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Mon Dec 13 12:29:51 2004
The cytidine deaminase CEM15 induces hypermutation
in newly synthesized HIV-1 DNA

Zhang H, Yang B, Pomerantz RJ, Zhang CM, Arunachalam SC, Gao L
NATURE 424 (6944): 94-98 JUL 3 2003
and the citing papers

Nodes: 89, Authors: 309, Journals: 48, Outer References: 2376, Words: 353
Collection span: 2003 - 2004
View: Overview. Sorted by NCR.
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
1632636 2004 FRONTIERS IN BIOSCIENCE 9:2388-2413
Seelamgari A; Maddukuri A; Berro R; de la Fuente C; Kehn K; et al.
Role of viral regulatory and accessory proteins in HIV-1 replication
00
2123731 2004 CURRENT PHARMACEUTICAL DESIGN 10(30):3725-3739
Muriaux D; Darlix JL; Cimarelli A
Targeting the assembly of the human immunodeficiency virus type I
01
3417155 2004 JOURNAL OF MOLECULAR MEDICINE-JMM 82(5):280-297
Krokan HE; Kavli B; Slupphaug G
Novel aspects of macromolecular repair and relationship to human disease
02
4112439 2004 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 36(9):1716-1734
Rezende LF; Prasad VR
Nucleo side-analog resistance mutations in HIV-1 reverse transcriptase and their influence on polymerase fidelity and viral mutation rates
00
5111814 2003 NATURE REVIEWS MICROBIOLOGY 1(3):181-190
Simon V; Ho DD
HIV-1 dynamics in vivo: Implications for therapy
00
62510672 2004 NATURE REVIEWS IMMUNOLOGY 4(11):868-877
Harris RS; Liddament MT
Retroviral restriction by APOBEC proteins
00
71910171 2004 NATURE IMMUNOLOGY 5(11):1109-1115
Bieniasz PD
Intrinsic immunity: a front-line defense against viral attack
00
8129664 2004 JOURNAL OF VIROLOGY 78(21):11841-11852
Luo K; Liu BD; Xiao ZX; Yu YK; Yu XH; et al.
Amino-terminal region of the human immunodeficiency virus type 1 nucleocapsid is required for human APOBEC3G packaging
00
939518 2004 AIDS 18(9):1231-1240
Nolan D; Gaudieri S; John M; Mallal S
Impact of host genetics on HIV disease progression and treatment: new conflicts on an ancient battleground
00
1018167 2004 JOURNAL OF VIROLOGY 78(22):12537-12547
Baumann JG; Unutmaz D; Miller MD; Breun SKJ; Grill SM; et al.
Murine T cells potently restrict human immunodeficiency virus infection
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
1168050 2004 JOURNAL OF IMMUNOLOGY 172(11):6513-6518
Cascalho M
Advantages and disadvantages of cytidine deamination
00
1217953 2004 JOURNAL OF MEDICAL VIROLOGY 73(3):350-361
Pariente N; Pernas M; de la Rosa R; Gomez-Mariano G; Fernandez G; et al.
Long-term suppression of plasma viremia with highly active antiretroviral therapy despite virus evolution and very limited selection of drug-resistant genotypes
01
1327085 2004 TRENDS IN MICROBIOLOGY 12(4):170-177
Freed EO
HIV-1 and the host cell: an intimate association
00
14137086 2004 TRENDS IN MOLECULAR MEDICINE 10(6):291-297
Rose KM; Marin M; Kozak SL; Kabat D
The viral infectivity factor (Vif) of HIV-1 unveiled
11
1556656 2004 JOURNAL OF VIROLOGY 78(4):2072-2081
Liu BD; Yu XH; Luo K; Yu YK; Yu XF
Influence of primate lentiviral vif and proteasome inhibitors on human immunodeficiency virus type 1 virion packaging of APOBEC3G
99
1646463 2004 JOURNAL OF VIROLOGY 78(21):11632-11640
Devaux P; Cattaneo R
Measles virus phosphoprotein gene products: Conformational flexibility of the P/V protein amino-terminal domain and C protein infectivity factor function
00
17126247 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(40):41744-41749
Rose KM; Marin M; Kozak SL; Kabat D
Transcriptional regulation of APOBEC3G, a cytidine deaminase that hypermutates human immunodeficiency virus
00
1815960 2004 JOURNAL OF VIROLOGY 78(17):8971-8982
de Rozieres S; Mathiason CK; Rolston MR; Chatterji U; Hoover EA; et al.
