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Fri Sep 15 15:09:29 2006

Papers by EH Blackburn

Collection span: 1972 - 2006

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# LCR NCR Node / Date / Journal / Author LCS GCS
101 10 37 90 1994 JUN [15] GENETICS 137 (2): 455-466
KAPLER GM; ORIAS E; BLACKBURN EH
TETRAHYMENA-THERMOPHILA MUTANTS DEFECTIVE IN THE DEVELOPMENTALLY PROGRAMMED MATURATION AND MAINTENANCE OF THE RDNA MINICHROMOSOME
3 14
102 7 50 88 1994 DEC 1 EMBO JOURNAL 13 (23): 5721-5731
BHATTACHARYYA A; BLACKBURN EH
ARCHITECTURE OF TELOMERASE RNA
8 46
103 19 66 103 1995 JAN 1 GENES & DEVELOPMENT 9 (1): 59-71
KIRK KE; BLACKBURN EH
AN UNUSUAL SEQUENCE ARRANGEMENT IN THE TELOMERES OF THE GERM-LINE MICRONUCLEUS IN TETRAHYMENA-THERMOPHILA
8 19
104 0 0 105 1995 JAN 5 JOURNAL OF CELLULAR BIOCHEMISTRY : 209-209
GILLEY D; LEE MS; BLACKBURN EH
TEMPLATE FUNCTION IN THE TELOMERASE RNA OF TETRAHYMENA
0 0
105 16 30 106 1995 JAN-FEB [JAN 15] JOURNAL OF EUKARYOTIC MICROBIOLOGY 42 (1): 32-43
ROMERO DP; BLACKBURN EH
CIRCULAR RDNA REPLICONS PERSIST IN TETRAHYMENA-THERMOPHILA TRANSFORMANTS SYNTHESIZING GGGGTC TELOMERIC REPEATS
10 18
106 7 32 109 1995 MAY 11 NUCLEIC ACIDS RESEARCH 23 (9): 1561-1569
PAN WJ; BLACKBURN EH
TANDEM REPEATS OF THE 5' NONTRANSCRIBED SPACER OF TETRAHYMENA RDNA FUNCTION AS HIGH COPY NUMBER AUTONOMOUS REPLICONS IN THE MACRONUCLEUS BUT DO NOT PREVENT RIBOSOMAL-RNA GENE DOSAGE REGULATION
1 10
107 9 33 107 1995 JUN [15] MOLECULAR AND CELLULAR BIOLOGY 15 (6): 3372-3381
PAN WJ; GALLAGHER RC; BLACKBURN EH
REPLICATION OF AN RIBOSOMAL-RNA GENE ORIGIN PLASMID IN THE TETRAHYMENA-THERMOPHILA MACRONUCLEUS IS PREVENTED BY TRANSCRIPTION THROUGH THE ORIGIN FROM AN RNA-POLYMERASE-I PROMOTER
2 19
108 0 0 111 1995 [JUN 30] TELOMERES
BLACKBURN EH; GREIDER CW
Telomeres (Monograph 29), edited by Elizabeth H. Blackburn and Carol W. Greider.
12 159
109 14 30 110 1995 JUL 21 SCIENCE 269 (5222): 396-400
COHN M; BLACKBURN EH
TELOMERASE IN YEAST
25 170
110 12 43 108 1995 AUG 3 NATURE 376 (6539): 403-409
MCEACHERN MJ; BLACKBURN EH
RUNAWAY TELOMERE ELONGATION CAUSED BY TELOMERASE RNA GENE-MUTATIONS
33 241
# LCR NCR Node / Date / Journal / Author LCS GCS
111 15 37 104 1995 SEP 15 GENES & DEVELOPMENT 9 (18): 2214-2226
GILLEY D; LEE MS; BLACKBURN EH
ALTERING SPECIFIC TELOMERASE RNA TEMPLATE RESIDUES AFFECTS ACTIVE-SITE FUNCTION
26 86
112 12 49 113 1996 JAN [15] MOLECULAR AND CELLULAR BIOLOGY 16 (1): 53-65
Strahl C; Blackburn EH
Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines
9 231
113 15 35 114 1996 JAN [15] MOLECULAR AND CELLULAR BIOLOGY 16 (1): 66-75
Gilley D; Blackburn EH
Specific RNA residue interactions required for enzymatic functions of Tetrahymenatelomerase
20 68
114 3 4 116 1996 FEB [15] SCIENTIFIC AMERICAN 274 (2): 92-97
Greider CW; Blackburn EH
Telomeres, telomerase and cancer
1 103
115 11 56 112 1996 JUL 15 GENES & DEVELOPMENT 10 (14): 1822-1834
McEachern MJ; Blackburn EH
Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase
23 159
116 3 19 115 1996 SEP 26 NATURE 383 (6598): 354-357
Krauskopf A; Blackburn EH
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
30 116
117 16 49 119 1997 FEB 15 GENES & DEVELOPMENT 11 (4): 528-540
Prescott J; Blackburn EH
Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro
37 99
118 13 50 118 1997 FEB 17 EMBO JOURNAL 16 (4): 866-879
Wang H; Blackburn EH
De nova telomere addition by Tetrahymena telomerase in vitro
4 58
119 6 29 124 1997 MAR 7 SCIENCE 275 (5305): 1478-1481
Kirk KE; Harmon BP; Reichardt IK; Sedat JW; Blackburn EH
Block in anaphase chromosome separation caused by a telomerase template mutation
19 157
120 3 29 122 1997 APR 1 NUCLEIC ACIDS RESEARCH 25 (7): 1426-1431
Bhattacharyya A; Blackburn EH
Aspergillus nidulans maintains short telomeres throughout development
0 14
# LCR NCR Node / Date / Journal / Author LCS GCS
121 8 29 123 1997 APR 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (7): 2823-2827
Bhattacharyya A; Blackburn EH
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains
9 39
122 11 66 120 1997 NOV 1 GENES & DEVELOPMENT 11 (21): 2790-2800
Prescott J; Blackburn EH
Functionally interacting telomerase RNAs in the yeast telomerase complex
20 85
