HistCite - main: Papers by DE Koshland

Mon May 8 14:33:08 2006

Papers by DE Koshland

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# LCR NCR Node / Date / Journal / Author LCS GCS
101 5 37 432 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86 (15): 5683-5687
MOE GR; BOLLAG GE; KOSHLAND DE
TRANSMEMBRANE SIGNALING BY A CHIMERA OF THE ESCHERICHIA-COLI ASPARTATE RECEPTOR AND THE HUMAN INSULIN-RECEPTOR
10 50
102 4 36 117 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245 (1): 80-&
LONG CW; LEVITZKI A; KOSHLAND DE
SUBUNIT STRUCTURE AND SUBUNIT INTERACTIONS OF CYTIDINE TRIPHOSPHATE SYNTHETASE
7 72
103 5 36 217 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75 (8): 3659-3663
STOCK JB; KOSHLAND DE
PROTEIN METHYLESTERASE INVOLVED IN BACTERIAL SENSING
40 230
104 8 36 242 1980 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 77 (12): 7157-7161
WANG EA; KOSHLAND DE
RECEPTOR STRUCTURE IN THE BACTERIAL SENSING SYSTEM
33 124
105 16 36 273 1983 TRENDS IN NEUROSCIENCES 6 (4): 133-137
KOSHLAND DE
THE BACTERIUM AS A MODEL NEURON
1 12
106 3 36 278 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259 (15): 9646-9654
WALSH K; KOSHLAND DE
DETERMINATION OF FLUX THROUGH THE BRANCH POINT OF 2 METABOLIC CYCLES - THE TRICARBOXYLIC-ACID CYCLE AND THE GLYOXYLATE SHUNT
8 101
107 2 35 49 1962 JOURNAL OF BIOLOGICAL CHEMISTRY 237 (8): 2493-&
RAY WJ; KOSHLAND DE
IDENTIFICATION OF AMINO ACIDS INVOLVED IN PHOSPHOGLUCOMUTASE ACTION
9 241
108 5 35 219 1979 BIOCHEMISTRY 18 (25): 5599-5605
ZUKIN RS; HARTIG PR; KOSHLAND DE
EFFECT OF AN INDUCED CONFORMATIONAL CHANGE ON THE PHYSICAL-PROPERTIES OF 2 CHEMOTACTIC RECEPTOR MOLECULES
2 22
109 0 35 397 1988 NATURE 331 (6156): 499-504
KOSHLAND DE; MITCHISON TJ; KIRSCHNER MW
POLEWARDS CHROMOSOME MOVEMENT DRIVEN BY MICROTUBULE DEPOLYMERIZATION INVITRO
0 225
110 5 35 575 1993 BIOCHEMISTRY 32 (36): 9302-9309
DEAN AM; KOSHLAND DE
KINETIC MECHANISM OF ESCHERICHIA-COLI ISOCITRATE DEHYDROGENASE
9 34
# LCR NCR Node / Date / Journal / Author LCS GCS
111 8 35 689 1996 PROTEIN SCIENCE 5 (2): 348-356
Zhang T; Koshland DE
Computational method for relative binding energies of enzyme-substrate complexes
0 28
112 11 35 713 2000 JOURNAL OF MOLECULAR BIOLOGY 295 (3): 377-385
Cherbavaz DB; Lee ME; Stroud RM; Koshland DE
Active site water molecules revealed in the 2.1 angstrom resolution structure of a site-directed mutant of isocitrate dehydrogenase
0 11
113 2 35 735 2004 BIOCHEMISTRY 43 (43): 13648-13656
Radisky ES; Kwan G; Lu CJK; Koshland DE
Binding, proteolytic, and crystallographic analyses of mutations at the protease-inhibitor interface of the subtilisin BPN '/chymotrypsin inhibitor 2 complex
1 3
114 1 34 6 1952 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 74 (9): 2286-2292
KOSHLAND DE
EFFECT OF CATALYSTS ON THE HYDROLYSIS OF ACETYL PHOSPHATE - NUCLEOPHILIC DISPLACEMENT MECHANISMS IN ENZYMATIC REACTIONS
5 170
115 3 34 15 1955 DISCUSSIONS OF THE FARADAY SOCIETY (20): 142-148
KOSHLAND DE
ISOTOPIC EXCHANGE CRITERIA FOR ENZYME MECHANISMS
0 7
116 4 34 191 1976 SCIENCE 193 (4251): 405-408
ZUKIN RS; KOSHLAND DE
MG2+,CA2+-DEPENDENT ADENOSINE-TRIPHOSPHATASE AS RECEPTOR FOR DIVALENT-CATIONS IN BACTERIAL SENSING
4 22
117 1 34 294 1985 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82 (11): 3577-3581
WALSH K; KOSHLAND DE
CHARACTERIZATION OF RATE-CONTROLLING STEPS INVIVO BY USE OF AN ADJUSTABLE EXPRESSION VECTOR
1 89
118 15 34 322 1986 JOURNAL OF BACTERIOLOGY 165 (1): 276-282
RUSSO AF; KOSHLAND DE
IDENTIFICATION OF THE TIP-ENCODED RECEPTOR IN BACTERIAL SENSING
0 10
119 3 34 469 1990 NEURON 5 (6): 875-880
MORIMOTO BH; KOSHLAND DE
INDUCTION AND EXPRESSION OF LONG-TERM AND SHORT-TERM NEUROSECRETORY POTENTIATION IN A NEURAL CELL-LINE
7 52
120 8 34 583 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268 (27): 19991-19997
MILLIGAN DL; KOSHLAND DE
PURIFICATION AND CHARACTERIZATION OF THE PERIPLASMIC DOMAIN OF THE ASPARTATE CHEMORECEPTOR
7 18
# LCR NCR Node / Date / Journal / Author LCS GCS
121 2 33 122 1970 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 66 (2): 445-&
STORM DR; KOSHLAND DE
A SOURCE FOR SPECIAL CATALYTIC POWER OF ENZYMES - ORBITAL STEERIN
8 163
122 2 33 196 1977 BIOCHEMISTRY 16 (3): 381-386
ZUKIN RS; STRANGE PG; HEAVEY LR; KOSHLAND DE
PROPERTIES OF GALACTOSE BINDING-PROTEIN OF SALMONELLA-TYPHIMURIUM AND ESCHERICHIA-COLI
7 47
123 7 33 216 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75 (6): 2820-2824
RUBIK BA; KOSHLAND DE
POTENTIATION, DESENSITIZATION, AND INVERSION OF RESPONSE IN BACTERIAL SENSING OF CHEMICAL STIMULI
15 52
124 10 33 227 1979 JOURNAL OF BACTERIOLOGY 140 (3): 798-804
INGOLIA TD; KOSHLAND DE
RESPONSE TO A METAL-ION CITRATE COMPLEX IN BACTERIAL SENSING
1 12
125 3 33 259 1982 QUARTERLY REVIEWS OF BIOPHYSICS 15 (3): 555-591
GOLDBETER A; KOSHLAND DE
