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Nodes: 4464,
Authors: 8653,
Journals: 638,
Outer References: 124402,
Words: 7994
Collection span: 1971 - 2005
View: Overview. Sorted by LCS.
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| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 301 | 12 | 35 | 1940 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(11):6185-6191 Mao QK; Fulmer P; Li WB; DeRose EF; Petering DH Different conformations and site selectivity of HO2-Co(III)-bleomycin A(2) and Co(III)-bleomycin A(2) bound to DNA oligomers | 33 | 36 |
| 302 | 4 | 90 | 2164 1997 CHEMISTRY & BIOLOGY 4(3):175-186 Banerjee R The Yin-Yang of cobalamin biochemistry | 33 | 67 |
| 303 | 24 | 66 | 2282 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(41):9603-9613 Lui SM; Vanderwall DE; Wu W; Tang XJ; Turner CJ; et al. Structural characterization of Co center dot bleomycin A2 brown: Free and bound to d(CCAGGCCTGG) | 33 | 33 |
| 304 | 16 | 84 | 2341 1997 SCIENCE 277(5334):1953-1956 Hoganson CW; Babcock GT A metalloradical mechanism for the generation of oxygen from water in photosynthesis | 33 | 214 |
| 305 | 18 | 31 | 2354 1997 TRENDS IN BIOCHEMICAL SCIENCES 22(3):81-85 Reichard P The evolution of ribonucleotide reduction | 33 | 51 |
| 306 | 6 | 29 | 2408 1998 BIOCHEMISTRY 37(34):11864-11872 Marsh ENG; Ballou DP Coupling of cobalt-carbon bond homolysis and hydrogen atom abstraction in adenosylcobalamin-dependent glutamate mutase | 33 | 47 |
| 307 | 1 | 24 | 134 1984 NUCLEIC ACIDS RESEARCH 12(3):1581-1592 UESUGI S; SHIDA T; IKEHARA M; KOBAYASHI Y; KYOGOKU Y IDENTIFICATION OF OLIGONUCLEOTIDE FRAGMENTS PRODUCED IN A STRAND SCISSION REACTION OF THE D(C-G-C-G-C-G) DUPLEX BY BLEOMYCIN | 32 | 35 |
| 308 | 2 | 32 | 198 1986 BIOCHEMISTRY 25(23):7401-7408 KUWABARA M; YOON C; GOYNE T; THEDERAHN T; SIGMAN DS NUCLEASE ACTIVITY OF 1,10-PHENANTHROLINE COPPER-ION - REACTION WITH CGCGAATTCGCG AND ITS COMPLEXES WITH NETROPSIN AND ECORI | 32 | 122 |
| 309 | 11 | 22 | 520 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86(5):1485-1489 MAO SS; JOHNSTON MI; BOLLINGER JM; STUBBE J MECHANISM-BASED INHIBITION OF A MUTANT ESCHERICHIA-COLI RIBONUCLEOTIDE REDUCTASE (CYSTEINE-225-]SERINE) BY ITS SUBSTRATE CDP | 32 | 32 |
| 310 | 7 | 17 | 1079 1993 BIOCHEMICAL SOCIETY TRANSACTIONS 21(3):731-734 KNAPPE J; ELBERT S; FREY M; WAGNER AFV PYRUVATE FORMATE-LYASE MECHANISM INVOLVING THE PROTEIN-BASED GLYCYL RADICAL | 32 | 57 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 311 | 13 | 25 | 1156 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(12):8383-8386 REICHARD P THE ANAEROBIC RIBONUCLEOTIDE REDUCTASE FROM ESCHERICHIA-COLI | 32 | 59 |
| 312 | 8 | 20 | 1501 1995 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH 34(13-14):1512-1514 LUBBEN M; MEETSMA A; WILKINSON EC; FERINGA B; QUE L NONHEME IRON CENTERS IN OXYGEN ACTIVATION - CHARACTERIZATION OF AN IRON(III) HYDROPEROXIDE INTERMEDIATE | 32 | 84 |
| 313 | 2 | 44 | 1888 1996 CHEMICAL SOCIETY REVIEWS 25(5):329-& Buckel W; Golding BT Glutamate and 2-methyleneglutarate mutase: From microbial curiosities to paradigms for coenzyme B-12-dependent enzymes | 32 | 45 |
| 314 | 24 | 59 | 2098 1997 BIOCHEMISTRY 36(10):2807-2816 Lehmann TE; Ming LJ; Rosen ME; Que L NMR studies of the paramagnetic complex Fe(II)-bleomycin | 32 | 40 |
