HistCite - JL Sussman papers

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#	Date / Author / Journal	LCS	GCS	LCR	CR
1	66 SUSSMAN JL, HAREL M, FROLOW F, OEFNER C, GOLDMAN A, et al. ATOMIC-STRUCTURE OF ACETYLCHOLINESTERASE FROM TORPEDO-CALIFORNICA - A PROTOTYPIC ACETYLCHOLINE-BINDING PROTEIN SCIENCE. 1991 AUG 23; 253 (5022): 872-879	80	1675	2	99
2	89 HAREL M, SCHALK I, EHRETSABATIER L, BOUET F, GOELDNER M, et al. QUATERNARY LIGAND-BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1993 OCT 1; 90 (19): 9031-9035	50	501	3	35
3	130 Raves ML, Harel M, Pang YP, Silman I, Kozikowski AP, et al. Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A NATURE STRUCTURAL BIOLOGY. 1997 JAN; 4 (1): 57-63	35	237	7	45
4	60 SUSSMAN JL, HAREL M, FROLOW F, VARON L, TOKER L, et al. PURIFICATION AND CRYSTALLIZATION OF A DIMERIC FORM OF ACETYLCHOLINESTERASE FROM TORPEDO-CALIFORNICA SUBSEQUENT TO SOLUBILIZATION WITH PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE-C JOURNAL OF MOLECULAR BIOLOGY. 1988 OCT 5; 203 (3): 821-822	31	72	0	20
5	106 Harel M, Kleywegt GJ, Ravelli RBG, Silman I, Sussman JL Crystal structure of an acetylcholinesterase-fasciculin complex: Interaction of a three-fingered toxin from snake venom with its target STRUCTURE. 1995 DEC 15; 3 (12): 1355-1366	27	160	11	70
6	115 Harel M, Quinn DM, Nair HK, Silman I, Sussman JL The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 1996 MAR 13; 118 (10): 2340-2346	27	221	6	79
7	161 Kryger G, Silman I, Sussman JL Structure of acetylcholinesterase complexed with E2020 (Aricept (R)): implications for the design of new anti-Alzheimer drugs STRUCTURE. 1999 MAR 15; 7 (3): 297-307	26	192	8	58
8	92 AXELSEN PH, HAREL M, SILMAN I, SUSSMAN JL STRUCTURE AND DYNAMICS OF THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE - SYNERGISTIC USE OF MOLECULAR-DYNAMICS SIMULATION AND X-RAY CRYSTALLOGRAPHY PROTEIN SCIENCE. 1994 FEB; 3 (2): 188-197	25	106	7	32
9	85 RIPOLL DR, FAERMAN CH, AXELSEN PH, SILMAN I, SUSSMAN JL AN ELECTROSTATIC MECHANISM FOR SUBSTRATE GUIDANCE DOWN THE AROMATIC GORGE OF ACETYLCHOLINESTERASE PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1993 JUN 1; 90 (11): 5128-5132	22	182	3	26
10	17 SUSSMAN JL, HOLBROOK SR, CHURCH GM, KIM SH STRUCTURE-FACTOR LEAST-SQUARES REFINEMENT PROCEDURE FOR MACROMOLECULAR STRUCTURES USING CONSTRAINED AND RESTRAINED PARAMETERS ACTA CRYSTALLOGRAPHICA SECTION A. 1977; 33 (SEP1): 800-804	20	328	2	26
#	Date / Author / Journal	LCS	GCS	LCR	CR
11	77 HAREL M, SUSSMAN JL, KREJCI E, BON S, CHANAL P, et al. CONVERSION OF ACETYLCHOLINESTERASE TO BUTYRYLCHOLINESTERASE - MODELING AND MUTAGENESIS PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1992 NOV 15; 89 (22): 10827-10831	18	236	1	37
12	73 OLLIS DL, CHEAH E, CYGLER M, DIJKSTRA B, FROLOW F, et al. THE ALPHA/BETA-HYDROLASE FOLD PROTEIN ENGINEERING. 1992 APR; 5 (3): 197-211	17	1143	1	52
13	93 GILSON MK, STRAATSMA TP, MCCAMMON JA, RIPOLL DR, FAERMAN CH, et al. OPEN BACK DOOR IN A MOLECULAR-DYNAMICS SIMULATION OF ACETYLCHOLINESTERASE SCIENCE. 1994 MAR 4; 263 (5151): 1276-1278	17	193	5	23
14	133 Felder CE, Botti SA, Lifson S, Silman I, Sussman JL External and internal electrostatic potentials of cholinesterase models JOURNAL OF MOLECULAR GRAPHICS & MODELLING. 1997 OCT; 15 (5): 318-+	16	48	5	36
