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MELLIN GW, 1962, NEW ENGL J MED, V267, P1184 MELLIN GW, 1962, NEW ENGL J MED, V267, P1238 LENZ W, 1961, DEUT MED WOCHENSCHR, V86, P2555 LENZ W, 1962, DEUT MED WOCHENSCHR, V87, P1232 KUNZ W, 1956, ARZNEIMITTEL-FORSCH, V6, P426 SHESKIN J, 1965, LEPROSY REV, V36, P183 WIEDEMANN HR, 1961, MED WELT, V37, P1863 BECKMANN R, 1962, ARZNEIMITTEL-FORSCH, V12, P1095 |
Nodes: 2685,
Authors: 6203,
Journals: 662,
Outer References: 16023,
Words: 3995
Collection span: 1956 - 2004
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# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
---|---|---|---|---|---|
1201 | 7 | 23 | 1174 1995 SEP [15] BIOLOGICAL & PHARMACEUTICAL BULLETIN 18(9):1228-1233 SASAKI K; SHIBATA Y; HASHIMOTO Y; IWASAKI S BENZYLPHTHALIMIDES AND PHENETHYLPHTHALIMIDES WITH THALIDOMIDE-LIKE ACTIVITY ON THE PRODUCTION OF TUMOR-NECROSIS-FACTOR-ALPHA | 7 | 18 |
1202 | 0 | 0 | 1203 1995 SEP [15] JOURNAL OF INVESTIGATIVE DERMATOLOGY 105(3):479-479 CHARUE D; CHAUVIN E; DUGUET C; REVUZ J; BAGOT M THALIDOMIDE DECREASES THE PRODUCTION OF GM-CSF AND TNF-ALPHA IN MIXED EPIDERMAL-CELL LYMPHOCYTE-REACTION | 2 | 2 |
1203 | 4 | 28 | 1177 1995 OCT [15] BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH 28(10):1069-1076 AARESTRUP FM; GONCALVESDACOSTA SC; SARNO EN THE EFFECT OF THALIDOMIDE ON BCG-INDUCED GRANULOMAS IN MICE | 2 | 9 |
1204 | 0 | 0 | 1180 1995 OCT [15] CHEMISTRY IN BRITAIN 31(10):760-760 [Anon] THALIDOMIDE REVIVAL | 0 | 0 |
1205 | 7 | 29 | 1196 1995 OCT [15] GENERAL PHARMACOLOGY 26(6):1243-1247 KROGER H; KLEWER M; GRATZ R; DIETRICH A; OCKENFELS H; MIESEL R EXACERBATION OF ACETAMINOPHEN HEPATOTOXICITY BY THALIDOMIDE AND PROTECTION BY NICOTINIC-ACID AMIDE | 1 | 2 |
1206 | 3 | 15 | 1202 1995 OCT [15] JOURNAL OF INFECTIOUS DISEASES 172(4):1137-1140 PETERSON PK; HU SX; SHENG WS; KRAVITZ FH; MOLITOR TW; CHATTERJEE D; CHAO CC THALIDOMIDE INHIBITS TUMOR-NECROSIS-FACTOR-ALPHA PRODUCTION BY LIPOPOLYSACCHARIDE-STIMULATED AND LIPOARABINOMANNAN-STIMULATED HUMAN MICROGLIAL CELLS | 20 | 32 |
1207 | 6 | 23 | 1212 1995 OCT [15] MICROBIAL PATHOGENESIS 19(4):245-255 BURROUGHS MH; TSENOVABERKOVA L; SOKOL K; OSSIG J; TUOMANEN E; KAPLAN G EFFECT OF THALIDOMIDE ON THE INFLAMMATORY RESPONSE IN CEREBROSPINAL-FLUID IN EXPERIMENTAL BACTERIAL-MENINGITIS | 10 | 19 |
1208 | 6 | 25 | 1175 1995 NOV 1 BLOOD 86(9):3604-3609 PARKER PM; CHAO N; NADEMANEE A; ODONNELL MR; SCHMIDT GM; SNYDER DS; STEIN AS; SMITH EP; MOLINA A; STEPAN DE; KASHYAP A; PLANAS I; SPIELBERGER R; SOMLO G; MARGOLIN K; ZWINGENBERGER K; WILSMAN K; NEGRIN RS; LONG GD; NILAND JC; BLUME KG; FORMAN SJ THALIDOMIDE AS SALVAGE THERAPY FOR CHRONIC GRAFT-VERSUS-HOST DISEASE | 51 | 85 |
1209 | 0 | 0 | 1209 1995 NOV 11 LANCET 346(8985):1289-1289 THOMPSON C THALIDOMIDE EFFECTIVE FOR AIDS-RELATED ORAL ULCERS | 5 | 10 |
1210 | 0 | 0 | 1176 1995 NOV 15 BLOOD 86(10):1577-1577 Browne PV; Wagner J; Weisdorf DJ; DeFor T; Miller WJ; Davies SM; Filipovich A; McGlave PB; Ramsay NKC; Enright H Response to thalidomide therapy in patients with refractory chronic graft-versus-host disease. | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1211 | 11 | 31 | 1191 1995 NOV [15] EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 49(1-2):1-6 HARLAND CC; STEVENTON GB; MARSDEN JR THALIDOMIDE INDUCED NEUROPATHY AND GENETIC-DIFFERENCES IN DRUG-METABOLISM | 20 | 23 |
1212 | 1 | 1 | 1193 1995 NOV [15] EXPERIMENTAL HEMATOLOGY 23(12):1324-1324 FERNANDEZ LP; SCHLEGEL PG; BAKER J; CHEN YF; CHAO NJ DOES THALIDOMIDE AFFECT IL-2 RESPONSE AND PRODUCTION (VOL 23, PG 978, 1995) | 1 | 1 |
1213 | 10 | 25 | 1199 1995 NOV [15] IMMUNOPHARMACOLOGY 31(1):109-116 SHANNON EJ; SANDOVAL F THALIDOMIDE INCREASES THE SYNTHESIS OF IL-2 IN CULTURES OF HUMAN MONONUCLEAR-CELLS STIMULATED WITH CONCANAVALIN-A, STAPHYLOCOCCAL-ENTEROTOXIN-A, AND PURIFIED PROTEIN DERIVATIVE | 34 | 37 |
1214 | 3 | 6 | 1207 1995 NOV [15] JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 33(5):837-838 BERGER TG; HOFFMAN C; THIEBERG MD PRURIGO NODULARIS AND PHOTOSENSITIVITY IN AIDS - TREATMENT WITH THALIDOMIDE | 13 | 22 |
1215 | 0 | 0 | 1213 1995 NOV [15] MOLECULAR BIOLOGY OF THE CELL 6:1195-1195 DESESSO JM; HARRIS SB; SCIALLI AR; GOERINGER GC EARLY MICROSCOPIC OBSERVATIONS OF THALIDOMIDE-INDUCED LIMB DEFECTS IN NEW-ZEALAND WHITE-RABBITS | 0 | 0 |
1216 | 0 | 0 | 1221 1995 NOV-DEC [NOV 15] SEARCH 26(10):290-290 WESTMORE A HEREDITY OF THALIDOMIDE DEFORMITY DISPUTED | 0 | 0 |
1217 | 4 | 22 | 1170 1995 DEC [15] ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 39(12):2807-2809 PETERSON PK; GEKKER G; BORNEMANN M; CHATTERJEE D; CHAO CC THALIDOMIDE INHIBITS LIPOARABINOMANNAN-INDUCED UP-REGULATION OF HUMAN-IMMUNODEFICIENCY-VIRUS EXPRESSION | 3 | 10 |
1218 | 4 | 31 | 1194 1995 DEC [15] FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY 12(3-4):165-174 GEIST C; WOHRMANN T; SCHNEIDER J; ZWINGENBERGER K EFFECTS OF THALIDOMIDE ON THE LOCAL SHWARTZMAN REACTION IN MICE AND RABBITS | 6 | 8 |
1219 | 5 | 19 | 1201 1995 DEC 15 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 674(2):287-292 Weinz C; Blaschke G Investigation of the in vitro biotransformation and simultaneous enantioselective separation of thalidomide and its neutral metabolites by capillary electrophoresis | 11 | 24 |
1220 | 18 | 38 | 1210 1995 DEC 15 LIFE SCIENCES 58(4):295-316 Neubert R; Hinz N; Thiel R; Neubert D Down-regulation of adhesion receptors on cells of primate embryos as a probable mechanism of the teratogenic action of thalidomide | 3 | 7 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1221 | 14 | 24 | 1211 1995 DEC 15 LIFE SCIENCES 58(4):337-348 Nogueira AC; Neubert R; Felies A; JacobMuller U; Frankus E; Neubert D Thalidomide derivatives and the immune system .6. Effects of two derivatives with no obvious teratogenic potency on the pattern of integrins and other surface receptors on blood cells of marmosets | 2 | 3 |
1222 | 0 | 0 | 1217 1995 DEC [15] NATURE MEDICINE 1(12):1230-1230 GERSHON D FINDING NEW USES FOR THALIDOMIDE | 3 | 5 |
1223 | 4 | 5 | 1238 1996 JAN [15] ARCHIVES OF DISEASE IN CHILDHOOD 74(1):64-65 Soler RA; Migliorati C; vanWaes H; Nadal D Thalidomide treatment of mucosal ulcerations in HIV infection | 11 | 14 |
1224 | 0 | 0 | 1294 1996 JAN-FEB [JAN 15] REPRODUCTIVE TOXICOLOGY 10(1):1-2 Robert E Thalidomide and isotretinoin - Why treat them differently? | 2 | 6 |
1225 | 0 | 0 | 1227 1996 FEB [15] AIDS PATIENT CARE AND STDS 10(1):51-51 [Anon] Thalidomide effective in treating AIDS-related mouth ulcers | 0 | 0 |
1226 | 9 | 12 | 1230 1996 FEB 15 AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY 53(4):368-& Weidle PJ Thalidomide for aphthous ulcers in patients infected with the human immunodeficiency virus | 5 | 5 |
1227 | 11 | 16 | 1231 1996 FEB 15 AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY 53(4):429-431 Minor JR; Piscitelli SC Thalidomide in diseases associated with human immunodeficiency virus infection | 3 | 4 |
1228 | 10 | 13 | 1249 1996 FEB [15] BONE MARROW TRANSPLANTATION 17(2):291-293 Forsyth CJ; Cremer PD; Torzillo P; Iland HJ; Young GAR Thalidomide responsive chronic pulmonary GVHD | 8 | 14 |
1229 | 23 | 39 | 1258 1996 FEB [15] DEVELOPMENT GROWTH & DIFFERENTIATION 38(1):47-57 Audit CO; Eger K; Aimar C Possible involvement of an acylation mechanism in thalidomide-induced teratogenesis of the newt (Pleurodeles waltl) | 2 | 2 |
1230 | 0 | 0 | 1272 1996 FEB 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 37(3):546-546 Ozaki S; Yamana T; Kita M; Honda Y Effect of thalidomide on experimental choroidal neovascularization in pigmented rats | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1231 | 0 | 0 | 1273 1996 FEB 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 37(3):572-572 Tsujikawa M; Saito Y; Tatebayashi M; Tano Y The inhibitory effect of thalidomide for experimental preretinal neovascularization by laser-induced venous occlusion in rats. | 0 | 0 |
1232 | 0 | 0 | 1274 1996 FEB 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 37(3):3032-3032 Lansing MB; Dixit S; Glaser BM The effect of systemic thalidomide and amiloride on neovascularization in the rabbit corneal micropocket essay | 0 | 0 |
1233 | 0 | 0 | 1275 1996 FEB 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 37(3):4015-4015 Zhang EP; Pleyer U; Hoffmann F; Hartmann C Effect of thalidomide on experimental keratoplasty | 0 | 0 |
1234 | 4 | 5 | 1287 1996 FEB [15] NATURE MEDICINE 2(2):132-132 Crawford CL Thalidomide neuropathy | 1 | 1 |
