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Ranked All-Publication list

Fri Sep 15 15:09:28 2006

Papers by EH Blackburn

Collection span: 1972 - 2006

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Sorted by LCS.

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# LCR NCR Node / Date / Journal / Author LCS GCS
1 8 35 26 1985 CELL 43 (2): 405-413
GREIDER CW; BLACKBURN EH
IDENTIFICATION OF A SPECIFIC TELOMERE TERMINAL TRANSFERASE-ACTIVITY IN TETRAHYMENA EXTRACTS
54 1087
2 8 54 64 1989 NATURE 337 (6205): 331-337
GREIDER CW; BLACKBURN EH
A TELOMERIC SEQUENCE IN THE RNA OF TETRAHYMENA TELOMERASE REQUIRED FOR TELOMERE REPEAT SYNTHESIS
54 704
3 17 48 71 1990 NATURE 344 (6262): 126-132
YU GL; BRADLEY JD; ATTARDI LD; BLACKBURN EH
INVIVO ALTERATION OF TELOMERE SEQUENCES AND SENESCENCE CAUSED BY MUTATED TETRAHYMENA-TELOMERASE RNAS
52 431
4 8 39 45 1987 CELL 51 (6): 887-898
GREIDER CW; BLACKBURN EH
THE TELOMERE TERMINAL TRANSFERASE OF TETRAHYMENA IS A RIBONUCLEOPROTEIN ENZYME WITH 2 KINDS OF PRIMER SPECIFICITY
39 421
5 0 34 9 1978 JOURNAL OF MOLECULAR BIOLOGY 120 (1): 33-53
BLACKBURN EH; GALL JG
TANDEMLY REPEATED SEQUENCE AT TERMINI OF EXTRACHROMOSOMAL RIBOSOMAL-RNA GENES IN TETRAHYMENA
38 322
6 16 49 119 1997 GENES & DEVELOPMENT 11 (4): 528-540
Prescott J; Blackburn EH
Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro
37 99
7 5 123 22 1984 ANNUAL REVIEW OF BIOCHEMISTRY 53: 163-194
BLACKBURN EH; SZOSTAK JW
THE MOLECULAR-STRUCTURE OF CENTROMERES AND TELOMERES
33 502
8 3 31 25 1984 NATURE 310 (5973): 154-157
SHAMPAY J; SZOSTAK JW; BLACKBURN EH
DNA-SEQUENCES OF TELOMERES MAINTAINED IN YEAST
33 269
9 12 43 108 1995 NATURE 376 (6539): 403-409
MCEACHERN MJ; BLACKBURN EH
RUNAWAY TELOMERE ELONGATION CAUSED BY TELOMERASE RNA GENE-MUTATIONS
33 241
10 10 39 73 1990 SCIENCE 247 (4942): 546-552
SHIPPENLENTZ D; BLACKBURN EH
FUNCTIONAL EVIDENCE FOR AN RNA TEMPLATE IN TELOMERASE
32 230
# LCR NCR Node / Date / Journal / Author LCS GCS
11 18 45 76 1991 CELL 67 (4): 823-832
YU GL; BLACKBURN EH
DEVELOPMENTALLY PROGRAMMED HEALING OF CHROMOSOMES BY TELOMERASE IN TETRAHYMENA
31 160
12 3 19 115 1996 NATURE 383 (6598): 354-357
Krauskopf A; Blackburn EH
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
30 116
13 15 37 104 1995 GENES & DEVELOPMENT 9 (18): 2214-2226
GILLEY D; LEE MS; BLACKBURN EH
ALTERING SPECIFIC TELOMERASE RNA TEMPLATE RESIDUES AFFECTS ACTIVE-SITE FUNCTION
26 86
14 14 30 110 1995 SCIENCE 269 (5222): 396-400
COHN M; BLACKBURN EH
TELOMERASE IN YEAST
25 170
15 2 39 17 1982 CELL 29 (1): 245-255
SZOSTAK JW; BLACKBURN EH
CLONING YEAST TELOMERES ON LINEAR PLASMID VECTORS
24 290
16 9 51 83 1993 CELL 73 (2): 347-360
LUNDBLAD V; BLACKBURN EH
AN ALTERNATIVE PATHWAY FOR YEAST TELOMERE MAINTENANCE RESCUES EST1-SENESCENCE
23 435
17 11 56 112 1996 GENES & DEVELOPMENT 10 (14): 1822-1834
McEachern MJ; Blackburn EH
Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase
23 159
18 13 33 44 1987 CELL 50 (3): 477-483
LARSON DD; SPANGLER EA; BLACKBURN EH
DYNAMICS OF TELOMERE LENGTH VARIATION IN TETRAHYMENA THERMOPHILA
22 97
19 6 22 56 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85 (2): 534-538
SHAMPAY J; BLACKBURN EH
GENERATION OF TELOMERE-LENGTH HETEROGENEITY IN SACCHAROMYCES-CEREVISIAE
21 108
20 11 65 75 1991 CELL 67 (2): 343-353
ROMERO DP; BLACKBURN EH
A CONSERVED SECONDARY STRUCTURE FOR TELOMERASE RNA
21 159
# LCR NCR Node / Date / Journal / Author LCS GCS
21 15 72 79 1991 NATURE 350 (6319): 569-573
BLACKBURN EH
STRUCTURE AND FUNCTION OF TELOMERES
20 1530
22 15 35 114 1996 MOLECULAR AND CELLULAR BIOLOGY 16 (1): 66-75
Gilley D; Blackburn EH
Specific RNA residue interactions required for enzymatic functions of Tetrahymenatelomerase
20 68
23 11 66 120 1997 GENES & DEVELOPMENT 11 (21): 2790-2800
Prescott J; Blackburn EH
Functionally interacting telomerase RNAs in the yeast telomerase complex
20 85
24 0 0 24 1984 CELL 37 (1): 7-8
BLACKBURN EH
TELOMERES - DO THE ENDS JUSTIFY THE MEANS
19 100
25 15 31 81 1992 ANNUAL REVIEW OF BIOCHEMISTRY 61: 113-129
BLACKBURN EH
TELOMERASES
19 444
26 6 29 124 1997 SCIENCE 275 (5305): 1478-1481
Kirk KE; Harmon BP; Reichardt IK; Sedat JW; Blackburn EH
Block in anaphase chromosome separation caused by a telomerase template mutation
19 157
27 12 22 86 1993 MOLECULAR AND CELLULAR BIOLOGY 13 (10): 6586-6599
LEE MS; BLACKBURN EH
SEQUENCE-SPECIFIC DNA PRIMER EFFECTS ON TELOMERASE POLYMERIZATION ACTIVITY
18 71
28 7 21 87 1994 CELL 77 (5): 621-623
BLACKBURN EH
