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Identification of c-MYC as a target of the APC pathway
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW
SCIENCE 281 (5382): 1509-1512 SEP 4 1998
and the papers citing it.
Nodes: 919
Sorted by year, journal, volume, page.
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#Cited
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Nodes / AuthorsGCSLCS
5011501 2001 MOLECULAR AND CELLULAR BIOLOGY 21(2):575-594
Reeves R; Edberg DD; Li Y
Architectural transcription factor HMGI(Y) promotes tumor progression and mesenchymal transition of human epithelial cells
232
5028502 2001 MOLECULAR AND CELLULAR BIOLOGY 21(3):902-915
Goruppi S; Chiaruttini C; Ruaro ME; Varnum B; Schneider C
Gas6 induces growth, beta-catenin stabilization, and T-cell factor transcriptional activation in contact-inhibited C57 mammary cells
143
50310503 2001 MOLECULAR AND CELLULAR BIOLOGY 21(4):1370-1383
Crawford HC; Fingleton B; Gustavson MD; Kurpios N; Wagenaar RA; Hassell JA; Matrisian LM
The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors
356
50413504 2001 MOLECULAR AND CELLULAR BIOLOGY 21(17):5857-5868
Danilkovitch-Miagkova A; Miagkov A; Skeel A; Nakaigawa N; Zbar B; Leonard EJ
Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway
110
5055505 2001 MOLECULAR AND CELLULAR BIOLOGY 21(19):6626-6639
Miller LD; Park KS; Guo QBM; Alkharouf NW; Malek RL; Lee NH; Liu ET; Cheng SY
Silencing of Wnt signaling and activation of multiple metabolic pathways in response to thyroid hormone-stimulated cell proliferation
110
50623506 2001 MOLECULAR AND CELLULAR BIOLOGY 21(20):6768-6781
Sadot E; Geiger B; Oren M; Ben-Ze'ev A
Down-regulation of beta-catenin by activated p53
268
5077507 2001 MOLECULAR AND CELLULAR BIOLOGY 21(23):8143-8156
Zhang F; White RL; Neufeld KL
Cell density and phosphorylation control the subcellular localization of adenomatous polyposis coli protein
135
50810508 2001 MOLECULAR CARCINOGENESIS 31(1):56-62
Uthoff SMS; Eichenberger MR; McAuliffe TL; Hamilton CJ; Galandiuk S
Wingless-type frizzled protein receptor signaling and its putative role in human colon cancer
63
5095509 2001 MOLECULAR CARCINOGENESIS 31(2):68-73
Devereux TR; Stern MC; Flake GP; Yu MC; Zhang ZQ; London SJ; Taylor JA
CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1
61
5101510 2001 MOLECULAR CARCINOGENESIS 31(4):192-203
Roy D; Calaf G; Hei TK
Profiling of differentially expressed genes induced by high linear energy transfer radiation in breast epithelial cells
30
5111511 2001 MOLECULAR CELL 7(3):673-682
Yu J; Zhang L; Hwang PM; Kinzler KW; Vogelstein B
PUMA induces the rapid apoptosis of colorectal cancer cells
1372
5122512 2001 MOLECULAR CELL 7(5):915-926
Matsuzawa S; Reed JC
Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses
8420
5136513 2001 NATURE 411(6835):349-354
Taipale J; Beachy PA
The Hedgehog and Wnt signaling pathways in cancer
9811
51413514 2001 NATURE CELL BIOLOGY 3(9):793-801
Ryo A; Nakamura M; Wulf G; Liou YC; Lu KP
Pin 1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
319
5158515 2001 NATURE GENETICS 28(1):53-57
Hovanes K; Li TWH; Munguia JE; Truong T; Milovanovic T; Marsh JL; Holcombe RF; Waterman ML
beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer
5526
5161516 2001 NATURE GENETICS 28(2):165-168
Waikel RL; Kawachi Y; Waikel PA; Wang XJ; Roop DR
Deregulated expression of c-Myc depletes epidermal stem cells
245
5176517 2001 NATURE IMMUNOLOGY 2(8):691-697
Ioannidis V; Beermann F; Clevers H; Held W
The beta-catenin-TCF-I pathway ensures CD4(+)CD8(+) thymocyte survival
226
51816518 2001 NATURE REVIEWS CANCER 1(1):55-67
Fodde R; Smits R; Clevers H
APC, signal transduction and genetic instability in colorectal cancer