| 315 | 6 | 27 | 2386 1998 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 49(3):258-266 Jossek R; Reichelt R; Steinbuchel A In vitro biosynthesis of poly(3-hydroxybutyric acid) by using purified poly(hydroxyalkanoic acid) synthase of Chromatium vinosum | 32 | 39 |
| 316 | 49 | 437 | 2455 1998 CHEMICAL REVIEWS 98(3):1109-1151 Burrows CJ; Muller JG Oxidative nucleobase modifications leading to strand scission | 32 | 413 |
| 317 | 104 | 337 | 3939 2003 CHEMICAL REVIEWS 103(6):2167-2201 Stubbe J; Nocera DG; Yee CS; Chang MCY Radical initiation in the class I ribonucleotide reductase: Long-range proton-coupled electron transfer? | 32 | 27 |
| 318 | 10 | 32 | 258 1987 INORGANIC CHEMISTRY 26(23):3835-3836 HEIMBROOK DC; CARR SA; MENTZER MA; LONG EC; HECHT SM MECHANISM OF OXYGENATION OF CIS-STILBENE BY IRON BLEOMYCIN | 31 | 42 |
| 319 | 8 | 32 | 687 1990 NUCLEIC ACIDS RESEARCH 18(22):6665-6672 AIMI J; QIU H; WILLIAMS J; ZALKIN H; DIXON JE DENOVO PURINE NUCLEOTIDE BIOSYNTHESIS - CLONING OF HUMAN AND AVIAN CDNAS ENCODING THE TRIFUNCTIONAL GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE-AMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE-GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE BY FUNCTIONAL COMPLEMENTATION IN ESCHERICHIA-COLI | 31 | 57 |
| 320 | 2 | 27 | 807 1991 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 113(15):5884-5886 CHEN XY; ROKITA SE; BURROWS CJ DNA MODIFICATION - INTRINSIC SELECTIVITY OF NICKEL(II) COMPLEXES | 31 | 78 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 321 | 2 | 30 | 924 1992 CANCER RESEARCH 52(3):533-539 HEINEMANN V; XU YZ; CHUBB S; SEN A; HERTEL LW; et al. CELLULAR ELIMINATION OF 2',2'-DIFLUORODEOXYCYTIDINE 5'-TRIPHOSPHATE - A MECHANISM OF SELF-POTENTIATION | 31 | 99 |
| 322 | 6 | 67 | 1051 1992 SCIENCE 258(5081):434-440 KUO CF; MCREE DE; FISHER CL; OHANDLEY SF; CUNNINGHAM RP; et al. ATOMIC-STRUCTURE OF THE DNA-REPAIR [4FE-4S] ENZYME ENDONUCLEASE-III | 31 | 178 |
| 323 | 14 | 34 | 1165 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(34):25909-25913 HOLMES CE; HECHT SM FE-CENTER-DOT-BLEOMYCIN CLEAVES A TRANSFER-RNA PRECURSOR AND ITS TRANSFER DNA ANALOG AT THE SAME MAJOR SITE | 31 | 40 |
| 324 | 27 | 53 | 1675 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(2):740-746 GALLI C; ATTA M; ANDERSSON KK; GRASLUND A; BRUDVIG GW VARIATIONS OF THE DIFERRIC EXCHANGE COUPLING IN THE R2-SUBUNIT OF RIBONUCLEOTIDE REDUCTASE FROM 4 SPECIES AS DETERMINED BY SATURATION - RECOVERY EPR SPECTROSCOPY | 31 | 38 |
| 325 | 17 | 32 | 2216 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272(39):24216-24223 Ollagnier S; Mulliez E; Schmidt PP; Eliasson R; Gaillard J; et al. Activation of the anaerobic ribonucleotide reductase from Escherichia coli - The essential role of the iron-sulfur center for S-adenosylmethionine reduction | 31 | 81 |
| 326 | 23 | 70 | 2221 1997 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 2(2):159-167 Kurtz DM Structural similarity and functional diversity in diiron-oxo proteins | 31 | 88 |
| 327 | 25 | 45 | 2393 1998 BIOCHEMISTRY 37(4):1124-1130 Parkin SE; Chen SX; Ley BA; Mangravite L; Edmondson DE; et al. Electron injection through a specific pathway determines the outcome of oxygen activation at the diiron cluster in the F208Y mutant of Escherichia coli ribonucleotide reductase protein R2 | 31 | 32 |