15	169 Greenblatt HM, Kryger G, Lewis T, Silman I, Sussman JL Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 angstrom resolution FEBS LETTERS. 1999 DEC 17; 463 (3): 321-326	16	102	4	53
16	172 Koellner G, Kryger G, Millard CB, Silman I, Sussman JL, et al. Active-site gorge and buried water molecules in crystal structures of acetylcholinesterase from Torpedo californica JOURNAL OF MOLECULAR BIOLOGY. 2000 FEB 18; 296 (2): 713-735	13	73	17	66
17	179 Kryger G, Harel M, Giles K, Toker L, Velan B, et al. Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2000 NOV; 56: 1385-1394	13	130	13	51
18	164 Millard CB, Kryger G, Ordentlich A, Greenblatt HM, Harel M, et al. Crystal structures of aged phosphonylated acetylcholinesterase: Nerve agent reaction products at the atomic level BIOCHEMISTRY. 1999 JUN 1; 38 (22): 7032-7039	12	121	5	63
19	166 Millard CB, Koellner G, Ordentlich A, Shafferman A, Silman I, et al. Reaction products of acetylcholinesterase and VX reveal a mobile histidine in the catalytic triad JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 1999 OCT 27; 121 (42): 9883-9884	12	87	3	18
20	167 Botti SA, Felder CE, Lifson S, Sussman JL, Silman I A modular treatment of molecular traffic through the active site of cholinesterase BIOPHYSICAL JOURNAL. 1999 NOV; 77 (5): 2430-2450	12	31	9	105
#	Date / Author / Journal	LCS	GCS	LCR	CR
21	205 Zeev-Ben-Mordehai T, Rydberg EH, Solomon A, Toker L, Auld VJ, et al. The intracellular domain of the Drosophila cholinesterase-like neural adhesion protein, gliotactin, is natively unfolded PROTEINS-STRUCTURE FUNCTION AND GENETICS. 2003 NOV 15; 53 (3): 758-767	12	35	1	49
22	192 Bar-On P, Millard CB, Harel M, Dvir H, Enz A, et al. Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine BIOCHEMISTRY. 2002 MAR 19; 41 (11): 3555-3564	11	109	13	61
23	198 Greenblatt HM, Dvir H, Silman I, Sussman JL Acetylcholinesterase - A multifaceted target for structure-based drug design of anticholinesterase agents for the treatment of Alzheimer's disease JOURNAL OF MOLECULAR NEUROSCIENCE. 2003; 20 (3): 369-383	11	43	23	77
24	203 Dvir H, Harel M, McCarthy AA, Toker L, Silman I, et al. X-ray structure of human acid-beta-glucosidase, the defective enzyme in Gaucher disease EMBO REPORTS. 2003 JUL; 4 (7): 704-709	11	73	1	37
25	220 Silman I, Sussman JL Acetylcholinesterase: 'classical' and 'non-classical' functions and pharmacology CURRENT OPINION IN PHARMACOLOGY. 2005 JUN; 5 (3): 293-302	11	108	14	73
26	78 TAN RC, TRUONG TN, MCCAMMON JA, SUSSMAN JL ACETYLCHOLINESTERASE - ELECTROSTATIC STEERING INCREASES THE RATE OF LIGAND-BINDING BIOCHEMISTRY. 1993 JAN 19; 32 (2): 401-403	10	99	1	28
27	79 CYGLER M, SCHRAG JD, SUSSMAN JL, HAREL M, SILMAN I, et al. RELATIONSHIP BETWEEN SEQUENCE CONSERVATION AND 3-DIMENSIONAL STRUCTURE IN A LARGE FAMILY OF ESTERASES, LIPASES, AND RELATED PROTEINS PROTEIN SCIENCE. 1993 MAR; 2 (3): 366-382	10	361	2	72
28	175 Harel M, Kryger G, Rosenberry TL, Mallender WD, Lewis T, et al. Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors PROTEIN SCIENCE. 2000 JUN; 9 (6): 1063-1072	10	122	10	49
29	22 SUSSMAN JL, HOLBROOK SR, WARRANT RW, CHURCH GM, KIM SH CRYSTAL-STRUCTURE OF YEAST PHENYLALANINE TRANSFER-RNA .1. CRYSTALLOGRAPHIC REFINEMENT JOURNAL OF MOLECULAR BIOLOGY. 1978; 123 (4): 607-630	9	281	5	27