465
5195519 2001 NATURE STRUCTURAL BIOLOGY 8(12):1048-1052
Graham TA; Ferkey DM; Mao F; Kimelman D; Xu WQ
Tcf4 can specifically recognize beta-catenin using alternative conformations
92
5208520 2001 NEOPLASIA 3(1):4-9
Kato T; Satoh S; Okabe H; Kitahara O; Ono K; Kihara C; Tanaka T; Tsunoda T; Yamaoka Y; Nakamura Y; Furukawa Y
Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis
50
5214521 2001 NUCLEIC ACIDS RESEARCH 29(7):1410-1419
Brantjes H; Roose J; van de Wetering M; Clevers H
All Tcf HMG box transcription factors interact with Groucho-related co-repressors
3912
5225522 2001 ONCOGENE 20(1):133-140
Tan C; Costello P; Sanghera J; Dominguez D; Baulida J; de Herreros AG; Dedhar S
Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells
357
5233523 2001 ONCOGENE 20(5):626-633
Zwerner JP; May WA
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors
200
52411524 2001 ONCOGENE 20(5):645-653
Dihlmann S; Siermann A; Doeberitz MV
The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/TCF-4 signaling
100
5252525 2001 ONCOGENE 20(22):2727-2736
Baba M; Hirai S; Kawakami S; Kishida T; Sakai N; Kaneko S; Yao M; Shuin T; Kubota Y; Hosaka M; Ohno S
Tumor suppressor protein VHL is induced at high cell density and mediates contact inhibition of cell growth
140
5263526 2001 ONCOGENE 20(25):3247-3257
Landesman-Bollag E; Romieu-Mourez R; Song DH; Sonenshein GE; Cardiff RD; Seldin DC
Protein kinase CK2 in mammary gland tumorigenesis
300
5274527 2001 ONCOGENE 20(30):4007-4018
Shi YJ; Simmons MN; Seki T; Oh SP; Sugrue SP
Change in gene expression subsequent to induction of Pnn/DRS/memA: increase in p21(cip1/waf1)
60
5287528 2001 ONCOGENE 20(35):4884-4890
Dang DT; Mahatan CS; Dang LH; Agboola IA; Yang VW
Expression of the gut-enriched Kruppel-like factor (Kruppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2
160
52911529 2001 ONCOGENE 20(36):5062-5066
Ishiguro H; Tsunoda T; Tanaka T; Fujii Y; Nakamura Y; Furukawa Y
Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney
43
53012530 2001 ONCOGENE 20(37):5093-5099
Michaelson JS; Leder P
beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland
2312
53112531 2001 ONCOGENE 20(40):5595-5610
Boxer LM; Dang CV
Translocations involving c-myc and c-myc function
282
5326532 2001 ONCOGENE 20(41):5810-5817
Ugolini F; Charafe-Jauffret E; Bardou VJ; Geneix J; Adelaide J; Labat-Moleur F; Penault-Llorca F; Longy M; Jacquemier J; Birnbaum D; Pebusque MJ
WNT pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type
144
5336533 2001 ONCOGENE 20(42):5972-5981
Saadi-Kheddouci S; Berrebi D; Romagnolo B; Cluzeaud F; Peuchmaur M; Kahn A; Vandewalle A; Perret C
Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene
130
5349534 2001 ONCOGENE 20(43):6250-6257
Marotta A; Tan C; Gray V; Malik S; Gallinger S; Sanghera J; Dupuis B; Owen D; Dedhar S; Salh B
Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis
102
5358535 2001 ONCOGENE 20(52):7645-7657
Hollmann CA; Kittrell FS; Medina D; Butel JS
Wnt-1 and int-2 mammary oncogene effects on the beta-catenin pathway in immortalized mouse mammary epithelial cells are not sufficient for tumorigenesis
00
5366536 2001 ONCOLOGY 61(2):156-161
Saeki H; Tanaka S; Tokunaga E; Kawaguchi H; Ikeda Y; Maehara Y; Sugimachi K
Genetic alterations in the human Tcf-4 gene in Japanese patients with sporadic gastrointestinal cancers with microsatellite instability
21
53710537 2001 ONCOLOGY 61(3):226-233
Utsunomiya T; Doki Y; Takemoto H; Shiozaki H; Yano M; Sekimoto M; Tamura S; Yasuda T; Fujiwara Y; Monden M
Correlation of beta-catenin and cyclin D1 expression in colon cancers
43
53811538 2001 ONCOLOGY RESEARCH 12(11-12):469-476