Characterization of a highly pathogenic molecular clone of feline immunodeficiency virus clade C
00
19125974 2004 NUCLEIC ACIDS RESEARCH 32(8):2421-2429
Suspene R; Sommer P; Henry M; Ferris S; Guetard D; et al.
APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase
00
2015754 2004 JOURNAL OF MOLECULAR BIOLOGY 337(3):585-596
Beale RCL; Petersen-Mahrt SK; Watt IN; Harris RS; Rada C; et al.
Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: Correlation with mutation spectra in vivo
712
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
2115787 2004 VIROLOGY 318(1):350-359
Kristbjornsdottir HB; Andresdottir V; Svansson V; Torsteinsdottir S; Matthiasdottir S; et al.
The vif gene of maedi-visna virus is essential for infectivity in vivo and in vitro
00
2225788 2004 VIROLOGY 326(2):262-279
Dykes C; Balakrishnan M; Planelles V; Zhu YH; Bambara RA; et al.
Identification of a preferred region for recombination and mutation in HIV-1 gag
00
2395344 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(32):33177-33184
Cen S; Guo F; Niu MJ; Saadatmand J; Deflassieux J; et al.
The interaction between HIV-1 Gag and APOBEC3G
44
2425270 2004 MICROBIOLOGICA 27(3):207-214
Clementi M
Can modulation of viral fitness represent a target for anti-HIV-1 strategies?
00
25115037 2004 HUMAN MOLECULAR GENETICS 13(16):1785-1791
Zhang JZ; Webb DM
Rapid evolution of primate antiviral enzyme APOBEC3G
12
26115075 2004 PLOS BIOLOGY 2(9):1278-1285
Sawyer SL; Emerman M; Malik HS
Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G
00
2724943 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(27):28419-28425
Chen RX; Le Rouzic E; Kearney JA; Mansky LM; Benichou S
Vpr-mediated incorporation of UNG2 into HIV-1 particles is required to modulate the virus mutation rate and for replication in macrophages
00
28154965 2004 JOURNAL OF VIROLOGY 78(21):12041-12046
Gaddis NC; Sheehy AM; Ahmad KM; Swanson CM; Bishop KN; et al.
Further investigation of simian immunodeficiency virus vif function in human cells
00
291471 2003 AIDS RESEARCH AND HUMAN RETROVIRUSES 19(12):1115-1123
Koulinska IN; Chaplin B; Mwakagile D; Essex M; Renjifo B
Hypermutation of HIV type 1 genomes isolated from infants soon after vertical infection
00
301476 2003 JOURNAL OF VIROLOGY 77(21):11398-11407
Kao S; Khan MA; Miyagi E; Plishka R; Buckler-White A; et al.
The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity
2124
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
3114757 2004 JOURNAL OF VIROLOGY 78(5):2426-2433
Gao F; Chen Y; Levy DN; Conway JA; Kepler TB; et al.
Unselected mutations in the human immunodeficiency virus type 1 genome are mostly nonsynonymous and often deleterious
23
3284641 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(13):12355-12362
Akari H; Fujita M; Kao S; Khan MA; Shehu-Xhilaga M; et al.
High level expression of human immunodeficiency virus type-1 Vif inhibits viral infectivity by modulating proteolytic processing of the gag precursor at the p2/nucleocapsid processing site
22
331457 2003 MOLECULAR CELL 12(2):501-508
Barreto V; Reina-San-Martin B; Ramiro AR; McBride KM; Nussenzweig MC
C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion
320
3444524 2004 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1680(1):11-23
Dur S; Krause K; Pluntke N; Greeve J
Gene structure and expression of the mouse APOBEC-1 complementation factor: multiple transcriptional initiation sites and a spliced variant with a premature stop translation codon
00
3574528 2004 CURRENT OPINION IN IMMUNOLOGY 16(4):477-482
Navarro F; Landau NR
Recent insights into HIV-1 Vif
12
3644561 2004 JOURNAL OF VIROLOGY 78(19):10574-10581
Feng F; Davis A; Lake JA; Carr J; Xia W; et al.
Ring finger protein ZIN interacts with human immunodeficiency virus type 1 Vif
00
3714280 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(19):7352-7356
Wang CL; Harper RA; Wabl M
Genome-wide somatic hypermutation
03
3814012 2003 NATURE MEDICINE 9(11):1398-1403
Marin M; Rose KM; Kozak SL; Kabat D
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
4655
3953940 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(9):7792-7798
Mehle A; Strack B; Ancuta P; Zhang CS; McPike M; et al.
Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway
1313
4013952 2004 JOURNAL OF INFECTIOUS DISEASES 189(4):567-571
Pomerantz RJ
HIV-1 infection and genomics: Sorting out the complexity
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
4133983 2004 TRENDS IN GENETICS 20(6):224-227
Smith HC; Bottaro A; Sowden MP; Wedekind JE
Activation induced deaminase: the importance of being specific
00
4263830 2004 CURRENT OPINION IN MICROBIOLOGY 7(5):555-559
Trkola A
HIV-host interactions: vital to the virus and key to its inhibition (vol 7, pg 555, 2004)
11
4313721 2004 ANALYTICAL BIOCHEMISTRY 328(1):44-50
Agrawal N; Mihai C; Kohen A
Microscale synthesis of isotopically labeled R-[6-H-X]N-5,N-10-methylene-5,6,7,8-tetrahydrofolate as a cofactor for thymidylate synthase
01
4453729 2004 CURRENT OPINION IN MICROBIOLOGY 7(4):407-411
Trkola A
HIV-host interactions: vital to the virus and key to its inhibition
00
4593758 2004 JOURNAL OF VIROLOGY 78(11):6073-6076
Zheng YH; Irwin D; Kurosu T; Tokunaga K; Sata T; et al.
Human APOBEC3F is another host factor that blocks human immunodeficiency virus type 1 replication
910
4613781 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(29):10774-10779
Hatziioannou T; Perez-Caballero D; Yang A; Cowan S; Bieniasz PD
Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5 alpha
14
4713627 2004 CURRENT OPINION IN GENETICS & DEVELOPMENT 14(1):5-10
Friedberg EC; McDaniel LD; Schultz RA
The role of endogenous and exogenous DNA damage and mutagenesis
03
4823651 2004 JOURNAL OF IMMUNOLOGY 173(5):3223-3229
Arudchandran A; Bernstein RM; Max EE
Single-stranded DNA breaks adjacent to cytosines occur during Ig gene class switch recombination
01
4953673 2004 NATURE STRUCTURAL & MOLECULAR BIOLOGY 11(5):435-442
Yu Q; Konig R; Pillai S; Chiles K; Kearney M; et al.
Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome
1011
50163425 2004 CURRENT BIOLOGY 14(15):1385-1391
Liddament MT; Brown WL; Schumacher AJ; Harris RS
APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo
34
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
5183469 2004 MICROBES AND INFECTION 6(9):791-798
Fujita M; Akari H; Sakurai A; Yoshida A; Chiba T; et al.
Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome degradation
00
52163345 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(33):34083-34086
Alce TM; Popik W
APOBEC3G is incorporated into virus-like particles by a direct interaction with HIV-1 Gag nucleocapsid protein
22
53103346 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(34):35822-35828
Svarovskaia ES; Xu HZ; Mbisa JL; Barr R; Gorelick RJ; et al.
Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 Virions through interactions with viral and nonviral RNAs
33
5493359 2004 JOURNAL OF VIROLOGY 78(15):8238-8244
Kobayashi M; Takaori-Kondo A; Shindo K; Abudu A; Fukunaga K; et al.
APOBEC3G targets specific virus species
11
5543362 2004 JOURNAL OF VIROLOGY 78(20):11070-11076
An P; Bleiber G; Duggal P; Nelson G; May M; et al.
APOBEC3G genetic variants and their influence on the progression to AIDS
00
56113233 2004 EMBO JOURNAL 23(12):2451-2458
Wiegand HL; Doehle BP; Bogerd HP; Cullen BR
A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins
67
5783279 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(15):5652-5657
Xu HZ; Svarovskaia ES; Barr R; Zhang YJ; Khan MA; et al.
A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion
88
5853122 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 315(1):66-72
Dussart S; Courcoul M; Bessou G; Douaisi M; Duverger Y; et al.
The Vif protein of human immunodeficiency virus type 1 is posttranslationally modified by ubiquitin
11
591308 2003 MOLECULAR CELL 12(3):591-601
Stopak K; de Noronha C; Yonemoto W; Greene WC
HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability
4250
6003011 2003 NATURE 424(6944):94-98
Zhang H; Yang B; Pomerantz RJ; Zhang CM; Arunachalam SC; et al.
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
8888
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
61123026 2004 CURRENT BIOLOGY 14(15):1392-1396
Bishop KN; Holmes RK; Sheehy AM; Davidson NO; Cho SJ; et al.
