HistCite - Trojanowski w/citing papers

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#	Date / Author / Journal	LCS	GCS	LCR	CR
1	5270 Spillantini MG, Schmidt ML, Lee VMY, Trojanowski JQ, Jakes R, et al. alpha-synuclein in Lewy bodies NATURE. 1997 AUG 28; 388 (6645): 839-840	1896	1896	2	13
2	6083 Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, et al. Association of missense and 5 '-splice-site mutations in tau with the inherited dementia FTDP-17 NATURE. 1998 JUN 18; 393 (6686): 702-705	1368	1369	12	28
3	5735 Kruger R, Kuhn W, Muller T, Woitalla D, Graeber M, et al. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease NATURE GENETICS. 1998 FEB; 18 (2): 106-108	1324	1597	1	10
4	1893 Lee VMY, BALIN BJ, OTVOS L, Trojanowski JQ A68 - A MAJOR SUBUNIT OF PAIRED HELICAL FILAMENTS AND DERIVATIZED FORMS OF NORMAL-TAU SCIENCE. 1991 FEB 8; 251 (4994): 675-678	1000	1000	9	35
5	9363 Freed CR, Greene PE, Breeze RE, Tsai WY, DuMouchel W, et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. NEW ENGLAND JOURNAL OF MEDICINE. 2001 MAR 8; 344 (10): 710-719	902	902	1	38
6	6569 Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, et al. Frontotemporal lobar degeneration - A consensus on clinical diagnostic criteria NEUROLOGY. 1998 DEC; 51 (6): 1546-1554	818	1661	2	48
7	8982 Lee VMY, Goedert M, Trojanowski JQ Neurodegenerative tauopathies ANNUAL REVIEW OF NEUROSCIENCE. 2001; 24: 1121-1159	807	807	178	256
8	1444 GOEDERT M, SPILLANTINI MG, JAKES R, RUTHERFORD D, CROWTHER RA MULTIPLE ISOFORMS OF HUMAN MICROTUBULE-ASSOCIATED PROTEIN-TAU - SEQUENCES AND LOCALIZATION IN NEUROFIBRILLARY TANGLES OF ALZHEIMERS- DISEASE NEURON. 1989 OCT; 3 (4): 519-526	785	998	2	31
9	12876 Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, et al. alpha-synuclein locus triplication causes Parkinson's disease SCIENCE. 2003 OCT 31; 302 (5646): 841-841	754	1059	3	5
10	6009 Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998 MAY 26; 95 (11): 6469-6473	733	859	13	36
#	Date / Author / Journal	LCS	GCS	LCR	CR
11	6089 Spillantini MG, Murrell JR, Goedert M, Farlow MR, Klug A, et al. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998 JUN 23; 95 (13): 7737-7741	728	752	28	48
12	8074 Masliah E, Rockenstein E, Veinbergs I, Mallory M, Hashimoto M, et al. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: Implications for neurodegenerative disorders SCIENCE. 2000 FEB 18; 287 (5456): 1265-1269	706	838	10	24
13	16370 McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, et al. Diagnosis and management of dementia with Lewy bodies - Third report of the DLB consortium NEUROLOGY. 2005 DEC 27; 65 (12): 1863-1872	706	706	36	105
14	5911 Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism NATURE. 1998 APR 9; 392 (6676): 605-608	703	1743	5	27
15	5856 Baba M, Nakajo S, Tu PH, Tomita T, Nakaya K, et al. Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with lewy bodies AMERICAN JOURNAL OF PATHOLOGY. 1998 APR; 152 (4): 879-884	667	667	13	34
16	6021 Poorkaj P, Bird TD, Wijsman E, Nemens E, Garruto RM, et al. Tau is a candidate gene for chromosome 17 frontotemporal dementia ANNALS OF NEUROLOGY. 1998 JUN; 43 (6): 815-825	663	698	9	42
17	8165 Feany MB, Bender WW A Drosophila model of Parkinson's disease NATURE. 2000 MAR 23; 404 (6776): 394-398	644	835	11	30
18	8855 Giasson BI, Duda JE, Murray IVJ, Chen QP, Souza JM, et al. Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions SCIENCE. 2000 NOV 3; 290 (5493): 985-989	638	638	18	36
19	17811 Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis SCIENCE. 2006 OCT 6; 314 (5796): 130-133	631	631	16	27
20	11057 Hardy J, Selkoe DJ Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics SCIENCE. 2002 JUL 19; 297 (5580): 353-356	623	2710	16	91
#	Date / Author / Journal	LCS	GCS	LCR	CR
21	9991 McKhann GM, Albert MS, Grossman M, Miller B, Dickson D, et al. Clinical and pathological diagnosis of Frontotemporal Dementia - Report of the work group on Frontotemporal Dementia and Pick's disease ARCHIVES OF NEUROLOGY. 2001 NOV; 58 (11): 1803-1809	598	599	15	57
22	13393 Zarranz JJ, Alegre J, Gomez-Esteban JC, Lezcano E, Ros R, et al. The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia ANNALS OF NEUROLOGY. 2004 FEB; 55 (2): 164-173	555	646	27	51
23	6485 Conway KA, Harper JD, Lansbury PT Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease NATURE MEDICINE. 1998 NOV; 4 (11): 1318-1320	533	621	10	22
24	12066 Braak H, Del Tredici K, Rub U, de Vos RAI, Steur ENHJ, et al. Staging of brain pathology related to sporadic Parkinson's disease NEUROBIOLOGY OF AGING. 2003 MAR-APR; 24 (2): 197-211	515	1133	19	72
25	2210 GOEDERT M, SPILLANTINI MG, CAIRNS NJ, CROWTHER RA TAU-PROTEINS OF ALZHEIMER PAIRED HELICAL FILAMENTS - ABNORMAL PHOSPHORYLATION OF ALL 6 BRAIN ISOFORMS NEURON. 1992 JAN; 8 (1): 159-168	508	603	10	37
26	10518 Auluck PK, Chan HYE, Trojanowski JQ, Lee VMY, Bonini NM Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease SCIENCE. 2002 FEB 1; 295 (5556): 865-868	498	498	12	21
