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#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1301	28	70	810 1990 CELL 63 (4): 739-750 CONRAD MN; WRIGHT JH; WOLF AJ; ZAKIAN VA RAP1 PROTEIN INTERACTS WITH YEAST TELOMERES INVIVO - OVERPRODUCTION ALTERS TELOMERE STRUCTURE AND DECREASES CHROMOSOME STABILITY	205	284
1302	25	71	811 1990 CELL 63 (4): 751-762 GOTTSCHLING DE; APARICIO OM; BILLINGTON BL; ZAKIAN VA POSITION EFFECT AT SACCHAROMYCES-CEREVISIAE TELOMERES - REVERSIBLE REPRESSION OF POL-II TRANSCRIPTION	208	692
1303	26	39	812 1990 CELL 63 (4): 763-772 YAO MC; YAO CH; MONKS B THE CONTROLLING SEQUENCE FOR SITE-SPECIFIC CHROMOSOME BREAKAGE IN TETRAHYMENA	68	77
1304	11	71	941 1991 CELL 66 (6): 1279-1287 APARICIO OM; BILLINGTON BL; GOTTSCHLING DE MODIFIERS OF POSITION EFFECT ARE SHARED BETWEEN TELOMERIC AND SILENT MATING-TYPE LOCI IN SACCHAROMYCES-CEREVISIAE	72	397
1305	18	65	942 1991 CELL 67 (2): 343-353 ROMERO DP; BLACKBURN EH A CONSERVED SECONDARY STRUCTURE FOR TELOMERASE RNA	159	159
1306	21	42	943 1991 CELL 67 (3): 505-516 YASUDA LF; YAO MC SHORT INVERTED REPEATS AT A FREE END SIGNAL LARGE PALINDROMIC DNA FORMATION IN TETRAHYMENA	18	35
1307	13	20	944 1991 CELL 67 (4): 645-647 GREIDER CW CHROMOSOME 1ST AID	37	54
1308	26	47	945 1991 CELL 67 (4): 807-814 GRAY JT; CELANDER DW; PRICE CM; CECH TR CLONING AND EXPRESSION OF GENES FOR THE OXYTRICHA TELOMERE-BINDING PROTEIN - SPECIFIC SUBUNIT INTERACTIONS IN THE TELOMERIC COMPLEX	91	114
1309	9	24	946 1991 CELL 67 (4): 815-822 MULLER F; WICKY C; SPICHER A; TOBLER H NEW TELOMERE FORMATION AFTER DEVELOPMENTALLY REGULATED CHROMOSOMAL BREAKAGE DURING THE PROCESS OF CHROMATIN DIMINUTION IN ASCARIS-LUMBRICOIDES	57	80
1310	36	45	947 1991 CELL 67 (4): 823-832 YU GL; BLACKBURN EH DEVELOPMENTALLY PROGRAMMED HEALING OF CHROMOSOMES BY TELOMERASE IN TETRAHYMENA	160	160
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1311	1	14	948 1991 CELL 67 (6): 1041-1046 FRANKEL AD; MATTAJ IW; RIO DC RNA-PROTEIN INTERACTIONS	1	55
1312	4	20	1097 1992 CELL 68 (2): 333-339 FERGUSON BM; FANGMAN WL A POSITION EFFECT ON THE TIME OF REPLICATION ORIGIN ACTIVATION IN YEAST	36	149
1313	27	56	1271 1993 CELL 72 (1): 51-60 WELLINGER RJ; WOLF AJ; ZAKIAN VA SACCHAROMYCES TELOMERES ACQUIRE SINGLE-STRAND TG(1-3) TAILS LATE IN S-PHASE	175	208
1314	3	27	1272 1993 CELL 72 (2): 161-164 WEINER AM MESSENGER-RNA SPLICING AND AUTOCATALYTIC INTRONS - DISTANT COUSINS OR THE PRODUCTS OF CHEMICAL DETERMINISM	2	90
1315	7	36	1273 1993 CELL 72 (3): 397-406 LU Y; HALL T; GAY LS; DONELSON JE POINT MUTATIONS ARE ASSOCIATED WITH A GENE DUPLICATION LEADING TO THE BLOOD-STREAM REEXPRESSION OF A TRYPANOSOME METACYCLIC VSG	2	42
1316	40	51	1274 1993 CELL 73 (2): 347-360 LUNDBLAD V; BLACKBURN EH AN ALTERNATIVE PATHWAY FOR YEAST TELOMERE MAINTENANCE RESCUES EST1-SENESCENCE	436	435
1317	29	71	1275 1993 CELL 73 (4): 775-787 MAKAROV VL; LEJNINE S; BEDOYAN J; LANGMORE JP NUCLEOSOMAL ORGANIZATION OF TELOMERE-SPECIFIC CHROMATIN IN RAT	65	84