Miwa N; Furuse M; Tsukita S; Niikawa N; Nakamura Y; Furukawa Y
Involvement of claudin-1 in the beta-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers
63
5398539 2001 PATHOLOGY INTERNATIONAL 51(9):680-685
Miyake N; Maeta H; Horie S; Kitamura Y; Nanba E; Kobayashi K; Terada T
Absence of mutations in the beta-catenin and adenomatous polyposis coli genes in papillary and follicular thyroid carcinomas
11
5407540 2001 PEDIATRIC AND DEVELOPMENTAL PATHOLOGY 4(4):351-357
Eberhart CG; Argani P
Wnt signaling in human development: Beta-catenin nuclear translocation in fetal lung, kidney, placenta, capillaries, adrenal, and cartilage
51
5414541 2001 PEDIATRIC SURGERY INTERNATIONAL 17(7):508-512
Udatsu Y; Kusafuka T; Kuroda S; Miao J; Okada A
High frequency of beta-catenin mutations in hepatoblastoma
52
5422542 2001 PHYSIOLOGICAL GENOMICS 7(2):105-114
Kuhn I; Bartholdi MF; Salamon H; Feldman RI; Roth RA; Johnson PH
Identification of AKT-regulated genes in inducible MERAkt cells
30
5432543 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(3):992-999
Chen CR; Kang YB; Massague J
Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program
645
5443544 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2598-2603
Park BH; Vogelstein B; Kinzler KW
Genetic disruption of PPAR delta decreases the tumorigenicity of human colon cancer cells
453
5454545 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(8):4646-4651
Kolli S; Buchmann AM; Williams J; Weitzman S; Thimmapaya B
Antisense-mediated depletion of p300 in human cells leads to premature G(1) exit and up-regulation of c-MYC
81
54613546 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(18):10356-10361
Brabletz T; Jung A; Reu S; Porzner M; Hlubek F; Kunz-Schughart LA; Knuechel R; Kirchner T
Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
309
5478547 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(19):10863-10868
Xia XF; Qian S; Soriano S; Wu Y; Fletcher AM; Wang XJ; Koo EH; Wu XW; Zheng H
Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis
267
5484548 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(26):14973-14978
Yan D; Wiesmann M; Rohan M; Chan V; Jefferson AB; Guo LD; Sakamoto D; Caothien RH; Fuller JH; Reinhard C; Garcia PD; Randazzo FM; Escobedo J; Fantl WJ; Williams LT
Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta-catenin signaling is activated in human colon tumors
137
5492549 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(26):15203-15208
Nacht M; Dracheva T; Gao YH; Fujii T; Chen YD; Player A; Akmaev V; Cook B; Dufault M; Zhang M; Zhang W; Guo MZ; Curran J; Han S; Sidransky D; Buetow K; Madden SL; Jen J
Molecular characteristics of non-small cell lung cancer
222
5501550 2001 PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 69 69():47-79
Szyf M; Detich N
Regulation of the DNA methylation machinery and its role in cellular transformation
70
5515551 2001 SEMINARS IN CANCER BIOLOGY 11(3):219-225
Kucherlapati R; Lin DP; Edelmann W
Mouse models for human familial adenomatous polyposis
21
55215552 2001 VIRCHOWS ARCHIV 439(6):725-751
Van Aken E; De Wever O; da Rocha ASC; Mareel M
Defective E-cadherin/catenin complexes in human cancer
290
55315553 2002 ADVANCES IN CANCER RESEARCH, VOL 84 84():203-229
Manoukian AS; Woodgett JR
Role of glycogen synthase kinase-3 in cancer: Regulation by Wnts and other signaling pathways
110
5546554 2002 AMERICAN JOURNAL OF GASTROENTEROLOGY 97(3):542-553
Husain SS; Szabo IL; Tarnawski AS
NSAID inhibition of GI cancer growth: Clinical implications and molecular mechanisms of action
80
55526555 2002 AMERICAN JOURNAL OF PATHOLOGY 160(2):389-401
Wong NACS; Pignatelli M
beta-catenin - A linchpin in colorectal carcinogenesis?