27	2792 BRAMBLETT GT, GOEDERT M, JAKES R, MERRICK SE, Trojanowski JQ, et al. ABNORMAL TAU-PHOSPHORYLATION AT SER(396) IN ALZHEIMERS-DISEASE RECAPITULATES DEVELOPMENT AND CONTRIBUTES TO REDUCED MICROTUBULE-BINDING NEURON. 1993 JUN; 10 (6): 1089-1099	493	493	22	51
28	1019 Lee VMY, CARDEN MJ, SCHLAEPFER WW, Trojanowski JQ MONOCLONAL-ANTIBODIES DISTINGUISH SEVERAL DIFFERENTIALLY PHOSPHORYLATED STATES OF THE 2 LARGEST RAT NEUROFILAMENT SUBUNITS (NF-H AND NF-M) AND DEMONSTRATE THEIR EXISTENCE IN THE NORMAL NERVOUS-SYSTEM OF ADULT-RATS JOURNAL OF NEUROSCIENCE. 1987 NOV; 7 (11): 3474-3488	488	488	12	38
29	5233 Paulson HL, Perez MK, Trottier Y, Trojanowski JQ, Subramony SH, et al. Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3 NEURON. 1997 AUG; 19 (2): 333-344	478	478	0	66
30	7995 Conway KA, Lee SJ, Rochet JC, Ding TT, Williamson RE, et al. Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000 JAN 18; 97 (2): 571-576	463	615	21	45
#	Date / Author / Journal	LCS	GCS	LCR	CR
31	6588 Hong M, Zhukareva V, Vogelsberg-Ragaglia V, Wszolek Z, Reed L, et al. Mutation-specific functional impairments in distinct Tau isoforms of hereditary FTDP-17 SCIENCE. 1998 DEC 4; 282 (5395): 1914-1917	454	454	13	21
32	6414 Leroy E, Boyer R, Auburger G, Leube B, Ulm G, et al. The ubiquitin pathway in Parkinson's disease NATURE. 1998 OCT 1; 395 (6701): 451-452	447	844	2	9
33	3624 GAMES D, ADAMS D, ALESSANDRINI R, BARBOUR R, BERTHELETTE P, et al. ALZHEIMER-TYPE NEUROPATHOLOGY IN TRANSGENIC MICE OVEREXPRESSING V717F BETA-AMYLOID PRECURSOR PROTEIN NATURE. 1995 FEB 9; 373 (6514): 523-527	438	1527	2	29
34	1225 KOSIK KS, ORECCHIO LD, BINDER L, Trojanowski JQ, Lee VMY, et al. EPITOPES THAT SPAN THE TAU-MOLECULE ARE SHARED WITH PAIRED HELICAL FILAMENTS NEURON. 1988 NOV; 1 (9): 817-825	433	433	2	52
35	1020 CARDEN MJ, Trojanowski JQ, SCHLAEPFER WW, Lee VMY 2-STAGE EXPRESSION OF NEUROFILAMENT POLYPEPTIDES DURING RAT NEUROGENESIS WITH EARLY ESTABLISHMENT OF ADULT PHOSPHORYLATION PATTERNS JOURNAL OF NEUROSCIENCE. 1987 NOV; 7 (11): 3489-3504	428	427	13	94
36	4421 Parchi P, Castellani R, Capellari S, Ghetti B, Young K, et al. Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease ANNALS OF NEUROLOGY. 1996 JUN; 39 (6): 767-778	425	427	0	58
37	5926 Davidson WS, Jonas A, Clayton DF, George JM Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes JOURNAL OF BIOLOGICAL CHEMISTRY. 1998 APR 17; 273 (16): 9443-9449	424	507	2	42
38	9437 Selkoe DJ Alzheimer's disease: Genes, proteins, and therapy PHYSIOLOGICAL REVIEWS. 2001 APR; 81 (2): 741-766	416	2136	35	216
39	3232 JAKES R, SPILLANTINI MG, GOEDERT M IDENTIFICATION OF 2 DISTINCT SYNUCLEINS FROM HUMAN BRAIN FEBS LETTERS. 1994 MAY 23; 345 (1): 27-32	411	477	7	25
40	3400 MATSUO ES, SHIN RW, BILLINGSLEY ML, VANDEVOORDE A, OCONNOR M, et al. BIOPSY-DERIVED ADULT HUMAN BRAIN TAU IS PHOSPHORYLATED AT MANY OF THE SAME SITES AS ALZHEIMERS-DISEASE PAIRED HELICAL FILAMENT-TAU NEURON. 1994 OCT; 13 (4): 989-1002	407	405	31	50
#	Date / Author / Journal	LCS	GCS	LCR	CR
41	8535 Buee L, Bussiere T, Buee-Scherrer V, Delacourte A, Hof PR Tau protein isoforms, phosphorylation and role in neurodegenerative disorders BRAIN RESEARCH REVIEWS. 2000 AUG; 33 (1): 95-130	400	555	218	429
42	8920 Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, et al. Chronic systemic pesticide exposure reproduces features of Parkinson's disease NATURE NEUROSCIENCE. 2000 DEC; 3 (12): 1301-1306	399	1200	6	41
43	8462 Shimura H, Hattori N, Kubo S, Mizuno Y, Asakawa S, et al. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase NATURE GENETICS. 2000 JUL; 25 (3): 302-305	394	833	10	30
44	12635 Olanow CW, Goetz CG, Kordower JH, Stoessl AJ, Sossi V, et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease ANNALS OF NEUROLOGY. 2003 SEP; 54 (3): 403-414	378	446	4	37
45	4285 Forno LS Neuropathology of Parkinson's disease JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 1996 MAR; 55 (3): 259-272	377	597	9	100
46	4070 RINK A, FUNG KM, Trojanowski JQ, Lee VMY, NEUGEBAUER E, et al. EVIDENCE OF APOPTOTIC CELL-DEATH AFTER EXPERIMENTAL TRAUMATIC BRAIN INJURY IN THE RAT AMERICAN JOURNAL OF PATHOLOGY. 1995 DEC; 147 (6): 1575-1583	373	373	3	29
47	8560 Lewis J, McGowan E, Rockwood J, Melrose H, Nacharaju P, et al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein NATURE GENETICS. 2000 AUG; 25 (4): 402-405	359	444	16	23
48	9695 Shimura H, Schlossmacher MC, Hattori N, Frosch MP, Trockenbacher A, et al. Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease SCIENCE. 2001 JUL 13; 293 (5528): 263-269	356	585	13	37
49	10058 Conway KA, Rochet JC, Bieganski RM, Lansbury PT Kinetic stabilization of the alpha-synuclein protofibril by a dopamine- alpha-synuclein adduct SCIENCE. 2001 NOV 9; 294 (5545): 1346-1349	350	451	17	31
50	6062 Clayton DF, George JM The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease TRENDS IN NEUROSCIENCES. 1998 JUN; 21 (6): 249-254	343	395	3	49
#	Date / Author / Journal	LCS	GCS	LCR	CR
51	2367 DREWES G, LICHTENBERGKRAAG B, DORING F, MANDELKOW EM, BIERNAT J, et al. MITOGEN ACTIVATED PROTEIN (MAP) KINASE TRANSFORMS TAU-PROTEIN INTO AN ALZHEIMER-LIKE STATE EMBO JOURNAL. 1992 JUN; 11 (6): 2131-2138	339	471	8	55
