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Mon May 1 15:08:55 2006

Papers by RJ Lefkowitz

Nodes: 972, Authors: 1059, Journals: 155, Outer References: 9343, Words: 1778
Yearly output  |  Document Type  |  Language  |  Institution  |  Institution with Subdivision  |  Country
Collection span: 1970 - 2006
View: Overview   Sorted by year, source, volume, issue, page.

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#LCRNCRNode / Date / Journal / AuthorLCSGCS
70100701 1996 CIRCULATION 94 (8): 243-243
Gaballa MA; Peppel K; Lefkowitz RJ; Aqurrie M; Dolber PC; et al.
Gene transfer of beta2-adrenergic receptors enhances vasorelaxation in rat carotid arterial wall
00
70200702 1996 CIRCULATION 94 (8): 1676-1676
Korzick DH; Xiao RP; Ziman BD; Koch MJ; Lefkowitz RJ; et al.
Genetic manipulation of the beta-adrenergic receptor kinase (beta ARK1) modifies contractile response to beta(1)-adrenergic stimulation in single cardiac myocytes
00
70300703 1996 CIRCULATION 94 (8): 2251-2251
Rockman HA; Lefkowitz RJ; Koch WJ
Blunted contractility in conscious transgenic mice overexpressing the G protein coupled receptor kinase-5
00
70400704 1996 CIRCULATION 94 (8): 2373-2373
Akhter SA; Milano CA; Lefkowitz RJ; Koch WJ
Specific interactions between adrenergic receptors and receptor kinases in the hearts of hybrid transgenic mice
00
70500705 1996 CIRCULATION 94 (8): 2374-2374
Milano CA; Akhter SA; Koch WJ; Dolber PC; Rindt H; et al.
Functional effects of myocardial alpha-adrenergic receptor overexpression in transgenic mice.
00
70600706 1996 CIRCULATION 94 (8): 2375-2375
Tsimikas S; Koch WJ; Lefkowitz RJ; Rockman HA
Desensitization of adenosine A1 receptors with cardiac overexpression of the G protein-coupled receptor kinase 5 in transgenic mice.
00
7071029707 1996 CIRCULATION RESEARCH 78 (4): 511-516
Koch WJ; Milano CA; Lefkowitz RJ
Transgenic manipulation of myocardial G protein-coupled receptors and receptor kinases
829
70824269708 1996 ENDOCRINE REVIEWS 17 (6): 698-714
vanBiesen T; Luttrell LM; Hawes BE; Lefkowitz RJ
Mitogenic signaling via G protein-coupled receptors
13317
70900709 1996 FASEB JOURNAL 10 (6): 786-786
Ishizaka N; Griendling K; Fukui T; Oppermann M; Lefkowitz RJ; et al.
Functional interaction between angiotensin II and GRK5 in cultured vascular smooth muscle cells (VSMC) and rat aorta.
00
710536710 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (3): 1266-1269
vanBiesen T; Hawes BE; Raymond JR; Luttrell LM; Koch WJ; et al.
G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism
4163
#LCRNCRNode / Date / Journal / AuthorLCSGCS
7111449711 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (7): 3771-3778
Tiberi M; Nash SR; Bertrand L; Lefkowitz RJ; Caron MG
Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases
677
7121439712 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (11): 6403-6410
Premont RT; Macrae AD; Stoffel RH; Chung NJ; Pitcher JA; et al.
Characterization of the G protein-coupled receptor kinase GRK4 - Identification of four splice variants
1084
713749713 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (21): 12133-12136
Hawes BE; Luttrell LM; vanBiesen T; Lefkowitz RJ
Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway
6247
7141138714 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (22): 13266-13272
Oppermann M; Freedman NJ; Alexander RW; Lefkowitz RJ
Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C
15152
7151429715 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (23): 13796-13803
Fredericks ZL; Pitcher JA; Lefkowitz RJ
Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta(2)-adrenergic receptor
9129
716757716 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (32): 19443-19450
Luttrell LM; Hawes BE; vanBiesen T; Luttrell DK; Lansing TJ; et al.
