# | Cited nodes | Nodes / Authors | GCS | LCS |
1 | 0 | 8 1998 SCIENCE 281(5382):1509-1512
He TC; Sparks AB; Rago C; Hermeking H; Zawel L; da Costa LT; Morin PJ; Vogelstein B; Kinzler KW Identification of c-MYC as a target of the APC pathway | 919 | 918
|
2 | 1 | 112 1999 NATURE 398(6726):422-426
Tetsu O; McCormick F beta-catenin regulates expression of cyclin D1 in colon carcinoma cells | 698 | 498
|
3 | 24 | 237 2000 GENES & DEVELOPMENT 14(15):1837-1851
Polakis P Wnt signaling and cancer | 448 | 140
|
4 | 4 | 41 1999 CELL 99(3):335-345
He TC; Chan TA; Vogelstein B; Kinzler KW PPAR delta is an APC-regulated target of nonsteroidal anti-inflammatory drugs | 351 | 104
|
5 | 1 | 135 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(10):5522-5527
Shtutman M; Zhurinsky J; Simcha I; Albanese C; D'Amico M; Pestell R; Ben-Ze'ev A The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway | 351 | 229
|
6 | 1 | 108 1999 MOLECULAR AND CELLULAR BIOLOGY 19(1):1-11
Dang CV c-myc target genes involved in cell growth, apoptosis, and metabolism | 309 | 31
|
7 | 5 | 236 2000 GENES & DEVELOPMENT 14(13):1553-1577
Goodman RH; Smolik S CBP/p300 in cell growth, transformation, and development | 286 | 4
|
8 | 4 | 302 2000 NATURE GENETICS 24(3):245-250
Satoh S; Daigo Y; Furukawa Y; Kato T; Miwa N; Nishiwaki T; Kawasoe T; Ishiguro H; Fujita M; Tokino T; Sasaki Y; Imaoka S; Murata M; Shimano T; Yamaoka Y; Nakamura Y AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1 | 257 | 122
|
9 | 1 | 14 1999 ANNUAL REVIEW OF BIOCHEMISTRY 68():965-1014
Chan TO; Rittenhouse SE; Tsichlis PN AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation | 242 | 1
|
10 | 1 | 4 1998 CELL 95(5):605-614
Gat U; DasGupta R; Degenstein L; Fuchs E De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin | 239 | 71
|
11 | 1 | 58 1999 CURRENT OPINION IN GENETICS & DEVELOPMENT 9(1):15-21
Polakis P The oncogenic activation of beta-catenin | 207 | 100
|
12 | 1 | 119 1999 ONCOGENE 18(18):2883-2891
Crawford HC; Fingleton BM; Rudolph-Owen LA; Goss KJH; Rubinfeld B; Polakis P; Matrisian LM The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors | 206 | 146
|
13 | 1 | 133 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(4):1603-1608
Mann B; Gelos M; Siedow A; Hanski ML; Gratchev A; Ilyas M; Bodmer WF; Moyer MP; Riecken EO; Buhr HJ; Hanski C Target genes of beta-catenin-T cell-factor lymphoid-enhancer-factor signaling in human colorectal carcinomas | 204 | 147
|
14 | 1 | 102 1999 JOURNAL OF THE NATIONAL CANCER INSTITUTE 91(11):916-932
Potter JD Colorectal cancer: Molecules and populations | 193 | 6
|
15 | 15 | 196 2000 CELL 103(2):311-320
Bienz M; Clevers H Linking colorectal cancer to Wnt signaling | 190 | 60
|
16 | 11 | 130 1999 ONCOGENE 18(55):7860-7872
Miller JR; Hocking AM; Brown JD; Moon RT Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways | 189 | 35
|
17 | 4 | 195 2000 CELL 100(1):143-155
Fuchs E; Segre JA Stem cells: A new lease on life | 182 | 5
|
18 | 7 | 22 1999 BIOESSAYS 21(12):1021-1030
Morin PJ beta-catenin signaling and cancer | 181 | 73
|
19 | 1 | 74 1999 GENES & DEVELOPMENT 13(5):505-510
Maniatis T A ubiquitin ligase complex essential for the NF-kappa B, Wnt/Wingless, and Hedgehog signaling pathways | 180 | 15
|
20 | 1 | 115 1999 NATURE GENETICS 23(4):387-388
Velculescu VE; Madden SL; Zhang L; Lash AE; Yu J; Rago C; Lal A; Wang CJ; Beaudry GA; Ciriello KM; Cook BP; Dufault MR; Ferguson AT; Gao YH; He TC; Hermeking H; Hiraldo SK; Hwang PM; Lopez MA; Luderer HF; Mathews B; Petroziello JM; Polyak K; Zawel L; Zhang W; Zhang XM; Zhou W; Haluska FG; Jen J; Sukumar S; Landes GM; Riggins GJ; Vogelstein B; Kinzler KW Analysis of human transcriptomes | 159 | 11
|
21 | 2 | 114 1999 NATURE GENETICS 21(4):410-413
Chan EF; Gat U; McNiff JM; Fuchs E A common human skin tumour is caused by activating mutations in beta-catenin | 155 | 69
|
22 | 2 | 120 1999 ONCOGENE 18(19):2967-2987
Prendergast GC Mechanisms of apoptosis by c-Myc | 152 | 8
|
23 | 1 | 37 1999 CANCER RESEARCH 59(21):5403-5407
Lal A; Lash AE; Altschul SF; Velculescu V; Zhang L; McLendon RE; Marra MA; Prange C; Morin PJ; Polyak K; Papadopoulos N; Vogelstein B; Kinzler KW; Strausberg RL; Riggins GJ A public database for gene expression in human cancers | 144 | 12
|
24 | 2 | 56 1999 CURRENT OPINION IN CELL BIOLOGY 11(2):233-240
Eastman Q; Grosschedl R Regulation of LEF-1/TCF transcription factors by Wnt and other signals | 144 | 31
|
25 | 2 | 121 1999 ONCOGENE 18(19):3004-3016
Nesbit CE; Tersak JM; Prochownik EV MYC oncogenes and human neoplastic disease | 140 | 9
|
26 | 1 | 511 2001 MOLECULAR CELL 7(3):673-682
Yu J; Zhang L; Hwang PM; Kinzler KW; Vogelstein B PUMA induces the rapid apoptosis of colorectal cancer cells | 137 | 2
|
27 | 3 | 139 1999 SCIENCE 285(5435):1923-1926
Roose J; Huls G; van Beest M; Moerer P; van der Horn K; Goldschmeding R; Logtenberg T; Cleavers H Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1 | 124 | 82
|
28 | 1 | 7 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(25):14717-14722
Pennica D; Swanson TA; Welsh JW; Roy MA; Lawrence DA; Lee J; Brush J; Taneyhill LA; Deuel B; Lew M; Watanabe C; Cohen RL; Melhem MF; Finley GG; Quirke P; Goddard AD; Hillan KJ; Gurney AL; Botstein D; Levine AJ WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors | 123 | 52
|
29 | 1 | 138 1999 SCIENCE 283(5410):2089-2091
Seeling JM; Miller JR; Gil R; Moon RT; White R; Virshup DM Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A | 117 | 44
|
30 | 10 | 390 2001 CELL 105(4):533-545
Huelsken J; Vogel R; Erdmann B; Cotsarelis G; Birchmeier W beta-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin | 110 | 20
|
31 | 2 | 40 1999 CELL 98(6):779-790
Johnston LA; Prober DA; Edgar BA; Eisenman RN; Gallant P Drosophila myc regulates cellular growth during development | 109 | 9
|
32 | 5 | 301 2000 NATURE CELL BIOLOGY 2(9):653-660
Henderson BR Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover | 109 | 39
|
33 | 2 | 299 2000 NATURE 403(6771):781-785
Nishita M; Hashimoto MK; Ogata S; Laurent MN; Ueno N; Shibuya H; Cho KWY Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer | 108 | 18
|
34 | 1 | 31 1999 CANCER RESEARCH 59(4):826-830
Horikawa I; Cable PL; Afshari C; Barrett JJ Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene | 107 | 2
|
35 | 4 | 13 1999 AMERICAN JOURNAL OF PATHOLOGY 155(4):1033-1038
Brabletz T; Jung A; Dag S; Hlubek F; Kirchner T beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer | 104 | 66
|
36 | 1 | 81 1999 HUMAN MOLECULAR GENETICS 8(10):1821-1832
Claverie JM Computational methods for the identification of differential and coordinated gene expression | 98 | 1
|
37 | 6 | 513 2001 NATURE 411(6835):349-354
Taipale J; Beachy PA The Hedgehog and Wnt signaling pathways in cancer | 98 | 11
|
38 | 1 | 232 2000 GENES & DEVELOPMENT 14(3):272-277
Kung AL; Rebel VI; Bronson RT; Ch'ng LE; Sieff CA; Livingston DM; Yao TP Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP | 97 | 2
|
39 | 1 | 30 1999 CANCER RESEARCH 59(2):269-273
Koch A; Denkhaus D; Albrecht S; Leuschner I; von Schweinitz D; Pietsch T Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene | 95 | 44
|
40 | 1 | 2 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 252(1):117-122
Sagara N; Toda G; Hirai M; Terada M; Katoh M Molecular cloning, differential expression, and chromosomal localization of human Frizzled-1, Frizzled-2 and Frizzled-7 | 94 | 11
|
41 | 1 | 151 2000 ADVANCES IN CANCER RESEARCH, VOL 77 77():1-24
Barker N; Morin PJ; Clevers H The yin-yang of TCF/beta-catenin signaling | 93 | 44
|
42 | 1 | 10 1999 AMERICAN JOURNAL OF PATHOLOGY 154(4):965-973
Jankowski JA; Wright NA; Meltzer SJ; Triadafilopoulos G; Geboes K; Casson AG; Kerr D; Young LS Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus | 91 | 1
|
43 | 1 | 32 1999 CANCER RESEARCH 59(8):1811-1815
Garcia-Rostan G; Tallini G; Herrero A; D'Aquila TG; Carcangiu ML; Rimm DL Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma | 90 | 0
|
44 | 2 | 321 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(5):2229-2234
Hermeking H; Rago C; Schuhmacher M; Li Q; Barrett JF; Obaya AJ; O'Connell BC; Mateyak MK; Tam W; Kohlhuber F; Dang CV; Sedivy JM; Eick D; Vogelstein B; Kinzler KW Identification of CDK4 as a target of c-MYC | 89 | 15
|
45 | 1 | 34 1999 CANCER RESEARCH 59(12):2759-2765
Bieche I; Laurendeau I; Tozlu S; Olivi M; Vidaud D; Lidereau R; Vidaud M Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay | 88 | 7
|
46 | 1 | 88 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(16):10681-10684
Yamamoto H; Kishida S; Kishida M; Ikeda S; Takada S; Kikuchi A Phosphorylation of Axin, a Wnt signal negative regulator, by glycogen synthase kinase-3 beta regulates its stability | 87 | 40
|
47 | 5 | 276 2000 JOURNAL OF CELL BIOLOGY 149(2):249-254
Takemaru KI; Moon RT The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression | 85 | 43
|
48 | 4 | 322 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(8):4262-4266
Lin SY; Xia WY; Wang JC; Kwong KY; Spohn B; Wen Y; Pestell RG; Hung MC beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression | 85 | 39
|
49 | 2 | 512 2001 MOLECULAR CELL 7(5):915-926
Matsuzawa S; Reed JC Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses | 84 | 20
|
50 | 1 | 109 1999 MOLECULAR AND CELLULAR BIOLOGY 19(8):5576-5587
Gradl D; Kuhl M; Wedlich D The Wnt/Wg signal transducer beta-catenin controls fibronectin expression | 83 | 49
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51 | 2 | 708 2002 JOURNAL OF THE NATIONAL CANCER INSTITUTE 94(4):252-266
Thun MJ; Henley SJ; Patrono C Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues | 83 | 1
|
52 | 1 | 116 1999 ONCOGENE 18(4):849-854
Latres E; Chiaur DS; Pagano M The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin | 81 | 22
|
53 | 1 | 36 1999 CANCER RESEARCH 59(17):4213-4215
Duval A; Gayet J; Zhou XP; Iacopetta B; Thomas G; Hamelin R Frequent frameshift mutations of the TCF-4 gene in colorectal cancers with microsatellite instability | 79 | 23
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54 | 8 | 230 2000 GASTROENTEROLOGY 119(3):854-865
Chung DC The genetic basis of colorectal cancer: Insights into critical pathways of tumorigenesis | 78 | 10
|
55 | 5 | 62 1999 DEVELOPMENT 126(20):4557-4568
DasGupta R; Fuchs E Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation | 77 | 13
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56 | 3 | 428 2001 HUMAN MOLECULAR GENETICS 10(7):699-703
Nevins JR The Rb/E2F pathway and cancer | 77 | 2
|
57 | 2 | 96 1999 JOURNAL OF CELL BIOLOGY 146(4):855-867
Orford K; Orford CC; Byers SW Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest | 76 | 45
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58 | 5 | 391 2001 CELL 105(6):721-732
Dajani R; Fraser E; Roe SM; Young N; Good V; Dale TC; Pearl LH Crystal structure of glycogen synthase kinase 3 beta: Structural basis for phosphate-primed substrate specificity and autoinhibition | 75 | 6
|
59 | 15 | 235 2000 GENES & DEVELOPMENT 14(11):1319-1331
Kolligs FT; Kolligs B; Hajra KM; Hu G; Tani M; Cho KR; Fearon ER gamma-Catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin | 74 | 41
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60 | 1 | 50 1999 CLINICAL CANCER RESEARCH 5(5):945-951
Meyskens FL; Gerner EW Development of difluoromethylornithine (DFMO) as a chemoprevention agent | 71 | 4
|
61 | 2 | 90 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(25):18017-18025
Hecht A; Litterst CM; Huber O; Kemler R Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro | 70 | 35
|
62 | 6 | 416 2001 FASEB JOURNAL 15(12):2057-2072
Tegeder I; Pfeilschifter J; Geisslinger G Cyclooxygenase-independent actions of cyclooxygenase inhibitors | 70 | 0
|
63 | 16 | 166 2000 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1495(2):168-182
Seidensticker MJ; Behrens J Biochemical interactions in the wnt pathway | 67 | 11
|
64 | 5 | 233 2000 GENES & DEVELOPMENT 14(5):585-595
Xu LF; Corcoran RB; Welsh JW; Pennica D; Levine AJ WISP-1 is a Wnt-1-and beta-catenin-responsive oncogene | 67 | 38
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65 | 7 | 438 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 18(5):991-996
Saitoh T; Hirai M; Katoh M Molecular cloning and characterization of human Frizzled-8 gene on chromosome 10p11.2 | 67 | 7
|
66 | 5 | 71 1999 EXPERIMENTAL CELL RESEARCH 253(1):63-77
Dang CV; Resar LMS; Emison E; Kim S; Li Q; Prescott JE; Wonsey D; Zeller K Function of the c-Myc oncogenic transcription factor | 66 | 2
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67 | 1 | 93 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(42):29583-29586
Fry CJ; Farnham PJ Context-dependent transcriptional regulation | 66 | 1
|
68 | 8 | 441 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(1):111-115
Kirikoshi H; Sekihara H; Katoh M Up-regulation of Frizzled-7 (FZD7) in human gastric cancer | 66 | 3
|
69 | 3 | 65 1999 EMBO JOURNAL 18(11):3054-3063
Damalas A; Ben-Ze'ev A; Simcha I; Shtutman N; Leal JFN; Zhurinsky J; Geiger B; Oren M Excess beta-catenin promotes accumulation of transcriptionally active p53 | 65 | 24
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70 | 2 | 543 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(3):992-999
Chen CR; Kang YB; Massague J Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program | 64 | 5
|
71 | 5 | 110 1999 MOLECULAR AND CELLULAR BIOLOGY 19(8):5696-5706
Kolligs FT; Hu G; Dang CV; Fearon ER Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression | 62 | 38
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72 | 6 | 440 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(1):105-110
Saitoh T; Hirai M; Katoh M Molecular cloning and characterization of human Frizzled-5 gene on chromosome 2q33.3-q34 region | 62 | 2
|
73 | 3 | 303 2000 NATURE GENETICS 26(3):291-299
Jacobs JJL; Keblusek P; Robanus-Maandag E; Kristel P; Lingbeek M; Nederlof PM; van Welsem T; van de Vijver MJ; Koh EY; Daley GQ; van Lohuizen M Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers | 61 | 0
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74 | 9 | 347 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 284(5):1168-1175
Saitoh T; Hirai M; Katoh M Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region | 61 | 2