52	10494 Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, et al. alpha-Synuclein is phosphorylated in synucleinopathy lesions NATURE CELL BIOLOGY. 2002 FEB; 4 (2): 160-164	339	369	22	25
53	2797 GOEDERT M, JAKES R, CROWTHER RA, SIX J, LUBKE U, et al. THE ABNORMAL PHOSPHORYLATION OF TAU-PROTEIN AT SER-202 IN ALZHEIMER-DISEASE RECAPITULATES PHOSPHORYLATION DURING DEVELOPMENT PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1993 JUN 1; 90 (11): 5066-5070	337	337	22	38
54	6276 Tu PH, Galvin JE, Baba M, Giasson B, Tomita T, et al. Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein ANNALS OF NEUROLOGY. 1998 SEP; 44 (3): 415-422	334	334	16	43
55	11892 Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, et al. Mutations in the DJ-1 gene associated with autosomal recessive early- onset parkinsonism SCIENCE. 2003 JAN 10; 299 (5604): 256-259	334	773	4	20
56	13512 Klunk WE, Engler H, Nordberg A, Wang YM, Blomqvist G, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B ANNALS OF NEUROLOGY. 2004 MAR; 55 (3): 306-319	326	796	13	52
57	7027 Narhi L, Wood SJ, Steavenson S, Jiang YJ, Wu GM, et al. Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation JOURNAL OF BIOLOGICAL CHEMISTRY. 1999 APR 2; 274 (14): 9843-9846	323	349	7	16
58	9666 Goedert M Alpha-synuclein and neurodegenerative diseases NATURE REVIEWS NEUROSCIENCE. 2001 JUL; 2 (7): 492-501	320	395	69	129
59	2215 GREENBERG SG, DAVIES P, SCHEIN JD, BINDER LI HYDROFLUORIC ACID-TREATED TAU-PHF PROTEINS DISPLAY THE SAME BIOCHEMICAL-PROPERTIES AS NORMAL TAU JOURNAL OF BIOLOGICAL CHEMISTRY. 1992 JAN 5; 267 (1): 564-569	319	391	5	46
60	17542 Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, et al. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17 NATURE. 2006 AUG 24; 442 (7105): 916-919	319	389	15	31
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61	18109 Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, et al. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006 DEC 22; 351 (3): 602-611	313	318	22	54
62	2829 BIERNAT J, GUSTKE N, DREWES G, MANDELKOW EM, MANDELKOW E PHOSPHORYLATION OF SER(262) STRONGLY REDUCES BINDING OF TAU-PROTEIN TO MICROTUBULES - DISTINCTION BETWEEN PHF-LIKE IMMUNOREACTIVITY AND MICROTUBULE-BINDING NEURON. 1993 JUL; 11 (1): 153-163	311	383	24	52
63	3588 MORISHIMAKAWASHIMA M, HASEGAWA M, TAKIO K, SUZUKI M, YOSHIDA H, et al. PROLINE-DIRECTED AND NON-PROLINE-DIRECTED PHOSPHORYLATION OF PHF-TAU JOURNAL OF BIOLOGICAL CHEMISTRY. 1995 JAN 13; 270 (2): 823-829	310	362	41	72
64	6232 Conti AC, Raghupathi R, Trojanowski JQ, McIntosh TK Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period JOURNAL OF NEUROSCIENCE. 1998 AUG 1; 18 (15): 5663-5672	309	309	14	70
65	6991 Baker M, Litvan I, Houlden H, Adamson J, Dickson D, et al. Association of an extended haplotype in the tau gene with progressive supranuclear palsy HUMAN MOLECULAR GENETICS. 1999 APR; 8 (4): 711-715	309	368	14	19
66	9799 Gotz J, Chen F, van Dorpe J, Nitsch RM Formation of neurofibrillary tangles in P301L tau transgenic mice induced by A beta 42 fibrils SCIENCE. 2001 AUG 24; 293 (5534): 1491-1495	307	484	17	32
67	2282 TOHYAMA T, Lee VMY, RORKE LB, MARVIN M, MCKAY RDG, et al. NESTIN EXPRESSION IN EMBRYONIC HUMAN NEUROEPITHELIUM AND IN HUMAN NEUROEPITHELIAL TUMOR-CELLS LABORATORY INVESTIGATION. 1992 MAR; 66 (3): 303-313	305	305	24	49
68	10828 Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, et al. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein NEURON. 2002 MAY 16; 34 (4): 521-533	304	304	34	49
69	4646 Goedert M, Jakes R, Spillantini MG, Hasegawa M, Smith MJ, et al. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans NATURE. 1996 OCT 10; 383 (6600): 550-553	300	428	22	33
70	8299 Murphy DD, Rueter SM, Trojanowski JQ, Lee VMY Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons JOURNAL OF NEUROSCIENCE. 2000 MAY 1; 20 (9): 3214-3220	299	299	16	38
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71	2330 HARDY JA, HIGGINS GA ALZHEIMERS-DISEASE - THE AMYLOID CASCADE HYPOTHESIS SCIENCE. 1992 APR 10; 256 (5054): 184-185	296	1045	6	64
72	6179 Spillantini MG, Crowther RA, Jakes R, Cairns NJ, Lantos PL, et al. Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies NEUROSCIENCE LETTERS. 1998 JUL 31; 251 (3): 205-208	296	321	7	17
73	12509 Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular A beta and synaptic dysfunction NEURON. 2003 JUL 31; 39 (3): 409-421	296	762	16	48
74	1786 GOEDERT M, JAKES R EXPRESSION OF SEPARATE ISOFORMS OF HUMAN TAU-PROTEIN - CORRELATION WITH THE TAU-PATTERN IN BRAIN AND EFFECTS ON TUBULIN POLYMERIZATION EMBO JOURNAL. 1990 DEC; 9 (13): 4225-4230	285	380	4	44
75	7615 Ishihara T, Hong M, Zhang B, Nakagawa Y, Lee MK, et al. Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform NEURON. 1999 NOV; 24 (3): 751-762	283	283	33	47
76	3235 BRAAK E, BRAAK H, MANDELKOW EM A SEQUENCE OF CYTOSKELETON CHANGES RELATED TO THE FORMATION OF NEUROFIBRILLARY TANGLES AND NEUROPIL THREADS ACTA NEUROPATHOLOGICA. 1994 JUN; 87 (6): 554-567	278	413	23	63
