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Nodes: 4464,
Authors: 8653,
Journals: 638,
Outer References: 124402,
Words: 7994
Collection span: 1971 - 2005
View: Overview. Sorted by LCR.
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| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 301 | 25 | 237 | 4252 2004 CHEMICAL REVIEWS 104(2):825-848 Kovacs JA Synthetic analogues of cysteinate-ligated non-heme iron and non-corrinoid cobalt enzymes | 1 | 4 |
| 302 | 25 | 77 | 4288 2004 EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (15):3118-3126 Papakyriakou A; Bratsos I; Katsarou M; Katsaros N Preparation, structure determination and cytotoxicity of the Pd-II center dot bleomycin A2 complex | 0 | 0 |
| 303 | 25 | 58 | 4303 2004 INORGANIC CHEMISTRY 43(2):613-621 Han WG; Lovell T; Liu TQ; Noodleman L Density functional study of a mu-1,1-carboxylate bridged Fe(III)-O-Fe(IV) model complex. 2. Comparison with ribonucleotide reductase intermediate X | 1 | 1 |
| 304 | 24 | 731 | 928 1992 CHEMICAL REVIEWS 92(6):1411-1456 MEUNIER B METALLOPORPHYRINS AS VERSATILE CATALYSTS FOR OXIDATION REACTIONS AND OXIDATIVE DNA CLEAVAGE | 38 | 904 |
| 305 | 24 | 73 | 989 1992 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 114(5):1681-1696 HOTZELMANN R; WIEGHARDT K; FLORKE U; HAUPT HJ; WEATHERBURN DC; et al. SPIN EXCHANGE COUPLING IN ASYMMETRIC HETERODINUCLEAR COMPLEXES CONTAINING THE MU-OXO-BIS(MU-ACETATO)DIMETAL CORE | 22 | 114 |
| 306 | 24 | 97 | 1007 1992 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 114(16):6278-6291 HAMAMICHI N; NATRAJAN A; HECHT SM ON THE ROLE OF INDIVIDUAL BLEOMYCIN THIAZOLES IN OXYGEN ACTIVATION AND DNA CLEAVAGE | 47 | 58 |
| 307 | 24 | 85 | 1017 1992 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 114(24):9470-9483 HOTZELMANN R; WIEGHARDT K; ENSLING J; ROMSTEDT H; GUTLICH P; et al. SYNTHESIS, CRYSTAL-STRUCTURES, MOSSBAUER, SUSCEPTIBILITY, AND EPR STUDIES OF A SERIES OF SPIN EXCHANGE COUPLED COMPLEXES CONTAINING THE (MU-OXO)BIS(MU-ACETATO)RUTHENIUMMETAL CORE AND ITS HYDROXO-BRIDGED ANALOG (METAL = V, CR, MN, FE, CO) | 5 | 35 |
| 308 | 24 | 46 | 1083 1993 BIOCHEMISTRY 32(10):2601-2609 WORTH L; FRANK BL; CHRISTNER DF; ABSALON MJ; STUBBE J; et al. ISOTOPE EFFECTS ON THE CLEAVAGE OF DNA BY BLEOMYCIN - MECHANISM AND MODULATION | 55 | 54 |
| 309 | 24 | 50 | 1248 1993 SCIENCE 260(5115):1773-1777 REICHARD P FROM RNA TO DNA, WHY SO MANY RIBONUCLEOTIDE REDUCTASES | 202 | 324 |
| 310 | 24 | 52 | 1818 1996 BIOCHEMISTRY 35(25):8381-8391 vanderDonk WA; Yu GX; Silva DJ; Stubbe J Inactivation of ribonucleotide reductase by (E)2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: A paradigm for nucleotide mechanism-based inhibitors | 35 | 34 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 311 | 24 | 55 | 1960 1996 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 1(4):297-304 Shu LJ; Liu Y; Lipscomb JD; Que L X-ray absorption spectroscopic studies of the methane monooxygenase hydroxylase component from Methylosinus trichosporium OB3b | 19 | 31 |
| 312 | 24 | 59 | 2098 1997 BIOCHEMISTRY 36(10):2807-2816 Lehmann TE; Ming LJ; Rosen ME; Que L NMR studies of the paramagnetic complex Fe(II)-bleomycin | 32 | 40 |
| 313 | 24 | 95 | 2258 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(12):2784-2794 Lenz R; Giese B Studies on the mechanism of ribonucleotide reductases | 37 | 43 |
| 314 | 24 | 58 | 2267 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(18):4197-4205 Zang Y; Kim J; Dong YH; Wilkinson EC; Appelman EH; et al. Models for nonheme iron intermediates: Structural basis for tuning the spin states of Fe(TPA) complexes | 21 | 91 |
| 315 | 24 | 66 | 2282 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(41):9603-9613 Lui SM; Vanderwall DE; Wu W; Tang XJ; Turner CJ; et al. Structural characterization of Co center dot bleomycin A2 brown: Free and bound to d(CCAGGCCTGG) | 33 | 33 |
| 316 | 24 | 48 | 2316 1997 NUCLEIC ACIDS RESEARCH 25(9):1836-1845 Bansal M; Lee JS; Stubbe J; Kozarich JW Mechanistic analyses of site-specific degradation in DNA-RNA hybrids by prototypic DNA cleavers | 7 | 7 |
| 317 | 24 | 41 | 2347 1997 TETRAHEDRON 53(35):12005-12016 Ashley GW; Lawrence CC; Stubbe J; Robins MJ Mechanism based inactivation of the adenosylcobalamin-dependent ribonucleotide reductase from L-leichmannii by 2'-ara-2'-azido-2'-deoxy adenosine-5'-triphosphate: Observation of paramagnetic intermediates | 2 | 2 |
| 318 | 24 | 297 | 2424 1998 BIOCONJUGATE CHEMISTRY 9(5):513-538 Bailly C; Chaires JB Sequence-specific DNA minor groove binders. Design and synthesis of netropsin and distamycin analogues | 2 | 115 |
| 319 | 24 | 58 | 2433 1998 BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 71(5):1159-1169 Arai T; Shinozuka K; Sawai H Distal effect of amide and amino groups on the oxygen activation ability and rate of the redox reaction of simplified analogs of bleomycin | 0 | 0 |
| 320 | 24 | 45 | 2524 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(26):16090-16097 Sam JW; Takahashi S; Lippai I; Peisach J; Rousseau DL Sequence-specific changes in the metal site of ferric bleomycin induced by the binding of DNA | 17 | 21 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 321 | 24 | 49 | 2538 1998 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 3(6):620-626 Dobbing AM; Han JY; Sykes AG Mechanism of dithionite reduction of the R2 protein of E-coli and mouse ribonucleotide reductase: evidence for reduction of Fe-2(III) prior to the tyrosyl radical | 2 | 3 |
| 322 | 24 | 40 | 2600 1998 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 120(49):12910-12919 Burdi D; Willems JP; Riggs-Gelasco P; Antholine WE; Stubbe J; et al. The core structure of X generated in the assembly of the diiron cluster of ribonucleotide reductase: O-17(2) and (H2O)-O-17 ENDOR | 45 | 45 |
| 323 | 24 | 62 | 2604 1998 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 120(51):13370-13382 Menage S; Galey JB; Dumats J; Hussler G; Seite M; et al. O-2 activation and aromatic hydroxylation performed by diiron complexes | 4 | 27 |
| 324 | 24 | 63 | 2880 1999 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 121(39):9023-9033 Aso M; Kondo M; Suemune H; Hecht SM Chemistry of the bleomycin-induced alkali-labile DNA lesion | 11 | 14 |