SENSITIVITY AMPLIFICATION IN BIOCHEMICAL SYSTEMS
3 84
126 2 33 428 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264 (22): 12765-12771
MCFADDEN PN; MANDPE A; KOSHLAND DE
CALCIUM-INDEPENDENT AND LIPID-INDEPENDENT PROTEIN KINASE-C AUTOPHOSPHORYLATION - ACTIVATION BY LOW PH
0 26
127 2 33 487 1990 SCIENCE 249 (4967): 408-411
FLINT AJ; PALADINI RD; KOSHLAND DE
AUTOPHOSPHORYLATION OF PROTEIN KINASE-C AT 3-SEPARATED REGIONS OF ITS PRIMARY SEQUENCE
1 120
128 3 33 737 2005 BIOCHEMISTRY 44 (18): 6823-6830
Radisky ES; Lu CJK; Kwan G; Koshland DE
Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
0 0
129 5 32 118 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245 (2): 276-&
KIRTLEY ME; KOSHLAND DE
PROPERTIES OF RABBIT MUSCLE GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE LABELED WITH A REPORTER-GROUP
1 22
130 4 32 128 1971 BIOCHEMISTRY 10 (18): 3371-&
LEVITZKI A; STALLCUP WB; KOSHLAND DE
HALF-OF-SITES REACTIVITY AND CONFORMATIONAL STATES OF CYTIDINE TRIPHOSPHATE SYNTHETASE
12 205
# LCR NCR Node / Date / Journal / Author LCS GCS
131 10 32 184 1976 FEBS LETTERS 62: E47-E52
KOSHLAND DE
ROLE OF FLEXIBILITY IN SPECIFICITY, CONTROL AND EVOLUTION OF ENZYMES
0 28
132 10 32 277 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259 (12): 7719-7725
TERWILLIGER TC; KOSHLAND DE
SITES OF METHYL ESTERIFICATION AND DEAMINATION ON THE ASPARTATE RECEPTOR INVOLVED IN CHEMOTAXIS
19 78
133 6 32 576 1993 BIOCHEMISTRY 32 (36): 9310-9316
STODDARD BL; DEAN A; KOSHLAND DE
STRUCTURE OF ISOCITRATE DEHYDROGENASE WITH ISOCITRATE, NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE, AND CALCIUM AT 2.5-ANGSTROM RESOLUTION - A PSEUDO-MICHAELIS TERNARY COMPLEX
10 67
134 9 32 585 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90 (4): 1146-1153
STODDARD BL; KOSHLAND DE
MOLECULAR RECOGNITION ANALYZED BY DOCKING SIMULATIONS - THE ASPARTATE RECEPTOR AND ISOCITRATE DEHYDROGENASE FROM ESCHERICHIA-COLI
0 26
135 3 32 625 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269 (6): 4065-4069
MORIMOTO BH; KOSHLAND DE
CONDITIONAL ACTIVATION OF CAMP SIGNAL-TRANSDUCTION BY PROTEIN-KINASE-C - THE EFFECT OF PHORBOL ESTERS ON ADENYLYL-CYCLASE IN PERMEABILIZED AND INTACT-CELLS
0 31
136 9 32 626 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269 (15): 11054-11059
SHAPIRO MJ; KOSHLAND DE
MUTAGENIC STUDIES OF THE INTERACTION BETWEEN THE ASPARTATE RECEPTOR AND METHYLTRANSFERASE FROM ESCHERICHIA-COLI
9 27
137 15 32 657 1995 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 33 (23-24): 2375-2378
KOSHLAND DE
THE KEY-LOCK THEORY AND THE INDUCED FIT THEORY
0 110
138 4 31 11 1954 JOURNAL OF BIOLOGICAL CHEMISTRY 208 (1): 139-148
KOSHLAND DE; STEIN SS
CORRELATION OF BOND BREAKING WITH ENZYME SPECIFICITY - CLEAVAGE POINT OF INVERTASE
3 45
139 3 31 21 1956 JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY 47: 217-234
KOSHLAND DE
MOLECULAR GEOMETRY IN ENZYME ACTION
6 34
140 3 31 83 1966 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 56 (5): 1606-&
NEET KE; KOSHLAND DE
CONVERSION OF SERINE AT ACTIVE SITE OF SUBTILISIN TO CYSTEINE - A CHEMICAL MUTATION
2 147
# LCR NCR Node / Date / Journal / Author LCS GCS
141 4 31 190 1976 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73 (3): 762-766
STRANGE PG; KOSHLAND DE
RECEPTOR INTERACTIONS IN A SIGNALING SYSTEM - COMPETITION BETWEEN RIBOSE RECEPTOR AND GALACTOSE RECEPTOR IN CHEMOTAXIS RESPONSE
18 93
142 3 31 205 1977 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 74 (5): 1932-1936
ZUKIN RS; HARTIG PR; KOSHLAND DE
USE OF A DISTANT REPORTER GROUP AS EVIDENCE FOR A CONFORMATIONAL CHANGE IN A SENSORY RECEPTOR
4 66
143 6 31 240 1980 JOURNAL OF SUPRAMOLECULAR STRUCTURE 13 (3): 315-328
CLARKE S; SPARROW K; PANASENKO S; KOSHLAND DE
INVITRO METHYLATION OF BACTERIAL CHEMOTAXIS PROTEINS - CHARACTERIZATION OF PROTEIN METHYLTRANSFERASE ACTIVITY IN CRUDE EXTRACTS OF SALMONELLA-TYPHIMURIUM
5 32
144 11 31 246 1981 CELL 27 (1): 37-44
STOCK JB; MADERIS AM; KOSHLAND DE
BACTERIAL CHEMOTAXIS IN THE ABSENCE OF RECEPTOR CARBOXYLMETHYLATION
9 40
145 8 31 293 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260 (21): 1711-1718
MOWBRAY SL; FOSTER DL; KOSHLAND DE
PROTEOLYTIC FRAGMENTS IDENTIFIED WITH DOMAINS OF THE ASPARTATE CHEMORECEPTOR
19 60
146 14 31 393 1988 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 53: 11-17
KOSHLAND DE; SANDERS DA; WEIS RM
ROLES OF METHYLATION AND PHOSPHORYLATION IN THE BACTERIAL SENSING SYSTEM
0 6
147 8 31 679 1996 BIOCHEMISTRY 35 (9): 2854-2864
Brubaker MJ; Dyer DH; Stoddard B; Koshland DE
Synthesis, kinetics, and structural studies of a photolabile caged isocitrate: A catalytic trigger for isocitrate dehydrogenase
1 11
148 8 31 695 1997 BIOCHEMISTRY 36 (45): 13890-13896
FinerMoore J; Tsutakawa SE; Cherbavaz DB; LaPorte DC; Koshland DE; et al.
