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#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
301	9	37	1056 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88 (17): 7749-7753 SUSSEL L; SHORE D SEPARATION OF TRANSCRIPTIONAL ACTIVATION AND SILENCING FUNCTIONS OF THE RAP1-ENCODED REPRESSOR ACTIVATOR PROTEIN-1 - ISOLATION OF VIABLE MUTANTS AFFECTING BOTH SILENCING AND TELOMERE LENGTH	73	168
302	1	28	1345 1993 JOURNAL OF VIROLOGY 67 (11): 6507-6512 WANG GH; SEEGER C NOVEL MECHANISM FOR REVERSE TRANSCRIPTION IN HEPATITIS-B VIRUSES	3	168
303	18	30	2018 1996 NATURE GENETICS 13 (3): 350-353 Metcalfe JA; Parkhill J; Campbell L; Stacey M; Biggs P; et al. Accelerated telomere shortening in ataxia telangiectasia	89	168
304	4	52	236 1984 MOLECULAR AND CELLULAR BIOLOGY 4 (11): 2455-2466 CELNIKER SE; SWEDER K; SRIENC F; BAILEY JE; CAMPBELL JL DELETION MUTATIONS AFFECTING AUTONOMOUSLY REPLICATING SEQUENCE ARS1 OF SACCHAROMYCES-CEREVISIAE	13	167
305	9	54	830 1990 GENES & DEVELOPMENT 4 (4): 503-514 CHASMAN DI; LUE NF; BUCHMAN AR; LAPOINTE JW; LORCH Y; et al. A YEAST PROTEIN THAT INFLUENCES THE CHROMATIN STRUCTURE OF UASG AND FUNCTIONS AS A POWERFUL AUXILIARY GENE ACTIVATOR	2	167
306	8	21	241 1984 NATURE 310 (5973): 157-160 WALMSLEY RM; CHAN CSM; TYE BK; PETES TD UNUSUAL DNA-SEQUENCES ASSOCIATED WITH THE ENDS OF YEAST CHROMOSOMES	138	166
307	46	93	4627 2002 SCIENCE 297 (5581): 565-569 Maser RS; DePinho RA Connecting chromosomes, crisis, and cancer	79	166
308	5	122	192 1983 NATURE 305 (5933): 391-397 STRUHL K THE NEW YEAST GENETICS	7	165
309	29	74	3062 1999 GENETICS 152 (1): 143-152 Le S; Moore JK; Haber JE; Greider CW RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase	123	165
310	17	21	3277 1999 SCIENCE 286 (5437): 117-120 Evans SK; Lundblad V Est1 and Cdc13 as comediators of telomerase access	148	165
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
311	1	27	86 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75 (9): 4271-4275 ZURAWSKI G; BROWN K; KILLINGLY D; YANOFSKY C NUCLEOTIDE-SEQUENCE OF LEADER REGION OF PHENYLALANINE OPERON OF ESCHERICHIA-COLI	6	164
312	3	91	1298 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 212 (1): 1-11 WILLIS IM RNA POLYMERASE-III - GENES, FACTORS AND TRANSCRIPTIONAL SPECIFICITY	1	164
313	9	73	1492 1994 JOURNAL OF CELL BIOLOGY 125 (3): 517-530 GUACCI V; HOGAN E; KOSHLAND D CHROMOSOME CONDENSATION AND SISTER-CHROMATID PAIRING IN BUDDING YEAST	6	164
314	21	27	2170 1997 CANCER RESEARCH 57 (4): 610-614 Kyo S; Takakura M; Kohama T; Inoue M Telomerase activity in human endometrium	105	164
315	3	63	3383 2000 CELL 103 (7): 1143-1154 Brodersen DE; Clemons WM; Carter AP; Morgan-Warren RJ; Wimberly BT; et al. The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit	4	164
316	82	144	4577 2002 ONCOGENE 21 (4): 598-610 Henson JD; Neumann AA; Yeager TR; Reddel RR Alternative lengthening of telomeres in mammalian cells	115	164
317	1	61	417 1986 MOLECULAR AND CELLULAR BIOLOGY 6 (11): 3722-3733 SCHATZ PJ; SOLOMON F; BOTSTEIN D GENETICALLY ESSENTIAL AND NONESSENTIAL ALPHA-TUBULIN GENES SPECIFY FUNCTIONALLY INTERCHANGEABLE PROTEINS	3	163