TELOMERES - NO END IN SIGHT
18 200
29 15 50 127 1998 GENES & DEVELOPMENT 12 (20): 3286-3300
Roy J; Fulton TB; Blackburn EH
Specific telomerase RNA residues distant from the template are essential for telomerase function
18 53
30 2 23 11 1981 CELL 23 (2): 459-466
PAN WC; BLACKBURN EH
SINGLE EXTRACHROMOSOMAL RIBOSOMAL-RNA GENE COPIES ARE SYNTHESIZED DURING AMPLIFICATION OF THE RDNA IN TETRAHYMENA
17 62
# LCR NCR Node / Date / Journal / Author LCS GCS
31 7 15 63 1989 MOLECULAR AND CELLULAR BIOLOGY 9 (6): 2761-2764
SHIPPENLENTZ D; BLACKBURN EH
TELOMERE TERMINAL TRANSFERASE-ACTIVITY FROM EUPLOTES-CRASSUS ADDS LARGE NUMBERS OF TTTTGGGG REPEATS ONTO TELOMERIC PRIMERS
17 95
32 13 43 141 1999 JOURNAL OF CELL BIOLOGY 145 (2): 203-214
Smith CD; Blackburn EH
Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast
17 40
33 2 36 12 1981 CELL 24 (2): 313-320
KATZEN AL; CANN GM; BLACKBURN EH
SEQUENCE-SPECIFIC FRAGMENTATION OF MACRONUCLEAR DNA IN A HOLOTRICHOUS CILIATE
15 70
34 9 46 34 1986 CELL 47 (2): 229-240
LARSON DD; BLACKBURN EH; YAEGER PC; ORIAS E
CONTROL OF RDNA REPLICATION IN TETRAHYMENA INVOLVES A CIS-ACTING UPSTREAM REPEAT OF A PROMOTER ELEMENT
15 104
35 7 28 136 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (21): 12486-12491
Krauskopf A; Blackburn EH
Rap1 protein regulates telomere turnover in yeast
15 39
36 12 48 154 2000 NATURE 408 (6808): 53-56
Blackburn EH
Telomere states and cell fates
15 294
37 4 33 16 1982 CELL 28 (3): 595-604
PAN WC; ORIAS E; FLACKS M; BLACKBURN EH
ALLELE-SPECIFIC, SELECTIVE AMPLIFICATION OF A RIBOSOMAL-RNA GENE IN TETRAHYMENA THERMOPHILA
14 56
38 4 50 30 1985 NUCLEIC ACIDS RESEARCH 13 (7): 2661-2680
CHALLONER PB; AMIN AA; PEARLMAN RE; BLACKBURN EH
CONSERVED ARRANGEMENTS OF REPEATED DNA-SEQUENCES IN NONTRANSCRIBED SPACERS OF CILIATE RIBOSOMAL-RNA GENES - EVIDENCE FOR MOLECULAR COEVOLUTION
14 46
39 21 44 130 1998 MOLECULAR AND CELLULAR BIOLOGY 18 (9): 4961-4970
Fulton TB; Blackburn EH
Identification of Kluyveromyces lactis telomerase: Discontinuous synthesis along the 30-nucleotide-long templating domain
14 30
40 4 43 145 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (7): 3723-3728
Zhu JY; Wang H; Bishop JM; Blackburn EH
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
14 214
# LCR NCR Node / Date / Journal / Author LCS GCS
41 11 37 102 1994 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91 (8): 3453-3457
MCEACHERN MJ; BLACKBURN EH
A CONSERVED SEQUENCE MOTIF WITHIN THE EXCEPTIONALLY DIVERSE TELOMERIC SEQUENCES OF BUDDING YEASTS
13 58
42 14 45 153 2000 MOLECULAR AND CELLULAR BIOLOGY 20 (8): 2941-2948
Prescott JC; Blackburn EH
Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres
13 34
43 2 31 15 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78 (4): 2263-2267
BLACKBURN EH; CHIOU SS
NON-NUCLEOSOMAL PACKAGING OF A TANDEMLY REPEATED DNA-SEQUENCE AT TERMINI OF EXTRACHROMOSOMAL DNA CODING FOR RIBOSOMAL-RNA IN TETRAHYMENA
12 67
44 8 42 46 1987 CELL 51 (6): 899-908
HENDERSON E; HARDIN CC; WALK SK; TINOCO I; BLACKBURN EH
TELOMERIC DNA OLIGONUCLEOTIDES FORM NOVEL INTRAMOLECULAR STRUCTURES CONTAINING GUANINE GUANINE BASE-PAIRS
12 342
45 0 0 111 1995 TELOMERES
BLACKBURN EH; GREIDER CW
Telomeres (Monograph 29), edited by Elizabeth H. Blackburn and Carol W. Greider.
12 159
46 4 32 23 1984 CELL 36 (2): 447-457
BLACKBURN EH; CHALLONER PB
IDENTIFICATION OF A TELOMERIC DNA-SEQUENCE IN TRYPANOSOMA-BRUCEI
11 128
47 2 21 31 1985 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82 (9): 2844-2846
BRUNS PJ; KATZEN AL; MARTIN L; BLACKBURN EH
A DRUG-RESISTANT MUTATION IN THE RIBOSOMAL DNA OF TETRAHYMENA
11 48
48 10 25 61 1989 MOLECULAR AND CELLULAR BIOLOGY 9 (1): 345-348
HENDERSON ER; BLACKBURN EH
AN OVERHANGING 3' TERMINUS IS A CONSERVED FEATURE OF TELOMERES
11 193
49 9 26 66 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86 (21): 8487-8491
YU GL; BLACKBURN EH
TRANSFORMATION OF TETRAHYMENA-THERMOPHILA WITH A MUTATED CIRCULAR RIBOSOMAL DNA PLASMA VECTOR
11 34
50 9 16 84 1993 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 58: 707-718
LEE MS; GALLAGHER RC; BRADLEY J; BLACKBURN EH
IN-VIVO AND IN-VITRO STUDIES OF TELOMERES AND TELOMERASE
11 28
# LCR NCR Node / Date / Journal / Author LCS GCS
51 16 52 155 2000 NATURE STRUCTURAL BIOLOGY 7 (10): 847-850
Blackburn EH
The end of the (DNA) line
11 59
52 12 37 160 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98 (14): 7982-7987
Kim MM; Rivera MA; Botchkina IL; Shalaby R; Thor AD; et al.
