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#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
301	24	142	5090 2003 PATHOLOGIE BIOLOGIE 51 (10): 550-562 Macieira-Coelho A From Weismann's theory to present day gerontology 1889-2003	0	0
302	90	142	5319 2004 DEVELOPMENTAL BIOLOGY 274 (1): 15-30 Bekaert S; Derradji H; Baatout S Telomere biology in mammalian germ cells and during development	6	8
303	58	142	6322 2006 CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 59 (1): 1-14 Jefford CE; Irminger-Finger I Mechanisms of chromosome instability in cancers	0	1
304	9	141	2196 1997 CLINICAL NEUROLOGY AND NEUROSURGERY 99 (3): 184-195 Santarius T; Kirsch M; Rossi ML; Black PM Molecular aspects of neuro-oncology	0	9
305	90	141	4573 2002 ONCOGENE 21 (4): 564-579 Collins K; Mitchell JR Telomerase in the human organism	90	129
306	94	141	6201 2005 REPRODUCTION FERTILITY AND DEVELOPMENT 17 (1-2): 85-96 Schaetzlein S; Rudolph KL Telomere length regulation during cloning, embryogenesis and ageing	2	4
307	8	140	732 1989 MICROBIOLOGICAL REVIEWS 53 (3): 299-317 VOLKERT FC; WILSON DW; BROACH JR DEOXYRIBONUCLEIC-ACID PLASMIDS IN YEASTS	1	52
308	2	140	4416 2002 JOURNAL OF CELLULAR PHYSIOLOGY 190 (1): 7-20 Ravid K; Lu J; Zimmet JM; Jones MR Roads to polyploidy: The megakaryocyte example	1	49
309	1	140	5289 2004 CURRENT DRUG TARGETS 5 (8): 667-681 Schubert S; Kurreck J Ribozyme-and deoxyribozyme-strategies for medical applications	1	7
310	5	139	703 1989 EXPERIMENTAL CELL RESEARCH 185 (2): 297-318 HILLIKER AJ; APPELS R THE ARRANGEMENT OF INTERPHASE CHROMOSOMES - STRUCTURAL AND FUNCTIONAL-ASPECTS	11	66
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
311	9	139	2183 1997 CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE 60 (4): 172-184 Santarius T; Kirsch M; Black PM Current topics in molecular biology of brain tumors	0	1
312	39	139	2876 1999 ACTA PROTOZOOLOGICA 38 (3): 215-248 Foissner W; Berger H Identification and ontogenesis of the nomen nudum Hypotrichs (Protozoa : Ciliophora) Oxytricha nova (= Sterkiella nova sp n.) and O. trifallax (= S. histriomuscorum)	0	18
313	64	139	3344 2000 BIOPOLYMERS 56 (3): 123-146 Keniry MA Quadruplex structures in nucleic acids	9	30
314	90	139	3637 2000 MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH 462 (1): 31-47 Cerni C Telomeres, telomerase, and myc. An update	23	46
315	2	138	966 1991 GENE 100: 13-26 SZYBALSKI W; KIM SC; HASAN N; PODHAJSKA AJ CLASS-IIS RESTRICTION ENZYMES - A REVIEW	0	123
316	103	138	5314 2004 CYTOTECHNOLOGY 45 (1-2): 75-90 Guittat L; Alberti P; Gomez D; De Cian A; Pennarun G; et al. Targeting human telomerase for cancer therapeutics	2	3
317	12	137	4009 2001 JOURNAL OF UROLOGY 165 (2): 600-611 Konety BR; Getzenberg RH Urine based markers of urological malignancy	2	46
318	21	137	4696 2003 BIOCHEMISTRY-MOSCOW 68 (1): 2-33 Olovnikov AM The redusome hypothesis of aging and the control of biological time during individual development	1	2
319	90	137	6245 2006 ANNUAL REVIEW OF BIOCHEMISTRY 75: 111-135 McEachern MJ; Haber JE Break-induced replication and recombinational telomere elongation in yeast	0	1
320	5	137	6438 2006 MEDICAL HYPOTHESES 66 (3): 612-635 Wynter CVA The dialectics of cancer: A theory of the initiation and development of cancer through errors in RNAi	0	0