1235 | 0 | 0 | 1288 1996 FEB [15] NEUROLOGY 46(2):3015-3015 Openshaw H; Slatkin NE; Parker P Thalidomide neuropathy in bone marrow transplantation | 0 | 0 |
1236 | 0 | 0 | 1289 1996 FEB [15] NEUROLOGY 46(2):27003-27003 Chaudhry V; Cornblath D; Corse A; Freimer M; SimmonsOBrien E; Vogelsang G Thalidomide-induced neuropathy: Clinical and electrophysiological features | 0 | 0 |
1237 | 0 | 6 | 1296 1996 FEB [15] SLEEP 19(2):116-116 Kanbayashi T; Nishino S; Tafti M; Hishikawa Y; Dement WC; Mignot E Thalidomide, immune modulation and narcolepsy | 0 | 2 |
1238 | 9 | 28 | 1267 1996 MAR [15] IMMUNOPHARMACOLOGY 31(2-3):213-221 Geitz H; Handt S; Zwingenberger K Thalidomide selectively modulates the density of cell surface molecules involved in the adhesion cascade | 70 | 89 |
1239 | 4 | 17 | 1251 1996 MAR 19 CANCER LETTERS 101(1):21-24 Pollard M Thalidomide promotes metastasis of prostate adenocarcinoma cells (PA-III) in L-W rats | 8 | 12 |
1240 | 2 | 5 | 1283 1996 APR 6 LANCET 347(9006):974-974 Verberkmoes A; Boer K; Wertheim PME; Bronkhorst CM; Lange JMA Thalidomide for genital ulcer in HIV-positive woman | 4 | 9 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1241 | 11 | 43 | 1269 1996 APR [15] INFLAMMATION 20(2):203-215 Kroger H; Miesel R; Dietrich A; Ohde M; Rajnavolgyi E; Ockenfels H Synergistic effects of thalidomide and poly(ADP-ribose) polymerase inhibition on type II collagen-induced arthritis in mice | 1 | 12 |
1242 | 0 | 0 | 1278 1996 APR [15] JOURNAL OF INVESTIGATIVE DERMATOLOGY 106(4):845-845 Smith C; Friednash M; Nguyen C; Knauf T; Walsh P Failure of thalidomide as an anti-angiogenesis factor in a murine melanoma model | 2 | 3 |
1243 | 2 | 7 | 1295 1996 APR [15] REVISTA CLINICA ESPANOLA 196(4):270-271 Tercedor J; delaTorre ML; Rodenas JM Disseminated xanthoma with insipid diabetes: Therapeutic failure of thalidomide | 0 | 0 |
1244 | 0 | 0 | 1262 1996 APR 30 FASEB JOURNAL 10(6):303-303 Shannon EJ; Sandoval F; Krahenbuhl J Hydrolysis of thalidomide abrogates its ability to enhance IL-2 or to suppress TNF-alpha. | 0 | 0 |
1245 | 10 | 18 | 1235 1996 MAY [15] ANTI-CANCER DRUGS 7(3):339-343 Minchinton AI; Fryer KH; Wendt KR; Clow KA; Hayes MMM The effect of thalidomide on experimental tumors and metastases | 29 | 50 |
1246 | 10 | 14 | 1292 1996 MAY [15] PEDIATRIC INFECTIOUS DISEASE JOURNAL 15(5):465-467 DeVincenzo JP; Burchet SK Prolonged thalidomide therapy for human immunodeficiency virus-associated recurrent severe esophageal and oral aphthous ulcers | 5 | 7 |
1247 | 0 | 0 | 1229 1996 JUN 1 AMERICAN JOURNAL OF EPIDEMIOLOGY 143(11):6-6 Yang Q; Khoury MJ; James LM; Olney RS; Paulozzi LJ The return of thalidomide? Are birth defects surveillance systems ready? | 0 | 1 |
1248 | 1 | 5 | 1259 1996 JUN [15] ENDOSCOPY 28(5):471-472 Louvel D; Musso S; Metivier S; Croizet O; Rouquet RM; Massip P; Escourrou J; Frexinos J Idiopathic esophageal ulceration associated with human immunodeficiency virus infection: Efficacy of thalidomide treatment | 0 | 1 |
1249 | 8 | 34 | 1264 1996 JUN [15] HEPATOLOGY 23(6):1616-1621 LopezTalavera JC; Cadelina G; Olchowski J; Merrill W; Groszmann RJ Thalidomide inhibits tumor necrosis factor alpha decreases nitric oxide synthesis, and ameliorates the hyperdynamic circulatory syndrome in portal-hypertensive rats | 7 | 52 |
1250 | 23 | 76 | 1280 1996 JUN [15] JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 277(3):1649-1658 Arlen RR; Wells PG Inhibition of thalidomide teratogenicity by acetylsalicylic acid: Evidence for prostaglandin H synthase-catalyzed bioactivation of thalidomide to a teratogenic reactive intermediate | 9 | 15 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1251 | 10 | 20 | 1281 1996 JUN [15] JOURNAL OF SURGICAL RESEARCH 63(1):143-146 Schmidt H; Rush B; Simonian G; Murphy T; Hsieh J; Condon M Thalidomide inhibits TNF response and increases survival following endotoxin injection in rats | 8 | 17 |
1252 | 3 | 13 | 1233 1996 [JUN 30] ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE 123(6-7):375-377 Cherouati K; Claudy A; Souteyrand P; Cambazard F; Vaillant L; Moulin G; Crickx B; Morel P; Lamorelle A; Revuz J Thalidomide treatment of chronic erythema multiforme recurrent and continuous variants. A retrospective study of 26 patients. | 6 | 7 |
1253 | 8 | 65 | 1246 1996 [JUN 30] BIOGENIC AMINES 12(4):305-326 Audit CO Specific functions of polyamines: Actin assembly, cytokinesis induction, targets for thalidomide activity, nitrogen sources for marine ecosystems | 1 | 3 |
1254 | 13 | 28 | 1252 1996 [JUN 30] CHIRALITY 8(1):11-17 Reepmeyer JC Separation of R-and S-thalidomide by reversed-phase HPLC with beta-cyclodextrin in the mobile phase | 6 | 18 |
1255 | 15 | 22 | 1253 1996 [JUN 30] CHIRALITY 8(5):390-396 Wnendt S; Finkam M; Winter W; Ossig J; Raabe G; Zwingenberger K Enantioselective inhibition of TNF-alpha release by thalidomide and thalidomide-analogues | 27 | 33 |
1256 | 8 | 9 | 1257 1996 [JUN 30] DERMATOLOGY 193(4):321-323 Bonnetblanc JM; Royer C; Bedane C Thalidomide and recurrent aphthous stomatitis: A follow-up study | 5 | 10 |
1257 | 4 | 22 | 1268 1996 [JUN 30] IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 18(1):59-72 Shannon EJ; Sandoval F Thalidomide can be either agonistic or antagonistic to LPS evoked synthesis of TNF-alpha by mononuclear cells | 21 | 24 |
1258 | 6 | 33 | 1276 1996 [JUN 30] JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY 11(3):247-257 Klausner JD; Makonkawkeyoon S; Akarasewi P; Nakata K; Kasinrerk W; Corral L; Dewar RL; Lane HC; Freedman VH; Kaplan G The effect of thalidomide on the pathogenesis of human immunodeficiency virus type 1 and M-tuberculosis infection | 51 | 125 |
1259 | 83 | 215 | 1277 1996 [JUN 30] JOURNAL OF INFLAMMATION 46(4):177-211 Zwingenberger K; Wnendt S Immunomodulation by thalidomide: Systematic review of the literature and of unpublished observations | 33 | 38 |
1260 | 1 | 2 | 1239 1996 JUL [15] ARCHIVES OF DISEASE IN CHILDHOOD 75(1):90-90 Harry TC Thalidomide treatment of mucosal ulcerations in HIV infection | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1261 | 18 | 24 | 1260 1996 JUL-AUG [JUL 15] EUROPEAN JOURNAL OF DERMATOLOGY 6(5):373-376 Charue D; Chauvin E; Duguet C; Revuz J; Bagot M Thalidomide decreases the production of GM-CSF and TNF-alpha in the mixed epidermal cell-lymphocyte reaction | 1 | 2 |
1262 | 8 | 21 | 1286 1996 JUL [15] MOLECULAR MEDICINE 2(4):506-515 Corral LG; Muller GW; Moreira AL; Chen YX; Wu MD; Stirling D; Kaplan G Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity | 43 | 62 |
1263 | 5 | 21 | 1244 1996 JUL 16 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 224(2):426-430 Miyachi H; Azuma A; Hioki E; Iwasaki S; Kobayashi Y; Hashimoto Y Inducer-specific bidirectional regulation by thalidomide and phenylphthalimides of tumor necrosis factor-alpha production | 15 | 25 |
1264 | 13 | 32 | 1293 1996 JUL 23 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(15):7552-7556 Turk BE; Jiang H; Liu JO Binding of thalidomide to alpha(1)-acid glyeoprotein may be involved in its inhibition of tumor necrosis factor alpha production | 39 | 47 |
1265 | 5 | 25 | 1291 1996 AUG 12 NEUROREPORT 7(12):1881-1886 Kanbayashi T; Nishino S; Tafti M; Hishikawa Y; Dement WC; Mignot E Thalidomide, a hypnotic with immune modulating properties, increases cataplexy in canine narcolepsy | 1 | 6 |
1266 | 0 | 0 | 1228 1996 AUG [15] AIDS PATIENT CARE AND STDS 10(4):263-263 [Anon] Thalidomide trial for diarrhea | 0 | 0 |
1267 | 24 | 33 | 1285 1996 AUG [15] LUPUS 5(4):257-258 Stevens RJ The place of thalidomide in the treatment of inflammatory disease | 3 | 5 |
1268 | 17 | 26 | 1279 1996 AUG 16 JOURNAL OF MEDICINAL CHEMISTRY 39(17):3238-3240 Muller GW; Corral LG; Shire MG; Wang H; Moreira A; Kaplan G; Stirling DI Structural modifications of thalidomide produce analogs with enhanced tumor necrosis factor inhibitory activity | 33 | 48 |
1269 | 9 | 11 | 1250 1996 AUG 17 BRITISH MEDICAL JOURNAL 313(7054):377-378 Powell RJ New roles for thalidomide | 18 | 24 |
1270 | 0 | 0 | 1223 1996 AUG 25 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 212:140-MEDI Niwayama S; Turk B; Liu J Potent inhibition of tumor necrosis factor-alpha by tetrafluoro-thalidomide and tetrafluorophthalimides | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1271 | 7 | 14 | 1245 1996 SEP 13 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 226(2):439-444 Miyachi H; Azuma A; Hioki E; Iwasaki S; Kobayashi Y; Hashimoto Y Cell type-/inducer-specific bidirectional regulation by thalidomide and phenylphthalimides of tumor necrosis factor-alpha production and its enantio-dependence | 13 | 20 |
