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#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1301	22	70	1333 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268 (5): 3546-3554 PEARSON AM; RICH A; KRIEGER M POLYNUCLEOTIDE BINDING TO MACROPHAGE SCAVENGER RECEPTORS DEPENDS ON THE FORMATION OF BASE-QUARTET-STABILIZED 4-STRANDED HELICES	18	133
1302	11	15	1420 1994 CANCER GENETICS AND CYTOGENETICS 78 (1): 64-67 OHYASHIKI K; OHYASHIKI JH; FUJIMURA T; KAWAKUBO K; SHIMAMOTO T; et al. TELOMERE SHORTENING IN LEUKEMIC-CELLS IS RELATED TO THEIR GENETIC ALTERATIONS BUT NOT REPLICATIVE CAPABILITY	18	22
1303	24	55	1652 1995 EUROPEAN JOURNAL OF BIOCHEMISTRY 233 (2): 631-643 KENIRY MA; STRAHAN GD; OWEN EA; SHAFER RH SOLUTION STRUCTURE OF THE NA+ FORM OF THE DIMERIC GUANINE QUADRUPLEX [D(G(3)T(4)G(3))](2)	18	37
1304	23	30	1703 1995 JOURNAL OF EUKARYOTIC MICROBIOLOGY 42 (1): 32-43 ROMERO DP; BLACKBURN EH CIRCULAR RDNA REPLICONS PERSIST IN TETRAHYMENA-THERMOPHILA TRANSFORMANTS SYNTHESIZING GGGGTC TELOMERIC REPEATS	18	18
1305	27	32	1873 1996 CHEMISTRY & BIOLOGY 3 (11): 863-867 Hamilton SE; Corey DR Telomerase: Anti-cancer target or just a fascinating enzyme?	18	25
1306	43	59	2133 1997 BIOCHEMISTRY-MOSCOW 62 (11): 1216-1223 Price CM Synthesis of the telomeric C-strand. A review	18	20
1307	42	55	2195 1997 CLINICAL CHEMISTRY 43 (5): 708-714 Dahse R; Fiedler W; Ernst G Telomeres and telomerase: Biological and clinical importance	18	47
1308	13	39	2215 1997 EMBO JOURNAL 16 (12): 3715-3723 Higashiyama T; Noutoshi Y; Fujie M; Yamada T Zepp, a LINE-like retrotransposon accumulated in the Chlorella telomeric region	18	40
1309	5	49	2216 1997 EMBO JOURNAL 16 (15): 4788-4795 Teo SH; Jackson SP Identification of Saccharomyces cerevisiae DNA ligase .4. Involvement in DNA double-strand break repair	18	153
1310	39	52	2486 1998 BIOCHEMISTRY 37 (15): 5162-5172 Hammond PW; Cech TR Euplotes telomerase: Evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation	18	20
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1311	31	39	2510 1998 BRITISH JOURNAL OF HAEMATOLOGY 102 (5): 1367-1375 Xu DW; Gruber A; Peterson C; Pisa P Telomerase activity and the expression of telomerase components in acute myelogenous leukaemia	18	50
1312	23	61	2701 1998 JOURNAL OF MOLECULAR BIOLOGY 282 (3): 619-636 Kettani A; Bouaziz S; Gorin A; Zhao H; Jones RA; et al. Solution structure of a Na cation stabilized DNA quadruplex containing G center dot G center dot G center dot G and G center dot C center dot G center dot C tetrads formed by G-G-G-C repeats observed in adeno-associated viral DNA	18	55
1313	25	74	2809 1998 ONCOGENE 17 (6): 709-717 Gollahon LS; Kraus E; Wu TA; Yim SO; Strong LC; et al. Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts	18	34
1314	30	107	2835 1998 PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 59 59: 55-94 Shafer RH Stability and structure of model DNA triplexes and quadruplexes and their interactions with small ligands	18	55
1315	22	33	3024 1999 EUROPEAN JOURNAL OF CANCER 35 (6): 1027-1034 Murakami J; Nagai N; Shigemasa K; Ohama K Inhibition of telomerase activity and cell proliferation by a reverse transcriptase inhibitor in gynaecological cancer cell lines	18	22
1316	33	48	3032 1999 EXPERIMENTAL CELL RESEARCH 248 (1): 234-242 Mondello C; Petropoulou C; Monti D; Gonos ES; Franceschi C; et al. Telomere length in fibroblasts and blood cells from healthy centenarians	18	49