318	27	61	807 1990 CELL 61 (4): 663-673 BIESSMANN H; MASON JM; FERRY K; DHULST M; VALGEIRSDOTTIR K; et al. ADDITION OF TELOMERE-ASSOCIATED HET DNA-SEQUENCES HEALS BROKEN CHROMOSOME ENDS IN DROSOPHILA	107	162
319	1	149	1076 1992 ANNUAL REVIEW OF BIOCHEMISTRY 61: 251-281 LINDAHL T; BARNES DE MAMMALIAN DNA LIGASES	3	162
320	21	46	2154 1997 BLOOD 90 (1): 182-193 Engelhardt M; Kumar R; Albanell J; Pettengell R; Han W; et al. Telomerase regulation, cell cycle, and telomere stability in primitive hematopoietic cells	86	162
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
321	3	43	562 1988 CELL 54 (5): 705-711 BROWN TC; JIRICNY J DIFFERENT BASE BASE MISPAIRS ARE CORRECTED WITH DIFFERENT EFFICIENCIES AND SPECIFICITIES IN MONKEY KIDNEY-CELLS	0	161
322	12	52	1384 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90 (8): 3393-3397 SUNDQUIST WI; HEAPHY S EVIDENCE FOR INTERSTRAND QUADRUPLEX FORMATION IN THE DIMERIZATION OF HUMAN IMMUNODEFICIENCY VIRUS-1 GENOMIC RNA	52	161
323	36	45	947 1991 CELL 67 (4): 823-832 YU GL; BLACKBURN EH DEVELOPMENTALLY PROGRAMMED HEALING OF CHROMOSOMES BY TELOMERASE IN TETRAHYMENA	160	160
324	13	48	4153 2001 TRENDS IN BIOCHEMICAL SCIENCES 26 (3): 174-179 Smith S The world according to PARP	14	160
325	18	65	942 1991 CELL 67 (2): 343-353 ROMERO DP; BLACKBURN EH A CONSERVED SECONDARY STRUCTURE FOR TELOMERASE RNA	159	159
326	0	0	1803 1995 TELOMERES BLACKBURN EH; GREIDER CW Telomeres (Monograph 29), edited by Elizabeth H. Blackburn and Carol W. Greider.	159	159
327	37	56	1911 1996 GENES & DEVELOPMENT 10 (14): 1822-1834 McEachern MJ; Blackburn EH Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase	159	159
328	25	51	933 1991 BIOCHEMISTRY 30 (18): 4460-4472 HARDIN CC; HENDERSON E; WATSON T; PROSSER JK MONOVALENT CATION INDUCED STRUCTURAL TRANSITIONS IN TELOMERIC DNAS - G-DNA FOLDING INTERMEDIATES	97	157
329	9	29	2428 1997 SCIENCE 275 (5305): 1478-1481 Kirk KE; Harmon BP; Reichardt IK; Sedat JW; Blackburn EH Block in anaphase chromosome separation caused by a telomerase template mutation	157	157
330	15	32	3463 2000 GENES & DEVELOPMENT 14 (22): 2807-2812 Hsu HL; Gilley D; Galande SA; Hande MP; Allen B; et al. Ku acts in a unique way at the mammalian telomere to prevent end joining	122	157
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
331	18	123	4542 2002 NEW ENGLAND JOURNAL OF MEDICINE 347 (20): 1593-1603 Hahn WC; Weinberg RA Mechanisms of disease: Rules for making human tumor cells.	4	157
332	11	49	1357 1993 MOLECULAR AND CELLULAR BIOLOGY 13 (7): 4301-4310 ISHIKAWA F; MATUNIS MJ; DREYFUSS G; CECH TR NUCLEAR PROTEINS THAT BIND THE PREMESSENGER RNA 3' SPLICE-SITE SEQUENCE R(UUAG/G) AND THE HUMAN TELOMERIC DNA-SEQUENCE D(TTAGGG)N	63	156
333	1	40	205 1984 AMERICAN JOURNAL OF HUMAN GENETICS 36 (2): 265-276 WIEACKER P; DAVIES KE; COOKE HJ; PEARSON PL; WILLIAMSON R; et al. TOWARD A COMPLETE LINKAGE MAP OF THE HUMAN CHROMOSOME-X - REGIONAL ASSIGNMENT OF 16 CLONED SINGLE-COPY DNA-SEQUENCES EMPLOYING A PANEL OF SOMATIC-CELL HYBRIDS	1	155