1272 | 10 | 22 | 1240 1996 SEP [15] ARCHIVES OF TOXICOLOGY 70(11):749-756 Schmahl HJ; Dencker L; Plum C; Chahoud I; Nau H Stereoselective distribution of the teratogenic thalidomide analogue EM12 in the early embryo of marmoset monkey, Wistar rat and NMRI mouse | 3 | 7 |
1273 | 0 | 0 | 1241 1996 SEP [15] ARTHRITIS AND RHEUMATISM 39(9):1352-1352 Stevens RJ; Andujar C; Edwards C; Ames PRJ; Barwick AR; Khamashta MA; Hughes GRV Thalidomide in the treatment of cutaneous manifestations of lupus erythematosus. | 0 | 1 |
1274 | 0 | 0 | 1242 1996 SEP [15] ARTHRITIS AND RHEUMATISM 39(9):1353-1353 Sato EI; Assis LSS; Furtado R Long-term thalidomide therapy for cutaneous lesions of systemic lupus erythematosus (SLE) | 0 | 0 |
1275 | 0 | 0 | 1243 1996 SEP [15] ARTHRITIS AND RHEUMATISM 39(9):1524-1524 Lee S; Klausner J; Oliver S; Kaplan G; McCullagh E Treatment of rheumatoid arthritis (RA) with thalidomide | 1 | 1 |
1276 | 5 | 13 | 1255 1996 SEP [15] CLINICAL INFECTIOUS DISEASES 23(3):501-503 Soler RA; Howard M; Brink NS; Gibb D; Tedder RS; Nadal D Regression of AIDS-related Kaposi's sarcoma during therapy with thalidomide | 24 | 31 |
1277 | 2 | 12 | 1256 1996 SEP [15] CLINICAL INFECTIOUS DISEASES 23(3):504-505 Levine AM Editorial response - Regression of AIDS-related Kaposi's sarcoma during therapy with thalidomide | 1 | 1 |
1278 | 2 | 14 | 1261 1996 SEP [15] EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY 8(9):929-931 Postema PTE; denHaan P; vanHagen PM; vanBlankenstein M Treatment of colitis in Behcet's disease with thalidomide | 12 | 19 |
1279 | 11 | 14 | 1270 1996 SEP [15] INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 111(1):13-17 SantosMendoza T; FavilaCastillo L; Oltra A; Tamariz J; Labarrios F; EstradaParra S; EstradaGarcia I Thalidomide and its metabolites have no effect on human lymphocyte proliferation | 7 | 9 |
1280 | 9 | 51 | 1297 1996 SEP [15] TERATOLOGY 54(3):126-134 Smith DM; Torres RD; Stephens TD Mesonephros has a role in limb development and is related to thalidomide embryopathy | 0 | 5 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1281 | 2 | 4 | 1232 1996 OCT [15] AMERICAN JOURNAL OF OPHTHALMOLOGY 122(4):594-595 Ip M; Gorin MB Recurrence of a choroidal neovascular membrane in a patient with punctate inner choroidopathy treated with daily doses of thalidomide | 4 | 13 |
1282 | 0 | 0 | 1290 1996 OCT [15] NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 22(5):456-456 Chakrabarty A; Bridges LR Cerebral malformation in a patient with thalidomide related phocomelia | 0 | 0 |
1283 | 0 | 0 | 1224 1996 NOV [15] AIDS 10:P60-P60 FeregrinoGoyos M; GomezCaro WH; AlvaradoDiez R; Yieyra MPM; TorrasGiner V Thalidomide and ketoprofen reduce the incidence of adverse events of interleukin 2 and enhance the antiviral activity of CD8 in HIV/AIDS patients. | 0 | 0 |
1284 | 0 | 0 | 1225 1996 NOV [15] AIDS 10:P102-P102 MacRedmond R; Keating S; Armstrong S; Ryan M; Mulcahy FM The use of oral thalidomide in the treatment of oesophageal ulceration in AIDS. | 0 | 0 |
1285 | 6 | 38 | 1226 1996 NOV [15] AIDS 10(13):1501-1507 ReyesTeran G; SierraMadero JG; delCerro VM; ArroyoFigueroa H; Pasquetti A; Calva JJ; RuizPalacios GM Effects of thalidomide on HIV-associated wasting syndrome: A randomized, double-blind, placebo-controlled clinical trial | 49 | 97 |
1286 | 5 | 14 | 1234 1996 NOV [15] ANNALS OF THE RHEUMATIC DISEASES 55(11):833-836 Huizinga TWJ; Dijkmans BAC; vanderVelde EA; Kraan TCTMV; Verweij CL; Breedveld FC An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis | 20 | 37 |
1287 | 4 | 25 | 1236 1996 NOV-DEC [NOV 15] ANTICANCER RESEARCH 16(6B):3673-3677 Gutman M; Szold A; Ravid A; Lazauskas T; Merimsky O; Klausner JM Failure of thalidomide to inhibit tumor growth and angiogenesis in vivo | 16 | 23 |
1288 | 2 | 3 | 1237 1996 NOV [15] ARCHIVES OF DERMATOLOGY 132(11):1392-1393 Dereure O; BassetSeguin N; Guilhou JJ Erosive lichen planus: Dramatic response to thalidomide | 14 | 24 |
1289 | 0 | 0 | 1247 1996 NOV 15 BLOOD 88(10):2423-2423 Flowers MED; Tapscott SJ; Emerson J; Emerson MV; Reagan T; Taylor L; Ajer T; Siadak M; Sanders J; Zwingenberger K; Willsmann K; Appelbaum F; Sullivan KM Incidence of peripheral neuropathy (PN) prior to thalidomide treatment for chronic graft-versus-host disease (GVHD). | 0 | 0 |
1290 | 0 | 0 | 1248 1996 NOV 15 BLOOD 88(10):2424-2424 Kulkarni S; Powles R; Mehta J; Horton C; Treleaven J; Middleton G; Eisen T; Singhal S Thalidomide for acute or chronic graft-versus-host disease. | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1291 | 0 | 0 | 1265 1996 NOV [15] IMMUNOLOGY 89:ORI27-ORI27 Marriott JB; Cookson S; Westby M; Guckian M; Dalgleish AG The effect of a thalidomide analogue on TNF-alpha/cytokine production in vitro | 0 | 0 |
1292 | 0 | 0 | 1266 1996 NOV [15] IMMUNOLOGY 89:E51-E51 Guckian M; Marriott JB; Cookson S; Westby M; Dalgleish G Thalidomide analog 3052 reduces NK activity and PHA-induced proliferation in vitro. | 0 | 0 |
1293 | 2 | 13 | 1271 1996 NOV-DEC [NOV 15] INTERNATIONAL JOURNAL OF STD & AIDS 7(7):518-520 Lewis DA; Amerasinghe CN; Murphy SM Successful treatment of Behcet's syndrome in an African female patient with thalidomide | 2 | 3 |
1294 | 0 | 0 | 1284 1996 NOV 16 LANCET 348(9038):1370-1370 Barnett AA FDA encourages firms to test thalidomide | 0 | 0 |
1295 | 10 | 36 | 1254 1996 DEC [15] CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY 81(3):219-223 Klausner JD; Freedman VH; Kaplan G Thalidomide as an anti-TNF-alpha inhibitor: Implications for clinical use | 39 | 56 |
1296 | 9 | 14 | 1263 1996 DEC [15] GASTROINTESTINAL ENDOSCOPY 44(6):729-731 Bellomo A; SchorrLesnick B Thalidomide treatment for idiopathic esophageal ulcers in patients with HIV | 0 | 1 |
1297 | 86 | 101 | 1282 1996 DEC [15] JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 35(6):969-979 Tseng S; Pak G; Washenik K; Pomeranz MK; Shupack JL Rediscovering thalidomide: A review of its mechanism of action, side effects, and potential uses | 76 | 114 |
1298 | 8 | 17 | 1298 1996 DEC [15] TERATOLOGY 54(6):273-277 Castilla EE; AshtonProlla P; BarredaMejia E; Brunoni D; Cavalcanti DP; CorreaNeto J; Delgadillo JL; Dutra MG; Felix T; Giraldo A; Juarez N; LopezCamelo JS; Nazer J; Orioli IM; Paz JE; Pessoto MA; PinaNeto JM; Quadrelli R; Rittler M; Rueda S; Saltos M; Sanchez O; Schuler L Thalidomide, a current teratogen in South America | 14 | 17 |
1299 | 0 | 0 | 1365 1997 JAN 11 LANCET 349(9045):111-111 Barnett AA Company applies to market thalidomide in USA | 0 | 0 |
1300 | 10 | 11 | 1306 1997 JAN [15] AMERICAN JOURNAL OF GASTROENTEROLOGY 92(1):169-170 Ball SC; Sepkowitz KA; Jacobs JL Thalidomide for treatment of oral aphthous ulcers in patients with human immunodeficiency virus: Case report and review | 12 | 13 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1301 | 2 | 5 | 1317 1997 JAN [15] BONE MARROW TRANSPLANTATION 19(1):95-96 Chen F; Tsang K; Liang R Thalidomide-responsive chronic pulmonary GVHD | 0 | 0 |
1302 | 14 | 21 | 1322 1997 JAN [15] CHEMTECH 27(1):21-25 Muller GW Thalidomide: From tragedy to new drug discovery | 4 | 9 |
1303 | 12 | 22 | 1339 1997 JAN [15] IMMUNOPHARMACOLOGY 35(3):203-212 Shannon EJ; Morales MJ; Sandoval F Immunomodulatory assays to study structure-activity relationships of thalidomide | 10 | 13 |
1304 | 0 | 0 | 1355 1997 JAN [15] JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 99(1):679-679 James DE; Jaffarian A; Biggs DF The effects of thalidomide on TNF alpha production from guinea pig alveolar macrophages in vitro and on airways' hyperresponsiveness in vivo. | 0 | 0 |
1305 | 0 | 0 | 1376 1997 JAN [15] NATURE MEDICINE 3(1):8-8 Cimons M Thalidomide resurfaces for FDA consideration | 1 | 1 |
1306 | 5 | 32 | 1384 1997 JAN [15] RESPIRATORY MEDICINE 91(1):31-39 Tavares JL; Wangoo A; Dilworth P; Marshall B; Kotecha S; Shaw RJ Thalidomide reduces tumour necrosis factor-alpha production by human alveolar macrophages | 23 | 38 |
1307 | 5 | 9 | 1372 1997 JAN 23 NATURE 385(6614):303-304 Wnendt S; Zwingenberger K Thalidomide's chirality | 9 | 16 |
1308 | 2 | 8 | 1333 1997 19980203-20:03:43 [FEB 03] DERMATOLOGY 195(4):359-361 Ferrandiz C; Carrascosa JM; Just M; Bielsa I; Ribera M Sequential combined therapy with thalidomide and narrow-band (TLO1) UVB in the treatment of prurigo nodularis | 9 | 11 |
1309 | 0 | 2 | 1385 1997 FEB 3 SCIENTIST 11(3):1-& Brown KS New uses for thalidomide yielding valuable lessons | 1 | 4 |