Role of c-Src tyrosine kinase in G protein-coupled receptor-and G beta gamma subunit-mediated activation of mitogen-activated protein kinases
14360
7171235717 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (40): 24907-24913
Pitcher JA; Fredericks ZL; Stone WC; Premont RT; Stoffel RH; et al.
Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity - Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies
1179
718131718 1996 JOURNAL OF CLINICAL INVESTIGATION 97 (7): 1618-1623
Rockman HA; Hamilton R; Jones LR; Milano CA; Mao L; et al.
Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta(2)-adrenergic receptor is associated with reduced phospholamban protein
448
71918719 1996 JOURNAL OF CLINICAL INVESTIGATION 98 (2): 241-241
Bond RA; Lefkowitz RJ
The third beta is not the charm
04
72000720 1996 JOURNAL OF INVESTIGATIVE MEDICINE 44 (3): A271-A271
Luttrell LM; Hawes BE; vanBiesen T; Luttrell DK; Lefkowitz RJ
An essential role for SRC tyrosine kinase SHC adapter protein complexes in G beta gamma subunit-mediated mitogen-activated protein kinase activation.
00
#LCRNCRNode / Date / Journal / AuthorLCSGCS
72100721 1996 JOURNAL OF LEUKOCYTE BIOLOGY : 203-203
Oppermann M; Kirchhoff S; Lefkowitz RJ
Monoclonal antibodies reveal receptor specificity among G protein-coupled receptor kinases.
00
72200722 1996 JOURNAL OF LEUKOCYTE BIOLOGY : 205-205
Oppermann M; Kirchhoff S; Lefkowitz RJ
Monoclonal antibodies reveal receptor specificity among G protein-coupled receptor kinases
00
7231332723 1996 JOURNAL OF MOLECULAR MEDICINE-JMM 74 (9): 489-495
Rockman HA; Koch WJ; Milano CA; Lefkowitz RJ
Myocardial beta-adrenergic receptor signaling in vivo: Insights from transgenic mice
220
72400724 1996 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 7 (9): A2143-A2143
Garnovskaya MN; vanBiesen T; Hawes B; Lefkowitz RJ; Raymond JR
Divergent pertussis toxin-sensitive pathways for 5-HT1A receptor activation of NHE & ERK
00
72500725 1996 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 7 (9): A2144-A2144
Garnovskaya MN; vanBiesen T; Lefkowitz RJ; Raymond JR
Specific alpha-subunits of the G(i/o/z) family of hererotrimeric G-proteins mediate acute agonist-induced activation of fibroblast NHE.
00
726126726 1996 MOLECULAR BRAIN RESEARCH 42 (2): 245-254
Macrae AD; Premont RT; Jaber M; Peterson AS; Lefkowitz RJ
Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain
031
7271627727 1996 NATURE BIOTECHNOLOGY 14 (3): 283-286
Lefkowitz RJ
G protein-coupled receptors and receptor kinases: From molecular biology to potential therapeutic applications
226
7281940728 1996 NEURON 16 (3): 579-585
DiversePierluissi M; Inglese J; Stoffel RH; Lefkowitz RJ; Dunlap K
G protein-coupled receptor kinase mediates desensitization of norepinephrine-induced Ca2+ channel inhibition
234
7291825729 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93 (15): 7649-7654
Oppermann M; DiversePierluissi H; Drazner MH; Dyer SL; Freedman NJ; et al.
Monoclonal antibodies reveal receptor specificity G-protein-coupled receptor kinases
1660
7301027730 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93 (18): 9954-9959
Rockman HA; Choi DJ; Rahman NU; Akhter SA; Lefkowitz RJ; et al.
Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice
2195
#LCRNCRNode / Date / Journal / AuthorLCSGCS
731431731 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93 (23): 12974-12979
Jaber M; Koch WJ; Rockman H; Smith B; Bond RA; et al.
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function
20108
73252107732 1996 RECENT PROGRESS IN HORMONE RESEARCH, VOL 51 51: 319-353
Freedman NJ; Lefkowitz RJ
Desensitization of G protein-coupled receptors
29285
733421733 1996 RECEPTORS & CHANNELS 4 (3): 197-203
Sizmann D; Kuusinen H; Keranen S; Lomasney J; Caron MG; et al.