123 21 49 117 1997 NOV [15] BIOCHEMISTRY-MOSCOW 62 (11): 1196-1201
Blackburn EH
The telomere and telomerase: Nucleic acid-protein complexes acting in a telomere homeostasis system. A review
3 28
124 0 0 121 1997 NOV [15] MOLECULAR BIOLOGY OF THE CELL 8: 1851-1851
Smith CD; McEachern MJ; Blackburn EH
Consequences of telomere mutations in Kluveromyces lactis
0 0
125 11 44 125 1998 FEB [15] CURRENT GENETICS 33 (2): 83-91
Cohn M; McEachern MJ; Blackburn EH
Telomeric sequence diversity within the genus Saccharomyces
5 24
126 13 38 126 1998 FEB 16 EMBO JOURNAL 17 (4): 1152-1160
Wang H; Gilley D; Blackburn EH
A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase
6 23
127 4 13 139 1998 APR [15] TRENDS IN BIOCHEMICAL SCIENCES 23 (4): 126-126
Hiraoka Y; Henderson E; Blackburn EH
Not so peculiar: Fission yeast telomere repeats
1 13
128 3 24 135 1998 MAY 12 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (10): 5607-5610
Frenck RW; Blackburn EH; Shannon KM
The rate of telomere sequence loss in human leukocytes varies with age
4 124
129 9 51 129 1998 MAY [15] MOLECULAR AND CELLULAR BIOLOGY 18 (5): 3021-3033
Gallagher RC; Blackburn EH
A promoter region mutation affecting replication of the Tetrahymena ribosomal DNA minichromosome
0 12
130 18 41 137 1998 [JUN 30] TELOMERES AND TELOMERASE 211: 2-15
Blackburn EH; Bhattacharyya A; Gilley D; Kirk K; Krauskopf A; et al.
The telomere and telomerase: how do they interact?
0 0
# LCR NCR Node / Date / Journal / Author LCS GCS
131 1 8 138 1998 [JUN 30] TELOMERES AND TELOMERASE 211: 139-144
Kipling D; Harley CB; Cech TR; Shall S; Lansdorp PM; et al.
Human ageing and telomeres - Discussion
0 0
132 18 67 128 1998 JUL 17 JOURNAL OF MOLECULAR BIOLOGY 280 (3): 327-344
Cohen P; Blackburn EH
Two types of telomeric chromatin in Tetrahymena thermophila
3 14
133 21 44 130 1998 SEP [15] MOLECULAR AND CELLULAR BIOLOGY 18 (9): 4961-4970
Fulton TB; Blackburn EH
Identification of Kluyveromyces lactis telomerase: Discontinuous synthesis along the 30-nucleotide-long templating domain
14 30
134 7 28 136 1998 OCT 13 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (21): 12486-12491
Krauskopf A; Blackburn EH
Rap1 protein regulates telomere turnover in yeast
15 39
135 15 50 127 1998 OCT 15 GENES & DEVELOPMENT 12 (20): 3286-3300
Roy J; Fulton TB; Blackburn EH
Specific telomerase RNA residues distant from the template are essential for telomerase function
18 53
136 0 0 131 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9: 68A-68A
Tzfati Y; Roy J; Blackburn EH
Cloning and analyses of telomerase RNA genes from related Kluyveromyces species
0 0
137 0 0 132 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9: 68A-68A
Fulton TB; Blackburn EH
Discontinuous telomere repeat synthesis by telomerase from the budding yeast Kluyveromyces lactis.
0 0
138 0 0 133 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9: 68A-68A
Gilley D; Blackburn EH
The telomerase RNA pseudoknot is required for the assembly of the catalytic component
0 0
139 0 0 134 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9: 263A-263A
Prescott J; Blackburn EH
Replication of telomeric DNA by telomerase in Saccharomyces cerevisiae
0 0
140 13 54 144 1999 MAR 30 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (7): 3616-3621
Cano MIN; Dungan JM; Agabian N; Blackburn EH
Telomerase in kinetoplastid parasitic protozoa
1 24
# LCR NCR Node / Date / Journal / Author LCS GCS
141 4 43 145 1999 MAR 30 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (7): 3723-3728
Zhu JY; Wang H; Bishop JM; Blackburn EH
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
14 214
142 13 43 141 1999 APR 19 JOURNAL OF CELL BIOLOGY 145 (2): 203-214
Smith CD; Blackburn EH
Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast
17 40
143 8 34 146 1999 JUN 8 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (12): 6621-6625
Gilley D; Blackburn EH
The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein
7 50
144 10 59 140 1999 JUN [15] CURRENT OPINION IN GENETICS & DEVELOPMENT 9 (3): 368-373
Prescott JC; Blackburn EH
Telomerase: Dr Jekyll or Mr Hyde?
0 23
145 22 30 143 1999 OCT-NOV [OCT 15] MOUNT SINAI JOURNAL OF MEDICINE 66 (5-6): 292-300
Blackburn EH
The telomere and telomerase: How do they interact?