| 328 | 20 | 54 | 2771 1999 INORGANIC CHEMISTRY 38(12):2880-2889 Siegbahn PEM Theoretical model studies of the iron dimer complex of MMO and RNR | 31 | 75 |
| 329 | 16 | 86 | 179 1985 PHARMACOLOGY & THERAPEUTICS 30(3):301-329 ASHLEY GW; STUBBE J CURRENT IDEAS ON THE CHEMICAL MECHANISM OF RIBONUCLEOTIDE REDUCTASES | 30 | 30 |
| 330 | 7 | 24 | 362 1988 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 110(6):2008-2009 KRISHNAMOORTHY CR; VANDERWALL DE; KOZARICH JW; STUBBE J DEGRADATION OF DNA-RNA HYBRIDS BY BLEOMYCIN - EVIDENCE FOR DNA STRAND SPECIFICITY AND FOR POSSIBLE STRUCTURAL MODULATION OF CHEMICAL MECHANISM | 30 | 30 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 331 | 4 | 62 | 453 1989 INORGANIC CHEMISTRY 28(3):468-477 BROWN SJ; HUDSON SE; STEPHAN DW; MASCHARAK PK SYNTHESES, STRUCTURES, AND SPECTRAL PROPERTIES OF A SYNTHETIC ANALOG OF COPPER(II)-BLEOMYCIN AND AN INTERMEDIATE IN THE PROCESS OF ITS FORMATION | 30 | 41 |
| 332 | 18 | 38 | 964 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(18):12622-12626 KARLSSON M; SAHLIN M; SJOBERG BM ESCHERICHIA-COLI RIBONUCLEOTIDE REDUCTASE - RADICAL SUSCEPTIBILITY TO HYDROXYUREA IS DEPENDENT ON THE REGULATORY STATE OF THE ENZYME | 30 | 39 |
| 333 | 11 | 48 | 1101 1993 BIOCHEMISTRY 32(47):12749-12760 SALOWE S; BOLLINGER JM; ATOR M; STUBBE J; MCCRACKEN J; et al. ALTERNATIVE MODEL FOR MECHANISM-BASED INHIBITION OF ESCHERICHIA-COLI RIBONUCLEOTIDE REDUCTASE BY 2'-AZIDO-2'-DEOXYURIDINE 5'-DIPHOSPHATE | 30 | 30 |
| 334 | 13 | 36 | 1186 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(7):2996-2997 FARINAS E; TAN JD; BAIDYA N; MASCHARAK PK A DESIGNED SYNTHETIC ANALOG OF CO(III)-BLEOMYCIN WITH ENHANCED DNA-BINDING AND PHOTOCLEAVING ACTIVITY | 30 | 39 |
| 335 | 8 | 29 | 1209 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(22):10029-10035 WHITTAKER MM; CHUANG YY; WHITTAKER JW MODELS FOR THE REDOX-ACTIVE SITE IN GALACTOSE-OXIDASE | 30 | 65 |
| 336 | 4 | 25 | 1226 1993 NATURE 361(6409):276-278 ABERG A; NORDLUND P; EKLUND H UNUSUAL CLUSTERING OF CARBOXYL SIDE-CHAINS IN THE CORE OF IRON-FREE RIBONUCLEOTIDE REDUCTASE | 30 | 45 |
| 337 | 1 | 35 | 1377 1994 JOURNAL OF BACTERIOLOGY 176(14):4328-4337 PIEPERFURST U; MADKOUR MH; MAYER F; STEINBUCHEL A PURIFICATION AND CHARACTERIZATION OF A 14-KILODALTON PROTEIN THAT IS BOUND TO THE SURFACE OF POLYHYDROXYALKANOIC ACID GRANULES IN RHODOCOCCUS RUBER | 30 | 49 |
| 338 | 10 | 20 | 1645 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(6):2443-2446 SUN XY; ELIASSON R; PONTIS E; ANDERSSON J; BUIST G; et al. GENERATION OF THE GLYCYL RADICAL OF THE ANAEROBIC ESCHERICHIA-COLI RIBONUCLEOTIDE REDUCTASE REQUIRES A SPECIFIC ACTIVATING ENZYME | 30 | 61 |
| 339 | 3 | 38 | 1649 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(16):9295-9300 PADMAKUMAR R; BANERJEE R EVIDENCE FROM ELECTRON-PARAMAGNETIC-RESONANCE SPECTROSCOPY OF THE PARTICIPATION OF RADICAL INTERMEDIATES IN THE REACTION CATALYZED BY METHYLMALONYL-COENZYME-A MUTASE | 30 | 51 |
| 340 | 7 | 57 | 1697 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(24):6428-6433 POGOZELSKI WK; MCNEESE TJ; TULLIUS TD WHAT SPECIES IS RESPONSIBLE FOR STRAND SCISSION IN THE REACTION OF [FE(II)EDTA](2-) AND H2O2 WITH DNA | 30 | 70 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 341 | 4 | 55 | 2684 1999 BIOCHEMISTRY 38(2):826-837 Muh U; Sinskey AJ; Kirby DP; Lane WS; STUBBE J PHA synthase from Chromatium vinosum: Cysteine 149 is involved in covalent catalysis | 30 | 29 |