1318	30	53	1276 1993 CELL 74 (5): 875-885 FANG GW; CECH TR THE BETA-SUBUNIT OF OXYTRICHA TELOMERE-BINDING PROTEIN PROMOTES G-QUARTET FORMATION BY TELOMERIC DNA	130	178
1319	18	50	1277 1993 CELL 75 (3): 543-555 PALLADINO F; LAROCHE T; GILSON E; AXELROD A; PILLUS L; et al. SIR3 AND SIR4 PROTEINS ARE REQUIRED FOR THE POSITIONING AND INTEGRITY OF YEAST TELOMERES	78	231
1320	7	45	1278 1993 CELL 75 (6): 1071-1081 WANG H; LAMBOWITZ AM THE MAURICEVILLE PLASMID REVERSE-TRANSCRIPTASE CAN INITIATE CDNA SYNTHESIS DE-NOVO AND MAY BE RELATED TO REVERSE-TRANSCRIPTASE AND DNA-POLYMERASE PROGENITOR	14	67
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1321	28	86	1279 1993 CELL 75 (6): 1083-1093 LEVIS RW; GANESAN R; HOUTCHENS K; TOLAR LA; SHEEN FM TRANSPOSONS IN-PLACE OF TELOMERIC REPEATS AT A DROSOPHILA TELOMERE	127	235
1322	24	57	1425 1994 CELL 76 (1): 145-155 SCHULZ VP; ZAKIAN VA THE SACCHAROMYCES PIF1 DNA HELICASE INHIBITS TELOMERE ELONGATION AND DE-NOVO TELOMERE FORMATION	52	93
1323	12	21	1426 1994 CELL 77 (5): 621-623 BLACKBURN EH TELOMERES - NO END IN SIGHT	201	200
1324	15	36	1427 1994 CELL 77 (7): 1083-1092 LIU ZP; GILBERT W THE YEAST KEM1 GENE ENCODES A NUCLEASE SPECIFIC FOR G4 TETRAPLEX DNA - IMPLICATION OF IN-VIVO FUNCTIONS FAR THIS NOVEL DNA-STRUCTURE	46	112
1325	21	37	1621 1995 CELL 81 (5): 677-686 COLLINS K; KOBAYASHI R; GREIDER CW PURIFICATION OF TETRAHYMENA TELOMERASE AND CLONING OF GENES ENCODING THE 2 PROTEIN-COMPONENTS OF THE ENZYME	192	221
1326	38	52	1622 1995 CELL 81 (7): 1127-1135 LIN JJ; ZAKIAN VA AN IN-VITRO ASSAY FOR SACCHAROMYCES TELOMERASE REQUIRES EST1	65	73
1327	3	31	1623 1995 CELL 82 (4): 545-554 ZIMMERLY S; GUO HT; PERLMAN PS; LAMBOWITZ AM GROUP-II INTRON MOBILITY OCCURS BY TARGET DNA-PRIMED REVERSE TRANSCRIPTION	11	143
1328	9	46	1624 1995 CELL 82 (5): 823-829 GREENWELL PW; KRONMAL SL; PORTER SE; GASSENHUBER J; OBERMAIER B; et al. TEL1, A GENE INVOLVED IN CONTROLLING TELOMERE LENGTH IN SACCHAROMYCES-CEREVISIAE, IS HOMOLOGOUS TO THE HUMAN ATAXIA-TELANGIECTASIA GENE	102	261
1329	10	45	1868 1996 CELL 84 (4): 633-642 Smeal T; Claus J; Kennedy B; Cole F; Guarente L Loss of transcriptional silencing causes sterility in old mother cells of S-cerevisiae	14	97
1330	18	64	1869 1996 CELL 85 (1): 125-136 Konig P; Giraldo R; Chapman L; Rhodes D The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA	77	141
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1331	35	73	1870 1996 CELL 85 (3): 423-433 Wellinger RJ; Ethier K; Labrecque P; Zakian VA Evidence for a new step in telomere maintenance	141	176
1332	29	33	1871 1996 CELL 87 (3): 369-375 Lundblad V; Wright WE Telomeres and telomerase: A simple picture becomes complex	48	74
1333	33	54	2177 1997 CELL 88 (5): 657-666 Makarov VL; Hirose Y; Langmore JP Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening	230	292