| 325 | 24 | 63 | 3055 2000 CHEMISTRY-A EUROPEAN JOURNAL 6(12):2152-2159 Roelfes G; Lubben M; Hage R; Que L; Feringa BL Catalytic oxidation with a non-heme iron complex that generates a low-spin (FeOOH)-O-III intermediate | 11 | 32 |
| 326 | 24 | 40 | 3141 2000 JOURNAL OF INORGANIC BIOCHEMISTRY 79(1-4):59-65 Twitchett MB; Dobbing AM; Sykes AG New mechanistic insights into the reactivity of the R2 protein of E-coli ribonucleotide reductase (RNR) | 2 | 2 |
| 327 | 24 | 45 | 3358 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(5):499-505 Marsh ENG; Drennan CL Adenosylcobalamin-dependent isomerases: new insights into structure and mechanism | 14 | 20 |
| 328 | 24 | 42 | 3427 2001 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 6(3):315-323 Hogbom M; Andersson ME; Nordlund P Crystal structures of oxidized dinuclear manganese centres in Mn-substituted class I ribonucleotide reductase from Escherichia coli: carboxylate shifts with implications for O-2 activation and radical generation | 11 | 16 |
| 329 | 24 | 57 | 3430 2001 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 6(7):717-725 Jin Y; Lipscomb JD Desaturation reactions catalyzed by soluble methane monooxygenase | 2 | 16 |
| 330 | 24 | 113 | 3487 2001 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 123(34):8271-8290 Lehnert N; Ho RYN; Que L; Solomon EI Spectroscopic properties and electronic structure of low-spin Fe(III)- alkylperoxo complexes: Homolytic cleavage of the O-O bond | 12 | 30 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 331 | 24 | 47 | 3743 2002 JOURNAL OF INORGANIC BIOCHEMISTRY 91(1):259-268 Zhao CQ; Xia CW; Mao QK; Forsterling H; DeRose E; et al. Structures of HO2-Co(III)bleomycin A(2) bound to d(GAGCTC)(2) and d(GGAAGCTTCC)(2): structure-reactivity relationships of Co and Fe bleomycins | 5 | 4 |
| 332 | 24 | 77 | 3982 2003 INORGANIC CHEMISTRY 42(3):750-760 Dubois L; Xiang DF; Tan XS; Pecaut J; Jones P; et al. Binuclear manganese compounds of potential biological significance. 1. Syntheses and structural, magnetic, and electrochemical properties of dimanganese(II) and -(II,III) complexes of a bridging unsymmetrical phenolate ligand | 1 | 9 |
| 333 | 24 | 119 | 3989 2003 INORGANIC CHEMISTRY 42(26):8652-8662 Kuzelka J; Farrell JR; Lippard SJ Modeling the syn disposition of nitrogen donors at the active sites of carboxylate-bridged diiron enzymes. Enforcing dinuclearity and kinetic stability with a 1,2-diethynylbenzene-based ligand | 0 | 2 |
| 334 | 24 | 409 | 4098 2003 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 531(1-2):37-80 Bjelland S; Seeberg E Mutagenicity, toxicity and repair of DNA base damage induced by oxidation | 0 | 4 |
| 335 | 24 | 252 | 4256 2004 CHEMICAL REVIEWS 104(3):1231-1253 Improta R; Barone V Interplay of electronic, environmental, and vibrational effects in determining the hyperfine coupling constants of organic free radicals | 1 | 10 |
| 336 | 24 | 77 | 4331 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(12):10919-10930 Schunemann V; Lendzian F; Jung C; Contzen J; Barra AL; et al. Tyrosine radical formation in the reaction of wild type and mutant cytochrome P450cam with peroxy acids - A multifrequency EPR study of intermediates on the millisecond time scale | 0 | 0 |
| 337 | 24 | 42 | 4353 2004 JOURNAL OF COMPUTATIONAL CHEMISTRY 25(10):1286-1294 Pereira S; Fernandes PA; Ramos MJ Mechanism for ribonucleotide reductase inactivation by the anticancer drug gemcitabine | 1 | 0 |
| 338 | 24 | 33 | 4455 2004 SCIENCE 305(5681):245-248 Hogbom M; Stenmark P; Voevodskaya N; McClarty G; Graslund A; et al. The radical site in chlamydial ribonucleotide reductase defines a new R2 subclass | 0 | 0 |
| 339 | 24 | 132 | 4458 2004 SOUTH AFRICAN JOURNAL OF SCIENCE 100(7-8):368-380 Perry CB; Marques HM Fifty years of X-ray crystallography of vitamin B-12 and its derivatives | 0 | 0 |
| 340 | 23 | 119 | 801 1991 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 113(1):152-164 TOLMAN WB; LIU SC; BENTSEN JG; LIPPARD SJ MODELS OF THE REDUCED FORMS OF POLYIRON-OXO PROTEINS - AN ASYMMETRIC, TRIPLY CARBOXYLATE BRIDGED DIIRON(II) COMPLEX AND ITS REACTION WITH DIOXYGEN | 46 | 129 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 341 | 23 | 107 | 1230 1993 PHOTOCHEMISTRY AND PHOTOBIOLOGY 57(1):179-188 BARRY BA THE ROLE OF REDOX-ACTIVE AMINO-ACIDS IN THE PHOTOSYNTHETIC WATER-OXIDIZING COMPLEX | 20 | 51 |
| 342 | 23 | 141 | 1261 1993 USPEKHI KHIMII 62(1):70-91 KNORRE DG; FEDOROVA OS; FROLOVA EI OXIDATIVE-DEGRADATION OF NUCLEIC-ACIDS | 4 | 9 |
| 343 | 23 | 94 | 1429 1994 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 116(13):5619-5630 BOGER DL; HONDA T; DANG Q TOTAL SYNTHESIS OF BLEOMYCIN-A(2) AND RELATED AGENTS .2. SYNTHESIS OF (-)-PYRIMIDOBLAMIC ACID, EPI-(+)-PYRIMIDOBLAMIC ACID, (+)- DESACETAMIDOPYRIMIDOBLAMIC ACID, AND (-)-DESCARBOXAMIDOPYRIMIDOBLAMIC ACID | 29 | 41 |
| 344 | 23 | 102 | 1449 1994 JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS (4):551-556 TUETING JL; SPENCE KL; ZIMMER M BINDING GEOMETRY OF COBALT BLEOMYCIN, AN EMPIRICAL FORCE-FIELD ANALYSIS | 5 | 12 |
| 345 | 23 | 35 | 1522 1995 BIOCHEMISTRY 34(6):2076-2086 ABSALON MJ; WU W; KOZARICH JW; STUBBE J SEQUENCE-SPECIFIC DOUBLE-STRAND CLEAVAGE OF DNA BY FE BLEOMYCIN .2. MECHANISM AND DYNAMICS | 76 | 75 |
| 346 | 23 | 53 | 1551 1995 BIOCHEMISTRY 34(43):14093-14103 SILVA KE; ELGREN TE; QUE L; STANKOVICH MT ELECTRON-TRANSFER PROPERTIES OF THE R2 PROTEIN OF RIBONUCLEOTIDE REDUCTASE FROM ESCHERICHIA-COLI | 21 | 30 |
| 347 | 23 | 36 | 1559 1995 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1264(3):323-329 Behravan G; Sen S; Rova U; Thelander L; Eckstein F; et al. Formation of a free radical of the sulfenylimine type in the mouse ribonucleotide reductase reaction with 2'-azido-2'-deoxycytidine 5'- diphosphate | 12 | 12 |
| 348 | 23 | 43 | 1648 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(12):6570-6576 ORMO M; REGNSTROM K; WANG ZG; QUE L; SAHLIN M; et al. RESIDUES IMPORTANT FOR RADICAL STABILITY IN RIBONUCLEOTIDE REDUCTASE FROM ESCHERICHIA-COLI | 34 | 41 |