334	5	17	2022 1996 NUCLEIC ACIDS RESEARCH 24 (4): 582-585 Porter SE; Greenwell PW; Ritchie KB; Petes TD The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae	85	155
335	29	35	2804 1998 ONCOGENE 16 (13): 1723-1730 Greenberg RA; Allsopp RC; Chin L; Morin GB; DePinho RA Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation	100	155
336	32	49	3186 1999 MOLECULAR AND CELLULAR BIOLOGY 19 (12): 8083-8093 Teng SC; Zakian VA Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae	144	155
337	18	38	3435 2000 EMBO REPORTS 1 (3): 244-252 Samper E; Goytisolo FA; Slijepcevic P; van Buul PPW; Blasco MA Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang	126	155
338	22	42	1209 1992 NUCLEIC ACIDS RESEARCH 20 (15): 4061-4067 BALAGURUMOORTHY P; BRAHMACHARI SK; MOHANTY D; BANSAL M; SASISEKHARAN V HAIRPIN AND PARALLEL QUARTET STRUCTURES FOR TELOMERIC SEQUENCES	74	154
339	8	93	2390 1997 NUCLEIC ACIDS RESEARCH 25 (12): 2245-2253 Mitas M Trinucleotide repeats associated with human disease	6	154
340	19	30	2771 1998 NATURE GENETICS 18 (1): 76-80 Martens UM; Zijlmans JMJM; Poon SSS; Dragowska W; Yui J; et al. Short telomeres on human chromosome 17p	92	154
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
341	0	33	294 1985 JOURNAL OF INFECTIOUS DISEASES 152 (1): 64-73 NASH TE; MCCUTCHAN T; KEISTER D; DAME JB; CONRAD JD; et al. RESTRICTION-ENDONUCLEASE ANALYSIS OF DNA FROM 15 GIARDIA ISOLATES OBTAINED FROM HUMANS AND ANIMALS	2	153
342	5	49	2216 1997 EMBO JOURNAL 16 (15): 4788-4795 Teo SH; Jackson SP Identification of Saccharomyces cerevisiae DNA ligase .4. Involvement in DNA double-strand break repair	18	153
343	10	42	3647 2000 NATURE MEDICINE 6 (9): 1011-1017 Nair SK; Heiser A; Boczkowski D; Majumdar A; Naoe M; et al. Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.	27	153
344	15	31	4075 2001 NATURE GENETICS 28 (2): 155-159 Rudolph KL; Millard M; Bosenberg MW; DePinho RA Telomere dysfunction and evolution of intestinal carcinoma in mice and humans	94	153
345	15	32	2059 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93 (12): 6091-6095 Zhu XL; Kumar R; Mandal M; Sharma N; Sharma HW; et al. Cell cycle-dependent modulation of telomerase activity in tumor cells	98	152
346	3	53	318 1985 NUCLEIC ACIDS RESEARCH 13 (2): 415-433 HELFTENBEIN E NUCLEOTIDE-SEQUENCE OF A MACRONUCLEAR DNA MOLECULE CODING FOR ALPHA-TUBULIN FROM THE CILIATE STYLONYCHIA-LEMNAE - SPECIAL CODON USAGE - TAA IS NOT A TRANSLATION TERMINATION CODON	32	150
347	26	34	1939 1996 INTERNATIONAL JOURNAL OF ONCOLOGY 9 (3): 453-458 Hiyama E; Tatsumoto N; Kodama T; Hiyama K; Shay JW; et al. Telomerase activity in human intestine	102	150
348	31	58	2249 1997 GENES & DEVELOPMENT 11 (6): 748-760 Wotton D; Shore D Novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae	112	150
349	10	16	356 1986 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 51: 213-219 COOKE HJ; SMITH BA VARIABILITY AT THE TELOMERES OF THE HUMAN X/Y PSEUDOAUTOSOMAL REGION	124	149
350	19	28	641 1988 NATURE 332 (6165): 656-659 ALLSHIRE RC; GOSDEN JR; CROSS SH; CRANSTON G; ROUT D; et al. TELOMERIC REPEAT FROM T-THERMOPHILA CROSS HYBRIDIZES WITH HUMAN TELOMERES	127	149