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75 | 23 | 429 2001 HUMAN MOLECULAR GENETICS 10(7):721-733
Fearnhead NS; Britton MP; Bodmer WF The ABC of APC | 61 | 12
|
76 | 3 | 224 2000 EUROPEAN JOURNAL OF CANCER 36(5):664-674
Smith ML; Hawcroft G; Hull MA The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action | 60 | 4
|
77 | 6 | 346 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 283(4):798-805
Kirikoshi H; Sekihara H; Katoh M WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells | 60 | 2
|
78 | 1 | 132 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(1):139-144
Aoki M; Hecht A; Kruse U; Kemler R; Vogt PK Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1 | 59 | 27
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79 | 9 | 442 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(1):123-127
Saitoh T; Katoh M Molecular cloning and characterization of human WNT8A | 59 | 2
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80 | 13 | 600 2002 CELL 111(2):241-250
van de Wetering M; Sancho E; Verweij C; de Lau W; Oving I; Hurlstone A; van der Horn K; Batlle E; Coudreuse D; Haramis AP; Tion-Pon-Fong M; Moerer P; van den Born M; Soete G; Pals S; Eilers M; Medema R; Clevers H The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells | 59 | 0
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81 | 5 | 275 2000 JOURNAL OF CELL BIOLOGY 148(3):567-578
Huelsken J; Vogel R; Brinkmann V; Erdmann B; Birchmeier C; Birchmeier W Requirement for beta-catenin in anterior-posterior axis formation in mice | 58 | 14
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82 | 3 | 170 2000 BLOOD 96(6):2206-2214
Hashimoto S; Suzuki T; Nagai S; Yamashita T; Toyoda N; Matsushima K Identification of genes specifically expressed in human activated and mature dendritic cells through serial analysis of gene expression | 57 | 2
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83 | 29 | 281 2000 JOURNAL OF CELL SCIENCE 113(18):3127-3139
Zhurinsky J; Shtutman M; Ben-Ze'ev A Plakoglobin and beta-catenin: protein interactions, regulation and biological roles | 57 | 18
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84 | 2 | 61 1999 DEVELOPMENT 126(10):2285-2298
Zhu AJ; Watt FM beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion | 56 | 20
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85 | 1 | 136 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(20):11566-11571
Jayachandra S; Low KG; Thlick AE; Yu J; Ling PD; Chang Y; Moore PS Three unrelated viral transforming proteins (vIRF, EBNA2, and E1A) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors (Retracted article. See vol 98, pg 12313, 2001) | 55 | 2
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86 | 8 | 515 2001 NATURE GENETICS 28(1):53-57
Hovanes K; Li TWH; Munguia JE; Truong T; Milovanovic T; Marsh JL; Holcombe RF; Waterman ML beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer | 55 | 26
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87 | 4 | 345 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 281(3):815-820
Saitoh T; Moriwaki J; Koike J; Takagi A; Miwa T; Shiokawa K; Katoh M Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway | 54 | 4
|
88 | 5 | 21 1999 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1424(2-3):M23-M37
Roose J; Clevers H TCF transcription factors: molecular switches in carcinogenesis | 53 | 0
|
89 | 3 | 293 2000 MOLECULAR AND CELLULAR BIOLOGY 20(10):3497-3509
Santoni-Rugiu E; Falck J; Mailand N; Bartek J; Lukas J Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway | 53 | 0
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90 | 3 | 332 2000 TRENDS IN GENETICS 16(10):423-425
Velculescu VE; Vogelstein B; Kinzler KW Analysing uncharted transcriptomes with SAGE | 53 | 3
|
91 | 1 | 68 1999 EUROPEAN JOURNAL OF CANCER 35(3):335-351
Ilyas M; Straub J; Tomlinson IPM; Bodmer WF Genetic pathways in colorectal and other cancers | 52 | 8
|
92 | 4 | 267 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(31):23790-23797
Song DH; Sussman DJ; Seldin DC Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells | 51 | 8
|
93 | 10 | 284 2000 JOURNAL OF CLINICAL ONCOLOGY 18(9):1967-1979
Goss KH; Groden J Biology of the adenomatous polyposis coli tumor suppressor | 50 | 15
|
94 | 15 | 327 2000 SEMINARS IN CANCER BIOLOGY 10(3):185-200
Buendia MA Genetics of hepatocellular carcinoma | 50 | 9
|
95 | 5 | 406 2001 EMBO JOURNAL 20(17):4935-4943
Barker N; Hurlstone A; Musisi H; Miles A; Bienz M; Clevers H The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation | 50 | 22
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96 | 4 | 162 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 269(1):103-109
Koike J; Sagara N; Kirikoshi H; Takagi A; Miwa T; Hirai M; Katoh M Molecular cloning and genomic structure of the beta TRCP2 gene on chromosome 5q35.1 | 49 | 8
|
97 | 7 | 180 2000 CANCER RESEARCH 60(13):3338-3342
Thompson WJ; Piazza GA; Li H; Liu L; Fetter J; Zhu B; Sperl G; Ahnen D; Pamukcu R Exisulind induction of apoptosis involves guanosine 3 ',5 '-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin | 49 | 3
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98 | 5 | 247 2000 IMMUNITY 13(1):15-24
Reya T; O'Riordan M; Okamura R; Devaney E; Willert K; Nusse R; Grosschedl R Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism | 49 | 11
|
99 | 2 | 311 2000 ONCOGENE 19(8):1102-1113
Sternlicht MD; Bissell MJ; Werb Z The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter | 49 | 0
|
100 | 1 | 42 1999 CELL 99(4):399-408
Kim L; Liu JC; Kimmel AR The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification | 48 | 6
|
# | Cited nodes | Nodes / Authors | GCS | LCS |
101 | 12 | 172 2000 BRITISH JOURNAL OF SURGERY 87(8):992-1005
Wijnhoven BPL; Dinjens WNM; Pignatelli M E-cadherin-catenin cell-cell adhesion complex and human cancer | 48 | 5
|
102 | 1 | 76 1999 GENOME RESEARCH 9(10):950-959
Ewing RM; Ben Kahla A; Poirot O; Lopez F; Audic S; Claverie JM Large-scale statistical analyses of rice ESTs reveal correlated patterns of gene expression | 47 | 0
|
103 | 1 | 79 1999 HEPATOLOGY 29(4):1208-1214
Zimonjic DB; Keck CL; Thorgeirsson SS; Popescu NC Novel recurrent genetic imbalances in human hepatocellular carcinoma cell lines identified by comparative genomic hybridization | 47 | 1
|
104 | 2 | 191 2000 CARCINOGENESIS 21(3):469-476
Bach SP; Renehan AG; Potten CS Stem cells: the intestinal stem cell as a paradigm | 47 | 2
|
105 | 10 | 468 2001 JOURNAL OF CELL BIOLOGY 153(5):1049-1059
Gottardi CJ; Wong E; Gumbiner BM E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner | 47 | 13
|
106 | 2 | 113 1999 NATURE CELL BIOLOGY 1(3):144-151
Yu X; Waltzer L; Bienz M A new Drosophila APC homologue associated with adhesive zones of epithelial cells | 46 | 13
|
107 | 2 | 300 2000 NATURE 406(6798):897-902
Sasaki T; Irie-Sasaki J; Horie Y; Bachmaier K; Fata JE; Li M; Suzuki A; Bouchard D; Ho A; Redston M; Gallinger S; Khokha R; Mak TW; Hawkins PT; Stephens L; Scherer SW; Tsao M; Penninger JM Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)K gamma | 46 | 4
|
108 | 5 | 309 2000 ONCOGENE 19(4):537-545
Ikeda S; Kishida M; Matsuura Y; Usui H; Kikuchi A GSK-3 beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin | 46 | 21
|
109 | 5 | 437 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 18(5):959-964
Saitoh T; Katoh M Expression profiles of beta TRCP1 and beta TRCP2, and mutation analysis of beta TRCP2 in gastric cancer | 46 | 6
|
110 | 16 | 518 2001 NATURE REVIEWS CANCER 1(1):55-67
Fodde R; Smits R; Clevers H APC, signal transduction and genetic instability in colorectal cancer | 46 | 5
|
111 | 16 | 168 2000 BIOESSAYS 22(11):961-965
Barker N; Clevers H Catenins, Wnt signaling and cancer | 45 | 20
|
112 | 13 | 206 2000 COLORECTAL CANCER: NEW ASPECTS OF MOLECULAR BIOLOGY AND IMMUNOLOGY AND THEIR CLINICAL APPLICATIONS 910():21-35
Behrens J Control of beta-catenin signaling in tumor development | 45 | 12
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113 | 7 | 262 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(23):17894-17899
Chen RH; Ding WV; McCormick F Wnt signaling to beta-catenin involves two interactive components - Glycogen synthase kinase-3 beta inhibition and activation of protein kinase C | 45 | 12
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114 | 3 | 544 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2598-2603
Park BH; Vogelstein B; Kinzler KW Genetic disruption of PPAR delta decreases the tumorigenicity of human colon cancer cells | 45 | 3
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115 | 4 | 213 2000 DEVELOPMENT 127(3):469-482
Galceran J; Miyashita-Lin EM; Devaney E; Rubenstein JLR; Grosschedl R Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1 | 44 | 3
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116 | 6 | 278 2000 JOURNAL OF CELL BIOLOGY 149(4):761-766
Tirnauer JS; Bierer BE EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability | 44 | 3
|
117 | 2 | 35 1999 CANCER RESEARCH 59(16):3880-3882
Koesters R; Ridder R; Kopp-Schneider A; Betts D; Adams V; Niggli F; Briner J; Doeberitz MV Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors | 43 | 17
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118 | 5 | 137 1999 PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY 72(3):299-328
Craig KL; Tyers M The F-box: a new motif for ubiquitin dependent proteolysis in cell cycle regulation and signal transduction | 43 | 0
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119 | 7 | 154 2000 AMERICAN JOURNAL OF PATHOLOGY 156(3):865-870
Brabletz T; Herrmann K; Jung A; Faller G; Kirchner T Expression of nuclear beta-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas | 43 | 24
|
120 | 10 | 214 2000 DEVELOPMENT 127(17):3805-3813
Lickert H; Domon C; Huls G; Wehrle C; Duluc I; Clevers H; Meyer BI; Freund JN; Kemler R Wnt/beta-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine | 43 | 6
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121 | 4 | 238 2000 GENES CHROMOSOMES & CANCER 28(4):443-453
Webster MT; Rozycka M; Sara E; Davis E; Smalley M; Young N; Dale TC; Wooster R Sequence variants of the axin gene in breast, colon, and other cancers: An analysis of mutations that interfere with GSK3 binding | 43 | 20
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122 | 1 | 43 1999 CELL GROWTH & DIFFERENTIATION 10(6):369-376
Caca K; Kolligs FT; Ji XD; Hayes M; Qian JM; Yahanda A; Rimm DL; Costa J; Fearon ER beta- and gamma-catenin mutations, but not E-cadherin inactivation, underlie T-cell factor lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer | 42 | 23
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123 | 1 | 67 1999 ENDOCRINE REVIEWS 20(2):207-239
Potter E; Bergwitz C; Brabant G The cadherin-catenin system: Implications for growth and differentiation of endocrine tissues | 42 | 7
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124 | 1 | 100 1999 JOURNAL OF CLINICAL PATHOLOGY 52(8):555-568
Michalides RJAM Cell cycle regulators: mechanisms and their role in aetiology, prognosis, and treatment of cancer | 42 | 0
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125 | 7 | 161 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 268(2):243-248
Kikuchi A Regulation of beta-catenin signaling in the Wnt pathway | 42 | 15
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126 | 4 | 177 2000 CANCER RESEARCH 60(6):1671-1676
Shih IM; Tu J; He TC; Vogelstein B; Kinzler KW The beta-catenin binding domain of adenomatous polyposis coil is sufficient for tumor suppression | 42 | 23
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127 | 6 | 47 1999 CELLULAR AND MOLECULAR LIFE SCIENCES 56(5-6):523-537
Novak A; Dedhar S Signaling through beta-catenin and Lef/Tcf | 41 | 7
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128 | 4 | 283 2000 JOURNAL OF CLINICAL INVESTIGATION 106(4):533-539
Koh TJ; Bulitta CJ; Fleming JV; Dockray GJ; Varro A; Wang TC Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis | 41 | 23
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129 | 8 | 443 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(2):311-315
Saitoh T; Katoh M FRAT1 and FRAT2, clustered in human chromosome 10q24.1 region, are up-regulated in gastric cancer | 41 | 2
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130 | 2 | 273 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(45):35170-35175
Miyagishi M; Fujii R; Hatta M; Yoshida E; Araya N; Nagafuchi A; Ishihara S; Nakajima T; Fukamizu A Regulation of Lef-mediated transcription and p53-dependent pathway by associating beta-catenin with CBP/p300 | 40 | 13
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131 | 7 | 48 1999 CELLULAR SIGNALLING 11(11):777-788
Kikuchi A Roles of axin in the Wnt signalling pathway | 39 | 13
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132 | 1 | 148 1999 TRENDS IN GENETICS 15(3):109-112
Greider CW Telomerase activation - one step on the road to cancer? | 39 | 0
|
133 | 3 | 323 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(22):12103-12108
Playford MP; Bicknell D; Bodmer WF; Macaulay VM Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin | 39 | 9
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134 | 5 | 351 2001 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1471(3):M135-M145
Amati B; Frank SR; Donjerkovic D; Taubert S Function of the c-Myc oncoprotein in chromatin remodeling and transcription | 39 | 0
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135 | 7 | 466 2001 JOURNAL OF CELL BIOLOGY 152(4):785-794
Soriano S; Kang DE; Fu MF; Pestell R; Chevallier N; Zheng H; Koo EH Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and Notch processing | 39 | 4
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136 | 4 | 521 2001 NUCLEIC ACIDS RESEARCH 29(7):1410-1419
Brantjes H; Roose J; van de Wetering M; Clevers H All Tcf HMG box transcription factors interact with Groucho-related co-repressors | 39 | 12
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137 | 6 | 415 2001 EXPERIMENTAL CELL RESEARCH 264(1):169-184
Elenbaas B; Weinberg RA Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation | 38 | 1
|
138 | 17 | 689 2002 JOURNAL OF CLINICAL INVESTIGATION 109(8):987-991