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
321	12	136	4520 2002 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 509 (1-2): 35-47 Wu L; Hickson ID RecQ helicases and cellular responses to DNA damage	2	26
322	6	135	1086 1992 BIOCHEMISTRY 31 (47): 11665-11676 TENDAM E; PLEIJ K; DRAPER D STRUCTURAL AND FUNCTIONAL-ASPECTS OF RNA PSEUDOKNOTS	7	83
323	85	135	4237 2002 CANCER INVESTIGATION 20 (1): 82-101 Helder MN; Wisman GBA; van der Zee AGJ Telomerase and telomeres: From basic biology to cancer treatment	11	20
324	7	135	4929 2003 JOURNAL OF BIOSCIENCES 28 (3): 337-348 Chakrabarti O; Krishna S Molecular interactions of 'high risk' human papillomaviruses E6 and E7 oncoproteins: implications for tumour progression	1	5
325	14	134	91 1979 CRC CRITICAL REVIEWS IN BIOCHEMISTRY 6 (1): 1-33 AIR GM RAPID DNA-SEQUENCE ANALYSIS	0	3
326	5	134	102 1980 ANNUAL REVIEW OF GENETICS 14: 203-239 GOROVSKY MA GENOME ORGANIZATION AND REORGANIZATION IN TETRAHYMENA	68	129
327	13	134	1707 1995 JOURNAL OF INDUSTRIAL MICROBIOLOGY 14 (5): 355-364 LEMKE PA INDUSTRIAL MYCOLOGY AND THE NEW GENETICS	0	1
328	11	134	5062 2003 NUCLEIC ACIDS RESEARCH 31 (10): 2461-2474 Chou SH; Chin KH; Wang AHJ Unusual DNA duplex and hairpin motifs	1	17
329	3	134	6547 2006 TOXICOLOGY MECHANISMS AND METHODS 16 (2-3): 137-159 Choudhuri S Some major landmarks in the path from nuclein to human genome	0	1
330	3	133	1454 1994 EUROPEAN JOURNAL OF HISTOCHEMISTRY 38 (2): 91-109 SUMNER AT FUNCTIONAL-ASPECTS OF THE LONGITUDINAL DIFFERENTIATION OF CHROMOSOMES	0	15
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331	75	133	4394 2002 INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 218 218: 37-67 Zalenskaya IA; Zalensky AO Telomeres in mammalian male germline cells	4	6
332	60	133	4698 2003 BIOCHEMISTRY-MOSCOW 68 (7): 718-734 Dmitriev PV; Petrov AV; Dontsova OA Yeast telosome complex: Components and their functions	1	1
333	15	133	5774 2005 CANCER JOURNAL 11 (4): 294-305 Wang LL Biology of osteogenic sarcoma	0	0
334	18	133	5798 2005 CELL BIOLOGY INTERNATIONAL 29 (12): 1084-1097 Rajaraman R; Rajaraman MM; Rajaraman SR; Guernsey DL Neosis - a paradigm of self-renewal in cancer	0	2
335	9	132	3788 2001 BRITISH JOURNAL OF HAEMATOLOGY 113 (1): 11-23 Holyoake TL Recent advances in the molecular and cellular biology of chronic myeloid leukaemia: Lessons to be learned from the laboratory	0	11
336	85	132	5837 2005 CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 54 (2): 85-93 Dong CK; Masutomi K; Hahn WC Telomerase: regulation, function and transformation	7	9
337	1	132	5914 2005 FRONTIERS IN BIOSCIENCE 10: 728-742 Emdad L; Sarkar D; Su ZZ; Fisher PB Emerging roles of centrosomal amplification and genomic instability in cancer	0	5
338	28	131	4758 2003 CARCINOGENESIS 24 (5): 791-802 Opresko PL; Cheng WH; von Kobbe C; Harrigan JA; Bohr VA Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process	7	51
339	6	131	5827 2005 CHRONIC LYMPHOCYTIC LEUKEMIA 294: 109-133 Chiorazzi N; Allen SL; Ferrarini M Clinical and laboratory parameters that define clinically relevant B-CLL subgroups	0	0
340	56	131	6551 2006 UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS 24 (2): 122-130 Meeker AK Telomeres and telomerase in prostatic intraepithelial neoplasia and prostate cancer biology	0	0
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