1334	34	47	2178 1997 CELL 88 (6): 875-884 Nakayama JI; Saito M; Nakamura H; Matsuura A; Ishikawa F TLP1: A gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family	226	326
1335	41	65	2179 1997 CELL 90 (4): 785-795 Meyerson M; Counter CM; Eaton EN; Ellisen LW; Steiner P; et al. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization	586	976
1336	14	18	2180 1997 CELL 91 (1): 1-3 Zakian VA Life and cancer without telomerase	22	33
1337	31	53	2181 1997 CELL 91 (1): 25-34 Blasco MA; Lee HW; Hande MP; Samper E; Lansdorp PM; et al. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA	538	795
1338	34	51	2540 1998 CELL 92 (3): 401-413 van Steensel B; Smogorzewska A; de Lange T TRF2 protects human telomeres from end-to-end fusions	436	589
1339	15	20	2541 1998 CELL 92 (5): 587-590 Nakamura TM; Cech TR Reversing time: Origin of telomerase	100	139
1340	30	54	2542 1998 CELL 95 (7): 963-974 Horvath MP; Schweiker VL; Bevilacqua JM; Ruggles JA; Schultz SC Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA	75	123
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1341	29	66	2969 1999 CELL 96 (5): 701-712 Rudolph KL; Chang S; Lee HW; Blasco M; Gottlieb GJ; et al. Longevity, stress response, and cancer in aging telomerase-deficient mice	225	400
1342	6	64	2970 1999 CELL 97 (1): 99-109 Wei Y; Yu LL; Bowen J; Gorovsky MA; Allis CD Phosphorylation of histone H3 is required for proper chromosome condensation and segregation	4	253
1343	14	20	2971 1999 CELL 97 (4): 419-422 Greider CW Telomeres do d-loop-t-loop	59	76
1344	29	52	2972 1999 CELL 97 (4): 503-514 Griffith JD; Comeau L; Rosenfield S; Stansel RM; Bianchi A; et al. Mammalian telomeres end in a large duplex loop	527	705
1345	27	57	2973 1999 CELL 97 (4): 515-525 Greenberg RA; Chin L; Femino A; Lee KH; Gottlieb GJ; et al. Short dysfunctional telomeres impair tumorigenesis in the INK4a(Delta 2/3) cancer-prone mouse	113	179
1346	17	44	2974 1999 CELL 97 (4): 527-538 Chin L; Artandi SE; Shen Q; Tam A; Lee SL; et al. p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis	212	348
1347	47	85	2975 1999 CELL 99 (7): 723-733 Diede SJ; Gottschling DE Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta	107	147
1348	9	102	3379 2000 CELL 100 (1): 57-70 Hanahan D; Weinberg RA The hallmarks of cancer	92	3136
1349	39	67	3380 2000 CELL 100 (5): 503-514 Chen JL; Blasco MA; Greider CW Secondary structure of vertebrate telomerase RNA	147	188
1350	43	75	3381 2000 CELL 101 (5): 471-483 Li BB; Oestreich S; de Lange T Identification of human Rap1: Implications for telomere evolution	128	169
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1351	6	20	3382 2000 CELL 102 (4): 407-410 Sherr CJ; DePinho RA Cellular senescence: Mitotic clock or culture shock?	72	259
1352	3	63	3383 2000 CELL 103 (7): 1143-1154 Brodersen DE; Clemons WM; Carter AP; Morgan-Warren RJ; Wimberly BT; et al. The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit	4	164