| 349 | 23 | 94 | 1683 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(10):2778-2792 DONG YH; FUJII H; HENDRICH MP; LEISING RA; PAN GF; et al. A HIGH-VALENT NONHEME IRON INTERMEDIATE - STRUCTURE AND PROPERTIES OF [FE-2(MU-O)(2)(5-ME-TPA)(2)](CLO4)(3) | 52 | 129 |
| 350 | 23 | 71 | 1686 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(11):2970-2980 CHENG CC; GOLL JG; NEYHART GA; WELCH TW; SINGH P; et al. RELATIVE RATES AND POTENTIALS OF COMPETING REDOX PROCESSES DURING DNA CLEAVAGE - OXIDATION MECHANISMS AND SEQUENCE-SPECIFIC CATALYSIS OF THE SELF-INACTIVATION OF OXOMETAL OXIDANTS BY DNA | 34 | 70 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 351 | 23 | 54 | 1731 1995 MECHANISTIC BIOINORGANIC CHEMISTRY 246:61-81 Goldberg DP; Lippard SJ Modeling phenoxyl radical metalloenzyme active sites | 5 | 9 |
| 352 | 23 | 55 | 1861 1996 BULLETIN OF THE KOREAN CHEMICAL SOCIETY 17(12):1127-1131 Kim E; Lee KB; Jang HG Dioxygen binding to the singly alkoxo-bridged diferrous complex: Properties of [Fe-2(II)(N-Et-HPTB)Cl-2]BPh(4) | 1 | 1 |
| 353 | 23 | 44 | 1951 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(34):20770-20775 Young P; Andersson J; Sahlin M; Sjoberg BM Bacteriophage T4 anaerobic ribonucleotide reductase contains a stable glycyl radical at position 580 | 24 | 33 |
| 354 | 23 | 66 | 1969 1996 JOURNAL OF MOLECULAR BIOLOGY 262(5):706-720 Kauppi B; Nielsen BA; Ramaswamy S; Larsen IK; Thelander M; et al. The three-dimensional structure of mammalian ribonucleotide reductase protein R2 reveals a more-accessible iron-radical site than Escherichia coli R2 | 61 | 82 |
| 355 | 23 | 57 | 1999 1996 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 118(34):8111-8120 Lendzian F; Sahlin M; MacMillan F; Bittl R; Fiege R; et al. Electronic structure of neutral tryptophan radicals in ribonucleotide reductase studied by EPR and ENDOR spectroscopy | 28 | 34 |
| 356 | 23 | 85 | 2079 1997 ACCOUNTS OF CHEMICAL RESEARCH 30(6):227-237 Tolman WB Making and breaking the dioxygen O-O bond: New insights from studies of synthetic copper complexes | 9 | 219 |
| 357 | 23 | 70 | 2221 1997 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 2(2):159-167 Kurtz DM Structural similarity and functional diversity in diiron-oxo proteins | 31 | 88 |
| 358 | 23 | 73 | 2277 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(35):8217-8227 Halfen; JA; Jazdzewski BA; Mahapatra S; Berreau LM; et al. Synthetic models of the inactive copper(II)-tyrosinate and active copper(II)-tyrosyl radical forms of galactose and glyoxal oxidases | 0 | 93 |
| 359 | 23 | 73 | 2278 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(35):8217-8227 Halfen JA; Jazdzewski BA; Mahapatra S; Berreau LM; Wilkinson EC; et al. Synthetic models of the inactive copper(II)-tyrosinate and active copper(II)-tyrosyl radical forms of galactose and glyoxal oxidases | 39 | 92 |
| 360 | 23 | 64 | 2334 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(13):6959-6964 Hofer A; Schmidt PP; Graslund A; Thelander L Cloning and characterization of the R1 and R2 subunits of ribonucleotide reductase from Trypanosoma brucei | 10 | 20 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 361 | 23 | 31 | 2388 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 246(3):740-745 Liu A; Sahlin M; Potsch S; Sjoberg BM; Graslund A New paramagnetic species formed at the expense of the transient tyrosyl radical in mutant protein R2 F208Y of Escherichia coli ribonucleotide reductase | 3 | 4 |
| 362 | 23 | 38 | 2414 1998 BIOCHEMISTRY 37(42):14659-14663 Moenne-Loccoz P; Baldwin J; Ley BA; Loehr TM; Bollinger JM O-2 activation by non-heme diiron proteins: Identification of a symmetric mu-1,2-peroxide in a mutant of ribonucleotide reductase | 47 | 70 |
| 363 | 23 | 31 | 2564 1998 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 120(5):1094-1095 Bollinger JM; Krebs C; Vicol A; Chen SX; Ley BA; et al. Engineering the diiron site of Escherichia coli ribonucleotide reductase protein R2 to accumulate an intermediate similar to H-peroxo, the putative peroxodiiron(III) complex from the methane monooxygenase catalytic cycle | 51 | 60 |
| 364 | 23 | 35 | 2627 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(6):2723-2724 Stubbe J Ribonucleotide reductases in the twenty-first century | 25 | 25 |
| 365 | 23 | 122 | 2700 1999 BIOCHEMISTRY 38(29):9495-9507 Tommos C; Skalicky JJ; Pilloud DL; Wand AJ; Dutton PL De novo proteins as models of radical enzymes | 16 | 41 |
| 366 | 23 | 68 | 2867 1999 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 121(12):2770-2783 Yang YS; Broadwater JA; Pulver SC; Fox BG; Solomon EI Circular dichroism and magnetic circular dichroism studies of the reduced binuclear non-heme iron site of stearoyl-ACP Delta(9)- desaturase: Substrate binding and comparison to ribonucleotide reductase | 24 | 35 |
| 367 | 23 | 45 | 3002 2000 BIOCHEMISTRY 39(34):10507-10513 Lyle KS; Moenne-Loccoz P; Ai JY; Sanders-Loehr J; Loehr TM; et al. Resonance Raman studies of the stoichiometric catalytic turnover of a substrate-stearoyl-acyl carrier protein Delta(9) desaturase complex | 5 | 7 |
| 368 | 23 | 47 | 3179 2000 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 122(10):2206-2212 Dobbing AM; Borman CD; Twitchett MB; Leese DN; Salmon GA; et al. Mechanistic implications of a linear free-energy correlation of rate constants for the reduction of active-and met-R2 forms of E-coli ribonucleotide reductase with eight organic radicals | 2 | 4 |
| 369 | 23 | 71 | 3217 2000 METAL IONS IN BIOLOGICAL SYSTEMS, VOL 37 37:527-557 Yoder DW; Hwang J; Penner-Hahn JE Manganese catalases | 1 | 7 |
| 370 | 23 | 332 | 3229 2000 NATURAL PRODUCT REPORTS 17(4):367-383 Prescott AG; Lloyd MD The iron(II) and 2-oxoacid-dependent dioxygenases and their role in metabolism | 16 | 65 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 371 | 23 | 47 | 3344 2001 CHEMICAL RESEARCH IN TOXICOLOGY 14(5):528-535 Lopez-Larraza DM; Moore K; Dedon PC Thiols alter the partitioning of calicheamicin-induced deoxyribose 4 '- oxidation reactions in the absence of DNA radical repair | 1 | 2 |
