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#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
401	18	33	2047 1996 ONCOGENE 13 (10): 2265-2274 Tatematsu K; Nakayama J; Danbara M; Shionoya S; Sato H; et al. A novel quantitative 'stretch PCR assay', that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias	61	97
402	49	71	3020 1999 EMBO JOURNAL 18 (12): 3509-3519 Marcand S; Brevet V; Gilson E Progressive cis-inhibition of telomerase upon telomere elongation	61	65
403	32	61	3173 1999 MOLECULAR AND CELLULAR BIOLOGY 19 (3): 1864-1870 Halvorsen TL; Leibowitz G; Levine F Telomerase activity is sufficient to allow transformed cells to escape from crisis	61	92
404	16	16	3408 2000 CURRENT BIOLOGY 10 (13): 809-812 Hughes TR; Evans SK; Weilbaecher RG; Lundblad V The Est3 protein is a subunit of yeast telomerase	61	63
405	15	20	4149 2001 SCIENCE 293 (5539): 2462-2465 Bailey SM; Cornforth MN; Kurimasa A; Chen DJ; Goodwin EH Strand-specific postreplicative processing of mammalian telomeres	61	83
406	12	27	5659 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (49): 17312-17315 Epel ES; Blackburn EH; Lin J; Dhabhar FS; Adler NE; et al. Accelerated telomere shortening in response to life stress	61	61
407	15	37	138 1982 CELL 31 (1): 177-182 KING BO; YAO MC TANDEMLY REPEATED HEXANUCLEOTIDE AT TETRAHYMENA RDNA FREE END IS GENERATED FROM A SINGLE COPY DURING DEVELOPMENT	60	67
408	6	10	1078 1992 BIOCHEMISTRY 31 (1): 65-70 SEN D; GILBERT W NOVEL DNA SUPERSTRUCTURES FORMED BY TELOMERE-LIKE OLIGOMERS	60	119
409	25	37	1260 1993 BIOCHEMISTRY 32 (43): 11646-11657 FANG GW; CECH TR CHARACTERIZATION OF A G-QUARTET FORMATION REACTION PROMOTED BY THE BETA-SUBUNIT OF THE OXYTRICHA TELOMERE-BINDING PROTEIN	60	91
410	41	66	1894 1996 EMBO JOURNAL 15 (7): 1734-1741 Wright WE; Brasiskyte D; Piatyszek MA; Shay JW Experimental elongation of telomeres extends the lifespan of immortal x normal cell hybrids	60	98
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
411	21	35	2228 1997 EUROPEAN JOURNAL OF CANCER 33 (5): 781-786 Kim NW Clinical implications of telomerase in cancer	60	107
412	20	38	2832 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (20): 11549-11554 Pitts AE; Corey DR Inhibition of human telomerase by 2 '-O-methyl-RNA	60	86
413	16	28	3455 2000 FREE RADICAL BIOLOGY AND MEDICINE 28 (1): 64-74 Von Zglinicki T; Pilger R; Sitte N Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts	60	136
414	19	23	4795 2003 CURRENT BIOLOGY 13 (11): 942-946 Colgin LM; Baran K; Baumann P; Cech TR; Reddel RR Human POT1 facilitates telomere elongation by telomerase	60	70
415	15	22	237 1984 MOLECULAR AND CELLULAR BIOLOGY 4 (11): 2509-2517 HOROWITZ H; THORBURN P; HABER JE REARRANGEMENTS OF HIGHLY POLYMORPHIC REGIONS NEAR TELOMERES OF SACCHAROMYCES-CEREVISIAE	59	79
416	19	46	575 1988 EMBO JOURNAL 7 (4): 1081-1086 BIESSMANN H; MASON JM PROGRESSIVE LOSS OF DNA-SEQUENCES FROM TERMINAL CHROMOSOME DEFICIENCES IN DROSOPHILA-MELANOGASTER	59	86
417	9	26	908 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87 (3): 867-870 PANYUTIN IG; KOVALSKY OI; BUDOWSKY EI; DICKERSON RE; RIKHIREV ME; et al. G-DNA - A TWICE-FOLDED DNA-STRUCTURE ADOPTED BY SINGLE-STRANDED OLIGO(DG) AND ITS IMPLICATIONS FOR TELOMERES	59	92
