HistCite - Initial sequencing and analysis of the human genome (Lander)

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#	Date / Author / Journal	LCS	GCS	LCR	CR
2101	259 Southan C A genomic perspective on human proteases as drug targets DRUG DISCOVERY TODAY. 2001 JUL 1; 6 (13): 681-688	4	44	1	42
2102	316 Broder S, Venter JC Genomics, science and medicine: the future is now DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S63-S64	0	0	2	11
2103	317 Debouck CM The genome: the beginning, not the end... and a means to many ends DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S65-S66	0	0	1	2
2104	318 Freiberg C Novel computational methods in anti-microbial target identification DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S72-S80	1	10	2	39
2105	319 Wahlestedt C Using genomics to understand the nervous system DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S81-S85	0	1	1	19
2106	320 Nef P Key animal models for the identification and validation of drug targets DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S91-S96	0	1	1	48
2107	321 Gurwitz D, Weizman A Animal models and human genome diversity: the pitfalls of inbred mice DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): 766-768	1	5	1	20
2108	322 Sanseau P Transgenic gene knockouts: a functional platform for the industry DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): 770-771	0	0	2	3
2109	337 [Anon] Human genome: bigger than we thought? DRUG DISCOVERY TODAY. 2001 AUG 15; 6 (16): 821-821	0	0	2	4
2110	402 Milburn J Beyond the genome: turning data into knowledge DRUG DISCOVERY TODAY. 2001 SEP 1; 6 (17): 881-+	0	1	2	2
#	Date / Author / Journal	LCS	GCS	LCR	CR
2111	492 Maggio ET, Ramnarayan K Recent developments in computational proteomics DRUG DISCOVERY TODAY. 2001 OCT 1; 6 (19): 996-1004	2	11	2	30
2112	705 Beck S Genome acrobatics: understanding complex genomes DRUG DISCOVERY TODAY. 2001 DEC 1; 6 (23): 1181-1182	0	0	2	9
2113	712 Jhoti H Structural genomics: lessons to be learnt DRUG DISCOVERY TODAY. 2001 DEC 15; 6 (24): 1261-1262	0	2	1	1
2114	1036 Wise A, Gearing K, Rees S Target validation of G-protein coupled receptors DRUG DISCOVERY TODAY. 2002 FEB 15; 7 (4): 235-246	21	166	2	84
2115	1110 Olden K New opportunities in toxicology in the post-genomic era DRUG DISCOVERY TODAY. 2002 MAR 1; 7 (5): 273-276	0	4	2	14
2116	1111 Augen J The evolving role of information technology in the drug discovery process DRUG DISCOVERY TODAY. 2002 MAR 1; 7 (5): 315-323	1	23	3	37
2117	1123 Williamson AR Gene patents: are they socially acceptable monopolies, essential for drug discovery? - Reply DRUG DISCOVERY TODAY. 2002 MAR 15; 7 (6): 346-347	0	0	1	6
2118	1176 Palfreyman MG Human tissue in target identification and drug discovery DRUG DISCOVERY TODAY. 2002 APR 1; 7 (7): 407-409	0	2	2	3
2119	1192 Tornell J, Snaith M Transgenic systems in drug discovery: from target identification to humanized mice DRUG DISCOVERY TODAY. 2002 APR 15; 7 (8): 461-470	1	16	2	85
2120	1285 Swindells MB, Overington JP Prioritizing the proteome: identifying pharmaceutically relevant targets DRUG DISCOVERY TODAY. 2002 MAY 1; 7 (9): 516-521	0	12	3	36
#	Date / Author / Journal	LCS	GCS	LCR	CR
2121	1389 Stahura FL, Bajorath J Bio-and chemo-informatics beyond data management: crucial challenges and future opportunities DRUG DISCOVERY TODAY. 2002 JUN 1; 7 (11): S41-S47	1	9	8	44
2122	1390 Duckworth DM, Sanseau P In silico identification of novel therapeutic targets DRUG DISCOVERY TODAY. 2002 JUN 1; 7 (11): S64-S69	2	6	8	61
2123	1484 Zanders ED, Bailey DS, Dean PM Probes for chemical genomics by design DRUG DISCOVERY TODAY. 2002 JUL 1; 7 (13): 711-718	1	16	3	42
2124	1497 Chambers SP High-throughput protein expression for the post-genomic era DRUG DISCOVERY TODAY. 2002 JUL 15; 7 (14): 759-765	2	18	5	53
2125	1555 Templin MF, Stoll D, Schrenk M, Traub PC, Vohringer CF, et al. Protein microarray technology DRUG DISCOVERY TODAY. 2002 AUG 1; 7 (15): 815-822	3	56	2	55
2126	1638 Thompson JD Applications of antisense and siRNAs during preclinical drug development DRUG DISCOVERY TODAY. 2002 SEP 1; 7 (17): 912-917	1	27	3	49
2127	1650 Bailey SN, Wu RZ, Sabatini DM Applications of transfected cell microarrays in high-throughput drug discovery DRUG DISCOVERY TODAY. 2002 SEP 15; 7 (18): S113-S118	4	31	2	25
2128	1697 van Huijsduijnen RH, Bombrun A, Swinnen D Selecting protein tyrosine phosphatases as drug targets DRUG DISCOVERY TODAY. 2002 OCT 1; 7 (19): 1013-1019	3	89	4	72
2129	1859 Russ A, Stumm G, Augustin M, Sedlmeier R, Wattler S, et al. Random mutagenesis in the mouse as a tool in drug discovery DRUG DISCOVERY TODAY. 2002 DEC 1; 7 (23): 1175-1183	2	19	5	46