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
351	4	20	1097 1992 CELL 68 (2): 333-339 FERGUSON BM; FANGMAN WL A POSITION EFFECT ON THE TIME OF REPLICATION ORIGIN ACTIVATION IN YEAST	36	149
352	22	55	1527 1994 MOLECULAR AND CELLULAR BIOLOGY 14 (2): 961-969 KLINGELHUTZ AJ; BARBER SA; SMITH PP; DYER K; MCDOUGALL JK RESTORATION OF TELOMERES IN HUMAN PAPILLOMAVIRUS-IMMORTALIZED HUMAN ANOGENITAL EPITHELIAL-CELLS	101	149
353	10	35	1779 1995 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92 (1): 258-262 KRUK PA; RAMPINO NJ; BOHR VA DNA-DAMAGE AND REPAIR IN TELOMERES - RELATION TO AGING	78	149
354	15	29	2158 1997 CANCER 79 (2): 362-369 Yoshida K; Sugino T; Tahara H; Woodman A; Bolodeoku J; et al. Telomerase activity in bladder carcinoma and its implication for noninvasive diagnosis by detection of exfoliated cancer cells in urine	73	149
355	3	34	1798 1995 SCIENCE 270 (5238): 994-997 HYRIEN O; MARIC C; MECHALI M TRANSITION IN SPECIFICATION OF EMBRYONIC METAZOAN DNA-REPLICATION ORIGINS	5	148
356	7	67	232 1984 JOURNAL OF MOLECULAR BIOLOGY 180 (4): 1023-1051 HUDSON GS; DAVIDSON BE NUCLEOTIDE-SEQUENCE AND TRANSCRIPTION OF THE PHENYLALANINE AND TYROSINE OPERONS OF ESCHERICHIA-COLI-K12	7	147
357	18	29	1083 1992 BIOCHEMISTRY 31 (35): 8112-8119 WANG Y; PATEL DJ GUANINE RESIDUES IN D(T2AG3) AND D(T2G4) FORM PARALLEL-STRANDED POTASSIUM CATION STABILIZED G-QUADRUPLEXES WITH ANTIGLYCOSIDIC TORSION ANGLES IN SOLUTION	87	147
358	23	65	1341 1993 JOURNAL OF MOLECULAR BIOLOGY 231 (2): 293-310 GILSON E; ROBERGE M; GIRALDO R; RHODES D; GASSER SM DISTORTION OF THE DNA DOUBLE HELIX BY RAP1 AT SILENCERS AND MULTIPLE TELOMERIC BINDING-SITES	79	147
359	22	32	2065 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93 (24): 13760-13765 Lin JJ; Zakian VA The Saccharomyces CDC13 protein is a single-strand TG(1-3) telomeric DNA-binding protein in vitro that affects telomere behavior in vivo	123	147
360	47	85	2975 1999 CELL 99 (7): 723-733 Diede SJ; Gottschling DE Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta	107	147
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
361	5	96	778 1989 SCIENCE 246 (4930): 609-614 LASKEY RA; FAIRMAN MP; BLOW JJ S-PHASE OF THE CELL-CYCLE	2	146
362	10	30	1334 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268 (24): 17651-17654 PADMANABHAN K; PADMANABHAN KP; FERRARA JD; SADLER JE; TULINSKY A THE STRUCTURE OF ALPHA-THROMBIN INHIBITED BY A 15-MER SINGLE-STRANDED-DNA APTAMER	35	146
363	31	49	2418 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (25): 13677-13682 Belair CD; Yeager TR; Lopez PM; Reznikoff CA Telomerase activity: A biomarker of cell proliferation, not malignant transformation	80	146
364	18	35	2967 1999 CANCER RESEARCH 59 (23): 5917-5921 Kyo S; Takakura M; Kanaya T; Zhuo W; Fujimoto K; et al. Estrogen activates telomerase	70	146
365	13	21	654 1988 NUCLEIC ACIDS RESEARCH 16 (14): 6953-6972 ZAHLER AM; PRESCOTT DM TELOMERE TERMINAL TRANSFERASE-ACTIVITY IN THE HYPOTRICHOUS CILIATE OXYTRICHA-NOVA AND A MODEL FOR REPLICATION OF THE ENDS OF LINEAR DNA-MOLECULES	138	145