1353	28	34	3798 2001 CELL 104 (3): 387-396 Pennock E; Buckley K; Lundblad V Cdc13 delivers separate complexes to the telomere for end protection and replication	107	120
1354	22	48	3799 2001 CELL 106 (3): 275-286 Hackett JA; Feldser DM; Greider CW Telomere dysfunction increases mutation rate and genomic instability	85	109
1355	81	108	3800 2001 CELL 106 (6): 661-673 Blackburn EH Switching and signaling at the telomere	429	429
1356	31	50	3801 2001 CELL 107 (1): 67-77 Hemann MT; Strong MA; Hao LY; Greider CW The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability	160	217
1357	41	71	3802 2001 CELL 107 (3): 347-359 Zhou XZ; Lu KP The Pin2/TRF1-interacting: Protein PinX1 is a potent telomerase inhibitor	66	93
1358	8	54	4250 2002 CELL 111 (3): 433-444 Kajikawa M; Okada N LINEs mobilize SINEs in the eel through a shared 3 ' sequence	4	72
1359	27	43	4762 2003 CELL 113 (5): 565-576 Karamysheva Z; Wang LB; Shrode T; Bednenko J; Hurley LA; et al. Developmentally programmed gene elimination in Euplotes crassus facilitates a switch in the telomerase catalytic subunit	6	12
1360	32	68	4763 2003 CELL 113 (7): 881-889 Lin SY; Elledge SJ Multiple tumor suppressor pathways negatively regulate telomerase	41	103
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1361	42	60	4764 2003 CELL 114 (2): 241-253 Masutomi K; Yu EY; Khurts S; Ben-Porath I; Currier JL; et al. Telomerase maintains telomere structure in normal human cells	144	206
1362	59	73	5247 2004 CELL 116 (2): 273-279 Cech TR Beginning to understand the end of the chromosome	38	69
1363	64	77	5248 2004 CELL 117 (3): 323-335 Teixeira MT; Arneric M; Sperisen P; Lingner J Telomere length homeostasis is achieved via a switch between telomerase-extendible and -nonextendible states	65	69
1364	37	64	5249 2004 CELL 117 (3): 337-347 Tarsounas M; Munoz P; Claas A; Smiraldo PG; Pittman DL; et al. Telomere maintenance requires the RAD51D recombination/repair protein	28	49
1365	33	54	5250 2004 CELL 117 (7): 873-886 Ding H; Schertzer M; Wu XL; Gertsenstein M; Selig S; et al. Regulation of murine telomere length by Rtel: An essential gene encoding a helicase-like protein	14	22
1366	6	85	5251 2004 CELL 118 (6): 699-713 Lisby M; Barlow JH; Burgess RC; Rothstein R Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins	8	100
1367	38	72	5252 2004 CELL 119 (3): 355-368 Wang RC; Smogorzewska A; de Lange T Homologous recombination generates T-loop-sized deletions at human telomeres	44	63
1368	6	93	5795 2005 CELL 120 (4): 557-567 Hadley EC; Lakatta EG; Morrison-Bogorad M; Warner HR; Hodes RJ The future of aging therapies	0	11
1369	35	49	5796 2005 CELL 123 (6): 1121-1131 Hao LY; Armanios M; Strong MA; Karim B; Feldser DM; et al. Short telomeres, even in the presence of telomerase, limit tissue renewal capacity	3	3
1370	36	60	6297 2006 CELL 124 (6): 1155-1168 Downey M; Houlsworth R; Maringele L; Rollie A; Brehme M; et al. A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator	2	4