1310 | 1 | 1 | 1386 1997 FEB 3 SCIENTIST 11(3):8-8 Brown KS Researchers explore thalidomide's therapeutic potential | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1311 | 0 | 0 | 1330 1997 FEB [15] CLINICAL PHARMACOLOGY & THERAPEUTICS 61(2):PI44-PI44 OToole EA; Nasca MR; Palicharla P; West DP; Woodley DT Thalidomide increases keratinocyte proliferation and chemokine secretion in vitro | 0 | 0 |
1312 | 0 | 0 | 1331 1997 FEB [15] CLINICAL PHARMACOLOGY & THERAPEUTICS 61(2):PIV89-PIV89 Donahue SR; Collins JM; Flockhart DA; Abernethy DR; Trapnell CB Thalidomide pharmacokinetics do not change with chronic administration | 0 | 0 |
1313 | 10 | 12 | 1310 1997 FEB 28 ANALYTICA CHIMICA ACTA 339(1-2):91-97 Simmons BR; Lush RM; Figg WD A reversed-phase high performance liquid chromatography method using solid phase extraction to quantitate thalidomide in human serum | 8 | 10 |
1314 | 8 | 16 | 1302 1997 MAR 1 AIDS RESEARCH AND HUMAN RETROVIRUSES 13(4):301-304 Alexander LN; Wilcox CM A prospective trial of thalidomide for the treatment of HIV-associated idiopathic esophageal ulcers | 25 | 32 |
1315 | 6 | 28 | 1390 1997 19980304-02:04:50 [MAR 04] TUBERCLE AND LUNG DISEASE 78(1):47-55 Moreira AL; Tsenova-Berkova L; Wang J; Laochumroonvorapong P; Freeman S; Freedman VH; Kaplan G Effect of cytokine modulation by thalidomide on the granulomatous response in murine tuberculosis | 21 | 46 |
1316 | 19 | 23 | 1319 1997 MAR [15] BRITISH JOURNAL OF RHEUMATOLOGY 36(3):353-359 Stevens RJ; Andujar C; Edwards CJ; Ames PRJ; Barwick AR; Khamashta MA; Hughes GRV Thalidomide in the treatment of the cutaneous manifestations of lupus erythematosus: Experience in sixteen consecutive patients | 36 | 49 |
1317 | 0 | 0 | 1346 1997 MAR 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38(4):1240-1240 Lesk MR; Ponomarenko S; Filion B; Burnier M Effect of oral thalidomide on prolongation of rabbit sclerostomy function. | 0 | 0 |
1318 | 0 | 2 | 1347 1997 MAR 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38(4):1680-1680 Joussen AM; Kruse FE; Becker M; Rohrschneider K; Volcker HE Thalidomide inhibits angiogenesis induced by vascular endothelial growth factor | 0 | 0 |
1319 | 0 | 0 | 1348 1997 MAR 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38(4):4467-4467 DAmato RJ; Verheul HMW; Panigrahy D; Yuan J Combination antiangiogenic therapy with thalidomide and nonsteroidal anti-inflammatory drugs (NSAIDs) | 0 | 0 |
1320 | 0 | 0 | 1349 1997 MAR 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38(4):5409-5409 Baatz H; Tonnessen B; Pleyer U; Hartmann C Thalidomide inhibits leukocyte-endothelium-interaction in endotoxin-induced uveitis | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1321 | 10 | 16 | 1368 1997 MAR [15] LEPROSY REVIEW 68(1):61-66 Powell RJ; GardnerMedwin JMM Guideline for the clinical use and dispensing of thalidomide (Reprinted from the Postgraduate Medical Journal, vol 70, pg 901-904, 1994) | 1 | 3 |
1322 | 0 | 0 | 1352 1997 APR 1 JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY 14(4):20-20 Welles L; Little R; Wyvill K; Pluda J; Figg W; Lietzau J; Merced T; Humphrey R; Yarchoan R Preliminary results of a phase II study of oral thalidomide in patients with HIV infection and Kaposi's sarcoma (KS) | 2 | 3 |
1323 | 0 | 0 | 1353 1997 APR 1 JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY 14(4):76-76 Bower M; Howard M; Gracie F; Phillips R; Fife K A phase II study of thalidomide for Kaposi's sarcoma: Activity and correlation with KSHV DNA load | 1 | 2 |
1324 | 19 | 42 | 1329 1997 APR [15] CLINICAL NEUROPHARMACOLOGY 20(2):152-164 Zhu J; Bai XF; Mix E; vanderMeide PH; Zwingenberger K; Link H Thalidomide suppresses T-and B-cell responses to myelin antigen in experimental allergic neuritis | 3 | 4 |
1325 | 12 | 21 | 1340 1997 APR [15] IMMUNOPHARMACOLOGY 36(1):9-15 Shannon EJ; Sandoval F; Krahenbuhl JL Hydrolysis of thalidomide abrogates its ability to enhance mononuclear cell synthesis of IL-2 as well as its ability to suppress the synthesis of TNF-alpha | 17 | 18 |
1326 | 0 | 0 | 1358 1997 APR [15] JOURNAL OF INVESTIGATIVE DERMATOLOGY 108(4):179-179 Nasca MR; OToole EA; Palicharla P; West DP; Woodley DT Thalidomide increases both human keratinocyte proliferation and migration | 0 | 0 |
1327 | 0 | 0 | 1359 1997 APR [15] JOURNAL OF INVESTIGATIVE DERMATOLOGY 108(4):721-721 Hughes MH; Brander TR; Aronson IK; Eilers D; Fiedler BC Thalidomide therapy for discoid and systemic lupus erythematosus. | 0 | 0 |
1328 | 0 | 0 | 1360 1997 APR [15] JOURNAL OF INVESTIGATIVE DERMATOLOGY 108(4):797-797 Wong J; Brocato D; Kumar R The effect of thalidomide on murine hemangioendothelioma | 0 | 0 |
1329 | 6 | 6 | 1369 1997 APR [15] M S-MEDECINE SCIENCES 13(4):595-596 Audit CO; Aimar C Thalidomide-induced teratogenesis. | 0 | 0 |
1330 | 14 | 27 | 1314 1997 MAY 15 BIOCHEMICAL PHARMACOLOGY 53(10):1553-1557 Nicolai S; Sies H; Stahl W Stimulation of gap junctional intercellular communication by thalidomide and thalidomide analogs in human skin fibroblasts | 6 | 11 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1331 | 18 | 27 | 1344 1997 MAY [15] INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY 19(5):289-296 Pham-Huy C; Galons H; Voisin J; Zhu JR; Righenzi S; Warnet JM; Claude JR; Duc HT In vitro and in vivo immunosuppressive potential of thalidomide and its derivative, N-hydroxythalidomide, alone and in combination with cyclosporin A | 1 | 1 |
1332 | 12 | 21 | 1345 1997 MAY [15] INTERNATIONAL JOURNAL OF ONCOLOGY 10(5):965-969 Nguyen M; Tran C; Barsky S; Sun JR; McBride W; Pegram M; Pietras R; Love S; Glaspy J Thalidomide and chemotherapy combination: Preliminary results of preclinical and clinical studies | 20 | 26 |
1333 | 24 | 44 | 1380 1997 MAY 22 NEW ENGLAND JOURNAL OF MEDICINE 336(21):1487-1493 Jacobson JM; Greenspan JS; Spritzler J; Ketter N; Fahey JL; Jackson JB; Fox L; Chernoff M; Wu AW; MacPhail LA; Vasquez GJ; Wohl DA Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection | 119 | 191 |
1334 | 6 | 22 | 1324 1997 JUN [15] CLINICAL AND EXPERIMENTAL IMMUNOLOGY 108(3):428-431 Hauschild A; Kroeger H; Mitchison NA; Ugrinovic S; Zwingenberger K Thalidomide therapy of established collagen-induced arthritis (CIA) not accompanied by an evident Th2 shift | 6 | 12 |
1335 | 5 | 5 | 1326 1997 JUN [15] CLINICAL CHEMISTRY 43(6):1094-1095 Eriksson T; Bjorkman S Handling of blood samples for determination of thalidomide | 6 | 6 |
1336 | 4 | 5 | 1327 1997 JUN [15] CLINICAL CHEMISTRY 43(6):1095-1096 Lyon AW; Raisys VA Handling of blood samples for determination of thalidomide - Respond | 0 | 0 |
1337 | 13 | 25 | 1328 1997 JUN [15] CLINICAL INFECTIOUS DISEASES 24(6):1223-1227 Haslett P; Tramontana J; Burroughs M; Hempstead M; Kaplan G Adverse reactions to thalidomide in patients infected with human immunodeficiency virus | 22 | 30 |
1338 | 23 | 41 | 1336 1997 JUN [15] EXPERIMENTAL EYE RESEARCH 64(6):971-978 Kenyon BM; Browne F; DAmato RJ Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization | 96 | 149 |
1339 | 11 | 39 | 1338 1997 JUN [15] GASTROENTEROLOGY 112(6):1823-1829 Sharpstone D; Rowbottom A; Francis N; Tovey G; Ellis D; Barrett M; Gazzard B Thalidomide: A novel therapy for microsporidiosis | 12 | 42 |
1340 | 6 | 35 | 1341 1997 [JUN 30] IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 19(3):313-326 Aseffa A; Dietrich MA; Shannon EJ Effect of thalidomide on apoptosis of lymphocytes and neutrophils | 4 | 5 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1341 | 0 | 0 | 1377 1997 [JUN 30] NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 355(4):545-545 Stahl W; Nicolai S; Sies H Stimulation of gap junctional communication by thalidomide and thalidomide analogs in human skin fibroblasts | 0 | 0 |
1342 | 7 | 13 | 1388 1997 [JUN 30] TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS 17(1):1-5 Huang PHT; McBride WG Interaction of [glutarimide-2-C-14]-thalidomide with rat embryonic DNA in vivo | 7 | 12 |
1343 | 7 | 11 | 1389 1997 [JUN 30] TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS 17(1):R1-R2 Neubert D Never-ending tales of the mode of the teratogenic action of thalidomide | 3 | 5 |
1344 | 12 | 43 | 1303 1997 JUL 1 AIDS RESEARCH AND HUMAN RETROVIRUSES 13(10):857-863 Moreira AL; Corral LG; Ye WG; Johnson B; Stirling D; Muller GW; Freedman VH; Kaplan G Thalidomide and thalidomide analogs reduce HIV type 1 replication in human macrophages in vitro | 36 | 47 |
1345 | 0 | 1 | 1307 1997 JUL 1 AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY 54(13):1485-1486 [Anon] Thalidomide heals HIV-related oral ulcers, but caution is required | 0 | 0 |