2130	2186 Barrett JC, Kawasaki ES Microarrays: the use of oligonucleotides and cDNA for the analysis of gene expression DRUG DISCOVERY TODAY. 2003 FEB 1; 8 (3): 134-141	4	58	6	76
#	Date / Author / Journal	LCS	GCS	LCR	CR
2131	2198 Chanda SK, Caldwell JS Fulfilling the promise: drug discovery in the post-genomic era DRUG DISCOVERY TODAY. 2003 FEB 15; 8 (4): 168-174	5	42	4	52
2132	2281 Torchilin VP, Lukyanov AN Peptide and protein drug delivery to and into tumors: challenges and solutions DRUG DISCOVERY TODAY. 2003 MAR 15; 8 (6): 259-266	1	73	2	80
2133	2587 Milligan G High-content assays for ligand regulation of G-protein-coupled receptors DRUG DISCOVERY TODAY. 2003 JUL 1; 8 (13): 579-585	1	47	4	60
2134	2745 Cacace A, Banks M, Spicer T, Civoli F, Watson J An ultra-HTS process for the identification of small molecule modulators of orphan G-protein-coupled receptors DRUG DISCOVERY TODAY. 2003 SEP 1; 8 (17): 785-792	3	20	3	42
2135	2950 Brown D, Superti-Furga G Rediscovering the sweet spot in drug discovery DRUG DISCOVERY TODAY. 2003 DEC 1; 8 (23): 1067-1077	2	41	8	42
2136	3207 Jeffery DA, Bogyo M Chemical proteomics and its application to drug discovery DRUG DISCOVERY TODAY. 2004 JAN 15; 9 (2): S19-S26	0	3	7	47
2137	3208 Edwards AM, Kus B, Jansen R, Greenbaum D, Greenblatt J, et al. Bridging structural biology and genomics: assessing protein interaction data with known complexes DRUG DISCOVERY TODAY. 2004 JAN 15; 9 (2): S32-S40	0	0	3	40
2138	3209 Hegde PS, White IR, Debouck C Interplay of transcriptomics and proteomics DRUG DISCOVERY TODAY. 2004 JAN 15; 9 (2): S53-S56	0	1	2	33
2139	3643 Savage SA, Chanock SJ Using germ-line genetic variation to investigate and treat cancer DRUG DISCOVERY TODAY. 2004 JUL 15; 9 (14): 610-618	0	5	11	79
2140	3821 Ziegelbauer K, Farquhar R Strategic alliance management: lessons learned from the Bayer-Millennium collaboration DRUG DISCOVERY TODAY. 2004 OCT 15; 9 (20): 864-868	0	4	2	13
#	Date / Author / Journal	LCS	GCS	LCR	CR
2141	3885 Hemmerich S, Verdugo D, Rath VL Strategies for drug discovery by targeting sulfation pathways DRUG DISCOVERY TODAY. 2004 NOV 15; 9 (22): 967-975	0	15	2	60
2142	4226 Roses AD, Burns DK, Chissoe S, Middleton L, Jean PS Disease-specific target selection: a critical first step down the right road DRUG DISCOVERY TODAY. 2005 FEB 1; 10 (3): 177-189	0	28	7	59
2143	4548 Betz UAK How many genomics targets can a portfolio afford? DRUG DISCOVERY TODAY. 2005 AUG 1; 10 (15): 1057-1063	0	14	4	31
2144	4712 Ofran Y, Punta M, Schneider R, Rost B Beyond annotation transfer by homology: novel protein-function prediction methods to assist drug discovery DRUG DISCOVERY TODAY. 2005 NOV 1; 10 (21-24): 1475-1482	1	34	3	81
2145	5090 Autelitano DJ, Rajic A, Smith AI, Berndt MC, Ilag LL, et al. The cryptome: a subset of the proteome, comprising cryptic peptides with distinct bioactivities DRUG DISCOVERY TODAY. 2006 APR; 11 (7-8): 306-314	2	10	3	83
2146	5214 Schlyer S, Horuk R I want a new drug: G-protein-coupled receptors in drug development DRUG DISCOVERY TODAY. 2006 JUN; 11 (11-12): 481-493	2	50	5	91
2147	5409 Harris CJ, Stevens AP Chemogenomics: structuring the drug discovery process to gene families DRUG DISCOVERY TODAY. 2006 OCT; 11 (19-20): 880-888	0	18	8	49
2148	5632 Howe TJ, Mahieu G, Marichal P, Tabruyn T, Vugts P Data reduction and representation in drug discovery DRUG DISCOVERY TODAY. 2007 JAN; 12 (1-2): 45-53	0	7	3	28
2149	5890 Muzzi A, Masignani V, Rappuoli R The pan-genome: towards a knowledge-based discovery of novel targets for vaccines and antibacterials DRUG DISCOVERY TODAY. 2007 JUN; 12 (11-12): 429-439	0	20	2	87
2150	6116 Prodromou C, Sawa R, Driscoll PC DNA fragmentation-based combinatorial approaches to soluble protein expression Part I. Generating DNA fragment libraries DRUG DISCOVERY TODAY. 2007 NOV; 12 (21-22): 931-938	0	3	6	53
#	Date / Author / Journal	LCS	GCS	LCR	CR
2151	6555 Strausberg RL, Levy S, Rogers YH Emerging DNA sequencing technologies for human genomic medicine DRUG DISCOVERY TODAY. 2008 JUL; 13 (13-14): 569-577	1	10	4	69
2152	6603 Stumpp MT, Binz HK, Amstutz P DARPins: A new generation of protein therapeutics DRUG DISCOVERY TODAY. 2008 AUG; 13 (15-16): 695-701	0	4	4	44
2153	2920 Edwards RJ, Boobis AR, Davies DS A strategy for investigating the CYP superfamily using targeted antibodies is a paradigm for functional genomic studies DRUG METABOLISM AND DISPOSITION. 2003 DEC; 31 (12): 1476-1480	0	8	1	33
