CHRONIC IRRADIATION ON AGE-RELATED BIOCHEMICAL-CHANGES IN MICE | 2 | 10 |
542 | 10 | 23 | 855 1985 INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY 23(2):83-87 ISLAM MS; NESSA A GAMMA-RAY INDUCED AGING MUTANTS OF NEUROSPORA-CRASSA - RESPONSE TO SOME ANTIOXIDANTS AND CHLORAMPHENICOL | 0 | 0 |
543 | 10 | 31 | 1169 1989 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 164(2):620-625 SEMSEI I; RAO G; RICHARDSON A CHANGES IN THE EXPRESSION OF SUPEROXIDE-DISMUTASE AND CATALASE AS A FUNCTION OF AGE AND DIETARY RESTRICTION | 45 | 104 |
544 | 10 | 161 | 1321 1990 EXPERIMENTAL GERONTOLOGY 25(6):499-522 SOHAL RS; ALLEN RG OXIDATIVE STRESS AS A CAUSAL FACTOR IN DIFFERENTIATION AND AGING - A UNIFYING HYPOTHESIS | 62 | 136 |
545 | 10 | 51 | 1341 1990 JOURNAL OF CELLULAR BIOCHEMISTRY 44(3):153-165 SAWADA M; CARLSON JC BIOCHEMICAL-CHANGES ASSOCIATED WITH THE MECHANISM CONTROLLING SUPEROXIDE RADICAL FORMATION IN THE AGING ROTIFER | 11 | 15 |
546 | 10 | 35 | 1361 1990 JOURNALS OF GERONTOLOGY 45(5):B141-B147 HARRIS SB; WEINDRUCH R; SMITH GS; MICKEY MR; WALFORD RL DIETARY RESTRICTION ALONE AND IN COMBINATION WITH ORAL ETHOXYQUIN 2-MERCAPTOETHYLAMINE IN MICE | 0 | 8 |
547 | 10 | 50 | 1368 1990 MECHANISMS OF AGEING AND DEVELOPMENT 53(1):49-60 RAO G; XIA E; RICHARDSON A EFFECT OF AGE ON THE EXPRESSION OF ANTIOXIDANT ENZYMES IN MALE FISCHER-F344 RATS | 50 | 104 |
548 | 10 | 30 | 1487 1991 EXPERIMENTAL GERONTOLOGY 26(4):385-395 SESTINI EA; CARLSON JC; ALLSOPP R THE EFFECTS OF AMBIENT-TEMPERATURE ON LIFE-SPAN, LIPID-PEROXIDATION, SUPEROXIDE-DISMUTASE, AND PHOSPHOLIPASE-A2 ACTIVITY IN DROSOPHILA-MELANOGASTER | 5 | 10 |
549 | 10 | 33 | 1535 1991 MECHANISMS OF AGEING AND DEVELOPMENT 59(1-2):123-128 DE AK; DARAD R AGE-ASSOCIATED CHANGES IN ANTIOXIDANTS AND ANTIOXIDATIVE ENZYMES IN RATS | 6 | 22 |
550 | 10 | 36 | 1536 1991 MECHANISMS OF AGEING AND DEVELOPMENT 59(1-2):129-137 LOPEZTORRES M; PEREZCAMPO R; DEQUIROGA GB AGING IN BROWN FAT - ANTIOXIDANT DEFENSES AND OXIDATIVE STRESS | 1 | 1 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
551 | 10 | 138 | 1645 1992 CARDIOSCIENCE 3(2):67-78 MUSCARI C; CALDARERA I; RAPEZZI C; BRANZI A; CALDARERA CM BIOCHEMICAL CORRELATES WITH MYOCARDIAL AGING | 0 | 12 |
552 | 10 | 52 | 1681 1992 FREE RADICAL RESEARCH COMMUNICATIONS 17(1):73-85 REVEILLAUD I; KONGPACHITH A; PARK R; FLEMING JE STRESS RESISTANCE OF DROSOPHILA TRANSGENIC FOR BOVINE CUZN SUPEROXIDE-DISMUTASE | 3 | 5 |
553 | 10 | 80 | 1758 1992 MUTATION RESEARCH 275(3-6):405-414 GILLE JJP; JOENJE H CELL-CULTURE MODELS FOR OXIDATIVE STRESS - SUPEROXIDE AND HYDROGEN-PEROXIDE VERSUS NORMOBARIC HYPEROXIA | 5 | 55 |
554 | 10 | 341 | 1770 1992 PHARMACOLOGY & THERAPEUTICS 53(1):127-166 FRENKEL K CARCINOGEN-MEDIATED OXIDANT FORMATION AND OXIDATIVE DNA DAMAGE | 16 | 213 |
555 | 10 | 64 | 1776 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(19):9112-9116 YOUNGMAN LD; PARK JYK; AMES BN PROTEIN OXIDATION ASSOCIATED WITH AGING IS REDUCED BY DIETARY RESTRICTION OF PROTEIN OR CALORIES | 41 | 129 |
556 | 10 | 124 | 1789 1993 AGE 16(1):23-30 HARMAN D FREE-RADICAL THEORY OF AGING - A HYPOTHESIS ON PATHOGENESIS OF SENILE DEMENTIA OF THE ALZHEIMER TYPE | 39 | 39 |