1346 | 19 | 23 | 1356 1997 JUL-AUG [JUL 15] JOURNAL OF AOAC INTERNATIONAL 80(4):767-773 Reepmeyer JC; Cox DC Liquid chromatographic determination of thalidomide in tablets, capsules, and raw materials | 0 | 4 |
1347 | 0 | 10 | 1361 1997 JUL-AUG [JUL 15] JOURNAL OF PARENTERAL AND ENTERAL NUTRITION 21(4):233-234 Vromen A; Spira RM; Bercovier H; Berry E; Freund HR Pentoxifylline and thalidomide fail to reduce hepatic steatosis during total parenteral nutrition and bowel rest in the rat | 0 | 2 |
1348 | 0 | 0 | 1350 1997 AUG 6 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 278(5):379-379 Nightingale SL Workshop on thalidomide | 0 | 0 |
1349 | 7 | 25 | 1304 1997 AUG 10 AIDS RESEARCH AND HUMAN RETROVIRUSES 13(12):1047-1054 Haslett P; Hempstead M; Seidman C; Diakun J; Vasquez D; Freedman VH; Kaplan G The metabolic and immunologic effects of short-term thalidomide treatment of patients infected with the human immunodeficiency virus | 36 | 57 |
1350 | 0 | 0 | 1299 1997 AUG [15] AIDS PATIENT CARE AND STDS 11(4):292-292 [Anon] Limited course of thalidomide effective in treating AIDS-related mouth ulcers | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1351 | 0 | 0 | 1300 1997 AUG [15] AIDS PATIENT CARE AND STDS 11(4):292-293 [Anon] Clinical sites initiated for thalidomide aphthous ulcer study | 0 | 0 |
1352 | 0 | 0 | 1301 1997 AUG [15] AIDS PATIENT CARE AND STDS 11(4):296-296 [Anon] Positive results reported for thalidomide in AIDS wasting | 0 | 0 |
1353 | 4 | 4 | 1354 1997 AUG 15 JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY 15(5):392-392 Sharp M; Getty J; Klausner JD Thalidomide use is associated with weight gain in HIV-1-positive clients | 2 | 2 |
1354 | 2 | 3 | 1362 1997 AUG [15] JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION 25(2):250-251 Odeka EB; Miller V Thalidomide in oral Crohn's disease refractory to conventional medical treatment | 17 | 0 |
1355 | 23 | 108 | 1370 1997 AUG [15] MEDICAL HYPOTHESES 49(2):123-131 McCarty MF Thalidomide may impede cell migration in primates by down-regulating integrin beta-chains: Potential therapeutic utility in solid malignancies, proliferative retinopathy, inflammatory disorders, neointimal hyperplasia, and osteoporosis | 17 | 31 |
1356 | 2 | 5 | 1373 1997 SEP 11 NATURE 389(6647):118-118 Ashby J Thalidomide is not a mutagen | 3 | 4 |
1357 | 0 | 0 | 1313 1997 SEP [15] ARTHRITIS AND RHEUMATISM 40(9):210-210 Hamuryudan V; Mat C; Saip S; Ozyazgan Y; Siva A; Yurdakul S; Zwingenberger K; Yazici H Randomised and placebo controlled trial of two different doses of thalidomide in Behcet's syndrome | 0 | 0 |
1358 | 0 | 0 | 1321 1997 SEP 15 CHEMISTRY & INDUSTRY (18):714-714 [Anon] Thalidomide for US | 0 | 0 |
1359 | 0 | 0 | 1335 1997 SEP 15 EUROPEAN CHEMICAL NEWS 68(1780):51-51 [Anon] Celgene - FDA approves thalidomide's use against ENL | 0 | 0 |
1360 | 0 | 0 | 1387 1997 SEP [15] SEARCH 28(8):239-239 [Anon] Inheriting thalidomide deformities | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1361 | 0 | 0 | 1320 1997 SEP 20 BRITISH MEDICAL JOURNAL 315(7110):699-699 Rutter T Thalidomide ban to be lifted in the US | 1 | 1 |
1362 | 0 | 1 | 1366 1997 SEP 20 LANCET 350(9081):873-873 Ault A Thalidomide comes close to US approval | 1 | 1 |
1363 | 0 | 0 | 1337 1997 SEP 29 FORTUNE 136(6):36-& McLean B Thalidomide .2. | 0 | 0 |
1364 | 4 | 29 | 1379 1997 OCT 3 NEUROSCIENCE LETTERS 234(2-3):123-126 Boireau A; Bordier F; Dubedat P; Peny C; Imperato A Thalidomide reduces MPTP-induced decrease in striatal dopamine levels in mice | 0 | 9 |
1365 | 0 | 0 | 1351 1997 OCT 8 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 278(14):1135-1137 Marwick C Thalidomide back - Under strict control | 10 | 13 |
1366 | 3 | 3 | 1381 1997 OCT 9 NEW ENGLAND JOURNAL OF MEDICINE 337(15):1086-1087 Birnkrant D Thalidomide for aphthous ulcers in HIV infection | 1 | 2 |
1367 | 0 | 1 | 1382 1997 OCT 9 NEW ENGLAND JOURNAL OF MEDICINE 337(15):1087-1087 Jacobson JM; Greenspan JS; Spritzler J Thalidomide for aphthous ulcers in HIV infection - Reply | 0 | 0 |
1368 | 0 | 0 | 1308 1997 OCT 15 AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY 54(20):2270-& Miller JL Thalidomide recommended for approval under tight restrictions | 2 | 2 |
1369 | 6 | 35 | 1318 1997 OCT [15] BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH 30(10):1199-1207 Moreira AL; Wang J; Sarno EN; Kaplan G Thalidomide protects mice against LPS-induced shock | 11 | 13 |
1370 | 0 | 0 | 1334 1997 OCT [15] DRUG NEWS & PERSPECTIVES 10(8):506-506 [Anon] Celgene's thalidomide approvable for ENL | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1371 | 9 | 21 | 1342 1997 OCT [15] INFLAMMATION RESEARCH 46(10):392-397 Schneider J; Bruckmann W; Zwingenberger K Extravasation of leukocytes assessed by intravital microscopy: Effect of thalidomide | 5 | 13 |
1372 | 0 | 0 | 1363 1997 OCT 15 JOURNAL OF THE NATIONAL CANCER INSTITUTE 89(20):1480-1481 Saphir A Jekyll and Hyde: A new license for thalidomide? | 5 | 7 |
1373 | 12 | 20 | 1383 1997 OCT [15] ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS 84(4):362-364 Elad S; Galili D; Garfunkel AA; Or R Thalidomide-induced perioral neuropathy | 2 | 3 |
1374 | 0 | 0 | 1311 1997 NOV 15 ANNALS OF INTERNAL MEDICINE 127(10):951-952 Vanchieri C Preparing for thalidomide's comeback | 1 | 1 |
1375 | 0 | 0 | 1315 1997 NOV 15 BLOOD 90(10):1673-1673 Kulkarni S; Powles R; Mehta J; Horton C; Treleaven J; Meller S; Atra A; Pinkerton CR; Singhal S Thalidomide is very effective for chronic GVHD but has no activity in acute GVHD. | 0 | 0 |
1376 | 0 | 0 | 1316 1997 NOV 15 BLOOD 90(10):4423-4423 Mehta P; Gian VG; Smith SP; Beltz SE; Wingard JR Thalidomide is not effective for acute graft-versus-host disease. | 0 | 0 |
1377 | 3 | 9 | 1323 1997 NOV [15] CLINICAL AND EXPERIMENTAL DERMATOLOGY 22(6):297-299 Darvay A; Basarab T; Russell-Jones R Thalidomide-induced toxic pustuloderma | 4 | 8 |
1378 | 31 | 50 | 1325 1997 NOV [15] CLINICAL AND EXPERIMENTAL IMMUNOLOGY 110(2):151-154 McHugh SM; Rowland TL Thalidomide and derivatives: immunological investigations of tumour necrosis factor-alpha (TNF-alpha) inhibition suggest drugs capable of selective gene regulation | 17 | 32 |
1379 | 1 | 236 | 1332 1997 NOV [15] COLUMBIA LAW REVIEW 97(7):2153-2176 Bernstein A Formed by thalidomide: Mass torts as a false cure for toxic exposure | 1 | 6 |
1380 | 11 | 30 | 1357 1997 NOV 15 JOURNAL OF IMMUNOLOGY 159(10):5157-5161 Moller DR; Wysocka M; Greenlee BM; Ma XJ; Wahl L; Flockhart DA; Trinchieri G; Karp CL Inhibition of IL-12 production by thalidomide | 77 | 114 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1381 | 2 | 5 | 1367 1997 NOV 15 LANCET 350(9089):1445-1446 Wettstein AR; Meagher AP Thalidomide in Crohn's disease | 34 | 52 |
1382 | 0 | 0 | 1374 1997 NOV [15] NATURE BIOTECHNOLOGY 15(11):1238-1239 Brower V Thalidomide checks might have saved Redux | 0 | 1 |
1383 | 0 | 0 | 1375 1997 NOV [15] NATURE BIOTECHNOLOGY 15(12):1238-1239 Brower V Thalidomide checks might have saved Redux | 0 | 0 |
1384 | 8 | 29 | 1378 1997 NOV [15] NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 356(5):529-535 Dunzendorfer S; Schratzberger P; Reinisch N; Kahler CM; Wiedermann CJ Effects of thalidomide on neutrophil respiratory burst, chemotaxis, and transmigration of cytokine-and endotoxin-activated endothelium | 17 | 23 |
1385 | 7 | 20 | 1305 1997 DEC 10 AIDS RESEARCH AND HUMAN RETROVIRUSES 13(18):1625-1631 Marriott JB; Cookson S; Carlin E; Youle M; Hawkins DA; Nelson M; Pearson P; Vaughan AN; Gazzard B; Dalgleish AG A double-blind placebo-controlled phase II trial of thalidomide in asymptomatic HIV-positive patients: Clinical tolerance and effect on activation markers and cytokines | 9 | 14 |
1386 | 16 | 59 | 1371 1997 DEC 12 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 396(1-2):45-64 Ashby J; Tinwell H; Callander RD; Kimber I; Clay P; Galloway SM; Hill RB; Greenwood SK; Gaulden ME; Ferguson MJ; Vogel E; Nivard M; Parry JM; Williamson J Thalidomide: lack of mutagenic activity across phyla and genetic endpoints | 12 | 14 |
1387 | 14 | 21 | 1312 1997 DEC [15] ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 41(12):2797-2799 Piscitelli SC; Figg WD; Hahn B; Kelly G; Thomas S; Walker RE Single-dose pharmacokinetics of thalidomide in human immunodeficiency virus-infected patients | 22 | 25 |
1388 | 53 | 74 | 1343 1997 DEC [15] INTERNATIONAL JOURNAL OF DERMATOLOGY 36(12):881-887 Calderon P; Anzilotti M; Phelps R Thalidomide in dermatology. New indications for an old drug | 21 | 26 |