2154	4735 Girault I, Rougier N, Christophe C, Lidereau R, Beaune P, et al. Simultaneous measurement of 23 isoforms from the human cytochrome p450 families 1 to 3 by quantitative reverse transcriptase-polymerase chain reaction DRUG METABOLISM AND DISPOSITION. 2005 DEC; 33 (12): 1803-1810	0	13	2	40
2155	4047 Chowbay B, Zhou SF, Lee EJD An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters: Experience in Singapore DRUG METABOLISM REVIEWS. 2005; 37 (2): 327-378	0	38	4	384
2156	4048 Boukouvala S, Fakis G Arylamine N-acetyltransferases: What we learn from genes and genomes DRUG METABOLISM REVIEWS. 2005; 37 (3): 511-564	1	47	5	340
2157	2378 Gant TW Application of toxicogenomics in drug development DRUG NEWS & PERSPECTIVES. 2003 MAY; 16 (4): 217-221	0	4	2	22
2158	5633 Prous J, Khurdayan VK The story so far in R&D DRUG NEWS & PERSPECTIVES. 2007 JAN-FEB; 20 (1): 7-15	0	1	1	7
2159	1146 Ashton GHS, McGrath JA, South AP Strategies to identify disease genes DRUGS OF TODAY. 2002 APR; 38 (4): 235-244	0	4	5	44
2160	2629 Avraham KB Mouse models for deafness: Lessons for the human inner ear and hearing loss EAR AND HEARING. 2003 AUG; 24 (4): 332-341	2	15	3	76
#	Date / Author / Journal	LCS	GCS	LCR	CR
2161	4478 McGrath JJ, Keeping D, Saha S, Chant DC, Lieberman DE, et al. Seasonal fluctuations in birth weight and neonatal limb length; does prenatal vitamin D influence neonatal size and shape? EARLY HUMAN DEVELOPMENT. 2005 JUL; 81 (7): 609-618	0	11	2	55
2162	7319 McEvoy BP, Visscher PM Genetics of human height ECONOMICS & HUMAN BIOLOGY. 2009 DEC; 7 (3): 294-306	0	0	4	76
2163	546 Mitnik L, Novotny M, Felten C, Buonocore S, Koutny L, et al. Recent advances in DNA sequencing by capillary and microdevice electrophoresis ELECTROPHORESIS. 2001 NOV; 22 (19): 4104-4117	3	33	2	106
2164	975 Werhahn W, Braun HP Biochemical dissection of the mitochondrial proteome from Arabidopsis thaliana by three-dimensional gel electrophoresis ELECTROPHORESIS. 2002 FEB; 23 (4): 640-646	2	55	2	28
2165	1222 He H, Buchholz BA, Kotler L, Miller AW, Barron AE, et al. DNA sequencing with hydrophilic and hydrophobic polymers at elevated column temperatures ELECTROPHORESIS. 2002 MAY; 23 (10): 1421-1428	1	18	1	37
2166	1223 Ronai Z, Guttman A, Nemoda Z, Gervai J, Sasvari-Szekely M Direct haplotype detection of adjacent polymorphic sites in the regulatory region of the dopamine D4 receptor (DRD4) gene ELECTROPHORESIS. 2002 MAY; 23 (10): 1512-1516	0	5	1	29
2167	1525 Tseng WL, Lin YW, Chen KC, Chang HT DNA analysis on microfabricated electrophoretic devices with bubble cells ELECTROPHORESIS. 2002 AUG; 23 (15): 2477-2484	0	13	2	55
2168	1592 Kotler L, He H, Miller AW, Karger BL DNA sequencing of close to 1000 bases in 40 minutes by capillary electrophoresis using dimethyl sulfoxide and urea as denaturants in replaceable linear polyacrylamide solutions ELECTROPHORESIS. 2002 SEP; 23 (17): 3062-3070	3	23	3	45
2169	3663 Murray J, Marusich MF, Capaldi RA, Aggeler R Focused proteomics: Monoclonal antibody-based isolation of the oxidative phosphorylation machinery and detection of phosphoproteins using a fluorescent phosphoprotein gel stain ELECTROPHORESIS. 2004 AUG; 25 (15): 2520-2525	0	22	2	24
2170	4132 Kozlowski P, Krzyzosiak WJ Structural factors determining DNA length limitations in conformation-sensitive mutation detection methods ELECTROPHORESIS. 2005 JAN; 26 (1): 71-81	1	7	1	55
#	Date / Author / Journal	LCS	GCS	LCR	CR
2171	4133 Meagher RJ, Won JI, McCormick LC, Nedelcu S, Bertrand MM, et al. End-labeled free-solution electrophoresis of DNA ELECTROPHORESIS. 2005 JAN; 26 (2): 331-350	3	30	2	44
2172	4628 Kato M, Gyoten Y, Sakai-Kato K, Nakajima T, Toyo'oka T Analysis of amino acids and proteins using a poly(methyl methacrylate) microfluidic system ELECTROPHORESIS. 2005 OCT; 26 (19): 3682-3688	1	15	2	37
2173	4909 Babu S, Song EJ, Babar SME, Wi MH, Yoo YS Capillary electrophoresis at the omics level: Towards systems biology ELECTROPHORESIS. 2006 JAN; 27 (1): 97-110	0	8	6	186
2174	5022 Godde R, Akkad DA, Arning L, Dekomien G, Herchenbach J, et al. Electrophoresis of DNA in human genetic diagnostics - state-of-the-art, alternatives and future prospects ELECTROPHORESIS. 2006 MAR; 27 (5-6): 939-946	0	10	5	79
2175	5410 Fredlake CP, Hert DG, Mardis ER, Barron AE What is the future of electrophoresis in large-scale genomic sequencing? ELECTROPHORESIS. 2006 OCT; 27 (19): 3689-3702	8	23	19	112
2176	5411 Olejniczak M, Krzyzosiak WJ Genotyping of simple sequence repeats - factors implicated in shadow band generation revisited ELECTROPHORESIS. 2006 OCT; 27 (19): 3724-3734	0	5	2	58