Production of adrenergic receptors in yeast
015
7341131734 1997 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 41 (1): H590-H596
Korzick DH; Xiao RP; Ziman BD; Koch WJ; Lefkowitz RJ; et al.
Transgenic manipulation of beta-adrenergic receptor kinase modifies cardiac myocyte contraction to norepinephrine
020
7351447735 1997 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 41 (4): H1553-H1559
Rockman HA; Koch WJ; Lefkowitz RJ
Cardiac function in genetically engineered mice with altered adrenergic receptor signaling
044
73600736 1997 BIOPHYSICAL JOURNAL 72 (2): TUAM2-TUAM2
Xiao RP; Avdonin P; Akliter SA; Zhou YY; Ziman B; et al.
Dual coupling of beta(2)-adrenergic receptor to G(i) as well as to G(s) in cardiac myocytes
00
73700737 1997 CIRCULATION 96 (8): 1632-1632
Choi DJ; Koch WJ; Rockman HA; Akhter SA; Lefkowitz RJ; et al.
Level of beta ARK1 regulates myocardial contractile function in gene targeted mice
00
73800738 1997 CIRCULATION 96 (8): 1635-1635
Akhter SA; Luttrell LM; Rockman HA; Lefkowitz RJ; Koch WJ
Attenuation of pressure overload hypertrophy in transgenic mice expressing an inhibitor of G(q)-coupled signaling
00
73900739 1997 CIRCULATION 96 (8): 2773-2773
Iaccarino G; Lefkowitz RJ; Koch WJ
Reciprocal regulation of myocardial beta ARK1 by beta adrenergic agonists and antagonists
00
74000740 1997 CIRCULATION 96 (8): 3744-3744
Kypson AP; Akhter SA; Peppel K; Hendrickson SC; McDonald P; et al.
Adenoviral-mediated gene transfer of the beta(2)-adrenergic receptor improves function of the transplanted rat heart
00
#LCRNCRNode / Date / Journal / AuthorLCSGCS
741643741 1997 ENDOCRINOLOGY 138 (1): 369-378
Ledent C; Denef JF; Cottecchia S; Lefkowitz RJ; Dumont J; et al.
Costimulation of adenylyl cyclase and phospholipase C by a mutant alpha(1B)-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells
017
74200742 1997 FASEB JOURNAL 11 (9): A873-A873
Lefkowitz RJ
G protein-coupled receptors and their regulation.
00
74300743 1997 FASEB JOURNAL 11 (9): A1341-A1341
Skiba N; Bae H; Ford C; Daaka Y; Reuveny E; et al.
Molecular basis for G beta gamma-effector interaction: Structural correlation with GA binding site.
00
7441231744 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (1): 5-8
Krueger KM; Daaka Y; Pitcher JA; Lefkowitz RJ
The role of sequestration in G protein-coupled receptor resensitization - Regulation of beta(2)-adrenergic receptor dephosphorylation by vesicular acidification
15207
745832745 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (7): 4606-4612
Boekhoff I; Touhara K; Danner S; Inglese J; Lohse MJ; et al.
Phosducin, potential role in modulation of olfactory signaling
128
746548746 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (7): 4637-4644
Luttrell LM; DellaRocca GJ; vanBiesen T; Luttrell DK; Lefkowitz RJ
G beta gamma subunits Src-dependent phosphorylation of the epidermal growth factor receptor - A scaffold for G protein-coupled receptor-mediated Ras activation
13313
7471752747 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (28): 17734-17743
Freedman NJ; Ament AS; Oppermann M; Stoffel RH; Exum ST; et al.
Phosphorylation and desensitization of human endothelin A and B receptors - Evidence for G protein-coupled receptor kinase specificity
12106
7481247748 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (31): 19125-19132
DellaRocca GJ; vanBiesen T; Daaka Y; Luttrell DK; Luttrell LM; et al.
Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors - Convergence of G(i)- and G(q)-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase
5294
749929749 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (34): 21253-21259
Akhter SA; Milano CA; Shotwell KF; Cho MC; Rockman HA; et al.