335
55627556 2002 AMERICAN JOURNAL OF PATHOLOGY 160(4):1229-1238
Zhai Y; Wu R; Schwartz DR; Darrah D; Reed H; Kolligs FT; Nieman MT; Fearon ER; Cho KR
Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas
71
5575557 2002 AMERICAN JOURNAL OF PATHOLOGY 160(4):1361-1369
Abraham SC; Klimstra DS; Wilentz RE; Yeo CJ; Conlon K; Brennan M; Cameron JL; Wu TT; Hruban RH
Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor beta-catenin mutations
93
5584558 2002 AMERICAN JOURNAL OF PATHOLOGY 161(5):1735-1742
Abraham SC; Park SJ; Mugartegui L; Hamilton SR; Wu TT
Sporadic fundic gland polyps with epithelial dysplasia - Evidence for preferential targeting for mutations in the adenomatous polyposis coli gene
10
55913559 2002 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 283(3):C811-C821
Venkiteswaran K; Xiao KY; Summers S; Calkins CC; Vincent PA; Pumiglia K; Kowalczyk AP
Regulation of endothelial barrier function and growth by VE-cadherin, plakoglobin, and beta-catenin
70
5602560 2002 ANNALES DE PATHOLOGIE 22(4):277-288
Piard F; Martin L; Chapusot C; Ponnelle T; Faivre J
Genetic pathways in colorectal cancer: interest for the pathologist
00
56111561 2002 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 3():101-128
Grady WM; Markowitz SD
Genetic and epigenetic alterations in colon cancer
90
5625562 2002 ANTICANCER RESEARCH 22(4):2215-2220
Dobbie Z; Muller PY; Heinimann K; Albrecht C; D'Orazio D; Bendik I; Muller H; Bauerfeind P
Expression of COX-2 and Wnt pathway genes in adenomas of familial adenomatous polyposis patients treated with meloxicam
30
5635563 2002 ANTICANCER RESEARCH 22(6A):3409-3414
D'Orazio D; Muller PY; Heinimann K; Albrecht C; Bendik I; Herzog U; Tondelli P; Bauerfeind P; Muller H; Dobbie Z
Overexpression of Wnt target genes in adenomas of familial adenomatous polyposis patients
00
5646564 2002 ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE 126(9):1071-1078
Sakamoto A; Oda Y; Adachi T; Saito T; Tamiya S; Iwamoto Y; Tsuneyoshi M
beta-Catenin accumulation and gene mutation in exon 3 in dedifferentiated liposarcoma and malignant fibrous histiocytoma
11
5655565 2002 BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY 16(2):171-185
Tejpar S; Van Cutsem E
Molecular and genetic defects in colorectal tumorigenesis
00
5663566 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 292(1):195-199
Dietrich C; Scherwat J; Faust D; Oesch F
Subcellular localization of beta-catenin is regulated by cell density
43
5675567 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 299(5):744-750
Meredith JE; Wang Q; Mitchell TJ; Olson RE; Zaczek R; Stern AM; Seiffert D
gamma-Secretase activity is not involved in presenilin-mediated regulation of beta-catenin
00
5683568 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 299(5):806-812
Lim HW; Lee JE; Shin SJ; Lee YE; Oh SH; Park JY; Seong JK; Park JS
Identification of differentially expressed mRNA during pancreas regeneration of rat by mRNA differential display
10
56911569 2002 BIOCHEMICAL JOURNAL 367():723-728
Chtarbova S; Nimmrich I; Erdmann S; Herter P; Renner M; Kitajewski J; Muller O
Murine Nr4a1 and Herpud1 are up-regulated by Wnt-1, but the homologous human genes are independent from beta-catenin activation
00
57015570 2002 BIOCHEMICAL PHARMACOLOGY 64(9):1325-1336
Li H; Liu L; David ML; Whitehead CM; Chen M; Fetter JR; Sperl GJ; Pamukcu R; Thompson WJ
Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation
51
5716571 2002 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1577(1):81-92
Ballarino M; Marchioni M; Carnevali F
The Xenopus laevis beta TrCP gene: genomic organization, alternative splicing, 5 ' and 3 ' region characterization and comparison of its structure with that of human beta TrCP genes
20
5725572 2002 BIOESSAYS 24(1):54-64
Johnston LA; Gallant P
Control of growth and organ size in Drosophila
140
57316573 2002 BIOLOGICAL CHEMISTRY 383(2):255-261