30	91 EICHLER J, ANSELMET A, SUSSMAN JL, MASSOULIE J, SILMAN I DIFFERENTIAL-EFFECTS OF PERIPHERAL SITE LIGANDS ON TORPEDO AND CHICKEN ACETYLCHOLINESTERASE MOLECULAR PHARMACOLOGY. 1994 FEB; 45 (2): 335-340	9	54	4	44
#	Date / Author / Journal	LCS	GCS	LCR	CR
31	9 KIM SH, SUDDATH FL, QUIGLEY GJ, MCPHERSO.A, SUSSMAN JL, et al. 3-DIMENSIONAL TERTIARY STRUCTURE OF YEAST PHENYLALANINE TRANSFER-RNA SCIENCE. 1974; 185 (4149): 435-440	8	719	0	12
32	121 Faerman C, Ripoll D, Bon S, LeFeuvre Y, Morel N, et al. Site-directed mutants designed to test back-door hypotheses of acetylcholinesterase function FEBS LETTERS. 1996 MAY 13; 386 (1): 65-71	8	47	9	41
33	170 Weik M, Ravelli RBG, Kryger G, McSweeney S, Raves ML, et al. Specific chemical and structural damage to proteins produced by synchrotron radiation PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000 JAN 18; 97 (2): 623-628	8	229	6	39
34	222 Premkumar L, Sawkar AR, Boldin-Adamsky S, Toker L, Silman I, et al. X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide - Implications for Gaucher disease. JOURNAL OF BIOLOGICAL CHEMISTRY. 2005 JUN 24; 280 (25): 23815-23819	8	41	2	28
35	3 SUSSMAN JL, SEEMAN NC, KIM SH, BERMAN HM CRYSTAL-STRUCTURE OF A NATURALLY OCCURRING DINUCLEOSIDE PHOSPHATE - URIDYLYL 3',5' ADENOSINE PHOSPHATE MODEL FOR RNA CHAIN FOLDING JOURNAL OF MOLECULAR BIOLOGY. 1972; 66 (3): 403-&	7	189	1	25
36	13 SUSSMAN JL, KIM SH IDEALIZED ATOMIC COORDINATES OF YEAST PHENYLALANINE TRANSFER-RNA BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1976; 68 (1): 89-96	7	94	1	8
37	101 PEITSCH MC, WELLS TNC, STAMPF DR, SUSSMAN JL THE SWISS-3DIMAGE COLLECTION AND PDB-BROWSER ON THE WORLDWIDE WEB TRENDS IN BIOCHEMICAL SCIENCES. 1995 FEB; 20 (2): 82-84	7	79	0	5
38	156 Botti SA, Felder CE, Sussman JL, Silman I Electrotactins: a class of adhesion proteins with conserved electrostatic and structural motifs PROTEIN ENGINEERING. 1998 JUN; 11 (6): 415-420	7	66	9	41
39	163 Morel N, Bon S, Greenblatt HM, Van Belle D, Wodak SJ, et al. Effect of mutations within the peripheral anionic site on the stability of acetylcholinesterase MOLECULAR PHARMACOLOGY. 1999 JUN; 55 (6): 982-992	7	18	8	39
40	204 Xu YC, Shen JH, Luo XM, Silman I, Sussman JL, et al. How does Huperzine A enter and leave the binding gorge of acetylcholinesterase? Steered molecular dynamics simulations JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2003 SEP 17; 125 (37): 11340-11349	7	35	10	57
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41	215 Greenblatt HM, Guillou C, Guenard D, Argaman A, Botti S, et al. The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: Implications for structure-based drug design JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2004 DEC 1; 126 (47): 15405-15411	7	38	18	63
42	232 Colletier JP, Fournier D, Greenblatt HM, Stojan J, Sussman JL, et al. Structural insights into substrate traffic and inhibition in acetylcholinesterase EMBO JOURNAL. 2006 JUN 21; 25 (12): 2746-2756	7	48	15	65
43	104 STAMPF DR, FELDER CE, SUSSMAN JL PDBBROWSE - A GRAPHICS INTERFACE TO THE BROOKHAVEN PROTEIN DATA-BANK NATURE. 1995 APR 6; 374 (6522): 572-574	6	25	2	6
44	191 Dvir H, Wong DM, Harel M, Barril X, Orozco M, et al. 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 angstrom resolution: Kinetic and molecular dynamic correlates BIOCHEMISTRY. 2002 MAR 5; 41 (9): 2970-2981	6	56	13	81