2177	5492 Szantai E, Guttman A Genotyping with microfluidic devices ELECTROPHORESIS. 2006 DEC; 27 (24): 4896-4903	0	12	3	49
2178	6762 Hert DG, Fredlake CP, Barron AE Advantages and limitations of next-generation sequencing technologies: A comparison of electrophoresis and non-electrophoresis methods ELECTROPHORESIS. 2008 DEC; 29 (23): 4618-4626	0	4	19	92
2179	6763 Fredlake CP, Hert DG, Root BE, Barron AE Polymer systems designed specifically for DNA sequencing by microchip electrophoresis: A comparison with commercially available materials ELECTROPHORESIS. 2008 DEC; 29 (23): 4652-4662	1	1	12	46
2180	6764 Hert DG, Fredlake CP, Barron AE DNA sequencing by microchip electrophoresis using mixtures of high-and low-molar mass poly(N,N-dimethylacrylamide) matrices ELECTROPHORESIS. 2008 DEC; 29 (23): 4663-4668	0	0	11	27
#	Date / Author / Journal	LCS	GCS	LCR	CR
2181	6765 Root BE, Hammock ML, Barron AE Thermoresponsive N-alkoxyalkylacrylamide polymers as a sieving matrix for high-resolution DNA separations on a microfluidic chip ELECTROPHORESIS. 2008 DEC; 29 (23): 4677-4683	0	0	4	16
2182	6766 Kumagai H, Utsunomiya S, Nakamura S, Yamamoto R, Harada A, et al. Large-scale microfabricated channel plates for high-throughput, fully automated DNA sequencing ELECTROPHORESIS. 2008 DEC; 29 (23): 4723-4732	0	1	10	35
2183	6767 Huska D, Hubalek J, Adam V, Kizek R Miniaturized electrochemical detector as a tool for detection of DNA amplified by PCR ELECTROPHORESIS. 2008 DEC; 29 (24): 4964-4971	0	5	1	50
2184	7083 Forster RE, Hert DG, Chiesl TN, Fredlake CP, Barron AE DNA migration mechanism analyses for applications in capillary and microchip electrophoresis ELECTROPHORESIS. 2009 JUN; 30 (12): 2014-2024	0	0	8	75
2185	7084 Root BE, Zhang B, Barron AE Size-based protein separations by microchip electrophoresis using an acid-labile surfactant as a replacement for SDS ELECTROPHORESIS. 2009 JUN; 30 (12): 2117-2122	0	0	3	37
2186	404 Tutt A, Bertwistle D, Valentine J, Gabriel A, Swift S, et al. Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences EMBO JOURNAL. 2001 SEP 3; 20 (17): 4704-4716	6	159	1	61
2187	405 Le Hir H, Gatfield D, Izaurralde E, Moore MJ The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay EMBO JOURNAL. 2001 SEP 3; 20 (17): 4987-4997	9	258	1	43
2188	493 Betts MJ, Guigo R, Agarwal P, Russell RB Exon structure conservation despite low sequence similarity: a relic of dramatic events in evolution? EMBO JOURNAL. 2001 OCT 1; 20 (19): 5354-5360	6	31	1	31
2189	1020 Takahashi H, Fujiwara H Transplantation of target site specificity by swapping the endonuclease domains of two LINEs EMBO JOURNAL. 2002 FEB 1; 21 (3): 408-417	15	34	1	51
2190	1556 Skjerpen CS, Nilsen T, Wesche J, Olsnes S Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity EMBO JOURNAL. 2002 AUG 1; 21 (15): 4058-4069	3	30	1	48
#	Date / Author / Journal	LCS	GCS	LCR	CR
2191	1777 Cost GJ, Feng QH, Jacquier A, Boeke JD Human L1 element target-primed reverse transcription in vitro EMBO JOURNAL. 2002 NOV 1; 21 (21): 5899-5910	81	109	5	52
2192	1782 Hou VC, Lersch R, Gee SL, Ponthier JL, Lo AJ, et al. Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch EMBO JOURNAL. 2002 NOV 15; 21 (22): 6195-6204	6	41	2	66
2193	2206 Jin Y, Suzuki H, Maegawa S, Endo H, Sugano S, et al. A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG EMBO JOURNAL. 2003 FEB 17; 22 (4): 905-912	9	78	4	45
2194	2422 Eichinger L, Noegel AA Crawling into a new era - the Dictyostelium genome project EMBO JOURNAL. 2003 MAY 1; 22 (9): 1941-1946	1	19	4	31
2195	2423 Corda D, Di Girolamo M Functional aspects of protein mono-ADP-ribosylation EMBO JOURNAL. 2003 MAY 1; 22 (9): 1953-1958	0	78	3	50
2196	2807 Bird AJ, McCall K, Kramer M, Blankman E, Winge DR, et al. Zinc fingers can act as Zn2+ sensors to regulate transcriptional activation domain function EMBO JOURNAL. 2003 OCT 1; 22 (19): 5137-5146	3	33	1	45
2197	2822 Hoffmann A, Leung TH, Baltimore D Genetic analysis of NF-kappa B/Rel transcription factors defines functional specificities EMBO JOURNAL. 2003 OCT 15; 22 (20): 5530-5539	1	130	1	52
2198	4243 Martens JHA, O'Sullivan RJ, Braunschweig U, Opravil S, Radolf M, et al. The profile of repeat-associated histone lysine methylation states in the mouse epigenome EMBO JOURNAL. 2005 FEB 23; 24 (4): 800-812	17	171	9	65
2199	5060 Soares LMM, Valcarcel J The expanding transcriptome: the genome as the 'Book of Sand' EMBO JOURNAL. 2006 MAR 8; 25 (5): 923-931	4	33	18	107
2200	6543 Chen LL, DeCerbo JN, Carmichael GG Alu element-mediated gene silencing EMBO JOURNAL. 2008 JUN 18; 27 (12): 1694-1705	4	17	10	47