| 342 | 9 | 81 | 2985 2000 BIOCHEMISTRY 39(14):3927-3936 Jia Y; Kappock TJ; Frick T; Sinskey AJ; Stubbe J Lipases provide a new mechanistic model for polyhydroxybutyrate (PHB) synthases: Characterization of the functional residues in Chromatium vinosum PHB synthase | 30 | 29 |
| 343 | 57 | 132 | 3153 2000 JOURNAL OF NATURAL PRODUCTS 63(1):158-168 Hecht SM Bleomycin: New perspectives on the mechanism of action | 30 | 59 |
| 344 | 42 | 70 | 3209 2000 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 122(49):12195-12206 Baldwin J; Krebs C; Ley BA; Edmondson DE; Huynh BH; et al. Mechanism of rapid electron transfer during oxygen activation in the R2 subunit of Escherichia coli ribonucleotide reductase. 1. Evidence for a transient tryptophan radical | 30 | 34 |
| 345 | 3 | 19 | 55 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(10):4843-4846 STUBBE J; ACKLES D; SEGAL R; BLAKLEY RL ON THE MECHANISM OF RIBONUCLEOSIDE TRIPHOSPHATE REDUCTASE FROM LACTOBACILLUS-LEICHMANNII - EVIDENCE FOR 3' C-H BOND-CLEAVAGE | 29 | 29 |
| 346 | 12 | 103 | 291 1988 ACS SYMPOSIUM SERIES 372:152-178 QUE L; SCARROW RC ACTIVE-SITES OF BINUCLEAR IRON OXO PROTEINS | 29 | 69 |
| 347 | 2 | 38 | 321 1988 BIOCHIMICA ET BIOPHYSICA ACTA 952(2):220-229 PRINCE RC; GEORGE GN; SAVAS JC; CRAMER SP; PATEL RN SPECTROSCOPIC PROPERTIES OF THE HYDROXYLASE OF METHANE MONOOXYGENASE | 29 | 61 |
| 348 | 3 | 40 | 519 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86(4):1105-1109 HAWLEY RC; KIESSLING LL; SCHREIBER SL MODEL OF THE INTERACTIONS OF CALICHEMICIN-GAMMA-1 WITH A DNA FRAGMENT FROM PBR322 | 29 | 115 |
| 349 | 4 | 32 | 1058 1992 TRENDS IN BIOCHEMICAL SCIENCES 17(3):119-123 ELLEDGE SJ; ZHENG Z; ALLEN JB RIBONUCLEOTIDE REDUCTASE - REGULATION, REGULATION, REGULATION | 29 | 100 |
| 350 | 6 | 28 | 1166 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(35):26200-26205 NYHOLM S; MANN GJ; JOHANSSON AG; BERGERON RJ; GRASLUND A; et al. ROLE OF RIBONUCLEOTIDE REDUCTASE IN INHIBITION OF MAMMALIAN-CELL GROWTH BY POTENT IRON CHELATORS | 29 | 93 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 351 | 23 | 94 | 1429 1994 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 116(13):5619-5630 BOGER DL; HONDA T; DANG Q TOTAL SYNTHESIS OF BLEOMYCIN-A(2) AND RELATED AGENTS .2. SYNTHESIS OF (-)-PYRIMIDOBLAMIC ACID, EPI-(+)-PYRIMIDOBLAMIC ACID, (+)- DESACETAMIDOPYRIMIDOBLAMIC ACID, AND (-)-DESCARBOXAMIDOPYRIMIDOBLAMIC ACID | 29 | 41 |
| 352 | 22 | 92 | 1595 1995 COORDINATION CHEMISTRY REVIEWS 144:1-38 MANCHANDA R; BRUDVIG GW; CRABTREE RH HIGH-VALENT OXOMANGANESE CLUSTERS - STRUCTURAL AND MECHANISTIC WORK RELEVANT TO THE OXYGEN-EVOLVING CENTER IN PHOTOSYSTEM-II | 29 | 123 |
| 353 | 14 | 159 | 2086 1997 ANNUAL REVIEW OF BIOCHEMISTRY 66:269-313 Ludwig ML; Matthews RG Structure-based perspectives on B-12-dependent enzymes | 29 | 113 |
| 354 | 11 | 45 | 2331 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(1):53-58 Tauer A; Benner SA The B-12-dependent ribonucleotide reductase from the archaebacterium Thermoplasma acidophila: An evolutionary solution to the ribonucleotide reductase conundrum | 29 | 42 |