45	195 Felder CE, Harel M, Silman I, Sussman JL Structure of a complex of the potent and specific inhibitor BW284C51 with Torpedo californica acetylcholinesterase ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2002 OCT; 58: 1765-1771	6	29	10	41
46	199 Wong DM, Greenblatt HM, Dvir H, Carlier PR, Han YF, et al. Acetylcholinesterase complexed with bivalent ligands related to huperzine A: Experimental evidence for species-dependent protein-ligand complementarity JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2003 JAN 15; 125 (2): 363-373	6	48	17	66
47	209 Futerman AH, Sussman JL, Horowitz M, Silman I, Zimran A New directions in the treatment of Gaucher disease TRENDS IN PHARMACOLOGICAL SCIENCES. 2004 MAR; 25 (3): 147-151	6	42	1	27
48	224 Prilusky J, Felder CE, Zeev-Ben-Mordehai T, Rydberg EH, Man O, et al. FoldIndex((c)): a simple tool to predict whether a given protein sequence is intrinsically unfolded BIOINFORMATICS. 2005 AUG 15; 21 (16): 3435-3438	6	205	2	20
49	233 Rydberg EH, Brumshtein B, Greenblatt HM, Wong DM, Shaya D, et al. Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of bis(5)-tacrine produces a dramatic rearrangement in the active-site gorge JOURNAL OF MEDICINAL CHEMISTRY. 2006 SEP 7; 49 (18): 5491-5500	6	30	10	58
50	45 SAPER MA, ELDAR H, MIZUUCHI K, NICKOL J, APPELLA E, et al. CRYSTALLIZATION OF A DNA TRIDECAMER D(C-G-C-A-G-A-A-T-T-C-G-C-G) JOURNAL OF MOLECULAR BIOLOGY. 1986 MAR 5; 188 (1): 111-113	5	15	2	15
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51	61 UNGER R, HAREL D, WHERLAND S, SUSSMAN JL A 3D BUILDING-BLOCKS APPROACH TO ANALYZING AND PREDICTING STRUCTURE OF PROTEINS PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 1989; 5 (4): 355-373	5	153	0	18
52	178 Zhu WL, Tan XJ, Puah CM, Gu JD, Jiang HL, et al. How does ammonium interact with aromatic groups? A density functional theory (DFT/B3LYP) investigation JOURNAL OF PHYSICAL CHEMISTRY A. 2000 OCT 26; 104 (42): 9573-9580	5	47	6	39
53	210 Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, et al. Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2004 MAY; 11 (5): 412-419	5	183	1	38
54	240 Brumshtein B, Wormald MR, Silman I, Futerman AH, Sussman JL Structural comparison of differently glycosylated forms of acid-beta-glucosidase, the defective enzyme in Gaucher disease ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2006 DEC; 62: 1458-1465	5	16	2	35
55	248 Shaaltiel Y, Bartfeld D, Hashmueli S, Baum G, Brill-Almon E, et al. Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system PLANT BIOTECHNOLOGY JOURNAL. 2007 SEP; 5 (5): 579-590	5	37	4	50
56	8 KIM SH, SUSSMAN JL, SUDDATH FL, QUIGLEY GJ, MCPHERSON A, et al. GENERAL STRUCTURE OF TRANSFER-RNA MOLECULES PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1974; 71 (12): 4970-4974	4	245	1	18
57	58 JOSHUATOR L, RABINOVICH D, HOPE H, FROLOW F, APPELLA E, et al. THE 3-DIMENSIONAL STRUCTURE OF A DNA DUPLEX CONTAINING LOOPED-OUT BASES NATURE. 1988 JUL 7; 334 (6177): 82-84	4	88	5	23
58	67 HAREL M, SU CT, FROLOW F, ASHANI Y, SILMAN I, et al. REFINED CRYSTAL-STRUCTURES OF AGED AND NON-AGED ORGANOPHOSPHORYL CONJUGATES OF GAMMA-CHYMOTRYPSIN JOURNAL OF MOLECULAR BIOLOGY. 1991 OCT 5; 221 (3): 909-918	4	33	1	37
59	72 MASSOULIE J, SUSSMAN JL, DOCTOR BP, SOREQ H, VELAN B, et al. RECOMMENDATIONS FOR NOMENCLATURE IN CHOLINESTERASES MULTIDISCIPLINARY APPROACHES TO CHOLINESTERASE FUNCTIONS. 1992; : 285-288	4	74	0	0