Brantjes H; Barker N; van Es J; Clevers H
TCF: Lady justice casting the final verdict on the outcome of Wnt signalling
202
57412574 2002 BIOLOGICAL RESEARCH 35(2):277-286
Hendriks B; Reichmann E
Wnt signaling: A complex issue
20
57511575 2002 BIOTECHNIQUES 33(5):1126-+
Zhou L; An N; Jiang W; Haydon R; Cheng H; Zhou Q; Breyer B; Feng T; He TC
Fluorescence-based functional assay for Wnt/beta-catenin signaling activity
11
57617576 2002 BLOOD 100(3):982-990
Chung EJ; Hwang SG; Nguyen P; Lee S; Kim JS; Kim JW; Henkart PA; Bottaro DP; Soon L; Bonvini P; Lee SJ; Karp JE; Oh HJ; Rubin JS; Trepel JB
Regulation of leukemic cell adhesion, proliferation, and survival by beta-catenin
11
5778577 2002 BREAST CANCER RESEARCH 5(1):16-22
Rossi S; Loda M
The role of the ubiquitination-proteasome pathway in breast cancer - Use of mouse models for analyzing ubiquitination processes
00
5789578 2002 BRITISH JOURNAL OF CANCER 86(7):1124-1129
Chiang JM; Chou YHW; Chen TC; Ng KF; Lin JL
Nuclear beta-catenin expression is closely related to ulcerative growth of colorectal carcinoma
00
5791579 2002 BRITISH JOURNAL OF SURGERY 89(7):845-860
Leslie A; Carey FA; Pratt NR; Steele RJC
The colorectal adenoma-carcinoma sequence
61
5804580 2002 BRITISH MEDICAL BULLETIN 64():27-43
Fearnhead NS; Wilding JL; Bodmer WF
Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis
10
58110581 2002 CANCER 95(12):2479-2486
Cheah PY; Choo PH; Yao J; Eu KW; Seow-Choen F
A survival-stratification model of human colorectal carcinomas with beta-catenin and p27(kip1)
00
5822582 2002 CANCER BIOLOGY & THERAPY 1(1):58-63
Termuhlen PM; Sweeney-Gotsch BM; Berman RS; Ellis LM; Bucana C; Shen Y; Cleary KR; McConkey DJ
Increased apoptosis in metastatic human colonic adenocarcinomas
00
5833583 2002 CANCER BIOLOGY & THERAPY 1(6):640-645
Coyle-Rink J; Del Valle L; Sweet T; Khalili K; Amini S
Developmental expression of Wnt signaling factors in mouse brain
00
58418584 2002 CANCER CELL 1(2):145-155
Kolligs FT; Nieman MT; Winer I; Hu G; Van Mater D; Feng Y; Smith IM; Wu R; Zhai YL; Cho KR; Fearon ER
ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation
118
5855585 2002 CANCER CELL 1(4):355-368
Philipp-Staheli J; Kim KH; Payne SR; Gurley KE; Liggitt D; Longton G; Kemp CJ
Pathway-specific tumor suppression: Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice
70
58613586 2002 CANCER CELL 1(4):369-379
Patturajan M; Nomoto S; Sommer M; Fomenkov A; Hibi K; Zangen R; Poliak N; Califano J; Trink B; Ratovitski E; Sidransky D
Delta Np63 induces beta-catenin nuclear accumulation and signaling
101
58711587 2002 CANCER CELL 2(4):323-334
Deng JO; Miller SA; Wang HY; Xia WY; Wen Y; Zhou BHP; Li Y; Lin SY; Hung MC
beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer
31
5881588 2002 CANCER GENETICS AND CYTOGENETICS 135(1):48-56
Moritake H; Sugimoto T; Asada Y; Yoshida MA; Maehara Y; Epstein AL; Kuroda H
Newly established clear cell sarcoma (malignant melanoma of soft parts) cell line expressing melanoma-associated Melan-A antigen and overexpressing C-MYC oncogene
10
5893589 2002 CANCER LETTERS 180(2):107-119
Strieder V; Lutz W
Regulation of N-myc expression in development and disease
20
5902590 2002 CANCER LETTERS 181(2):125-164
Marsh DJ; Zori RT
Genetic insights into familial cancers - update and recent discoveries
40
5912591 2002 CANCER LETTERS 183(1):31-41
Suzui M; Okuno M; Tanaka T; Nakagama H; Moriwaki H
Enhanced colon carcinogenesis induced by azoxymethane in min mice occurs via a mechanism independent of beta-catenin mutation
10
5927592 2002 CANCER LETTERS 183(1):95-101
Howng SL; Wu CH; Cheng TS; Sy WD; Lin PCK; Wang CH; Hong YR
Differential expression of Wnt genes, beta-catenin and E-cadherin in human brain tumors
10
59315593 2002 CANCER RESEARCH 62(1):277-282
Mizushima T; Nakagawa H; Kamberov YG; Wilder EL; Klein PS; Rustgi AK
Wnt-1 but not epidermal growth factor induces beta-catenin/T-cell factor-dependent transcription in esophageal cancer cells