| 372 | 23 | 33 | 3459 2001 JOURNAL OF PHYSICAL CHEMISTRY B 105(1):322-327 Torrent M; Musaev DG; Morokuma K The flexibility of carboxylate ligands in methane monooxygenase and ribonucleotide reductase: A density functional study | 10 | 20 |
| 373 | 23 | 85 | 3482 2001 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 123(26):6327-6337 Chen K; Que L Stereospecific alkane hydroxylation by non-heme iron catalysts: Mechanistic evidence for an Fe-V = O active species | 6 | 52 |
| 374 | 23 | 36 | 3695 2002 INORGANICA CHIMICA ACTA 331:65-72 Davydov A; Ohrstrom M; Liu AM; Thelander L; Graslund A Chemical reduction of the diferric/radical center in protein R2 from mouse ribonucleotide reductase is independent of the proposed radical transfer pathway | 0 | 0 |
| 375 | 23 | 79 | 3789 2002 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 124(38):11531-11540 Langella E; Improta R; Barone V Conformational and spectroscopic analysis of the tyrosyl radical dipeptide analogue in the gas phase and in aqueous solution by a density functional/continuum solvent model | 3 | 8 |
| 376 | 23 | 241 | 3881 2003 APPLIED BIOCHEMISTRY AND MICROBIOLOGY 39(2):115-139 Ryzhkova EP Multiple functions of corrinoids in prokaryote biology | 0 | 0 |
| 377 | 23 | 49 | 3985 2003 INORGANIC CHEMISTRY 42(8):2751-2758 Han WG; Lovell T; Liu TQ; Noodleman L A density functional evaluation of an Fe(III)-Fe(IV) model dilron cluster: Comparisons with ribonucleotide reductase intermediate X | 3 | 5 |
| 378 | 23 | 63 | 4037 2003 JOURNAL OF PHYSICAL CHEMISTRY B 107(1):331-337 Kaupp M; Gress T; Reviakine R; Malkina OL; Malkin VG g tensor and spin density of the modified tyrosyl radical in galactose oxidase: A density functional study | 1 | 2 |
| 379 | 23 | 65 | 4118 2003 PHYSICAL CHEMISTRY CHEMICAL PHYSICS 5(11):2442-2453 Lassmann G; Kolberg M; Bleifuss G; Graslund A; Sjoberg BM; et al. Protein thiyl radicals in disordered systems: A comparative EPR study at low temperature | 3 | 4 |
| 380 | 23 | 47 | 4272 2004 CURRENT OPINION IN CHEMICAL BIOLOGY 8(5):477-483 Reed GH Radical mechanisms in adenosylcobalamin-dependent enzymes | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 381 | 23 | 71 | 4385 2004 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 126(7):2237-2246 van Gastel M; Lubitz W; Lassmann G; Neese F Electronic structure of the cysteine thiyl radical: A DFT and correlated ab initio study | 0 | 2 |
| 382 | 22 | 81 | 617 1990 INORGANIC CHEMISTRY 29(20):4027-4032 BHULA R; COLLIER S; ROBINSON WT; WEATHERBURN DC COMPLEXES OF THE LIGAND 1,5,8,12-TETRAAZADODECANE (3,2,3-TET) WITH MANGANESE(III) AND WITH A VALENCE-TRAPPED MANGANESE(III) MANGANESE(IV) HEXANUCLEAR ARRAY - CRYSTAL AND MOLECULAR-STRUCTURES OF [TRANS-MN(3-IOBZ)2(3,2,3-TET)](CLO4) AND [MN6(3,2,3-TET)4O6(OAC)3]I5.2H2O.4C4H8O | 3 | 20 |
| 383 | 22 | 55 | 1132 1993 FEBS LETTERS 325(1-2):53-58 PEDERSEN JZ; FINAZZIAGRO A PROTEIN-RADICAL ENZYMES | 37 | 56 |
| 384 | 22 | 68 | 1205 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(18):7971-7977 GUAJARDO RJ; HUDSON SE; BROWN SJ; MASCHARAK PK [FE(PMA)]N+ (N = 1, 2) - GOOD MODELS OF FE-BLEOMYCINS AND EXAMPLES OF MONONUCLEAR NONHEME IRON COMPLEXES WITH SIGNIFICANT O2-ACTIVATION CAPABILITIES | 89 | 123 |
| 385 | 22 | 72 | 1546 1995 BIOCHEMISTRY 34(37):12029-12037 KECK MV; HECHT SM SEQUENCE-SPECIFIC HYDROLYSIS OF YEAST TRNA(PHE) MEDIATED BY METAL-FREE BLEOMYCIN | 11 | 24 |
| 386 | 22 | 81 | 1554 1995 BIOCHEMISTRY 34(51):16715-16724 Kane SA; Hecht SM; Sun JS; Garestier T; Helene C Specific cleavage of a DNA triple helix by Fe-II center dot bleomycin | 11 | 23 |
| 387 | 22 | 92 | 1595 1995 COORDINATION CHEMISTRY REVIEWS 144:1-38 MANCHANDA R; BRUDVIG GW; CRABTREE RH HIGH-VALENT OXOMANGANESE CLUSTERS - STRUCTURAL AND MECHANISTIC WORK RELEVANT TO THE OXYGEN-EVOLVING CENTER IN PHOTOSYSTEM-II | 29 | 123 |
| 388 | 22 | 63 | 1713 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(45):11220-11229 HAYASHI Y; KAYATANI T; SUGIMOTO H; SUZUKI M; INOMATA K; et al. SYNTHESIS, CHARACTERIZATION, AND REVERSIBLE OXYGENATION OF MU-ALKOXO DIIRON(II) COMPLEXES WITH THE DINUCLEATING LIGAND N,N,N',N'- TETRAKIS((6-METHYL-2-PYRIDYL)METHYL)-1,3-DIAMINOPROPAN-2-OLATE | 19 | 58 |
| 389 | 22 | 50 | 1922 1996 INORGANIC CHEMISTRY 35(11):3348-3354 Carter PJ; Cheng CC; Thorp HH Oxidation of DNA hairpins by oxoruthenium(IV): Effects of sterics and secondary structure | 7 | 20 |
| 390 | 22 | 44 | 1957 1996 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 1(3):210-220 Atta M; Debaecker N; Andersson KK; Latour JM; Thelander L; et al. EPR and multi-field magnetisation of reduced forms of the binuclear iron centre in ribonucleotide reductase from mouse | 11 | 14 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
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| 483 | 20 | 37 | 3234 2000 NUCLEIC ACIDS RESEARCH 28(24):4856-4864 Pitie R; Burrows CJ; Meunier B Mechanisms of DNA cleavage by copper complexes of 3-Clip-Phen and of its conjugate with a distamycin analogue | 0 | 6 |
| 484 | 20 | 110 | 3242 2000 POLYMERS FOR ADVANCED TECHNOLOGIES 11(8-12):865-872 Sudesh K; Doi Y Molecular design and biosynthesis of biodegradable polyesters | 1 | 5 |
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| 486 | 20 | 124 | 3318 2001 BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1503(1-2):69-82 Chu HA; Hillier W; Law NA; Babcock GT Vibrational spectroscopy of the oxygen-evolving complex and of manganese model compounds | 2 | 24 |
| 487 | 20 | 410 | 3512 2001 NATURAL PRODUCT REPORTS 18(5):465-493 Bugg TDH The development of mechanistic enzymology in the 20th century | 0 | 1 |
| 488 | 20 | 275 | 3753 2002 JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL 189(1):39-66 Shul'pin GB Metal-catalyzed hydrocarbon oxygenations in solutions: The dramatic role of additives: a review | 0 | 27 |
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| 490 | 20 | 65 | 3782 2002 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 124(33):9845-9855 Jin S; Kurtz DM; Liu ZJ; Rose J; Wang BC X-ray crystal structures of reduced rubrerythrin and its azide adduct: A structure-based mechanism for a non-heme diiron peroxidase | 3 | 12 |