Access to phosphorylation in isocitrate dehydrogenase may occur by domain shifting
2 17
149 11 31 717 2001 BIOCHEMISTRY 40 (14): 4234-4241
Doyle SA; Beernink PT; Koshland DE
Structural basis for a change in substrate specificity: Crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP
0 8
150 3 30 91 1967 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 57 (6): 1670-&
FENSELAU A; KOENIG D; KOSHLAND DE; LATHAM HG; WEINER H
A SYSTEMATIC METHOD FOR INTRODUCING HEAVY ATOMS INTO A PROTEIN MOLECULE
0 6
# LCR NCR Node / Date / Journal / Author LCS GCS
151 2 30 248 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256 (9): 4640-4648
WANG JYJ; KOSHLAND DE
THE IDENTIFICATION OF DISTINCT PROTEIN-KINASES AND PHOSPHATASES IN THE PROKARYOTE SALMONELLA-TYPHIMURIUM
6 62
152 0 30 356 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262 (5): 2291-2297
MOCHLYROSEN D; KOSHLAND DE
DOMAIN-STRUCTURE AND PHOSPHORYLATION OF PROTEIN-KINASE-C
10 161
153 8 30 577 1993 BIOCHEMISTRY 32 (36): 9317-9322
STODDARD BL; KOSHLAND DE
STRUCTURE OF ISOCITRATE DEHYDROGENASE WITH ALPHA-KETOGLUTARATE AT 2.7-ANGSTROM RESOLUTION - CONFORMATIONAL-CHANGES INDUCED BY DECARBOXYLATION OF ISOCITRATE
9 38
154 6 30 621 1994 BIOCHEMISTRY 33 (12): 3457-3463
JEFFERY CJ; KOSHLAND DE
A SINGLE HYDROPHOBIC TO HYDROPHOBIC SUBSTITUTION IN THE TRANSMEMBRANE DOMAIN IMPAIRS ASPARTATE RECEPTOR FUNCTION
4 11
155 13 30 660 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270 (41): 24038-24042
CHEN XM; KOSHLAND DE
THE N-TERMINAL CYTOPLASMIC TAIL OF THE ASPARTATE RECEPTOR IS NOT ESSENTIAL IN SIGNAL-TRANSDUCTION OF BACTERIAL CHEMOTAXIS
1 11
156 3 29 51 1963 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 103 (2): 630-&
KOSHLAND DE
.1. ASPECTS OF 2-COMPONENT IMMUNOLOGY - PROPERTIES OF ACTIVE SITE OF ENZYMES
0 15
157 1 29 159 1974 BIOCHEMISTRY 13 (22): 4473-4478
AKSAMIT RR; KOSHLAND DE
IDENTIFICATION OF RIBOSE BINDING-PROTEIN AS RECEPTOR FOR RIBOSE CHEMOTAXIS IN SALMONELLA-TYPHIMURIUM
19 83
158 11 29 186 1976 FEDERATION PROCEEDINGS 35 (10): 2104-2111
KOSHLAND DE
EVOLUTION OF FUNCTION IN ENZYMES
3 27
159 3 29 189 1976 NATURE 262 (5568): 467-471
SPUDICH JL; KOSHLAND DE
NON-GENETIC INDIVIDUALITY - CHANCE IN SINGLE CELL
7 109
160 5 29 192 1976 TRENDS IN BIOCHEMICAL SCIENCES 1 (1): 1-3
KOSHLAND DE
BACTERIAL CHEMOTAXIS AS A SIMPLE MODEL FOR A SENSORY SYSTEM
1 3
# LCR NCR Node / Date / Journal / Author LCS GCS
161 10 29 281 1984 METHODS IN ENZYMOLOGY 106: 310-321
BINSTOCK J; CLARKE S; KOSHLAND DE
THE PROTEIN CARBOXYLMETHYLTRANSFERASE INVOLVED IN ESCHERICHIA-COLI AND SALMONELLA-TYPHIMURIUM CHEMOTAXIS
0 0
162 9 29 292 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260 (21): 1706-1710
FOSTER DL; MOWBRAY SL; JAP BK; KOSHLAND DE
PURIFICATION AND CHARACTERIZATION OF THE ASPARTATE CHEMORECEPTOR
21 57
163 7 29 323 1986 JOURNAL OF BACTERIOLOGY 165 (3): 958-963
TERWILLIGER TC; BOLLAG GE; STERNBERG DW; KOSHLAND DE
S-METHYL GLUTATHIONE SYNTHESIS IS CATALYZED BY THE CHER METHYLTRANSFERASE IN ESCHERICHIA-COLI
0 1
164 8 29 658 1995 BIOCHEMISTRY 34 (1): 378-384
LEE ME; DYER DH; KLEIN OD; BOLDUC JM; STODDARD BL; et al.
MUTATIONAL ANALYSIS OF THE CATALYTIC RESIDUES LYSINE-230 AND TYROSINE-160 IN THE NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE FROM ESCHERICHIA-COLI
4 32
165 9 29 683 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (44): 27927-27930
Biemann HP; Harmer SL; Koshland DE
An aspartate insulin receptor chimera mitogenically activates fibroblasts
0 9
166 9 28 156 1973 SEIKAGAKU 45 (11): 941-950
KOSHLAND DE
INDUCED CONFORMATIONAL-CHANGES IN ENZYME CONTROL
0 0
167 4 28 160 1974 FEBS LETTERS 43: S3-S9
KOSHLAND DE
CHEMOTAXIS AS A MODEL FOR SENSORY SYSTEMS
0 0
168 9 28 243 1980 TRENDS IN BIOCHEMICAL SCIENCES 5 (11): 297-302
KOSHLAND DE
BIOCHEMISTRY OF SENSING AND ADAPTATION
4 18
169 7 28 349 1987 BIOCHEMICAL SOCIETY SYMPOSIUM (54): 183-195
WALSH K; SCHENA M; FLINT AJ; KOSHLAND DE
COMPENSATORY REGULATION IN METABOLIC PATHWAYS - RESPONSES TO INCREASES AND DECREASES IN CITRATE SYNTHASE LEVELS
0 0
170 1 28 363 1987 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 84 (13): 4660-4664
MOCHLYROSEN D; BASBAUM AI; KOSHLAND DE
DISTINCT CELLULAR AND REGIONAL LOCALIZATION OF IMMUNOREACTIVE PROTEIN-KINASE-C IN RAT-BRAIN
1 99
# LCR NCR Node / Date / Journal / Author LCS GCS
171 0 28 468 1990 NEURON 4 (4): 615-621
MCFADDEN PN; KOSHLAND DE
PARALLEL PATHWAYS FOR HABITUATION IN REPETITIVELY STIMULATED PC12 CELLS
8 13
172 4 28 547 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89 (21): 10257-10261
MARTIN PT; KOSHLAND DE
REGULATION OF NEUROSECRETORY HABITUATION IN PC12-CELLS - PARALLEL PATHWAYS USED BY CAMP AND CALCIUM
2 12
173 2 27 27 1958 JOURNAL OF BIOLOGICAL CHEMISTRY 233 (4): 986-990
PARK JH; KOSHLAND DE
HYDROLYTIC ACTIVITY OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
1 85
174 3 27 30 1958 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 44 (2): 98-104
KOSHLAND DE
APPLICATION OF A THEORY OF ENZYME SPECIFICITY TO PROTEIN SYNTHESIS
16 629
175 3 27 34 1959 JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY 54: 245-258
KOSHLAND DE
ENZYME FLEXIBILITY AND ENZYME ACTION