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
11 62
53 9 54 27 1985 CELL 43 (3): 747-758
CHERRY JM; BLACKBURN EH
THE INTERNALLY LOCATED TELOMERIC SEQUENCES IN THE GERM-LINE CHROMOSOMES OF TETRAHYMENA ARE AT THE ENDS OF TRANSPOSON-LIKE ELEMENTS
10 73
54 3 42 29 1985 MOLECULAR AND CELLULAR BIOLOGY 5 (8): 2039-2050
HOWARD EA; BLACKBURN EH
REPRODUCIBLE AND VARIABLE GENOMIC REARRANGEMENTS OCCUR IN THE DEVELOPING SOMATIC NUCLEUS OF THE CILIATE TETRAHYMENA-THERMOPHILA
10 54
55 8 42 55 1988 NUCLEIC ACIDS RESEARCH 16 (12): 5569-5585
SPANGLER EA; RYAN T; BLACKBURN EH
DEVELOPMENTALLY REGULATED TELOMERE ADDITION IN TETRAHYMENA-THERMOPHILA
10 21
56 16 30 106 1995 JOURNAL OF EUKARYOTIC MICROBIOLOGY 42 (1): 32-43
ROMERO DP; BLACKBURN EH
CIRCULAR RDNA REPLICONS PERSIST IN TETRAHYMENA-THERMOPHILA TRANSFORMANTS SYNTHESIZING GGGGTC TELOMERIC REPEATS
10 18
57 7 26 157 2000 SCIENCE 288 (5467): 863-867
Tzfati Y; Fulton TB; Roy J; Blackburn EH
Template boundary in a yeast telomerase specified by RNA structure
10 47
58 2 42 28 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260 (10): 6334-6340
SPANGLER EA; BLACKBURN EH
THE NUCLEOTIDE-SEQUENCE OF THE 17-S RIBOSOMAL-RNA GENE OF TETRAHYMENA-THERMOPHILA AND THE IDENTIFICATION OF POINT MUTATIONS RESULTING IN RESISTANCE TO THE ANTIBIOTICS PAROMOMYCIN AND HYGROMYCIN
9 140
59 7 42 36 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261 (1): 363-369
BUDARF ML; BLACKBURN EH
CHROMATIN STRUCTURE OF THE TELOMERIC REGION AND 3'-NONTRANSCRIBED SPACER OF TETRAHYMENA RIBOSOMAL-RNA GENES
9 47
60 5 34 54 1988 MOLECULAR AND CELLULAR BIOLOGY 8 (1): 251-258
FORNEY JD; BLACKBURN EH
DEVELOPMENTALLY CONTROLLED TELOMERE ADDITION IN WILD-TYPE AND MUTANT PARAMECIA
9 88
# LCR NCR Node / Date / Journal / Author LCS GCS
61 15 26 59 1989 GENOME 31 (2): 553-560
BLACKBURN EH; GREIDER CW; HENDERSON E; LEE MS; SHAMPAY J; et al.
RECOGNITION AND ELONGATION OF TELOMERES BY TELOMERASE
9 38
62 12 49 113 1996 MOLECULAR AND CELLULAR BIOLOGY 16 (1): 53-65
Strahl C; Blackburn EH
Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines
9 231
63 8 29 123 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (7): 2823-2827
Bhattacharyya A; Blackburn EH
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains
9 39
64 13 77 33 1986 ANNUAL REVIEW OF GENETICS 20: 501-521
BLACKBURN EH; KARRER KM
GENOMIC REORGANIZATION IN CILIATED PROTOZOANS
8 61
65 12 31 43 1986 NUCLEIC ACIDS RESEARCH 14 (15): 6299-6311
CHALLONER PB; BLACKBURN EH
CONSERVATION OF SEQUENCES ADJACENT TO THE TELOMERIC C4A2 REPEATS OF CILIATE MACRONUCLEAR RIBOSOMAL-RNA GENE MOLECULES
8 15
66 4 13 57 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85 (14): 5151-5155
YU GL; HASSON M; BLACKBURN EH
CIRCULAR RIBOSOMAL DNA PLASMIDS TRANSFORM TETRAHYMENA-THERMOPHILA BY HOMOLOGOUS RECOMBINATION WITH ENDOGENOUS MACRONUCLEAR RIBOSOMAL DNA
8 36
67 7 50 88 1994 EMBO JOURNAL 13 (23): 5721-5731
BHATTACHARYYA A; BLACKBURN EH
ARCHITECTURE OF TELOMERASE RNA
8 46
68 19 66 103 1995 GENES & DEVELOPMENT 9 (1): 59-71
KIRK KE; BLACKBURN EH
AN UNUSUAL SEQUENCE ARRANGEMENT IN THE TELOMERES OF THE GERM-LINE MICRONUCLEUS IN TETRAHYMENA-THERMOPHILA
8 19
69 25 108 158 2001 CELL 106 (6): 661-673
Blackburn EH
Switching and signaling at the telomere
8 429
70 4 9 67 1990 CELL 60 (4): 529-530
LUNDBLAD V; BLACKBURN EH
RNA-DEPENDENT POLYMERASE MOTIFS IN EST1 - TENTATIVE IDENTIFICATION OF A PROTEIN-COMPONENT OF AN ESSENTIAL YEAST TELOMERASE
7 43
# LCR NCR Node / Date / Journal / Author LCS GCS
71 9 32 69 1990 MOLECULAR AND CELLULAR BIOLOGY 10 (5): 2070-2080
YU GL; BLACKBURN EH