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| 491 | 20 | 40 | 3854 2002 TETRAHEDRON 58(29):5789-5801 Crich D; Suk DH; Hao XL The effect of the base in the fragmentation of nucleotide C4 ' radicals | 0 | 3 |
| 492 | 20 | 33 | 3900 2003 BIOCHEMISTRY 42(21):6559-6564 Xia CW; Forsterling FH; Petering DH Identification of the internal axial ligand of HO2-cobalt(III)- bleomycin: H-1{N-15} HSQC NMR investigation of bleomycin, deglycobleomycin, and their hydroperoxide-cobalt(III) complexes | 5 | 5 |
| 493 | 20 | 47 | 3901 2003 BIOCHEMISTRY 42(24):7497-7508 Price JC; Barr EW; Tirupati B; Bollinger JM; Krebs C The first direct characterization of a high-valent iron intermediate in the reaction of an alpha-ketoglutarate-dependent dioxygenase: A high-spin Fe(IV) complex in taurine/alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli | 7 | 27 |
| 494 | 20 | 27 | 4191 2004 BIOCHEMISTRY 43(8):2155-2158 Cheng MC; Marsh ENG Pre-steady-state measurement of intrinsic secondary tritium isotope effects associated with the homolysis of adenosylcobalamin and the formation of 5 '-deoxyadensosine in glutamate mutase | 1 | 1 |
| 495 | 20 | 59 | 4277 2004 DALTON TRANSACTIONS (20):3191-3198 Koehntop KD; Rohde JU; Costas M; Que L XAS characterization of end-on and side-on peroxoiron(III) complexes of the neutral pentadentate N-donor ligand N-methyl-N,N ',N '-tris(2-pyridylmethyl)ethane-1,2-diamine | 0 | 0 |
| 496 | 20 | 90 | 4355 2004 JOURNAL OF INORGANIC BIOCHEMISTRY 98(2):287-300 Brown KL; Zou X; Chen GD; Xia ZP; Marques HM Solution structure, enzymatic, and non-enzymatic reactivity of 3-isoadenosylcobalamin, a structural isomer of coenzyme B-12 with surprising coenzymic activity | 0 | 0 |
| 497 | 19 | 253 | 407 1989 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 28(9):1153-1172 WIEGHARDT K THE ACTIVE-SITES IN MANGANESE-CONTAINING METALLOPROTEINS AND INORGANIC MODEL COMPLEXES | 95 | 564 |
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| 500 | 19 | 540 | 1045 1992 PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY 58(2):85-201 WACHTERSHAUSER G GROUNDWORKS FOR AN EVOLUTIONARY BIOCHEMISTRY - THE IRON SULFUR WORLD | 4 | 138 |
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| 502 | 19 | 66 | 1319 1994 BIOCHEMISTRY 33(43):12776-12786 FOX BG; SHANKLIN J; AI JY; LOEHR TM; SANDERSLOEHR J RESONANCE RAMAN EVIDENCE FOR AN FE-O-FE CENTER IN STEAROYL-ACP DESATURASE - PRIMARY SEQUENCE IDENTITY WITH OTHER DIIRON-OXO PROTEINS | 40 | 133 |
| 503 | 19 | 50 | 1383 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(9):6355-6361 REGNSTROM K; ABERG A; ORMO M; SAHLIN M; SJOBERG BM THE CONSERVED SERINE-211 IS ESSENTIAL FOR REDUCTION OF THE DINUCLEAR IRON CENTER IN PROTEIN R2 OF ESCHERICHIA-COLI RIBONUCLEOTIDE REDUCTASE | 13 | 16 |
| 504 | 19 | 58 | 1415 1994 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 116(3):891-897 PESSIKI PJ; KHANGULOV SV; HO DM; DISMUKES GC STRUCTURAL AND FUNCTIONAL MODELS OF THE DIMANGANESE CATALASE ENZYMES .2. STRUCTURE, ELECTROCHEMICAL, REDOX, AND EPR PROPERTIES | 18 | 70 |
| 505 | 19 | 49 | 1432 1994 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 116(14):6429-6430 ATTA M; ANDERSSON KK; INGEMARSON R; THELANDER L; GRASLUND A EPR STUDIES OF MIXED-VALENT [(FEFEIII)-FE-II] CLUSTERS FORMED IN THE R2 SUBUNIT OF RIBONUCLEOTIDE REDUCTASE FROM MOUSE OR HERPES-SIMPLEX VIRUS - MILD CHEMICAL-REDUCTION OF THE DIFERRIC CENTERS | 24 | 29 |
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| 507 | 19 | 37 | 1628 1995 INORGANICA CHIMICA ACTA 229(1-2):33-38 SYAMALA A; NETHAJI M; CHAKRAVARTY AR AN ASYMMETRIC HOMODINUCLEAR COMPLEX CONTAINING THE MU-OXO-BIS(MU-CARBOXYLATO)DIRUTHENIUM(III) CORE - X-RAY STRUCTURE OF [RU2O(O2CC6H4-P-OME)(3)(EN)(PPH(3))(2)](CLO4)CENTER-DOT-3CHCL(3) | 1 | 6 |
| 508 | 19 | 102 | 1710 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(41):10325-10335 TOMMOS C; TANG XS; WARNCKE K; HOGANSON CW; STYRING S; et al. SPIN-DENSITY DISTRIBUTION, CONFORMATION, AND HYDROGEN-BONDING OF THE REDOX-ACTIVE TYROSINE Y-Z IN PHOTOSYSTEM-II FROM MULTIPLE ELECTRON MAGNETIC-RESONANCE SPECTROSCOPIES - IMPLICATIONS FOR PHOTOSYNTHETIC OXYGEN EVOLUTION | 53 | 158 |
| 509 | 19 | 58 | 1711 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(43):10713-10719 UN S; ATTA M; FONTECAVE M; RUTHERFORD AW G-VALUES AS A PROBE OF THE LOCAL PROTEIN ENVIRONMENT - HIGH-FIELD EPR OF TYROSYL RADICALS IN RIBONUCLEOTIDE REDUCTASE AND PHOTOSYSTEM-II | 52 | 76 |
| 510 | 19 | 143 | 1716 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(46):11455-11470 CRICH D; YAO QW; FILZEN GF CHEMISTRY OF BETA-(PHOSPHATOXY)ALKYL AND BETA-(ACYLOXY)ALKYL RADICALS - MIGRATION REACTIONS - SCOPE AND STEREOSELECTIVITY OF BETA- (PHOSPHATOXY)ALKYL REARRANGEMENT - MECHANISM OF BETA-(PHOSPHATOXY)ALKYL AND BETA-(ACYLOXY)ALKYL MIGRATION | 8 | 25 |
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| 511 | 19 | 48 | 1802 1996 BIOCHEMICAL JOURNAL 320:129-135 Lamarche N; Matton G; Massie B; Fontecave M; Atta M; et al. Production of the R2 subunit of ribonucleotide reductase from herpes simplex virus with prokaryotic and eukaryotic expression systems: Higher activity of R2 produced by eukaryotic cells related to higher iron-binding capacity | 2 | 6 |
| 512 | 19 | 37 | 1819 1996 BIOCHEMISTRY 35(26):8595-8602 Coves J; deFallois LLH; lePape L; Decout JL; Fontecave M Inactivation of Escherichia coli ribonucleotide reductase by 2'-deoxy-2'-mercaptouridine 5'-diphosphate. Electron paramagnetic resonance evidence for a transient protein perthiyl radical | 22 | 31 |
| 513 | 19 | 49 | 2081 1997 ACTA CHEMICA SCANDINAVICA 51(5):533-540 Babcock GT; Espe M; Hoganson C; LydakisSimantiris N; McCracken J; et al. Tyrosyl radicals in enzyme catalysis: Some properties and a focus on photosynthetic water oxidation | 34 | 52 |
| 514 | 19 | 55 | 2122 1997 BIOCHEMISTRY 36(41):12526-12534 Zhang E; Brewer JM; Minor W; Carreira LA; Lebioda L Mechanism of enolase: The crystal structure of asymmetric dimer enolase-2-phospho-D-glycerate/enolase-phosphoenolpyruvate at 2.0 angstrom resolution | 2 | 39 |
| 515 | 19 | 57 | 2176 1997 CURRENT OPINION IN CHEMICAL BIOLOGY 1(3):347-356 Frey PA Radicals in enzymatic reactions | 15 | 23 |