Date / Author / Journal

2101

A genomic perspective on human proteases as drug targets

DRUG DISCOVERY TODAY. 2001 JUL 1; 6 (13): 681-688

2102

316 Broder S, Venter JC

Genomics, science and medicine: the future is now

DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S63-S64

2103

317 Debouck CM

The genome: the beginning, not the end... and a means to many ends

DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S65-S66

2104

318 Freiberg C

Novel computational methods in anti-microbial target identification

DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S72-S80

2105

319 Wahlestedt C

Using genomics to understand the nervous system

DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S81-S85

2106

320 Nef P

Key animal models for the identification and validation of drug targets

DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): S91-S96

2107

321 Gurwitz D, Weizman A

Animal models and human genome diversity: the pitfalls of inbred mice

DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): 766-768

2108

322 Sanseau P

Transgenic gene knockouts: a functional platform for the industry

DRUG DISCOVERY TODAY. 2001 AUG 1; 6 (15): 770-771

2109

337 [Anon]

Human genome: bigger than we thought?

DRUG DISCOVERY TODAY. 2001 AUG 15; 6 (16): 821-821

2110

402 Milburn J

Beyond the genome: turning data into knowledge

DRUG DISCOVERY TODAY. 2001 SEP 1; 6 (17): 881-+

Date / Author / Journal

LCS

GCS

LCR

2111

492 Maggio ET, Ramnarayan K

Recent developments in computational proteomics

DRUG DISCOVERY TODAY. 2001 OCT 1; 6 (19): 996-1004

2112

705 Beck S

Genome acrobatics: understanding complex genomes

DRUG DISCOVERY TODAY. 2001 DEC 1; 6 (23): 1181-1182

2113

712 Jhoti H

Structural genomics: lessons to be learnt

DRUG DISCOVERY TODAY. 2001 DEC 15; 6 (24): 1261-1262

2114

1036 Wise A, Gearing K, Rees S

Target validation of G-protein coupled receptors

DRUG DISCOVERY TODAY. 2002 FEB 15; 7 (4): 235-246

166

2115

1110 Olden K

New opportunities in toxicology in the post-genomic era

DRUG DISCOVERY TODAY. 2002 MAR 1; 7 (5): 273-276

2116

1111 Augen J

The evolving role of information technology in the drug discovery process

DRUG DISCOVERY TODAY. 2002 MAR 1; 7 (5): 315-323

2117

1123 Williamson AR

Gene patents: are they socially acceptable monopolies, essential for drug discovery? - Reply

DRUG DISCOVERY TODAY. 2002 MAR 15; 7 (6): 346-347

2118

1176 Palfreyman MG

Human tissue in target identification and drug discovery

DRUG DISCOVERY TODAY. 2002 APR 1; 7 (7): 407-409

2119

1192 Tornell J, Snaith M

Transgenic systems in drug discovery: from target identification to humanized mice

DRUG DISCOVERY TODAY. 2002 APR 15; 7 (8): 461-470

2120

1285 Swindells MB, Overington JP

Prioritizing the proteome: identifying pharmaceutically relevant targets

DRUG DISCOVERY TODAY. 2002 MAY 1; 7 (9): 516-521

Date / Author / Journal

LCS

GCS

LCR

2121

1389 Stahura FL, Bajorath J

Bio-and chemo-informatics beyond data management: crucial challenges and future opportunities

DRUG DISCOVERY TODAY. 2002 JUN 1; 7 (11): S41-S47

2122

1390 Duckworth DM, Sanseau P

In silico identification of novel therapeutic targets

DRUG DISCOVERY TODAY. 2002 JUN 1; 7 (11): S64-S69

2123

1484 Zanders ED, Bailey DS, Dean PM

Probes for chemical genomics by design

DRUG DISCOVERY TODAY. 2002 JUL 1; 7 (13): 711-718

2124

1497 Chambers SP

High-throughput protein expression for the post-genomic era

DRUG DISCOVERY TODAY. 2002 JUL 15; 7 (14): 759-765

2125

1555 Templin MF, Stoll D, Schrenk M, Traub PC, Vohringer CF, et al.

Protein microarray technology

DRUG DISCOVERY TODAY. 2002 AUG 1; 7 (15): 815-822

2126

1638 Thompson JD

Applications of antisense and siRNAs during preclinical drug development

DRUG DISCOVERY TODAY. 2002 SEP 1; 7 (17): 912-917

2127

1650 Bailey SN, Wu RZ, Sabatini DM

Applications of transfected cell microarrays in high-throughput drug discovery

DRUG DISCOVERY TODAY. 2002 SEP 15; 7 (18): S113-S118

2128

1697 van Huijsduijnen RH, Bombrun A, Swinnen D

Selecting protein tyrosine phosphatases as drug targets

DRUG DISCOVERY TODAY. 2002 OCT 1; 7 (19): 1013-1019

2129

1859 Russ A, Stumm G, Augustin M, Sedlmeier R, Wattler S, et al.

Random mutagenesis in the mouse as a tool in drug discovery

DRUG DISCOVERY TODAY. 2002 DEC 1; 7 (23): 1175-1183

2130

2186 Barrett JC, Kawasaki ES

Microarrays: the use of oligonucleotides and cDNA for the analysis of gene expression