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1371	6	49	6298 2006 CELL 125 (7): 1283-1296 Narayanan V; Mieczkowski PA; Kim HM; Petes TD; Lobachev KS The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks	0	1
1372	34	63	6299 2006 CELL 126 (1): 49-62 Wu L; Multani AS; He H; Cosme-Blanco W; Deng Y; et al. Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres	0	2
1373	7	21	5253 2004 CELL AND TISSUE RESEARCH 315 (3): 331-337 Sawa Y; Yamaoka Y; Kuroshima S; Yoshida S Reduction of alkaline phosphatase activity in aged human osteogenic periodontal ligament fibroblasts exhibiting short telomeres	0	0
1374	14	38	5797 2005 CELL AND TISSUE RESEARCH 319 (3): 405-412 Garcia-Escarp M; Martinez-Munoz V; Barquinero J; Sales-Pardo I; Domingo JC; et al. A rare fraction of human hematopoietic stem cells with large telomeres	1	1
1375	16	22	3803 2001 CELL BIOCHEMISTRY AND FUNCTION 19 (1): 65-68 Fukutomi M; Enjoji M; Iguchi H; Yokota M; Iwamoto H; et al. Telomerase activity is repressed during differentiation along the hepatocytic and biliary epithelial lineages: verification on immortal cell lines from the same origin	0	3
1376	1	15	3804 2001 CELL BIOLOGY AND TOXICOLOGY 17 (4): 213-230 Freshney I Application of cell cultures to toxicology	0	1
1377	12	27	4251 2002 CELL BIOLOGY INTERNATIONAL 26 (12): 1019-1027 Yegorov YE; Kazimirchuk EV; Terekhov SM; Karachentsev DN; Shirokova EA; et al. Telomerase-dependent reactivation of DNA synthesis in macrophages implies alteration of telomeres	0	0
1378	18	133	5798 2005 CELL BIOLOGY INTERNATIONAL 29 (12): 1084-1097 Rajaraman R; Rajaraman MM; Rajaraman SR; Guernsey DL Neosis - a paradigm of self-renewal in cancer	0	2
1379	8	11	5254 2004 CELL CYCLE 3 (5): 547-549 Bechter OE; Shay JW; Wright WE The frequency of homologous recombination in human ALT cells	5	6
1380	18	43	5255 2004 CELL CYCLE 3 (6): 811-816 Freedman DA; Folkman J Maintenance of G(1) checkpoint controls in telomerase-immortalized endothelial cells	3	5
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1381	110	194	5256 2004 CELL CYCLE 3 (9): 1138-1150 Satyanarayana A; Manns MP; Rudolph KL Telomeres, telomerase and cancer - An endless search to target the ends	1	4
1382	23	39	5257 2004 CELL CYCLE 3 (9): 1169-1176 Jeyapalan J; Leake A; Ahmed S; Saretzki G; Tilby M; et al. The role of telomeres in etoposide induced tumor cell death	3	4
1383	20	49	5258 2004 CELL CYCLE 3 (10): 1217-1220 Gire V Dysfunctional telomeres at senescence signal cell cycle arrest via Chk2	0	1
1384	36	47	5799 2005 CELL CYCLE 4 (4): 585-589 Cerone MA; Ward RJ; Londono-Vallejo JA; Autexier C Telomerase RNA mutated in autosomal dyskeratosis congenita reconstitutes a weakly active telomerase enzyme defective in telomere elongation	5	5
1385	16	27	5800 2005 CELL CYCLE 4 (5): 672-674 Tarsounas M; West SC Recombination at mammalian telomeres - An alternative mechanism for telomere protection and elongation	0	0