| 355 | 22 | 50 | 2526 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(33):21003-21008 Ekberg M; Potsch S; Sandin E; Thunnissen M; Nordlund P; et al. Preserved catalytic activity in an engineered ribonucleotide reductase R2 protein with a nonphysiological radical transfer pathway - The importance of hydrogen bond connections between the participating residues | 29 | 33 |
| 356 | 14 | 20 | 2566 1998 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 120(9):2190-2191 Valentine AM; Tavares P; Pereira AS; Davydov R; Krebs C; et al. Generation of a mixed-valent Fe(III)Fe(IV) form of intermediate Q in the reaction cycle of soluble methane monooxygenase, an analog of intermediate X in ribonucleotide reductase R2 assembly | 29 | 32 |
| 357 | 54 | 108 | 2588 1998 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 120(36):9139-9148 Boger DL; Ramsey TM; Cai H; Hoehn ST; STUBBE J A systematic evaluation of the bleomycin A(2) L-threonine side chain: Its role in preorganization of a compact conformation implicated in sequence-selective DNA cleavage | 29 | 27 |
| 358 | 33 | 48 | 2705 1999 BIOCHEMISTRY 38(38):12197-12204 Broadwater JA; Achim C; Munck E; Fox BG Mossbauer studies of the formation and reactivity of a quasi-stable peroxo intermediate of stearoyl-acyl carrier protein Delta(9)- desaturase | 29 | 43 |
| 359 | 34 | 47 | 3557 2001 TRENDS IN BIOCHEMICAL SCIENCES 26(2):93-99 Stubbe J; Ge J; Yee CS The evolution of ribonucleotide reduction revisited | 29 | 27 |
| 360 | 5 | 26 | 197 1986 BIOCHEMISTRY 25(21):6586-6592 AJMERA S; WU JC; WORTH L; RABOW LE; STUBBE J; et al. DNA-DEGRADATION BY BLEOMYCIN - EVIDENCE FOR 2'R-PROTON ABSTRACTION AND FOR C-O BOND-CLEAVAGE ACCOMPANYING BASE PROPENAL FORMATION | 28 | 28 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 361 | 8 | 67 | 312 1988 BIOCHEMISTRY 27(9):3164-3174 HERTZBERG RP; CARANFA MJ; HECHT SM DEGRADATION OF STRUCTURALLY MODIFIED DNAS BY BLEOMYCIN GROUP ANTIBIOTICS | 28 | 33 |
| 362 | 1 | 36 | 318 1988 BIOCHEMISTRY 27(19):7470-7479 ZHANG K; STERN EA; ELLIS F; SANDERSLOEHR J; SHIEMKE AK THE ACTIVE-SITE OF HEMERYTHRIN AS DETERMINED BY X-RAY ABSORPTION FINE-STRUCTURE | 28 | 63 |
| 363 | 12 | 40 | 353 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(33):17780-17784 LARSSON A; KARLSSON M; SAHLIN M; SJOBERG BM RADICAL FORMATION IN THE DIMERIC SMALL SUBUNIT OF RIBONUCLEOTIDE REDUCTASE REQUIRES ONLY ONE TYROSINE-122 | 28 | 33 |
| 364 | 1 | 29 | 522 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86(20):7672-7676 SUGIURA Y; UESAWA Y; TAKAHASHI Y; KUWAHARA J; GOLIK J; et al. NUCLEOTIDE-SPECIFIC CLEAVAGE AND MINOR-GROOVE INTERACTION OF DNA WITH ESPERAMICIN ANTITUMOR ANTIBIOTICS - (DNA-DRUG INTERACTION ECORI SITE DISTAMYCIN) | 28 | 87 |
| 365 | 2 | 22 | 605 1990 FEBS LETTERS 272(1-2):61-64 YANG FD; SPANEVELLO RA; CELIKER I; HIRSCHMANN R; RUBIN H; et al. THE CARBOXYL TERMINUS HEPTAPEPTIDE OF THE R2 SUBUNIT OF MAMMALIAN RIBONUCLEOTIDE REDUCTASE INHIBITS ENZYME-ACTIVITY AND CAN BE USED TO PURIFY THE R1 SUBUNIT | 28 | 37 |
| 366 | 14 | 54 | 619 1990 INORGANIC CHEMISTRY 29(26):5174-5183 WU FJ; KURTZ DM; HAGEN KS; NYMAN PD; DEBRUNNER PG; et al. (MU-OXO-HYDROXO)BIS(MU-CARBOXYLATO)DIIRON(III) AND DIMANGANESE(III) COMPLEXES WITH CAPPING TRIS(IMIDAZOL-2-YL)PHOSPHINE LIGANDS | 28 | 64 |
| 367 | 12 | 27 | 879 1992 BIOCHEMISTRY 31(3):780-786 GEREZ C; FONTECAYE M REDUCTION OF THE SMALL SUBUNIT OF ESCHERICHIA-COLI RIBONUCLEOTIDE REDUCTASE BY HYDRAZINES AND HYDROXYLAMINES | 28 | 35 |