32
59410594 2002 CANCER RESEARCH 62(7):1971-1977
Harada N; Miyoshi H; Murai N; Oshima H; Tamai Y; Oshima M; Taketo MM
Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin
76
59511595 2002 CANCER RESEARCH 62(12):3503-3506
Clements WM; Wang J; Sarnaik A; Kim OJ; MacDonald J; Fenoglio-Preiser C; Groden J; Lowy AM
beta-catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer
85
5964596 2002 CANCER RESEARCH 62(16):4562-4565
Wilding J; Straub J; Bee J; Churchman M; Bodmer W; Dickson C; Tomlinson I; Ilyas M
Cyclin D1 is not an essential target of beta-catenin signaling during intestinal tumorigenesis, but it may act as a modifier of disease severity in multiple intestinal neoplasia (Min) mice
31
59717597 2002 CANCER RESEARCH 62(20):5939-5954
Hoglund M; Gisselsson D; Hansen GB; Sall T; Mitelman F; Nilbert M
Dissecting karyotypic patterns in colorectal tumors: Two distinct but overlapping pathways in the adenoma-carcinoma transition
30
5985598 2002 CANCER RESEARCH 62(21):6006-6010
Wilson AJ; Velcich A; Arango D; Kurland AR; Shenoy SM; Pezo RC; Levsky JM; Singer RH; Augenlicht LH
Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention
40
5994599 2002 CARCINOGENESIS 23(6):1065-1070
Fenton JI; Wolff MS; Orth MW; Hord NG
Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype
20
60013600 2002 CELL 111(2):241-250
van de Wetering M; Sancho E; Verweij C; de Lau W; Oving I; Hurlstone A; van der Horn K; Batlle E; Coudreuse D; Haramis AP; Tion-Pon-Fong M; Moerer P; van den Born M; Soete G; Pals S; Eilers M; Medema R; Clevers H
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
590

#Cited
nodes
Nodes / AuthorsGCSLCS
6011601 2002 CELL DEATH AND DIFFERENTIATION 9(5):513-526
Yamakawa-Karakida N; Sugita K; Inukai T; Goi K; Nakamura M; Uno K; Sato H; Kagami K; Barker N; Nakazawa S
Ligand activation of peroxisome proliferator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity
80
6021602 2002 CELLULAR SIGNALLING 14(4):351-358
Pauley CJ; Ledwith BJ; Kaplanski C
Peroxisome proliferators activate growth regulatory pathways largely via peroxisome proliferator-activated receptor alpha-independent mechanisms
20
6034603 2002 CIRCULATION RESEARCH 91(7):565-569
Patino WD; Mian OY; Hwang PM
Serial analysis of gene expression - Technical considerations and applications to cardiovascular biology
70
60410604 2002 CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 41(1):11-28
Mason MD; Davies G; Jiang WG
Cell adhesion molecules and adhesion abnormalities in prostate cancer
10
60518605 2002 CURRENT OPINION IN GASTROENTEROLOGY 18(1):53-59
Waterman ML
Expression of lymphoid enhancer factor/T-cell factor proteins in colon cancer
00
6064606 2002 CURRENT OPINION IN STRUCTURAL BIOLOGY 12(6):761-767
Pearl LH; Barford D
Regulation of protein kinases in insulin, growth factor and Wnt signalling
20
60713607 2002 DEVELOPMENT 129(1):95-109
Niemann C; Owens DM; Hulsken J; Birchmeier W; Watt FM
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c-myc is a downstream target of the Smad pathway
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Disulfide bond assignments of secreted frizzled-related protein-1 provide insights about frizzled homology and netrin modules
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Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes
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IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin
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Endostatin causes G(1) arrest of endothelial cells through inhibition of cyclin D1
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Casein kinase I and casein kinase II differentially regulate Axin function in Wnt and JNK pathways
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Glucocorticoids inhibit cell cycle progression in differentiating osteoblasts via glycogen synthase kinase-3 beta