2 14
146 4 41 147 1999 OCT 26 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (22): 12454-12458
Hsu HL; Gilley D; Blackburn EH; Chen DJ
Ku is associated with the telomere in mammals
4 179
147 0 0 142 1999 NOV [15] MOLECULAR BIOLOGY OF THE CELL 10: 350A-350A
Blackburn EH
New ways of thinking about telomeres and telomerase
0 0
148 14 45 153 2000 APR [15] MOLECULAR AND CELLULAR BIOLOGY 20 (8): 2941-2948
Prescott JC; Blackburn EH
Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres
13 34
149 7 26 157 2000 MAY 5 SCIENCE 288 (5467): 863-867
Tzfati Y; Fulton TB; Roy J; Blackburn EH
Template boundary in a yeast telomerase specified by RNA structure
10 47
150 0 0 151 2000 MAY 11 FASEB JOURNAL 14 (8): A1310-A1310
Blackburn EH
Telomeres and their cellular growth effects
0 0
# LCR NCR Node / Date / Journal / Author LCS GCS
151 24 61 150 2000 JUN 15 EMBO JOURNAL 19 (12): 3119-3131
Ware TL; Wang H; Blackburn EH
Three telomerases with completely non-telomeric template replacements are catalytically active
5 28
152 34 178 148 2000 [JUN 30] ANNUAL REVIEW OF GENETICS 34: 331-358
McEachern MJ; Krauskopf A; Blackburn EH
Telomeres and their control
6 272
153 29 93 149 2000 [JUN 30] COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 65: 253-263
Blackburn EH; Chan S; Chang J; Fulton TB; Krauskopf A; et al.
Molecular manifestations and molecular determinants of telomere capping
2 11
154 15 32 152 2000 [JUN 30] METHODS IN CELL BIOLOGY, VOL 62 62: 417-+
Blackburn EH; Gilley D; Ware T; Bhattacharyya A; Kirk K; et al.
Studying the telomerase RNA in Tetrahymena
0 3
155 13 39 156 2000 OCT 10 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97 (21): 11409-11414
McEachern MJ; Iyer S; Fulton TB; Blackburn EH
Telomere fusions caused by mutating the terminal region of telomeric DNA
4 36
156 16 52 155 2000 OCT [15] NATURE STRUCTURAL BIOLOGY 7 (10): 847-850
Blackburn EH
The end of the (DNA) line
11 59
157 12 48 154 2000 NOV 2 NATURE 408 (6808): 53-56
Blackburn EH
Telomere states and cell fates
15 294
158 12 37 160 2001 JUL 3 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98 (14): 7982-7987
Kim MM; Rivera MA; Botchkina IL; Shalaby R; Thor AD; et al.
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
11 62
159 14 48 159 2001 AUG 21 CURRENT BIOLOGY 11 (16): 1240-1250
Chan SWL; Chang J; Prescott J; Blackburn EH
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases
7 53
160 25 108 158 2001 SEP 21 CELL 106 (6): 661-673
Blackburn EH
Switching and signaling at the telomere
8 429
# LCR NCR Node / Date / Journal / Author LCS GCS
161 8 56 164 2002 JAN 11 JOURNAL OF BIOLOGICAL CHEMISTRY 277 (2): 896-906
Cano MIN; Blake JJ; Blackburn EH; Agabian N
A Trypanosoma brucei protein complex that binds G-overhangs and co-purifies with telomerase activity.
0 3
162 22 59 163 2002 JAN [15] GENETICS 160 (1): 63-73
McEachern MJ; Underwood DH; Blackburn EH
Dynamics of telomeric DNA turnover in yeast
2 16
163 22 110 166 2002 JAN 21 ONCOGENE 21 (4): 553-563
Chan SWL; Blackburn EH
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin
1 86
164 2 38 167 2002 JUL 9 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 (14): 9316-9321
Nautiyal S; DeRisi JL; Blackburn EH
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
3 29
165 5 38 162 2002 NOV 1 GENES & DEVELOPMENT 16 (21): 2800-2812
Seto AG; Livengood AJ; Tzfati Y; Blackburn EH; Cech TR
A bulged stem tethers Est1p to telomerase RNA in budding yeast
5 36
166 0 0 165 2002 NOV [15] MOLECULAR BIOLOGY OF THE CELL 13: 434A-434A
Botchkina I; Kurfurst R; Bonte F; Blackburn EH
Modulation by telomerase of cellular responses to damage in normal human primary skin keratinocytes and fibroblasts
0 0
167 0 0 161 2002 DEC [15] BIOTECHNOLOGY LAW REPORT 21 (6): 558-567
Kass LR; Blackburn EH; Carter SL; Dresser RS; Foster DW; et al.
Regulatory affairs - Bioethics council calls for ban on reproductive human cloning
0 0
168 5 24 168 2002 DEC 24 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 (26): 16998-17003
Comolli LR; Smirnov I; Xu LF; Blackburn EH; James TL
A molecular switch underlies a human telomerase disease
5 41
169 4 78 173 2003 FEB [15] MOLECULAR BIOLOGY OF THE CELL 14 (2): 556-570
Smith CD; Smith DL; DeRisi JL; Blackburn EH
Telomeric protein distribution and remodeling through the cell cycle in Saccharomyces cerevisiae
4 33
170 8 40 170 2003 MAY 1 GENES & DEVELOPMENT 17 (9): 1078-1083
Ly H; Xu LF; Rivera MA; Parslow TG; Blackburn EH
A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase
7 28
# LCR NCR Node / Date / Journal / Author LCS GCS
171 7 48 174 2003 MAY [15] MOLECULAR CELL 11 (5): 1379-1387
Chan SWL; Blackburn EH
Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining
5 55
172 22 38 171 2003 JUL 15 GENES & DEVELOPMENT 17 (14): 1779-1788
Tzfati Y; Knight Z; Roy R; Blackburn EH
A novel pseudoknot element is essential for the action of a yeast telomerase
4 22
173 12 58 169 2003 AUG 15 EXPERIMENTAL CELL RESEARCH 288 (2): 277-287
Kim M; Xu LF; Blackburn EH
Catalytically active human telomerase mutants with allele-specific biological properties
4 10
174 7 30 172 2003 OCT [15] MOLECULAR AND CELLULAR BIOLOGY 23 (19): 6849-6856
Ly H; Blackburn EH; Parslow TG
Comprehensive structure-function analysis of the core domain of human telomerase RNA
4 31
175 9 24 175 2003 NOV [15] RNA-A PUBLICATION OF THE RNA SOCIETY 9 (11): 1323-1332
Seto AG; Umansky K; Tzfati Y; Zaug AJ; Blackburn EH; et al.