418	15	27	1251 1993 BIOCHEMISTRY 32 (8): 1899-1904 WANG KY; MCCURDY S; SHEA RG; SWAMINATHAN S; BOLTON PH A DNA APTAMER WHICH BINDS TO AND INHIBITS THROMBIN EXHIBITS A NEW STRUCTURAL MOTIF FOR DNA	59	174
419	28	46	2314 1997 JOURNAL OF CLINICAL PATHOLOGY 50 (2): 110-117 Yashima K; Piatyszek MA; Saboorian HM; Virmani AK; Brown D; et al. Telomerase activity and in situ telomerase RNA expression in malignant and non-malignant lymph nodes	59	83
420	14	20	2971 1999 CELL 97 (4): 419-422 Greider CW Telomeres do d-loop-t-loop	59	76
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
421	22	31	3626 2000 MOLECULAR CELL 6 (2): 361-371 Mitchell JR; Collins K Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase	59	73
422	43	52	3650 2000 NATURE STRUCTURAL BIOLOGY 7 (10): 847-850 Blackburn EH The end of the (DNA) line	59	59
423	16	36	1051 1991 PLANT CELL 3 (1): 87-94 GANAL MW; LAPITAN NLV; TANKSLEY SD MACROSTRUCTURE OF THE TOMATO TELOMERES	58	98
424	30	37	1572 1994 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91 (8): 3453-3457 MCEACHERN MJ; BLACKBURN EH A CONSERVED SEQUENCE MOTIF WITHIN THE EXCEPTIONALLY DIVERSE TELOMERIC SEQUENCES OF BUDDING YEASTS	58	58
425	37	50	2210 1997 EMBO JOURNAL 16 (4): 866-879 Wang H; Blackburn EH De nova telomere addition by Tetrahymena telomerase in vitro	58	58
426	11	13	2775 1998 NATURE MEDICINE 4 (12): 1366-1367 Mergny JL; Helene C G-quadruplex DNA: A target for drug design	58	121
427	13	38	2806 1998 ONCOGENE 16 (17): 2243-2248 Kondo Y; Kondo S; Tanaka Y; Haqqi T; Barna BP; et al. Inhibition of telomerase increases the susceptibility of human malignant glioblastoma cells to cisplatin-induced apoptosis	58	100
428	17	54	523 1987 MOLECULAR AND CELLULAR BIOLOGY 7 (1): 435-443 AUSTERBERRY CF; YAO MC NUCLEOTIDE-SEQUENCE STRUCTURE AND CONSISTENCY OF A DEVELOPMENTALLY REGULATED DNA DELETION IN TETRAHYMENA-THERMOPHILA	57	65
429	9	24	946 1991 CELL 67 (4): 815-822 MULLER F; WICKY C; SPICHER A; TOBLER H NEW TELOMERE FORMATION AFTER DEVELOPMENTALLY REGULATED CHROMOSOMAL BREAKAGE DURING THE PROCESS OF CHROMATIN DIMINUTION IN ASCARIS-LUMBRICOIDES	57	80
430	45	52	1666 1995 GENES & DEVELOPMENT 9 (18): 2227-2239 AUTEXIER C; GREIDER CW BOUNDARY ELEMENTS OF THE TETRAHYMENA TELOMERASE RNA TEMPLATE AND ALIGNMENT DOMAINS	57	57
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
431	36	55	1997 1996 MOLECULAR AND CELLULAR BIOLOGY 16 (7): 3437-3445 Melek M; Greene EC; Skippen DE Processing of nontelomeric 3' ends by telomerase: Default template alignment and endonucleolytic cleavage	57	59
432	13	27	2220 1997 EUROPEAN JOURNAL OF CANCER 33 (4): 638-644 Burger AM; Double JA; Newell DR Inhibition of telomerase activity by cisplatin in human testicular cancer cells	57	94
433	28	79	2221 1997 EUROPEAN JOURNAL OF CANCER 33 (5): 703-709 Campisi J The biology of replicative senescence	57	197
434	36	44	2354 1997 MOLECULAR AND CELLULAR BIOLOGY 17 (1): 296-308 Hammond PW; Lively TN; Cech TR The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single-and double-stranded DNA primers	57	62