10 76
176 1 27 131 1971 JOURNAL OF BIOLOGICAL CHEMISTRY 246 (10): 3092-&
CORNISHB.AJ; KOSHLAND DE
QUATERNARY STRUCTURE OF PROTEINS COMPOSED OF IDENTICAL SUBUNITS
0 36
177 4 27 166 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249 (13): 4110-4118
BELL RM; PARSONS SM; DUBRAVAC SA; REDFIELD AG; KOSHLAND DE
CHARACTERIZATION OF SLOWLY INTERCONVERTIBLE STATES OF PHOSPHORIBOSYLADENOSINE TRIPHOSPHATE SYNTHETASE DEPENDENT ON TEMPERATURE, SUBSTRATES, AND HISTIDINE
2 35
178 2 27 213 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253 (11): 3821-3829
INGOLIA TD; KOSHLAND DE
ROLE OF CALCIUM IN FUSION OF ARTIFICIAL VESICLES
0 48
179 4 27 231 1979 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 76 (8): 3693-3697
PAONI NF; KOSHLAND DE
PERMEABILIZATION OF CELLS FOR STUDIES ON THE BIOCHEMISTRY OF BACTERIAL CHEMOTAXIS
10 27
180 1 27 507 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266 (12): 7388-7392
MARTIN PT; KOSHLAND DE
THE BIOCHEMISTRY OF THE NEURON - NEUROSECRETORY HABITUATION TO REPETITIVE DEPOLARIZATIONS IN PC12 CELLS
3 8
# LCR NCR Node / Date / Journal / Author LCS GCS
181 1 27 544 1992 JOURNAL OF BACTERIOLOGY 174 (15): 5117-5122
SANDERS DA; GILLECECASTRO BL; BURLINGAME AL; KOSHLAND DE
PHOSPHORYLATION SITE OF NTRC, A PROTEIN PHOSPHATASE WHOSE COVALENT INTERMEDIATE ACTIVATES TRANSCRIPTION
1 73
182 7 27 705 1999 PROTEIN ENGINEERING 12 (10): 863-871
Jeffery CJ; Koshland DE
The Escherichia coli aspartate receptor: sequence specificity of a transmembrane helix studied by hydrophobic-biased random mutagenesis
0 2
183 2 26 19 1956 JOURNAL OF BIOLOGICAL CHEMISTRY 219 (2): 719-725
KOWALSKY A; WYTTENBACH C; LANGER L; KOSHLAND DE
TRANSFER OF OXYGEN IN THE GLUTAMINE SYNTHETASE REACTION
1 55
184 5 26 108 1969 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 62 (4): 1121-&
LEVITZKI A; KOSHLAND DE
NEGATIVE COOPERATIVITY IN REGULATORY ENZYMES
8 414
185 0 26 121 1970 JOURNAL OF MOLECULAR BIOLOGY 50 (3): 617-&
HABER JE; KOSHLAND DE
AN EVALUATION OF RELATEDNESS OF PROTEINS BASED ON COMPARISON OF AMINO ACID SEQUENCES
0 65
186 1 26 126 1971 BIOCHEMISTRY 10 (5): 798-&
TEIPEL JW; KOSHLAND DE
KINETIC ASPECTS OF CONFORMATIONAL CHANGES IN PROTEINS .2. STRUCTURAL CHANGES IN RENATURATION OF DENATURED PROTEINS
1 104
187 2 26 165 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249 (13): 4104-4109
PARSONS SM; KOSHLAND DE
RAPID ISOLATION OF PHOSPHORIBOSYLADENOSINE TRIPHOSPHATE SYNTHETASE AND COMPARISON TO NATIVE ENZYME
2 37
188 2 26 167 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249 (13): 4119-4126
PARSONS SM; KOSHLAND DE
MULTIPLE AGGREGATION STATES OF PHOSPHORIBOSYLADENOSINE TRIPHOSPHATE SYNTHETASE
2 25
189 3 26 168 1974 JOURNAL OF MOLECULAR BIOLOGY 84 (3): 399-406
MACNAB R; KOSHLAND DE
BACTERIAL MOTILITY AND CHEMOTAXIS - LIGHT-INDUCED TUMBLING RESPONSE AND VISUALIZATION OF INDIVIDUAL FLAGELLA
0 106
190 4 26 199 1977 JOURNAL OF BACTERIOLOGY 130 (1): 223-231
WARRICK HM; TAYLOR BL; KOSHLAND DE
CHEMOTACTIC MECHANISM OF SALMONELLA-TYPHIMURIUM - PRELIMINARY MAPPING AND CHARACTERIZATION OF MUTANTS
18 56
# LCR NCR Node / Date / Journal / Author LCS GCS
191 7 26 218 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75 (9): 4150-4154
KHAN S; MACNAB RM; DEFRANCO AL; KOSHLAND DE
INVERSION OF A BEHAVIORAL RESPONSE IN BACTERIAL CHEMOTAXIS - EXPLANATION AT MOLECULAR LEVEL
10 69
192 5 26 228 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254 (19): 9695-9702
CLARKE S; KOSHLAND DE
MEMBRANE-RECEPTORS FOR ASPARTATE AND SERINE IN BACTERIAL CHEMOTAXIS
38 156
193 2 26 252 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78 (11): 6840-6844
GOLDBETER A; KOSHLAND DE
AN AMPLIFIED SENSITIVITY ARISING FROM COVALENT MODIFICATION IN BIOLOGICAL-SYSTEMS
14 216
194 9 26 257 1982 JOURNAL OF MOLECULAR BIOLOGY 161 (3): 395-416
GOLDBETER A; KOSHLAND DE
SIMPLE MOLECULAR-MODEL FOR SENSING AND ADAPTATION BASED ON RECEPTOR MODIFICATION WITH APPLICATION TO BACTERIAL CHEMOTAXIS
1 21
195 7 26 269 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258 (16): 9608-9611
TERWILLIGER TC; BOGONEZ E; WANG EA; KOSHLAND DE
SITES OF METHYL ESTERIFICATION ON THE ASPARTATE RECEPTOR INVOLVED IN BACTERIAL CHEMOTAXIS
16 44
196 5 26 284 1984 TRENDS IN BIOCHEMICAL SCIENCES 9 (4): 155-159
KOSHLAND DE
CONTROL OF ENZYME-ACTIVITY AND METABOLIC PATHWAYS
2 19
197 4 26 328 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83 (21): 8137-8141
ELLIS L; MORGAN DO; KOSHLAND DE; CLAUSER E; MOE GR; et al.
LINKING FUNCTIONAL DOMAINS OF THE HUMAN INSULIN-RECEPTOR WITH THE BACTERIAL ASPARTATE RECEPTOR
2 30
198 1 26 357 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262 (8): 3432-3435
KRAUSS SW; MOCHLYROSEN D; KOSHLAND DE; LINN S
EXPOSURE OF HELA DNA POLYMERASE-ALPHA TO PROTEIN-KINASE-C AFFECTS ITS CATALYTIC PROPERTIES
1 55
199 2 26 362 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262 (22): 10422-10425
THORSNESS PE; KOSHLAND DE
INACTIVATION OF ISOCITRATE DEHYDROGENASE BY PHOSPHORYLATION IS MEDIATED BY THE NEGATIVE CHARGE OF THE PHOSPHATE
13 184
200 1 26 721 2001 SCIENCE 294 (5541): 380-382
Mahal LK; Charter NW; Angata K; Fukuda M; Koshland DE; et al.