A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity
2 13
176 34 89 188 2004 JAN 29 PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES 359 (1441): 109-121
Chan SRWL; Blackburn EH
Telomeres and telomerase
0 36
177 6 57 180 2004 FEB 15 GENES & DEVELOPMENT 18 (4): 387-396
Lin J; Blackburn EH
Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA
3 17
178 0 0 183 2004 MAR [15] JOURNAL OF INVESTIGATIVE DERMATOLOGY 122 (3): A158-A158
Bagheri S; Li S; Nosrati M; Fong S; LaPosa RR; et al.
Ribozyme-mediated inhibition of telomerase activity suppresses in vitro & in vivo growth and metastatic potential of murine melanoma cells
0 0
179 15 50 186 2004 APR [15] MOLECULAR BIOLOGY OF THE CELL 15 (4): 1623-1634
Lin J; Smith DL; Blackburn EH
Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response
3 9
180 1 41 184 2004 MAY [15] MOLECULAR AND CELLULAR BIOLOGY 24 (9): 4019-4031
Makovets S; Herskowitz I; Blackburn EH
Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions
0 8
# LCR NCR Node / Date / Journal / Author LCS GCS
181 0 0 176 2004 [JUN 30] BREAST CANCER RESEARCH AND TREATMENT 88: S2-S2
Li S; Xu L; Warner CL; Rosenberg J; Botchkina IL; et al.
Interventions in telomerase acton in human cancer cells
0 0
182 0 0 179 2004 [JUN 30] ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 44 (3): 189-189
Blackburn EH; Li S; Chan S; Kim M; Smith C; et al.
Modulation of telomere stability and DNA damage responses by telomerase
0 0
183 10 43 177 2004 JUL 15 CANCER RESEARCH 64 (14): 4833-4840
Li S; Rosenberg JE; Donjacour AA; Botchkina IL; Hom YK; et al.
Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA
6 35
184 0 1 187 2004 JUL 15 NEW ENGLAND JOURNAL OF MEDICINE 351 (3): 299-300
Blackburn EH
Bioethics, science, and politics - Reply
0 0
185 4 38 178 2004 AUG 1 CLINICAL CANCER RESEARCH 10 (15): 4983-4990
Nosrati M; Li S; Bagheri S; Ginzinger D; Blackburn EH; et al.
Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA
5 10
186 0 1 189 2004 AUG 31 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (35): 13100-13100
Nautiyal S; DeRisi JL; Blackburn EH
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae (vol 99, pg 9316, 2002)
0 0
187 16 37 190 2004 OCT 12 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (41): 14713-14718
Lin J; Ly H; Hussain A; Abraham M; Pearl S; et al.
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein
3 20
188 8 43 182 2004 DEC 6 JOURNAL OF CELL BIOLOGY 167 (5): 819-830
Xu LF; Blackburn EH
Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules
2 8
189 3 27 191 2004 DEC 7 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (49): 17312-17315
Epel ES; Blackburn EH; Lin J; Dhabhar FS; Adler NE; et al.
Accelerated telomere shortening in response to life stress
2 61
190 6 51 185 2004 DEC [15] MOLECULAR AND CELLULAR BIOLOGY 24 (24): 10857-10867
Levy DL; Blackburn EH
Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length
3 11
# LCR NCR Node / Date / Journal / Author LCS GCS
191 29 74 181 2004 DEC 17 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (51): 53770-53781
Rivera MA; Blackburn EH
Processive utilization of the human telomerase template - Lack of a requirement for template switching
0 8
192 13 26 193 2005 FEB 7 FEBS LETTERS 579 (4): 859-862
Blackburn EH
Telomeres and telomerase: their mechanisms of action and the effects of altering their functions
0 36
193 13 68 194 2005 JUN 24 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (25): 23709-23717
Li S; Crothers J; Haqq CM; Blackburn EH
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA
4 19
194 2 27 192 2005 AUG 15 BLOOD 106 (4): 1246-1252
Ly H; Schertzer M; Jastaniah W; Davis J; Yong SL; et al.
Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita
0 4
195 6 11 196 2005 AUG 18 NATURE 436 (7053): 922-923
Blackburn EH
Cell biology - Shaggy mouse tales
0 1
196 1 1 197 2005 SEP 6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (36): 12996-12996
Lin J; Ly H; Hussain A; Abraham M; Pearl S; et al.
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein (vol 101, pg 14713, 2004)
0 0
197 8 10 195 2005 SEP [15] MOLECULAR CANCER RESEARCH 3 (9): 477-482
Blackburn EH
Telomerase and cancer - Kirk A. Landon - AACR prize for basic cancer research lecture
0 1
198 0 0 199 2006 MAR 7 FASEB JOURNAL 20 (5): A890-A890
Blackburn EH
Telomeres and senescence
0 0
199 0 0 200 2006 APR [15] GASTROENTEROLOGY 130 (4): A128-A128
Doebele M; von Werder A; Fulda C; Heeg S; Goessel G; et al.