1317	28	75	3064 1999 GENETICS 152 (4): 1501-1512 Matsuura A; Naito T; Ishikawa F Genetic control of telomere integrity in Schizosaccharomyces pombe: rad3(+) and tel1(+) are parts of two regulatory networks independent of the downstream protein kinases chk1(+) and cds1(+)	18	42
1318	21	27	3083 1999 INTERNATIONAL JOURNAL OF CANCER 84 (4): 426-431 Park TW; Riethdorf S; Riethdorf L; Loning T; Janicke F Differential telomerase activity, expression of the telomerase catalytic sub-unit and telomerase-RNA in ovarian tumors	18	38
1319	44	68	3208 1999 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 429 (2): 209-223 Sprung CN; Afshar G; Chavez EA; Lansdorp P; Sabatier L; et al. Telomere instability in a human cancer cell line	18	20
1320	2	28	3515 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275 (37): 28349-28352 Li BM; Comai L Functional interaction between Ku and the Werner syndrome protein in DNA end processing	18	79
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1321	37	68	3652 2000 NEOPLASIA 2 (6): 540-554 Fouladi B; Sabatier L; Miller D; Pottier G; Murnane JP The relationship between spontaneous telomere loss and chromosome instability in a human turner cell line	18	26
1322	18	39	3824 2001 CURRENT BIOLOGY 11 (12): 962-966 Ranganathan V; Heine WF; Ciccone DN; Rudolph KL; Wu XH; et al. Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit	18	42
1323	9	42	4040 2001 MOLECULAR AND CELLULAR BIOLOGY 21 (12): 4046-4054 Tong WM; Hande MP; Lansdorp PM; Wang ZQ DNA strand break-sensing molecule poly(ADP-ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression	18	51
1324	31	72	4142 2001 RNA-A PUBLICATION OF THE RNA SOCIETY 7 (12): 1833-1844 Lukowiak AA; Narayanan A; Li ZH; Terns RM; Terns MP The snoRNA domain of vertebrate telomerase RNA functions to localize the RNA within the nucleus	18	29
1325	22	46	4438 2002 JOURNAL OF MEDICINAL CHEMISTRY 45 (3): 590-597 Heald RA; Modi C; Cookson JC; Hutchinson I; Laughton CA; et al. Antitumor polycyclic acridines. 8. Synthesis and telomerase-inhibitory activity of methylated pentacyclic acridinium salts	18	35
1326	41	54	4493 2002 MOLECULAR AND CELLULAR BIOLOGY 22 (16): 5679-5687 Tsai YL; Tseng SF; Chang SH; Lin CC; Teng SC Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination	18	19
1327	13	34	4551 2002 NUCLEIC ACIDS RESEARCH 30 (15): 3395-3400 Bundock P; van Attikum H; Hooykaas P Increased telomere length and hypersensitivity to DNA damaging agents in an Arabidopsis KU70 mutant	18	33
1328	9	61	4606 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 (2): 832-837 Li G; Nelsen C; Hendrickson EA Ku86 is essential in human somatic cells	18	54
1329	38	69	4701 2003 BIOESSAYS 25 (2): 126-133 Mason PJ Stem cells, telomerase and dyskeratosis congenita	18	28
1330	31	52	4714 2003 BLOOD 102 (3): 849-857 Roth A; Yssel H; Pene J; Chavez EA; Schertzer M; et al. Telomerase levels control the lifespan of human T lymphocytes	18	25
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1331	29	49	4745 2003 CANCER RESEARCH 63 (12): 3247-3256 Kim MY; Gleason-Guzman M; Izbicka E; Nishioka D; Hurley LH The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures	18	35
1332	16	32	4913 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (2): 836-842 Ramirez R; Carracedo J; Jimenez R; Canela A; Herrera E; et al. Massive telomere loss is an early event of DNA damage-induced apoptosis	18	44