60	75 SHAFFERMAN A, KRONMAN C, FLASHNER Y, LEITNER M, GROSFELD H, et al. MUTAGENESIS OF HUMAN ACETYLCHOLINESTERASE - IDENTIFICATION OF RESIDUES INVOLVED IN CATALYTIC ACTIVITY AND IN POLYPEPTIDE FOLDING JOURNAL OF BIOLOGICAL CHEMISTRY. 1992 SEP 5; 267 (25): 17640-17648	4	105	2	52
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61	119 Frolow F, Harel M, Sussman JL, Mevarech M, Shoham M Insights into protein adaptation to a saturated salt environment from the crystal structure of a halophilic 2Fe-2S ferredoxin NATURE STRUCTURAL BIOLOGY. 1996 MAY; 3 (5): 452-458	4	112	2	22
62	141 Kryger G, Giles K, Harel M, Toker L, Velan B, et al. 3D structure at 2.7A resolution of native and E202Q mutant human acetylcholinesterase complexed with fasciculin-II STRUCTURE AND FUNCTION OF CHOLINESTERASES AND RELATED PROTEINS. 1998; : 323-326	4	8	3	20
63	157 Sussman JL, Lin DW, Jiang JS, Manning NO, Prilusky J, et al. Protein Data Bank (PDB): Database of three-dimensional structural information of biological macromolecules ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 1998 NOV 1; 54: 1078-1084	4	198	5	13
64	174 Kraut D, Goff H, Pai RK, Hosea NA, Silman I, et al. Inactivation studies of acetylcholinesterase with phenylmethylsulfonyl fluoride MOLECULAR PHARMACOLOGY. 2000 JUN; 57 (6): 1243-1248	4	15	4	16
65	182 Felder C, Jiang HL, Zhu WL, Chen KX, Silman I, et al. Quantum/classical mechanical comparison of cation-pi interactions between tetramethylammonium and benzene JOURNAL OF PHYSICAL CHEMISTRY A. 2001 MAR 1; 105 (8): 1326-1333	4	47	7	50
66	194 Dvir H, Jiang HL, Wong DM, Harel M, Chetrit M, et al. X-ray structures of Torpedo californica acetylcholinesterase complexed with (+)-Huperzine A and (-)-huperzine B: Structural evidence for an active site rearrangement BIOCHEMISTRY. 2002 SEP 3; 41 (35): 10810-10818	4	40	9	52
67	237 Banci L, Bertini I, Cusack S, de Jong RN, Heinemann U, et al. First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2006 OCT; 62: 1208-1217	4	18	6	37
68	250 Colletier JP, Royant A, Specht A, Sanson B, Nachon F, et al. Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2007 NOV; 63: 1115-1128	4	14	19	75
69	1 SEEMAN NC, SUSSMAN JL, BERMAN HM, KIM SH NUCLEIC ACID CONFORMATION - CRYSTAL STRUCTURE OF A NATURALLY OCCURRING DINUCLEOSIDE PHOSPHATE (UPA) NATURE-NEW BIOLOGY. 1971; 233 (37): 90-&	3	65	0	15
70	23 HOLBROOK SR, SUSSMAN JL, WARRANT RW, KIM SH CRYSTAL-STRUCTURE OF YEAST PHENYLALANINE TRANSFER-RNA .2. STRUCTURAL FEATURES AND FUNCTIONAL IMPLICATIONS JOURNAL OF MOLECULAR BIOLOGY. 1978; 123 (4): 631-660	3	251	6	31
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71	24 SUSSMAN JL, TRIFONOV EN POSSIBILITY OF NONKINKED PACKING OF DNA IN CHROMATIN PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1978; 75 (1): 103-107	3	88	2	35
72	27 SHOHAM M, YONATH A, SUSSMAN JL, MOULT J, TRAUB W, et al. CRYSTAL-STRUCTURE OF DEMETALLIZED CONCANAVALIN-A - METAL-BINDING REGION JOURNAL OF MOLECULAR BIOLOGY. 1979; 131 (2): 137-155	3	47	3	46
73	49 ROY S, WEINSTEIN S, BORAH B, NICKOL J, APPELLA E, et al. MECHANISM OF OLIGONUCLEOTIDE LOOP FORMATION IN SOLUTION BIOCHEMISTRY. 1986 NOV 18; 25 (23): 7417-7423	3	47	0	13