| 368 | 7 | 33 | 1115 1993 BIOPHYSICAL JOURNAL 64(3):762-772 WHITTAKER MM; WHITTAKER JW LIGAND INTERACTIONS WITH GALACTOSE-OXIDASE - MECHANISTIC INSIGHTS | 28 | 82 |
| 369 | 15 | 28 | 1187 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(8):3350-3351 DUFF RJ; DEVROOM E; GELUK A; HECHT SM; VANDERMAREL GA; et al. EVIDENCE FOR C-1' HYDROGEN ABSTRACTION FROM MODIFIED OLIGONUCLEOTIDES BY FE.BLEOMYCIN | 28 | 38 |
| 370 | 8 | 17 | 1589 1995 CHEMISTRY & BIOLOGY 2(6):367-375 GIESE B; BEYRICHGRAF X; ERDMANN P; PETRETTA M; SCHWITTER U THE CHEMISTRY OF SINGLE-STRANDED 4'-DNA RADICALS - INFLUENCE OF THE RADICAL PRECURSOR ON ANAEROBIC AND AEROBIC STRAND CLEAVAGE | 28 | 60 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 371 | 23 | 57 | 1999 1996 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 118(34):8111-8120 Lendzian F; Sahlin M; MacMillan F; Bittl R; Fiege R; et al. Electronic structure of neutral tryptophan radicals in ribonucleotide reductase studied by EPR and ENDOR spectroscopy | 28 | 34 |
| 372 | 21 | 27 | 2287 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(51):12683-12684 Dong YH; Zang Y; Shu LJ; Wilkinson EC; Que L; et al. Models for nonheme diiron enzymes. Assembly of a high-valent Fe-2(mu-O)(2) diamond core from its peroxo precursor | 28 | 42 |
| 373 | 7 | 55 | 2395 1998 BIOCHEMISTRY 37(12):4105-4113 Bothe H; Darley DJ; Albracht SPJ; Gerfen GJ; Golding BT; et al. Identification of the 4-glutamyl radical as an intermediate in the carbon skeleton rearrangement catalyzed by coenzyme B-12-dependent glutamate mutase from Clostridium cochlearium | 28 | 44 |
| 374 | 4 | 29 | 2837 1999 JOURNAL OF MAGNETIC RESONANCE 138(2):232-243 Bennati M; Farrar CT; Bryant JA; Inati SJ; Weis V; et al. Pulsed electron-nuclear double resonance (ENDOR) at 140 GHz | 28 | 27 |
| 375 | 153 | 246 | 3540 2001 PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY 77(3):177-268 Eklund H; Uhlin U; Farnegardh M; Logan DT; Nordlund P Structure and function of the radical enzyme ribonucleotide reductase | 28 | 38 |
| 376 | 11 | 54 | 320 1988 BIOCHEMISTRY 27(20):7846-7852 PADBURY G; SLIGAR SG; LABEQUE R; MARNETT LJ FERRIC BLEOMYCIN CATALYZED REDUCTION OF 10-HYDROPEROXY-8,12-OCTADECADIENOIC ACID - EVIDENCE FOR HOMOLYTIC O-O BOND SCISSION | 27 | 33 |
| 377 | 4 | 23 | 395 1988 TRENDS IN BIOCHEMICAL SCIENCES 13(8):286-288 PRINCE RC TYROSINE RADICALS | 27 | 64 |
| 378 | 7 | 37 | 432 1989 BIOCHEMISTRY 28(18):7268-7275 BERNADOU J; PRATVIEL G; BENNIS F; GIRARDET M; MEUNIER B POTASSIUM MONOPERSULFATE AND A WATER-SOLUBLE MANGANESE PORPHYRIN COMPLEX, [MN(TMPYP)](OAC)5, AS AN EFFICIENT REAGENT FOR THE OXIDATIVE CLEAVAGE OF DNA | 27 | 115 |
| 379 | 9 | 37 | 474 1989 INORGANICA CHIMICA ACTA 165(1):123-129 BOSSEK U; WIEGHARDT K; NUBER B; WEISS J BIOINORGANIC MODEL COMPLEXES FOR THE ACTIVE-SITE IN MANGANESE CONTAINING CATALASES - THE CRYSTAL-STRUCTURES OF [L2MNII2(MU-OH)(MU-O2CCH3)2](PF6).CH3OH AND [L'2MNIII2(MU-O)(MU-O2CCH3)2](I3)I.H2O | 27 | 65 |
| 380 | 4 | 14 | 558 1990 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 168(2):659-664 FONTECAVE M; GEREZ C; ATTA M; JEUNET A HIGH VALENT IRON OXO INTERMEDIATES MIGHT BE INVOLVED DURING ACTIVATION OF RIBONUCLEOTIDE REDUCTASE - SINGLE OXYGEN ATOM DONORS GENERATE THE TYROSYL RADICAL | 27 | 37 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 381 | 1 | 195 | 682 1990 MUTATION RESEARCH 236(2-3):173-201 DOETSCH PW; CUNNINGHAM RP THE ENZYMOLOGY OF APURINIC APYRIMIDINIC ENDONUCLEASES | 27 | 228 |