1333	30	39	4954 2003 JOURNAL OF MOLECULAR BIOLOGY 326 (1): 117-125 Haider SM; Parkinson GN; Neidle S Structure of a G-quadruplex-ligand complex	18	30
1334	41	48	5030 2003 MOLECULAR CELL 11 (4): 1021-1032 Jacob NK; Kirk KE; Price CM Generation of telomeric G strand overhangs involves both G and C strand cleavage	18	22
1335	25	43	5033 2003 MOLECULAR CELL 11 (5): 1373-1378 Liti G; Louis EJ NEJ1 prevents NHEJ-dependent telornere fusions in yeast without telornerase	18	20
1336	32	47	5220 2004 BLOOD 104 (13): 3936-3942 Marrone A; Stevens D; Vulliamy T; Dokal I; Mason PJ Heterozygous telomerase RNA mutations found in dyskeratosis congenita and aplastic anemia reduce telomerase activity via haploinsufficiency	18	20
1337	11	24	5671 2004 SCIENCE 304 (5667): 97-100 Dynek JN; Smith S Resolution of sister telomere association is required for progression through mitosis	18	50
1338	3	57	108 1980 JOURNAL OF MOLECULAR BIOLOGY 142 (3): 289-313 ENGBERG J; DIN N; ECKERT WA; KAFFENBERGER W; PEARLMAN RE DETAILED TRANSCRIPTION MAP OF THE EXTRACHROMOSOMAL RIBOSOMAL-RNA GENES IN TETRAHYMENA-THERMOPHILA	17	42
1339	18	59	142 1982 CELL NUCLEUS 12: 127-153 YAO MC AMPLIFICATION OF RIBOSOMAL-RNA GENE IN TETRAHYMENA	17	19
1340	2	21	203 1983 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 80 (14): 4306-4310 RAIBAUD A; GAILLARD C; LONGACRE S; HIBNER U; BUCK G; et al. GENOMIC ENVIRONMENT OF VARIANT SURFACE-ANTIGEN GENES OF TRYPANOSOMA-EQUIPERDUM	17	41
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1341	6	45	266 1985 CELL 41 (2): 541-551 BONVEN BJ; GOCKE E; WESTERGAARD O A HIGH-AFFINITY TOPOISOMERASE-1 BINDING SEQUENCE IS CLUSTERED AT DNAASE-1 HYPERSENSITIVE SITES IN TETRAHYMENA R-CHROMATIN	17	227
1342	1	30	364 1986 EMBO JOURNAL 5 (13): 3705-3708 MONTANDON PE; WAGNER R; STUTZ E ESCHERICHIA-COLI RIBOSOMES WITH A C912 TO U BASE CHANGE IN THE 16S RIBOSOMAL-RNA ARE STREPTOMYCIN RESISTANT	17	79
1343	7	50	412 1986 MOLECULAR AND CELLULAR BIOLOGY 6 (7): 2364-2370 HARRISON GS; FINDLY RC; KARRER KM SITE-SPECIFIC METHYLATION OF ADENINE IN THE NUCLEAR GENOME OF A EUKARYOTE, TETRAHYMENA-THERMOPHILA	17	25
1344	20	48	424 1986 NUCLEIC ACIDS RESEARCH 14 (5): 2109-2122 YOKOYAMA R; YAO MC SEQUENCE CHARACTERIZATION OF TETRAHYMENA MACRONUCLEAR DNA ENDS	17	17
1345	4	34	513 1987 MAYO CLINIC PROCEEDINGS 62 (7): 558-567 DEWALD GW; DAHL RJ; SPURBECK JL; CARNEY JA; GORDON H CHROMOSOMALLY ABNORMAL CLONES AND NONRANDOM TELOMERIC TRANSLOCATIONS IN CARDIAC MYXOMAS	17	90
1346	3	51	537 1987 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 84 (21): 7383-7387 WEINER AM; MAIZELS N TRANSFER RNA-LIKE STRUCTURES TAG THE 3' ENDS OF GENOMIC RNA MOLECULES FOR REPLICATION - IMPLICATIONS FOR THE ORIGIN OF PROTEIN-SYNTHESIS	17	187
1347	6	21	620 1988 MOLECULAR AND BIOCHEMICAL PARASITOLOGY 28 (2): 85-94 VERNICK KD; MCCUTCHAN TF SEQUENCE AND STRUCTURE OF A PLASMODIUM-FALCIPARUM TELOMERE	17	44
1348	3	17	699 1989 EMBO JOURNAL 8 (4): 1213-1216 DESTASIO EA; MOAZED D; NOLLER HF; DAHLBERG AE MUTATIONS IN 16S RIBOSOMAL-RNA DISRUPT ANTIBIOTIC - RNA INTERACTIONS	17	80
1349	8	50	824 1990 EMBO JOURNAL 9 (2): 505-514 ROUYER F; DELACHAPELLE A; ANDERSSON M; WEISSENBACH J AN INTERSPERSED REPEATED SEQUENCE SPECIFIC FOR HUMAN SUBTELOMERIC REGIONS	17	88