435	29	44	2447 1997 TRENDS IN GENETICS 13 (1): 21-26 Smith S; deLange T TRF1, a mammalian telomeric protein	57	81
436	27	40	3054 1999 GENES & DEVELOPMENT 13 (21): 2863-2874 Friedman KL; Cech TR Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants	57	64
437	26	27	3410 2000 CURRENT BIOLOGY 10 (22): 1459-1462 Liu Y; Snow BE; Hande MP; Yeung D; Erdmann NJ; et al. The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo	57	72
438	8	26	3469 2000 GENETICS 155 (1): 475-479 Ritchie KB; Petes TD The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast	57	81
439	46	50	3851 2001 EMBO JOURNAL 20 (13): 3526-3534 Wenz C; Enenkel B; Amacker M; Kelleher C; Damm K; et al. Human telomerase contains two cooperating telomerase RNA molecules	57	60
440	57	80	4536 2002 NATURE REVIEWS DRUG DISCOVERY 1 (5): 383-393 Neidle S; Parkinson G Telomere maintenance as a target for anticancer drug discovery	57	109
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
441	4	31	115 1981 CELL 24 (3): 765-774 YAO MC RIBOSOMAL-RNA GENE AMPLIFICATION IN TETRAHYMENA MAY BE ASSOCIATED WITH CHROMOSOME BREAKAGE AND DNA ELIMINATION	56	70
442	7	33	135 1982 CELL 28 (3): 595-604 PAN WC; ORIAS E; FLACKS M; BLACKBURN EH ALLELE-SPECIFIC, SELECTIVE AMPLIFICATION OF A RIBOSOMAL-RNA GENE IN TETRAHYMENA THERMOPHILA	56	56
443	2	12	187 1983 NATURE 302 (5903): 84-86 WALMSLEY RM; SZOSTAK JW; PETES TD IS THERE LEFT-HANDED DNA AT THE ENDS OF YEAST CHROMOSOMES	56	88
444	21	35	635 1988 MOLECULAR AND CELLULAR BIOLOGY 8 (11): 4642-4650 MURRAY AW; CLAUS TE; SZOSTAK JW CHARACTERIZATION OF 2 TELOMERIC DNA PROCESSING REACTIONS IN SACCHAROMYCES-CEREVISIAE	56	65
445	34	58	1488 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269 (34): 21858-21869 BALAGURUMOORTHY P; BRAHMACHARI SK STRUCTURE AND STABILITY OF HUMAN TELOMERIC SEQUENCE	56	118
446	26	35	2538 1998 CANCER RESEARCH 58 (23): 5406-5410 Yokoyama Y; Takahashi Y; Shinohara A; Lian ZL; Wan XY; et al. Attenuation of telomerase activity by a hammerhead ribozyme targeting the template region of telomerase RNA in endometrial carcinoma cells	56	76
447	19	33	2601 1998 EXPERIMENTAL CELL RESEARCH 239 (1): 152-160 Petersen S; Saretzki G; von Zglinicki T Preferential accumulation of single-stranded regions in telomeres of human fibroblasts	56	102
448	42	50	3611 2000 MOLECULAR AND CELLULAR BIOLOGY 20 (14): 5196-5207 Xia JQ; Peng Y; Mian IS; Lue NF Identification of functionally important domains in the N-terminal region of telomerase reverse transcriptase	56	67
449	4	44	127 1981 MOLECULAR AND CELLULAR BIOLOGY 1 (6): 535-543 KISS GB; AMIN AA; PEARLMAN RE 2 SEPARATE REGIONS OF THE EXTRACHROMOSOMAL RIBOSOMAL DEOXYRIBONUCLEIC-ACID OF TETRAHYMENA-THERMOPHILA ENABLE AUTONOMOUS REPLICATION OF PLASMIDS IN SACCHAROMYCES-CEREVISIAE	55	94
450	49	59	1311 1993 GENES & DEVELOPMENT 7 (5): 883-894 CARDENAS ME; BIANCHI A; DELANGE T A XENOPUS EGG FACTOR WITH DNA-BINDING PROPERTIES CHARACTERISTIC OF TERMINUS-SPECIFIC TELOMERIC PROTEINS	55	57
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
451	21	27	1715 1995 JOURNAL OF THE NATIONAL CANCER INSTITUTE 87 (12): 859-861 MORIN GB IS TELOMERASE A UNIVERSAL CANCER TARGET	55	66