Conacci-Sorrell M; Zhurinsky J; Ben-Ze'ev A The cadherin-catenin adhesion system in signaling and cancer | 38 | 0
|
139 | 1 | 9 1999 AMERICAN JOURNAL OF PATHOLOGY 154(2):515-523
Wielenga VJM; Smits R; Korinek V; Smit L; Kielman M; Fodde R; Clevers H; Pals ST Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway | 37 | 21
|
140 | 1 | 55 1999 CURRENT BIOLOGY 9(2):105-108
van Es JH; Kirkpatrick C; van de Wetering M; Molenaar M; Miles A; Kuipers J; Destree O; Peifer M; Clevers H Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor | 37 | 0
|
141 | 1 | 134 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(5):2322-2326
Laken SJ; Papadopoulos N; Petersen GM; Gruber SB; Hamilton SR; Giardiello FM; Brensinger JD; Vogelstein B; Kinzler KW Analysis of masked mutations in familial adenomatous polyposis | 37 | 6
|
142 | 2 | 158 2000 ANTICANCER RESEARCH 20(1A):407-416
Page C; Lin HJ; Jin Y; Castle VP; Nunez G; Huang M; Lin JY Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis | 37 | 0
|
143 | 5 | 257 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(6):4374-4382
Uren A; Reichsman F; Anest V; Taylor WG; Muraiso K; Bottaro DP; Cumberledge S; Rubin JS Secreted frizzled-related protein-1 binds directly to wingless and is a biphasic modulator of Wnt signaling | 37 | 7
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144 | 11 | 469 2001 JOURNAL OF CELL BIOLOGY 153(6):1161-1173
Persad S; Troussard AA; McPhee TR; Mulholland DJ; Dedhar S Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation | 37 | 4
|
145 | 1 | 78 1999 GUT 45(5):730-732
Dimberg J; Samuelsson A; Hugander A; Soderkvist P Differential expression of cyclooxygenase 2 in human colorectal cancer | 36 | 2
|
146 | 1 | 118 1999 ONCOGENE 18(15):2507-2517
Rosenwald IB; Chen JJ; Wang ST; Savas L; London IM; Pullman J Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis | 36 | 2
|
147 | 1 | 122 1999 ONCOGENE 18(33):4726-4733
Devereux TR; Anna CH; Foley JF; White CM; Sills RC; Barrett JC Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis | 36 | 10
|
148 | 1 | 73 1999 GENE 238(2):301-313
Krupnik VE; Sharp JD; Jiang C; Robison K; Chickering TW; Amaravadi L; Brown DE; Guyot D; Mays G; Leiby K; Chang B; Duong T; Goodearl ADJ; Gearing DP; Sokol SY; McCarthy SA Functional and structural diversity of the human Dickkopf gene family | 35 | 1
|
149 | 4 | 179 2000 CANCER RESEARCH 60(13):3323-3327
Yamada Y; Yoshimi N; Hirose Y; Kawabata K; Matsunaga K; Shimizu M; Hara A; Mori H Frequent beta-catenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis | 35 | 8
|
150 | 4 | 209 2000 CURRENT OPINION IN GENETICS & DEVELOPMENT 10(1):81-93
Macleod K Tumor suppressor genes | 35 | 2
|
151 | 14 | 294 2000 MOLECULAR AND CELLULAR BIOLOGY 20(12):4238-4252
Zhurinsky J; Shtutman M; Ben-Ze'ev A Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin | 35 | 18
|
152 | 18 | 464 2001 JOURNAL OF CELL BIOLOGY 152(1):87-96
Chen SQ; Guttridge DC; You ZB; Zhang ZC; Fribley A; Mayo MW; Kitajewski J; Wang CY Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription | 35 | 13
|
153 | 10 | 503 2001 MOLECULAR AND CELLULAR BIOLOGY 21(4):1370-1383
Crawford HC; Fingleton B; Gustavson MD; Kurpios N; Wagenaar RA; Hassell JA; Matrisian LM The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors | 35 | 6
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154 | 5 | 522 2001 ONCOGENE 20(1):133-140
Tan C; Costello P; Sanghera J; Dominguez D; Baulida J; de Herreros AG; Dedhar S Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells | 35 | 7
|
155 | 3 | 231 2000 GENES & DEVELOPMENT 14(2):158-162
Dorsky RI; Raible DW; Moon RT Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway | 34 | 3
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156 | 2 | 274 2000 JOURNAL OF CELL BIOLOGY 148(1):173-187
Eger A; Stockinger A; Schaffhauser B; Beug H; Foisner R Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity | 34 | 10
|
157 | 4 | 277 2000 JOURNAL OF CELL BIOLOGY 149(2):503-519
Charpentier E; Lavker RM; Acquista E; Cowin P Plakoglobin suppresses epithelial proliferation and hair growth in vivo. | 34 | 11
|
158 | 11 | 295 2000 MOLECULAR BIOLOGY OF THE CELL 11(10):3509-3523
Kim K; Pang KM; Evans M; Hay ED Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators | 34 | 17
|
159 | 4 | 493 2001 MEDICINAL RESEARCH REVIEWS 21(4):245-273
Myung J; Kim KB; Crews CM The ubiquitin-proteasome pathway and proteasome inhibitors | 34 | 0
|
160 | 11 | 26 1999 CANCER AND METASTASIS REVIEWS 18(2):215-230
Smalley MJ; Dale TC Wnt signalling in mammalian development and cancer | 33 | 13
|
161 | 1 | 111 1999 MOLECULAR MEDICINE TODAY 5(4):172-177
Guilford P E-cadherin downregulation in cancer: fuel on the fire? | 33 | 2
|
162 | 1 | 117 1999 ONCOGENE 18(10):1903-1910
Ugolini F; Adelaide J; Charafe-Jauffret E; Nguyen C; Jacquemier J; Jordan B; Birnbaum D; Pebusque MJ Differential expression assay of chromosome arm 8p genes identifies Frizzled-related (FRP1/FRZB) and Fibroblast Growth Factor Receptor 1 (FGFR1) as candidate breast cancer genes | 33 | 7
|
163 | 6 | 215 2000 DEVELOPMENTAL BIOLOGY 219(1):98-114
Widelitz RB; Jiang TX; Lu JF; Chuong CM beta-catenin in epithelial morphogenesis: Conversion of part of avian foot scales into feather buds with a mutated beta-catenin | 33 | 2
|
164 | 3 | 226 2000 EUROPEAN JOURNAL OF CANCER 36(13):1607-1620
Beavon IRG The E-cadherin-catenin complex in tumour metastasis: structure, function and regulation | 33 | 6
|
165 | 1 | 307 2000 NUCLEIC ACIDS RESEARCH 28(15):2969-2976
Shie JL; Chen ZY; Fu MF; Pestell RG; Tseng CC Gut-enriched Kruppel-like factor represses cyclin D1 promoter activity through Sp1 motif | 33 | 3
|
166 | 13 | 405 2001 EMBO JOURNAL 20(17):4912-4922
Damalas A; Kahan S; Shtutman M; Ben-Ze'ev A; Oren M Deregulated beta-catenin induces a p53-and ARF-dependent growth arrest and cooperates with Ras in transformation | 33 | 12
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167 | 26 | 555 2002 AMERICAN JOURNAL OF PATHOLOGY 160(2):389-401
Wong NACS; Pignatelli M beta-catenin - A linchpin in colorectal carcinogenesis? | 33 | 5
|
168 | 1 | 89 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(23):16641-16645
Easwaran V; Song V; Polakis P; Byers S The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of beta-catenin-lymphocyte enhancer-binding factor signaling | 32 | 13
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169 | 2 | 127 1999 ONCOGENE 18(47):6583-6588
Terris B; Pineau P; Bregeaud L; Valla D; Belghiti J; Tiollais P; Degott C; Dejean A Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas | 32 | 13
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170 | 5 | 182 2000 CANCER RESEARCH 60(14):3872-3879
Duval A; Rolland S; Tubacher E; Bui H; Thomas G; Hamelin R The human T-cell transcription factor-4 gene: Structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines | 32 | 15
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171 | 5 | 218 2000 EMBO JOURNAL 19(21):5813-5823
Beier R; Burgin A; Kiermaier A; Fero M; Karsunky H; Saffrich R; Moroy T; Ansorge W; Roberts J; Eilers M Induction of cyclin E-cdk2 kinase activity, E2F-dependent transcription and cell growth by Myc are genetically separable events | 32 | 2
|
172 | 2 | 349 2001 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1519(1-2):13-29
Reeves R; Beckerbauer L HMGI/Y proteins: flexible regulators of transcription and chromatin structure | 32 | 1
|
173 | 7 | 417 2001 FEBS LETTERS 490(3):153-162
Nasi S; Ciarapica R; Jucker R; Rosati J; Soucek L Making decisions through Myc | 32 | 0
|
174 | 2 | 82 1999 IMMUNITY 11(4):433-442
Held W; Kunz B; Lowin-Kropf B; van de Wetering M; Clevers H Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1 | 31 | 2
|
175 | 1 | 124 1999 ONCOGENE 18(35):5010-5014
da Costa LT; He TC; Yu J; Sparks AB; Morin PJ; Polyak K; Laken S; Vogelstein B; Kinzler KW CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling | 31 | 0
|
176 | 4 | 290 2000 MECHANISMS OF DEVELOPMENT 91(1-2):249-258
Arnold SJ; Stappert J; Bauer A; Kispert A; Herrmann BG; Kemler R Brachyury is a target gene of the Wnt/beta-catenin signaling pathway | 31 | 4
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177 | 3 | 306 2000 NUCLEIC ACIDS RESEARCH 28(2):446-453
Greasley PJ; Bonnard C; Amati B Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis | 31 | 3
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178 | 21 | 471 2001 JOURNAL OF CELL BIOLOGY 154(6):1185-1196
Stockinger A; Eger A; Wolf J; Beug H; Foisner R E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity | 31 | 5
|
179 | 13 | 514 2001 NATURE CELL BIOLOGY 3(9):793-801
Ryo A; Nakamura M; Wulf G; Liou YC; Lu KP Pin 1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC | 31 | 9
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180 | 1 | 107 1999 MELANOMA RESEARCH 9(5):421-432
Castellano M; Parmiani G Genes involved in melanoma: overview of INK4a and other loci | 30 | 1
|
181 | 5 | 265 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(28):21435-21443
Ilan N; Cheung L; Pinter E; Madri JA Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation | 30 | 1
|
182 | 3 | 526 2001 ONCOGENE 20(25):3247-3257
Landesman-Bollag E; Romieu-Mourez R; Song DH; Sonenshein GE; Cardiff RD; Seldin DC Protein kinase CK2 in mammary gland tumorigenesis | 30 | 0
|
183 | 13 | 546 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(18):10356-10361
Brabletz T; Jung A; Reu S; Porzner M; Hlubek F; Kunz-Schughart LA; Knuechel R; Kirchner T Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment | 30 | 9
|
184 | 2 | 756 2002 SCIENCE 295(5560):1726-1729
Velcich A; Yang WC; Heyer J; Fragale A; Nicholas C; Viani S; Kucherlapati R; Lipkin M; Yang K; Augenlicht L Colorectal cancer in mice genetically deficient in the mucin Muc2 | 30 | 3
|
185 | 1 | 38 1999 CARCINOGENESIS 20(4):635-640
McEntee MF; Chiu CH; Whelan J Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice | 29 | 9
|
186 | 1 | 84 1999 INTERNATIONAL JOURNAL OF CANCER 82(5):625-629
Wright K; Wilson P; Morland S; Campbell I; Walsh M; Hurst T; Ward B; Cummings M; Chenevix-Trench G beta-catenin mutation and expression analysis in ovarian cancer: Exon 3 mutations and nuclear translocation in 16% of endometrioid tumours | 29 | 15
|
187 | 4 | 219 2000 EMBO REPORTS 1(6):519-523
Neufeld KL; Zhang F; Cullen BR; White RL APC-mediated downregulation of beta-catenin activity involves nuclear sequestration and nuclear export | 29 | 10
|
188 | 2 | 253 2000 INTERNATIONAL JOURNAL OF CANCER 89(2):172-176
Latil A; Vidaud D; Valeri A; Fournier G; Vidaud M; Lidereau R; Cussenot O; Bieche I htert expression correlates with myc over-expression in human prostate cancer | 29 | 0
|
189 | 2 | 266 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(29):21797-21800
Osthus RC; Shim H; Kim S; Li Q; Reddy R; Mukherjee M; Xu Y; Wonsey D; Lee LA; Dang CV Accelerated publication - Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc | 29 | 3
|
190 | 15 | 552 2001 VIRCHOWS ARCHIV 439(6):725-751
Van Aken E; De Wever O; da Rocha ASC; Mareel M Defective E-cadherin/catenin complexes in human cancer | 29 | 0
|
191 | 1 | 5 1998 CURRENT OPINION IN CELL BIOLOGY 10(6):702-709
Stappenbeck TS; Wong MH; Saam JR; Mysorekar IU; Gordon JI Notes from some crypt watchers: regulation of renewal in the mouse intestinal epithelium | 28 | 3
|
192 | 1 | 33 1999 CANCER RESEARCH 59(8):1830-1833
Ogawa K; Yamada Y; Kishibe K; Ishizaki K; Tokusashi Y beta-Catenin mutations are frequent in hepatocellular carcinomas but absent in adenomas induced by diethylnitrosamine in B6C3F1 mice | 28 | 7
|
193 | 1 | 45 1999 CELL GROWTH & DIFFERENTIATION 10(10):713-720
Bordonaro M; Mariadason JM; Aslam F; Heerdt BG; Augenlicht LH Butyrate-induced apoptotic cascade in colonic carcinoma cells: Modulation of the beta-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin a but not curcumin | 28 | 9
|
194 | 4 | 92 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(39):27682-27688
Kodama S; Ikeda S; Asahara T; Kishida M; Kikuchi A Axin directly interacts with plakoglobin and regulates its stability | 28 | 20
|
195 | 2 | 95 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(49):35247-35254
Zhang Y; Neo SY; Wang XH; Han JH; Lin SC Axin forms a complex with MEKK1 and activates c-Jun NH2-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling | 28 | 8
|
196 | 1 | 308 2000 ONCOGENE 19(3):365-372
Ishidate T; Matsumine A; Toyoshima K; Akiyama T The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase | 28 | 8
|
197 | 4 | 370 2001 CANCER RESEARCH 61(8):3465-3471
Mariadason JM; Bordonaro M; Aslam F; Shi L; Kuraguchi M; Velcich A; Augenlicht LH Down-regulation of beta-catenin TCF signaling is linked to colonic epithelial cell differentiation | 28 | 15
|
198 | 11 | 467 2001 JOURNAL OF CELL BIOLOGY 153(3):555-568
Imbert A; Eelkema R; Jordan S; Feiner H; Cowin P Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland | 28 | 12
|
199 | 8 | 479 2001 JOURNAL OF IMMUNOLOGY 166(7):4713-4720
Monick MM; Carter AB; Robeff PK; Flaherty DM; Peterson MW; Hunninghake GW Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin | 28 | 2
|
200 | 12 | 531 2001 ONCOGENE 20(40):5595-5610
Boxer LM; Dang CV Translocations involving c-myc and c-myc function | 28 | 2
|
# | Cited nodes | Nodes / Authors | GCS | LCS |
201 | 1 | 144 1999 SEMINARS IN LIVER DISEASE 19(3):253-262
Chen PJ; Chen DS Hepatitis B virus infection and hepatocellular carcinoma: Molecular genetics and clinical perspectives | 27 | 0
|
202 | 1 | 149 1999 UROLOGY 53(4):707-713
De Marzo AM; Knudsen B; Chan-Tack K; Epstein JI E-cadherin expression as a marker of tumor aggressiveness in routinely processed radical prostatectomy specimens | 27 | 0
|
203 | 4 | 171 2000 BRITISH JOURNAL OF CANCER 83(1):1-5
Compagni A; Christofori G Recent advances in research on multistage tumorigenesis | 27 | 1
|
204 | 8 | 217 2000 EMBO JOURNAL 19(10):2270-2279
Spink KE; Polakis P; Weis WI Structural basis of the Axin-adenomatous polyposis coli interaction | 27 | 5
|
205 | 10 | 414 2001 EXPERIMENTAL CELL RESEARCH 264(1):126-134
van Es JH; Giles RH; Clevers HC The many faces of the tumor suppressor gene APC | 27 | 0
|
206 | 12 | 422 2001 GENES & DEVELOPMENT 15(14):1796-1807