Transgenic mice with cardiac overexpression of alpha(1B)-adrenergic receptors - In vivo alpha(1)-adrenergic receptor-mediated regulation of beta-adrenergic signaling
383
750825750 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (41): 25425-25428
Peppel K; Boekhoff I; McDonald P; Breer H; Caron MG; et al.
G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization
1556
#LCRNCRNode / Date / Journal / AuthorLCSGCS
7511043751 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (49): 31051-31057
Lin FT; Krueger KM; Kendall HE; Daaka Y; Fredericks ZL; et al.
Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1
2195
752951752 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (50): 31648-31656
Luttrell LM; Daaka Y; DellaRocca GJ; Lefkowitz RJ
G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts - Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases
11115
7531035753 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (51): 32482-32488
Ishizaka N; Alexander RW; Laursen JB; Kai H; Fukui T; et al.
G protein-coupled receptor kinase 5 in cultured vascular smooth muscle cells and rat aorta - Regulation by angiotensin II and hypertension
031
754837754 1997 JOURNAL OF CLINICAL INVESTIGATION 99 (2): 288-296
Drazner MH; Peppel KC; Dyer S; Grant AO; Koch WJ; et al.
Potentiation of beta-adrenergic signaling by adenoviral-mediated gene transfer in adult rabbit ventricular myocytes
1178
7551949755 1997 JOURNAL OF MEMBRANE BIOLOGY 157 (1): 1-8
Stoffel RH; Pitcher JA; Lefkowitz RJ
Targeting G protein-coupled receptor kinases to their receptor substrates
330
756216756 1997 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 29 (3): 961-967
Bittner HB; Chen EP; Milano CA; Lefkowitz RJ; VanTrigt P
Functional analysis of myocardial performance in murine hearts overexpressing the human beta(2)-adrenergic receptor
08
7571535757 1997 MOLECULAR PHARMACOLOGY 51 (5): 800-808
Menard L; Ferguson SSG; Zhang J; Lin FT; Lefkowitz RJ; et al.
Synergistic regulation of beta(2)-adrenergic receptor sequestration: Intracellular complement of beta-adrenergic receptor kinase and beta-arrestin determine kinetics of internalization
9150
758928758 1997 NATURE 390 (6655): 88-91
Daaka Y; Luttrell LM; Lefkowitz RJ
Switching of the coupling of the beta(2)-adrenergic receptor to different G proteins by protein kinase A
26456
7591254759 1997 PROCEEDINGS OF THE ASSOCIATION OF AMERICAN PHYSICIANS 109 (3): 220-227
Drazner MH; Koch WJ; Lefkowitz RJ
Potentiation of beta-adrenergic signaling by gene transfer
16
760816760 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (1): 137-141
Samama P; Bond RA; Rockman HA; Milano CA; Lefkowitz RJ
Ligand-induced overexpression of a constitutively active beta(2)- adrenergic receptor: Pharmacological creation of a phenotype in transgenic mice
252
#LCRNCRNode / Date / Journal / AuthorLCSGCS
7611627761 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (6): 2180-2185
Daaka Y; Pitcher JA; Richardson M; Stoffel RH; Robishaw JD; et al.
Receptor and G beta gamma isoform-specific interactions with G protein-coupled receptor kinases
9100
762722762 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (22): 12100-12105
Akhter SA; Skaer CA; Kypson AP; McDonald PH; Peppel KC; et al.
Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer
17107
763919763 1997 RECEPTORS & CHANNELS 5 (3-4): 193-199
Zhang J; Ferguson SSG; Barak LS; Aber MJ; Giros B; et al.
Mini-Review - Molecular mechanisms of G protein-coupled receptor signaling: Role of G protein-coupled receptor kinases and arrestins in receptor desensitization and resensitization
355
7641383764 1997 SIGNAL TRANSDUCTION IN HEALTH AND DISEASE 31: 263-277
Luttrell LM; vanBiesen T; Hawes BE; Koch WJ; Krueger KM; et al.