77	4866 Conrad C, Andreadis A, Trojanowski JQ, Dickson DW, Kang D, et al. Genetic evidence for the involvement of tau in progressive supranuclear palsy ANNALS OF NEUROLOGY. 1997 FEB; 41 (2): 277-281	278	278	8	24
78	2307 BIERNAT J, MANDELKOW EM, SCHROTER C, LICHTENBERGKRAAG B, STEINER B, et al. THE SWITCH OF TAU-PROTEIN TO AN ALZHEIMER-LIKE STATE INCLUDES THE PHOSPHORYLATION OF 2 SERINE PROLINE MOTIFS UPSTREAM OF THE MICROTUBULE BINDING REGION EMBO JOURNAL. 1992 APR; 11 (4): 1593-1597	275	342	8	23
79	5363 Hyman BT, Trojanowski JQ Editorial on consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute working group on diagnostic criteria for the neuropathological assessment of Alzheimer disease JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 1997 OCT; 56 (10): 1095-1097	275	275	0	9
80	6960 Giasson BI, Uryu K, Trojanowski JQ, Lee VMY Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro JOURNAL OF BIOLOGICAL CHEMISTRY. 1999 MAR 19; 274 (12): 7619-7622	274	274	22	43
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81	14581 Zimprich A, Biskup S, Leitner P, Lichtner P, Farrer M, et al. Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology NEURON. 2004 NOV 18; 44 (4): 601-607	274	667	15	31
82	6409 Spillantini MG, Goedert M Tau protein pathology in neurodegenerative diseases TRENDS IN NEUROSCIENCES. 1998 OCT; 21 (10): 428-433	270	360	41	66
83	15706 SantaCruz K, Lewis J, Spires T, Paulson J, Kotilinek L, et al. Tau suppression in a neurodegenerative mouse model improves memory function SCIENCE. 2005 JUL 15; 309 (5733): 476-481	270	363	13	27
84	6442 Clark LN, Poorkaj P, Wszolek Z, Geschwind DH, Nasreddine ZS, et al. Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998 OCT 27; 95 (22): 13103-13107	266	266	12	23
85	17543 Cruts M, Gijselinck I, van der Zee J, Engelborghs S, Wils H, et al. Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21 NATURE. 2006 AUG 24; 442 (7105): 920-924	266	322	11	28
86	20727 Sreedharan J, Blair IP, Tripathi VB, Hu X, Vance C, et al. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis SCIENCE. 2008 MAR 21; 319 (5870): 1668-1672	260	306	15	26
87	5703 Takeda A, Mallory M, Sundsmo M, Honer W, Hansen L, et al. Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders AMERICAN JOURNAL OF PATHOLOGY. 1998 FEB; 152 (2): 367-372	259	278	10	34
88	8147 Conway KA, Harper JD, Lansbury PT Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid BIOCHEMISTRY. 2000 MAR 14; 39 (10): 2552-2563	257	350	30	82
89	8586 van der Putten H, Wiederhold KH, Probst A, Barbieri S, Mistl C, et al. Neuropathology in mice expressing human alpha-synuclein JOURNAL OF NEUROSCIENCE. 2000 AUG 15; 20 (16): 6021-6029	256	275	37	58
90	6429 Jensen PH, Nielsen MS, Jakes R, Dotti G, Goedert M Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation JOURNAL OF BIOLOGICAL CHEMISTRY. 1998 OCT 9; 273 (41): 26292-26294	255	270	8	21
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91	9224 Giasson BI, Murray IVJ, Trojanowski JQ, Lee VMY A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly JOURNAL OF BIOLOGICAL CHEMISTRY. 2001 JAN 26; 276 (4): 2380-2386	254	254	30	36
92	2743 XU ZS, CORK LC, GRIFFIN JW, CLEVELAND DW INCREASED EXPRESSION OF NEUROFILAMENT SUBUNIT-NF-L PRODUCES MORPHOLOGICAL ALTERATIONS THAT RESEMBLE THE PATHOLOGY OF HUMAN MOTOR- NEURON DISEASE CELL. 1993 APR 9; 73 (1): 23-33	252	422	3	36
93	6439 Hasegawa M, Smith MJ, Goedert M Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly FEBS LETTERS. 1998 OCT 23; 437 (3): 207-210	252	259	18	26
94	6452 Lippa CF, Fujiwara H, Mann DMA, Giasson B, Baba M, et al. Lewy bodies contain altered alpha-synuclein in brains of many familiar Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes AMERICAN JOURNAL OF PATHOLOGY. 1998 NOV; 153 (5): 1365-1370	251	251	8	33
95	2744 COTE F, COLLARD JF, JULIEN JP PROGRESSIVE NEURONOPATHY IN TRANSGENIC MICE EXPRESSING THE HUMAN NEUROFILAMENT HEAVY GENE - A MOUSE MODEL OF AMYOTROPHIC-LATERAL- SCLEROSIS CELL. 1993 APR 9; 73 (1): 35-46	248	431	10	69
96	2953 GOEDERT M TAU-PROTEIN AND THE NEUROFIBRILLARY PATHOLOGY OF ALZHEIMERS-DISEASE TRENDS IN NEUROSCIENCES. 1993 NOV; 16 (11): 460-465	247	397	33	64
97	6416 Klement IA, Skinner PJ, Kaytor MD, Yi H, Hersch SM, et al. Ataxin-1 nuclear localization and aggregation: Role in polyglutamine- induced disease in SCA1 transgenic mice CELL. 1998 OCT 2; 95 (1): 41-53	245	590	7	49
98	7289 Wood SJ, Wypych J, Steavenson S, Louis JC, Citron M, et al. alpha-synuclein fibrillogenesis is nucleation-dependent - Implications for the pathogenesis of Parkinson's disease JOURNAL OF BIOLOGICAL CHEMISTRY. 1999 JUL 9; 274 (28): 19509-19512	245	290	13	27
99	7110 D'Souza I, Poorkaj P, Hong M, Nochlin D, Lee VMY, et al. Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999 MAY 11; 96 (10): 5598-5603	243	286	14	39
100	12702 Dauer W, Przedborski S Parkinson's disease: Mechanisms and models NEURON. 2003 SEP 11; 39 (6): 889-909	243	861	66	235