AMPLIFICATION OF TANDEMLY REPEATED ORIGIN CONTROL SEQUENCES CONFERS A REPLICATION ADVANTAGE ON RDNA REPLICONS IN TETRAHYMENA-THERMOPHILA
7 31
72 8 34 146 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (12): 6621-6625
Gilley D; Blackburn EH
The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein
7 50
73 14 48 159 2001 CURRENT BIOLOGY 11 (16): 1240-1250
Chan SWL; Chang J; Prescott J; Blackburn EH
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases
7 53
74 8 40 170 2003 GENES & DEVELOPMENT 17 (9): 1078-1083
Ly H; Xu LF; Rivera MA; Parslow TG; Blackburn EH
A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase
7 28
75 1 18 8 1978 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 43: 1293-1296
YAO MC; Blackburn EH; GALL JG
AMPLIFICATION OF THE RIBOSOMAL-RNA GENES IN TETRAHYMENA
6 32
76 10 47 47 1987 NUCLEIC ACIDS RESEARCH 15 (15): 6273-6292
BUDARF M; Blackburn EH
S1 NUCLEASE SENSITIVITY OF A DOUBLE-STRANDED TELOMERIC DNA-SEQUENCE
6 28
77 18 32 99 1994 NUCLEIC ACIDS RESEARCH 22 (6): 893-900
STRAHL C; BLACKBURN EH
THE EFFECTS OF NUCLEOSIDE ANALOGS ON TELOMERASE AND TELOMERES IN TETRAHYMENA
6 80
78 13 38 126 1998 EMBO JOURNAL 17 (4): 1152-1160
Wang H; Gilley D; Blackburn EH
A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase
6 23
79 34 178 148 2000 ANNUAL REVIEW OF GENETICS 34: 331-358
McEachern MJ; Krauskopf A; Blackburn EH
Telomeres and their control
6 272
80 10 43 177 2004 CANCER RESEARCH 64 (14): 4833-4840
Li S; Rosenberg JE; Donjacour AA; Botchkina IL; Hom YK; et al.
Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA
6 35
# LCR NCR Node / Date / Journal / Author LCS GCS
81 2 25 13 1981 JOURNAL OF CELL BIOLOGY 90 (2): 515-520
YAO MC; Blackburn EH; GALL J
TANDEMLY REPEATED C-C-C-C-A-A HEXANUCLEOTIDE OF TETRAHYMENA RDNA IS PRESENT ELSEWHERE IN THE GENOME AND MAY BE RELATED TO THE ALTERATION OF THE SOMATIC GENOME
5 29
82 5 65 18 1982 CELL NUCLEUS 10: 145-170
BLACKBURN EH
CHARACTERIZATION AND SPECIES-DIFFERENCES OF RDNA - PROTOZOANS
5 20
83 7 40 48 1987 NUCLEIC ACIDS RESEARCH 15 (22): 9143-9152
FORNEY J; HENDERSON ER; BLACKBURN EH
IDENTIFICATION OF THE TELOMERIC SEQUENCE OF THE ACELLULAR SLIME-MOLDS DIDYMIUM-IRIDIS AND PHYSARUM-POLYCEPHALUM
5 48
84 6 26 62 1989 MOLECULAR AND CELLULAR BIOLOGY 9 (2): 452-460
YAEGER PC; ORIAS E; SHAIU WL; LARSON DD; BLACKBURN EH
THE REPLICATION ADVANTAGE OF A FREE LINEAR RIBOSOMAL-RNA GENE IS RESTORED BY SOMATIC RECOMBINATION IN TETRAHYMENA-THERMOPHILA
5 25
85 11 29 74 1990 SCIENCE 249 (4968): 489-490
BLACKBURN EH
TELOMERES AND THEIR SYNTHESIS
5 51
86 11 44 125 1998 CURRENT GENETICS 33 (2): 83-91
Cohn M; McEachern MJ; Blackburn EH
Telomeric sequence diversity within the genus Saccharomyces
5 24
87 24 61 150 2000 EMBO JOURNAL 19 (12): 3119-3131
Ware TL; Wang H; Blackburn EH
Three telomerases with completely non-telomeric template replacements are catalytically active
5 28
88 5 38 162 2002 GENES & DEVELOPMENT 16 (21): 2800-2812
Seto AG; Livengood AJ; Tzfati Y; Blackburn EH; Cech TR
A bulged stem tethers Est1p to telomerase RNA in budding yeast
5 36
89 5 24 168 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 (26): 16998-17003
Comolli LR; Smirnov I; Xu LF; Blackburn EH; James TL
A molecular switch underlies a human telomerase disease
5 41
90 7 48 174 2003 MOLECULAR CELL 11 (5): 1379-1387
Chan SWL; Blackburn EH
Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining
5 55
# LCR NCR Node / Date / Journal / Author LCS GCS
91 4 38 178 2004 CLINICAL CANCER RESEARCH 10 (15): 4983-4990
Nosrati M; Li S; Bagheri S; Ginzinger D; Blackburn EH; et al.
Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA
5 10
92 13 50 118 1997 EMBO JOURNAL 16 (4): 866-879
Wang H; Blackburn EH
De nova telomere addition by Tetrahymena telomerase in vitro
4 58
93 3 24 135 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (10): 5607-5610
Frenck RW; Blackburn EH; Shannon KM
The rate of telomere sequence loss in human leukocytes varies with age
4 124
94 4 41 147 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (22): 12454-12458
Hsu HL; Gilley D; Blackburn EH; Chen DJ
Ku is associated with the telomere in mammals
4 179
95 13 39 156 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97 (21): 11409-11414
McEachern MJ; Iyer S; Fulton TB; Blackburn EH
Telomere fusions caused by mutating the terminal region of telomeric DNA
4 36
96 12 58 169 2003 EXPERIMENTAL CELL RESEARCH 288 (2): 277-287
Kim M; Xu LF; Blackburn EH
Catalytically active human telomerase mutants with allele-specific biological properties
4 10
97 22 38 171 2003 GENES & DEVELOPMENT 17 (14): 1779-1788
Tzfati Y; Knight Z; Roy R; Blackburn EH
A novel pseudoknot element is essential for the action of a yeast telomerase
4 22
98 7 30 172 2003 MOLECULAR AND CELLULAR BIOLOGY 23 (19): 6849-6856
Ly H; Blackburn EH; Parslow TG
Comprehensive structure-function analysis of the core domain of human telomerase RNA
4 31
99 4 78 173 2003 MOLECULAR BIOLOGY OF THE CELL 14 (2): 556-570
Smith CD; Smith DL; DeRisi JL; Blackburn EH
Telomeric protein distribution and remodeling through the cell cycle in Saccharomyces cerevisiae
4 33
100 13 68 194 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (25): 23709-23717
Li S; Crothers J; Haqq CM; Blackburn EH
Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA
4 19

#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
1	8	35	26 1985 CELL 43 (2): 405-413 GREIDER CW; BLACKBURN EH IDENTIFICATION OF A SPECIFIC TELOMERE TERMINAL TRANSFERASE-ACTIVITY IN TETRAHYMENA EXTRACTS	54	1087
2	8	54	64 1989 NATURE 337 (6205): 331-337 GREIDER CW; BLACKBURN EH A TELOMERIC SEQUENCE IN THE RNA OF TETRAHYMENA TELOMERASE REQUIRED FOR TELOMERE REPEAT SYNTHESIS	54	704
3	17	48	71 1990 NATURE 344 (6262): 126-132 YU GL; BRADLEY JD; ATTARDI LD; BLACKBURN EH INVIVO ALTERATION OF TELOMERE SEQUENCES AND SENESCENCE CAUSED BY MUTATED TETRAHYMENA-TELOMERASE RNAS	52	431
4	8	39	45 1987 CELL 51 (6): 887-898 GREIDER CW; BLACKBURN EH THE TELOMERE TERMINAL TRANSFERASE OF TETRAHYMENA IS A RIBONUCLEOPROTEIN ENZYME WITH 2 KINDS OF PRIMER SPECIFICITY	39	421
5	0	34	9 1978 JOURNAL OF MOLECULAR BIOLOGY 120 (1): 33-53 BLACKBURN EH; GALL JG TANDEMLY REPEATED SEQUENCE AT TERMINI OF EXTRACHROMOSOMAL RIBOSOMAL-RNA GENES IN TETRAHYMENA	38	322
6	16	49	119 1997 GENES & DEVELOPMENT 11 (4): 528-540 Prescott J; Blackburn EH Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro	37	99
7	5	123	22 1984 ANNUAL REVIEW OF BIOCHEMISTRY 53: 163-194 BLACKBURN EH; SZOSTAK JW THE MOLECULAR-STRUCTURE OF CENTROMERES AND TELOMERES	33	502
8	3	31	25 1984 NATURE 310 (5973): 154-157 SHAMPAY J; SZOSTAK JW; BLACKBURN EH DNA-SEQUENCES OF TELOMERES MAINTAINED IN YEAST	33	269
9	12	43	108 1995 NATURE 376 (6539): 403-409 MCEACHERN MJ; BLACKBURN EH RUNAWAY TELOMERE ELONGATION CAUSED BY TELOMERASE RNA GENE-MUTATIONS	33	241
10	10	39	73 1990 SCIENCE 247 (4942): 546-552 SHIPPENLENTZ D; BLACKBURN EH FUNCTIONAL EVIDENCE FOR AN RNA TEMPLATE IN TELOMERASE	32	230
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
11	18	45	76 1991 CELL 67 (4): 823-832 YU GL; BLACKBURN EH DEVELOPMENTALLY PROGRAMMED HEALING OF CHROMOSOMES BY TELOMERASE IN TETRAHYMENA	31	160
12	3	19	115 1996 NATURE 383 (6598): 354-357 Krauskopf A; Blackburn EH Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats	30	116
13	15	37	104 1995 GENES & DEVELOPMENT 9 (18): 2214-2226 GILLEY D; LEE MS; BLACKBURN EH ALTERING SPECIFIC TELOMERASE RNA TEMPLATE RESIDUES AFFECTS ACTIVE-SITE FUNCTION	26	86
14	14	30	110 1995 SCIENCE 269 (5222): 396-400 COHN M; BLACKBURN EH TELOMERASE IN YEAST	25	170
15	2	39	17 1982 CELL 29 (1): 245-255 SZOSTAK JW; BLACKBURN EH CLONING YEAST TELOMERES ON LINEAR PLASMID VECTORS	24	290
16	9	51	83 1993 CELL 73 (2): 347-360 LUNDBLAD V; BLACKBURN EH AN ALTERNATIVE PATHWAY FOR YEAST TELOMERE MAINTENANCE RESCUES EST1-SENESCENCE	23	435
17	11	56	112 1996 GENES & DEVELOPMENT 10 (14): 1822-1834 McEachern MJ; Blackburn EH Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase	23	159
18	13	33	44 1987 CELL 50 (3): 477-483 LARSON DD; SPANGLER EA; BLACKBURN EH DYNAMICS OF TELOMERE LENGTH VARIATION IN TETRAHYMENA THERMOPHILA	22	97
19	6	22	56 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85 (2): 534-538 SHAMPAY J; BLACKBURN EH GENERATION OF TELOMERE-LENGTH HETEROGENEITY IN SACCHAROMYCES-CEREVISIAE	21	108
20	11	65	75 1991 CELL 67 (2): 343-353 ROMERO DP; BLACKBURN EH A CONSERVED SECONDARY STRUCTURE FOR TELOMERASE RNA	21	159