366	3	87	961 1991 EXPERIMENTAL CELL RESEARCH 192 (2): 325-332 HAAF T; SCHMID M CHROMOSOME TOPOLOGY IN MAMMALIAN INTERPHASE NUCLEI	9	145
367	14	35	3645 2000 NATURE MEDICINE 6 (8): 849-851 Wright WE; Shay JW Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology	68	145
368	28	31	1034 1991 NATURE 353 (6343): 454-456 MORIN GB RECOGNITION OF A CHROMOSOME TRUNCATION SITE ASSOCIATED WITH ALPHA-THALASSEMIA BY HUMAN TELOMERASE	119	144
369	154	211	5169 2004 ANNUAL REVIEW OF BIOCHEMISTRY 73: 177-208 Smogorzewska A; de Lange T Regulation of telomerase by telomeric proteins	96	144
370	3	31	1623 1995 CELL 82 (4): 545-554 ZIMMERLY S; GUO HT; PERLMAN PS; LAMBOWITZ AM GROUP-II INTRON MOBILITY OCCURS BY TARGET DNA-PRIMED REVERSE TRANSCRIPTION	11	143
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
371	13	18	2714 1998 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 120 (13): 3261-3262 Wheelhouse RT; Sun DK; Han HY; Han FXG; Hurley LH Cationic porphyrins as telomerase inhibitors: the interaction of tetra- (N-methyl-4-pyridyl)porphine with quadruplex DNA	85	143
372	35	46	3019 1999 EMBO JOURNAL 18 (11): 2950-2960 Herrera E; Samper E; Martin-Caballero J; Flores JM; Lee HW; et al. Disease states associated with telomerase deficiency appear earlier in mice with short telomeres	102	143
373	17	97	4626 2002 SCIENCE 297 (5581): 552-557 Kolodner RD; Putnam CD; Myung K Maintenance of genome stability in Saccharomyces cerevisiae	16	143
374	4	76	606 1988 JOURNAL OF HEREDITY 79 (6): 409-417 EPPLEN JT ON SIMPLE REPEATED GA-C-T-A SEQUENCES IN ANIMAL GENOMES - A CRITICAL REAPPRAISAL	0	142
375	2	34	697 1989 EMBO JOURNAL 8 (2): 483-488 ESSER C; RADBRUCH A RAPID INDUCTION OF TRANSCRIPTION OF UNREARRANGED S-GAMMA-1 SWITCH REGIONS IN ACTIVATED MURINE B-CELLS BY INTERLEUKIN-4	1	142
376	22	37	750 1989 NATURE 337 (6206): 429-433 PLUTA AF; ZAKIAN VA RECOMBINATION OCCURS DURING TELOMERE FORMATION IN YEAST	120	142
377	3	34	1053 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88 (1): 26-30 LI Y; ZON G; WILSON WD NMR AND MOLECULAR MODELING EVIDENCE FOR A G.A MISMATCH BASE PAIR IN A PURINE-RICH DNA DUPLEX	9	142
378	4	147	1077 1992 ANNUAL REVIEW OF CELL BIOLOGY 8: 275-306 WHITCOMB JM; HUGHES SH RETROVIRAL REVERSE TRANSCRIPTION AND INTEGRATION - PROGRESS AND PROBLEMS	1	142
379	18	64	1869 1996 CELL 85 (1): 125-136 Konig P; Giraldo R; Chapman L; Rhodes D The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA	77	141
380	25	69	1929 1996 IMMUNITY 5 (3): 207-216 Morrison SJ; Prowse KR; Ho P; Weissman IL Telomerase activity in hematopoietic cells is associated with self-renewal potential	54	141
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
381	32	65	2001 1996 MOLECULAR BIOLOGY OF THE CELL 7 (9): 1443-1454 Buchkovich KJ; Greider CW Telomerase regulation during entry into the cell cycle in normal human T cells	102	141
382	29	41	2412 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (17): 9202-9207 Counter CM; Meyerson M; Eaton EN; Weinberg RA The catalytic subunit of yeast telomerase	113	141