Tao WK; Pennica D; Xu LF; Kalejta RF; Levine AJ Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1 | 27 | 2
|
207 | 13 | 451 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(23):20436-20443
Piedra J; Martinez D; Castano J; Miravet S; Dunach M; de Herreros AG Regulation of beta-catenin structure and activity by tyrosine phosphorylation | 27 | 9
|
208 | 15 | 608 2002 DEVELOPMENTAL BIOLOGY 244(1):1-8
van Noort M; Clevers H TCF transcription factors, mediators of Wnt-signaling in development and cancer | 27 | 0
|
209 | 6 | 146 1999 TRENDS IN CELL BIOLOGY 9(12):M53-M56
McCormick F Signalling networks that cause cancer (Reprinted from Trends in Biochemical Science, vol 12, Dec., 1999) | 26 | 0
|
210 | 3 | 186 2000 CANCER RESEARCH 60(22):6318-6325
Mitchell KO; Ricci MS; Miyashita T; Dicker DT; Jin ZY; Reed JC; El-Deiry WS Bax is a transcriptional target and mediator of c-Myc-induced apoptosis | 26 | 1
|
211 | 2 | 192 2000 CARCINOGENESIS 21(6):1167-1173
Mutanen M; Pajari AM; Oikarinen SI Beef induces and rye bran prevents the formation of intestinal polyps in Apc(Min) mice: relation to beta-catenin and PKC isozymes | 26 | 2
|
212 | 1 | 242 2000 GUT 47(6):820-824
Smith AM; Watson SA Gastrin and gastrin receptor activation: an early event in the adenoma-carcinoma sequence | 26 | 1
|
213 | 6 | 310 2000 ONCOGENE 19(8):1002-1009
Li Y; Hively WP; Varmus HE Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer | 26 | 9
|
214 | 8 | 450 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(23):20108-20115
Howe LR; Crawford HC; Subbaramaiah K; Hassell JA; Dannenberg AJ; Brown AMC PEA3 is up-regulated in response to Wnt1 and activates the expression of cyclooxygenase-2 | 26 | 5
|
215 | 23 | 506 2001 MOLECULAR AND CELLULAR BIOLOGY 21(20):6768-6781
Sadot E; Geiger B; Oren M; Ben-Ze'ev A Down-regulation of beta-catenin by activated p53 | 26 | 8
|
216 | 8 | 547 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(19):10863-10868
Xia XF; Qian S; Soriano S; Wu Y; Fletcher AM; Wang XJ; Koo EH; Wu XW; Zheng H Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis | 26 | 7
|
217 | 13 | 607 2002 DEVELOPMENT 129(1):95-109
Niemann C; Owens DM; Hulsken J; Birchmeier W; Watt FM Expression of Delta NLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours | 26 | 6
|
218 | 2 | 661 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(1):854-861
Yagi K; Furuhashi M; Aoki H; Goto D; Kuwano H; Sugamura K; Miyazono K; Kato M c-myc is a downstream target of the Smad pathway | 26 | 3
|
219 | 3 | 87 1999 JAPANESE JOURNAL OF CANCER RESEARCH 90(12):1301-1309
Kondo Y; Kanai Y; Sakamoto M; Genda T; Mizokami M; Ueda R; Hirohashi S beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma | 25 | 12
|
220 | 3 | 125 1999 ONCOGENE 18(38):5325-5333
Heyer J; Yang K; Lipkin M; Edelmann W; Kucherlapati R Mouse models for colorectal cancer | 25 | 6
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221 | 5 | 259 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(15):10905-10911
Hakimelahi S; Parker HR; Gilchrist AJ; Barry M; Li Z; Bleackley RC; Pasdar M Plakoglobin regulates the expression of the anti-apoptotic protein BCL-2 | 25 | 8
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222 | 4 | 260 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(19):14736-14742
Rimerman RA; Gellert-Randleman A; Diehl JA Wnt1 and MEK1 cooperate to promote cyclin D1 accumulation and cellular transformation | 25 | 3
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223 | 4 | 365 2001 CANCER RESEARCH 61(5):1874-1878
Yamada Y; Yoshimi N; Hirose Y; Matsunaga K; Katayama M; Sakata K; Shimizu M; Kuno T; Mori H Sequential analysis of morphological and biological properties of beta-catenin-accumulated crypts, provable premalignant lesions independent of aberrant crypt foci in rat colon carcinogenesis | 25 | 7
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224 | 7 | 418 2001 FEBS LETTERS 490(3):179-189
DeSalle LM; Pagano M Regulation of the G1 to S transition by the ubiquitin pathway | 25 | 0
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225 | 17 | 652 2002 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 10(6):677-682
Katoh M Paradigm shift in gene-finding method: From bench-top approach to desk-top approach (review) | 25 | 0
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226 | 12 | 212 2000 CYTOKINE & GROWTH FACTOR REVIEWS 11(4):273-282
Akiyama T Wnt/beta-catenin signaling | 24 | 6
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227 | 23 | 227 2000 EXPERIMENTAL CELL RESEARCH 261(1):75-82
Ben-Ze'ev A; Shtutman M; Zhurinsky J The integration of cell adhesion with gene expression: The role of beta-catenin | 24 | 0
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228 | 7 | 476 2001 JOURNAL OF CLINICAL ONCOLOGY 19(11):2948-2958
Polyak K; Riggins GJ Gene discovery using the serial analysis of gene expression technique: Implications for cancer research | 24 | 2
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229 | 1 | 516 2001 NATURE GENETICS 28(2):165-168
Waikel RL; Kawachi Y; Waikel PA; Wang XJ; Roop DR Deregulated expression of c-Myc depletes epidermal stem cells | 24 | 5
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230 | 1 | 64 1999 DIGESTION 60(6):544-548
Gerdes B; Ramaswamy A; Simon B; Pietsch T; Bastian D; Kersting M; Moll R; Bartsch D Analysis of beta-catenin gene mutations in pancreatic tumors | 23 | 10
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231 | 1 | 72 1999 EXPERIMENTAL CELL RESEARCH 253(2):336-348
Uusitalo M; Heikkila M; Vainio S Molecular genetic studies of Wnt signaling in the mouse | 23 | 0
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232 | 1 | 80 1999 HUMAN MOLECULAR GENETICS 8(8):1479-1485
Smith DP; Spicer J; Smith A; Swift S; Ashworth A The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase | 23 | 0
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233 | 2 | 128 1999 ONCOGENE 18(48):6806-6809
Duval A; Iacopetta B; Ranzani GN; Lothe RA; Thomas G; Hamelin R Variable mutation frequencies in coding repeats of TCF-4 and other target genes in colon, gastric and endometrial carcinoma showing microsatellite instability | 23 | 8
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234 | 1 | 258 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(12):8369-8374
Kawahara K; Morishita T; Nakamura T; Hamada F; Toyoshima K; Akiyama T Down-regulation of beta-catenin by the colorectal tumor suppressor APC requires association with axin and beta-catenin | 23 | 10
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235 | 5 | 288 2000 JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 59(4):333-337
Eberhart CG; Tihan T; Burger PC Nuclear localization and mutation of beta-catenin in medulloblastomas | 23 | 9
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236 | 8 | 398 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(1):19-26
Prober DA; Edgar BA Growth regulation by oncogenes - new insights from model organisms | 23 | 1
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237 | 1 | 501 2001 MOLECULAR AND CELLULAR BIOLOGY 21(2):575-594
Reeves R; Edberg DD; Li Y Architectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells | 23 | 2
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238 | 12 | 530 2001 ONCOGENE 20(37):5093-5099
Michaelson JS; Leder P beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland | 23 | 12
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239 | 1 | 53 1999 COLON CANCER PREVENTION 470():23-32
Polakis P; Hart M; Rubinfeld B Defects in the regulation of beta-catenin in colorectal cancer | 22 | 8
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240 | 2 | 69 1999 EUROPEAN JOURNAL OF CANCER 35(14):1986-2002
Ilyas M; Straub J; Tomlinson IPM; Bodmer WF Genetic pathways in colorectal and other cancers (Reprinted from Eur J Cancer, vol 35, pg 335-351, 1999) | 22 | 2
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241 | 1 | 106 1999 MECHANISMS OF DEVELOPMENT 81(1-2):65-74
Vleminckx K; Kemler R; Hecht A The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis | 22 | 8
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242 | 7 | 156 2000 AMERICAN JOURNAL OF PATHOLOGY 157(4):1113-1121
Kirchner T; Brabletz T Patterning and nuclear beta-catenin expression in the colonic adenoma-carcinoma sequence - Analogies with embryonic gastrulation | 22 | 11
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243 | 2 | 199 2000 CELL PROLIFERATION 33(1):1-18
Roncucci L; Pedroni M; Vaccina F; Benatti P; Marzona L; De Pol A Aberrant crypt foci in colorectal carcinogenesis. Cell and crypt dynamics | 22 | 1
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244 | 5 | 261 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(21):16345-16353
Steinhusen U; Badock V; Bauer A; Behrens J; Wittman-Liebold B; Dorken B; Bommert K Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential | 22 | 6
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245 | 6 | 465 2001 JOURNAL OF CELL BIOLOGY 152(3):491-502
Reinacher-Schick A; Gumbiner BM Apical membrane localization of the adenomatous polyposis coli tumor suppressor protein and subcellular distribution of the beta-catenin destruction complex in polarized epithelial cells | 22 | 0
|
246 | 6 | 517 2001 NATURE IMMUNOLOGY 2(8):691-697
Ioannidis V; Beermann F; Clevers H; Held W The beta-catenin-TCF-I pathway ensures CD4(+)CD8(+) thymocyte survival | 22 | 6
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247 | 2 | 549 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(26):15203-15208
Nacht M; Dracheva T; Gao YH; Fujii T; Chen YD; Player A; Akmaev V; Cook B; Dufault M; Zhang M; Zhang W; Guo MZ; Curran J; Han S; Sidransky D; Buetow K; Madden SL; Jen J Molecular characteristics of non-small cell lung cancer | 22 | 2
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248 | 13 | 716 2002 MOLECULAR AND CELLULAR BIOLOGY 22(4):1184-1193
Lustig B; Jerchow B; Sachs M; Weiler S; Pietsch T; Karsten U; van de Wetering M; Clevers H; Schlag PM; Birchmeier W; Behrens J Negative feedback loop of Wnt signaling through upregulation of conductin/Axin2 in colorectal and liver tumors | 22 | 10
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249 | 1 | 752 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(18):11593-11598
Siddiqui-Jain A; Grand CL; Bearss DJ; Hurley LH Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription | 22 | 0
|
250 | 1 | 198 2000 CELL GROWTH & DIFFERENTIATION 11(4):201-210
Ngo CV; Gee M; Akhtar N; Yu D; Volpert O; Auerbach R; Thomas-Tikhonenko A An in vivo function for the transforming Myc protein: Elicitation of the angiogenic phenotype | 21 | 1
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251 | 3 | 216 2000 DRUG DISCOVERY TODAY 5(9):415-425
Madden SL; Wang CJ; Landes G Serial analysis of gene expression: from gene discovery to target identification | 21 | 2
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252 | 2 | 240 2000 GLIA 32(2):146-154
Gunnersen JM; Spirkoska V; Smith PE; Danks RA; Tan SS Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression | 21 | 4
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253 | 4 | 271 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(41):32046-32051
Haertel-Wiesmann M; Liang YX; Fantl WJ; Williams LT Regulation of cyclooxygenase-2 and periostin by Wnt-3 in mouse mammary epithelial cells | 21 | 0
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254 | 14 | 272 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(44):34399-34406
Hinoi T; Yamamoto H; Kishida M; Takada S; Kishida S; Kikuchi A Complex formation of adenomatous polyposis coli gene product and Axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin | 21 | 8
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255 | 21 | 385 2001 CANCER RESEARCH 61(22):8247-8255
Wu R; Zhai Y; Fearon ER; Cho KR Diverse mechanisms of beta-catenin deregulation in ovarian endometrioid adenocarcinomas | 21 | 14
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256 | 3 | 421 2001 GENE 277(1-2):63-81
Reeves R Molecular biology of HMGA proteins: hubs of nuclear function | 21 | 0
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257 | 1 | 1 1998 AMERICAN JOURNAL OF HUMAN GENETICS 63(6):1588-1593
Semb H; Christofori G The tumor-suppressor function of E-cadherin | 20 | 3
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258 | 4 | 11 1999 AMERICAN JOURNAL OF PATHOLOGY 155(3):703-710
Van Nhieu JT; Renard CA; Wei Y; Cherqui D; Zafrani ES; Buendia MA Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation | 20 | 0
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259 | 1 | 77 1999 GENOMICS 57(2):235-248
Wang YK; Sporle R; Paperna T; Schughart K; Francke U Characterization and expression pattern of the frizzled gene Fzd9, the mouse homolog of FZD9 which is deleted in Williams-Beuren syndrome | 20 | 2
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260 | 11 | 324 2000 PROSTATE 45(4):323-334
Chesire DR; Ewing CM; Sauvageot J; Bova GS; Isaacs WB Detection and analysis of beta-catenin mutations in prostate cancer | 20 | 8
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261 | 3 | 413 2001 EUROPEAN JOURNAL OF IMMUNOLOGY 31(1):285-293
Staal FJT; Meeldijk J; Moerer P; Jay P; van de Weerdt BCM; Vainio S; Nolan GP; Clevers H Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription | 20 | 2
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262 | 17 | 470 2001 JOURNAL OF CELL BIOLOGY 154(2):369-387
Palmer HG; Gonzalez-Sancho JM; Espada J; Berciano MT; Puig I; Baulida J; Quintanilla M; Cano A; de Herreros AG; Lafarga M; Munoz A Vitamin D-3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling | 20 | 9
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263 | 3 | 523 2001 ONCOGENE 20(5):626-633
Zwerner JP; May WA PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors | 20 | 0
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264 | 16 | 573 2002 BIOLOGICAL CHEMISTRY 383(2):255-261
Brantjes H; Barker N; van Es J; Clevers H TCF: Lady justice casting the final verdict on the outcome of Wnt signalling | 20 | 2
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265 | 17 | 655 2002 INTERNATIONAL JOURNAL OF ONCOLOGY 21(6):1269-1273
Katoh M WNT and FGF gene clusters (Review) | 20 | 0