341	53	130	4537 2002 NATURE REVIEWS GENETICS 3 (2): 91-102 Mefford HC; Trask BJ The complex structure and dynamic evolution of human subtelomeres	23	87
342	20	130	5938 2005 GENOME INSTABILITY IN CANCER DEVELOPMENT 570: 175-197 Jeggo PA Genomic instability in cancer development	0	0
343	9	128	1060 1991 PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY 40: 143-184 SIMPSON RT NUCLEOSOME POSITIONING - OCCURRENCE, MECHANISMS, AND FUNCTIONAL CONSEQUENCES	4	191
344	85	128	2527 1998 CANCER JOURNAL 4: S26-S34 Shay JW Telomerase in cancer: Diagnostic, prognostic, and therapeutic implications	16	25
345	84	128	5042 2003 MOLECULES AND CELLS 15 (2): 164-175 Djojosubroto MW; Choi YS; Lee HW; Rudolph KL Telomeres and telomerase in aging, regeneration and cancer	17	26
346	13	128	6251 2006 ASIAN JOURNAL OF ANDROLOGY 8 (2): 131-142 Emery BR; Carrell DT The effect of epigenetic sperm abnormalities on early embryo-genesis	0	0
347	26	127	383 1986 INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY 99: 49-83 BRUNK CF GENOME REORGANIZATION IN TETRAHYMENA	38	43
348	9	127	665 1988 PROCESS BIOCHEMISTRY 23 (2): 36-42 ESSER K; KAMPER J TRANSFORMATION SYSTEMS IN YEASTS - FUNDAMENTALS AND APPLICATIONS IN BIOTECHNOLOGY	0	4
349	1	127	2349 1997 MEDICAL HYPOTHESES 49 (4): 337-345 Fischer KM Parkinson's disease, amyotrophic lateral sclerosis and spinal muscular atrophy are caused by an unstable (CAG)(n) trinucleotide repeat microsatellite	0	1
350	5	127	5196 2004 BIODRUGS 18 (6): 387-398 Bogen SA; Sompuram SR Recent trends and advances in immunodiagnostics of solid tumors	0	1
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
351	74	127	5961 2005 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 37 (5): 1000-1013 Gilley D; Tanaka H; Herbert BS Telomere dysfunction in aging and cancer	4	5
352	63	126	5960 2005 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 37 (5): 977-990 Rodier F; Kim SH; Nijjar T; Yaswen P; Campisi J Cancer and aging: the importance of telomeres in genome maintenance	3	10
353	55	126	6085 2005 MOLECULAR AND CELLULAR ENDOCRINOLOGY 240 (1-2): 11-22 Bayne S; Liu JP Hormones and growth factors regulate telomerase activity in ageing and cancer	2	3
354	12	125	141 1982 CELL NUCLEUS 11: 193-223 VAVRA KJ; COLAVITOSHEPANSKI M; GOROVSKY MA ORGANIZATION OF RDNA IN CHROMATIN - TETRAHYMENA	1	1
355	8	125	328 1985 PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY 32: 1-26 PAYS E GENE CONVERSION IN TRYPANOSOME ANTIGENIC VARIATION	4	29
356	10	125	384 1986 INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY 99: 85-117 DELANGE T THE MOLECULAR-BIOLOGY OF ANTIGENIC VARIATION IN TRYPANOSOMES - GENE REARRANGEMENTS AND DISCONTINUOUS TRANSCRIPTION	3	10
357	6	125	2846 1998 STEM CELLS 16 (3): 153-165 Mayani H; Lansdorp PM Biology of human umbilical cord blood-derived hematopoietic stem/progenitor cells	3	75
358	88	125	3716 2000 VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY 437 (1): 1-16 Dhaene K; Van Marck E; Parwaresch R Telomeres, telomerase and cancer: an up-date	30	67
359	26	125	4375 2002 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 34 (11): 1401-1414 Krtolica A; Campisi J Cancer and aging: a model for the cancer promoting effects of the aging stroma	5	33