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
21	15	72	79 1991 NATURE 350 (6319): 569-573 BLACKBURN EH STRUCTURE AND FUNCTION OF TELOMERES	20	1530
22	15	35	114 1996 MOLECULAR AND CELLULAR BIOLOGY 16 (1): 66-75 Gilley D; Blackburn EH Specific RNA residue interactions required for enzymatic functions of Tetrahymenatelomerase	20	68
23	11	66	120 1997 GENES & DEVELOPMENT 11 (21): 2790-2800 Prescott J; Blackburn EH Functionally interacting telomerase RNAs in the yeast telomerase complex	20	85
24	0	0	24 1984 CELL 37 (1): 7-8 BLACKBURN EH TELOMERES - DO THE ENDS JUSTIFY THE MEANS	19	100
25	15	31	81 1992 ANNUAL REVIEW OF BIOCHEMISTRY 61: 113-129 BLACKBURN EH TELOMERASES	19	444
26	6	29	124 1997 SCIENCE 275 (5305): 1478-1481 Kirk KE; Harmon BP; Reichardt IK; Sedat JW; Blackburn EH Block in anaphase chromosome separation caused by a telomerase template mutation	19	157
27	12	22	86 1993 MOLECULAR AND CELLULAR BIOLOGY 13 (10): 6586-6599 LEE MS; BLACKBURN EH SEQUENCE-SPECIFIC DNA PRIMER EFFECTS ON TELOMERASE POLYMERIZATION ACTIVITY	18	71
28	7	21	87 1994 CELL 77 (5): 621-623 BLACKBURN EH TELOMERES - NO END IN SIGHT	18	200
29	15	50	127 1998 GENES & DEVELOPMENT 12 (20): 3286-3300 Roy J; Fulton TB; Blackburn EH Specific telomerase RNA residues distant from the template are essential for telomerase function	18	53
30	2	23	11 1981 CELL 23 (2): 459-466 PAN WC; BLACKBURN EH SINGLE EXTRACHROMOSOMAL RIBOSOMAL-RNA GENE COPIES ARE SYNTHESIZED DURING AMPLIFICATION OF THE RDNA IN TETRAHYMENA	17	62
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
31	7	15	63 1989 MOLECULAR AND CELLULAR BIOLOGY 9 (6): 2761-2764 SHIPPENLENTZ D; BLACKBURN EH TELOMERE TERMINAL TRANSFERASE-ACTIVITY FROM EUPLOTES-CRASSUS ADDS LARGE NUMBERS OF TTTTGGGG REPEATS ONTO TELOMERIC PRIMERS	17	95
32	13	43	141 1999 JOURNAL OF CELL BIOLOGY 145 (2): 203-214 Smith CD; Blackburn EH Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast	17	40
33	2	36	12 1981 CELL 24 (2): 313-320 KATZEN AL; CANN GM; BLACKBURN EH SEQUENCE-SPECIFIC FRAGMENTATION OF MACRONUCLEAR DNA IN A HOLOTRICHOUS CILIATE	15	70
34	9	46	34 1986 CELL 47 (2): 229-240 LARSON DD; BLACKBURN EH; YAEGER PC; ORIAS E CONTROL OF RDNA REPLICATION IN TETRAHYMENA INVOLVES A CIS-ACTING UPSTREAM REPEAT OF A PROMOTER ELEMENT	15	104
35	7	28	136 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (21): 12486-12491 Krauskopf A; Blackburn EH Rap1 protein regulates telomere turnover in yeast	15	39
36	12	48	154 2000 NATURE 408 (6808): 53-56 Blackburn EH Telomere states and cell fates	15	294
37	4	33	16 1982 CELL 28 (3): 595-604 PAN WC; ORIAS E; FLACKS M; BLACKBURN EH ALLELE-SPECIFIC, SELECTIVE AMPLIFICATION OF A RIBOSOMAL-RNA GENE IN TETRAHYMENA THERMOPHILA	14	56
38	4	50	30 1985 NUCLEIC ACIDS RESEARCH 13 (7): 2661-2680 CHALLONER PB; AMIN AA; PEARLMAN RE; BLACKBURN EH CONSERVED ARRANGEMENTS OF REPEATED DNA-SEQUENCES IN NONTRANSCRIBED SPACERS OF CILIATE RIBOSOMAL-RNA GENES - EVIDENCE FOR MOLECULAR COEVOLUTION	14	46
39	21	44	130 1998 MOLECULAR AND CELLULAR BIOLOGY 18 (9): 4961-4970 Fulton TB; Blackburn EH Identification of Kluyveromyces lactis telomerase: Discontinuous synthesis along the 30-nucleotide-long templating domain	14	30
40	4	43	145 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (7): 3723-3728 Zhu JY; Wang H; Bishop JM; Blackburn EH Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening	14	214
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
41	11	37	102 1994 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91 (8): 3453-3457 MCEACHERN MJ; BLACKBURN EH A CONSERVED SEQUENCE MOTIF WITHIN THE EXCEPTIONALLY DIVERSE TELOMERIC SEQUENCES OF BUDDING YEASTS	13	58
42	14	45	153 2000 MOLECULAR AND CELLULAR BIOLOGY 20 (8): 2941-2948 Prescott JC; Blackburn EH Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres	13	34
43	2	31	15 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78 (4): 2263-2267 BLACKBURN EH; CHIOU SS NON-NUCLEOSOMAL PACKAGING OF A TANDEMLY REPEATED DNA-SEQUENCE AT TERMINI OF EXTRACHROMOSOMAL DNA CODING FOR RIBOSOMAL-RNA IN TETRAHYMENA	12	67
44	8	42	46 1987 CELL 51 (6): 899-908 HENDERSON E; HARDIN CC; WALK SK; TINOCO I; BLACKBURN EH TELOMERIC DNA OLIGONUCLEOTIDES FORM NOVEL INTRAMOLECULAR STRUCTURES CONTAINING GUANINE GUANINE BASE-PAIRS	12	342
45	0	0	111 1995 TELOMERES BLACKBURN EH; GREIDER CW Telomeres (Monograph 29), edited by Elizabeth H. Blackburn and Carol W. Greider.	12	159
46	4	32	23 1984 CELL 36 (2): 447-457 BLACKBURN EH; CHALLONER PB IDENTIFICATION OF A TELOMERIC DNA-SEQUENCE IN TRYPANOSOMA-BRUCEI	11	128
47	2	21	31 1985 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82 (9): 2844-2846 BRUNS PJ; KATZEN AL; MARTIN L; BLACKBURN EH A DRUG-RESISTANT MUTATION IN THE RIBOSOMAL DNA OF TETRAHYMENA	11	48
48	10	25	61 1989 MOLECULAR AND CELLULAR BIOLOGY 9 (1): 345-348 HENDERSON ER; BLACKBURN EH AN OVERHANGING 3' TERMINUS IS A CONSERVED FEATURE OF TELOMERES	11	193