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266 | 3 | 668 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(19):16464-16469
Hanai J; Dhanabal M; Karumanchi SA; Albanese C; Waterman M; Chan B; Ramchandran R; Pestell R; Sukhatme VP Endostatin causes G(1) arrest of endothelial cells through inhibition of cyclin D1 | 20 | 2
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267 | 2 | 18 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 263(2):384-388
Wright M; Aikawa M; Szeto W; Papkoff J Identification of a Wnt-responsive signal transduction pathway in primary endothelial cells | 19 | 8
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268 | 3 | 129 1999 ONCOGENE 18(50):7080-7090
Ito K; Okamoto I; Araki N; Kawano Y; Nakao M; Fujiyama S; Tomita K; Mimori T; Saya H Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts | 19 | 0
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269 | 2 | 155 2000 AMERICAN JOURNAL OF PATHOLOGY 156(6):1997-2005
Furuuchi K; Tada M; Yamada H; Kataoka A; Furuuchi N; Hamada J; Takahashi M; Todo S; Moriuchi T Somatic mutations of the APC gene in primary breast cancers | 19 | 8
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270 | 4 | 183 2000 CANCER RESEARCH 60(16):4602-4609
Bissonnette M; Khare S; von Lintig FC; Wali RK; Nguyen L; Zhang YC; Hart J; Skarosi S; Varki N; Boss GR; Brasitus TA Mutational and nonmutational activation of p21(ras) in rat colonic azoxymethane-induced tumors: Effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1 | 19 | 1
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271 | 2 | 223 2000 EUROPEAN JOURNAL OF CANCER 36(2):242-248
Jonsson M; Borg A; Nilbert M; Andersson T Involvement of adenomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer | 19 | 6
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272 | 1 | 255 2000 INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 81(2):117-143
Wright NA Epithelial stem cell repertoire in the gut: clues to the origin of cell lineages, proliferative units and cancer | 19 | 1
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273 | 5 | 313 2000 ONCOGENE 19(34):3894-3901
Erdmann KS; Kuhlmann J; Lessmann V; Herrmann L; Eulenburg V; Muller O; Heumann R The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain | 19 | 5
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274 | 9 | 360 2001 CANCER RESEARCH 61(1):278-284
van de Wetering M; Barker N; Harkes IC; van der Heyden M; Dijk NJ; Hollestelle A; Klijn JGM; Clevers H; Schutte M Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling | 19 | 0
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275 | 9 | 394 2001 CLINICAL CANCER RESEARCH 7(4):901-908
Takayasu H; Horie H; Hiyama E; Matsunaga T; Hayashi Y; Watanabe Y; Suita S; Kaneko M; Sasaki F; Hashizume K; Ozaki T; Furuuchi K; Tada M; Ohnuma N; Nakagawara A Frequent deletions and mutations of the beta-catenin gene are associated with overexpression of cyclin D1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma | 19 | 9
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276 | 21 | 632 2002 GENES CHROMOSOMES & CANCER 34(3):255-268
Hajra KM; Fearon ER Cadherin and catenin alterations in human cancer | 19 | 4
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277 | 1 | 140 1999 SCIENCE 286(5444):1491-1492
Velculescu VE Essay: Amersham Pharmacia Biotech & Science Prize - Tantalizing transcriptomes - SAGE and its use in global gene expression analysis | 18 | 1
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278 | 3 | 239 2000 GENOME RESEARCH 10(12):2006-2021
Chrast R; Scott HS; Papasavvas MP; Rossier C; Antonarakis ES; Barras C; Davisson MT; Schmidt C; Estivill X; Dierssen M; Pritchard M; Antonarakis SE The mouse brain transcriptome by SAGE: Differences in gene expression between P30 brains of the partial trisomy 16 mouse model of Down syndrome (Ts65Dn) and normals | 18 | 0
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279 | 2 | 269 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(33):25805-25813
van de Water B; Tijdens IB; Verbrugge A; Huigsloot M; Dihal AA; Stevens JL; Jaken S; Mulder GJ Cleavage of the actin-capping protein alpha-adducin at Asp-Asp-Ser-Asp(633)-Ala by caspase-3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells | 18 | 0
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280 | 1 | 292 2000 MOLECULAR AND CELLULAR BIOLOGY 20(5):1733-1746
Kobayashi A; Yamagiwa H; Hoshino H; Muto A; Sato K; Morita M; Hayashi N; Yamamoto M; Igarashi K A combinatorial code for gene expression generated by transcription factor Bach2 and MAZR (MAZ-related factor) through the BTB/POZ domain | 18 | 0
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281 | 4 | 364 2001 CANCER RESEARCH 61(4):1671-1677
Bonvini P; An WG; Rosolen A; Nguyen P; Trepel J; de Herreros AG; Dunach M; Neckers LM Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription | 18 | 4
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282 | 9 | 367 2001 CANCER RESEARCH 61(6):2751-2758
Naishiro Y; Yamada T; Takaoka AS; Hayashi R; Hasegawa F; Imai K; Hirohashi S Restoration of epithelial cell polarity in a colorectal cancer cell line by suppression of beta-catenin/T-cell factor 4-mediated gene transactivation | 18 | 10
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283 | 2 | 374 2001 CANCER RESEARCH 61(12):4910-4915
Arango D; Corner GA; Wadler S; Catalano PJ; Augenlicht LH c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo | 18 | 2
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284 | 3 | 411 2001 EUROPEAN JOURNAL OF CANCER 37(1):12-22
Sharma RA; Manson MM; Gescher A; Steward WP Colorectal cancer chemoprevention: biochemical targets and clinical development of promising agents | 18 | 0
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285 | 6 | 431 2001 INTERNATIONAL JOURNAL OF CANCER 93(3):445-449
Koch A; Waha A; Tonn JC; Sorensen N; Berthold F; Wolter M; Reifenberger J; Hartmann W; Friedl W; Reifenberger G; Wiestler OD; Pietsch T Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors | 18 | 4
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286 | 3 | 433 2001 INTERNATIONAL JOURNAL OF CANCER 95(2):108-113
Woo DK; Kim HS; Lee HS; Kang YH; Yang HK; Kim WH Altered expression and mutation of beta-catenin gene in gastric carcinomas and cell lines | 18 | 4
|
287 | 5 | 459 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(48):45113-45119
Rockman SP; Currie SA; Ciavarella M; Vincan E; Dow C; Thomas RJS; Phillips WA Id2 is a target of the beta-catenin/T cell factor pathway in colon carcinoma | 18 | 9
|
288 | 7 | 60 1999 CYTOKINE & GROWTH FACTOR REVIEWS 10(3-4):255-265
Kikuchi A Modulation of Wnt signaling by Axin and Axil | 17 | 6
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289 | 1 | 103 1999 LABORATORY INVESTIGATION 79(12):1489-1499
Perry I; Tselepis C; Hoyland J; Iqbal TH; Sanders DSA; Cooper BT; Jankowski JAZ Reduced cadherin/catenin complex expression in celiac disease can be reproduced in vitro by cytokine stimulation | 17 | 2
|
290 | 1 | 176 2000 CANCER RESEARCH 60(4):1070-1076
Hassan AB; Howell JA Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice | 17 | 2
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291 | 8 | 187 2000 CANCER RESEARCH 60(22):6488-6495
Foster KW; Frost AR; McKie-Bell P; Lin CY; Engler JA; Grizzle WE; Ruppert JM Increase of GKLF messenger RNA and protein expression during progression of breast cancer | 17 | 0
|
292 | 4 | 228 2000 FEBS LETTERS 476(3):203-207
Dang DT; Bachman KE; Mahatan CS; Dang LH; Giardiello FM; Yang VW Decreased expression of the gut-enriched Kruppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients | 17 | 1
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293 | 1 | 234 2000 GENES & DEVELOPMENT 14(8):889-894
Robinson GW; Hennighausen L; Johnson PF Side-branching in the mammary gland: the progesterone-Wnt connection | 17 | 2
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294 | 2 | 289 2000 JOURNAL OF PATHOLOGY 190(4):412-416
Arends JW Molecular interactions in the Vogelstein model of colorectal carcinoma | 17 | 0
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295 | 3 | 291 2000 MODERN PATHOLOGY 13(10):1066-1071
Schlosshauer PW; Pirog EC; Levine RL; Ellenson LH Mutational analysis of the CTNNB1 and APC genes in uterine endometrioid carcinoma | 17 | 6
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296 | 11 | 312 2000 ONCOGENE 19(16):1992-2001
Sadot E; Simcha I; Iwai K; Ciechanover A; Geiger B; Ben-Ze'ev A Differential interaction of plakoglobin and beta-catenin with the ubiquitin-proteasome system | 17 | 10
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297 | 10 | 369 2001 CANCER RESEARCH 61(8):3245-3249
Cadoret A; Ovejero C; Saadi-Kheddouci S; Souil E; Fabre M; Romagnolo B; Kahn A; Perret C Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin | 17 | 10
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298 | 6 | 384 2001 CANCER RESEARCH 61(22):8089-8093
Hlubek F; Jung A; Kotzor N; Kirchner T; Brabletz T Expression of the invasion factor laminin gamma 2 in colorectal carcinomas is regulated by beta-catenin | 17 | 6
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299 | 5 | 395 2001 CLINICAL CANCER RESEARCH 7(8):2425-2433
Grotzer MA; Hogarty MD; Janss AJ; Liu XY; Zhao HQ; Eggert A; Sutton LN; Rorke LB; Brodeur GM; Phillips PC MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma | 17 | 1
|
300 | 1 | 17 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 256(3):584-590
Omer CA; Miller PJ; Diehl RE; Kral AM Identification of Tcf4 residues involved in high-affinity beta-catenin binding | 16 | 5
|
# | Cited nodes | Nodes / Authors | GCS | LCS |
301 | 1 | 70 1999 EUROPEAN JOURNAL OF CANCER PREVENTION 8():S39-S47
Laurent-Puig P; Blons H; Cugnenc PH Sequence of molecular genetic events in colorectal tumorigenesis | 16 | 0
|
302 | 1 | 152 2000 ALIMENTARY PHARMACOLOGY & THERAPEUTICS 14(10):1231-1247
Smith AM; Watson SA Review article: gastrin and colorectal cancer | 16 | 0
|
303 | 5 | 163 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 272(1):144-150
Neo SY; Zhang Y; Yaw LP; Li P; Lin SC Axin-induced apoptosis depends on the extent of its JNK activation and its ability to down-regulate beta-catenin levels | 16 | 7
|
304 | 4 | 201 2000 CELLULAR AND MOLECULAR LIFE SCIENCES 57(8-9):1207-1219
Desterro JMP; Rodriguez MS; Hay RT Regulation of transcription factors by protein degradation | 16 | 0
|
305 | 10 | 338 2001 AMERICAN JOURNAL OF PATHOLOGY 159(5):1613-1617
Jung A; Schrauder M; Oswald U; Knoll C; Sellberg P; Palmqvist R; Niedobitek G; Brabletz T; Kirchner T The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D-1, and p16(INK4A) and is a region of low proliferation | 16 | 4
|
306 | 4 | 387 2001 CARCINOGENESIS 22(2):315-320
Blum CA; Xu MR; Orner GA; Fong AT; Bailey GS; Stoner GD; Horio DT; Dashwood RH beta-catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol | 16 | 4
|
307 | 5 | 430 2001 INTERNATIONAL JOURNAL OF CANCER 92(6):839-842
Omholt K; Platz A; Ringborg U; Hansson J Cytoplasmic and nuclear accumulation of beta-catenin is rarely caused by CTNNB1 exon 3 mutations in cutaneous malignant melanoma | 16 | 12
|
308 | 16 | 472 2001 JOURNAL OF CELL BIOLOGY 155(6):1055-1064
Hsu W; Shakya R; Costantini F Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice | 16 | 7
|
309 | 7 | 528 2001 ONCOGENE 20(35):4884-4890
Dang DT; Mahatan CS; Dang LH; Agboola IA; Yang VW Expression of the gut-enriched Kruppel-like factor (Kruppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2 | 16 | 0
|
310 | 12 | 27 1999 CANCER AND METASTASIS REVIEWS 18(2):231-246
Waltzer L; Bienz M The control of beta-catenin and TCF during embryonic development and cancer | 15 | 4
|
311 | 1 | 44 1999 CELL GROWTH & DIFFERENTIATION 10(6):423-434
Foster KW; Ren SR; Louro ID; Lobo-Ruppert SM; McKie-Bell P; Grizzle W; Hayes MR; Broker TR; Chow LT; Ruppert JM Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: Transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF | 15 | 2
|
312 | 2 | 193 2000 CARCINOGENESIS 21(11):1935-1940
Iwamoto M; Ahnen DJ; Franklin WA; Maltzman TH Expression of beta-catenin and full-length APC protein in normal and neoplastic colonic tissues | 15 | 9
|
313 | 4 | 207 2000 CRITICAL REVIEWS IN ONCOGENESIS 11(1):19-62
Feo F; Pascale RM; Simile MM; De Miglio MR; Muroni MR; Calvisi D Genetic alterations in liver carcinogenesis: Implications for new preventive and therapeutic strategies | 15 | 2
|
314 | 2 | 361 2001 CANCER RESEARCH 61(2):565-569
Yang WC; Mathew J; Velcich A; Edelmann W; Kucherlapati R; Lipkin M; Yang K; Augenlicht LH Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a western-style high-risk diet by altering cell maturation in the intestinal mucosa | 15 | 4
|
315 | 11 | 378 2001 CANCER RESEARCH 61(17):6563-6568
Roh H; Green DW; Boswell CB; Pippin JA; Drebin JA Suppression of beta-catenin inhibits the neoplastic growth of APC-mutant colon cancer cells | 15 | 8
|
316 | 4 | 386 2001 CANCER RESEARCH 61(24):8664-8667
Zhang T; Otevrel T; Gao ZQ; Gao ZP; Ehrlich SM; Fields JZ; Boman BM Evidence that APC regulates survivin expression: A possible mechanism contributing to the stem cell origin of colon cancer | 15 | 7
|
317 | 9 | 452 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(28):25883-25888
Eleftheriou A; Yoshida M; Henderson BR Nuclear export of human beta-catenin can occur independent of CRM1 and the adenomatous polyposis coli tumor suppressor | 15 | 4
|
318 | 14 | 456 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(35):33147-33155
Kishida M; Hino S; Michiue T; Yamamoto H; Kishida S; Fukui A; Asashima M; Kikuchi A Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase I epsilon | 15 | 2
|
319 | 7 | 484 2001 JOURNAL OF PATHOLOGY 193(4):483-490
Park WS; Oh RR; Park JY; Kim PJ; Shin MS; Lee JH; Kim HS; Lee SH; Kim SY; Park YG; An WG; Kim HS; Jang JJ; Yoo NJ; Lee JY Nuclear localization of beta-catenin is an important prognostic factor in hepatoblastoma | 15 | 5
|
320 | 2 | 749 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(6):3830-3835
Berg T; Cohen SB; Desharnais J; Sonderegger C; Maslyar DJ; Goldberg J; Boger DL; Vogt PK Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts | 15 | 0
|
321 | 1 | 39 1999 CARCINOGENESIS 20(9):1709-1713