452	27	46	1756 1995 NUCLEIC ACIDS RESEARCH 23 (7): 1091-1097 MCCORMICKGRAHAM M; ROMERO DP CILIATE TELOMERASE RNA STRUCTURAL FEATURES	55	58
453	54	88	1888 1996 CURRENT OPINION IN BIOTECHNOLOGY 7 (6): 583-591 Raymond E; Sun D; Chen SF; Windle B; VonHoff DD Agents that target telomerase and telomeres	55	73
454	30	75	1952 1996 JOURNAL OF CELL BIOLOGY 135 (4): 867-881 Luderus ME; vanSteensel B; Chong L; Sibon OCM; Cremers FFM; et al. Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex	55	107
455	29	49	2339 1997 JOURNAL OF THE NATIONAL CANCER INSTITUTE 89 (24): 1874-1881 Clark GM; Osborne CK; Levitt D; Wu F; Kim NW Telomerase activity and survival of patients with node-positive breast cancer	55	94
456	24	49	3827 2001 CURRENT BIOLOGY 11 (17): 1328-1335 Tsukamoto Y; Taggart AKP; Zakian VA The role of the Mre11-Rad50-Xrs2 complex in telomerase-mediated lengthening of Saccharomyces cerevisiae telomeres	55	73
457	35	44	3892 2001 GENES & DEVELOPMENT 15 (4): 404-414 Chandra A; Hughes TR; Nugent CI; Lundblad V Cdc13 both positively and negatively regulates telomere replication	55	62
458	48	64	4043 2001 MOLECULAR AND CELLULAR BIOLOGY 21 (18): 6151-6160 Beattie TL; Zhou W; Robinson MO; Harrington L Functional multimerization of the human telomerase reverse transcriptase	55	62
459	27	48	5034 2003 MOLECULAR CELL 11 (5): 1379-1387 Chan SWL; Blackburn EH Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining	55	55
460	1	23	3 1972 JOURNAL OF BIOLOGICAL CHEMISTRY 247 (14): 4441-& DAVIDSON BE; Blackburn EH; DOPHEIDE TA CHORISMATE MUTASE-PREPHENATE DEHYDRATASE FROM ESCHERICHIA-COLI K-12 .1. PURIFICATION, MOLECULAR-WEIGHT, AND AMINO-ACID COMPOSITION	54	54
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
461	11	33	280 1985 EMBO JOURNAL 4 (3): 799-804 SAIGA H; EDSTROM JE LONG TANDEM ARRAYS OF COMPLEX REPEAT UNITS IN CHIRONOMUS TELOMERES	54	70
462	13	42	309 1985 MOLECULAR AND CELLULAR BIOLOGY 5 (8): 2039-2050 HOWARD EA; BLACKBURN EH REPRODUCIBLE AND VARIABLE GENOMIC REARRANGEMENTS OCCUR IN THE DEVELOPING SOMATIC NUCLEUS OF THE CILIATE TETRAHYMENA-THERMOPHILA	54	54
463	15	39	322 1985 NUCLEIC ACIDS RESEARCH 13 (16): 5817-5831 ALTSCHULER MI; YAO MC MACRONUCLEAR DNA OF TETRAHYMENA-THERMOPHILA EXISTS AS DEFINED SUB-CHROMOSOMAL-SIZED MOLECULES	54	63
464	9	49	540 1987 SCIENCE 236 (4803): 806-812 BURKE DT; CARLE GF; OLSON MV CLONING OF LARGE SEGMENTS OF EXOGENOUS DNA INTO YEAST BY MEANS OF ARTIFICIAL CHROMOSOME VECTORS	54	1208
465	7	7	1095 1992 CANCER GENETICS AND CYTOGENETICS 61 (2): 204-206 ADAMSON DJA; KING DJ; HAITES NE SIGNIFICANT TELOMERE SHORTENING IN CHILDHOOD LEUKEMIA	54	68
466	23	49	1223 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89 (18): 8832-8836 JIN RZ; GAFFNEY BL; WANG C; JONES RA; BRESLAUER KJ THERMODYNAMICS AND STRUCTURE OF A DNA TETRAPLEX - A SPECTROSCOPIC AND CALORIMETRIC STUDY OF THE TETRAMOLECULAR COMPLEXES OF D(TG3T) AND D(TG3T2G3T)	54	106
467	38	63	1469 1994 GENETICS 136 (3): 789-802 LOUIS EJ; NAUMOVA ES; LEE A; NAUMOV G; HABER JE THE CHROMOSOME END IN YEAST - ITS MOSAIC NATURE AND INFLUENCE ON RECOMBINATIONAL DYNAMICS	54	125