Inhibition of telomerase by mutant template telomerase RNA and anti-telomerase siRNA induces ALT in immortalized human esophageal epithelial cells
0 0
200 4 39 202 2006 APR [15] PSYCHONEUROENDOCRINOLOGY 31 (3): 277-287
Epel ES; Lin J; Wilhelm FH; Wolkowitz OM; Cawthon R; et al.
Cell aging in relation to stress arousal and cardiovascular disease risk factors
0 0

#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
101	10	37	90 1994 JUN [15] GENETICS 137 (2): 455-466 KAPLER GM; ORIAS E; BLACKBURN EH TETRAHYMENA-THERMOPHILA MUTANTS DEFECTIVE IN THE DEVELOPMENTALLY PROGRAMMED MATURATION AND MAINTENANCE OF THE RDNA MINICHROMOSOME	3	14
102	7	50	88 1994 DEC 1 EMBO JOURNAL 13 (23): 5721-5731 BHATTACHARYYA A; BLACKBURN EH ARCHITECTURE OF TELOMERASE RNA	8	46
103	19	66	103 1995 JAN 1 GENES & DEVELOPMENT 9 (1): 59-71 KIRK KE; BLACKBURN EH AN UNUSUAL SEQUENCE ARRANGEMENT IN THE TELOMERES OF THE GERM-LINE MICRONUCLEUS IN TETRAHYMENA-THERMOPHILA	8	19
104	0	0	105 1995 JAN 5 JOURNAL OF CELLULAR BIOCHEMISTRY : 209-209 GILLEY D; LEE MS; BLACKBURN EH TEMPLATE FUNCTION IN THE TELOMERASE RNA OF TETRAHYMENA	0	0
105	16	30	106 1995 JAN-FEB [JAN 15] JOURNAL OF EUKARYOTIC MICROBIOLOGY 42 (1): 32-43 ROMERO DP; BLACKBURN EH CIRCULAR RDNA REPLICONS PERSIST IN TETRAHYMENA-THERMOPHILA TRANSFORMANTS SYNTHESIZING GGGGTC TELOMERIC REPEATS	10	18
106	7	32	109 1995 MAY 11 NUCLEIC ACIDS RESEARCH 23 (9): 1561-1569 PAN WJ; BLACKBURN EH TANDEM REPEATS OF THE 5' NONTRANSCRIBED SPACER OF TETRAHYMENA RDNA FUNCTION AS HIGH COPY NUMBER AUTONOMOUS REPLICONS IN THE MACRONUCLEUS BUT DO NOT PREVENT RIBOSOMAL-RNA GENE DOSAGE REGULATION	1	10
107	9	33	107 1995 JUN [15] MOLECULAR AND CELLULAR BIOLOGY 15 (6): 3372-3381 PAN WJ; GALLAGHER RC; BLACKBURN EH REPLICATION OF AN RIBOSOMAL-RNA GENE ORIGIN PLASMID IN THE TETRAHYMENA-THERMOPHILA MACRONUCLEUS IS PREVENTED BY TRANSCRIPTION THROUGH THE ORIGIN FROM AN RNA-POLYMERASE-I PROMOTER	2	19
108	0	0	111 1995 [JUN 30] TELOMERES BLACKBURN EH; GREIDER CW Telomeres (Monograph 29), edited by Elizabeth H. Blackburn and Carol W. Greider.	12	159
109	14	30	110 1995 JUL 21 SCIENCE 269 (5222): 396-400 COHN M; BLACKBURN EH TELOMERASE IN YEAST	25	170
110	12	43	108 1995 AUG 3 NATURE 376 (6539): 403-409 MCEACHERN MJ; BLACKBURN EH RUNAWAY TELOMERE ELONGATION CAUSED BY TELOMERASE RNA GENE-MUTATIONS	33	241
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
111	15	37	104 1995 SEP 15 GENES & DEVELOPMENT 9 (18): 2214-2226 GILLEY D; LEE MS; BLACKBURN EH ALTERING SPECIFIC TELOMERASE RNA TEMPLATE RESIDUES AFFECTS ACTIVE-SITE FUNCTION	26	86
112	12	49	113 1996 JAN [15] MOLECULAR AND CELLULAR BIOLOGY 16 (1): 53-65 Strahl C; Blackburn EH Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines	9	231
113	15	35	114 1996 JAN [15] MOLECULAR AND CELLULAR BIOLOGY 16 (1): 66-75 Gilley D; Blackburn EH Specific RNA residue interactions required for enzymatic functions of Tetrahymenatelomerase	20	68
114	3	4	116 1996 FEB [15] SCIENTIFIC AMERICAN 274 (2): 92-97 Greider CW; Blackburn EH Telomeres, telomerase and cancer	1	103
115	11	56	112 1996 JUL 15 GENES & DEVELOPMENT 10 (14): 1822-1834 McEachern MJ; Blackburn EH Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase	23	159
116	3	19	115 1996 SEP 26 NATURE 383 (6598): 354-357 Krauskopf A; Blackburn EH Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats	30	116
117	16	49	119 1997 FEB 15 GENES & DEVELOPMENT 11 (4): 528-540 Prescott J; Blackburn EH Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro	37	99
118	13	50	118 1997 FEB 17 EMBO JOURNAL 16 (4): 866-879 Wang H; Blackburn EH De nova telomere addition by Tetrahymena telomerase in vitro	4	58
119	6	29	124 1997 MAR 7 SCIENCE 275 (5305): 1478-1481 Kirk KE; Harmon BP; Reichardt IK; Sedat JW; Blackburn EH Block in anaphase chromosome separation caused by a telomerase template mutation	19	157
120	3	29	122 1997 APR 1 NUCLEIC ACIDS RESEARCH 25 (7): 1426-1431 Bhattacharyya A; Blackburn EH Aspergillus nidulans maintains short telomeres throughout development	0	14
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
121	8	29	123 1997 APR 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (7): 2823-2827 Bhattacharyya A; Blackburn EH A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains	9	39
122	11	66	120 1997 NOV 1 GENES & DEVELOPMENT 11 (21): 2790-2800 Prescott J; Blackburn EH Functionally interacting telomerase RNAs in the yeast telomerase complex	20	85
123	21	49	117 1997 NOV [15] BIOCHEMISTRY-MOSCOW 62 (11): 1196-1201 Blackburn EH The telomere and telomerase: Nucleic acid-protein complexes acting in a telomere homeostasis system. A review	3	28
124	0	0	121 1997 NOV [15] MOLECULAR BIOLOGY OF THE CELL 8: 1851-1851 Smith CD; McEachern MJ; Blackburn EH Consequences of telomere mutations in Kluveromyces lactis	0	0