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Liganded androgen receptor interaction with beta-catenin - Nuclear co-localization and modulation of transcriptional activity in neuronal cells
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Activation of AXIN2 expression by beta-catenin-T cell factor - A feedback repressor pathway regulating Wnt signaling
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ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu Transgenic carcinomas
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Acetylation of beta-catenin by CREB-binding protein (CBP)
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Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta-catenin signaling
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Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells
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Epidermal stem cells
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Anticancer drugs-induced apoptotic cell death in leukemia cells is associated with proteolysis of beta-catenin
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Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers
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Cadherins and NCAM as potential targets in metal toxicity
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beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis
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beta-catenin mutations in sporadic fundic gland polyps
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E-cadherin mediates MMP down-regulation in highly invasive bronchial tumor cells
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Gastrin-induced gastric adenocarcinoma growth is mediated through cyclin D1
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C-MYC gene amplification in different stages of oesophageal squamous cell carcinoma: Prognostic value in relation to treatment modality
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PECAM-1 promotes beta-catenin accumulation and stimulates endothelial cell proliferation
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Nemo-like kinase induces apoptosis in DLD-1 human colon cancer cells
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Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine
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Search for a common mechanism of mood stabilizers
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Polyamines as modifiers of genetic risk factors in human intestinal cancers
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Caught up in a Wnt storm: Wnt signaling in cancer
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A protein knockdown strategy to study the function of beta-catenin in tumorigenesis
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What can digital transcript profiling reveal about human cancers?
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beta-catenin: a transforming actor on many stages
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Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer
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Reduced expression of Axin correlates with tumour progression of oesophageal squamous cell carcinoma
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Characterisation of integrin-linked kinase signalling in sporadic human colon cancer
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No major tumorigenic role for beta-catenin in serrated as opposed to conventional colorectal adenomas
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Expression of beta-catenin in basal cell carcinoma
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Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity
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Endostatin action and intracellular signaling: beta-catenin as a potential target?