468	12	21	1827 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 225 (2): 570-576 Kanazawa Y; Ohkawa K; Ueda K; Mita E; Takehara T; et al. Hammerhead ribozyme-mediated inhibition of telomerase activity in extracts of human hepatocellular carcinoma cells	54	75
469	11	19	1906 1996 FEBS LETTERS 389 (2): 115-118 Yegorov YE; Chernov DN; Akimov SS; Bolsheva NL; Krayevsky AA; et al. Reverse transcriptase inhibitors suppress telomerase function and induce senescence-like processes in cultured mouse fibroblasts	54	62
470	25	69	1929 1996 IMMUNITY 5 (3): 207-216 Morrison SJ; Prowse KR; Ho P; Weissman IL Telomerase activity in hematopoietic cells is associated with self-renewal potential	54	141
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
471	12	19	2118 1997 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 241 (3): 730-736 Ku WC; Cheng AJ; Wang TCV Inhibition of telomerase activity by PKC inhibitors in human nasopharyngeal cancer cells in culture	54	100
472	27	39	2419 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (25): 13782-13785 Notaro R; Cimmino A; Tabarini D; Rotoli B; Luzzatto L In vivo telomere dynamics of human hematopoietic stem cells	54	110
473	12	27	3209 1999 NATURE 401 (6749): 177-180 Seto AG; Zaug AJ; Sobel SG; Wolin SL; Cech TR Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle	54	99
474	25	63	3846 2001 EMBO JOURNAL 20 (4): 905-913 Johnson FB; Marciniak RA; McVey M; Stewart SA; Hahn WC; et al. The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase	54	96
475	25	31	874 1990 MOLECULAR AND CELLULAR BIOLOGY 10 (8): 4415-4419 WANG SS; ZAKIAN VA SEQUENCING OF SACCHAROMYCES TELOMERES CLONED USING T4-DNA POLYMERASE REVEALS 2 DOMAINS	53	57
476	59	83	1638 1995 CURRENT OPINION IN STRUCTURAL BIOLOGY 5 (3): 311-322 RHODES D; GIRALDO R TELOMERE STRUCTURE AND FUNCTION	53	99
477	36	50	2626 1998 GENES & DEVELOPMENT 12 (20): 3286-3300 Roy J; Fulton TB; Blackburn EH Specific telomerase RNA residues distant from the template are essential for telomerase function	53	53
478	16	21	2657 1998 INTERNATIONAL JOURNAL OF CANCER 79 (1): 8-12 Hoos A; Hepp HH; Kaul S; Ahlert T; Bastert G; et al. Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer	53	79
479	74	104	3114 1999 JOURNAL OF CELLULAR PHYSIOLOGY 180 (1): 10-18 Holt SE; Shay JW Role of telomerase in cellular proliferation and cancer	53	118
480	40	62	3265 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (26): 14813-14818 Fitzgerald MS; Riha K; Gao F; Ren SX; McKnight TD; et al. Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA	53	67
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
481	5	32	3453 2000 FEBS LETTERS 481 (1): 81-85 Song K; Jung D; Jung Y; Lee SG; Lee I Interaction of human Ku70 with TRF2	53	68
482	33	48	3826 2001 CURRENT BIOLOGY 11 (16): 1240-1250 Chan SWL; Chang J; Prescott J; Blackburn EH Altering telomere structure allows telomerase to act in yeast lacking ATM kinases	53	53
483	5	18	202 1983 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 80 (11): 3406-3410 DANI GM; ZAKIAN VA MITOTIC AND MEIOTIC STABILITY OF LINEAR PLASMIDS IN YEAST	52	102
484	3	52	638 1988 MOLECULAR AND CELLULAR BIOLOGY 8 (12): 5086-5099 BUCHMAN AR; LUE NF; KORNBERG RD CONNECTIONS BETWEEN TRANSCRIPTIONAL ACTIVATORS, SILENCERS, AND TELOMERES AS REVEALED BY FUNCTIONAL-ANALYSIS OF A YEAST DNA-BINDING PROTEIN	52	234