Erdman SH; Ignatenko NA; Powell MB; Blohm-Mangone KA; Holubec H; Guillen-Rodriguez JM; Gerner EW APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse | 14 | 4
|
322 | 2 | 75 1999 GENES TO CELLS 4(8):465-474
Hamada F; Murata Y; Nishida A; Fujita F; Tomoyasu Y; Nakamura M; Toyoshima K; Tabata T; Ueno N; Akiyama T Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC | 14 | 5
|
323 | 4 | 178 2000 CANCER RESEARCH 60(11):2864-2868
Anna CH; Sills RC; Foley JF; Stockton PS; Ton TV; Devereux TR beta-Catenin mutations and protein accumulation in all hepatoblastomas examined from B6C3F1 mice treated with anthraquinone or oxazepam | 14 | 2
|
324 | 5 | 185 2000 CANCER RESEARCH 60(22):6288-6292
Maiti S; Alam R; Amos CI; Huff V Frequent association of beta-catenin and WT1 mutations in Wilms tumors | 14 | 7
|
325 | 2 | 188 2000 CANCER RESEARCH 60(23):6611-6616
Tsujiuchi T; Tsutsumi M; Sasaki Y; Murata N; Konishi Y Mutations of adenomatous polyposis coli and beta-catenin genes during progression of lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats | 14 | 5
|
326 | 3 | 248 2000 IMMUNOLOGICAL REVIEWS 175():94-103
O'Riordan M; Grosschedl R Transcriptional regulation of early B-lymphocyte differentiation | 14 | 0
|
327 | 11 | 279 2000 JOURNAL OF CELL SCIENCE 113(6):911-919
Behrens J Cross-regulation of the Wnt signalling pathway: a role of MAP kinases | 14 | 3
|
328 | 6 | 377 2001 CANCER RESEARCH 61(17):6345-6349
Lin YM; Ono K; Satoh S; Ishiguro H; Fujita M; Miwa N; Tanaka T; Tsunoda T; Yang KC; Nakamura Y; Furukawa Y Identification of AF17 as a downstream gene of the beta-catenin/T-cell factor pathway and its involvement in colorectal carcinogenesis | 14 | 8
|
329 | 8 | 381 2001 CANCER RESEARCH 61(21):7722-7726
Fujita M; Furukawa Y; Tsunoda T; Tanaka T; Ogawa M; Nakamura Y Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas | 14 | 9
|
330 | 3 | 439 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 18(6):1271-1278
Kondoh N; Wakatsuki T; Hada A; Shuda M; Tanaka K; Arai M; Yamamoto M Genetic and epigenetic events in human hepatocarcinogenesis (Review) | 14 | 0
|
331 | 10 | 499 2001 MOLECULAR AND CELLULAR BIOLOGY 21(1):330-342
Hino SI; Kishida S; Michiue T; Fukui A; Sakamoto I; Takada S; Asashima M; Kikuchi A Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein | 14 | 3
|
332 | 8 | 502 2001 MOLECULAR AND CELLULAR BIOLOGY 21(3):902-915
Goruppi S; Chiaruttini C; Ruaro ME; Varnum B; Schneider C Gas6 induces growth, beta-catenin stabilization, and T-cell factor transcriptional activation in contact-inhibited C57 mammary cells | 14 | 3
|
333 | 2 | 525 2001 ONCOGENE 20(22):2727-2736
Baba M; Hirai S; Kawakami S; Kishida T; Sakai N; Kaneko S; Yao M; Shuin T; Kubota Y; Hosaka M; Ohno S Tumor suppressor protein VHL is induced at high cell density and mediates contact inhibition of cell growth | 14 | 0
|
334 | 6 | 532 2001 ONCOGENE 20(41):5810-5817
Ugolini F; Charafe-Jauffret E; Bardou VJ; Geneix J; Adelaide J; Labat-Moleur F; Penault-Llorca F; Longy M; Jacquemier J; Birnbaum D; Pebusque MJ WNT pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type | 14 | 4
|
335 | 5 | 572 2002 BIOESSAYS 24(1):54-64
Johnston LA; Gallant P Control of growth and organ size in Drosophila | 14 | 0
|
336 | 20 | 611 2002 EMBO JOURNAL 21(10):2303-2311
Hurlstone A; Clevers H T-cell factors: turn-ons and turn-offs | 14 | 3
|
337 | 7 | 672 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(23):20702-20710
Pawlowski JE; Ertel JR; Allen MP; Xu M; Butler C; Wilson EM; Wierman ME Liganded androgen receptor interaction with beta-catenin - Nuclear co-localization and modulation of transcriptional activity in neuronal cells | 14 | 3
|
338 | 1 | 696 2002 JOURNAL OF IMMUNOLOGY 168(10):4837-4845
Denys A; Udalova IA; Smith C; Williams LM; Ciesielski CJ; Campbell J; Andrews C; Kwaitkowski D; Foxwell BMJ Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages | 14 | 0
|
339 | 10 | 705 2002 JOURNAL OF PATHOLOGY 197(4):492-509
Brittan M; Wright NA Gastrointestinal stem cells | 14 | 0
|
340 | 12 | 713 2002 LUNG CANCER 36(2):115-124
Bremnes RM; Veve R; Hirsch FR; Franklin WA The E-cadherin cell-cell adhesion complex and lung cancer invasion, metastasis, and prognosis | 14 | 3
|
341 | 5 | 97 1999 JOURNAL OF CELL BIOLOGY 147(2):367-374
Nelson RW; Gumbiner BM A cell-free assay system for beta-catenin signaling that recapitulates direct inductive events in the early Xenopus laevis embryo | 13 | 3
|
342 | 5 | 169 2000 BIOLOGICAL SIGNALS AND RECEPTORS 9(2):115-121
Peluso JJ N-cadherin-mediated cell contact regulates ovarian surface epithelial cell survival | 13 | 1
|
343 | 3 | 229 2000 FRONTIERS IN BIOSCIENCE 5():D372-D390
Amanatullah DF; Reutens AT; Zafonte BT; Fu MF; Mani S; Pestell RG Cell-cycle dysregulation and the molecular mechanisms of prostate cancer | 13 | 0
|
344 | 7 | 297 2000 MOLECULAR MEDICINE TODAY 6(12):462-469
Sieber OM; Tomlinson IP; Lamlum H The adenomatous polyposis coli (APC) tumour suppressor - genetics, function and disease | 13 | 3
|
345 | 18 | 314 2000 ONCOGENE 19(50):5720-5728
Williams BO; Barish GD; Klymkowsky MW; Varmus HE A comparative evaluation of beta-catenin and plakoglobin signaling activity | 13 | 6
|
346 | 4 | 368 2001 CANCER RESEARCH 61(7):2899-2906
Sellin JH; Umar S; Xiao JG; Morris AP Increased beta-catenin expression and nuclear translocation accompany cellular hyperproliferation in vivo | 13 | 4
|
347 | 7 | 373 2001 CANCER RESEARCH 61(11):4445-4449
Chen RH; McCormick F Selective targeting to the hyperactive beta-catenin/T-cell factor pathway in colon cancer cells | 13 | 4
|
348 | 5 | 375 2001 CANCER RESEARCH 61(16):6050-6054
Zhang XB; Gaspard JP; Chung DC Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia | 13 | 6
|
349 | 14 | 393 2001 CHEMICAL REVIEWS 101(8):2527-2540
Ali A; Hoeflich KP; Woodgett JR Glycogen synthase kinase-3: Properties, functions, and regulation | 13 | 0
|
350 | 10 | 500 2001 MOLECULAR AND CELLULAR BIOLOGY 21(2):562-574
Ziemer LT; Pennica D; Levine AJ Identification of a mouse homolog of the human BTEB2 transcription factor as a beta-catenin-independent Wnt-1-responsive gene | 13 | 5
|
351 | 7 | 507 2001 MOLECULAR AND CELLULAR BIOLOGY 21(23):8143-8156
Zhang F; White RL; Neufeld KL Cell density and phosphorylation control the subcellular localization of adenomatous polyposis coli protein | 13 | 5
|
352 | 6 | 533 2001 ONCOGENE 20(42):5972-5981
Saadi-Kheddouci S; Berrebi D; Romagnolo B; Cluzeaud F; Peuchmaur M; Kahn A; Vandewalle A; Perret C Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene | 13 | 0
|
353 | 4 | 548 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(26):14973-14978
Yan D; Wiesmann M; Rohan M; Chan V; Jefferson AB; Guo LD; Sakamoto D; Caothien RH; Fuller JH; Reinhard C; Garcia PD; Randazzo FM; Escobedo J; Fantl WJ; Williams LT Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta-catenin signaling is activated in human colon tumors | 13 | 7
|
354 | 2 | 157 2000 AMERICAN JOURNAL OF PATHOLOGY 157(5):1563-1573
Wielenga VJM; van der Voort R; Taher TEI; Smit L; Beuling EA; van Krimpen C; Spaargaren M; Pals ST Expression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancer | 12 | 1
|
355 | 1 | 173 2000 CANCER GENETICS AND CYTOGENETICS 121(1):17-21
Masramon L; Ribas M; Cifuentes P; Arribas R; Garcia F; Egozcue J; Peinado MA; Miro R Cytogenetic characterization of two colon cell lines by using conventional G-banding, comparative genomic hybridization, and whole chromosome painting | 12 | 0
|
356 | 3 | 249 2000 IMMUNOLOGICAL REVIEWS 176():47-68
Gold MR; Ingham RJ; McLeod SJ; Christian SL; Scheid MP; Duronio V; Santos L; Matsuuchi L Targets of B-cell antigen receptor signaling: the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase-3 signaling pathway and the Rap 1 GTPase | 12 | 0
|
357 | 6 | 264 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(27):20707-20716
Stewart DB; Barth AIM; Nelson WJ Differential regulation of endogenous cadherin expression in Madin-Darby canine kidney cells by cell-cell adhesion and activation of beta-catenin signaling | 12 | 1
|
358 | 1 | 287 2000 JOURNAL OF MOLECULAR BIOLOGY 301(1):147-156
Day CL; Alber T Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor | 12 | 1
|
359 | 5 | 486 2001 JOURNAL OF PATHOLOGY 194(1):59-67
Saegusa M; Okayasu I Frequent nuclear beta-catenin accumulation and associated mutations in endometrioid-type endometrial and ovarian carcinomas with squamous differentiation | 12 | 7
|
360 | 10 | 682 2002 JOURNAL OF CELL BIOLOGY 158(3):529-539
Hanai J; Gloy J; Karumanchi SA; Kale S; Tang JA; Hu GA; Chan B; Ramchandran R; Jha V; Sukhatme VP; Sokol S Endostatin is a potential inhibitor of Wnt signaling | 12 | 1
|
361 | 1 | 54 1999 CURRENT BIOLOGY 9(2):R62-R65
Fearon ER; Dang CV Cancer genetics: Tumor suppressor meets oncogene | 11 | 0
|
362 | 1 | 63 1999 DEVELOPMENTAL BIOLOGY 207(2):350-363
Paulson AF; Fang X; Ji H; Reynolds AB; McCrea PD Misexpression of the catenin p120(ctn)1A perturbs Xenopus gastrulation but does not elicit Wnt-directed axis specification | 11 | 0
|
363 | 1 | 91 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(32):22705-22712
Spychala J; Zimmermann AG; Mitchell BS Tissue-specific regulation of the ecto-5 '-nucleotidase promoter - Role of the cAMP response element site in mediating repression by the upstream regulatory region | 11 | 0
|
364 | 1 | 245 2000 HISTOLOGY AND HISTOPATHOLOGY 15(1):251-260
Tucker EL; Pignatelli M Catenins and their associated proteins in colorectal cancer | 11 | 2
|
365 | 3 | 268 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(32):25008-25014
Zhang Y; Neo SY; Han JH; Lin SC Dimerization choices control the ability of axin and dishevelled to activate c-jun N-terminal kinase/stress-activated protein kinase | 11 | 3
|
366 | 1 | 329 2000 SURGERY 127(5):552-561
Shiozaki H; Doki Y; Kawanishi K; Shamma A; Yano M; Inoue M; Monden M Clinical application of malignancy potential grading as a prognostic factor of human esophageal cancers | 11 | 0
|
367 | 1 | 343 2001 APOPTOSIS 6(1-2):133-137
Henriksson M; Selivanova G; Lindstrom M; Wiman KG Inactivation of Myc-induced p53-dependent apoptosis in human tumors | 11 | 0
|
368 | 4 | 379 2001 CANCER RESEARCH 61(18):6656-6659
Fujimori M; Ikeda S; Shimizu Y; Okajima M; Asahara T Accumulation of beta-catenin protein and mutations in exon 3 of beta-catenin gene in gastrointestinal carcinoid tumor | 11 | 5
|
369 | 5 | 400 2001 CURRENT OPINION IN ONCOLOGY 13(1):78-83
Park BH; Breyer B; He TC Peroxisome proliferator-activated receptors: roles in tumorigenesis and chemoprevention in human cancer | 11 | 0
|
370 | 15 | 404 2001 EMBO JOURNAL 20(16):4500-4511
Sampson EM; Haque ZK; Ku MC; Tevosian SG; Albanese C; Pestell RG; Paulson KE; Yee AS Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1 | 11 | 3
|
371 | 3 | 481 2001 JOURNAL OF INVESTIGATIVE DERMATOLOGY 116(5):739-742
Bonifas JM; Pennypacker S; Chuang PT; McMahon AP; Williams M; Rosenthal A; de Sauvage FJ; Epstein EH Activation of expression of hedgehog target genes in basal cell carcinomas | 11 | 1
|
372 | 22 | 482 2001 JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA 6(1):37-52
Smalley MJ; Dale TC Wnt signaling and mammary tumorigenesis | 11 | 2
|
373 | 13 | 504 2001 MOLECULAR AND CELLULAR BIOLOGY 21(17):5857-5868
Danilkovitch-Miagkova A; Miagkov A; Skeel A; Nakaigawa N; Zbar B; Leonard EJ Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway | 11 | 0
|
374 | 5 | 505 2001 MOLECULAR AND CELLULAR BIOLOGY 21(19):6626-6639
Miller LD; Park KS; Guo QBM; Alkharouf NW; Malek RL; Lee NH; Liu ET; Cheng SY Silencing of Wnt signaling and activation of multiple metabolic pathways in response to thyroid hormone-stimulated cell proliferation | 11 | 0
|
375 | 15 | 553 2002 ADVANCES IN CANCER RESEARCH, VOL 84 84():203-229
Manoukian AS; Woodgett JR Role of glycogen synthase kinase-3 in cancer: Regulation by Wnts and other signaling pathways | 11 | 0
|
376 | 18 | 584 2002 CANCER CELL 1(2):145-155
Kolligs FT; Nieman MT; Winer I; Hu G; Van Mater D; Feng Y; Smith IM; Wu R; Zhai YL; Cho KR; Fearon ER ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation | 11 | 8
|
377 | 21 | 630 2002 GENES & DEVELOPMENT 16(16):2058-2072
Conacci-Sorrell ME; Ben-Yedidia T; Shtutman M; Feinstein E; Einat P; Ben-Ze'ev A Nr-CAM is a target gene of the beta-catenin/LEF-1 in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis | 11 | 0
|
378 | 14 | 751 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(12):8265-8270
Chan TA; Wang ZH; Dang LH; Vogelstein B; Kinzler KW Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation | 11 | 5
|
379 | 2 | 753 2002 RECENT PROGRESS IN HORMONE RESEARCH, VOL 57 57():195-220
Richards JS; Russell DL; Ochsner S; Hsieh M; Doyle KH; Falender AE; Lo YK; Sharma SC Novel signaling pathways that control ovarian follicular development, ovulation, and luteinization | 11 | 0
|
380 | 1 | 12 1999 AMERICAN JOURNAL OF PATHOLOGY 155(4):1027-1032
Sarbia M; Loberg C; Wolter M; Arjumand J; Heep H; Reifenberger G; Gabbert HE Expression of Bcl-2 and amplification of c-myc are frequent in basaloid squamous cell carcinomas of the esophagus | 10 | 2
|
381 | 1 | 94 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(43):31062-31067
Alberta JA; Auger KR; Batt D; Iannarelli P; Hwang G; Elliott HL; Duke R; Roberts TM; Stiles CD Platelet-derived growth factor stimulation of monocyte chemoattractant protein-1 gene expression is mediated by transient activation of the phosphoinositide 3-kinase signal transduction pathway | 10 | 0
|
382 | 3 | 159 2000 ANTICANCER RESEARCH 20(5A):2835-2847
Papadopoulos V; Kapsis A; Li H; Amri H; Hardwick M; Culty M; Kasprzyk PG; Carlson M; Moreau JP; Drieu K Drug-induced inhibition of the peripheral-type benzodiazepine receptor expression and cell proliferation in human breast cancer cells | 10 | 0
|
383 | 3 | 165 2000 BIOCHEMISTRY-MOSCOW 65(1):2-27
Kopnin BP Targets of oncogenes and tumor suppressors: Key for understanding basic mechanisms of carcinogenesis | 10 | 0
|
384 | 6 | 243 2000 GYNECOLOGIC ONCOLOGY 77(1):97-104
Furlong MT; Morin PJ Rare activation of the TCF/beta-catenin pathway in ovarian cancer | 10 | 3
|
385 | 6 | 305 2000 NEUROSURGERY 47(4):888-901
Taylor MD; Mainprize TG; Rutka JT Molecular insight into medulloblastoma and central nervous system primitive neuroectodermal tumor biology from hereditary syndromes: A review | 10 | 1