1389 | 0 | 0 | 1364 1997 DEC [15] JOURNAL OF WOMENS HEALTH 6(6):614-615 White K Thalidomide may be approved after decades-long US ban | 0 | 0 |
1390 | 3 | 44 | 1309 1997 DEC 19 AMERICAN JOURNAL OF MEDICAL GENETICS 73(3):251-258 Yang QH; Khoury MJ; James LM; Olney RS; Paulozzi LJ; Erickson JD The return of thalidomide: Are birth defects surveillance systems ready? | 1 | 6 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1391 | 2 | 3 | 1421 1998 JAN 10 BRITISH MEDICAL JOURNAL 316(7125):149-149 Smithells D Dominant gene probably caused some of defects ascribed to thalidomide | 1 | 1 |
1392 | 8 | 26 | 1399 1998 JAN [15] ARCHIV DER PHARMAZIE 331(1):7-12 Teubert U; Zwingenberger K; Wnendt S; Eger K 5 '-substituted thalidomide analogs as modulators of TNF-alpha | 10 | 10 |
1393 | 2 | 5 | 1428 1998 JAN [15] CLINICAL INFECTIOUS DISEASES 26(1):184-185 Gori A; Franzetti F; Marchetti G; Rossi C; Fusi ML; Ruzzante S; Clerici M Clinical and immunological improvement in a patient who received thalidomide treatment for refractory Mycobacterium avium complex infection | 5 | 7 |
1394 | 10 | 55 | 1473 1998 JAN [15] PAIN 74(1):83-91 Sommer C; Marziniak M; Myers RR The effect of thalidomide treatment on vascular pathology and hyperalgesia caused by chronic constriction injury of rat nerve | 5 | 54 |
1395 | 2 | 8 | 1392 1998 FEB 12 AIDS 12(3):334-335 Di Fabio S; Trabattoni D; Geraci A; Ruzzante S; Panzini G; Fusi ML; Chiarotti F; Corrias F; Belli R; Verani P; Dalgleish A; Clerici M Effects of thalidomide therapy in symptomatic simian immunodeficiency virus-infected cynomolgus monkeys | 0 | 0 |
1396 | 13 | 23 | 1424 1998 19980311-21:13:06 [MAR 11] CHIRALITY 10(3):223-228 Eriksson T; Bjorkman S; Roth B; Fyge A; Hoglund P Enantiomers of thalidomide: Blood distribution and the influence of serum albumin on chiral inversion and hydrolysis | 17 | 28 |
1397 | 0 | 0 | 1393 1998 MAR [15] AIDS PATIENT CARE AND STDS 12(3):231-231 [Anon] Thalidomide studied in asymptomatic patients | 0 | 0 |
1398 | 13 | 25 | 1396 1998 MAR 15 ANNALS OF INTERNAL MEDICINE 128(6):443-+ Hamuryudan V; Mat C; Saip S; Ozyazgan Y; Siva A; Yurdakul S; Zwingenberger K; Yazici H Thalidomide in the treatment of the mucocutaneous lesions of the Behcet syndrome - A randomized, double-blind, placebo-controlled trial | 67 | 126 |
1399 | 5 | 19 | 1397 1998 MAR 15 ANNALS OF INTERNAL MEDICINE 128(6):494-495 Ehrlich GE Behcet disease and the emergence of thalidomide | 4 | 19 |
1400 | 0 | 0 | 1416 1998 MAR [15] BONE MARROW TRANSPLANTATION 21:S113-S113 Anagnostopoulos A; Fassas A; Giannaki E; Sakellari I; Tzarou V; Smias C; Lalayanni C; Papaioannou G; Gakos E Treatment of resistant chronic GVHD with thalidomide. | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1401 | 14 | 23 | 1417 1998 MAR [15] BONE MARROW TRANSPLANTATION 21(6):577-581 Rovelli A; Arrigo C; Nesi F; Balduzzi A; Nicolini B; Locasiulli A; Vassallo E; Miniero R; Uderzo C The role of thalidomide in the treatment of refractory chronic graft-versus-host disease following bone marrow transplantation in children | 26 | 36 |
1402 | 37 | 60 | 1433 1998 MAR [15] EXPERIMENTAL HEMATOLOGY 26(3):217-221 Or R; Feferman R; Shoshan S Thalidomide reduces vascular density in granulation tissue of subcutaneously implanted polyvinyl alcohol sponges in guinea pigs | 18 | 24 |
1403 | 0 | 0 | 1436 1998 MAR [15] GEBURTSHILFE UND FRAUENHEILKUNDE 58(3):M55-M58 Kosenow W Forty years ago: Thalidomide and its consequences | 0 | 0 |
1404 | 8 | 14 | 1441 1998 MAR [15] INTERNATIONAL JOURNAL OF LEPROSY AND OTHER MYCOBACTERIAL DISEASES 66(1):61-65 Moreira AL; Kaplan G; Villahermosa LG; Fajardo TJ; Abalos RM; Cellona RV; Balagon MVF; Tan EV; Walsh GP Comparison of pentoxifylline, thalidomide and prednisone in the treatment of ENL | 1 | 9 |
1405 | 12 | 14 | 1453 1998 MAR [15] JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 38(3):490-491 Hecker MS; Lebwohl MG Recalcitrant pyoderma gangrenosum: Treatment with thalidomide | 14 | 21 |
1406 | 8 | 11 | 1475 1998 MAR [15] REVUE DE MEDECINE INTERNE 19(3):196-198 Lair G; Marie I; Cailleux N; Blot E; Boullie MC; Courville P; Lauret P; Levesque H; Courtois H Langerhans cell histiocytosis in adult patients: cutaneous and mucous localizations improving with thalidomide | 9 | 13 |
1407 | 3 | 5 | 1476 1998 MAR [15] REVUE DE MEDECINE INTERNE 19(3):208-209 Grasland A; Pouchot J; Chaumaiziere D; Aitken G; Vinceneux P Effectiveness of thalidomide in cutaneous sarcoidosis | 3 | 4 |
1408 | 0 | 0 | 1434 1998 MAR 17 FASEB JOURNAL 12(4):A262-A262 Rowland TL; McHugh SM; Ewan PW; Lachmann PJ; Dearman RJ; Kimber I Down-regulation of T-cell and non-T-cell derived tumor necrosis factor alpha by thalidomide and dexamethasone | 0 | 0 |
1409 | 0 | 0 | 1435 1998 APR 15 GASTROENTEROLOGY 114(4):A1008-A1008 Kenet G; Avni Y; Aeed H; Shirin H; Matas Z; Zaidel L; Galor S; Hershkovitz R; Bruck R Iodoacetamide-induced colitis in rats is inhibited by thalidomide. | 0 | 0 |
1410 | 0 | 0 | 1447 1998 APR [15] JOURNAL OF INVESTIGATIVE DERMATOLOGY 110(4):516-516 Wolkenstein P; Latarget J; Roujeau JC; Duguet C; Boudeau S; Vaillant L; Maignan M; Milpied B; Bocquet H; Revuz J Randomized double-blind comparison of thalidomide versus placebo in toxic epidermal necrolysis: Overmortality in treated group. | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1411 | 0 | 0 | 1448 1998 APR [15] JOURNAL OF INVESTIGATIVE DERMATOLOGY 110(4):693-693 Brenneman S; Burns R; Vink A; Gaines E; Haake A; Gaspari A Thalidomide inhibits UVB-induced mouse epidermal cell apoptosis by a TNF-alpha dependent pathway. | 0 | 0 |
1412 | 13 | 66 | 1463 1998 APR [15] MEDICAL HYPOTHESES 50(4):313-318 Argiles JM; Carbo N; Lopez-Soriano FJ Was tumour necrosis factor-alpha responsible for the fetal malformations associated with thalidomide in the early 1960s? | 11 | 12 |
1413 | 0 | 0 | 1471 1998 APR [15] NEUROLOGY 50(4):A208-A208 Poncelet AN; Maurer TA; Wu ZQ; Ng J; Badger J; Berger TG Peripheral neuropathy in HIV-infected patients with prurigo nodularis treated with thalidomide: Clinical and electrophysiologic features | 0 | 0 |
1414 | 0 | 0 | 1472 1998 APR [15] NEUROLOGY 50(4):A383-A384 Frennier JM; Abrey LE; Haimovitz-Friedman A; McLoughlin M; Rosenfeld MR Does thalidomide have a role in glioma angiogenesis? | 0 | 0 |
1415 | 1 | 30 | 1457 1998 APR 18 LANCET 351(9110):1197-1199 Dally A Thalidomide: was the tragedy preventable? | 6 | 16 |
1416 | 7 | 20 | 1408 1998 MAY 5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 8(9):1071-1076 Niwayama S; Loh C; Turk BE; Liu JO; Miyachi H; Hashimoto Y Enhanced potency of perfluorinated thalidomide derivatives for inhibition of LPS-induced tumor necrosis factor-alpha production is associated with a change of mechanism of action | 8 | 10 |
1417 | 0 | 0 | 1410 1998 MAY-JUN [MAY 15] BIOTECHNOLOGY LAW REPORT 17(3):361-362 [Anon] FDA grants orphan drug designation to thalidomide as treatment for primary brain cancers | 0 | 0 |
1418 | 9 | 10 | 1426 1998 MAY [15] CLINICAL AND EXPERIMENTAL DERMATOLOGY 23(3):141-141 Georgala S; Katoulis AC; Hasapi V; Koumantaki-Mathioudaki E Thalidomide treatment for hypertrophic lupus erythematosus | 3 | 3 |
1419 | 3 | 25 | 1440 1998 MAY [15] INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 116(1):60-66 Partida-Sanchez S; Favila-Castillo L; Pedraza-Sanchez S; Gomez-Melgar M; Saul A; Estrada-Parra S; Estrada-Garcia I IgG antibody subclasses, tumor necrosis factor and IFN-gamma levels in patients with type II lepra reaction on thalidomide treatment | 9 | 12 |
1420 | 11 | 33 | 1452 1998 MAY [15] JOURNAL OF RHEUMATOLOGY 25(5):964-969 Oliver SJ; Cheng TP; Banquerigo ML; Brahn E The effect of thalidomide and 2 analogs on collagen induced arthritis | 15 | 31 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1421 | 2 | 4 | 1474 1998 MAY [15] PALLIATIVE MEDICINE 12(3):208-209 Deaner P Thalidomide for distressing night sweats in advanced malignant disease | 12 | 13 |
1422 | 2 | 5 | 1458 1998 MAY 23 LANCET 351(9115):1591-1591 Smithells D Was the thalidomide tragedy preventable? | 0 | 0 |
1423 | 1 | 5 | 1459 1998 MAY 23 LANCET 351(9115):1591-1591 Critchley EMR Was the thalidomide tragedy preventable? | 0 | 0 |
1424 | 13 | 27 | 1406 1998 JUN 1 BIOCHEMICAL PHARMACOLOGY 55(11):1827-1834 Bauer KS; Dixon SC; Figg WD Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent | 80 | 120 |
1425 | 23 | 37 | 1444 1998 JUN 1 JOURNAL OF EXPERIMENTAL MEDICINE 187(11):1885-1892 Haslett PAJ; Corral LG; Albert M; Kaplan G Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset | 142 | 177 |