Date / Author / Journal

LCS

GCS

LCR

5270 Spillantini MG, Schmidt ML, Lee VMY, Trojanowski JQ, Jakes R, et al.

alpha-synuclein in Lewy bodies

NATURE. 1997 AUG 28; 388 (6645): 839-840

1896

6083 Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, et al.

Association of missense and 5 '-splice-site mutations in tau with the inherited dementia FTDP-17

NATURE. 1998 JUN 18; 393 (6686): 702-705

1368

1369

5735 Kruger R, Kuhn W, Muller T, Woitalla D, Graeber M, et al.

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

NATURE GENETICS. 1998 FEB; 18 (2): 106-108

1324

1597

1893 Lee VMY, BALIN BJ, OTVOS L, Trojanowski JQ

A68 - A MAJOR SUBUNIT OF PAIRED HELICAL FILAMENTS AND DERIVATIZED FORMS OF NORMAL-TAU

SCIENCE. 1991 FEB 8; 251 (4994): 675-678

1000

9363 Freed CR, Greene PE, Breeze RE, Tsai WY, DuMouchel W, et al.

Transplantation of embryonic dopamine neurons for severe Parkinson's disease.

NEW ENGLAND JOURNAL OF MEDICINE. 2001 MAR 8; 344 (10): 710-719

902

6569 Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, et al.

Frontotemporal lobar degeneration - A consensus on clinical diagnostic criteria

NEUROLOGY. 1998 DEC; 51 (6): 1546-1554

818

1661

8982 Lee VMY, Goedert M, Trojanowski JQ

Neurodegenerative tauopathies

ANNUAL REVIEW OF NEUROSCIENCE. 2001; 24: 1121-1159

807

178

256

1444 GOEDERT M, SPILLANTINI MG, JAKES R, RUTHERFORD D, CROWTHER RA

MULTIPLE ISOFORMS OF HUMAN MICROTUBULE-ASSOCIATED PROTEIN-TAU - SEQUENCES AND LOCALIZATION IN NEUROFIBRILLARY TANGLES OF ALZHEIMERS- DISEASE

NEURON. 1989 OCT; 3 (4): 519-526

785

998

12876 Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, et al.

alpha-synuclein locus triplication causes Parkinson's disease

SCIENCE. 2003 OCT 31; 302 (5646): 841-841

754

1059

6009 Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M

alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998 MAY 26; 95 (11): 6469-6473

733

859

Date / Author / Journal

LCS

GCS

LCR

6089 Spillantini MG, Murrell JR, Goedert M, Farlow MR, Klug A, et al.

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998 JUN 23; 95 (13): 7737-7741

728

752

8074 Masliah E, Rockenstein E, Veinbergs I, Mallory M, Hashimoto M, et al.

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: Implications for neurodegenerative disorders

SCIENCE. 2000 FEB 18; 287 (5456): 1265-1269

706

838

16370 McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, et al.

Diagnosis and management of dementia with Lewy bodies - Third report of the DLB consortium

NEUROLOGY. 2005 DEC 27; 65 (12): 1863-1872

706

105

5911 Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, et al.

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

NATURE. 1998 APR 9; 392 (6676): 605-608

703

1743

5856 Baba M, Nakajo S, Tu PH, Tomita T, Nakaya K, et al.

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with lewy bodies

AMERICAN JOURNAL OF PATHOLOGY. 1998 APR; 152 (4): 879-884

667

6021 Poorkaj P, Bird TD, Wijsman E, Nemens E, Garruto RM, et al.

Tau is a candidate gene for chromosome 17 frontotemporal dementia

ANNALS OF NEUROLOGY. 1998 JUN; 43 (6): 815-825

663

698

8165 Feany MB, Bender WW

A Drosophila model of Parkinson's disease

NATURE. 2000 MAR 23; 404 (6776): 394-398

644

835

8855 Giasson BI, Duda JE, Murray IVJ, Chen QP, Souza JM, et al.

Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions

SCIENCE. 2000 NOV 3; 290 (5493): 985-989

638

17811 Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, et al.

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

SCIENCE. 2006 OCT 6; 314 (5796): 130-133

631

11057 Hardy J, Selkoe DJ

Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics

SCIENCE. 2002 JUL 19; 297 (5580): 353-356

623

2710

Date / Author / Journal

LCS

GCS

LCR

9991 McKhann GM, Albert MS, Grossman M, Miller B, Dickson D, et al.

Clinical and pathological diagnosis of Frontotemporal Dementia - Report of the work group on Frontotemporal Dementia and Pick's disease

ARCHIVES OF NEUROLOGY. 2001 NOV; 58 (11): 1803-1809

598

599

13393 Zarranz JJ, Alegre J, Gomez-Esteban JC, Lezcano E, Ros R, et al.

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

ANNALS OF NEUROLOGY. 2004 FEB; 55 (2): 164-173

555

646

6485 Conway KA, Harper JD, Lansbury PT

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

NATURE MEDICINE. 1998 NOV; 4 (11): 1318-1320

533

621

12066 Braak H, Del Tredici K, Rub U, de Vos RAI, Steur ENHJ, et al.

Staging of brain pathology related to sporadic Parkinson's disease

NEUROBIOLOGY OF AGING. 2003 MAR-APR; 24 (2): 197-211

515

1133

2210 GOEDERT M, SPILLANTINI MG, CAIRNS NJ, CROWTHER RA

TAU-PROTEINS OF ALZHEIMER PAIRED HELICAL FILAMENTS - ABNORMAL PHOSPHORYLATION OF ALL 6 BRAIN ISOFORMS

NEURON. 1992 JAN; 8 (1): 159-168

508

603

10518 Auluck PK, Chan HYE, Trojanowski JQ, Lee VMY, Bonini NM

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

SCIENCE. 2002 FEB 1; 295 (5556): 865-868

498

2792 BRAMBLETT GT, GOEDERT M, JAKES R, MERRICK SE, Trojanowski JQ, et al.

ABNORMAL TAU-PHOSPHORYLATION AT SER(396) IN ALZHEIMERS-DISEASE RECAPITULATES DEVELOPMENT AND CONTRIBUTES TO REDUCED MICROTUBULE-BINDING