| 382 | 12 | 63 | 768 1991 INORGANIC CHEMISTRY 30(8):1937-1943 BRENNAN BA; CHEN QH; JUAREZGARCIA C; TRUE AE; OCONNOR CJ; et al. MODELS FOR DIIRON OXO PROTEINS - THE PEROXIDE ADDUCT OF FE2(HPTB)(OH)(NO3)4 | 27 | 69 |
| 383 | 1 | 22 | 813 1991 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 113(19):7439-7440 MCCARTHY JR; MATTHEWS DP; STEMERICK DM; HUBER EW; BEY P; et al. STEREOSPECIFIC METHOD TO E-TERMINAL AND Z-TERMINAL FLUORO OLEFINS AND ITS APPLICATION TO THE SYNTHESIS OF 2'-DEOXY-2'-FLUOROMETHYLENE NUCLEOSIDES AS POTENTIAL INHIBITORS OF RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE | 27 | 107 |
| 384 | 10 | 26 | 970 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(35):25541-25547 ELIASSON R; PONTIS E; FONTECAVE M; GEREZ C; HARDER J; et al. CHARACTERIZATION OF COMPONENTS OF THE ANAEROBIC RIBONUCLEOTIDE REDUCTASE SYSTEM FROM ESCHERICHIA-COLI | 27 | 51 |
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| 392 | 8 | 46 | 242 1987 BIOCHEMISTRY 26(14):4242-4247 SJOBERG BM; SANDERSLOEHR J; LOEHR TM IDENTIFICATION OF A HYDROXIDE LIGAND AT THE IRON CENTER OF RIBONUCLEOTIDE REDUCTASE BY RESONANCE RAMAN-SPECTROSCOPY | 26 | 36 |
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| 395 | 7 | 40 | 890 1992 BIOCHEMISTRY 31(21):5022-5032 MEYER E; LEONARD NJ; BHAT B; STUBBE J; SMITH JM PURIFICATION AND CHARACTERIZATION OF THE PURE, PURK, AND PURC GENE-PRODUCTS - IDENTIFICATION OF A PREVIOUSLY UNRECOGNIZED ENERGY REQUIREMENT IN THE PURINE BIOSYNTHETIC-PATHWAY | 26 | 26 |
| 396 | 11 | 59 | 916 1992 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2(3):261-266 BOGER DL; MENEZES RF; DANG Q; YANG WJ DEGLYCO GABA,GLY-DESACETAMIDOBLEOMYCIN-A2 - A SIMPLIFIED SYNTHETIC MODEL FOR BLEOMYCIN-A2 | 26 | 31 |
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| 398 | 16 | 36 | 1086 1993 BIOCHEMISTRY 32(14):3617-3622 DEDON PC; SALZBERG AA; XU JH EXCLUSIVE PRODUCTION OF BISTRANDED DNA DAMAGE BY CALICHEAMICIN | 26 | 54 |
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| 410 | 10 | 35 | 849 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(8):3047-3051 MESCHWITZ SM; GOLDBERG IH SELECTIVE ABSTRACTION OF H-2 FROM C-5' OF THYMIDYLATE IN AN OLIGODEOXYNUCLEOTIDE BY THE RADICAL CENTER AT C-6 OF THE DIRADICAL SPECIES OF NEOCARZINOSTATIN - CHEMICAL EVIDENCE FOR THE STRUCTURE OF THE ACTIVATED DRUG DNA COMPLEX | 25 | 39 |
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| 411 | 7 | 21 | 971 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(35):25548-25552 HARDER J; ELIASSON R; PONTIS E; BALLINGER MD; REICHARD P ACTIVATION OF THE ANAEROBIC RIBONUCLEOTIDE REDUCTASE FROM ESCHERICHIA-COLI BY S-ADENOSYLMETHIONINE | 25 | 50 |
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| 415 | 11 | 35 | 1392 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(42):25978-25985 BURGER RM; DRLICA K; BIRDSALL B THE DNA CLEAVAGE PATHWAY OF IRON BLEOMYCIN - STRAND SCISSION PRECEDES DEOXYRIBOSE 3-PHOSPHATE BOND-CLEAVAGE | 25 | 30 |