49	9	26	66 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86 (21): 8487-8491 YU GL; BLACKBURN EH TRANSFORMATION OF TETRAHYMENA-THERMOPHILA WITH A MUTATED CIRCULAR RIBOSOMAL DNA PLASMA VECTOR	11	34
50	9	16	84 1993 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 58: 707-718 LEE MS; GALLAGHER RC; BRADLEY J; BLACKBURN EH IN-VIVO AND IN-VITRO STUDIES OF TELOMERES AND TELOMERASE	11	28
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
51	16	52	155 2000 NATURE STRUCTURAL BIOLOGY 7 (10): 847-850 Blackburn EH The end of the (DNA) line	11	59
52	12	37	160 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98 (14): 7982-7987 Kim MM; Rivera MA; Botchkina IL; Shalaby R; Thor AD; et al. A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation	11	62
53	9	54	27 1985 CELL 43 (3): 747-758 CHERRY JM; BLACKBURN EH THE INTERNALLY LOCATED TELOMERIC SEQUENCES IN THE GERM-LINE CHROMOSOMES OF TETRAHYMENA ARE AT THE ENDS OF TRANSPOSON-LIKE ELEMENTS	10	73
54	3	42	29 1985 MOLECULAR AND CELLULAR BIOLOGY 5 (8): 2039-2050 HOWARD EA; BLACKBURN EH REPRODUCIBLE AND VARIABLE GENOMIC REARRANGEMENTS OCCUR IN THE DEVELOPING SOMATIC NUCLEUS OF THE CILIATE TETRAHYMENA-THERMOPHILA	10	54
55	8	42	55 1988 NUCLEIC ACIDS RESEARCH 16 (12): 5569-5585 SPANGLER EA; RYAN T; BLACKBURN EH DEVELOPMENTALLY REGULATED TELOMERE ADDITION IN TETRAHYMENA-THERMOPHILA	10	21
56	16	30	106 1995 JOURNAL OF EUKARYOTIC MICROBIOLOGY 42 (1): 32-43 ROMERO DP; BLACKBURN EH CIRCULAR RDNA REPLICONS PERSIST IN TETRAHYMENA-THERMOPHILA TRANSFORMANTS SYNTHESIZING GGGGTC TELOMERIC REPEATS	10	18
57	7	26	157 2000 SCIENCE 288 (5467): 863-867 Tzfati Y; Fulton TB; Roy J; Blackburn EH Template boundary in a yeast telomerase specified by RNA structure	10	47
58	2	42	28 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260 (10): 6334-6340 SPANGLER EA; BLACKBURN EH THE NUCLEOTIDE-SEQUENCE OF THE 17-S RIBOSOMAL-RNA GENE OF TETRAHYMENA-THERMOPHILA AND THE IDENTIFICATION OF POINT MUTATIONS RESULTING IN RESISTANCE TO THE ANTIBIOTICS PAROMOMYCIN AND HYGROMYCIN	9	140
59	7	42	36 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261 (1): 363-369 BUDARF ML; BLACKBURN EH CHROMATIN STRUCTURE OF THE TELOMERIC REGION AND 3'-NONTRANSCRIBED SPACER OF TETRAHYMENA RIBOSOMAL-RNA GENES	9	47
60	5	34	54 1988 MOLECULAR AND CELLULAR BIOLOGY 8 (1): 251-258 FORNEY JD; BLACKBURN EH DEVELOPMENTALLY CONTROLLED TELOMERE ADDITION IN WILD-TYPE AND MUTANT PARAMECIA	9	88
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
61	15	26	59 1989 GENOME 31 (2): 553-560 BLACKBURN EH; GREIDER CW; HENDERSON E; LEE MS; SHAMPAY J; et al. RECOGNITION AND ELONGATION OF TELOMERES BY TELOMERASE	9	38
62	12	49	113 1996 MOLECULAR AND CELLULAR BIOLOGY 16 (1): 53-65 Strahl C; Blackburn EH Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines	9	231
63	8	29	123 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (7): 2823-2827 Bhattacharyya A; Blackburn EH A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains	9	39
64	13	77	33 1986 ANNUAL REVIEW OF GENETICS 20: 501-521 BLACKBURN EH; KARRER KM GENOMIC REORGANIZATION IN CILIATED PROTOZOANS	8	61
65	12	31	43 1986 NUCLEIC ACIDS RESEARCH 14 (15): 6299-6311 CHALLONER PB; BLACKBURN EH CONSERVATION OF SEQUENCES ADJACENT TO THE TELOMERIC C4A2 REPEATS OF CILIATE MACRONUCLEAR RIBOSOMAL-RNA GENE MOLECULES	8	15
66	4	13	57 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85 (14): 5151-5155 YU GL; HASSON M; BLACKBURN EH CIRCULAR RIBOSOMAL DNA PLASMIDS TRANSFORM TETRAHYMENA-THERMOPHILA BY HOMOLOGOUS RECOMBINATION WITH ENDOGENOUS MACRONUCLEAR RIBOSOMAL DNA	8	36
67	7	50	88 1994 EMBO JOURNAL 13 (23): 5721-5731 BHATTACHARYYA A; BLACKBURN EH ARCHITECTURE OF TELOMERASE RNA	8	46
68	19	66	103 1995 GENES & DEVELOPMENT 9 (1): 59-71 KIRK KE; BLACKBURN EH AN UNUSUAL SEQUENCE ARRANGEMENT IN THE TELOMERES OF THE GERM-LINE MICRONUCLEUS IN TETRAHYMENA-THERMOPHILA	8	19
69	25	108	158 2001 CELL 106 (6): 661-673 Blackburn EH Switching and signaling at the telomere	8	429
70	4	9	67 1990 CELL 60 (4): 529-530 LUNDBLAD V; BLACKBURN EH RNA-DEPENDENT POLYMERASE MOTIFS IN EST1 - TENTATIVE IDENTIFICATION OF A PROTEIN-COMPONENT OF AN ESSENTIAL YEAST TELOMERASE	7	43
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
71	9	32	69 1990 MOLECULAR AND CELLULAR BIOLOGY 10 (5): 2070-2080 YU GL; BLACKBURN EH AMPLIFICATION OF TANDEMLY REPEATED ORIGIN CONTROL SEQUENCES CONFERS A REPLICATION ADVANTAGE ON RDNA REPLICONS IN TETRAHYMENA-THERMOPHILA	7	31
72	8	34	146 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (12): 6621-6625 Gilley D; Blackburn EH The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein	7	50
73	14	48	159 2001 CURRENT BIOLOGY 11 (16): 1240-1250 Chan SWL; Chang J; Prescott J; Blackburn EH Altering telomere structure allows telomerase to act in yeast lacking ATM kinases	7	53