1350	26	36	1159 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267 (22): 15293-15300 GUO Q; LU M; KALLENBACH NR ADENINE AFFECTS THE STRUCTURE AND STABILITY OF TELOMERIC SEQUENCES	17	22
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1351	11	34	1203 1992 NUCLEIC ACIDS RESEARCH 20 (7): 1491-1496 SCHERF A; MATTEI D CLONING AND CHARACTERIZATION OF CHROMOSOME BREAKPOINTS OF PLASMODIUM-FALCIPARUM - BREAKAGE AND NEW TELOMERE FORMATION OCCURS FREQUENTLY AND RANDOMLY IN SUBTELOMERIC GENES	17	41
1352	21	27	1297 1993 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 22 (4): 245-249 DAY JP; MARDER BA; MORGAN WF TELOMERES AND THEIR POSSIBLE ROLE IN CHROMOSOME STABILIZATION	17	34
1353	30	48	1444 1994 EMBO JOURNAL 13 (4): 993-1001 MURCHIE AIH; LILLEY DMJ TETRAPLEX FOLDING OF TELOMERE SEQUENCES AND THE INCLUSION OF ADENINE BASES	17	40
1354	8	21	1470 1994 GENETICS 136 (4): 1319-1324 YOU Y; SCOTT J; FORNEY J THE ROLE OF MACRONUCLEAR DNA-SEQUENCES IN THE PERMANENT RESCUE OF A NON-MENDELIAN MUTATION IN PARAMECIUM-TETRAURELIA	17	24
1355	11	73	1493 1994 JOURNAL OF CELL BIOLOGY 127 (2): 273-285 SCHERTHAN H; BAHLER J; KOHLI J DYNAMICS OF CHROMOSOME ORGANIZATION AND PAIRING DURING MEIOTIC PROPHASE IN FISSION YEAST	17	83
1356	28	55	1557 1994 NUCLEIC ACIDS RESEARCH 22 (24): 5310-5320 GILSON E; MULLER T; SOGO J; LAROCHE T; GASSER SM RAP1 STIMULATES SINGLE-STRAND TO DOUBLE-STRAND ASSOCIATION OF YEAST TELOMERIC DNA - IMPLICATIONS FOR TELOMERE-TELOMERE INTERACTIONS	17	24
1357	11	25	1694 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270 (35): 20692-20697 FRANTZ JD; GILBERT W A NOVEL YEAST GENE-PRODUCT, G4P1, WITH A SPECIFIC AFFINITY FOR QUADRUPLEX NUCLEIC-ACIDS	17	41
1358	19	20	1695 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270 (37): 21453-21456 LUE NF; WANG JC ATP-DEPENDENT PROCESSIVITY OF A TELOMERASE ACTIVITY FROM SACCHAROMYCES-CEREVISIAE	17	17
1359	83	120	1865 1996 CANCER SURVEYS 28: 197-216 Bacchetti S Telomere maintenance in tumour cells	17	30
1360	11	57	1909 1996 GENES & DEVELOPMENT 10 (5): 634-645 Zou S; Ke N; Kim JM; Voytas DF The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci	17	90
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1361	20	37	2159 1997 CANCER 79 (8): 1552-1560 Iwama H; Ohyashiki K; Ohyashiki JH; Hayashi S; Kawakubo K; et al. The relationship between telomere length and therapy-associated cytogenetic responses in patients with chronic myeloid leukemia	17	31
1362	35	44	2213 1997 EMBO JOURNAL 16 (11): 3233-3242 McCormickGraham M; Haynes WJ; Romero DP Variable telomeric repeat synthesis in Paramecium tetraurelia is consistent with misincorporation by telomerase	17	19
1363	12	30	2230 1997 EUROPEAN JOURNAL OF CANCER 33 (12): 1932-1936 Hiyama E; Hiyama K; Ohtsu K; Yamaoka H; Ichikawa T; et al. Telomerase activity in neuroblastoma: is it a prognostic indicator of clinical behaviour?	17	37
1364	23	29	2270 1997 GYNECOLOGIC ONCOLOGY 64 (1): 171-175 Zheng PS; Iwasaka T; Yamasaki F; Ouchida M; Yokoyama M; et al. Telomerase activity in gynecologic tumors	17	33
1365	17	36	2304 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (39): 24631-24636 Harrington C; Lan Y; Akman SA The identification and characterization of a G4-DNA resolvase activity	17	29
1366	13	27	2312 1997 JOURNAL OF CLINICAL ONCOLOGY 15 (5): 1932-1937 Pao CC; Tseng CJ; Lin CY; Yang FP; Hor JJ; et al. Differential expression of telomerase activity in human cervical cancer and cervical intraepithelial neoplasia lesions	17	34