|
386 | 4 | 315 2000 ONCOGENE 19(50):5755-5763
Kuraguchi M; Edelmann W; Yang K; Lipkin M; Kucherlapati R; Brown AMC Tumor-associated Apc mutations in Mlh1(-/-) Apc(1638N) mice reveal a mutational signature of Mlh1 deficiency | 10 | 0
|
387 | 4 | 325 2000 REVIEWS OF REPRODUCTION 5(1):53-61
Rowlands TM; Symonds JM; Farookhi R; Blaschuk OW Cadherins: crucial regulators of structure and function in reproductive tissues | 10 | 0
|
388 | 1 | 408 2001 EMBO REPORTS 2(4):306-312
Vietor I; Bader T; Paiha K; Huber LA Perturbation of the tight junction permeability barrier by occludin loop peptides activates beta-catenin/TCF/LEF-mediated transcription | 10 | 3
|
389 | 10 | 424 2001 HEPATOLOGY 33(5):1098-1109
Monga SPS; Pediaditakis P; Mule K; Stolz DB; Michalopoulos GK Changes in wnt/beta-catenin pathway during regulated growth in rat liver regeneration | 10 | 2
|
390 | 11 | 449 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(21):18193-18199
Jaiswal AS; Narayan S p53-dependent transcriptional regulation of the APC promoter in colon cancer cells treated with DNA alkylating agents | 10 | 1
|
391 | 16 | 454 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(29):26875-26882
Yamamoto H; Hinoi T; Michiue T; Fukui A; Usui H; Janssens V; Van Hoof C; Goris J; Asashima M; Kikuchi A Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A | 10 | 2
|
392 | 6 | 457 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(45):42276-42286
Lamberti C; Lin KM; Yamamoto Y; Verma U; Verma IM; Byers S; Gaynor RB Regulation of beta-catenin function by the I kappa B kinases | 10 | 5
|
393 | 8 | 485 2001 JOURNAL OF PATHOLOGY 194(1):20-26
Clavel CE; Nollet F; Berx G; Tejpar S; Naworcki-Raby B; Kaplan HH; van Roy FM; Birembaut PL Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours | 10 | 1
|
394 | 11 | 524 2001 ONCOGENE 20(5):645-653
Dihlmann S; Siermann A; Doeberitz MV The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/TCF-4 signaling | 10 | 0
|
395 | 9 | 534 2001 ONCOGENE 20(43):6250-6257
Marotta A; Tan C; Gray V; Malik S; Gallinger S; Sanghera J; Dupuis B; Owen D; Dedhar S; Salh B Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis | 10 | 2
|
396 | 13 | 586 2002 CANCER CELL 1(4):369-379
Patturajan M; Nomoto S; Sommer M; Fomenkov A; Hibi K; Zangen R; Poliak N; Califano J; Trink B; Ratovitski E; Sidransky D Delta Np63 induces beta-catenin nuclear accumulation and signaling | 10 | 1
|
397 | 7 | 629 2002 GENE THERAPY 9(4):270-281
Fuerer C; Iggo R Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway | 10 | 1
|
398 | 12 | 662 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(3):1884-1891
Miravet S; Piedra J; Miro F; Itarte E; de Herreros AG; Dunach M The transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobin | 10 | 3
|
399 | 21 | 681 2002 JOURNAL OF CELL BIOLOGY 157(3):429-440
You ZB; Saims D; Chen SQ; Zhang ZC; Guttridge DC; Guan KL; MacDougald OA; Brown AMC; Evan G; Kitajewski J; Wang CY Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis | 10 | 1
|
400 | 17 | 728 2002 ONCOGENE 21(17):2679-2694
Chesire DR; Ewing CM; Gage WR; Isaacs WB In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis | 10 | 3
|
# | Cited nodes | Nodes / Authors | GCS | LCS |
401 | 13 | 734 2002 ONCOGENE 21(38):5861-5867
Takahashi M; Tsunoda T; Seiki M; Nakamura Y; Furukawa Y Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers | 10 | 1
|
402 | 8 | 761 2002 VIRCHOWS ARCHIV 440(4):381-386
Sekine S; Shibata T; Yamauchi Y; Nakanishi Y; Shimoda T; Sakamoto M; Hirohashi S beta-catenin mutations in sporadic fundic gland polyps | 10 | 4
|
403 | 1 | 15 1999 ANTICANCER MOLECULES: STRUCTURE, FUNCTION, AND DESIGN 886():37-47
Ben-Ze'Ev A The dual role of cytoskeletal anchor proteins in cell adhesion and signal transduction | 9 | 0
|
404 | 1 | 28 1999 CANCER PREVENTION: NOVEL NUTRIENT AND PHARMACEUTICAL DEVELOPMENTS 889():20-31
Augenlicht LH; Bordonaro M; Heerdt BG; Mariadason J; Velcich A Cellular mechanisms of risk and transformation | 9 | 2
|
405 | 3 | 160 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 268(1):20-24
Tsuji T; Miyazaki M; Sakaguchi M; Inoue Y; Namba M A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines | 9 | 0
|
406 | 4 | 167 2000 BIOESSAYS 22(10):902-910
Kitajewski J; Sassoon D The emergence of molecular gynecology: homeobox and Wnt genes in the female reproductive tract | 9 | 0
|
407 | 5 | 190 2000 CANCER RESEARCH 60(24):7057-7065
Sasaki CY; Lin HC; Morin PJ; Longo DL Truncation of the extracellular region abrogrates cell contact but retains the growth-suppressive activity of E-cadherin | 9 | 0
|
408 | 1 | 241 2000 GUT 47(6):812-819
Kishimoto Y; Takata N; Jinnai T; Morisawa T; Shiota G; Kawasaki H; Hasegawa J Sulindac and a cyclooxygenase-2 inhibitor, etodolac, increase APC mRNA in the colon of rats treated with azoxymethane | 9 | 5
|
409 | 5 | 336 2001 AMERICAN JOURNAL OF CLINICAL PATHOLOGY 115(6):835-840
Sarbia M; Arjumand J; Wolter M; Reifenberger G; Heep H; Gabbert HE Frequent c-myc amplification in high-grade dysplasia and adenocarcinoma in Barrett esophagus | 9 | 1
|
410 | 3 | 420 2001 GASTROENTEROLOGY 120(7):1680-1688
Bartkova J; Thullberg M; Slezak P; Jaramillo E; Rubio C; Thomassen LH; Bartek J Aberrant expression of G1-phase cell cycle regulators in flat and exophytic adenomas of the human colon | 9 | 0
|
411 | 10 | 453 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(28):26180-26188
Mao CD; Hoang P; DiCorleto PE Lithium inhibits cell cycle progression and induces stabilization of p53 in bovine aortic endothelial cells | 9 | 2
|
412 | 1 | 494 2001 MICROSCOPY RESEARCH AND TECHNIQUE 52(2):171-181
Strange R; Metcalfe T; Thackray L; Dang M Apoptosis in normal and neoplastic mammary gland development | 9 | 0
|
413 | 5 | 519 2001 NATURE STRUCTURAL BIOLOGY 8(12):1048-1052
Graham TA; Ferkey DM; Mao F; Kimelman D; Xu WQ Tcf4 can specifically recognize beta-catenin using alternative conformations | 9 | 2
|
414 | 5 | 557 2002 AMERICAN JOURNAL OF PATHOLOGY 160(4):1361-1369
Abraham SC; Klimstra DS; Wilentz RE; Yeo CJ; Conlon K; Brennan M; Cameron JL; Wu TT; Hruban RH Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor beta-catenin mutations | 9 | 3
|
415 | 11 | 561 2002 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 3():101-128
Grady WM; Markowitz SD Genetic and epigenetic alterations in colon cancer | 9 | 0
|
416 | 11 | 625 2002 GASTROENTEROLOGY 122(1):60-71
Ougolkov AV; Yamashita K; Mai M; Minamoto T Oncogenic beta-catenin and MMP-7 (matrilysin) cosegregate in late-stage clinical colon cancer | 9 | 7
|
417 | 5 | 634 2002 GUT 50(5):658-664
Shimada T; Kojima K; Yoshiura K; Hiraishi H; Terano A Characteristics of the peroxisome proliferator activated receptor gamma (PPAR gamma) ligand induced apoptosis in colon cancer cells | 9 | 0
|
418 | 8 | 665 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(9):7453-7465
Briggs MW; Li ZG; Sacks DB IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin | 9 | 0
|
419 | 9 | 666 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(16):14329-14335
Tice DA; Szeto W; Soloviev I; Rubinfeld B; Fong SE; Dugger DL; Winer J; Williams PM; Wieand D; Smith V; Schwall RH; Pennica D; Polakis P Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling | 9 | 1
|
420 | 6 | 702 2002 JOURNAL OF PATHOLOGY 196(2):145-153
Wong SCC; Lo SFE; Lee KC; Yam JWP; Chan JKC; Hsiao WLW Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours | 9 | 4
|
421 | 1 | 721 2002 MOLECULAR CELL 10(3):509-521
Herold S; Wanzel M; Beuger V; Frohme C; Beul D; Hillukkala T; Syvaoja J; Saluz HP; Haenel F; Eilers M Negative regulation of the mammalian UV response by Myc through association with Miz-1 | 9 | 2
|
422 | 3 | 51 1999 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 64():141-147
Korswagen HC; Clevers HC Activation and repression of Wingless/Wnt target genes by the TCF/LEF-1 family of transcription factors | 8 | 0
|
423 | 1 | 86 1999 JAPANESE JOURNAL OF CANCER RESEARCH 90(8):824-828
Yamada Y; Yoshimi N; Sugie S; Suzui M; Matsunaga K; Kawabata K; Hara A; Mori H beta-catenin (Ctnnb1) gene mutations in diethylnitrosamine (DEN)-induced liver tumors in male F344 rats | 8 | 1
|
424 | 1 | 123 1999 ONCOGENE 18(34):4777-4787
Yamashita A; Hakura A; Inoue H Suppression of anchorage-independent growth of human cancer cell lines by the drs gene | 8 | 1
|
425 | 2 | 126 1999 ONCOGENE 18(44):5959-5966
Gazit A; Yaniv A; Bafico A; Pramila T; Igarashi M; Kitajewski J; Aaronson SA Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response | 8 | 4
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426 | 4 | 197 2000 CELL ADHESION AND COMMUNICATION 7(5):391-408
Luber B; Candidus S; Handschuh G; Mentele E; Hutzler P; Feller S; Voss J; Hofler H; Becker KF Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate | 8 | 2
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427 | 4 | 251 2000 INTERNATIONAL JOURNAL OF CANCER 86(4):533-537
Wijnhoven BPL; Nollet F; De Both NJ; Tilanus HW; Dinjens WNM Genetic alterations involving exon 3 of the beta-catenin gene do not play a role in adenocarcinomas of the esophagus | 8 | 3
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428 | 1 | 334 2001 ADVANCES IN CANCER RESEARCH, VOL 80 80():83-114
Shibata D; Aaltonen LA Genetic predisposition and somatic diversification in tumor development and progression | 8 | 0
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429 | 1 | 340 2001 ANALYTICAL BIOCHEMISTRY 288(2):141-148
Kim S; Zeller K; Dang CV; Sandgren EP; Lee LA A strategy to identify differentially expressed genes using representational difference analysis and cDNA arrays | 8 | 0
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430 | 11 | 342 2001 ANTICANCER RESEARCH 21(2A):911-915
Dimberg J; Hugander A; Sirsjo A; Soderkvist P Enhanced expression of cyclooxygenase-2 and nuclear beta-catenin are related to mutations in the APC gene in human colorectal cancer | 8 | 0
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431 | 6 | 407 2001 EMBO JOURNAL 20(22):6203-6212
Spink KE; Fridman SG; Weis WI Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex | 8 | 0
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432 | 4 | 435 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 18(3):541-548
Yang SZ; Kohno N; Yokoyama A; Kondo K; Hamada H; Hiwada K Decreased E-cadherin augments beta-catenin nuclear localization: Studies in breast cancer cell lines | 8 | 1
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433 | 4 | 447 2001 JAPANESE JOURNAL OF CANCER RESEARCH 92(6):617-623
Yamada Y; Yoshimi N; Hirose Y; Hara A; Shimizu M; Kuno T; Katayama M; Qiao Z; Mori H Suppression of occurrence and advancement of beta-catenin-accumulated crypts, possible premalignant lesions of colon cancer, by selective cyclooxygenase-2 inhibitor, celecoxib | 8 | 1
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434 | 7 | 448 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(12):8968-8978
Pukrop T; Gradl D; Henningfeld KA; Knochel W; Wedlich D; Kuhl M Identification of two regulatory elements within the high mobility group box transcription factor XTCF-4 | 8 | 1
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435 | 12 | 455 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(34):32152-32159
Zhang Y; Qiu WJ; Liu DX; Neo SY; He X; Lin SC Differential molecular assemblies underlie the dual function of axin in modulating the Wnt and JNK pathways | 8 | 2
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436 | 1 | 498 2001 MOLECULAR AND CELLULAR BIOCHEMISTRY 227(1-2):153-165
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437 | 4 | 545 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(8):4646-4651
Kolli S; Buchmann AM; Williams J; Weitzman S; Thimmapaya B Antisense-mediated depletion of p300 in human cells leads to premature G(1) exit and up-regulation of c-MYC | 8 | 1
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438 | 6 | 554 2002 AMERICAN JOURNAL OF GASTROENTEROLOGY 97(3):542-553
Husain SS; Szabo IL; Tarnawski AS NSAID inhibition of GI cancer growth: Clinical implications and molecular mechanisms of action | 8 | 0
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439 | 11 | 595 2002 CANCER RESEARCH 62(12):3503-3506
Clements WM; Wang J; Sarnaik A; Kim OJ; MacDonald J; Fenoglio-Preiser C; Groden J; Lowy AM beta-catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer | 8 | 5
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440 | 1 | 601 2002 CELL DEATH AND DIFFERENTIATION 9(5):513-526
Yamakawa-Karakida N; Sugita K; Inukai T; Goi K; Nakamura M; Uno K; Sato H; Kagami K; Barker N; Nakazawa S Ligand activation of peroxisome proliferator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity | 8 | 0
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441 | 4 | 612 2002 EMBO REPORTS 3(6):521-526
Shaw PE Peptidyl-prolyl isomerases: a new twist to transcription | 8 | 2
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442 | 13 | 623 2002 EXPERIMENTAL CELL RESEARCH 280(1):119-133
Muller T; Bain G; Wang X; Papkoff J Regulation of epithelial cell migration and tumor formation by beta-catenin signaling | 8 | 3
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443 | 14 | 645 2002 INTERNATIONAL JOURNAL OF CANCER 100(5):549-556
Reifenberger J; Knobbe CB; Wolter M; Blaschke B; Schulte KW; Pietsch T; Ruzicka T; Reifenberger G Molecular genetic analysis of malignant melanomas for aberrations of the Wnt signaling pathway genes CTNNB1, APC, ICAT and BTRC | 8 | 4
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444 | 11 | 667 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(18):15843-15850
Wong MH; Huelsken J; Birchmeier W; Gordon JI Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling | 8 | 1
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445 | 7 | 683 2002 JOURNAL OF CELL BIOLOGY 158(6):1079-1087
Widlund HR; Horstmann MA; Price ER; Cui JI; Lessnick SL; Wu M; He X; Fisher DE beta-Catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor | 8 | 4
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446 | 36 | 762 2002 VIRCHOWS ARCHIV 441(1):1-11
Brabletz T; Jung A; Kirchner T beta-Catenin and the morphogenesis of colorectal cancer | 8 | 4