DRUG DISCOVERY TODAY. 2003 FEB 1; 8 (3): 134-141

Date / Author / Journal

LCS

GCS

LCR

2131

2198 Chanda SK, Caldwell JS

Fulfilling the promise: drug discovery in the post-genomic era

DRUG DISCOVERY TODAY. 2003 FEB 15; 8 (4): 168-174

2132

2281 Torchilin VP, Lukyanov AN

Peptide and protein drug delivery to and into tumors: challenges and solutions

DRUG DISCOVERY TODAY. 2003 MAR 15; 8 (6): 259-266

2133

2587 Milligan G

High-content assays for ligand regulation of G-protein-coupled receptors

DRUG DISCOVERY TODAY. 2003 JUL 1; 8 (13): 579-585

2134

2745 Cacace A, Banks M, Spicer T, Civoli F, Watson J

An ultra-HTS process for the identification of small molecule modulators of orphan G-protein-coupled receptors

DRUG DISCOVERY TODAY. 2003 SEP 1; 8 (17): 785-792

2135

2950 Brown D, Superti-Furga G

Rediscovering the sweet spot in drug discovery

DRUG DISCOVERY TODAY. 2003 DEC 1; 8 (23): 1067-1077

2136

3207 Jeffery DA, Bogyo M

Chemical proteomics and its application to drug discovery

DRUG DISCOVERY TODAY. 2004 JAN 15; 9 (2): S19-S26

2137

3208 Edwards AM, Kus B, Jansen R, Greenbaum D, Greenblatt J, et al.

Bridging structural biology and genomics: assessing protein interaction data with known complexes

DRUG DISCOVERY TODAY. 2004 JAN 15; 9 (2): S32-S40

2138

3209 Hegde PS, White IR, Debouck C

Interplay of transcriptomics and proteomics

DRUG DISCOVERY TODAY. 2004 JAN 15; 9 (2): S53-S56

2139

3643 Savage SA, Chanock SJ

Using germ-line genetic variation to investigate and treat cancer

DRUG DISCOVERY TODAY. 2004 JUL 15; 9 (14): 610-618

2140

3821 Ziegelbauer K, Farquhar R

Strategic alliance management: lessons learned from the Bayer-Millennium collaboration

DRUG DISCOVERY TODAY. 2004 OCT 15; 9 (20): 864-868

Date / Author / Journal

LCS

GCS

LCR

2141

3885 Hemmerich S, Verdugo D, Rath VL

Strategies for drug discovery by targeting sulfation pathways

DRUG DISCOVERY TODAY. 2004 NOV 15; 9 (22): 967-975

2142

4226 Roses AD, Burns DK, Chissoe S, Middleton L, Jean PS

Disease-specific target selection: a critical first step down the right road

DRUG DISCOVERY TODAY. 2005 FEB 1; 10 (3): 177-189

2143

4548 Betz UAK

How many genomics targets can a portfolio afford?

DRUG DISCOVERY TODAY. 2005 AUG 1; 10 (15): 1057-1063

2144

4712 Ofran Y, Punta M, Schneider R, Rost B

Beyond annotation transfer by homology: novel protein-function prediction methods to assist drug discovery

DRUG DISCOVERY TODAY. 2005 NOV 1; 10 (21-24): 1475-1482

2145

5090 Autelitano DJ, Rajic A, Smith AI, Berndt MC, Ilag LL, et al.

The cryptome: a subset of the proteome, comprising cryptic peptides with distinct bioactivities

DRUG DISCOVERY TODAY. 2006 APR; 11 (7-8): 306-314

2146

5214 Schlyer S, Horuk R

I want a new drug: G-protein-coupled receptors in drug development

DRUG DISCOVERY TODAY. 2006 JUN; 11 (11-12): 481-493

2147

5409 Harris CJ, Stevens AP

Chemogenomics: structuring the drug discovery process to gene families

DRUG DISCOVERY TODAY. 2006 OCT; 11 (19-20): 880-888

2148

5632 Howe TJ, Mahieu G, Marichal P, Tabruyn T, Vugts P

Data reduction and representation in drug discovery

DRUG DISCOVERY TODAY. 2007 JAN; 12 (1-2): 45-53

2149

5890 Muzzi A, Masignani V, Rappuoli R

The pan-genome: towards a knowledge-based discovery of novel targets for vaccines and antibacterials

DRUG DISCOVERY TODAY. 2007 JUN; 12 (11-12): 429-439

2150

6116 Prodromou C, Sawa R, Driscoll PC

DNA fragmentation-based combinatorial approaches to soluble protein expression Part I. Generating DNA fragment libraries

DRUG DISCOVERY TODAY. 2007 NOV; 12 (21-22): 931-938

Date / Author / Journal

LCS

GCS

LCR

2151

6555 Strausberg RL, Levy S, Rogers YH

Emerging DNA sequencing technologies for human genomic medicine

DRUG DISCOVERY TODAY. 2008 JUL; 13 (13-14): 569-577

2152

6603 Stumpp MT, Binz HK, Amstutz P

DARPins: A new generation of protein therapeutics

DRUG DISCOVERY TODAY. 2008 AUG; 13 (15-16): 695-701

2153

2920 Edwards RJ, Boobis AR, Davies DS

A strategy for investigating the CYP superfamily using targeted antibodies is a paradigm for functional genomic studies

DRUG METABOLISM AND DISPOSITION. 2003 DEC; 31 (12): 1476-1480

2154

4735 Girault I, Rougier N, Christophe C, Lidereau R, Beaune P, et al.

Simultaneous measurement of 23 isoforms from the human cytochrome p450 families 1 to 3 by quantitative reverse transcriptase-polymerase chain reaction