1367	16	21	2506 1998 BRITISH JOURNAL OF CANCER 77 (10): 1633-1637 Sano T; Asai A; Mishima K; Fujimaki T; Kirino T Telomerase activity in 144 brain tumours	17	29
1368	45	72	2666 1998 INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 73 (1): 1-13 Slijepcevic P; Bryant PE Chromosome healing, telomere capture and mechanisms of radiation-induced chromosome breakage	17	37
1369	17	27	2707 1998 JOURNAL OF ORAL PATHOLOGY & MEDICINE 27 (3): 111-115 Sumida T; Sogawa K; Hamakawa H; Sugita A; Tanioka H; et al. Detection of telomerase activity in oral lesions	17	23
1370	23	40	2764 1998 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 404 (1-2): 205-214 Hande MP; Lansdorp PM; Natarajan AT Induction of telomerase activity by in vivo X-irradiation of mouse splenocytes and its possible role in chromosome healing	17	26
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1371	14	28	2788 1998 NUCLEIC ACIDS RESEARCH 26 (9): 2161-2167 Fu GL; Barker DC Characterisation of Leishmania telomeres reveals unusual telomeric repeats and conserved telomere-associated sequence	17	30
1372	23	29	2826 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (10): 5667-5671 Henning KA; Moskowitz N; Ashlock MA; Liu PP Humanizing the yeast telomerase template	17	22
1373	27	37	2912 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 263 (2): 308-314 Kakuo S; Asaoka K; Ide T Human is a unique species among primates in terms of telomere length	17	23
1374	38	67	2917 1999 BIOCHEMISTRY 38 (14): 4355-4364 Marathias VM; Bolton PH Determinants of DNA quadruplex structural type: Sequence and potassium binding	17	50
1375	19	30	2940 1999 BONE MARROW TRANSPLANTATION 24 (4): 411-415 Lee JJ; Kook H; Chung IJ; Kim HJ; Park MR; et al. Telomere length changes in patients undergoing hematopoietic stem cell transplantation	17	34
1376	23	59	2947 1999 BRITISH JOURNAL OF HAEMATOLOGY 105 (4): 883-893 Leteurtre F; Li X; Guardiola P; Le Roux G; Sergere JC; et al. Accelerated telomere shortening and telomerase activation in Fanconi's anaemia	17	38
1377	67	90	3016 1999 DRUG DISCOVERY TODAY 4 (4): 155-161 Pitts AE; Corey DR The telomerase challenge - an unusual problem in drug discovery	17	23
1378	31	81	3146 1999 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 121 (23): 5519-5534 Spackova N; Berger I; Sponer J Nanosecond molecular dynamics simulations of parallel and antiparallel guanine quadruplex DNA molecules	17	78
1379	9	26	3223 1999 NUCLEIC ACIDS RESEARCH 27 (12): 2457-2464 Patel PK; Hosur RV NMR observation of T-tetrads in a parallel stranded DNA quadruplex formed by Saccharomyces cerevisiae telomere repeats	17	46
1380	27	58	3391 2000 CHROMOSOMA 109 (6): 372-380 Biessmann H; Zurovcova M; Yao JG; Lozovskaya E; Walter MF A telomeric satellite in Drosophila virilis and its sibling species	17	24
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1381	15	57	3413 2000 CURRENT OPINION IN CELL BIOLOGY 12 (6): 705-709 Lundberg AS; Hahn WG; Gupta P; Weinberg RA Genes involved in senescence and immortalization	17	92
1382	44	76	3582 2000 MECHANISMS OF AGEING AND DEVELOPMENT 118 (1-2): 23-34 Lansdorp PM Repair of telomeric DNA prior to replicative senescence	17	33
1383	15	19	3691 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97 (12): 6367-6372 Haering CH; Nakamura TM; Baumann P; Cech TR Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomyces pombe	17	19