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| 436 | 7 | 26 | 1041 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(9):3967-3971 PITIE M; PRATVIEL G; BERNADOU J; MEUNIER B PREFERENTIAL HYDROXYLATION BY THE CHEMICAL NUCLEASE MESO-TETRAKIS-(4-N-METHYLPYRIDINIUMYL)PORPHYRINATOMANGANESE(III) PENTAACETATE KHSO5 AT THE 5' CARBON OF DEOXYRIBOSES ON BOTH 3' SIDES OF 3 CONTIGUOUS A-BULLET-T BASE-PAIRS IN SHORT DOUBLE-STRANDED OLIGONUCLEOTIDES | 24 | 55 |
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| 475 | 3 | 52 | 525 1989 SCIENCE 245(4915):276-282 LATHAM JA; CECH TR DEFINING THE INSIDE AND OUTSIDE OF A CATALYTIC RNA MOLECULE | 22 | 278 |
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| 481 | 8 | 24 | 1180 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(2):798-800 BRANCHAUD BP; MONTAGUESMITH MP; KOSMAN DJ; MCLAREN FR MECHANISM-BASED INACTIVATION OF GALACTOSE-OXIDASE - EVIDENCE FOR A RADICAL MECHANISM | 22 | 42 |
| 482 | 7 | 27 | 1299 1994 BIOCHEMISTRY 33(10):2838-2842 LYCKSELL PO; INGEMARSON R; DAVIS R; GRASLUND A; THELANDER L H-1-NMR STUDIES OF MOUSE RIBONUCLEOTIDE REDUCTASE - THE R2 PROTEIN CARBOXYL-TERMINAL TAIL, ESSENTIAL FOR SUBUNIT INTERACTION, IS HIGHLY FLEXIBLE BUT BECOMES RIGID IN THE PRESENCE OF PROTEIN R1 | 22 | 31 |
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| 501 | 2 | 34 | 266 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(31):15144-15150 KELLER TJ; OPPENHEIMER NJ ENHANCED BLEOMYCIN-MEDIATED DAMAGE OF DNA OPPOSITE CHARGED NICKS - A MODEL FOR BLEOMYCIN-DIRECTED DOUBLE STRAND SCISSION OF DNA | 21 | 27 |
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| 504 | 9 | 41 | 419 1989 BIOCHEMICAL PHARMACOLOGY 38(1):133-140 PRATVIEL G; BERNADOU J; MEUNIER B EVIDENCE FOR HIGH-VALENT IRON-OXO SPECIES ACTIVE IN THE DNA BREAKS MEDIATED BY IRON-BLEOMYCIN | 21 | 30 |
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| 511 | 10 | 37 | 841 1991 NUCLEIC ACIDS RESEARCH 19(22):6283-6288 PRATVIEL G; PITIE M; BERNADOU J; MEUNIER B MECHANISM OF DNA CLEAVAGE BY CATIONIC MANGANESE PORPHYRINS - HYDROXYLATIONS AT THE 1'-CARBON AND 5'-CARBON ATOMS OF DEOXYRIBOSES AS INITIAL DAMAGES | 21 | 48 |
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| 541 | 4 | 74 | 850 1991 SCIENCE 252(5007):817-824 MCINTIRE WS; WEMMER DE; CHISTOSERDOV A; LIDSTROM ME A NEW COFACTOR IN A PROKARYOTIC ENZYME - TRYPTOPHAN TRYPTOPHYLQUINONE AS THE REDOX PROSTHETIC GROUP IN METHYLAMINE DEHYDROGENASE | 20 | 232 |
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| 575 | 2 | 57 | 521 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86(18):7054-7058 BENNER SA; ELLINGTON AD; TAUER A MODERN METABOLISM AS A PALIMPSEST OF THE RNA WORLD | 19 | 184 |
| 576 | 2 | 26 | 584 1990 BIOCHIMICA ET BIOPHYSICA ACTA 1020(3):305-310 KHANGULOV SV; BARYNIN VV; VOEVODSKAYA NV; GREBENKO AI ESR SPECTROSCOPY OF THE BINUCLEAR CLUSTER OF MANGANESE IONS IN THE ACTIVE-CENTER OF MN-CATALASE FROM THERMUS-THERMOPHILUS | 19 | 57 |
| 577 | 7 | 48 | 686 1990 NUCLEIC ACIDS RESEARCH 18(8):2093-2099 GALAT A; GOLDBERG IH MOLECULAR-MODELS OF NEOCARZINOSTATIN DAMAGE OF DNA - ANALYSIS OF SEQUENCE DEPENDENCE IN 5'-GAGCG-5'CGCTC | 19 | 31 |
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| 584 | 20 | 82 | 1520 1995 BIOCHEMISTRY 34(6):2015-2025 KHANGULOV SV; PESSIKI PJ; BARYNIN VV; ASH DE; DISMUKES GC DETERMINATION OF THE METAL-ION SEPARATION AND ENERGIES OF THE 3 LOWEST ELECTRONIC STATES OF DIMANGANESE(II,II) COMPLEXES AND ENZYMES - CATALASE AND LIVER ARGINASE | 19 | 73 |
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