DRUG METABOLISM AND DISPOSITION. 2005 DEC; 33 (12): 1803-1810

2155

4047 Chowbay B, Zhou SF, Lee EJD

An interethnic comparison of polymorphisms of the genes encoding drug-metabolizing enzymes and drug transporters: Experience in Singapore

DRUG METABOLISM REVIEWS. 2005; 37 (2): 327-378

384

2156

4048 Boukouvala S, Fakis G

Arylamine N-acetyltransferases: What we learn from genes and genomes

DRUG METABOLISM REVIEWS. 2005; 37 (3): 511-564

340

2157

2378 Gant TW

Application of toxicogenomics in drug development

DRUG NEWS & PERSPECTIVES. 2003 MAY; 16 (4): 217-221

2158

5633 Prous J, Khurdayan VK

The story so far in R&D

DRUG NEWS & PERSPECTIVES. 2007 JAN-FEB; 20 (1): 7-15

2159

1146 Ashton GHS, McGrath JA, South AP

Strategies to identify disease genes

DRUGS OF TODAY. 2002 APR; 38 (4): 235-244

2160

2629 Avraham KB

Mouse models for deafness: Lessons for the human inner ear and hearing loss

EAR AND HEARING. 2003 AUG; 24 (4): 332-341

Date / Author / Journal

LCS

GCS

LCR

2161

4478 McGrath JJ, Keeping D, Saha S, Chant DC, Lieberman DE, et al.

Seasonal fluctuations in birth weight and neonatal limb length; does prenatal vitamin D influence neonatal size and shape?

EARLY HUMAN DEVELOPMENT. 2005 JUL; 81 (7): 609-618

2162

7319 McEvoy BP, Visscher PM

Genetics of human height

ECONOMICS & HUMAN BIOLOGY. 2009 DEC; 7 (3): 294-306

2163

546 Mitnik L, Novotny M, Felten C, Buonocore S, Koutny L, et al.

Recent advances in DNA sequencing by capillary and microdevice electrophoresis

ELECTROPHORESIS. 2001 NOV; 22 (19): 4104-4117

106

2164

975 Werhahn W, Braun HP

Biochemical dissection of the mitochondrial proteome from Arabidopsis thaliana by three-dimensional gel electrophoresis

ELECTROPHORESIS. 2002 FEB; 23 (4): 640-646

2165

1222 He H, Buchholz BA, Kotler L, Miller AW, Barron AE, et al.

DNA sequencing with hydrophilic and hydrophobic polymers at elevated column temperatures

ELECTROPHORESIS. 2002 MAY; 23 (10): 1421-1428

2166

1223 Ronai Z, Guttman A, Nemoda Z, Gervai J, Sasvari-Szekely M

Direct haplotype detection of adjacent polymorphic sites in the regulatory region of the dopamine D4 receptor (DRD4) gene

ELECTROPHORESIS. 2002 MAY; 23 (10): 1512-1516

2167

1525 Tseng WL, Lin YW, Chen KC, Chang HT

DNA analysis on microfabricated electrophoretic devices with bubble cells

ELECTROPHORESIS. 2002 AUG; 23 (15): 2477-2484

2168

1592 Kotler L, He H, Miller AW, Karger BL

DNA sequencing of close to 1000 bases in 40 minutes by capillary electrophoresis using dimethyl sulfoxide and urea as denaturants in replaceable linear polyacrylamide solutions

ELECTROPHORESIS. 2002 SEP; 23 (17): 3062-3070

2169

3663 Murray J, Marusich MF, Capaldi RA, Aggeler R

Focused proteomics: Monoclonal antibody-based isolation of the oxidative phosphorylation machinery and detection of phosphoproteins using a fluorescent phosphoprotein gel stain

ELECTROPHORESIS. 2004 AUG; 25 (15): 2520-2525

2170

4132 Kozlowski P, Krzyzosiak WJ

Structural factors determining DNA length limitations in conformation-sensitive mutation detection methods

ELECTROPHORESIS. 2005 JAN; 26 (1): 71-81

Date / Author / Journal

LCS

GCS

LCR

2171

4133 Meagher RJ, Won JI, McCormick LC, Nedelcu S, Bertrand MM, et al.

End-labeled free-solution electrophoresis of DNA

ELECTROPHORESIS. 2005 JAN; 26 (2): 331-350

2172

4628 Kato M, Gyoten Y, Sakai-Kato K, Nakajima T, Toyo'oka T

Analysis of amino acids and proteins using a poly(methyl methacrylate) microfluidic system

ELECTROPHORESIS. 2005 OCT; 26 (19): 3682-3688

2173

4909 Babu S, Song EJ, Babar SME, Wi MH, Yoo YS

Capillary electrophoresis at the omics level: Towards systems biology

ELECTROPHORESIS. 2006 JAN; 27 (1): 97-110

186

2174

5022 Godde R, Akkad DA, Arning L, Dekomien G, Herchenbach J, et al.

Electrophoresis of DNA in human genetic diagnostics - state-of-the-art, alternatives and future prospects

ELECTROPHORESIS. 2006 MAR; 27 (5-6): 939-946

2175

5410 Fredlake CP, Hert DG, Mardis ER, Barron AE

What is the future of electrophoresis in large-scale genomic sequencing?