A small-molecule modulator of poly-alpha 2,8-sialic acid expression on cultured neurons and tumor cells
1 23

#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
101	5	37	432 1989 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 86 (15): 5683-5687 MOE GR; BOLLAG GE; KOSHLAND DE TRANSMEMBRANE SIGNALING BY A CHIMERA OF THE ESCHERICHIA-COLI ASPARTATE RECEPTOR AND THE HUMAN INSULIN-RECEPTOR	10	50
102	4	36	117 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245 (1): 80-& LONG CW; LEVITZKI A; KOSHLAND DE SUBUNIT STRUCTURE AND SUBUNIT INTERACTIONS OF CYTIDINE TRIPHOSPHATE SYNTHETASE	7	72
103	5	36	217 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75 (8): 3659-3663 STOCK JB; KOSHLAND DE PROTEIN METHYLESTERASE INVOLVED IN BACTERIAL SENSING	40	230
104	8	36	242 1980 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 77 (12): 7157-7161 WANG EA; KOSHLAND DE RECEPTOR STRUCTURE IN THE BACTERIAL SENSING SYSTEM	33	124
105	16	36	273 1983 TRENDS IN NEUROSCIENCES 6 (4): 133-137 KOSHLAND DE THE BACTERIUM AS A MODEL NEURON	1	12
106	3	36	278 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259 (15): 9646-9654 WALSH K; KOSHLAND DE DETERMINATION OF FLUX THROUGH THE BRANCH POINT OF 2 METABOLIC CYCLES - THE TRICARBOXYLIC-ACID CYCLE AND THE GLYOXYLATE SHUNT	8	101
107	2	35	49 1962 JOURNAL OF BIOLOGICAL CHEMISTRY 237 (8): 2493-& RAY WJ; KOSHLAND DE IDENTIFICATION OF AMINO ACIDS INVOLVED IN PHOSPHOGLUCOMUTASE ACTION	9	241
108	5	35	219 1979 BIOCHEMISTRY 18 (25): 5599-5605 ZUKIN RS; HARTIG PR; KOSHLAND DE EFFECT OF AN INDUCED CONFORMATIONAL CHANGE ON THE PHYSICAL-PROPERTIES OF 2 CHEMOTACTIC RECEPTOR MOLECULES	2	22
109	0	35	397 1988 NATURE 331 (6156): 499-504 KOSHLAND DE; MITCHISON TJ; KIRSCHNER MW POLEWARDS CHROMOSOME MOVEMENT DRIVEN BY MICROTUBULE DEPOLYMERIZATION INVITRO	0	225
110	5	35	575 1993 BIOCHEMISTRY 32 (36): 9302-9309 DEAN AM; KOSHLAND DE KINETIC MECHANISM OF ESCHERICHIA-COLI ISOCITRATE DEHYDROGENASE	9	34
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
111	8	35	689 1996 PROTEIN SCIENCE 5 (2): 348-356 Zhang T; Koshland DE Computational method for relative binding energies of enzyme-substrate complexes	0	28
112	11	35	713 2000 JOURNAL OF MOLECULAR BIOLOGY 295 (3): 377-385 Cherbavaz DB; Lee ME; Stroud RM; Koshland DE Active site water molecules revealed in the 2.1 angstrom resolution structure of a site-directed mutant of isocitrate dehydrogenase	0	11
113	2	35	735 2004 BIOCHEMISTRY 43 (43): 13648-13656 Radisky ES; Kwan G; Lu CJK; Koshland DE Binding, proteolytic, and crystallographic analyses of mutations at the protease-inhibitor interface of the subtilisin BPN '/chymotrypsin inhibitor 2 complex	1	3
114	1	34	6 1952 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 74 (9): 2286-2292 KOSHLAND DE EFFECT OF CATALYSTS ON THE HYDROLYSIS OF ACETYL PHOSPHATE - NUCLEOPHILIC DISPLACEMENT MECHANISMS IN ENZYMATIC REACTIONS	5	170
115	3	34	15 1955 DISCUSSIONS OF THE FARADAY SOCIETY (20): 142-148 KOSHLAND DE ISOTOPIC EXCHANGE CRITERIA FOR ENZYME MECHANISMS	0	7
116	4	34	191 1976 SCIENCE 193 (4251): 405-408 ZUKIN RS; KOSHLAND DE MG2+,CA2+-DEPENDENT ADENOSINE-TRIPHOSPHATASE AS RECEPTOR FOR DIVALENT-CATIONS IN BACTERIAL SENSING	4	22
117	1	34	294 1985 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82 (11): 3577-3581 WALSH K; KOSHLAND DE CHARACTERIZATION OF RATE-CONTROLLING STEPS INVIVO BY USE OF AN ADJUSTABLE EXPRESSION VECTOR	1	89
118	15	34	322 1986 JOURNAL OF BACTERIOLOGY 165 (1): 276-282 RUSSO AF; KOSHLAND DE IDENTIFICATION OF THE TIP-ENCODED RECEPTOR IN BACTERIAL SENSING	0	10
119	3	34	469 1990 NEURON 5 (6): 875-880 MORIMOTO BH; KOSHLAND DE INDUCTION AND EXPRESSION OF LONG-TERM AND SHORT-TERM NEUROSECRETORY POTENTIATION IN A NEURAL CELL-LINE	7	52
120	8	34	583 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268 (27): 19991-19997 MILLIGAN DL; KOSHLAND DE PURIFICATION AND CHARACTERIZATION OF THE PERIPLASMIC DOMAIN OF THE ASPARTATE CHEMORECEPTOR	7	18
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
121	2	33	122 1970 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 66 (2): 445-& STORM DR; KOSHLAND DE A SOURCE FOR SPECIAL CATALYTIC POWER OF ENZYMES - ORBITAL STEERIN	8	163
122	2	33	196 1977 BIOCHEMISTRY 16 (3): 381-386 ZUKIN RS; STRANGE PG; HEAVEY LR; KOSHLAND DE PROPERTIES OF GALACTOSE BINDING-PROTEIN OF SALMONELLA-TYPHIMURIUM AND ESCHERICHIA-COLI	7	47
123	7	33	216 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75 (6): 2820-2824 RUBIK BA; KOSHLAND DE POTENTIATION, DESENSITIZATION, AND INVERSION OF RESPONSE IN BACTERIAL SENSING OF CHEMICAL STIMULI	15	52
124	10	33	227 1979 JOURNAL OF BACTERIOLOGY 140 (3): 798-804 INGOLIA TD; KOSHLAND DE RESPONSE TO A METAL-ION CITRATE COMPLEX IN BACTERIAL SENSING	1	12
125	3	33	259 1982 QUARTERLY REVIEWS OF BIOPHYSICS 15 (3): 555-591 GOLDBETER A; KOSHLAND DE SENSITIVITY AMPLIFICATION IN BIOCHEMICAL SYSTEMS	3	84
126	2	33	428 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264 (22): 12765-12771 MCFADDEN PN; MANDPE A; KOSHLAND DE CALCIUM-INDEPENDENT AND LIPID-INDEPENDENT PROTEIN KINASE-C AUTOPHOSPHORYLATION - ACTIVATION BY LOW PH	0	26