74	95 SILMAN I, HAREL M, AXELSEN P, RAVES M, SUSSMAN JL 3-DIMENSIONAL STRUCTURES OF ACETYLCHOLINESTERASE AND OF ITS COMPLEXES WITH ANTICHOLINESTERASE AGENTS BIOCHEMICAL SOCIETY TRANSACTIONS. 1994 AUG; 22 (3): 745-749	3	28	7	34
75	102 DYM O, MEVARECH M, SUSSMAN JL STRUCTURAL FEATURES THAT STABILIZE HALOPHILIC MALATE-DEHYDROGENASE FROM AN ARCHAEBACTERIUM SCIENCE. 1995 MAR 3; 267 (5202): 1344-1346	3	144	1	31
76	117 Marchot P, Ravelli RBG, Raves ML, Bourne Y, Vellom DC, et al. Soluble monomeric acetylcholinesterase from mouse: Expression, purification, and crystallization in complex with fasciculin PROTEIN SCIENCE. 1996 APR; 5 (4): 672-679	3	50	3	35
77	124 Abola EE, Sussman JL, Prilusky J, Manning NO Protein data bank archives of three-dimensional macromolecular structures MACROMOLECULAR CRYSTALLOGRAPHY, PT B. 1997; 277: 556-571	3	169	0	18
78	131 Sussman JL Bridging the gap NATURE STRUCTURAL BIOLOGY. 1997 JUL; 4 (7): 517-517	3	4	3	10
79	155 Kryger G, Silman I, Sussman JL Three-dimensional structure of a complex of E2020 with acetylcholinesterase from Torpedo californica JOURNAL OF PHYSIOLOGY-PARIS. 1998 JUN-AUG; 92 (3-4): 191-194	3	62	5	23
80	158 Ravelli RBG, Raves ML, Ren Z, Bourgeois D, Roth M, et al. Static Laue diffraction studies on acetylcholinesterase ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 1998 NOV 1; 54: 1359-1366	3	26	9	40
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81	183 Weik M, Kryger G, Schreurs AMM, Bouma B, Silman I, et al. Solvent behaviour in flash-cooled protein crystals at cryogenic temperatures ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2001 APR; 57: 566-573	3	50	4	43
82	187 Weik M, Ravelli RBG, Silman I, Sussman JL, Gros P, et al. Specific protein dynamics near the solvent glass transition assayed by radiation-induced structural changes PROTEIN SCIENCE. 2001 OCT; 10 (10): 1953-1961	3	33	5	50
83	201 Premkumar L, Bageshwar UK, Gokhman I, Zamir A, Sussman JL An unusual halotolerant alpha-type carbonic anhydrase from the alga Dunaliella salina functionally expressed in Escherichia coli PROTEIN EXPRESSION AND PURIFICATION. 2003 MAR; 28 (1): 151-157	3	11	0	16
84	202 Premkumar L, Greenblatt HM, Bageshwar UK, Savchenko T, Gokhman I, et al. Identification, cDNA cloning, expression, crystallization and preliminary X-ray analysis of an exceptionally halotolerant carbonic anhydrase from Dunaliella salina ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2003 JUN; 59: 1084-1086	3	4	1	11
85	219 Prilusky J, Oueillet E, Ulryck N, Pajon A, Bernauer J, et al. HalX: an open-source LIMS (Laboratory Information Management System) for small- to large-scale laboratories ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2005 JUN; 61: 671-678	3	10	0	14
86	223 Haviv H, Wong DM, Greenblatt HM, Carlier PR, Pang YP, et al. Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2005 AUG 10; 127 (31): 11029-11036	3	24	10	53
87	229 Niu CY, Xu YC, Xu Y, Luo XM, Duan WH, et al. Dynamic mechanism of E2020 binding to acetylcholinesterase: A steered molecular dynamics simulation JOURNAL OF PHYSICAL CHEMISTRY B. 2005 DEC 15; 109 (49): 23730-23738	3	16	11	44
88	234 Aricescu AR, Assenberg R, Bill RM, Busso D, Chang VT, et al. Eukaryotic expression: developments for structural proteomics ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2006 OCT; 62: 1114-1124	3	32	3	59
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LCR