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Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways
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Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor beta-induced repression of c-myc
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Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation
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Transactivation of vimentin by beta-catenin in human breast cancer cells
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Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas
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beta-catenin regulates vascular endothelial growth factor expression in colon cancer
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Regulation of caspase expression and apoptosis by adenomatous polyposis coli
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7916791 2003 CANCER RESEARCH 63(15):4547-4551
Uematsu K; Kanazawa S; You L; He B; Xu ZD; Li K; Peterlin BM; McCormick F; Jablons DM
Wnt pathway activation in mesothelioma: Evidence of dishevelled overexpression and transcriptional activity of beta-catenin
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Seike M; Kondo T; Mori Y; Gemma A; Kudoh S; Sakamoto M; Yamada T; Hirohashi S
Proteomic analysis of intestinal epithelial cells expressing stabilized beta-catenin
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Siu IM; Lal A; Blankenship JR; Aldosari N; Riggins GJ
c-myc promoter activation in medulloblastoma
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Bertolino P; Tong WM; Herrera PL; Casse H; Zhang CX; Wang ZQ
Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice
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7957795 2003 CANCER RESEARCH 63(16):4990-4996
Yang WC; Bancroft L; Nicholas C; Lozonschi I; Augenlicht LH
Targeted inactivation of p27(kip1) is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a western-style high-risk diet
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7966796 2003 CANCER RESEARCH 63(19):6116-6120
Shimokawa T; Furukawa Y; Sakai M; Li MH; Miwa N; Lin YM; Nakamura Y
Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex
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7973797 2003 CANCER RESEARCH 63(19):6212-6220
Gatenby RA; Vincent TL
An evolutionary model of carcinogenesis
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7983798 2003 CANCER RESEARCH 63(19):6244-6251
Ayala G; Wang DG; Wulf G; Frolov A; Li R; Sowadski J; Wheeler TM; Lu KP; Bao L
The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer
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7995799 2003 CANCER RESEARCH 63(20):6626-6634
Chen DH; Xu WD; Bales E; Colmenares C; Conacci-Sorrell M; Ishii S; Stavnezer E; Campisi J; Fisher DE; Ben-Ze'ev A; Medrano EE
SKI activates Wnt/beta-catenin signaling in human melanoma
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Up-regulation and nuclear localization of beta-catenin in endometrial carcinoma in response to progestrone therapy
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The zinc-finger protein CNBP is required for forebrain formation in the mouse
11
8233823 2003 DEVELOPMENT GROWTH & DIFFERENTIATION 45(2):121-128
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Nuclear localization of beta-catenin in vegetal pole cells during early embryogenesis of the starfish Asterina pectinifera
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A role for Wnt/beta-catenin signaling in lens epithelial differentiation
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8262826 2003 DEVELOPMENTAL CELL 4(6):827-839
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The protooncogene c-Myc is an essential regulator of neural crest formation in Xenopus
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Real-time analysis of beta- and gamma-catenin mRNA expression in ret/PTC-1 activated and nonactivated thyroid tissues
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Structural basis for recruitment of glycogen synthase kinase 3 beta to the axin-APC scaffold complex
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beta-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and lineage specification
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Molecular cloning, developmental expression, promoter analysis and functional characterization of the mouse CNBP gene
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Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
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beta-Catenin nuclear localization is associated with grade in ovarian serous carcinoma
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EBP50, a beta-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma
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Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cells
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Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter
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Negative regulation of beta-catenin signaling by tyrosine phosphatase SHP-1 in intestinal epithelial cells
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A direct beta-catenin-independent interaction between androgen receptor and T cell factor 4
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The Wnt signaling pathway and its role in tumor development
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beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion
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Up-regulation and overproduction of DVL-1, the human counterpart of the Drosophila dishevelled gene, in cervical squamous cell carcinoma
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Enantiospecific formal total synthesis of the tumor and GSK-3 beta inhibiting alkaloid, (-)-agelastatin A
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WNT7a induces E-cadherin in lung cancer cells
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Expression of potential beta-catenin targets, cyclin D1, c-Jun, c-Myc, E-cadherin, and EGFR in chemically induced hepatocellular neoplasms from B6C3F1 mice
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Transcriptional repression by Myc
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