1386	19	36	5801 2005 CELL CYCLE 4 (6): 747-751 Maringele L; Lydall D The PAL-mechanism of chromosome maintenance - Causes and consequences	1	1
1387	7	35	5802 2005 CELL CYCLE 4 (8): 1007-1010 Gisselsson D Mitotic instability in cancer - Is there method in the madness?	0	1
1388	12	19	5803 2005 CELL CYCLE 4 (10): 1320-1322 Wang YS; Giannone RJ; Liu Y Telomere sister chromatid exchange in telomerase deficient murine cells	1	1
1389	24	91	6300 2006 CELL CYCLE 5 (6): 630-634 Heeg S; Doebele M; von Werder A; Opitz OG In vitro transformation models - Modeling human cancer	0	0
1390	9	19	6301 2006 CELL CYCLE 5 (7): 718-721 Munoz P; Blanco R; Blasco MA Role of the TRF2 telomeric protein in cancer and ageing	0	0
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1391	19	62	6302 2006 CELL CYCLE 5 (9): 930-935 Alonso MM; Fueyo J; Yung WKA; Gomez-Manzano C E2F1 and telomerase - Alliance in the dark side	0	0
1392	23	34	6303 2006 CELL CYCLE 5 (13): 1403-1406 Nishiyama A; Ishikawa F Cell-cycle-dependent regulation of telomere binding proteins - Roles of Polo-like kinase	0	0
1393	9	199	3805 2001 CELL DEATH AND DIFFERENTIATION 8 (11): 1052-1065 Khanna KK; Lavin MF; Jackson SP; Mulhern TD ATM, a central controller of cellular responses to DNA damage	4	64
1394	26	52	5804 2005 CELL DEATH AND DIFFERENTIATION 12 (11): 1429-1438 Del Bufalo D; Rizzo A; Trisciuoglio D; Cardinali G; Torrisi MR; et al. Involvement of hTERT in apoptosis induced by interference with Bcl-2 expression and function	2	3
1395	4	51	355 1986 CELL DIFFERENTIATION 18 (4): 243-256 GUTIERREZ JC; ORIAS E DEVELOPMENTAL AND GENETIC-EFFECTS OF ALCIAN BLUE IN CONJUGATING TETRAHYMENA-THERMOPHILA - DOUBLET FORMATION AND MACRONUCLEAR RETENTION	0	0
1396	1	45	565 1988 CELL DIFFERENTIATION 23 (1-2): 27-36 BARETTINO D; MORCILLO G; DIEZ JL INDUCTION OF THE HEAT-SHOCK RESPONSE BY CARBON-DIOXIDE IN CHIRONOMUS-THUMMI	0	15
1397	29	50	2543 1998 CELL GROWTH & DIFFERENTIATION 9 (1): 85-95 Kang MK; Guo WT; Park NH Replicative senescence of normal human oral keratinocytes is associated with the loss of telomerase activity without shortening of telomeres	19	45
1398	22	58	3806 2001 CELL GROWTH & DIFFERENTIATION 12 (2): 119-127 Yang H; Kyo S; Takatura M; Sun LZ Autocrine transforming growth factor beta suppresses telomerase activity and transcription of human telomerase reverse transcriptase in human cancer cells	11	29
1399	9	61	3807 2001 CELL GROWTH & DIFFERENTIATION 12 (10): 487-496 Pritchard DE; Ceryak S; Ha L; Fornsaglio JL; Hartman SK; et al. Mechanism of apoptosis and determination of cellular fate in chromium(VI)-exposed populations of telomerase-immortalized human fibroblasts	2	19
1400	29	80	3808 2001 CELL GROWTH & DIFFERENTIATION 12 (11): 525-534 Goodwin EC; DiMaio D Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres	5	24

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