125	11	44	125 1998 FEB [15] CURRENT GENETICS 33 (2): 83-91 Cohn M; McEachern MJ; Blackburn EH Telomeric sequence diversity within the genus Saccharomyces	5	24
126	13	38	126 1998 FEB 16 EMBO JOURNAL 17 (4): 1152-1160 Wang H; Gilley D; Blackburn EH A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase	6	23
127	4	13	139 1998 APR [15] TRENDS IN BIOCHEMICAL SCIENCES 23 (4): 126-126 Hiraoka Y; Henderson E; Blackburn EH Not so peculiar: Fission yeast telomere repeats	1	13
128	3	24	135 1998 MAY 12 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (10): 5607-5610 Frenck RW; Blackburn EH; Shannon KM The rate of telomere sequence loss in human leukocytes varies with age	4	124
129	9	51	129 1998 MAY [15] MOLECULAR AND CELLULAR BIOLOGY 18 (5): 3021-3033 Gallagher RC; Blackburn EH A promoter region mutation affecting replication of the Tetrahymena ribosomal DNA minichromosome	0	12
130	18	41	137 1998 [JUN 30] TELOMERES AND TELOMERASE 211: 2-15 Blackburn EH; Bhattacharyya A; Gilley D; Kirk K; Krauskopf A; et al. The telomere and telomerase: how do they interact?	0	0
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
131	1	8	138 1998 [JUN 30] TELOMERES AND TELOMERASE 211: 139-144 Kipling D; Harley CB; Cech TR; Shall S; Lansdorp PM; et al. Human ageing and telomeres - Discussion	0	0
132	18	67	128 1998 JUL 17 JOURNAL OF MOLECULAR BIOLOGY 280 (3): 327-344 Cohen P; Blackburn EH Two types of telomeric chromatin in Tetrahymena thermophila	3	14
133	21	44	130 1998 SEP [15] MOLECULAR AND CELLULAR BIOLOGY 18 (9): 4961-4970 Fulton TB; Blackburn EH Identification of Kluyveromyces lactis telomerase: Discontinuous synthesis along the 30-nucleotide-long templating domain	14	30
134	7	28	136 1998 OCT 13 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (21): 12486-12491 Krauskopf A; Blackburn EH Rap1 protein regulates telomere turnover in yeast	15	39
135	15	50	127 1998 OCT 15 GENES & DEVELOPMENT 12 (20): 3286-3300 Roy J; Fulton TB; Blackburn EH Specific telomerase RNA residues distant from the template are essential for telomerase function	18	53
136	0	0	131 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9: 68A-68A Tzfati Y; Roy J; Blackburn EH Cloning and analyses of telomerase RNA genes from related Kluyveromyces species	0	0
137	0	0	132 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9: 68A-68A Fulton TB; Blackburn EH Discontinuous telomere repeat synthesis by telomerase from the budding yeast Kluyveromyces lactis.	0	0
138	0	0	133 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9: 68A-68A Gilley D; Blackburn EH The telomerase RNA pseudoknot is required for the assembly of the catalytic component	0	0
139	0	0	134 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9: 263A-263A Prescott J; Blackburn EH Replication of telomeric DNA by telomerase in Saccharomyces cerevisiae	0	0
140	13	54	144 1999 MAR 30 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (7): 3616-3621 Cano MIN; Dungan JM; Agabian N; Blackburn EH Telomerase in kinetoplastid parasitic protozoa	1	24
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
141	4	43	145 1999 MAR 30 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (7): 3723-3728 Zhu JY; Wang H; Bishop JM; Blackburn EH Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening	14	214
142	13	43	141 1999 APR 19 JOURNAL OF CELL BIOLOGY 145 (2): 203-214 Smith CD; Blackburn EH Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast	17	40
143	8	34	146 1999 JUN 8 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (12): 6621-6625 Gilley D; Blackburn EH The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein	7	50
144	10	59	140 1999 JUN [15] CURRENT OPINION IN GENETICS & DEVELOPMENT 9 (3): 368-373 Prescott JC; Blackburn EH Telomerase: Dr Jekyll or Mr Hyde?	0	23
145	22	30	143 1999 OCT-NOV [OCT 15] MOUNT SINAI JOURNAL OF MEDICINE 66 (5-6): 292-300 Blackburn EH The telomere and telomerase: How do they interact?	2	14
146	4	41	147 1999 OCT 26 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (22): 12454-12458 Hsu HL; Gilley D; Blackburn EH; Chen DJ Ku is associated with the telomere in mammals	4	179
147	0	0	142 1999 NOV [15] MOLECULAR BIOLOGY OF THE CELL 10: 350A-350A Blackburn EH New ways of thinking about telomeres and telomerase	0	0
148	14	45	153 2000 APR [15] MOLECULAR AND CELLULAR BIOLOGY 20 (8): 2941-2948 Prescott JC; Blackburn EH Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres	13	34
149	7	26	157 2000 MAY 5 SCIENCE 288 (5467): 863-867 Tzfati Y; Fulton TB; Roy J; Blackburn EH Template boundary in a yeast telomerase specified by RNA structure	10	47
150	0	0	151 2000 MAY 11 FASEB JOURNAL 14 (8): A1310-A1310 Blackburn EH Telomeres and their cellular growth effects	0	0
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