| 516 | 19 | 67 | 2219 1997 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 2(1):37-45 Ai JY; Broadwater JA; Loehr TM; SandersLoehr J; Fox BG Azide adducts of stearoyl-ACP desaturase: A model for mu-1,2 bridging by dioxygen in the binuclear iron active site | 12 | 18 |
| 517 | 19 | 55 | 2239 1997 JOURNAL OF ORGANIC CHEMISTRY 62(2):302-309 Lehmann TE; Berkessel A Stereoselective synthesis of 4'-benzophenone-substituted nucleoside analogs: Photoactive models for ribonucleotide reductases | 6 | 8 |
| 518 | 19 | 53 | 2266 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(16):3656-3664 Calafat AM; Won H; Marzilli LG A new arrangement for the anticancer antibiotics tallysomycin and bleomycin when bound to zinc: An assessment of metal and ligand chirality by NMR and molecular dynamics | 25 | 30 |
| 519 | 19 | 25 | 2270 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(25):5976-5977 Bollinger JM; Chen SX; Parkin SE; Mangravite LM; Ley BA; et al. Differential iron(II) affinity of the sites of the diiron cluster in protein R2 of Escherichia coli ribonucleotide reductase: Tracking the individual sites through the O-2 activation sequence | 24 | 25 |
| 520 | 19 | 38 | 2340 1997 SCIENCE 275(5299):515-518 Shu LJ; Nesheim JC; Kauffmann K; Munck E; Lipscomb JD; et al. An (Fe2O2)-O-IV diamond core structure for the key intermediate Q of methane monooxygenase | 99 | 232 |
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| 521 | 19 | 29 | 2533 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(47):31016-31020 Persson AL; Sahlin M; Sjoberg BM Cysteinyl and substrate radical formation in active site mutant E441Q of Escherichia coli class I ribonucleotide reductase | 21 | 23 |
| 522 | 19 | 53 | 2536 1998 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 3(3):307-313 Whittington DA; Valentine AM; Lippard SJ Substrate binding and C-H bond activation in the soluble methane monooxygenase hydroxylase | 12 | 27 |
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| 525 | 19 | 179 | 2624 1998 PHOTOSYNTHESIS: MOLECULAR BIOLOGY OF ENERGY CAPTURE 297:337-360 Diner BA Application of spectroscopic techniques to the study of photosystem II mutations engineered in Synechocystis and Chlamydomonas | 0 | 12 |
| 526 | 19 | 36 | 2979 2000 BIOCHEMICAL JOURNAL 347:97-104 Sun YM; Conner J Characterization of heterosubunit complexes formed by the R1 and R2 subunits of herpes simplex virus 1 and equine herpes virus 4 ribonucleotide reductase | 0 | 0 |
| 527 | 19 | 58 | 3092 2000 INORGANIC CHEMISTRY 39(8):1779-1786 Chikira M; Iiyama T; Sakamoto K; Antholine WE; Petering DH Orientation of iron bleomycin and porphyrin complexes on DNA fibers | 8 | 14 |
| 528 | 19 | 42 | 3118 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(4):2463-2471 Torrents E; Buist G; Liu A; Eliasson R; Kok J; et al. The anaerobic (Class III) ribonucleotide reductase from Lactococcus lactis - Catalytic properties and allosteric regulation of the pure enzyme system | 8 | 15 |
| 529 | 19 | 28 | 3168 2000 JOURNAL OF PHYSICAL CHEMISTRY B 104(31):7502-7509 Himo F; Siegbahn PEM Very stable ribonucleotide substrate radical relevant for class I ribonucleotide reductase | 14 | 22 |
| 530 | 19 | 31 | 3184 2000 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 122(15):3789-3790 Zheng H; Yoo SJ; Munck E; Que L The flexible Fe-2(mu-O)(2) diamond core: A terminal iron(IV)-oxo species generated from the oxidation of a bis(mu-oxo)diiron(III) complex | 14 | 31 |
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| 531 | 19 | 63 | 3197 2000 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 122(33):8031-8036 Himo F; Eriksson LA; Maseras F; Siegbahn PEM Catalytic mechanism of galactose oxidase: A theoretical study | 12 | 36 |
| 532 | 19 | 39 | 3210 2000 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 122(49):12207-12219 Krebs C; Chen SX; Baldwin J; Ley BA; Patel U; et al. Mechanism of rapid electron transfer during oxygen activation in the R2 subunit of Escherichia coli ribonucleotide reductase. 2. Evidence for and consequences of blocked electron transfer in the W48F variant | 23 | 24 |
| 533 | 19 | 51 | 3238 2000 ORGANIC LETTERS 2(21):3397-3399 Leitheiser CJ; Rishel MJ; Wu XH; Hecht SM Solid-phase synthesis of bleomycin group antibiotics. Elaboration of deglycobleomycin A(5) | 13 | 15 |
| 534 | 19 | 143 | 3279 2001 ANNUAL REVIEW OF BIOCHEMISTRY 70:209-246 Gerlt JA; Babbitt PC Divergent evolution of enzymatic function: Mechanistically diverse superfamilies and functionally distinct suprafamilies | 1 | 73 |
| 535 | 19 | 61 | 3384 2001 INORGANIC CHEMISTRY 40(7):1557-1561 Fedeles F; Zimmer M Conformational/configurational analysis of all the binding geometries of cobalt(III) bleomycin | 3 | 4 |
| 536 | 19 | 59 | 3395 2001 INORGANICA CHIMICA ACTA 318(1-2):45-52 Sams CK; Somoza F; Bernal I; Toftlund H Coordination chemistry of transition metal complexes of a novel pentadentate ligand | 0 | 5 |
| 537 | 19 | 69 | 3424 2001 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 6(1):27-45 Siegbahn PEM O-O bond cleavage and alkane hydroxylation in methane monooxygenase | 11 | 39 |
| 538 | 19 | 40 | 3536 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(18):10073-10078 Voegtli WC; Ge J; Perlstein DL; Stubbe J; Rosenzweig AC Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer | 9 | 9 |
| 539 | 19 | 44 | 3579 2002 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 59(4-5):477-482 Amara AA; Steinbuchel A; Rehm BHA In vivo evolution of the Aeromonas punctata polyhydroxyalkanoate (PHA) synthase: isolation and characterization of modified PHA synthases with enhanced activity | 6 | 8 |
| 540 | 19 | 45 | 3701 2002 INORGANICA CHIMICA ACTA 340:170-180 Kong DY; Reibenspies J; Mao JG; Martell AE; Clearfield A Syntheses, systematic potentiometry and structural studies of 26-membered hexaaza-diphenolate-based macrocyclic diiron complexes | 0 | 1 |
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| 541 | 19 | 45 | 3715 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(3):2311-2320 Sugiyama M; Kumagai T; Hayashida M; Maruyama M; Matoba Y The 1.6-A crystal structure of the copper(II)-bound bleomycin complexed with the bleomycin-binding protein from bleomycin-producing Streptomyces verticillus | 12 | 13 |