1384	15	78	3863 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268 (10): 2784-2791 Itahana K; Dimri G; Campisi J Regulation of cellular senescence by p53	17	83
1385	18	33	4131 2001 PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES 268 (1476): 1541-1546 Adams SP; Hartman TPV; Lim KY; Chase MW; Bennett MD; et al. Loss and recovery of Arabidopsis-type telomere repeat sequences 5 '- (TTTAGGG)(n)-3 ' in the evolution of a major radiation of flowering plants	17	25
1386	13	35	4328 2002 FASEB JOURNAL 16 (9): 935-942 Wiemann SU; Satyanarayana A; Tsahuridu M; Tillmann HL; Zender L; et al. Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis	17	36
1387	25	86	4348 2002 GENETICS 161 (4): 1437-1452 Nakamura TM; Moser BA; Russell P Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres	17	33
1388	43	55	4495 2002 MOLECULAR AND CELLULAR BIOLOGY 22 (17): 6234-6246 Banik SSR; Guo CH; Smith AC; Margolis SS; Richardson DA; et al. C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity	17	19
1389	40	105	4569 2002 ONCOGENE 21 (4): 512-521 Tham WH; Zakian VA Transcriptional silencing at Saccharomyces telomeres: implications for other organisms	17	38
1390	17	39	4587 2002 ONCOGENE 21 (23): 3784-3791 Xiang H; Wang J; Mao YW; Liu MY; Reddy VN; et al. Human telomerase accelerates growth of lens epithelial cells through regulation of the genes mediating RB/E2F pathway	17	27
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1391	18	37	4740 2003 CANCER RESEARCH 63 (3): 579-585 Mo YQ; Gan YB; Song SH; Johnston J; Xiao XD; et al. Simultaneous targeting of telomeres and telomerase as a cancer therapeutic approach	17	22
1392	27	50	4749 2003 CANCER RESEARCH 63 (18): 5917-5925 Chen Z; Koeneman KS; Corey DR Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells	17	24
1393	84	128	5042 2003 MOLECULES AND CELLS 15 (2): 164-175 Djojosubroto MW; Choi YS; Lee HW; Rudolph KL Telomeres and telomerase in aging, regeneration and cancer	17	26
1394	23	38	5109 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (19): 10854-10859 Mieczkowski PA; Mieczkowska JO; Dominska M; Petes TD Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae	17	25
1395	42	57	5382 2004 GENES & DEVELOPMENT 18 (4): 387-396 Lin J; Blackburn EH Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA	17	17
1396	11	19	5385 2004 GENES & DEVELOPMENT 18 (12): 1391-1396 Larrivee M; LeBel C; Wellinger RJ The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex	17	24
1397	20	34	5433 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (2): 1442-1448 Iwano T; Tachibana M; Reth M; Shinkai Y Importance of TRF1 for functional telomere structure	17	25
1398	42	66	5529 2004 MOLECULAR AND CELLULAR BIOLOGY 24 (4): 1595-1607 Dantzer F; Giraud-Panis MJ; Jaco I; Ame JC; Schultz I; et al. Functional interaction between poly(ADP-ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2	17	44
1399	21	37	5572 2004 NATURE GENETICS 36 (1): 46-54 Schramke V; Luciano P; Brevet V; Guillot S; Corda Y; et al. RPA regulates telomerase action by providing Est1p access to chromosome ends	17	22
1400	34	41	6071 2005 MOLECULAR AND CELLULAR BIOLOGY 25 (2): 808-818 Kelleher C; Kurth I; Lingner J Human protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitro	17	20

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