151	24	61	150 2000 JUN 15 EMBO JOURNAL 19 (12): 3119-3131 Ware TL; Wang H; Blackburn EH Three telomerases with completely non-telomeric template replacements are catalytically active	5	28
152	34	178	148 2000 [JUN 30] ANNUAL REVIEW OF GENETICS 34: 331-358 McEachern MJ; Krauskopf A; Blackburn EH Telomeres and their control	6	272
153	29	93	149 2000 [JUN 30] COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 65: 253-263 Blackburn EH; Chan S; Chang J; Fulton TB; Krauskopf A; et al. Molecular manifestations and molecular determinants of telomere capping	2	11
154	15	32	152 2000 [JUN 30] METHODS IN CELL BIOLOGY, VOL 62 62: 417-+ Blackburn EH; Gilley D; Ware T; Bhattacharyya A; Kirk K; et al. Studying the telomerase RNA in Tetrahymena	0	3
155	13	39	156 2000 OCT 10 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97 (21): 11409-11414 McEachern MJ; Iyer S; Fulton TB; Blackburn EH Telomere fusions caused by mutating the terminal region of telomeric DNA	4	36
156	16	52	155 2000 OCT [15] NATURE STRUCTURAL BIOLOGY 7 (10): 847-850 Blackburn EH The end of the (DNA) line	11	59
157	12	48	154 2000 NOV 2 NATURE 408 (6808): 53-56 Blackburn EH Telomere states and cell fates	15	294
158	12	37	160 2001 JUL 3 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98 (14): 7982-7987 Kim MM; Rivera MA; Botchkina IL; Shalaby R; Thor AD; et al. A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation	11	62
159	14	48	159 2001 AUG 21 CURRENT BIOLOGY 11 (16): 1240-1250 Chan SWL; Chang J; Prescott J; Blackburn EH Altering telomere structure allows telomerase to act in yeast lacking ATM kinases	7	53
160	25	108	158 2001 SEP 21 CELL 106 (6): 661-673 Blackburn EH Switching and signaling at the telomere	8	429
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
161	8	56	164 2002 JAN 11 JOURNAL OF BIOLOGICAL CHEMISTRY 277 (2): 896-906 Cano MIN; Blake JJ; Blackburn EH; Agabian N A Trypanosoma brucei protein complex that binds G-overhangs and co-purifies with telomerase activity.	0	3
162	22	59	163 2002 JAN [15] GENETICS 160 (1): 63-73 McEachern MJ; Underwood DH; Blackburn EH Dynamics of telomeric DNA turnover in yeast	2	16
163	22	110	166 2002 JAN 21 ONCOGENE 21 (4): 553-563 Chan SWL; Blackburn EH New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin	1	86
164	2	38	167 2002 JUL 9 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 (14): 9316-9321 Nautiyal S; DeRisi JL; Blackburn EH The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae	3	29
165	5	38	162 2002 NOV 1 GENES & DEVELOPMENT 16 (21): 2800-2812 Seto AG; Livengood AJ; Tzfati Y; Blackburn EH; Cech TR A bulged stem tethers Est1p to telomerase RNA in budding yeast	5	36
166	0	0	165 2002 NOV [15] MOLECULAR BIOLOGY OF THE CELL 13: 434A-434A Botchkina I; Kurfurst R; Bonte F; Blackburn EH Modulation by telomerase of cellular responses to damage in normal human primary skin keratinocytes and fibroblasts	0	0
167	0	0	161 2002 DEC [15] BIOTECHNOLOGY LAW REPORT 21 (6): 558-567 Kass LR; Blackburn EH; Carter SL; Dresser RS; Foster DW; et al. Regulatory affairs - Bioethics council calls for ban on reproductive human cloning	0	0
168	5	24	168 2002 DEC 24 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 (26): 16998-17003 Comolli LR; Smirnov I; Xu LF; Blackburn EH; James TL A molecular switch underlies a human telomerase disease	5	41
169	4	78	173 2003 FEB [15] MOLECULAR BIOLOGY OF THE CELL 14 (2): 556-570 Smith CD; Smith DL; DeRisi JL; Blackburn EH Telomeric protein distribution and remodeling through the cell cycle in Saccharomyces cerevisiae	4	33
170	8	40	170 2003 MAY 1 GENES & DEVELOPMENT 17 (9): 1078-1083 Ly H; Xu LF; Rivera MA; Parslow TG; Blackburn EH A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase	7	28
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
171	7	48	174 2003 MAY [15] MOLECULAR CELL 11 (5): 1379-1387 Chan SWL; Blackburn EH Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining	5	55
172	22	38	171 2003 JUL 15 GENES & DEVELOPMENT 17 (14): 1779-1788 Tzfati Y; Knight Z; Roy R; Blackburn EH A novel pseudoknot element is essential for the action of a yeast telomerase	4	22
173	12	58	169 2003 AUG 15 EXPERIMENTAL CELL RESEARCH 288 (2): 277-287 Kim M; Xu LF; Blackburn EH Catalytically active human telomerase mutants with allele-specific biological properties	4	10
174	7	30	172 2003 OCT [15] MOLECULAR AND CELLULAR BIOLOGY 23 (19): 6849-6856 Ly H; Blackburn EH; Parslow TG Comprehensive structure-function analysis of the core domain of human telomerase RNA	4	31
175	9	24	175 2003 NOV [15] RNA-A PUBLICATION OF THE RNA SOCIETY 9 (11): 1323-1332 Seto AG; Umansky K; Tzfati Y; Zaug AJ; Blackburn EH; et al. A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity	2	13