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447 | 1 | 16 1999 ANTICANCER RESEARCH 19(6A):4715-4728
Teh BT; Larsson C; Nordenskjold M Tumor suppressor genes (TSG) | 7 | 0
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448 | 3 | 19 1999 BIOCHEMICAL JOURNAL 344():565-570
Baulida J; Batlle E; de Herreros AG Adenomatous polyposis coil protein (APC)-independent regulation of beta-catenin/Tcf-4 mediated transcription in intestinal cells | 7 | 5
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449 | 1 | 23 1999 BRITISH JOURNAL OF CANCER 81(7):1116-1121
Park KS; Kim NG; Kim JJ; Kim H; Ahn YH; Choi KY Differential regulation of MAP kinase cascade in human colorectal tumorigenesis | 7 | 0
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450 | 1 | 66 1999 ENDOCRINE 10(1):67-76
Heinrich CA; Lail-Trecker MR; Peluso JJ; White BA Negative regulation of N-cadherin-mediated cell-cell adhesion by the estrogen receptor signaling pathway in rat pituitary GH(3) cells | 7 | 1
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451 | 1 | 101 1999 JOURNAL OF INVESTIGATIVE DERMATOLOGY 113(2):258-262
Takata M; Fujimoto A; Aoki H; Hatta N; Ooi A; Takehara K erbB-2 overexpression but no activation of beta-catenin gene in extramammary Paget's disease | 7 | 0
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452 | 1 | 150 1999 WORLD JOURNAL OF GASTROENTEROLOGY 5(5):451-454
Zhang J; Lai MD; Chen J Methylation status of p16 gene in colorectal carcinoma and normal colonic mucosa | 7 | 0
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453 | 4 | 164 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 276(3):1162-1169
Julius MA; Schelbert B; Hsu W; Fitzpatrick E; Jho E; Fagotto F; Costantini F; Kitajewski J Domains of Axin and disheveled required for interaction and function in Wnt signaling | 7 | 3
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454 | 1 | 194 2000 CARDIOVASCULAR RESEARCH 45(3):621-629
Rezvani M; Barrans JD; Dai KS; Liew CC Apoptosis-related genes expressed in cardiovascular development and disease: an EST approach | 7 | 0
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455 | 1 | 254 2000 INTERNATIONAL JOURNAL OF CANCER 90(4):175-185
Kennedy AS; Harrison GH; Mansfield CM; Zhou XJ; Xu JF; Balcer-Kubiczek EK Survival of colorectal cancer cell lines treated with paclitaxel, radiation, and 5-FU: Effect of TP53 or hMLH1 deficiency | 7 | 0
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456 | 3 | 256 2000 JAPANESE JOURNAL OF CANCER RESEARCH 91(6):597-603
Ishiguro H; Furukawa Y; Daigo Y; Miyoshi Y; Nagasawa Y; Nishiwaki T; Kawasoe T; Fujita M; Satoh S; Miwa N; Fujii Y; Nakamura Y Isolation and characterization of human NBL4, a gene involved in the beta-catenin/Tcf signaling pathway | 7 | 7
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457 | 1 | 263 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(24):18470-18475
Rezvani M; Liew CC Role of the adenomatous polyposis coli gene product in human cardiac development and disease | 7 | 0
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458 | 3 | 316 2000 ONCOLOGY 59(4):302-309
Maruyama K; Ochiai A; Akimoto S; Nakamura S; Baba S; Moriya Y; Hirohashi S Cytoplasmic beta-catenin accumulation as a predictor of hematogenous metastasis in human colorectal cancer | 7 | 1
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459 | 6 | 331 2000 TOXICOLOGY LETTERS 112():403-409
Paulsen JE Modulation by dietary factors in murine FAP models | 7 | 0
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460 | 1 | 339 2001 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 281(5):G1279-G1289
Bradham CA; Hatano E; Brenner DA Dominant-negative TAK1 induces c-Myc and G(0) exit in liver | 7 | 0
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461 | 1 | 363 2001 CANCER RESEARCH 61(4):1386-1391
Boudreau MD; Sohn KH; Rhee SH; Lee SW; Hunt JD; Hwang DH Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: Mediation through cyclooxygenase-independent pathways | 7 | 0
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462 | 13 | 366 2001 CANCER RESEARCH 61(5):2097-2104
Wagenaar RA; Crawford HC; Matrisian LM Stabilized beta-catenin immortalizes colonic epithelial cells | 7 | 2
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463 | 11 | 372 2001 CANCER RESEARCH 61(10):4197-4205
Szeto W; Jiang W; Tice DA; Rubinfeld B; Hollingshead PG; Fong SE; Dugger DL; Pham T; Yansura DG; Wong TA; Grimaldi JC; Corpuz RT; Singh JS; Frantz GD; Devaux B; Crowley CW; Schwall RH; Eberhard DA; Rastelli L; Polakis P; Pennica D Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid | 7 | 2
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464 | 2 | 427 2001 HISTOPATHOLOGY 39(2):141-149
Grabsch H; Takeno S; Noguchi T; Hommel G; Gabbert HE; Mueller W Different patterns of beta-catenin expression in gastric carcinomas: relationship with clinicopathological parameters and prognostic outcome | 7 | 2
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465 | 7 | 473 2001 JOURNAL OF CELL SCIENCE 114(7):1309-1319
Goichberg P; Shtutman M; Ben-Ze'ev A; Geiger B Recruitment of beta-catenin to cadherin-mediated intercellular adhesions is involved in myogenic induction | 7 | 0
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466 | 2 | 474 2001 JOURNAL OF CELLULAR BIOCHEMISTRY 81(2):262-277
Jaiswal AS; Narayan S Upstream stimulating factor-1 (USF1) and USF2 bind to and activate the promoter of the Adenomatous polyposis coli (APC) tumor suppressor gene | 7 | 1
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467 | 9 | 475 2001 JOURNAL OF CELLULAR PHYSIOLOGY 189(2):121-132
Pla P; Moore R; Morali OG; Grille S; Martinozzi S; Delmas V; Larue L Cadherins in neural crest cell development and transformation | 7 | 1
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468 | 5 | 483 2001 JOURNAL OF PATHOLOGY 193(4):427-432
Saldanha G The Hedgehog signalling pathway and cancer | 7 | 0
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469 | 7 | 487 2001 JOURNAL OF PATHOLOGY 195(2):222-228
Saito T; Oda Y; Tanaka K; Matsuda S; Tamiya S; Iwamoto Y; Tsuneyoshi M beta-catenin nuclear expression correlates with cyclin D1 overexpression in sporadic desmoid tumours | 7 | 2
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470 | 6 | 497 2001 MODERN PATHOLOGY 14(9):900-905
Sugimachi K; Taguchi K; Aishima S; Tanaka S; Shimada M; Kajiyama K; Sugimachi K; Tsuneyoshi M Altered expression of beta-catenin without genetic mutation in intrahepatic cholangiocarcinoma | 7 | 5
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471 | 1 | 550 2001 PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 69 69():47-79
Szyf M; Detich N Regulation of the DNA methylation machinery and its role in cellular transformation | 7 | 0
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472 | 27 | 556 2002 AMERICAN JOURNAL OF PATHOLOGY 160(4):1229-1238
Zhai Y; Wu R; Schwartz DR; Darrah D; Reed H; Kolligs FT; Nieman MT; Fearon ER; Cho KR Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas | 7 | 1
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473 | 13 | 559 2002 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 283(3):C811-C821
Venkiteswaran K; Xiao KY; Summers S; Calkins CC; Vincent PA; Pumiglia K; Kowalczyk AP Regulation of endothelial barrier function and growth by VE-cadherin, plakoglobin, and beta-catenin | 7 | 0
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474 | 5 | 585 2002 CANCER CELL 1(4):355-368
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476 | 4 | 603 2002 CIRCULATION RESEARCH 91(7):565-569
Patino WD; Mian OY; Hwang PM Serial analysis of gene expression - Technical considerations and applications to cardiovascular biology | 7 | 0
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477 | 2 | 613 2002 ENDOCRINOLOGY 143(3):898-908
Hsieh M; Johnson MA; Greenberg NM; Richards JS Regulated expression of Wnts and frizzleds at specific stages of follicular development in the rodent ovary | 7 | 0
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478 | 9 | 674 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(25):22692-22698
Schroeder JA; Adriance MC; McConnell EJ; Thompson MC; Pockaj B; Gendler SJ ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu Transgenic carcinomas | 7 | 5
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479 | 1 | 3 1998 BULLETIN DU CANCER 85(11):925-928
Jeanteur P The role of APC in colon cancer: zeroing in on MYC | 6 | 2
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480 | 2 | 85 1999 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 4(5):541-544
Kucerova D; Sloncova E; Tuhackova Z; Uhlirova M; Kos M; Sovova V Changes of E-cadherin and beta-catenin levels during induced differentiation of colorectal carcinoma cells | 6 | 0
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481 | 6 | 145 1999 TRENDS IN BIOCHEMICAL SCIENCES 24(12):M53-M56
McCormick F Signalling networks that cause cancer | 6 | 0
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482 | 3 | 175 2000 CANCER LETTERS 159(1):73-78
Murata M; Iwao K; Miyoshi Y; Nagasawa Y; Yabu M; Himeno S; Imanishi K; Ohsawa M; Wada H; Tominaga S; Shimano T; Kobayashi T; Nakamura Y Activation of the beta-catenin gene by interstitial deletions involving exon 3 as an early event in colorectal tumorigenesis | 6 | 4
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483 | 6 | 181 2000 CANCER RESEARCH 60(13):3354-3358
Kawasoe T; Furukawa Y; Daigo Y; Nishiwaki T; Ishiguro H; Fujita M; Satoh S; Miwa N; Nagasawa Y; Miyoshi Y; Ogawa M; Nakamura Y Isolation and characterization of a novel human gene, DRCTNNB1A, the expression of which is down-regulated by beta-catenin | 6 | 6
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484 | 3 | 246 2000 HUMAN GENE THERAPY 11(16):2261-2266
Watt FM Epidermal stem cells as targets for gene transfer | 6 | 0
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485 | 2 | 252 2000 INTERNATIONAL JOURNAL OF CANCER 87(1):5-11
Shimakage M; Kawahara K; Kikkawa N; Sasagawa T; Yutsudo M; Inoue H Down-regulation of drs mRNA in human colon adenocarcinomas | 6 | 0
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486 | 3 | 270 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(35):27266-27273
van Beest M; Dooijes D; van de Wetering M; Kjaerulff S; Bonvin A; Nielsen O; Clevers H Sequence-specific high mobility group box factors recognize 10-12-base pair minor groove motifs | 6 | 0
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487 | 6 | 280 2000 JOURNAL OF CELL SCIENCE 113(12):2129-2138
Naylor S; Smalley MJ; Robertson D; Gusterson BA; Edwards PAW; Dale TC Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium | 6 | 2
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488 | 2 | 285 2000 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 19(3):349-355
Ougolkov A; Mai M; Takahashi Y; Omote K; Bilim V; Shimizu A; Minamoto T Altered expression of beta-catenin and c-erbB-2 in early gastric cancer | 6 | 1
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489 | 9 | 286 2000 JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS 5(1):10-13
Petzelbauer P; Halama T; Groger M Endothelial adherens junctions | 6 | 0
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490 | 2 | 344 2001 BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY 15(5):821-833
Giercksky KE COX-2 inhibition and prevention of cancer | 6 | 0
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491 | 5 | 376 2001 CANCER RESEARCH 61(16):6297-6302
Yang WC; Velcich A; Mariadason J; Nicholas C; Corner G; Houston M; Edelmann W; Kucherlapati R; Holt PR; Augenlicht LH p21(WAF1/cip1) is an important determinant of intestinal cell response to sulindac in vitro and in vivo | 6 | 2
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492 | 7 | 383 2001 CANCER RESEARCH 61(22):8085-8088
Hao XP; Pretlow TG; Rao JS; Pretlow TP beta-catenin expression is altered in human colonic aberrant crypt foci | 6 | 2
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493 | 3 | 388 2001 CARCINOGENESIS 22(11):1885-1890
Koesters R; Hans MA; Benner A; Prosst R; Boehm J; Gahlen J; Doeberitz MVK Predominant mutation of codon 41 of the beta-catenin proto-oncogene in rat colon tumors induced by 1,2-dimethylhydrazine using a complete carcinogenic protocol | 6 | 0
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494 | 1 | 423 2001 GUT 48(5):660-666
Brown WA; Skinner SA; Malcontenti-Wilson C; Vogiagis D; O'Brien PE Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation | 6 | 1
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495 | 8 | 461 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(49):45833-45839
Galea MA; Eleftheriou A; Henderson BR ARM domain-dependent nuclear import of adenomatous polyposis coli protein is stimulated by the B56 alpha subunit of protein phosphatase 2A | 6 | 2
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496 | 1 | 495 2001 MODERN PATHOLOGY 14(1):29-39
Aust DE; Terdiman TP; Willenbucher RF; Chew K; Ferrell L; Florendo C; Molinaro-Clark A; Baretton GB; Lohrs U; Waldman FM Altered distribution of beta-catenin, and its binding proteins E-cadherin and APC, in ulcerative colitis-related colorectal cancers | 6 | 2
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497 | 10 | 508 2001 MOLECULAR CARCINOGENESIS 31(1):56-62
Uthoff SMS; Eichenberger MR; McAuliffe TL; Hamilton CJ; Galandiuk S Wingless-type frizzled protein receptor signaling and its putative role in human colon cancer | 6 | 3
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498 | 5 | 509 2001 MOLECULAR CARCINOGENESIS 31(2):68-73
Devereux TR; Stern MC; Flake GP; Yu MC; Zhang ZQ; London SJ; Taylor JA CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1 | 6 | 1
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499 | 4 | 527 2001 ONCOGENE 20(30):4007-4018
Shi YJ; Simmons MN; Seki T; Oh SP; Sugrue SP Change in gene expression subsequent to induction of Pnn/DRS/memA: increase in p21(cip1/waf1) | 6 | 0
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500 | 11 | 538 2001 ONCOLOGY RESEARCH 12(11-12):469-476
Miwa N; Furuse M; Tsukita S; Niikawa N; Nakamura Y; Furukawa Y Involvement of claudin-1 in the beta-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers | 6 | 3
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