127	2	33	487 1990 SCIENCE 249 (4967): 408-411 FLINT AJ; PALADINI RD; KOSHLAND DE AUTOPHOSPHORYLATION OF PROTEIN KINASE-C AT 3-SEPARATED REGIONS OF ITS PRIMARY SEQUENCE	1	120
128	3	33	737 2005 BIOCHEMISTRY 44 (18): 6823-6830 Radisky ES; Lu CJK; Kwan G; Koshland DE Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2	0	0
129	5	32	118 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245 (2): 276-& KIRTLEY ME; KOSHLAND DE PROPERTIES OF RABBIT MUSCLE GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE LABELED WITH A REPORTER-GROUP	1	22
130	4	32	128 1971 BIOCHEMISTRY 10 (18): 3371-& LEVITZKI A; STALLCUP WB; KOSHLAND DE HALF-OF-SITES REACTIVITY AND CONFORMATIONAL STATES OF CYTIDINE TRIPHOSPHATE SYNTHETASE	12	205
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
131	10	32	184 1976 FEBS LETTERS 62: E47-E52 KOSHLAND DE ROLE OF FLEXIBILITY IN SPECIFICITY, CONTROL AND EVOLUTION OF ENZYMES	0	28
132	10	32	277 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259 (12): 7719-7725 TERWILLIGER TC; KOSHLAND DE SITES OF METHYL ESTERIFICATION AND DEAMINATION ON THE ASPARTATE RECEPTOR INVOLVED IN CHEMOTAXIS	19	78
133	6	32	576 1993 BIOCHEMISTRY 32 (36): 9310-9316 STODDARD BL; DEAN A; KOSHLAND DE STRUCTURE OF ISOCITRATE DEHYDROGENASE WITH ISOCITRATE, NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE, AND CALCIUM AT 2.5-ANGSTROM RESOLUTION - A PSEUDO-MICHAELIS TERNARY COMPLEX	10	67
134	9	32	585 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90 (4): 1146-1153 STODDARD BL; KOSHLAND DE MOLECULAR RECOGNITION ANALYZED BY DOCKING SIMULATIONS - THE ASPARTATE RECEPTOR AND ISOCITRATE DEHYDROGENASE FROM ESCHERICHIA-COLI	0	26
135	3	32	625 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269 (6): 4065-4069 MORIMOTO BH; KOSHLAND DE CONDITIONAL ACTIVATION OF CAMP SIGNAL-TRANSDUCTION BY PROTEIN-KINASE-C - THE EFFECT OF PHORBOL ESTERS ON ADENYLYL-CYCLASE IN PERMEABILIZED AND INTACT-CELLS	0	31
136	9	32	626 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269 (15): 11054-11059 SHAPIRO MJ; KOSHLAND DE MUTAGENIC STUDIES OF THE INTERACTION BETWEEN THE ASPARTATE RECEPTOR AND METHYLTRANSFERASE FROM ESCHERICHIA-COLI	9	27
137	15	32	657 1995 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 33 (23-24): 2375-2378 KOSHLAND DE THE KEY-LOCK THEORY AND THE INDUCED FIT THEORY	0	110
138	4	31	11 1954 JOURNAL OF BIOLOGICAL CHEMISTRY 208 (1): 139-148 KOSHLAND DE; STEIN SS CORRELATION OF BOND BREAKING WITH ENZYME SPECIFICITY - CLEAVAGE POINT OF INVERTASE	3	45
139	3	31	21 1956 JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY 47: 217-234 KOSHLAND DE MOLECULAR GEOMETRY IN ENZYME ACTION	6	34
140	3	31	83 1966 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 56 (5): 1606-& NEET KE; KOSHLAND DE CONVERSION OF SERINE AT ACTIVE SITE OF SUBTILISIN TO CYSTEINE - A CHEMICAL MUTATION	2	147
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
141	4	31	190 1976 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73 (3): 762-766 STRANGE PG; KOSHLAND DE RECEPTOR INTERACTIONS IN A SIGNALING SYSTEM - COMPETITION BETWEEN RIBOSE RECEPTOR AND GALACTOSE RECEPTOR IN CHEMOTAXIS RESPONSE	18	93
142	3	31	205 1977 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 74 (5): 1932-1936 ZUKIN RS; HARTIG PR; KOSHLAND DE USE OF A DISTANT REPORTER GROUP AS EVIDENCE FOR A CONFORMATIONAL CHANGE IN A SENSORY RECEPTOR	4	66
143	6	31	240 1980 JOURNAL OF SUPRAMOLECULAR STRUCTURE 13 (3): 315-328 CLARKE S; SPARROW K; PANASENKO S; KOSHLAND DE INVITRO METHYLATION OF BACTERIAL CHEMOTAXIS PROTEINS - CHARACTERIZATION OF PROTEIN METHYLTRANSFERASE ACTIVITY IN CRUDE EXTRACTS OF SALMONELLA-TYPHIMURIUM	5	32
144	11	31	246 1981 CELL 27 (1): 37-44 STOCK JB; MADERIS AM; KOSHLAND DE BACTERIAL CHEMOTAXIS IN THE ABSENCE OF RECEPTOR CARBOXYLMETHYLATION	9	40
145	8	31	293 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260 (21): 1711-1718 MOWBRAY SL; FOSTER DL; KOSHLAND DE PROTEOLYTIC FRAGMENTS IDENTIFIED WITH DOMAINS OF THE ASPARTATE CHEMORECEPTOR	19	60
146	14	31	393 1988 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 53: 11-17 KOSHLAND DE; SANDERS DA; WEIS RM ROLES OF METHYLATION AND PHOSPHORYLATION IN THE BACTERIAL SENSING SYSTEM	0	6
147	8	31	679 1996 BIOCHEMISTRY 35 (9): 2854-2864 Brubaker MJ; Dyer DH; Stoddard B; Koshland DE Synthesis, kinetics, and structural studies of a photolabile caged isocitrate: A catalytic trigger for isocitrate dehydrogenase	1	11
148	8	31	695 1997 BIOCHEMISTRY 36 (45): 13890-13896 FinerMoore J; Tsutakawa SE; Cherbavaz DB; LaPorte DC; Koshland DE; et al. Access to phosphorylation in isocitrate dehydrogenase may occur by domain shifting	2	17
149	11	31	717 2001 BIOCHEMISTRY 40 (14): 4234-4241 Doyle SA; Beernink PT; Koshland DE Structural basis for a change in substrate specificity: Crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP	0	8