383	3	34	3256 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (6): 2902-2906 Myler PJ; Audleman L; DeVos T; Hixson G; Kiser P; et al. Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes	11	141
384	9	13	3409 2000 CURRENT BIOLOGY 10 (20): 1299-1302 Smith S; de Lange T Tankyrase promotes telomere elongation in human cells	85	141
385	20	49	4637 2002 TRENDS IN BIOCHEMICAL SCIENCES 27 (7): 339-344 von Zglinicki T Oxidative stress shortens telomeres	67	141
386	6	64	267 1985 CELL 42 (1): 173-182 CULLY DF; IP HS; CROSS GAM COORDINATE TRANSCRIPTION OF VARIANT SURFACE GLYCOPROTEIN GENES AND AN EXPRESSION SITE ASSOCIATED GENE FAMILY IN TRYPANOSOMA BRUCEI	11	140
387	3	42	292 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260 (10): 6334-6340 SPANGLER EA; BLACKBURN EH THE NUCLEOTIDE-SEQUENCE OF THE 17-S RIBOSOMAL-RNA GENE OF TETRAHYMENA-THERMOPHILA AND THE IDENTIFICATION OF POINT MUTATIONS RESULTING IN RESISTANCE TO THE ANTIBIOTICS PAROMOMYCIN AND HYGROMYCIN	140	140
388	4	290	1236 1993 ADVANCES IN CANCER RESEARCH 60: 121-156 CHENG KC; LOEB LA GENOMIC INSTABILITY AND TUMOR PROGRESSION - MECHANISTIC CONSIDERATIONS	9	140
389	46	58	801 1990 BIOESSAYS 12 (8): 363-369 GREIDER CW TELOMERES, TELOMERASE AND SENESCENCE	81	139
390	3	22	1003 1991 JOURNAL OF MOLECULAR EVOLUTION 33 (1): 83-91 SACCONE C; PESOLE G; SBISA E THE MAIN REGULATORY REGION OF MAMMALIAN MITOCHONDRIAL-DNA - STRUCTURE-FUNCTION MODEL AND EVOLUTIONARY PATTERN	2	139
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
391	6	54	1180 1992 MOLECULAR AND CELLULAR BIOLOGY 12 (6): 2749-2757 HENDERSON ST; PETES TD INSTABILITY OF SIMPLE SEQUENCE DNA IN SACCHAROMYCES-CEREVISIAE	4	139
392	15	20	2541 1998 CELL 92 (5): 587-590 Nakamura TM; Cech TR Reversing time: Origin of telomerase	100	139
393	46	62	3110 1999 JOURNAL OF CELL BIOLOGY 144 (4): 589-601 Hande MP; Samper E; Lansdorp P; Blasco MA Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice	102	138
394	7	44	564 1988 CELL 55 (5): 869-874 POLOGE LG; RAVETCH JV LARGE DELETIONS RESULT FROM BREAKAGE AND HEALING OF P-FALCIPARUM CHROMOSOMES	45	137
395	3	159	789 1990 ANNUAL REVIEW OF GENETICS 24: 409-445 KATZ RA; SKALKA AM GENERATION OF DIVERSITY IN RETROVIRUSES	2	137
396	4	37	1042 1991 NUCLEIC ACIDS RESEARCH 19 (9): 2349-2357 MARQUET R; BAUDIN F; GABUS C; DARLIX JL; MOUGEL M; et al. DIMERIZATION OF HUMAN-IMMUNODEFICIENCY-VIRUS (TYPE-1) RNA - STIMULATION BY CATIONS AND POSSIBLE MECHANISM	8	137
397	3	30	1744 1995 NATURE 375 (6532): 611-614 CUENOUD B; SZOSTAK JW A DNA METALLOENZYME WITH DNA-LIGASE ACTIVITY	1	137
398	10	84	2802 1998 ONCOGENE 16 (9): 1113-1123 Robles SJ; Adami GR Agents that cause DNA double strand breaks lead to p16(INK4a) enrichment and the premature senescence of normal fibrolasts	36	137
399	17	113	1595 1995 ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY 11: 519-548 Loo S; Rine J Silencing and heritable domains of gene expression	6	136
400	16	28	3455 2000 FREE RADICAL BIOLOGY AND MEDICINE 28 (1): 64-74 Von Zglinicki T; Pilger R; Sitte N Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts	60	136

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