NEURON. 1993 JUN; 10 (6): 1089-1099

493

1019 Lee VMY, CARDEN MJ, SCHLAEPFER WW, Trojanowski JQ

MONOCLONAL-ANTIBODIES DISTINGUISH SEVERAL DIFFERENTIALLY PHOSPHORYLATED STATES OF THE 2 LARGEST RAT NEUROFILAMENT SUBUNITS (NF-H AND NF-M) AND DEMONSTRATE THEIR EXISTENCE IN THE NORMAL NERVOUS-SYSTEM OF ADULT-RATS

JOURNAL OF NEUROSCIENCE. 1987 NOV; 7 (11): 3474-3488

488

5233 Paulson HL, Perez MK, Trottier Y, Trojanowski JQ, Subramony SH, et al.

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3

NEURON. 1997 AUG; 19 (2): 333-344

478

7995 Conway KA, Lee SJ, Rochet JC, Ding TT, Williamson RE, et al.

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000 JAN 18; 97 (2): 571-576

463

615

Date / Author / Journal

LCS

GCS

LCR

6588 Hong M, Zhukareva V, Vogelsberg-Ragaglia V, Wszolek Z, Reed L, et al.

Mutation-specific functional impairments in distinct Tau isoforms of hereditary FTDP-17

SCIENCE. 1998 DEC 4; 282 (5395): 1914-1917

454

6414 Leroy E, Boyer R, Auburger G, Leube B, Ulm G, et al.

The ubiquitin pathway in Parkinson's disease

NATURE. 1998 OCT 1; 395 (6701): 451-452

447

844

3624 GAMES D, ADAMS D, ALESSANDRINI R, BARBOUR R, BERTHELETTE P, et al.

ALZHEIMER-TYPE NEUROPATHOLOGY IN TRANSGENIC MICE OVEREXPRESSING V717F BETA-AMYLOID PRECURSOR PROTEIN

NATURE. 1995 FEB 9; 373 (6514): 523-527

438

1527

1225 KOSIK KS, ORECCHIO LD, BINDER L, Trojanowski JQ, Lee VMY, et al.

EPITOPES THAT SPAN THE TAU-MOLECULE ARE SHARED WITH PAIRED HELICAL FILAMENTS

NEURON. 1988 NOV; 1 (9): 817-825

433

1020 CARDEN MJ, Trojanowski JQ, SCHLAEPFER WW, Lee VMY

2-STAGE EXPRESSION OF NEUROFILAMENT POLYPEPTIDES DURING RAT NEUROGENESIS WITH EARLY ESTABLISHMENT OF ADULT PHOSPHORYLATION PATTERNS

JOURNAL OF NEUROSCIENCE. 1987 NOV; 7 (11): 3489-3504

428

427

4421 Parchi P, Castellani R, Capellari S, Ghetti B, Young K, et al.

Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease

ANNALS OF NEUROLOGY. 1996 JUN; 39 (6): 767-778

425

427

5926 Davidson WS, Jonas A, Clayton DF, George JM

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

JOURNAL OF BIOLOGICAL CHEMISTRY. 1998 APR 17; 273 (16): 9443-9449

424

507

9437 Selkoe DJ

Alzheimer's disease: Genes, proteins, and therapy

PHYSIOLOGICAL REVIEWS. 2001 APR; 81 (2): 741-766

416

2136

216

3232 JAKES R, SPILLANTINI MG, GOEDERT M

IDENTIFICATION OF 2 DISTINCT SYNUCLEINS FROM HUMAN BRAIN

FEBS LETTERS. 1994 MAY 23; 345 (1): 27-32

411

477

3400 MATSUO ES, SHIN RW, BILLINGSLEY ML, VANDEVOORDE A, OCONNOR M, et al.

BIOPSY-DERIVED ADULT HUMAN BRAIN TAU IS PHOSPHORYLATED AT MANY OF THE SAME SITES AS ALZHEIMERS-DISEASE PAIRED HELICAL FILAMENT-TAU

NEURON. 1994 OCT; 13 (4): 989-1002

407

405

Date / Author / Journal

LCS

GCS

LCR

8535 Buee L, Bussiere T, Buee-Scherrer V, Delacourte A, Hof PR

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders

BRAIN RESEARCH REVIEWS. 2000 AUG; 33 (1): 95-130

400

555

218

429

8920 Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, et al.

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

NATURE NEUROSCIENCE. 2000 DEC; 3 (12): 1301-1306

399

1200

8462 Shimura H, Hattori N, Kubo S, Mizuno Y, Asakawa S, et al.

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

NATURE GENETICS. 2000 JUL; 25 (3): 302-305

394

833

12635 Olanow CW, Goetz CG, Kordower JH, Stoessl AJ, Sossi V, et al.

A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

ANNALS OF NEUROLOGY. 2003 SEP; 54 (3): 403-414

378

446

4285 Forno LS

Neuropathology of Parkinson's disease

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 1996 MAR; 55 (3): 259-272

377

597

100

4070 RINK A, FUNG KM, Trojanowski JQ, Lee VMY, NEUGEBAUER E, et al.

EVIDENCE OF APOPTOTIC CELL-DEATH AFTER EXPERIMENTAL TRAUMATIC BRAIN INJURY IN THE RAT

AMERICAN JOURNAL OF PATHOLOGY. 1995 DEC; 147 (6): 1575-1583

373

8560 Lewis J, McGowan E, Rockwood J, Melrose H, Nacharaju P, et al.

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

NATURE GENETICS. 2000 AUG; 25 (4): 402-405

359

444

9695 Shimura H, Schlossmacher MC, Hattori N, Frosch MP, Trockenbacher A, et al.

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease

SCIENCE. 2001 JUL 13; 293 (5528): 263-269

356

585

10058 Conway KA, Rochet JC, Bieganski RM, Lansbury PT

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine- alpha-synuclein adduct

SCIENCE. 2001 NOV 9; 294 (5545): 1346-1349

350

451

6062 Clayton DF, George JM

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

TRENDS IN NEUROSCIENCES. 1998 JUN; 21 (6): 249-254

343

395

Date / Author / Journal

LCS

GCS

LCR

2367 DREWES G, LICHTENBERGKRAAG B, DORING F, MANDELKOW EM, BIERNAT J, et al.

MITOGEN ACTIVATED PROTEIN (MAP) KINASE TRANSFORMS TAU-PROTEIN INTO AN ALZHEIMER-LIKE STATE

EMBO JOURNAL. 1992 JUN; 11 (6): 2131-2138

339

471

10494 Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, et al.