360	16	125	4434 2002 JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS 7 (1): 51-58 Yaar M; Eller MS; Gilchrest BA Fifty years of skin aging	0	6
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361	32	125	5152 2004 AGING CELL 3 (6): 333-343 Miura T; Mattson MP; Rao MS Cellular lifespan and senescence signaling in embryonic stem cells	1	9
362	8	125	5579 2004 NATURE REVIEWS MOLECULAR CELL BIOLOGY 5 (1): 45-54 Storchova Z; Pellman D From polyploidy to aneuploidy, genome instability and cancer	4	76
363	22	125	5581 2004 NATURE REVIEWS MOLECULAR CELL BIOLOGY 5 (5): 367-378 Downs JA; Jackson SP A means to a DNA end: The many roles of Ku	10	36
364	80	125	5844 2005 CURRENT MOLECULAR MEDICINE 5 (2): 135-143 Crabbe L; Karlseder J In the end, it's all structure	1	1
365	1	125	6214 2005 STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS 8 (1): 69-83 Bauer ME Stress, glucocorticoids and ageing of the immune system	0	0
366	3	124	48 1977 ANNUAL REPORTS ON THE PROGRESS OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY 74: 432-446 SUMMERS MC; WILLIAMS DC BIOLOGICAL CHEMISTRY .4. ENZYME CHEMISTRY	0	1
367	9	124	3764 2001 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1552 (1): 27-37 Tong WM; Cortes U; Wang ZQ Poly(ADP-ribose) polymerase: a guardian angel protecting the genome and suppressing tumorigenesis	2	52
368	78	124	4652 2003 ADVANCES IN CANCER RESEARCH, VOL 87 87: 31-58 Chen Z; Corey DR Telomerase inhibitors: A new option for chemotherapy	6	9
369	15	124	5171 2004 ANNUAL REVIEW OF GENETICS 38: 273-304 Tower J Developmental gene amplification and origin regulation	0	8
370	13	124	5707 2005 ANNUAL REVIEW OF MICROBIOLOGY 59: 135-153 Liti G; Louis EJ Yeast evolution and comparative genomics	1	6
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371	56	124	5850 2005 CURRENT MOLECULAR MEDICINE 5 (2): 197-203 von Zglinicki T; Martin-Ruiz CM Telomeres as biomarkers for ageing and age-related diseases	1	1
372	29	124	5915 2005 FRONTIERS IN BIOSCIENCE 10: 940-950 Freedman DA Senescence and its bypass in the vascular endothelium	2	3
373	9	124	6031 2005 JOURNAL OF PATHOLOGY 205 (2): 181-193 Maddison K; Clarke AR New approaches for modelling cancer mechanisms in the mouse	0	4
374	53	124	6419 2006 JOURNAL OF MOLECULAR BIOLOGY 359 (5): 1217-1234 Buczek P; Horvath MP Thermodynamic characterization of binding Oxytricha nova single strand telomere DNA with the alpha protein N-terminal domain	1	1
375	21	123	206 1984 ANNUAL REVIEW OF BIOCHEMISTRY 53: 163-194 BLACKBURN EH; SZOSTAK JW THE MOLECULAR-STRUCTURE OF CENTROMERES AND TELOMERES	502	502
376	23	123	4432 2002 JOURNAL OF INVESTIGATIVE DERMATOLOGY 118 (5): 752-758 Chang E; Yang JW; Nagavarapu U; Herron GS Aging and survival of cutaneous microvasculature	1	12
377	18	123	4542 2002 NEW ENGLAND JOURNAL OF MEDICINE 347 (20): 1593-1603 Hahn WC; Weinberg RA Mechanisms of disease: Rules for making human tumor cells.	4	157
378	79	123	4830 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270 (3): 389-403 Saldanha SN; Andrews LG; Tollefsbol TO Assessment of telomere length and factors that contribute to its stability	10	17
379	50	123	5469 2004 JOURNAL OF CLINICAL INVESTIGATION 113 (2): 160-168 Sharpless NE; DePinho RA Telomeres, stem cells, senescence, and cancer	22	84
380	2	123	6399 2006 JOURNAL OF BEHAVIORAL MEDICINE 29 (4): 389-400 Graham JE; Christian LM; Kiecolt-Glaser JK Stress, age, and immune function: Toward a lifespan approach	0	0