150	3	30	91 1967 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 57 (6): 1670-& FENSELAU A; KOENIG D; KOSHLAND DE; LATHAM HG; WEINER H A SYSTEMATIC METHOD FOR INTRODUCING HEAVY ATOMS INTO A PROTEIN MOLECULE	0	6
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
151	2	30	248 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256 (9): 4640-4648 WANG JYJ; KOSHLAND DE THE IDENTIFICATION OF DISTINCT PROTEIN-KINASES AND PHOSPHATASES IN THE PROKARYOTE SALMONELLA-TYPHIMURIUM	6	62
152	0	30	356 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262 (5): 2291-2297 MOCHLYROSEN D; KOSHLAND DE DOMAIN-STRUCTURE AND PHOSPHORYLATION OF PROTEIN-KINASE-C	10	161
153	8	30	577 1993 BIOCHEMISTRY 32 (36): 9317-9322 STODDARD BL; KOSHLAND DE STRUCTURE OF ISOCITRATE DEHYDROGENASE WITH ALPHA-KETOGLUTARATE AT 2.7-ANGSTROM RESOLUTION - CONFORMATIONAL-CHANGES INDUCED BY DECARBOXYLATION OF ISOCITRATE	9	38
154	6	30	621 1994 BIOCHEMISTRY 33 (12): 3457-3463 JEFFERY CJ; KOSHLAND DE A SINGLE HYDROPHOBIC TO HYDROPHOBIC SUBSTITUTION IN THE TRANSMEMBRANE DOMAIN IMPAIRS ASPARTATE RECEPTOR FUNCTION	4	11
155	13	30	660 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270 (41): 24038-24042 CHEN XM; KOSHLAND DE THE N-TERMINAL CYTOPLASMIC TAIL OF THE ASPARTATE RECEPTOR IS NOT ESSENTIAL IN SIGNAL-TRANSDUCTION OF BACTERIAL CHEMOTAXIS	1	11
156	3	29	51 1963 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 103 (2): 630-& KOSHLAND DE .1. ASPECTS OF 2-COMPONENT IMMUNOLOGY - PROPERTIES OF ACTIVE SITE OF ENZYMES	0	15
157	1	29	159 1974 BIOCHEMISTRY 13 (22): 4473-4478 AKSAMIT RR; KOSHLAND DE IDENTIFICATION OF RIBOSE BINDING-PROTEIN AS RECEPTOR FOR RIBOSE CHEMOTAXIS IN SALMONELLA-TYPHIMURIUM	19	83
158	11	29	186 1976 FEDERATION PROCEEDINGS 35 (10): 2104-2111 KOSHLAND DE EVOLUTION OF FUNCTION IN ENZYMES	3	27
159	3	29	189 1976 NATURE 262 (5568): 467-471 SPUDICH JL; KOSHLAND DE NON-GENETIC INDIVIDUALITY - CHANCE IN SINGLE CELL	7	109
160	5	29	192 1976 TRENDS IN BIOCHEMICAL SCIENCES 1 (1): 1-3 KOSHLAND DE BACTERIAL CHEMOTAXIS AS A SIMPLE MODEL FOR A SENSORY SYSTEM	1	3
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
161	10	29	281 1984 METHODS IN ENZYMOLOGY 106: 310-321 BINSTOCK J; CLARKE S; KOSHLAND DE THE PROTEIN CARBOXYLMETHYLTRANSFERASE INVOLVED IN ESCHERICHIA-COLI AND SALMONELLA-TYPHIMURIUM CHEMOTAXIS	0	0
162	9	29	292 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260 (21): 1706-1710 FOSTER DL; MOWBRAY SL; JAP BK; KOSHLAND DE PURIFICATION AND CHARACTERIZATION OF THE ASPARTATE CHEMORECEPTOR	21	57
163	7	29	323 1986 JOURNAL OF BACTERIOLOGY 165 (3): 958-963 TERWILLIGER TC; BOLLAG GE; STERNBERG DW; KOSHLAND DE S-METHYL GLUTATHIONE SYNTHESIS IS CATALYZED BY THE CHER METHYLTRANSFERASE IN ESCHERICHIA-COLI	0	1
164	8	29	658 1995 BIOCHEMISTRY 34 (1): 378-384 LEE ME; DYER DH; KLEIN OD; BOLDUC JM; STODDARD BL; et al. MUTATIONAL ANALYSIS OF THE CATALYTIC RESIDUES LYSINE-230 AND TYROSINE-160 IN THE NADP(+)-DEPENDENT ISOCITRATE DEHYDROGENASE FROM ESCHERICHIA-COLI	4	32
165	9	29	683 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (44): 27927-27930 Biemann HP; Harmer SL; Koshland DE An aspartate insulin receptor chimera mitogenically activates fibroblasts	0	9
166	9	28	156 1973 SEIKAGAKU 45 (11): 941-950 KOSHLAND DE INDUCED CONFORMATIONAL-CHANGES IN ENZYME CONTROL	0	0
167	4	28	160 1974 FEBS LETTERS 43: S3-S9 KOSHLAND DE CHEMOTAXIS AS A MODEL FOR SENSORY SYSTEMS	0	0
168	9	28	243 1980 TRENDS IN BIOCHEMICAL SCIENCES 5 (11): 297-302 KOSHLAND DE BIOCHEMISTRY OF SENSING AND ADAPTATION	4	18
169	7	28	349 1987 BIOCHEMICAL SOCIETY SYMPOSIUM (54): 183-195 WALSH K; SCHENA M; FLINT AJ; KOSHLAND DE COMPENSATORY REGULATION IN METABOLIC PATHWAYS - RESPONSES TO INCREASES AND DECREASES IN CITRATE SYNTHASE LEVELS	0	0
170	1	28	363 1987 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 84 (13): 4660-4664 MOCHLYROSEN D; BASBAUM AI; KOSHLAND DE DISTINCT CELLULAR AND REGIONAL LOCALIZATION OF IMMUNOREACTIVE PROTEIN-KINASE-C IN RAT-BRAIN	1	99
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
171	0	28	468 1990 NEURON 4 (4): 615-621 MCFADDEN PN; KOSHLAND DE PARALLEL PATHWAYS FOR HABITUATION IN REPETITIVELY STIMULATED PC12 CELLS	8	13
172	4	28	547 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89 (21): 10257-10261 MARTIN PT; KOSHLAND DE REGULATION OF NEUROSECRETORY HABITUATION IN PC12-CELLS - PARALLEL PATHWAYS USED BY CAMP AND CALCIUM	2	12
173	2	27	27 1958 JOURNAL OF BIOLOGICAL CHEMISTRY 233 (4): 986-990 PARK JH; KOSHLAND DE HYDROLYTIC ACTIVITY OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE	1	85
174	3	27	30 1958 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 44 (2): 98-104 KOSHLAND DE APPLICATION OF A THEORY OF ENZYME SPECIFICITY TO PROTEIN SYNTHESIS	16	629
175	3	27	34 1959 JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY 54: 245-258 KOSHLAND DE ENZYME FLEXIBILITY AND ENZYME ACTION	10	76
176	1	27	131 1971 JOURNAL OF BIOLOGICAL CHEMISTRY 246 (10): 3092-& CORNISHB.AJ; KOSHLAND DE QUATERNARY STRUCTURE OF PROTEINS COMPOSED OF IDENTICAL SUBUNITS	0	36