74	8	40	170 2003 GENES & DEVELOPMENT 17 (9): 1078-1083 Ly H; Xu LF; Rivera MA; Parslow TG; Blackburn EH A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase	7	28
75	1	18	8 1978 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 43: 1293-1296 YAO MC; Blackburn EH; GALL JG AMPLIFICATION OF THE RIBOSOMAL-RNA GENES IN TETRAHYMENA	6	32
76	10	47	47 1987 NUCLEIC ACIDS RESEARCH 15 (15): 6273-6292 BUDARF M; Blackburn EH S1 NUCLEASE SENSITIVITY OF A DOUBLE-STRANDED TELOMERIC DNA-SEQUENCE	6	28
77	18	32	99 1994 NUCLEIC ACIDS RESEARCH 22 (6): 893-900 STRAHL C; BLACKBURN EH THE EFFECTS OF NUCLEOSIDE ANALOGS ON TELOMERASE AND TELOMERES IN TETRAHYMENA	6	80
78	13	38	126 1998 EMBO JOURNAL 17 (4): 1152-1160 Wang H; Gilley D; Blackburn EH A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase	6	23
79	34	178	148 2000 ANNUAL REVIEW OF GENETICS 34: 331-358 McEachern MJ; Krauskopf A; Blackburn EH Telomeres and their control	6	272
80	10	43	177 2004 CANCER RESEARCH 64 (14): 4833-4840 Li S; Rosenberg JE; Donjacour AA; Botchkina IL; Hom YK; et al. Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA	6	35
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
81	2	25	13 1981 JOURNAL OF CELL BIOLOGY 90 (2): 515-520 YAO MC; Blackburn EH; GALL J TANDEMLY REPEATED C-C-C-C-A-A HEXANUCLEOTIDE OF TETRAHYMENA RDNA IS PRESENT ELSEWHERE IN THE GENOME AND MAY BE RELATED TO THE ALTERATION OF THE SOMATIC GENOME	5	29
82	5	65	18 1982 CELL NUCLEUS 10: 145-170 BLACKBURN EH CHARACTERIZATION AND SPECIES-DIFFERENCES OF RDNA - PROTOZOANS	5	20
83	7	40	48 1987 NUCLEIC ACIDS RESEARCH 15 (22): 9143-9152 FORNEY J; HENDERSON ER; BLACKBURN EH IDENTIFICATION OF THE TELOMERIC SEQUENCE OF THE ACELLULAR SLIME-MOLDS DIDYMIUM-IRIDIS AND PHYSARUM-POLYCEPHALUM	5	48
84	6	26	62 1989 MOLECULAR AND CELLULAR BIOLOGY 9 (2): 452-460 YAEGER PC; ORIAS E; SHAIU WL; LARSON DD; BLACKBURN EH THE REPLICATION ADVANTAGE OF A FREE LINEAR RIBOSOMAL-RNA GENE IS RESTORED BY SOMATIC RECOMBINATION IN TETRAHYMENA-THERMOPHILA	5	25
85	11	29	74 1990 SCIENCE 249 (4968): 489-490 BLACKBURN EH TELOMERES AND THEIR SYNTHESIS	5	51
86	11	44	125 1998 CURRENT GENETICS 33 (2): 83-91 Cohn M; McEachern MJ; Blackburn EH Telomeric sequence diversity within the genus Saccharomyces	5	24
87	24	61	150 2000 EMBO JOURNAL 19 (12): 3119-3131 Ware TL; Wang H; Blackburn EH Three telomerases with completely non-telomeric template replacements are catalytically active	5	28
88	5	38	162 2002 GENES & DEVELOPMENT 16 (21): 2800-2812 Seto AG; Livengood AJ; Tzfati Y; Blackburn EH; Cech TR A bulged stem tethers Est1p to telomerase RNA in budding yeast	5	36
89	5	24	168 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 (26): 16998-17003 Comolli LR; Smirnov I; Xu LF; Blackburn EH; James TL A molecular switch underlies a human telomerase disease	5	41
90	7	48	174 2003 MOLECULAR CELL 11 (5): 1379-1387 Chan SWL; Blackburn EH Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining	5	55
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
91	4	38	178 2004 CLINICAL CANCER RESEARCH 10 (15): 4983-4990 Nosrati M; Li S; Bagheri S; Ginzinger D; Blackburn EH; et al. Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA	5	10
92	13	50	118 1997 EMBO JOURNAL 16 (4): 866-879 Wang H; Blackburn EH De nova telomere addition by Tetrahymena telomerase in vitro	4	58
93	3	24	135 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (10): 5607-5610 Frenck RW; Blackburn EH; Shannon KM The rate of telomere sequence loss in human leukocytes varies with age	4	124
94	4	41	147 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 (22): 12454-12458 Hsu HL; Gilley D; Blackburn EH; Chen DJ Ku is associated with the telomere in mammals	4	179
95	13	39	156 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97 (21): 11409-11414 McEachern MJ; Iyer S; Fulton TB; Blackburn EH Telomere fusions caused by mutating the terminal region of telomeric DNA	4	36
96	12	58	169 2003 EXPERIMENTAL CELL RESEARCH 288 (2): 277-287 Kim M; Xu LF; Blackburn EH Catalytically active human telomerase mutants with allele-specific biological properties	4	10
97	22	38	171 2003 GENES & DEVELOPMENT 17 (14): 1779-1788 Tzfati Y; Knight Z; Roy R; Blackburn EH A novel pseudoknot element is essential for the action of a yeast telomerase	4	22
98	7	30	172 2003 MOLECULAR AND CELLULAR BIOLOGY 23 (19): 6849-6856 Ly H; Blackburn EH; Parslow TG Comprehensive structure-function analysis of the core domain of human telomerase RNA	4	31
99	4	78	173 2003 MOLECULAR BIOLOGY OF THE CELL 14 (2): 556-570 Smith CD; Smith DL; DeRisi JL; Blackburn EH Telomeric protein distribution and remodeling through the cell cycle in Saccharomyces cerevisiae	4	33
100	13	68	194 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (25): 23709-23717 Li S; Crothers J; Haqq CM; Blackburn EH Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA	4	19

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