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381	5	122	192 1983 NATURE 305 (5933): 391-397 STRUHL K THE NEW YEAST GENETICS	7	165
382	12	122	1146 1992 GENOME 35 (2): 171-181 LAPITAN NLV ORGANIZATION AND EVOLUTION OF HIGHER-PLANT NUCLEAR GENOMES	7	81
383	46	122	6373 2006 GENETICS 173 (1): 401-417 Kuo HF; Olsen KM; Richards EJ Natural variation in a subtelomeric region of arabidopsis: Implications for the genomic dynamics of a chromosome end	0	0
384	7	121	2703 1998 JOURNAL OF MOLECULAR EVOLUTION 46 (1): 1-17 Poole AM; Jeffares DC; Penny D The path from the RNA world	3	52
385	10	121	3399 2000 CLINICAL CHEMISTRY 46 (5): 595-605 Burchardt M; Burchardt T; Shabsigh A; De la Taille A; Benson MC; et al. Current concepts in biomarker technology for bladder cancers	1	44
386	86	121	3676 2000 ONCOGENE 19 (56): 6632-6641 Bearss DJ; Hurley LH; Von Hoff DD Telomere maintenance mechanisms as a target for drug development	19	38
387	2	121	5208 2004 BIOPOLYMERS 73 (1): 79-89 Hsieh J; Andrews AJ; Fierke CA Roles of protein subunits in RNA-protein complexes: Lessons from ribonuclease P	0	17
388	28	121	5409 2004 HUMAN BIOLOGY 76 (1): 127-146 Demerath EW; Cameron N; Gillman MW; Towne B; Siervogel RM Telomeres and telomerase in the fetal origins of cardiovascular disease: A review	0	5
389	69	121	5824 2005 CHROMOSOME RESEARCH 13 (5): 535-548 Teixeira MT; Gilson E Telomere maintenance, function and evolution: the yeast paradigm	1	1
390	46	121	5853 2005 CURRENT MOLECULAR MEDICINE 5 (2): 219-226 Opitz OG Telomeres, telomerase and malignant transformation	1	3
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391	12	121	6174 2005 PLOS GENETICS 1 (6): 634-650 Budd ME; Tong AHY; Polaczek P; Peng X; Boone C; et al. A network of multi-tasking proteins at the DNA replication fork preserves genome stability	0	1
392	83	120	1865 1996 CANCER SURVEYS 28: 197-216 Bacchetti S Telomere maintenance in tumour cells	17	30
393	66	120	3878 2001 EXPERIMENTAL GERONTOLOGY 36 (10): 1619-1637 Campisi J; Kim SH; Lim CS; Rubio M Cellular senescence, cancer and aging: the telomere connection	38	74
394	8	120	4037 2001 MOLECULAR AND CELLULAR BIOLOGY 21 (9): 3144-3158 Hanna JS; Kroll ES; Lundblad V; Spencer FA Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion	3	78
395	5	120	4301 2002 ENDOCRINOLOGIST 12 (2) Bauer AJ; Tuttle RM; Francis GL Differentiated thyroid carcinoma of children and adolescents	0	4
396	13	120	4886 2003 HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA 17 (4): 927-+ Nicosia SV; Bai WL; Cheng JQ; Coppola D; Kruk PA Oncogenic pathways implicated in ovarian epithelial cancer	0	12
397	65	120	5820 2005 CHROMOSOME RESEARCH 13 (5): 481-491 Gallego ME; White CI DNA repair and recombination functions in Arabidopsis telomere maintenance	0	0
398	11	119	261 1985 BIOCHIMICA ET BIOPHYSICA ACTA 824 (1): 1-15 BERNARDS A ANTIGENIC VARIATION OF TRYPANOSOMES	1	10
399	1	119	465 1987 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 52: 709-719 GERBI SA; JEPPESEN C; STEBBINSBOAZ B; ARES M EVOLUTION OF EUKARYOTIC RIBOSOMAL-RNA - CONSTRAINTS IMPOSED BY RNA INTERACTIONS	0	14
400	1	118	345 1986 BIOSYSTEMS 19 (4): 247-258 GERBI SA THE EVOLUTION OF EUKARYOTIC RIBOSOMAL DNA	0	38

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