1426 | 5 | 15 | 1407 1998 JUN [15] BIOLOGICAL & PHARMACEUTICAL BULLETIN 21(6):638-640 Ishikawa M; Kanno S; Takayanagi M; Takayanagi Y; Sasaki K Thalidomide promotes the release of tumor necrosis factor-alpha (TNF-alpha) and lethality by lipopolysaccharide in mice | 5 | 6 |
1427 | 26 | 80 | 1430 1998 JUN [15] CURRENT MEDICINAL CHEMISTRY 5(3):163-178 Hashimoto Y Novel biological response modifiers derived from thalidomide | 14 | 36 |
1428 | 13 | 27 | 1437 1998 JUN [15] GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 236(6):461-466 Kruse FE; Joussen AM; Rohrschneider K; Becker MD; Volcker HE Thalidomide inhibits corneal angiogenesis induced by vascular endothelial growth factor | 39 | 57 |
1429 | 9 | 41 | 1446 1998 JUN [15] JOURNAL OF INFECTIOUS DISEASES 177(6):1563-1572 Tsenova L; Sokol K; Freedman VH; Kaplan G Combination of thalidomide plus antibiotics protects rabbits from mycobacterial meningitis-associated death | 14 | 26 |
1430 | 0 | 0 | 1469 1998 19980618-18:57:00 [JUN 18] NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 357(4):R119-R119 Thiel R; Klug S Adhesion receptors on rat limb bud cells after treatment with a thalidomide derivative | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1431 | 21 | 33 | 1439 1998 JUL [15] IMMUNOPHARMACOLOGY 40(1):11-20 Rowland TL; McHugh SM; Deighton J; Dearman RJ; Ewan PW; Kimber I Differential regulation by thalidomide and dexamethasone of cytokine expression in human peripheral blood mononuclear cells | 36 | 48 |
1432 | 0 | 0 | 1460 1998 JUL 25 LANCET 352(9124):298-298 Ault A Thalidomide makes a return to US health care | 0 | 0 |
1433 | 0 | 0 | 1423 1998 AUG 3 CHEMISTRY & INDUSTRY (15):591-591 [Anon] Concern over US thalidomide approval | 1 | 0 |
1434 | 12 | 15 | 1449 1998 19980814-22:02:06 [AUG 14] JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES 21(14):2151-2163 Haque A; Stewart JT Determination of racemic thalidomide in human plasma by use of an avidin column and solid phase extraction | 3 | 5 |
1435 | 4 | 5 | 1400 1998 AUG [15] ARCHIVES OF DERMATOLOGY 134(8):1045-1046 Rousseau L; Beylot-Barry M; Doutre MS; Beylot C Cutaneous sarcoidosis successfully treated with low doses of thalidomide | 12 | 25 |
1436 | 8 | 24 | 1420 1998 AUG [15] BRITISH JOURNAL OF CANCER 78(3):336-343 Ching LM; Browne WL; Tchernegovski R; Gregory T; Baguley BC; Palmer BD Interaction of thalidomide, phthalimide analogues of thalidomide and pentoxifylline with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid: concomitant reduction of serum tumour necrosis factor-alpha and enhancement of anti-tumour activity | 16 | 26 |
1437 | 16 | 33 | 1450 1998 AUG [15] JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 26(4):363-383 Hoglund P; Eriksson T; Bjorkman S A double-blind study of the sedative effects of the thalidomide enantiomers in humans | 11 | 15 |
1438 | 7 | 10 | 1454 1998 AUG [15] JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 39(2):293-295 Warren KJ; Nopper AJ; Crosby DL Thalidomide for recalcitrant discoid lesions in a patient with systemic lupus erythematosus | 7 | 9 |
1439 | 0 | 0 | 1456 1998 AUG [15] JOURNAL OF VASCULAR RESEARCH 35:54-54 Baatz H; Tonnessen B; Pleyer U; Hartmann C Antiinflammatory action of thalidomide: Modulation of leukocyte-endothelium interaction | 0 | 0 |
1440 | 5 | 5 | 1461 1998 AUG 15 LANCET 352(9127):544-545 Stambe C; Wicks IP TNF alpha and response of treatment-resistant adult-onset Still's disease to thalidomide | 10 | 24 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1441 | 0 | 0 | 1468 1998 AUG [15] NATURE BIOTECHNOLOGY 16(8):695-695 [Anon] The problem with thalidomide's new incarnation | 0 | 0 |
1442 | 0 | 0 | 1391 1998 AUG 23 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 216:U267-U267 Swartz GM; Shah JH; Fogler WE; Papathanassiu A; Madsen JW; Green SJ 2-methyl-2-phthalimidino-glutaric acid, a partially-reduced analog of thalidomide, is a potent inhibitor of B16 melanoma metastases. | 0 | 0 |
1443 | 0 | 0 | 1395 1998 SEP 1 AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY 55(17):1746-+ Kepple SR Thalidomide approval brings tight restrictions on access | 1 | 1 |
1444 | 0 | 0 | 1443 1998 SEP 9 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 280(10):872-872 Nightingale SL Thalidomide approved for erythema nodosum leprosum | 9 | 11 |
1445 | 0 | 0 | 1470 1998 19980911-20:45:01 [SEP 11] NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 358(1):R479-R479 Bignone IM; Papale RM; Seoane M; Bazerque PM Thalidomide - New trends for therapeutical use | 0 | 0 |
1446 | 0 | 0 | 1401 1998 SEP [15] ARTHRITIS AND RHEUMATISM 41(9):S60-S60 Scoville CD Open trial using methotrexate and thalidomide in the treatment of rheumatoid arthritis. | 2 | 2 |
1447 | 0 | 0 | 1402 1998 SEP [15] ARTHRITIS AND RHEUMATISM 41(9):S98-S98 Oliver SJ; Freeman SL; Kaplan G Thalidomide and analog CC1089 in rat adjuvant arthritis. | 0 | 0 |
1448 | 0 | 0 | 1403 1998 SEP [15] ARTHRITIS AND RHEUMATISM 41(9):S108-S108 Ordi-Ros J; Cortes F; Martinez N; Montse M; De Torres I; Vilardell M Thalidomide induces amenorrhea in patients with lupus disease. | 0 | 0 |
1449 | 0 | 0 | 1411 1998 SEP-OCT [SEP 15] BIOTECHNOLOGY LAW REPORT 17(5):596-597 [Anon] Notorious teratogen wins FDA approval for leprosy - Thalidomide will be most tightly regulated drug ever | 0 | 0 |
1450 | 6 | 10 | 1427 1998 SEP [15] CLINICAL AND EXPERIMENTAL DERMATOLOGY 23(5):233-235 Herranz P; Pizarro A; de Lucas R; Arribas JR; Garcia-Tobaruela A; Pena JM; Casado M Treatment of AIDS-associated prurigo nodularis with thalidomide | 4 | 5 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1451 | 0 | 0 | 1432 1998 SEP [15] EUROPEAN CYTOKINE NETWORK 9(3):367-367 Corral LG; Haslett PAJ; Ocampo C; Muller GW; Wong ML; Stirling D; Kaplan G Two distinct classes of thalidomide analogues which shape potent TNF-alpha inhibitory activity, modulate other cytokines differently | 0 | 0 |
1452 | 4 | 13 | 1409 1998 OCT 6 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 8(19):2669-2674 Muller GW; Shire MG; Wong LM; Corral LG; Patterson RT; Chen YX; Stirling DI Thalidomide analogs and PDE4 inhibition | 20 | 31 |
1453 | 0 | 0 | 1405 1998 OCT [15] ASM NEWS 64(10):557-558 Fox JL Thalidomide approved for treating leprosy | 1 | 1 |
1454 | 0 | 0 | 1438 1998 OCT [15] HEPATOLOGY 28(4):460A-460A Martinez L; Lopez-Talavera JC; Martinez M; Cadelina G; Pachon JC; Esteban R; Guardia J; Groszmann RJ Amelioration of the hyperdynamic syndrome of cirrhotic rats by thalidomide. | 0 | 0 |
1455 | 14 | 30 | 1445 1998 OCT 15 JOURNAL OF IMMUNOLOGY 161(8):4236-4243 Marriott JB; Westby M; Cookson S; Guckian M; Goodbourn S; Muller G; Shire MG; Stirling D; Dalgleish AG CC-3052: A water-soluble analog of thalidomide and potent inhibitor of activation-induced TNF-alpha production | 33 | 49 |
1456 | 18 | 33 | 1477 1998 OCT [15] SCANDINAVIAN JOURNAL OF IMMUNOLOGY 48(4):397-402 Zhu J; Deng GM; Diab A; Zwingenberger K; Bakhiet M; Link H Thalidomide prolongs experimental autoimmune neuritis in Lewis rats | 4 | 10 |
1457 | 0 | 0 | 1464 1998 OCT 23 MEDICAL LETTER ON DRUGS AND THERAPEUTICS 40(1038):103-104 [Anon] Thalidomide | 1 | 0 |
1458 | 0 | 0 | 1425 1998 OCT 27 CIRCULATION 98(17):247-247 Dibbs ZI; Longo T; Muller GW; Zeldis J; Sivasubramanian N; Mann DL Thalidomide and thalidomide analogs suppress TNF alpha secretion by myocytes | 0 | 0 |
1459 | 8 | 28 | 1462 1998 NOV 14 LANCET 352(9140):1586-1589 Wolkenstein P; Latarjet J; Roujeau JC; Duguet C; Boudeau S; Vaillant L; Maignan M; Schuhmacher MH; Milpied B; Pilorget A; Bocquet H; Brun-Buisson C; Revuz J Randomised comparison of thalidomide versus placebo in toxic epidermal necrolysis | 39 | 78 |
1460 | 4 | 24 | 1398 1998 NOV-DEC [NOV 15] ANTICANCER RESEARCH 18(6A):4409-4413 Browne WL; Wilson WR; Baguley BC; Ching LM Suppression of serum tumour necrosis factor-alpha by thalidomide does not lead to reversal of tumour vascular collapse and anti-tumour activity of 5,6-dimethylxanthenone-4-acetic acid | 5 | 13 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1461 | 0 | 0 | 1412 1998 NOV 15 BLOOD 92(10):235B-235B Costa PT; Leaf RMLV; Morais LO; Ribeiro RA Thalidomide (TLD) and pentoxifylline (PTX) prevent the development of chronic cardiomyopathy provoked by doxorubicin (DXR) in rats without inhibiting its antitumoral effect. | 0 | 2 |
1462 | 0 | 0 | 1413 1998 NOV 15 BLOOD 92(10):279B-279B Lim SH; Maclean R Thalidomide in IgA multiple myeloma. | 0 | 0 |
1463 | 0 | 0 | 1414 1998 NOV 15 BLOOD 92(10):318A-318A Singhal S; Mehta J; Eddlemon P; Gray P; Cromer J; Desikan R; Ayers D; Siegel D; Munshi N; Anaissie E; Kantarjian H; Zeldis J; Barlogie B Marked anti-tumor effect from anti-angiogenesis (AA) therapy with thalidomide (T) in high risk refractory multiple myeloma (MM). | 0 | 20 |