557 | 10 | 53 | 1864 1993 COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES 187(3):308-323 CEBALLOSPICOT I TRANSGENIC MICE OVEREXPRESSING COPPER-ZINC SUPEROXIDE-DISMUTASE AS MODELS FOR THE STUDY OF FREE-RADICALS METABOLISM AND AGING | 2 | 6 |
558 | 10 | 38 | 1878 1993 FREE RADICAL BIOLOGY AND MEDICINE 15(2):133-142 LOPEZTORRES M; PEREZCAMPO R; ROJAS C; CADENAS S; BARJA G SIMULTANEOUS INDUCTION OF SOD, GLUTATHIONE-REDUCTASE, GSH, AND ASCORBATE IN LIVER AND KIDNEY CORRELATES WITH SURVIVAL DURING AGING | 28 | 56 |
559 | 10 | 114 | 1888 1993 HUMAN GENETICS 91(6):519-526 SCHACHTER F; COHEN D; KIRKWOOD T PROSPECTS FOR THE GENETICS OF HUMAN LONGEVITY | 4 | 56 |
560 | 10 | 50 | 1949 1993 MECHANISMS OF AGEING AND DEVELOPMENT 70(1-2):65-82 IANTOMASI T; FAVILLI F; MARRACCINI P; STIO M; TREVES C; et al. AGE AND GSH METABOLISM IN RAT CEREBRAL-CORTEX, AS RELATED TO OXIDATIVE AND ENERGY PARAMETERS | 2 | 14 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
561 | 10 | 56 | 2017 1993 VIRCHOWS ARCHIV B-CELL PATHOLOGY INCLUDING MOLECULAR PATHOLOGY 63(3):139-146 BEIER K; VOLKL A; FAHIMI HD THE IMPACT OF AGING ON ENZYME PROTEINS OF RAT-LIVER PEROXISOMES - QUANTITATIVE-ANALYSIS BY IMMUNOBLOTTING AND IMMUNOELECTRON MICROSCOPY | 6 | 25 |
562 | 10 | 99 | 2057 1994 ARCHIVES OF GERONTOLOGY AND GERIATRICS 19(2):159-170 GOTO S MOLECULAR BIOLOGICAL APPROACHES TO AGING IN JAPAN - AN OVERVIEW | 0 | 2 |
563 | 10 | 44 | 2099 1994 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-PHYSIOLOGY 108(2-3):315-323 DUMONT E; CHICHERY MP; NOUVELOT A; CHICHERY R VARIATIONS OF THE LIPID CONSTITUENTS IN THE CENTRAL-NERVOUS-SYSTEM OF THE CUTTLEFISH (SEPIA-OFFICINALIS) DURING AGING | 0 | 1 |
564 | 10 | 35 | 2187 1994 MECHANISMS OF AGEING AND DEVELOPMENT 74(1-2):121-133 SOHAL RS; KU HH; AGARWAL S; FORSTER MJ; LAL H OXIDATIVE DAMAGE, MITOCHONDRIAL OXIDANT GENERATION AND ANTIOXIDANT DEFENSES DURING AGING AND IN RESPONSE TO FOOD RESTRICTION IN THE MOUSE | 118 | 283 |
565 | 10 | 44 | 2191 1994 MECHANISMS OF AGEING AND DEVELOPMENT 76(2-3):73-88 CASTELLUCCIO C; BARACCA A; FATO R; PALLOTTI F; MARANESI M; et al. MITOCHONDRIAL ACTIVITIES OF RAT-HEART DURING AGING | 4 | 17 |
566 | 10 | 267 | 2204 1994 MOLECULAR REPRODUCTION AND DEVELOPMENT 37(3):345-362 CUMMINS JM; JEQUIER AM; KAN R MOLECULAR-BIOLOGY OF HUMAN MALE-INFERTILITY - LINKS WITH AGING, MITOCHONDRIAL GENETICS, AND OXIDATIVE STRESS | 3 | 93 |
567 | 10 | 107 | 2231 1994 PATHOLOGIE BIOLOGIE 42(4):313-321 TOUSSAINT O; REMACLE J REVIEW OF THE THEORIES OF CELLULAR AGING - FROM HAYFLICKS CONCEPT TO THE CONCEPT OF CRITICAL THRESHOLD OF ERROR ACCUMULATION - AN UPDATED REVIEW | 1 | 2 |
568 | 10 | 109 | 2253 1994 PROCEEDINGS OF THE NUTRITION SOCIETY 53(2):431-442 EVANS PH NUTRIENT AND TOXIN INTERACTIONS IN NEURODEGENERATIVE DISEASE | 0 | 2 |
569 | 10 | 271 | 2324 1995 BIOCHIMIE 77(3):147-161 MARTINEZCAYUELA M OXYGEN-FREE RADICALS AND HUMAN-DISEASE | 3 | 80 |
570 | 10 | 36 | 2369 1995 EXPERIMENTAL CELL RESEARCH 217(2):272-279 SAITO H; HAMMOND AT; MOSES RE THE EFFECT OF LOW-OXYGEN TENSION ON THE IN-VITRO REPLICATIVE LIFE-SPAN OF HUMAN-DIPLOID FIBROBLAST CELLS AND THEIR TRANSFORMED DERIVATIVES | 6 | 46 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