G-protein-coupled receptors and their regulation - Activation of the MAP kinase signaling pathway by G-protein-coupled receptors
261
765651765 1997 TRENDS IN CARDIOVASCULAR MEDICINE 7 (5): 145-150
Peppel K; Koch WJ; Lefkowitz RJ
Gene transfer strategies for augmenting cardiac function
18
76680251766 1998 ANNUAL REVIEW OF BIOCHEMISTRY 67: 653-692
Pitcher JA; Freedman NJ; Lefkowitz RJ
G protein-coupled receptor kinases
52472
767629767 1998 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 18 (8): 1275-1280
Davies MG; Huynh TTT; Fulton GJ; Lefkowitz RJ; Svendsen E; et al.
G protein signaling and vein graft intimal hyperplasia - Reduction of intimal hyperplasia in vein grafts by a G(beta gamma) inhibitor suggests a major role of G protein signaling in lesion development
018
7681240768 1998 BIOCHEMISTRY 37 (46): 16053-16059
Stoffel RH; Inglese J; Macrae AD; Lefkowitz RJ; Premont RT
Palmitoylation increases the kinase activity of the G protein-coupled receptor kinase, GRK6
417
76900769 1998 BIOPHYSICAL JOURNAL 74 (2): A35-A35
Heath B; An RH; Koch W; Lefkowitz RJ; Kass RS
Targeting of cAMP-dependent increases in L-type Ca+2 (I-Ca) over delayed K+ channel (I-Ks) activity by overexpression of the beta(2)- adrenergic receptor (beta(2)AR) in the developing mouse heart.
00
77000770 1998 CIRCULATION 98 (17): 69-69
Iaccarino G; Lefkowitz RJ; Koch WJ
Increased mortality and cardiac beta ARK1 levels in mice with cardiac overexpression of the alpha 1b adrenergic receptor chronically treated with phenylephrine.
01
#LCRNCRNode / Date / Journal / AuthorLCSGCS
77100771 1998 CIRCULATION 98 (17): 737-737
Maurice JP; Hata JA; Shah AS; Wilson KH; McDonald PH; et al.
Global myocardial overpression of beta(2)-adrenergic receptors via intracoronary adenovirus delivery enhances in vivo contractility
11
77200772 1998 CIRCULATION 98 (17): 740-740
Iaccarino G; Smithwick A; Lefkowitz RJ; Koch WJ
G(beta g) inhibition attenuates vascular smooth muscle cell proliferation in vitro and in vivo
00
7731022773 1998 CIRCULATION 98 (17): 1783-1789
Iaccarino G; Tomhave ED; Lefkowitz RJ; Koch WJ
Reciprocal in vivo regulation of myocardial g protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade
11102
77400774 1998 FASEB JOURNAL 12 (4): A396-A396
Walker JKL; Peppel K; Lefkowitz RJ; Caron MG; Fisher JT
Altered cardiac chronotropic responses in beta ARK 2 knockout mice.
00
77500775 1998 FASEB JOURNAL 12 (5): A742-A742
Krueger KM; Claing A; Lefkowitz RJ
Mutagenesis of acidic residues in the beta(2)-adrenergic receptor abolishes the requirement of low pH for receptor dephosphorylation.
00
77600776 1998 HYPERTENSION 32 (3): 600-600
Iaccarino G; Trimarco B; Lefkowitz RJ; Koch WJ
beta adrenergic receptor kinase 1 (beta ARK1) expression in catecholamine induced cardiac hypertrophy
00
77700777 1998 HYPERTENSION 32 (3): 631-631
Anderson KM; Eckhart AD; Willette RN; Lefkowitz RJ; Koch WJ
Longitudinal evaluation of the myocardial beta-adrenergic system in spontaneously hypertensive heart failure (SHHF/Mcc-fa(C)P) rats
00
7781129778 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (2): 685-688
Daaka Y; Luttrell LM; Ahn S; Della Rocca GJ; Ferguson SSG; et al.
Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
19289
7791450779 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (20): 12316-12324
Pitcher JA; Hall RA; Daaka Y; Zhang J; Ferguson SSG; et al.
The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin
1070
780127780 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (28): 17749-17755
Snow BE; Hall RA; Krumins AM; Brothers GM; Bouchard D; et al.
GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain
0107
#LCRNCRNode / Date / Journal / AuthorLCSGCS
7811026781 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (29): 18180-18184
Rockman HA; Choi DJ; Akhter SA; Jaber M; Giros B; et al.
Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice
1663
7822247782 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (30): 18677-18680
Lefkowitz RJ
G protein-coupled receptors III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization
42539
783836783 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (32): 20653-20657
Freeman JLR; De La Cruz EM; Pollard TD; Lefkowitz RJ; Pitcher JA
Regulation of G protein-coupled receptor kinase 5 (GRK5) by actin
325
7841031784 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (48): 31640-31643
Lin FT; Daaka Y; Lefkowitz RJ
beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor
950
785320785 1998 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 30 (5): 1037-1045
Gaballa MA; Peppel K; Lefkowitz RJ; Aguirre M; Dolber PC; et al.
Enhanced vasorelaxation by overexpression of beta(2)-adrenergic receptors in large arteries
117
786223786 1998 JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY 115 (3): 623-630
Kypson AP; Peppel K; Akhter SA; Lilly RE; Glower DD; et al.
Ex vivo adenovirus-mediated gene transfer to the adult rat heart
323
787430787 1998 NATURE 392 (6676): 626-630
Hall RA; Premont RT; Chow CW; Blitzer JT; Pitcher JA; et al.
The beta(2)-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
14291
78800788 1998 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 358 (1): R7-R7
Lefkowitz RJ
New paradigms for G protein-coupled receptor signaling and desensitization.
00
789832789 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (12): 7000-7005
Rockman HA; Chien KR; Choi DJ; Iaccarino G; Hunter JJ; et al.
Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice
19199
790224790 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (15): 8496-8501
Hall RA; Ostedgaard LS; Premont RT; Blitzer JT; Rahman N; et al.
A C-terminal motif found in the beta(2)-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins
8220
#LCRNCRNode / Date / Journal / AuthorLCSGCS
7911029791 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (24): 14082-14087
Premont RT; Claing A; Vitale N; Freeman JLR; Pitcher JA; et al.
beta(2)-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
10116
792522792 1998 SCIENCE 280 (5363): 574-577
Akhter SA; Luttrell LM; Rockman HA; Iaccarino G; Lefkowitz RJ; et al.
Targeting the receptor-G(q) interface to inhibit in vivo pressure overload myocardial hypertrophy
5207
793540793 1998 SCIENCE 280 (5367): 1271-1274
Ford CE; Skiba NP; Bae HS; Daaka YH; Reuveny E; et al.
Molecular basis for interactions of G protein beta gamma subunits with effectors
1156
794629794 1999 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 276 (4): R1214-R1221
Walker JKL; Peppel K; Lefkowitz RJ; Caron RG; Fisher JT
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
826
7951122795 1999 CIRCULATION 100 (6): 648-653
Akhter SA; Eckhart AD; Rockman HA; Shotwell K; Lefkowitz RJ; et al.
In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function
538
79600796 1999 CIRCULATION 100 (18): 488-488
Xiao RP; Cheng HP; Zhou YY; Wang DG; Lefkowitz RJ; et al.
Muscarinic stimulation rescues beta(1)-adrenoceptors from desensitization induced by constitutively active beta(2)-adrenoceptors in cardiac myocytes
00
79700797 1999 CIRCULATION 100 (18): 493-493
Cross HR; Steenbergen C; Lefkowitz RJ; Murphy E
Expression of a beta ARK-1 inhibitor increases myocardial contractility without increasing susceptibility to ischemic injury
01
79800798 1999 CIRCULATION 100 (18): 494-494
Fentzke RC; Lin H; Korcarz CE; Lang RM; Koch W; et al.
Expression of beta-adrenergic receptor kinase 1 inhibitor fails to prevent the development or progression of heart failure in CREBA133 transgenic mice
00
79900799 1999 CIRCULATION 100 (18): 552-552
Harding VB; Rapacciuolo A; Mao L; Lefkowitz RJ; Rockman HA
beta ARK1 inhibition improves survival and cardiac function in a mouse model of severe cardiomyopathy
24
800642800 1999 CIRCULATION RESEARCH 84 (1): 43-52
Xiao RP; Avdonin P; Zhou YY; Chen HP; Akhter SA; et al.
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