183 Weik M, Kryger G, Schreurs AMM, Bouma B, Silman I, et al.

Solvent behaviour in flash-cooled protein crystals at cryogenic temperatures

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2001 APR; 57: 566-573

187 Weik M, Ravelli RBG, Silman I, Sussman JL, Gros P, et al.

Specific protein dynamics near the solvent glass transition assayed by radiation-induced structural changes

PROTEIN SCIENCE. 2001 OCT; 10 (10): 1953-1961

201 Premkumar L, Bageshwar UK, Gokhman I, Zamir A, Sussman JL

An unusual halotolerant alpha-type carbonic anhydrase from the alga Dunaliella salina functionally expressed in Escherichia coli

PROTEIN EXPRESSION AND PURIFICATION. 2003 MAR; 28 (1): 151-157

202 Premkumar L, Greenblatt HM, Bageshwar UK, Savchenko T, Gokhman I, et al.

Identification, cDNA cloning, expression, crystallization and preliminary X-ray analysis of an exceptionally halotolerant carbonic anhydrase from Dunaliella salina

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2003 JUN; 59: 1084-1086

219 Prilusky J, Oueillet E, Ulryck N, Pajon A, Bernauer J, et al.

HalX: an open-source LIMS (Laboratory Information Management System) for small- to large-scale laboratories

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2005 JUN; 61: 671-678

223 Haviv H, Wong DM, Greenblatt HM, Carlier PR, Pang YP, et al.

Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2005 AUG 10; 127 (31): 11029-11036