1464 | 0 | 0 | 1415 1998 NOV 15 BLOOD 92(10):344B-344B Kulkarni S; Powles R; Mehta J; Horton C; Treleaven J; Meller S; Atra A; Pinkerton CR; Singhal S Thalidomide in GVHD - S anti-GVHD effect separable from the antiangiogenesis? | 0 | 4 |
1465 | 5 | 7 | 1418 1998 NOV [15] BONE MARROW TRANSPLANTATION 22(9):933-934 Sastry PSRK; Powles RL Thalidomide for chronic GVHD | 0 | 0 |
1466 | 1 | 1 | 1419 1998 NOV [15] BONE MARROW TRANSPLANTATION 22(9):934-934 Kami M; Ogawa S; Mitani K; Hirai H Thalidomide for chronic GVHD - Reply | 0 | 0 |
1467 | 9 | 10 | 1431 1998 NOV [15] DRUG SAFETY 19(5):339-341 Smithells D Does thalidomide cause second generation birth defects? | 4 | 4 |
1468 | 11 | 18 | 1455 1998 NOV [15] JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 39(5):835-838 Lee JB; Koblenzer PS Disfiguring cutaneous manifestation of sarcoidosis treated with thalidomide: A case report | 14 | 29 |
1469 | 2 | 19 | 1465 1998 NOV [15] METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 20(9):739-742 Guinan P; Shaw M; Mirochnik Y; Slobodskoy L; Ray V; Rubenstein M Paclitaxel is more effective than thalidomide in inhibiting LNCaP tumor growth in a prostate cancer model | 2 | 5 |
1470 | 0 | 0 | 1466 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9:200A-200A Wilson K; Lancaster T; Boyd M; Taylor LD Inhibition of cell-cell contacts in T lymphoblastic cells during exposure to thalidomide. | 0 | 0 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1471 | 3 | 9 | 1467 1998 NOV 26 NATURE 396(6709):322-323 Tabin CJ A developmental model for thalidomide defects | 9 | 20 |
1472 | 7 | 10 | 1394 1998 DEC [15] AIDS PATIENT CARE AND STDS 12(12):903-906 Fu CS; Conteas CN; LaRiviere MJ Successful treatment of idiopathic colitis and proctitis using thalidomide in persons infected with human immunodeficiency virus | 2 | 3 |
1473 | 7 | 13 | 1404 1998 DEC [15] ARTHRITIS AND RHEUMATISM 41(12):2273-2275 Ordi J; Cortes F; Martinez N; Mauri M; De Torres I; Vilardell M Thalidomide induces amenorrhea in patients with lupus disease | 12 | 19 |
1474 | 18 | 41 | 1422 1998 DEC [15] CHEMICAL RESEARCH IN TOXICOLOGY 11(12):1521-1528 Reist M; Carrupt PA; Francotte E; Testa B Chiral inversion and hydrolysis of thalidomide: Mechanisms and catalysis by bases and serum albumin, and chiral stability of teratogenic metabolites | 15 | 17 |
1475 | 9 | 27 | 1429 1998 DEC [15] CLINICAL PHARMACOLOGY & THERAPEUTICS 64(6):597-602 Trapnell CB; Donahue SR; Collins JM; Flockhart DA; Thacker D; Abernethy DR Thalidomide does not alter the pharmacokinetics of ethinyl estradiol and norethindrone | 13 | 15 |
1476 | 6 | 28 | 1442 1998 DEC [15] INTERNATIONAL JOURNAL OF STD & AIDS 9(12):751-755 Fife K; Howard MR; Gracie F; Phillips RH; Bower M Activity of thalidomide in AIDS-related Kaposi's sarcoma and correlation with HHV8 titre | 28 | 44 |
1477 | 21 | 27 | 1451 1998 DEC [15] JOURNAL OF PHARMACY AND PHARMACOLOGY 50(12):1409-1416 Eriksson T; Bjorkman S; Roth B; Bjork H; Hoglund P Hydroxylated metabolites of Thalidomide: Formation in-vitro and in-vivo in man | 23 | 24 |
1478 | 79 | 87 | 1478 1998 DEC [15] SEMINARS IN CUTANEOUS MEDICINE AND SURGERY 17(4):231-242 Stirling DI Thalidomide and its impact in dermatology | 14 | 17 |
1479 | 8 | 24 | 1484 1999 JAN [15] AMERICAN JOURNAL OF PUBLIC HEALTH 89(1):98-101 Annas GJ; Elias S Thalidomide and the Titanic: Reconstructing the technology tragedies of the twentieth century | 5 | 7 |
1480 | 7 | 42 | 1521 1999 JAN [15] BRITISH JOURNAL OF CANCER 79(1):114-118 Verheul HMW; Panigrahy D; Yuan J; D'Amato RJ Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits | 16 | 31 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1481 | 6 | 10 | 1552 1999 JAN [15] INTERNATIONAL JOURNAL OF DERMATOLOGY 38(1):76-77 Pizarro A; Garcia-Tobaruela A; Herranz P; Pinilla J Thalidomide as an inhibitor of tumor necrosis factor-alpha production: a word of caution | 1 | 1 |
1482 | 0 | 0 | 1558 1999 JAN [15] JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 103(1):S20-S20 Martinez A; Hernandez T; Hernandez V; Espinosa F Thalidomide for pertinacious vasculitic syndrome secondary to coxsackie A virus infection. | 0 | 0 |
1483 | 12 | 52 | 1559 1999 JAN [15] JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 81B(1):9-23 McCredie J; Willert HG Longitudinal limb deficiencies and the sclerotomes - An analysis of 378 dysmelic malformations induced by thalidomide | 0 | 7 |
1484 | 19 | 28 | 1570 1999 JAN [15] JOURNAL OF PHARMACEUTICAL SCIENCES 88(1):121-125 Figg WD; Raje S; Bauer KS; Tompkins A; Venzon D; Bergan R; Chen A; Hamilton M; Pluda J; Reed E Pharmacokinetics of thalidomide in an elderly prostate cancer population | 33 | 47 |
1485 | 4 | 5 | 1573 1999 JAN 23 LANCET 353(9149):324-324 Klausner JD; Kaplan G; Haslett PAJ Thalidomide in toxic epidermal necrolysis | 7 | 8 |
1486 | 1 | 2 | 1574 1999 JAN 23 LANCET 353(9149):324-324 Levy R Thalidomide in toxic epidermal necrolysis | 1 | 2 |
1487 | 5 | 11 | 1602 1999 FEB 1 SLEEP 22(1):113-115 Kanbayashi T; Shimizu T; Takahashi Y; Kitajima T; Takahashi K; Saito Y; Hishikawa Y Thalidomide increases both REM and stage 3-4 sleep in human adults: A preliminary study | 8 | 10 |
1488 | 8 | 26 | 1498 1999 FEB [15] BIOLOGICAL & PHARMACEUTICAL BULLETIN 22(2):224-226 Shimazawa R; Miyachi H; Takayama H; Kuroda K; Kato F; Kato M; Hashimoto Y Antiangiogenic activity of tumor necrosis factor-alpha production regulators derived from thalidomide | 10 | 16 |
1489 | 6 | 17 | 1532 1999 FEB [15] CLINICAL THERAPEUTICS 21(2):319-330 Zeldis JB; Williams BA; Thomas SD; Elsayed ME STEPS (TM): A comprehensive program for controlling and monitoring access to thalidomide | 37 | 45 |
1490 | 4 | 24 | 1553 1999 FEB [15] INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 80(1):11-16 Arrieta O; Ortiz-Reyes A; Rembao D; Calvillo M; Rivera E; Sotelo J Protective effect of pentoxifylline plus thalidomide against septic shock in mice | 4 | 8 |
# | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
1491 | 13 | 23 | 1569 1999 FEB [15] JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION 28(2):214-216 Weinstein TA; Sciubba JJ; Levine J Thalidomide for the treatment of oral aphthous ulcers in Crohn's disease | 10 | 21 |
1492 | 6 | 23 | 1572 1999 FEB [15] JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN 57(2):92-104 Shimazawa R; Takayama H; Hashimoto Y Development of novel biological response modifiers derived from thalidomide | 0 | 7 |
1493 | 10 | 18 | 1560 1999 FEB 19 JOURNAL OF CHROMATOGRAPHY B 723(1-2):255-264 Meyring M; Strickmann D; Chankvetadze B; Blaschke G; Desiderio C; Fanali S Investigation of the in vitro biotransformation of R-(+)- thalidomide by HPLC, nano-HPLC, CEC and HPLC-APCI-MS | 8 | 20 |
1494 | 30 | 79 | 1581 1999 MAR 10 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 425(1):153-167 Zhu XY; Zhang YP; Klopman G; Rosenkranz HS Thalidomide and metabolites: indications of the absence of 'genotoxic' carcinogenic potentials | 3 | 3 |
1495 | 0 | 0 | 1485 1999 MAR [15] AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 159(3):A271-A271 Lindsay L; Oliver S; Freeman S; Regis J; Krauss A; Kaplan G The role of thalidomide and steroid in modulating the expression of TNF-alpha (TNA-a) and IL-6 in the hyperoxic newborn rat lung. | 0 | 0 |
1496 | 3 | 8 | 1490 1999 MAR [15] ARTHRITIS AND RHEUMATISM 42(3):580-581 Breban M; Gombert B; Amor B; Dougados M Efficacy of thalidomide in the treatment of refractory ankylosing spondylitis | 16 | 53 |
1497 | 13 | 16 | 1525 1999 MAR [15] CLEVELAND CLINIC JOURNAL OF MEDICINE 66(3):136-+ Calabrese LH Thalidomide's tightly controlled "comeback" | 3 | 3 |
1498 | 0 | 0 | 1555 1999 MAR 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 40(4):S84-S84 Velez G; Robinson MR; Durbin T; Yuan P; Sung C; Whitcup SM Thalidomide-sustained release devices for choroidal neovascularization; An in-vitro analysis | 0 | 1 |
1499 | 0 | 0 | 1556 1999 MAR 15 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 40(4):S224-S224 Spraul CW; Kaven C; Amann J; Lang GK; Lang GE Effect of thalidomide, octreotide, and decortine on the migration and proliferation of RPE cells in vitro | 0 | 0 |
1500 | 4 | 13 | 1592 1999 MAR-APR [MAR 15] ORGANIC PROCESS RESEARCH & DEVELOPMENT 3(2):139-140 Muller GW; Konnecke WE; Smith AM; Khetani VD A concise two-step synthesis of thalidomide | 5 | 12 |
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