| 542 | 19 | 81 | 3780 2002 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 124(32):9476-9488 Zou Y; Fahmi NE; Vialas C; Miller GM; Hecht SM Total synthesis of deamido bleomycin A(2), the major catabolite of the antitumor agent bleomycin | 2 | 6 |
| 543 | 19 | 56 | 3805 2002 MICROBIOLOGY-SGM 148:391-404 Borovok I; Kreisberg-Zakarin R; Yanko M; Schreiber R; Myslovati M; et al. Streptomyces spp. contain class Ia and class II ribonucleotide reductases: expression analysis of the genes in vegetative growth | 3 | 3 |
| 544 | 19 | 63 | 3821 2002 NUCLEIC ACIDS RESEARCH 30(24):5497-5508 Junker HD; Hoehn ST; Bunt RC; Marathius V; Chen JY; et al. Synthesis, characterization and solution structure of tethered oligonucleotides containing an internal 3 '-phosphoglycolate, 5 '-phosphate gapped lesion | 2 | 2 |
| 545 | 19 | 49 | 3893 2003 BIOCHEMISTRY 42(8):2449-2455 Kroeger KM; Hashimoto M; Kow YW; Greenberg MM Cross-linking of 2-deoxyribonolactone and its beta-elimination product by base excision repair enzymes | 3 | 9 |
| 546 | 19 | 66 | 3897 2003 BIOCHEMISTRY 42(19):5857-5866 Lyle KS; Haas JA; Fox BG Rapid-mix and chemical quench studies of ferredoxin-reduced stearoyl-acyl carrier protein desaturase | 1 | 4 |
| 547 | 19 | 53 | 3952 2003 CURRENT OPINION IN BIOTECHNOLOGY 14(5):475-483 Aldor AS; Keasling JD Process design for microbial plastic factories: metabolic engineering of polyhydroxyalkanoates | 0 | 0 |
| 548 | 19 | 66 | 3959 2003 CURRENT OPINION IN MICROBIOLOGY 6(3):251-260 Luengo JM; Garcia B; Sandoval A; Naharro G; Olivera ER Bioplastics from microorganisms | 1 | 1 |
| 549 | 19 | 28 | 3994 2003 JOURNAL OF BACTERIOLOGY 185(4):1167-1173 Ekberg M; Birgander P; Sjoberg BM In vivo assay for low-activity mutant forms of Escherichia coli ribonucleotide reductase | 4 | 4 |
| 550 | 19 | 80 | 4036 2003 JOURNAL OF PHYSICAL CHEMISTRY B 107(1):306-315 Dolker N; Maseras F; Lledos A Density functional study on the effect of the trans axial ligand of B-12 cofactors on the heterolytic cleavage of the Co-C bond | 2 | 7 |
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| 551 | 19 | 82 | 4097 2003 MOLECULAR GENETICS AND GENOMICS 269(1):78-89 Leduc A; He CH; Ramotar D Disruption of the Saccharomyces cerevisiae cell-wall pathway gene SLG1 causes hypersensitivity to the antitumor drug bleomycin | 2 | 4 |
| 552 | 19 | 68 | 4263 2004 CHEMISTRY-A EUROPEAN JOURNAL 10(11):2781-2788 Semialjac M; Schwarz H Computational investigation of hydrogen abstraction from 2-aminoethanol by the 1,5-dideoxyribose-5-yl radical: A model study of a reaction occurring in the active site of ethanolamine ammonia lyase | 0 | 0 |
| 553 | 19 | 58 | 4342 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(51):52840-52849 Chang CH; Svedruzic D; Ozarowski A; Walker L; Yeagle G; et al. EPR spectroscopic characterization of the manganese center and a free radical in the oxalate decarboxylase reaction - Identification of a tyrosyl radical during turnover | 0 | 0 |
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| 555 | 18 | 52 | 1202 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(16):7135-7138 URATA H; UEDA Y; USAMI Y; AKAGI M ENANTIOSPECIFIC RECOGNITION OF DNA BY BLEOMYCIN | 6 | 11 |
| 556 | 18 | 68 | 1312 1994 BIOCHEMISTRY 33(34):10286-10293 MORGAN MA; HECHT SM IRON(II) BLEOMYCIN-MEDIATED DEGRADATION OF A DNA-RNA HETERODUPLEX | 20 | 22 |
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| 559 | 18 | 47 | 1462 1994 NATURE 370(6490):533-539 UHLIN U; EKLUND H STRUCTURE OF RIBONUCLEOTIDE REDUCTASE PROTEIN R1 | 214 | 253 |
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| 561 | 18 | 72 | 1705 1995 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 117(35):8908-8916 VANDERDONK WA; STUBBE J; GERFEN GJ; BELLEW BF; GRIFFIN RG EPR INVESTIGATIONS OF THE INACTIVATION OF ESCHERICHIA-COLI RIBONUCLEOTIDE REDUCTASE WITH 2'-AZIDO-2'-DEOXYURIDINE 5'-DIPHOSPHATE - EVIDENCE FOR THE INVOLVEMENT OF THE THIYL RADICAL OF C225-R1 | 46 | 44 |
| 562 | 18 | 47 | 1788 1996 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH 35(6):618-620 Dong YH; Yan SP; Young VG; Que L Crystal structure analysis of a synthetic non-heme diiron-O-2 adduct: Insight into the mechanism of oxygen activation | 37 | 90 |
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| 564 | 18 | 130 | 1965 1996 JOURNAL OF MEDICINAL CHEMISTRY 39(11):2103-2117 Smith AL; Nicolaou KC The enediyne antibiotics | 19 | 121 |
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| 568 | 18 | 201 | 2175 1997 CURRENT MEDICINAL CHEMISTRY 4(5):313-358 Sondhi SM; Reddy BSP; Lown JW Lexitropsin conjugates: Action on DNA targets | 0 | 27 |
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| 570 | 18 | 45 | 2283 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(41):9816-9824 Willems JP; Lee HI; Burdi D; Doan PE; Stubbe J; et al. Identification of the protonated oxygenic ligands of ribonucleotide reductase intermediate X by Q-band H-1,H-2 CW and pulsed ENDOR | 60 | 60 |
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| 571 | 18 | 52 | 2288 1997 JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS (5):887-893 Graham B; Moubaraki B; Murray KS; Spiccia L; Cashion JD; et al. Syntheses and characterisation of mono-and di-nuclear iron(III) complexes of 1,4,7-triazacyclononane-N-acetate (L). Crystal structures of [FeCl(2)L] and [Fe-2(mu-O)(mu-O(2)CMe)L(2)]ClO4 center dot NaClO4 center dot 2H(2)O | 0 | 9 |
| 572 | 18 | 34 | 2330 1997 POLYHEDRON 16(9):1497-1503 Akamatsu T; Kobayashi T; Sasaki Y; Ito S; Nishida Y High activity for oxidation reaction by peroxide adduct of binuclear iron(III) compound with (mu-eta(1):eta(1))-coordination mode | 1 | 4 |
| 573 | 18 | 31 | 2354 1997 TRENDS IN BIOCHEMICAL SCIENCES 22(3):81-85 Reichard P The evolution of ribonucleotide reduction | 33 | 51 |
| 574 | 18 | 58 | 2528 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(34):22136-22144 Guittet O; Ducastel B; Salem JS; Henry Y; Rubin H; et al. Differential sensitivity of the tyrosyl radical of mouse ribonucleotide reductase to nitric oxide and peroxynitrite | 2 | 22 |