176	34	89	188 2004 JAN 29 PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES 359 (1441): 109-121 Chan SRWL; Blackburn EH Telomeres and telomerase	0	36
177	6	57	180 2004 FEB 15 GENES & DEVELOPMENT 18 (4): 387-396 Lin J; Blackburn EH Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA	3	17
178	0	0	183 2004 MAR [15] JOURNAL OF INVESTIGATIVE DERMATOLOGY 122 (3): A158-A158 Bagheri S; Li S; Nosrati M; Fong S; LaPosa RR; et al. Ribozyme-mediated inhibition of telomerase activity suppresses in vitro & in vivo growth and metastatic potential of murine melanoma cells	0	0
179	15	50	186 2004 APR [15] MOLECULAR BIOLOGY OF THE CELL 15 (4): 1623-1634 Lin J; Smith DL; Blackburn EH Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response	3	9
180	1	41	184 2004 MAY [15] MOLECULAR AND CELLULAR BIOLOGY 24 (9): 4019-4031 Makovets S; Herskowitz I; Blackburn EH Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions	0	8
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
181	0	0	176 2004 [JUN 30] BREAST CANCER RESEARCH AND TREATMENT 88: S2-S2 Li S; Xu L; Warner CL; Rosenberg J; Botchkina IL; et al. Interventions in telomerase acton in human cancer cells	0	0
182	0	0	179 2004 [JUN 30] ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 44 (3): 189-189 Blackburn EH; Li S; Chan S; Kim M; Smith C; et al. Modulation of telomere stability and DNA damage responses by telomerase	0	0
183	10	43	177 2004 JUL 15 CANCER RESEARCH 64 (14): 4833-4840 Li S; Rosenberg JE; Donjacour AA; Botchkina IL; Hom YK; et al. Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA	6	35
184	0	1	187 2004 JUL 15 NEW ENGLAND JOURNAL OF MEDICINE 351 (3): 299-300 Blackburn EH Bioethics, science, and politics - Reply	0	0
185	4	38	178 2004 AUG 1 CLINICAL CANCER RESEARCH 10 (15): 4983-4990 Nosrati M; Li S; Bagheri S; Ginzinger D; Blackburn EH; et al. Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA	5	10
186	0	1	189 2004 AUG 31 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (35): 13100-13100 Nautiyal S; DeRisi JL; Blackburn EH The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae (vol 99, pg 9316, 2002)	0	0
187	16	37	190 2004 OCT 12 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (41): 14713-14718 Lin J; Ly H; Hussain A; Abraham M; Pearl S; et al. A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein	3	20
188	8	43	182 2004 DEC 6 JOURNAL OF CELL BIOLOGY 167 (5): 819-830 Xu LF; Blackburn EH Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules	2	8
189	3	27	191 2004 DEC 7 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (49): 17312-17315 Epel ES; Blackburn EH; Lin J; Dhabhar FS; Adler NE; et al. Accelerated telomere shortening in response to life stress	2	61
190	6	51	185 2004 DEC [15] MOLECULAR AND CELLULAR BIOLOGY 24 (24): 10857-10867 Levy DL; Blackburn EH Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length	3	11
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
191	29	74	181 2004 DEC 17 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (51): 53770-53781 Rivera MA; Blackburn EH Processive utilization of the human telomerase template - Lack of a requirement for template switching	0	8
192	13	26	193 2005 FEB 7 FEBS LETTERS 579 (4): 859-862 Blackburn EH Telomeres and telomerase: their mechanisms of action and the effects of altering their functions	0	36
193	13	68	194 2005 JUN 24 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (25): 23709-23717 Li S; Crothers J; Haqq CM; Blackburn EH Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA	4	19
194	2	27	192 2005 AUG 15 BLOOD 106 (4): 1246-1252 Ly H; Schertzer M; Jastaniah W; Davis J; Yong SL; et al. Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita	0	4
195	6	11	196 2005 AUG 18 NATURE 436 (7053): 922-923 Blackburn EH Cell biology - Shaggy mouse tales	0	1
196	1	1	197 2005 SEP 6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (36): 12996-12996 Lin J; Ly H; Hussain A; Abraham M; Pearl S; et al. A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein (vol 101, pg 14713, 2004)	0	0
197	8	10	195 2005 SEP [15] MOLECULAR CANCER RESEARCH 3 (9): 477-482 Blackburn EH Telomerase and cancer - Kirk A. Landon - AACR prize for basic cancer research lecture	0	1
198	0	0	199 2006 MAR 7 FASEB JOURNAL 20 (5): A890-A890 Blackburn EH Telomeres and senescence	0	0
199	0	0	200 2006 APR [15] GASTROENTEROLOGY 130 (4): A128-A128 Doebele M; von Werder A; Fulda C; Heeg S; Goessel G; et al. Inhibition of telomerase by mutant template telomerase RNA and anti-telomerase siRNA induces ALT in immortalized human esophageal epithelial cells	0	0
200	4	39	202 2006 APR [15] PSYCHONEUROENDOCRINOLOGY 31 (3): 277-287 Epel ES; Lin J; Wilhelm FH; Wolkowitz OM; Cawthon R; et al. Cell aging in relation to stress arousal and cardiovascular disease risk factors	0	0

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