177	4	27	166 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249 (13): 4110-4118 BELL RM; PARSONS SM; DUBRAVAC SA; REDFIELD AG; KOSHLAND DE CHARACTERIZATION OF SLOWLY INTERCONVERTIBLE STATES OF PHOSPHORIBOSYLADENOSINE TRIPHOSPHATE SYNTHETASE DEPENDENT ON TEMPERATURE, SUBSTRATES, AND HISTIDINE	2	35
178	2	27	213 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253 (11): 3821-3829 INGOLIA TD; KOSHLAND DE ROLE OF CALCIUM IN FUSION OF ARTIFICIAL VESICLES	0	48
179	4	27	231 1979 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 76 (8): 3693-3697 PAONI NF; KOSHLAND DE PERMEABILIZATION OF CELLS FOR STUDIES ON THE BIOCHEMISTRY OF BACTERIAL CHEMOTAXIS	10	27
180	1	27	507 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266 (12): 7388-7392 MARTIN PT; KOSHLAND DE THE BIOCHEMISTRY OF THE NEURON - NEUROSECRETORY HABITUATION TO REPETITIVE DEPOLARIZATIONS IN PC12 CELLS	3	8
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
181	1	27	544 1992 JOURNAL OF BACTERIOLOGY 174 (15): 5117-5122 SANDERS DA; GILLECECASTRO BL; BURLINGAME AL; KOSHLAND DE PHOSPHORYLATION SITE OF NTRC, A PROTEIN PHOSPHATASE WHOSE COVALENT INTERMEDIATE ACTIVATES TRANSCRIPTION	1	73
182	7	27	705 1999 PROTEIN ENGINEERING 12 (10): 863-871 Jeffery CJ; Koshland DE The Escherichia coli aspartate receptor: sequence specificity of a transmembrane helix studied by hydrophobic-biased random mutagenesis	0	2
183	2	26	19 1956 JOURNAL OF BIOLOGICAL CHEMISTRY 219 (2): 719-725 KOWALSKY A; WYTTENBACH C; LANGER L; KOSHLAND DE TRANSFER OF OXYGEN IN THE GLUTAMINE SYNTHETASE REACTION	1	55
184	5	26	108 1969 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 62 (4): 1121-& LEVITZKI A; KOSHLAND DE NEGATIVE COOPERATIVITY IN REGULATORY ENZYMES	8	414
185	0	26	121 1970 JOURNAL OF MOLECULAR BIOLOGY 50 (3): 617-& HABER JE; KOSHLAND DE AN EVALUATION OF RELATEDNESS OF PROTEINS BASED ON COMPARISON OF AMINO ACID SEQUENCES	0	65
186	1	26	126 1971 BIOCHEMISTRY 10 (5): 798-& TEIPEL JW; KOSHLAND DE KINETIC ASPECTS OF CONFORMATIONAL CHANGES IN PROTEINS .2. STRUCTURAL CHANGES IN RENATURATION OF DENATURED PROTEINS	1	104
187	2	26	165 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249 (13): 4104-4109 PARSONS SM; KOSHLAND DE RAPID ISOLATION OF PHOSPHORIBOSYLADENOSINE TRIPHOSPHATE SYNTHETASE AND COMPARISON TO NATIVE ENZYME	2	37
188	2	26	167 1974 JOURNAL OF BIOLOGICAL CHEMISTRY 249 (13): 4119-4126 PARSONS SM; KOSHLAND DE MULTIPLE AGGREGATION STATES OF PHOSPHORIBOSYLADENOSINE TRIPHOSPHATE SYNTHETASE	2	25
189	3	26	168 1974 JOURNAL OF MOLECULAR BIOLOGY 84 (3): 399-406 MACNAB R; KOSHLAND DE BACTERIAL MOTILITY AND CHEMOTAXIS - LIGHT-INDUCED TUMBLING RESPONSE AND VISUALIZATION OF INDIVIDUAL FLAGELLA	0	106
190	4	26	199 1977 JOURNAL OF BACTERIOLOGY 130 (1): 223-231 WARRICK HM; TAYLOR BL; KOSHLAND DE CHEMOTACTIC MECHANISM OF SALMONELLA-TYPHIMURIUM - PRELIMINARY MAPPING AND CHARACTERIZATION OF MUTANTS	18	56
#	LCR	NCR	Node / Date / Journal / Author	LCS	GCS
191	7	26	218 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75 (9): 4150-4154 KHAN S; MACNAB RM; DEFRANCO AL; KOSHLAND DE INVERSION OF A BEHAVIORAL RESPONSE IN BACTERIAL CHEMOTAXIS - EXPLANATION AT MOLECULAR LEVEL	10	69
192	5	26	228 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254 (19): 9695-9702 CLARKE S; KOSHLAND DE MEMBRANE-RECEPTORS FOR ASPARTATE AND SERINE IN BACTERIAL CHEMOTAXIS	38	156
193	2	26	252 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78 (11): 6840-6844 GOLDBETER A; KOSHLAND DE AN AMPLIFIED SENSITIVITY ARISING FROM COVALENT MODIFICATION IN BIOLOGICAL-SYSTEMS	14	216
194	9	26	257 1982 JOURNAL OF MOLECULAR BIOLOGY 161 (3): 395-416 GOLDBETER A; KOSHLAND DE SIMPLE MOLECULAR-MODEL FOR SENSING AND ADAPTATION BASED ON RECEPTOR MODIFICATION WITH APPLICATION TO BACTERIAL CHEMOTAXIS	1	21
195	7	26	269 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258 (16): 9608-9611 TERWILLIGER TC; BOGONEZ E; WANG EA; KOSHLAND DE SITES OF METHYL ESTERIFICATION ON THE ASPARTATE RECEPTOR INVOLVED IN BACTERIAL CHEMOTAXIS	16	44
196	5	26	284 1984 TRENDS IN BIOCHEMICAL SCIENCES 9 (4): 155-159 KOSHLAND DE CONTROL OF ENZYME-ACTIVITY AND METABOLIC PATHWAYS	2	19
197	4	26	328 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83 (21): 8137-8141 ELLIS L; MORGAN DO; KOSHLAND DE; CLAUSER E; MOE GR; et al. LINKING FUNCTIONAL DOMAINS OF THE HUMAN INSULIN-RECEPTOR WITH THE BACTERIAL ASPARTATE RECEPTOR	2	30
198	1	26	357 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262 (8): 3432-3435 KRAUSS SW; MOCHLYROSEN D; KOSHLAND DE; LINN S EXPOSURE OF HELA DNA POLYMERASE-ALPHA TO PROTEIN-KINASE-C AFFECTS ITS CATALYTIC PROPERTIES	1	55
199	2	26	362 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262 (22): 10422-10425 THORSNESS PE; KOSHLAND DE INACTIVATION OF ISOCITRATE DEHYDROGENASE BY PHOSPHORYLATION IS MEDIATED BY THE NEGATIVE CHARGE OF THE PHOSPHATE	13	184
200	1	26	721 2001 SCIENCE 294 (5541): 380-382 Mahal LK; Charter NW; Angata K; Fukuda M; Koshland DE; et al. A small-molecule modulator of poly-alpha 2,8-sialic acid expression on cultured neurons and tumor cells	1	23

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