alpha-Synuclein is phosphorylated in synucleinopathy lesions

NATURE CELL BIOLOGY. 2002 FEB; 4 (2): 160-164

339

369

2797 GOEDERT M, JAKES R, CROWTHER RA, SIX J, LUBKE U, et al.

THE ABNORMAL PHOSPHORYLATION OF TAU-PROTEIN AT SER-202 IN ALZHEIMER-DISEASE RECAPITULATES PHOSPHORYLATION DURING DEVELOPMENT

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1993 JUN 1; 90 (11): 5066-5070

337

6276 Tu PH, Galvin JE, Baba M, Giasson B, Tomita T, et al.

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein

ANNALS OF NEUROLOGY. 1998 SEP; 44 (3): 415-422

334

11892 Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, et al.

Mutations in the DJ-1 gene associated with autosomal recessive early- onset parkinsonism

SCIENCE. 2003 JAN 10; 299 (5604): 256-259

334

773

13512 Klunk WE, Engler H, Nordberg A, Wang YM, Blomqvist G, et al.

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

ANNALS OF NEUROLOGY. 2004 MAR; 55 (3): 306-319

326

796

7027 Narhi L, Wood SJ, Steavenson S, Jiang YJ, Wu GM, et al.

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

JOURNAL OF BIOLOGICAL CHEMISTRY. 1999 APR 2; 274 (14): 9843-9846

323

349

9666 Goedert M

Alpha-synuclein and neurodegenerative diseases

NATURE REVIEWS NEUROSCIENCE. 2001 JUL; 2 (7): 492-501

320

395

129

2215 GREENBERG SG, DAVIES P, SCHEIN JD, BINDER LI

HYDROFLUORIC ACID-TREATED TAU-PHF PROTEINS DISPLAY THE SAME BIOCHEMICAL-PROPERTIES AS NORMAL TAU

JOURNAL OF BIOLOGICAL CHEMISTRY. 1992 JAN 5; 267 (1): 564-569

319

391

17542 Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, et al.

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

NATURE. 2006 AUG 24; 442 (7105): 916-919

319

389

Date / Author / Journal

LCS

GCS

LCR

18109 Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, et al.

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006 DEC 22; 351 (3): 602-611

313

318

2829 BIERNAT J, GUSTKE N, DREWES G, MANDELKOW EM, MANDELKOW E

PHOSPHORYLATION OF SER(262) STRONGLY REDUCES BINDING OF TAU-PROTEIN TO MICROTUBULES - DISTINCTION BETWEEN PHF-LIKE IMMUNOREACTIVITY AND MICROTUBULE-BINDING

NEURON. 1993 JUL; 11 (1): 153-163

311

383

3588 MORISHIMAKAWASHIMA M, HASEGAWA M, TAKIO K, SUZUKI M, YOSHIDA H, et al.

PROLINE-DIRECTED AND NON-PROLINE-DIRECTED PHOSPHORYLATION OF PHF-TAU

JOURNAL OF BIOLOGICAL CHEMISTRY. 1995 JAN 13; 270 (2): 823-829

310

362

6232 Conti AC, Raghupathi R, Trojanowski JQ, McIntosh TK

Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period

JOURNAL OF NEUROSCIENCE. 1998 AUG 1; 18 (15): 5663-5672

309

6991 Baker M, Litvan I, Houlden H, Adamson J, Dickson D, et al.

Association of an extended haplotype in the tau gene with progressive supranuclear palsy

HUMAN MOLECULAR GENETICS. 1999 APR; 8 (4): 711-715

309

368

9799 Gotz J, Chen F, van Dorpe J, Nitsch RM

Formation of neurofibrillary tangles in P301L tau transgenic mice induced by A beta 42 fibrils

SCIENCE. 2001 AUG 24; 293 (5534): 1491-1495

307

484

2282 TOHYAMA T, Lee VMY, RORKE LB, MARVIN M, MCKAY RDG, et al.

NESTIN EXPRESSION IN EMBRYONIC HUMAN NEUROEPITHELIUM AND IN HUMAN NEUROEPITHELIAL TUMOR-CELLS

LABORATORY INVESTIGATION. 1992 MAR; 66 (3): 303-313

305

10828 Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, et al.

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein

NEURON. 2002 MAY 16; 34 (4): 521-533

304

4646 Goedert M, Jakes R, Spillantini MG, Hasegawa M, Smith MJ, et al.

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

NATURE. 1996 OCT 10; 383 (6600): 550-553

300

428

8299 Murphy DD, Rueter SM, Trojanowski JQ, Lee VMY

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

JOURNAL OF NEUROSCIENCE. 2000 MAY 1; 20 (9): 3214-3220

299

Date / Author / Journal

LCS

GCS

LCR

2330 HARDY JA, HIGGINS GA

ALZHEIMERS-DISEASE - THE AMYLOID CASCADE HYPOTHESIS

SCIENCE. 1992 APR 10; 256 (5054): 184-185

296

1045

6179 Spillantini MG, Crowther RA, Jakes R, Cairns NJ, Lantos PL, et al.

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

NEUROSCIENCE LETTERS. 1998 JUL 31; 251 (3): 205-208

296

321

12509 Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, et al.

Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular A beta and synaptic dysfunction

NEURON. 2003 JUL 31; 39 (3): 409-421

296

762

1786 GOEDERT M, JAKES R

EXPRESSION OF SEPARATE ISOFORMS OF HUMAN TAU-PROTEIN - CORRELATION WITH THE TAU-PATTERN IN BRAIN AND EFFECTS ON TUBULIN POLYMERIZATION

EMBO JOURNAL. 1990 DEC; 9 (13): 4225-4230

285

380

7615 Ishihara T, Hong M, Zhang B, Nakagawa Y, Lee MK, et al.

Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform

NEURON. 1999 NOV; 24 (3): 751-762

283

3235 BRAAK E, BRAAK H, MANDELKOW EM

A SEQUENCE OF CYTOSKELETON CHANGES RELATED TO THE FORMATION OF NEUROFIBRILLARY TANGLES AND NEUROPIL THREADS

ACTA NEUROPATHOLOGICA. 1994 JUN; 87 (6): 554-567

278

413

4866 Conrad C, Andreadis A, Trojanowski JQ, Dickson DW, Kang D, et al.

Genetic evidence for the involvement of tau in progressive supranuclear palsy

ANNALS OF NEUROLOGY. 1997 FEB; 41 (2): 277-281

278

2307 BIERNAT J, MANDELKOW EM, SCHROTER C, LICHTENBERGKRAAG B, STEINER B, et al.

THE SWITCH OF TAU-PROTEIN TO AN ALZHEIMER-LIKE STATE INCLUDES THE PHOSPHORYLATION OF 2 SERINE PROLINE MOTIFS UPSTREAM OF THE MICROTUBULE BINDING REGION

EMBO JOURNAL. 1992 APR; 11 (4): 1593-1597

275

342

5363 Hyman BT, Trojanowski JQ

Editorial on consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute working group on diagnostic criteria for the neuropathological assessment of Alzheimer disease

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 1997 OCT; 56 (10): 1095-1097

275

6960 Giasson BI, Uryu K, Trojanowski JQ, Lee VMY

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

JOURNAL OF BIOLOGICAL CHEMISTRY. 1999 MAR 19; 274 (12): 7619-7622

274

Date / Author / Journal

LCS

GCS

LCR

14581 Zimprich A, Biskup S, Leitner P, Lichtner P, Farrer M, et al.

Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology

NEURON. 2004 NOV 18; 44 (4): 601-607

274

667

6409 Spillantini MG, Goedert M

Tau protein pathology in neurodegenerative diseases

TRENDS IN NEUROSCIENCES. 1998 OCT; 21 (10): 428-433

270

360

15706 SantaCruz K, Lewis J, Spires T, Paulson J, Kotilinek L, et al.

Tau suppression in a neurodegenerative mouse model improves memory function

SCIENCE. 2005 JUL 15; 309 (5733): 476-481

270

363

6442 Clark LN, Poorkaj P, Wszolek Z, Geschwind DH, Nasreddine ZS, et al.

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998 OCT 27; 95 (22): 13103-13107

266

17543 Cruts M, Gijselinck I, van der Zee J, Engelborghs S, Wils H, et al.

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

NATURE. 2006 AUG 24; 442 (7105): 920-924

266

322

20727 Sreedharan J, Blair IP, Tripathi VB, Hu X, Vance C, et al.

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

SCIENCE. 2008 MAR 21; 319 (5870): 1668-1672

260

306

5703 Takeda A, Mallory M, Sundsmo M, Honer W, Hansen L, et al.

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

AMERICAN JOURNAL OF PATHOLOGY. 1998 FEB; 152 (2): 367-372

259

278

8147 Conway KA, Harper JD, Lansbury PT

Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

BIOCHEMISTRY. 2000 MAR 14; 39 (10): 2552-2563

257

350

8586 van der Putten H, Wiederhold KH, Probst A, Barbieri S, Mistl C, et al.

Neuropathology in mice expressing human alpha-synuclein

JOURNAL OF NEUROSCIENCE. 2000 AUG 15; 20 (16): 6021-6029

256

275

6429 Jensen PH, Nielsen MS, Jakes R, Dotti G, Goedert M

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation

JOURNAL OF BIOLOGICAL CHEMISTRY. 1998 OCT 9; 273 (41): 26292-26294

255

270

Date / Author / Journal

LCS

GCS

LCR

9224 Giasson BI, Murray IVJ, Trojanowski JQ, Lee VMY

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly

JOURNAL OF BIOLOGICAL CHEMISTRY. 2001 JAN 26; 276 (4): 2380-2386

254

2743 XU ZS, CORK LC, GRIFFIN JW, CLEVELAND DW

INCREASED EXPRESSION OF NEUROFILAMENT SUBUNIT-NF-L PRODUCES MORPHOLOGICAL ALTERATIONS THAT RESEMBLE THE PATHOLOGY OF HUMAN MOTOR- NEURON DISEASE

CELL. 1993 APR 9; 73 (1): 23-33

252

422

6439 Hasegawa M, Smith MJ, Goedert M

Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly

FEBS LETTERS. 1998 OCT 23; 437 (3): 207-210

252

259

6452 Lippa CF, Fujiwara H, Mann DMA, Giasson B, Baba M, et al.

Lewy bodies contain altered alpha-synuclein in brains of many familiar Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes

AMERICAN JOURNAL OF PATHOLOGY. 1998 NOV; 153 (5): 1365-1370

251

2744 COTE F, COLLARD JF, JULIEN JP

PROGRESSIVE NEURONOPATHY IN TRANSGENIC MICE EXPRESSING THE HUMAN NEUROFILAMENT HEAVY GENE - A MOUSE MODEL OF AMYOTROPHIC-LATERAL- SCLEROSIS

CELL. 1993 APR 9; 73 (1): 35-46

248

431

2953 GOEDERT M

TAU-PROTEIN AND THE NEUROFIBRILLARY PATHOLOGY OF ALZHEIMERS-DISEASE

TRENDS IN NEUROSCIENCES. 1993 NOV; 16 (11): 460-465

247

397

6416 Klement IA, Skinner PJ, Kaytor MD, Yi H, Hersch SM, et al.

Ataxin-1 nuclear localization and aggregation: Role in polyglutamine- induced disease in SCA1 transgenic mice

CELL. 1998 OCT 2; 95 (1): 41-53

245

590

7289 Wood SJ, Wypych J, Steavenson S, Louis JC, Citron M, et al.

alpha-synuclein fibrillogenesis is nucleation-dependent - Implications for the pathogenesis of Parkinson's disease

JOURNAL OF BIOLOGICAL CHEMISTRY. 1999 JUL 9; 274 (28): 19509-19512

245

290

7110 D'Souza I, Poorkaj P, Hong M, Nochlin D, Lee VMY, et al.

Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999 MAY 11; 96 (10): 5598-5603

243

286

100

12702 Dauer W, Przedborski S

Parkinson's disease: Mechanisms and models

NEURON. 2003 SEP 11; 39 (6): 889-909

243

861

235

Trojanowski w/citing papers Publications by JQ Trojanowski and the papers citing JQ Trojanowski	Historiographs	Glossary HistCite Guide About Grand Totals: LCS 336329, GCS 1007154, CR 1762209 Collection span: 1973 - 2011
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