571 | 10 | 38 | 2396 1995 FREE RADICAL BIOLOGY AND MEDICINE 19(6):859-865 TIAN LQ; CAI QY; BOWEN R; WEI HC EFFECTS OF CALORIC RESTRICTION ON AGE-RELATED OXIDATIVE MODIFICATIONS OF MACROMOLECULES AND LYMPHOCYTE-PROLIFERATION IN RATS | 2 | 18 |
572 | 10 | 49 | 2480 1995 MUTATION RESEARCH-DNAGING GENETIC INSTABILITY AND AGING 338(1-6):19-23 MORLEY AA THE SOMATIC MUTATION THEORY OF AGING | 6 | 22 |
573 | 10 | 60 | 2487 1995 NEUROBIOLOGY OF AGING 16(4):607-612 JOSEPH JA; ALGERI S; DECESARE A; COMUZIO M; ERAT S; et al. A REDUCED CALORIE-HIGH FIBER DIET RETARDS AGE-ASSOCIATED DECREASES IN MUSCARINIC RECEPTOR SENSITIVITY | 1 | 5 |
574 | 10 | 51 | 2528 1996 AGE 19(2):59-68 Macauley JB Current approaches to somatic mutation testing in aging research | 0 | 0 |
575 | 10 | 35 | 2532 1996 AGING-CLINICAL AND EXPERIMENTAL RESEARCH 8(2):123-129 Kim JD; McCarter RJM; Yu BP Influence of age, exercise, and dietary restriction on oxidative stress in rats | 10 | 39 |
576 | 10 | 28 | 2537 1996 AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 154(4):1141-1145 Fahn HJ; Wang LS; Hsieh RH; Chang SC; Kao SH; et al. Age-related 4,977 bp deletion in human lung mitochondrial DNA | 8 | 20 |
577 | 10 | 52 | 2629 1996 FREE RADICAL BIOLOGY AND MEDICINE 20(6):821-830 Joseph JA; VillalobosMolina R; Denisova N; Erat S; Cutler R; et al. Age differences in sensitivity to H2O2-or NO-induced reductions in K+- evoked dopamine release from superfused striatal slices: Reversals by PBN or Trolox | 5 | 39 |
578 | 10 | 55 | 2647 1996 INTERNATIONAL JOURNAL OF TISSUE REACTIONS-EXPERIMENTAL AND CLINICAL ASPECTS 18(1):33-41 Montanari G; Giamberardino MA; Corbucci GG; Marchionni A; Vecchiet L Muscle cell and oxidative damage in aging: A century of hypothesis and personal contribution | 0 | 0 |
579 | 10 | 99 | 2738 1996 NUTRITION REVIEWS 54(3):73-84 Sempos CT; Looker AC; Gillum RF Iron and heart disease: The epidemiologic data | 1 | 58 |
580 | 10 | 490 | 2767 1996 PROGRESS IN LIPID RESEARCH 35(4):409-457 Okuyama H; Kobayashi T; Watanabe S Dietary fatty acids - The N-6/N-3 balance and chronic elderly diseases. Excess linoleic acid and relative N-3 deficiency syndrome seen in Japan | 0 | 17 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
581 | 10 | 57 | 2899 1997 FREE RADICAL BIOLOGY AND MEDICINE 23(2):191-201 Gabbita SP; Butterfield DA; Hensley K; Shaw W; Carney JM Aging and caloric restriction affect mitochondrial respiration and lipid membrane status: An electron paramagnetic resonance investigation | 13 | 37 |
582 | 10 | 35 | 2932 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272(31):19199-19204 Lass A; Agarwal S; Sohal RS Mitochondrial ubiquinone homologues, superoxide radical generation, and longevity in different mammalian species | 5 | 42 |
583 | 10 | 28 | 2954 1997 JOURNAL OF PHARMACY AND PHARMACOLOGY 49(1):49-52 MartinAragon S; Benedi JM; Villar AM Modifications on antioxidant capacity and lipid peroxidation in mice under fraxetin treatment | 3 | 14 |
584 | 10 | 41 | 2956 1997 JOURNAL OF RADIATION RESEARCH 38(2):121-131 MurataKamiya N; Kamiya H; Muraoka M; Kaji H; Kasai H Comparison of oxidation products from DNA components by gamma-irradiation and Fenton-type reactions | 8 | 38 |
585 | 10 | 20 | 2977 1997 MECHANISMS OF AGEING AND DEVELOPMENT 98(2):177-180 DogruAbbasoglu S; TamerToptani S; Ugurnal B; KocakToker N; AykacToker G; et al. Lipid peroxidation and antioxidant enzymes in livers and brains of aged rats | 9 | 18 |