ELECTROPHORESIS. 2006 OCT; 27 (19): 3689-3702

112

2176

5411 Olejniczak M, Krzyzosiak WJ

Genotyping of simple sequence repeats - factors implicated in shadow band generation revisited

ELECTROPHORESIS. 2006 OCT; 27 (19): 3724-3734

2177

5492 Szantai E, Guttman A

Genotyping with microfluidic devices

ELECTROPHORESIS. 2006 DEC; 27 (24): 4896-4903

2178

6762 Hert DG, Fredlake CP, Barron AE

Advantages and limitations of next-generation sequencing technologies: A comparison of electrophoresis and non-electrophoresis methods

ELECTROPHORESIS. 2008 DEC; 29 (23): 4618-4626

2179

6763 Fredlake CP, Hert DG, Root BE, Barron AE

Polymer systems designed specifically for DNA sequencing by microchip electrophoresis: A comparison with commercially available materials

ELECTROPHORESIS. 2008 DEC; 29 (23): 4652-4662

2180

6764 Hert DG, Fredlake CP, Barron AE

DNA sequencing by microchip electrophoresis using mixtures of high-and low-molar mass poly(N,N-dimethylacrylamide) matrices

ELECTROPHORESIS. 2008 DEC; 29 (23): 4663-4668

Date / Author / Journal

LCS

GCS

LCR

2181

6765 Root BE, Hammock ML, Barron AE

Thermoresponsive N-alkoxyalkylacrylamide polymers as a sieving matrix for high-resolution DNA separations on a microfluidic chip

ELECTROPHORESIS. 2008 DEC; 29 (23): 4677-4683

2182

6766 Kumagai H, Utsunomiya S, Nakamura S, Yamamoto R, Harada A, et al.

Large-scale microfabricated channel plates for high-throughput, fully automated DNA sequencing

ELECTROPHORESIS. 2008 DEC; 29 (23): 4723-4732

2183

6767 Huska D, Hubalek J, Adam V, Kizek R

Miniaturized electrochemical detector as a tool for detection of DNA amplified by PCR

ELECTROPHORESIS. 2008 DEC; 29 (24): 4964-4971

2184

7083 Forster RE, Hert DG, Chiesl TN, Fredlake CP, Barron AE

DNA migration mechanism analyses for applications in capillary and microchip electrophoresis

ELECTROPHORESIS. 2009 JUN; 30 (12): 2014-2024

2185

7084 Root BE, Zhang B, Barron AE

Size-based protein separations by microchip electrophoresis using an acid-labile surfactant as a replacement for SDS

ELECTROPHORESIS. 2009 JUN; 30 (12): 2117-2122

2186

404 Tutt A, Bertwistle D, Valentine J, Gabriel A, Swift S, et al.

Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

EMBO JOURNAL. 2001 SEP 3; 20 (17): 4704-4716

159

2187

405 Le Hir H, Gatfield D, Izaurralde E, Moore MJ

The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

EMBO JOURNAL. 2001 SEP 3; 20 (17): 4987-4997

258

2188

493 Betts MJ, Guigo R, Agarwal P, Russell RB

Exon structure conservation despite low sequence similarity: a relic of dramatic events in evolution?

EMBO JOURNAL. 2001 OCT 1; 20 (19): 5354-5360

2189

1020 Takahashi H, Fujiwara H

Transplantation of target site specificity by swapping the endonuclease domains of two LINEs

EMBO JOURNAL. 2002 FEB 1; 21 (3): 408-417

2190

1556 Skjerpen CS, Nilsen T, Wesche J, Olsnes S

Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity

EMBO JOURNAL. 2002 AUG 1; 21 (15): 4058-4069

Date / Author / Journal

LCS

GCS

LCR

2191

1777 Cost GJ, Feng QH, Jacquier A, Boeke JD

Human L1 element target-primed reverse transcription in vitro

EMBO JOURNAL. 2002 NOV 1; 21 (21): 5899-5910

109

2192

1782 Hou VC, Lersch R, Gee SL, Ponthier JL, Lo AJ, et al.

Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch

EMBO JOURNAL. 2002 NOV 15; 21 (22): 6195-6204

2193

2206 Jin Y, Suzuki H, Maegawa S, Endo H, Sugano S, et al.

A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG

EMBO JOURNAL. 2003 FEB 17; 22 (4): 905-912

2194

2422 Eichinger L, Noegel AA

Crawling into a new era - the Dictyostelium genome project

EMBO JOURNAL. 2003 MAY 1; 22 (9): 1941-1946

2195

2423 Corda D, Di Girolamo M

Functional aspects of protein mono-ADP-ribosylation

EMBO JOURNAL. 2003 MAY 1; 22 (9): 1953-1958

2196

2807 Bird AJ, McCall K, Kramer M, Blankman E, Winge DR, et al.

Zinc fingers can act as Zn2+ sensors to regulate transcriptional activation domain function

EMBO JOURNAL. 2003 OCT 1; 22 (19): 5137-5146

2197

2822 Hoffmann A, Leung TH, Baltimore D

Genetic analysis of NF-kappa B/Rel transcription factors defines functional specificities

EMBO JOURNAL. 2003 OCT 15; 22 (20): 5530-5539

130

2198

4243 Martens JHA, O'Sullivan RJ, Braunschweig U, Opravil S, Radolf M, et al.

The profile of repeat-associated histone lysine methylation states in the mouse epigenome

EMBO JOURNAL. 2005 FEB 23; 24 (4): 800-812

171

2199

5060 Soares LMM, Valcarcel J

The expanding transcriptome: the genome as the 'Book of Sand'

EMBO JOURNAL. 2006 MAR 8; 25 (5): 923-931

107

2200

6543 Chen LL, DeCerbo JN, Carmichael GG

Alu element-mediated gene silencing

EMBO JOURNAL. 2008 JUN 18; 27 (12): 1694-1705

Initial sequencing and analysis of the human genome (Lander) The papers citing Lander ES, et al. "Initial sequencing and analysis of the human genome." NATURE. 2001 FEB 15; 409 (6822): 860-921	Historiographs	Glossary HistCite Guide About Grand Totals: LCS 38623, GCS 253809, CR 422506 Collection span: 2000 - 2010
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