485	19	52	1079 1992 BIOCHEMISTRY 31 (3): 833-841 HARDIN CC; WATSON T; CORREGAN M; BAILEY C CATION-DEPENDENT TRANSITION BETWEEN THE QUADRUPLEX AND WATSON-CRICK HAIRPIN FORMS OF D(CGCG3GCG)	52	99
486	9	24	1154 1992 JAPANESE JOURNAL OF CANCER RESEARCH 83 (2): 159-164 HIYAMA E; HIYAMA K; YOKOYAMA T; ICHIKAWA T; MATSUURA Y LENGTH OF TELOMERIC REPEATS IN NEUROBLASTOMA - CORRELATION WITH PROGNOSIS AND OTHER BIOLOGICAL CHARACTERISTICS	52	76
487	12	52	1384 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90 (8): 3393-3397 SUNDQUIST WI; HEAPHY S EVIDENCE FOR INTERSTRAND QUADRUPLEX FORMATION IN THE DIMERIZATION OF HUMAN IMMUNODEFICIENCY VIRUS-1 GENOMIC RNA	52	161
488	24	57	1425 1994 CELL 76 (1): 145-155 SCHULZ VP; ZAKIAN VA THE SACCHAROMYCES PIF1 DNA HELICASE INHIBITS TELOMERE ELONGATION AND DE-NOVO TELOMERE FORMATION	52	93
489	27	42	1836 1996 BIOCHEMISTRY 35 (49): 15611-15617 Fletcher TM; Salazar M; Chen SF Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates	52	57
490	20	42	2167 1997 CANCER RESEARCH 57 (2): 326-331 Hiyama E; Kodama T; Shinbara K; Iwao T; Itoh M; et al. Telomerase activity is detected in pancreatic cancer but not in benign tumors	52	125
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
491	15	25	2280 1997 HUMAN PATHOLOGY 28 (4): 416-420 Langford LA; Piatyszek MA; Xu RS; Schold SC; Wright WE; et al. Telomerase activity in ordinary meningiomas predicts poor outcome	52	89
492	5	30	2553 1998 CLINICAL CANCER RESEARCH 4 (3): 693-696 Melana SM; Holland JF; Pogo BGT Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3 '-azido-3 '-deoxythymidine	52	68
493	31	41	2693 1998 JOURNAL OF MEDICINAL CHEMISTRY 41 (17): 3253-3260 Perry PJ; Gowan SM; Reszka AP; Polucci P; Jenkins TC; et al. 1,4-and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase	52	86
494	16	30	2695 1998 JOURNAL OF MOLECULAR BIOLOGY 278 (1): 79-88 Griffith J; Bianchi A; de Lange T TRF1 promotes parallel pairing of telomeric tracts in vitro	52	65
495	129	230	3418 2000 CURRENT PHARMACEUTICAL DESIGN 6 (4): 441-471 Kerwin SM G-quadruplex DNA as a target for drug design	52	99
496	17	51	4410 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277 (43): 41110-41119 Opresko PL; von Kobbe C; Laine JP; Harrigan J; Hickson ID; et al. Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases	52	100
497	19	40	457 1987 CELL 48 (5): 779-788 YAO MC; ZHENG KQ; YAO CH A CONSERVED NUCLEOTIDE-SEQUENCE AT THE SITES OF DEVELOPMENTALLY REGULATED CHROMOSOMAL BREAKAGE IN TETRAHYMENA	51	63
498	21	48	740 1989 MOLECULAR AND CELLULAR BIOLOGY 9 (4): 1488-1497 RUNGE KW; ZAKIAN VA INTRODUCTION OF EXTRA TELOMERIC DNA-SEQUENCES INTO SACCHAROMYCES-CEREVISIAE RESULTS IN TELOMERE ELONGATION	51	79
499	11	53	833 1990 GENETICS 124 (3): 533-545 LOUIS EJ; HABER JE THE SUBTELOMERIC Y' REPEAT FAMILY IN SACCHAROMYCES-CEREVISIAE - AN EXPERIMENTAL SYSTEM FOR REPEATED SEQUENCE EVOLUTION	51	78
500	27	29	917 1990 SCIENCE 249 (4968): 489-490 BLACKBURN EH TELOMERES AND THEIR SYNTHESIS	51	51

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