586 | 10 | 51 | 2982 1997 MEDICAL HYPOTHESES 48(5):387-392 Challem JJ Did the loss of endogenous ascorbate propel the evolution of Anthropoidea and Homo sapiens? | 1 | 6 |
587 | 10 | 156 | 2986 1997 MOLECULAR AND CELLULAR BIOCHEMISTRY 174(1-2):305-319 Papa S; Skulachev VP Reactive oxygen species, mitochondria, apoptosis and aging | 20 | 121 |
588 | 10 | 45 | 3018 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(2):674-678 Butterfield DA; Howard BJ; Yatin S; Allen KL; Carney JM Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone | 26 | 112 |
589 | 10 | 94 | 3024 1997 PROGRESS IN LIPID RESEARCH 36(1):1-21 Morrow JD; Roberts LJ The isoprostanes: Unique bioactive products of lipid peroxidation | 16 | 198 |
590 | 10 | 29 | 3026 1997 PROSTATE 33(4):256-263 Suzuki K; Oberley TD; Pugh TD; Sempf JM; Weindruch R Caloric restriction diminishes the age-associated loss of immunoreactive catalase in rat prostate | 0 | 2 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
591 | 10 | 132 | 3066 1998 APMIS 106(2):265-276 Terman A; Brunk UT Lipofuscin: Mechanisms of formation and increase with age | 11 | 60 |
592 | 10 | 49 | 3096 1998 BRITISH JOURNAL OF PHARMACOLOGY 123(1):113-121 Rodriguez-Martinez MA; Alonso MJ; Redondo; J; Salaices M; et al. Role of lipid peroxidation and the glutathione-dependent antioxidant system in the impairment of endothelium-dependent relaxations with age | 2 | 25 |
593 | 10 | 25 | 3158 1998 FREE RADICAL RESEARCH 29(6):573-579 Hudson EK; Hogue BA; Souza-Pinto NC; Croteau DL; Anson RM; et al. Age-associated change in mitochondrial DNA damage | 9 | 31 |
594 | 10 | 34 | 3227 1998 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 53(4):B240-B244 Adachi H; Fujiwara Y; Ishii N Effects of oxygen on protein carbonyl and aging in Caenorhabditis elegans mutants with long (age-1) and short (mev-1) life spans | 0 | 31 |
595 | 10 | 48 | 3237 1998 MECHANISMS OF AGEING AND DEVELOPMENT 103(1):69-80 Ashok BT; Ali R Binding of circulating antibodies to reactive oxygen species modified-DNA and detecting DNA damage by a monoclonal antibody probe | 1 | 7 |
596 | 10 | 62 | 3270 1998 NUCLEIC ACIDS RESEARCH 26(7):1621-1627 Tawe WN; Eschbach ML; Walter RD; Henkle-Duhrsen K Identification of stress-responsive genes in Caenorhabditis elegans using RT-PCR differential display | 6 | 22 |
597 | 10 | 48 | 3287 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(22):12896-12901 Yan LJ; Sohal RS Mitochondrial adenine nucleotide translocase is modified oxidatively during aging | 22 | 92 |
598 | 10 | 77 | 3322 1998 TOWARDS PROLONGATION OF THE HEALTHY LIFE SPAN 854:410-424 Reiter RJ; Guerrero JM; Garcia JJ; Acuna-Castroviejo D Reactive oxygen intermediates, molecular damage, and aging - Relation to melatonin | 7 | 62 |
599 | 10 | 25 | 3332 1999 ACTA PHARMACOLOGICA SINICA 20(9):824-828 Shang YZ; Ye JW; Tang XC Improving effects of huperzine A on abnormal lipid peroxidation and superoxide dismutase in aged rats | 0 | 11 |
600 | 10 | 49 | 3375 1999 BRAIN RESEARCH 842(1):224-229 Zhu HY; Guo Q; Mattson MP Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation | 3 | 56 |
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