| 575 | 18 | 41 | 2562 1998 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 120(5):955-962 Wilkinson EC; Dong YH; Zang Y; Fujii H; Fraczkiewicz R; et al. Raman signature of the Fe2O2 "diamond" core | 11 | 29 |
| 576 | 18 | 281 | 2639 1998 RADIATION RESEARCH 150(5):S60-S79 Wallace SS Enzymatic processing of radiation-induced free radical damage in DNA | 0 | 75 |
| 577 | 18 | 53 | 2767 1999 INORGANIC CHEMISTRY 38(8):1929-1936 Roelfes G; Lubben M; Chen K; Ho RYN; Meetsma A; et al. Iron chemistry of a pentadentate ligand that generates a metastable Fe-III-OOH intermediate | 23 | 55 |
| 578 | 18 | 73 | 2780 1999 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 25(1-3):3-19 Rehm BHA; Steinbuchel A Biochemical and genetic analysis of PHA synthases and other proteins required for PHA synthesis | 40 | 64 |
| 579 | 18 | 61 | 2855 1999 JOURNAL OF PHYSICAL CHEMISTRY B 103(22):4764-4772 Wise KE; Pate JB; Wheeler RA Phenoxyl, (methylthio)phenoxyl, and (methylthio)cresyl radical models for the structures, vibrations, and spin properties of the cysteine-linked tyrosyl radical in galactose oxidase | 8 | 16 |
| 580 | 18 | 30 | 2871 1999 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 121(24):5823-5824 Robins MJ; Ewing GJ Nucleic acid related compounds. 109. Biomimetic modeling of the first substrate reaction at the active site of ribonucleotide reductases. Abstraction of H3 ' by a thiyl free radical | 8 | 11 |
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| 581 | 18 | 55 | 2906 1999 MICROBIOLOGY-SGM 145:1595-1604 Oehlmann W; Auling G Ribonucleotide reductase (RNR) of Corynebacterium glutamicum ATCC 13032 - genetic characterization of a second class IV enzyme | 2 | 4 |
| 582 | 18 | 36 | 2998 2000 BIOCHEMISTRY 39(31):9241-9250 Erickson HK Formation of the cystine between cysteine 225 and cysteine 462 from ribonucleoside diphosphate reductase is kinetically competent | 6 | 7 |
| 583 | 18 | 33 | 3023 2000 BIOORGANIC & MEDICINAL CHEMISTRY 8(5):1065-1073 Highfield JA; Mehta LK; Parrick J; Wardman P Synthesis, hydroxyl radical production and cytotoxicity of analogues of bleomycin | 0 | 2 |
| 584 | 18 | 146 | 3039 2000 CELLULAR AND MOLECULAR LIFE SCIENCES 57(1):106-127 Toraya T Radical catalysis of B-12 enzymes: structure, mechanism, inactivation, and reactivation of diol and glycerol dehydratases | 18 | 32 |
| 585 | 18 | 44 | 3062 2000 COORDINATION CHEMISTRY REVIEWS 198:3-20 Itoh S; Taki M; Fukuzumi S Active site models for galactose oxidase and related enzymes | 10 | 32 |
| 586 | 18 | 41 | 3163 2000 JOURNAL OF PHYSICAL CHEMISTRY A 104(21):5149-5153 Engstrom M; Himo F; Graslund A; Minaev B; Vahtras O; et al. Hydrogen bonding to tyrosyl radical analyzed by ab initio g-tensor calculations | 11 | 21 |
| 587 | 18 | 89 | 3202 2000 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 122(39):9525-9533 Chatgilialoglu C; Ferreri C; Bazzanini R; Guerra M; Choi SY; et al. Models of DNA C1 ' radicals. Structural, spectral, and chemical properties of the thyminylmethyl radical and the 2 '-deoxyuridin-1 '-yl radical | 3 | 20 |
| 588 | 18 | 238 | 3235 2000 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 19(10-12):1615-1656 Foldesi A; Trifonova A; Kundu MK; Chattopadhyaya J The synthesis of deuterionucleosides | 2 | 9 |
| 589 | 18 | 39 | 3249 2000 SCIENCE 287(5450):122-125 Hwang J; Krebs C; Huynh BH; Edmondson DE; Theil EC; et al. A short Fe-Fe distance in peroxodiferric ferritin: Control of Fe substrate versus cofactor decay? | 20 | 49 |
| 590 | 18 | 30 | 3256 2000 TETRAHEDRON LETTERS 41(49):9493-9498 Boger DL; Aquila BM; Tse WC; Searcey M Synthesis and evaluation of a novel bleomycin A(2) analogue: continuing assessment of the linker domain | 1 | 2 |
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| 591 | 18 | 44 | 3298 2001 BIOCHEMISTRY 40(6):1651-1661 Scott CP; Kashlan OB; Lear JD; Cooperman BS A quantitative model for allosteric control of purine reduction by murine ribonucleotide reductase | 7 | 13 |
| 592 | 18 | 238 | 3354 2001 CURRENT MEDICINAL CHEMISTRY 8(5):551-581 Han XG; Gao XL Sequence specific recognition of ligand-DNA complexes studied by NMR | 0 | 8 |
| 593 | 18 | 66 | 3369 2001 EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (11):2823-2829 Mukhopadhyay U; Falvello LR; Ray D Synthesis and crystal structure of a novel binucleating symmetrical mu-bis(tetradentate) Schiff base ligand: Syntheses and redox properties of dimanganese(III/III) complexes | 0 | 2 |
| 594 | 18 | 56 | 3389 2001 INORGANIC CHEMISTRY 40(12):2810-2817 Rowland JM; Olmstead M; Mascharak PK Syntheses, structures, and reactivity of low spin iron(III) complexes containing a single carboxamido nitrogen in a [FeN5L] chromophore | 3 | 24 |
| 595 | 18 | 70 | 3400 2001 ISRAEL JOURNAL OF CHEMISTRY 41(3):173-186 Baik MH; Lee D; Friesner RA; Lippard SJ Theoretical studies of diiron(II) complexes that model features of the dioxygen-activating centers in non-heme diiron enzymes | 3 | 7 |
| 596 | 18 | 35 | 3429 2001 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 6(5-6):618-627 Li WB; Xia CW; Antholine WE; Petering DH Interactions of iron bleomycin, phosphate or cyanide, and DNA: sequence-dependent conformations and reactions | 4 | 4 |
| 597 | 18 | 61 | 3485 2001 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 123(30):7388-7398 Zhou J; Kelly WL; Bachmann BO; Gunsior M; Townsend CA; et al. Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: Correlation with mechanisms and reactivities | 10 | 25 |
| 598 | 18 | 46 | 3535 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(18):10067-10072 Ge H; Perlstein DL; Nguyen HH; Bar G; Griffin RG; et al. Why multiple small subunits (Y2 and Y4) for yeast ribonucleotide reductase? Toward understanding the role of Y4 | 1 | 1 |
| 599 | 18 | 38 | 3597 2002 BIOCHEMISTRY 41(9):3200-3206 Huhta MS; Ciceri D; Golding BT; Marsh ENG A novel reaction between adenosylcobalamin and 2-methyleneglutarate catalyzed by glutamate mutase | 6 | 9 |
| 600 | 18 | 37 | 3742 2002 JOURNAL OF INORGANIC BIOCHEMISTRY 90(1-2):8-17 Li WB; Antholine WE; Petering DH Kinetics of reaction of DNA-bound Fe(III)bleomycin with ascorbate: interplay of specific and non-specific binding | 1 | 1 |
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