Cytidine deamination of retroviral DNA by diverse APOBEC proteins
45
6263078 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(11):3927-3932
Schrofelbauer R; Chen D; Landau NR
A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif)
00
6312915 2003 SCIENCE 301(5635):923-925
KewalRamani VN; Coffin JM
Weapons of mutational destruction
37
6442932 2004 DNA REPAIR 3(1):85-89
Bhagwat AS
DNA-cytosine deaminases: from antibody maturation to antiviral defense
01
6542949 2004 JOURNAL OF CELLULAR BIOCHEMISTRY 92(3):560-572
Li JL; Potash MJ; Volsky DJ
Functional domains of APOBEC3G required for antiviral activity
11
6682877 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(11):3770-3774
Bogerd HP; Doehle BP; Wiegand HL; Cullen BR
A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor
1616
6712716 2003 SCIENCE 302(5647):1056-1060
Yu XH; Yu YK; Liu BD; Luo K; Kong W; et al.
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex
4047
681265 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(45):44412-44416
Shindo K; Takaori-Kondo A; Kobayashi M; Abudu A; Fukunaga K; et al.
The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity
99
6912635 2004 EUROPEAN JOURNAL OF IMMUNOLOGY 34(3):844-849
Fugmann SD; Rush JS; Schatz DG
Non-redundancy of cytidine deaminases in class switch recombination
02
7012513 2003 NATURE MEDICINE 9(11):1404-1407
Sheehy AM; Gaddis NC; Malim MH
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif
4652
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
711243 2003 CHEMICAL PHYSICS LETTERS 381(5-6):660-665
Kedzierski P; Sokalski WA; Cheng HS; Mitchell J; Leszczynski J
DFT study of the reaction proceeding in the cytidine deaminase
01
7262448 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(42):43371-43373
Turelli P; Vianin S; Trono D
The innate antiretroviral factor APOBEC3G does not affect human LINE-1 retrotransposition in a cell culture assay
00
7392466 2004 JOURNAL OF VIROLOGY 78(21):12058-12061
Zennou W; Perez-Caballero D; Gottlinger H; Bieniasz PD
APOBEC3G incorporation into human immunodeficiency virus type 1 particles
00
7462476 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(11):3725-3726
Kaiser SM; Emerman M
Controlling lentiviruses: Single amino acid changes can determine specificity
00
7542484 2004 TRENDS IN MICROBIOLOGY 12(4):145-148
Argyris EG; Pomerantz RJ
HIV-1 Vif versus APOBEC3G: newly appreciated warriors in the ancient battle between virus and host
00
76112334 2004 EMBO REPORTS 5(7):679-680
Trono D
Retroviruses under editing crossfire - A second member of the human APOBEC3 family is a Vif-blockable innate antiretroviral factor
00
7712238 2004 IMMUNOLOGY LETTERS 91(1):1-2
Suslov KV
Does AID aid AIDS?
00
782214 2003 CURRENT BIOLOGY 13(22):2009-2013
Conticello SG; Harris RS; Neuberger MS
The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G
2426
7972123 2004 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 321(3):566-573
Douaisi M; Dussart S; Courcoul M; Bessou G; Vigne R; et al.
HIV-1 and MLV Gag proteins are sufficient to recruit APOBEC3G into virus-like particles
00
801202 2003 CELL 114(3):281-283
Goff SP
Death by deamination: A novel host restriction system for HIV-1
69
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
8112017 2003 TRENDS IN MOLECULAR MEDICINE 9(10):409-413
Vartanian JP; Sommer P; Wain-Hobson S
Death and the retrovirus
89
82102089 2004 VIROLOGY 328(2):163-168
Schafer A; Bogerd HP; Cullen BR
Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor
00
8331982 2004 REVIEWS IN MEDICAL VIROLOGY 14(1):1-2
Griffiths PD
From restriction factors to restriction enzymes
00
8411810 2003 NATURE 424(6944):21-22
Gu YP; Sundquist WI
Good to CU
66
8561742 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(15):14481-14483
Mangeat B; Turelli P; Liao SY; Trono D
A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to vif action
1010
8631619 2004 AIDS 18(13):1861-1863
Berkhout B; de Ronde A
APOBEC3G versus reverse transcriptase in the generation of HIV-1 drug-resistance mutations
00
871159 2003 MOLECULAR THERAPY 8(4):525-527
Cullen BR
HIV-1 Vif: Counteracting innate antiretroviral defenses
12
8831420 2004 AIDS 18(13):1863-1865
Min W; Hui X; Hong KX; Huang HL; Tang HL; et al.
Biased G-to-A hypermutation in HIV-1 proviral DNA from a long-term non-progressor
00
8951068 2004 M S-MEDECINE SCIENCES 20(2):139-141
Schwartz O
HIV-1, a very Vif virus
00

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