229 Niu CY, Xu YC, Xu Y, Luo XM, Duan WH, et al.

Dynamic mechanism of E2020 binding to acetylcholinesterase: A steered molecular dynamics simulation

JOURNAL OF PHYSICAL CHEMISTRY B. 2005 DEC 15; 109 (49): 23730-23738

234 Aricescu AR, Assenberg R, Bill RM, Busso D, Chang VT, et al.

Eukaryotic expression: developments for structural proteomics

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2006 OCT; 62: 1114-1124

246 Hodis E, Schreiber G, Rother K, Sussman JL

eMovie: a storyboard-based tool for making molecular movies

TRENDS IN BIOCHEMICAL SCIENCES. 2007 MAY; 32 (5): 199-204

249 Brumshtein B, Greenblatt HM, Butters TD, Shaaltiel Y, Aviezer D, et al.

Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase - Insights into the mechanism of chemical chaperone action in Gaucher disease

JOURNAL OF BIOLOGICAL CHEMISTRY. 2007 SEP 28; 282 (39): 29052-29058

Date / Author / Journal

LCS

GCS

LCR

251 Hodis E, Prilusky J, Martz E, Silman I, Moult J, et al.

Proteopedia - a scientific 'wiki' bridging the rift between three-dimensional structure and function of biomacromolecules

GENOME BIOLOGY. 2008; 9 (8): Art. No. R121

254 Xu YC, Colletier JP, Jiang HL, Silman I, Sussman JL, et al.

Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design

PROTEIN SCIENCE. 2008 APR; 17 (4): 601-605

260 Xu YC, Colletier JP, Weik M, Jiang HL, Moult J, et al.

Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics

BIOPHYSICAL JOURNAL. 2008 SEP 1; 95 (5): 2500-2511

263 Kacher Y, Brumshtein B, Boldin-Adamsky S, Toker L, Shainskaya A, et al.

Acid beta-glucosidase: insights from structural analysis and relevance to Gaucher disease therapy

BIOLOGICAL CHEMISTRY. 2008 NOV; 389 (11): 1361-1369

12 QUIGLEY GJ, WANG AHJ, SEEMAN NC, SUDDATH FL, RICH A, et al.

HYDROGEN-BONDING IN YEAST PHENYLALANINE TRANSFER-RNA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1975; 72 (12): 4866-4870

113

18 HOLBROOK SR, SUSSMAN JL, WARRANT RW, CHURCH GM, KIM SH

RNA-LIGAND INTERACTIONS - (I)MAGNESIUM BINDING-SITES IN YEAST TRANSFER-RNAPHE

NUCLEIC ACIDS RESEARCH. 1977; 4 (8): 2811-2820

206

30 TRIFONOV EN, SUSSMAN JL

THE PITCH OF CHROMATIN DNA IS REFLECTED IN ITS NUCLEOTIDE-SEQUENCE

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES. 1980; 77 (7): 3816-3820

405

36 SUSSMAN JL, PODJARNY AD

THE USE OF A CONSTRAINED RESTRAINED LEAST-SQUARES PROCEDURE FOR THE LOW-RESOLUTION REFINEMENT OF A MACROMOLECULE, YEAST TRANSFER RNAMET

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE. 1983; 39 (AUG): 495-505

37 HERZBERG O, SUSSMAN JL

PROTEIN MODEL-BUILDING BY THE USE OF A CONSTRAINED-RESTRAINED LEAST-SQUARES PROCEDURE

JOURNAL OF APPLIED CRYSTALLOGRAPHY. 1983; 16 (FEB): 144-150

100

53 MILLER M, WLODAWER A, APPELLA E, SUSSMAN JL

CRYSTALLIZATION OF A DNA DUPLEX 15-MER CONTAINING UNPAIRED BASES - D(CGCGAAATTTACGCG)

JOURNAL OF MOLECULAR BIOLOGY. 1987 JUN 20; 195 (4): 967-968

JL Sussman papers Papers by JL Sussman	Historiographs	Glossary HistCite Guide About Grand Totals: LCS 977, GCS 15581, CR 8062 Collection span: 1971 - 2011
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