#	Cited nodes	Nodes / Authors	GCS	LCS
601	18	686 2002 JOURNAL OF CELL SCIENCE 115(23):4587-4595 Posthaus H; Williamson L; Baumann D; Kemler R; Caldelari R; Suter MM; Schwarz H; Muller E beta-catenin is not required for proliferation and differentiation of epidermal mouse keratinocytes	3	0
602	5	706 2002 JOURNAL OF SURGICAL ONCOLOGY 80(4):204-213 Neibergs HL; Hein DW; Spratt JS Genetic profiling of colon cancer	3	0
603	3	707 2002 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 13(5):1152-1161 Price VR; Reed CA; Lieberthal W; Schwartz JH ATP depletion of tubular cells causes dissociation of the zonula adherens and nuclear translocation of beta-catenin and LEF-1	3	1
604	4	719 2002 MOLECULAR CARCINOGENESIS 33(3):131-136 Kugoh H; Kleymenova E; Walker CL Retention of membrane-localized beta-catenin in cells lacking functional polycystin-1 and tuberin	3	0
605	12	735 2002 ONCOGENE 21(38):5906-5911 Sekine S; Shibata T; Sakamoto M; Hirohashi S Target disruption of the mutant beta-catenin gene in colon cancer cell line HCT116: preservation of its malignant phenotype	3	1
606	12	741 2002 ONCOGENE 21(52):7981-7990 Moreno-Bueno G; Hardisson D; Sanchez C; Sarrio D; Cassia R; Garcia-Rostan G; Prat J; Guo MZ; Herman JG; Matias-Guiu X; Esteller M; Palacios J Abnormalities of the APC/beta-catenin pathway in endometrial cancer	3	0
607	21	745 2002 ONCOGENE 21(55):8453-8469 Chesire DR; Isaacs WB Ligand-dependent inhibition of beta-catenin/TCF signaling by androgen receptor	3	2
608	11	815 2003 CLINICAL CANCER RESEARCH 9(4):1291-1300 Verma UN; Surabhi RM; Schmaltieg A; Becerra C; Gaynor RB Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells	3	0
609	4	828 2003 EMBO JOURNAL 22(3):494-501 Dajani R; Fraser E; Roe SM; Yeo M; Good VM; Thompson V; Dale TC; Pearl LH Structural basis for recruitment of glycogen synthase kinase 3 beta to the axin-APC scaffold complex	3	0
610	9	835 2003 GENES & DEVELOPMENT 17(4):488-501 Gunther EJ; Moody SE; Belka GK; Hahn KT; Innocent N; Dugan KD; Cardiff RD; Chodosh LA Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis	3	0
611	13	844 2003 INTERNATIONAL JOURNAL OF CANCER 103(5):652-656 Kielhorn E; Provost E; Olsen D; D'Aquila TG; Smith BL; Camp RL; Rimm DL Tissue microarray-based analysis shows phospho-beta-catenin expression in malignant melanoma is associated with poor outcome	3	1
612	14	851 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(7):5188-5194 Wei Y; Renard CA; Labalette C; Wu YF; Levy L; Neuveut C; Prieur X; Flajolet M; Prigent S; Buendia MA Identification of the LIM protein FHL2 as a coactivator of beta-catenin	3	1
613	5	890 2003 MOLECULAR PSYCHIATRY 8(2):135-144 Lenox RH; Wang L Molecular basis of lithium action: integration of lithium-responsive signaling and gene expression networks	3	1
614	4	25 1999 BULLETIN DU CANCER 86(9):725-726 Durand M; Moles JP beta-catenin mutations in a common skin cancer: pilomatricoma	2	0
615	3	205 2000 COLORECTAL CANCER: NEW ASPECTS OF MOLECULAR BIOLOGY AND IMMUNOLOGY AND THEIR CLINICAL APPLICATIONS 910():1-9 Hanski C; Itzkowitz SH Translating the knowledge of molecular alterations that occur during colon carcinogenesis into clinically relevant solutions	2	0
616	5	208 2000 CURRENT OPINION IN GASTROENTEROLOGY 16(5):419-425 Su GH; Kern SE Molecular genetics of ductal pancreatic neoplasia	2	0
617	3	250 2000 INTERNATIONAL JOURNAL OF CANCER 86(4):480-488 Hanada N; Makino K; Koga H; Morisaki T; Kuwahara H; Masuko N; Tabira Y; Hiraoka T; Kitamura N; Kikuchi A; Saya H NE-dlg, a mammalian homolog of Drosophila DLG tumor suppressor, induces growth suppression and impairment of cell adhesion: Possible involvement of down-regulation of beta-catenin by NE-dlg expression	2	0
618	1	298 2000 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 453(2):129-181 Sankaranarayanan K; Chakraborty R Ionizing radiation and genetic risks XII. The concept of "potential recoverability correction factor" (PRCF) and its use for predicting the risk of radiation-inducible genetic disease in human live births	2	0
619	3	304 2000 NEPHROLOGY DIALYSIS TRANSPLANTATION 15(1):1-2 van Adelsberg J Polycystin-1 interacts with E-cadherin and the catenins - clues to the pathogenesis of cyst formation in ADPKD?	2	0
620	5	319 2000 ONCOLOGY RESEARCH 12(4):193-201 Vincan E; Leet CSF; Reyes NI; Dilley RJ; Thomas RJS; Phillips WA Sodium butyrate-induced differentiation of human LIM2537 colon cancer cells decreases GSK-3 beta activity and increases levels of both membrane-bound and APC/Axin/GSK-3 beta complex-associated pools of beta-catenin	2	0
621	4	320 2000 PATHOLOGY INTERNATIONAL 50(12):945-952 Zhu XD; Kanai Y; Saito A; Kondo Y; Hirohashi S Aberrant expression of beta-catenin and mutation of exon 3 of the beta-catenin gene in renal and urothelial carcinomas	2	0
622	2	353 2001 BULLETIN DU CANCER 88(3):269-276 Claverie JM Bioinformatics of transcriptome analysis in cancer biology	2	0
623	6	380 2001 CANCER RESEARCH 61(19):7101-7109 Shiina H; Igawa M; Urakami S; Shigeno K; Yoneda T; Terashima M; Deguchi M; Ribeiro L; Dahiya R Alterations of beta- and gamma-catenin in N-butyl-N-(-4-hydroxybutyl)nitrosamine-induced murine bladder cancer	2	0
624	7	444 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(4):803-810 Uthoff SMS; Eichenberger MR; Lewis RK; Fox MP; Hamilton CJ; McAuliffe TL; Grimes HL; Galandiuk S Identification of candidate genes in ulcerative colitis and Crohn's disease using cDNA array technology	2	0
625	5	477 2001 JOURNAL OF DERMATOLOGICAL SCIENCE 27(3):170-177 Tsuji H; Ishida-Yamamoto A; Takahashi H; Iizuka H Nuclear localization of beta-catenin in the hair matrix cells and differentiated keratinocytes	2	1
626	5	489 2001 JOURNAL OF SURGICAL RESEARCH 101(1):16-20 Green DW; Roh H; Pippin JA; Drebin JA beta-catenin antisense treatment decreases beta-catenin expression and tumor growth rate in colon carcinoma xenografts	2	0
627	10	491 2001 MECHANISMS OF DEVELOPMENT 109(2):173-181 Ridanpaa M; Fodde R; Kielman M Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures	2	0
628	6	536 2001 ONCOLOGY 61(2):156-161 Saeki H; Tanaka S; Tokunaga E; Kawaguchi H; Ikeda Y; Maehara Y; Sugimachi K Genetic alterations in the human Tcf-4 gene in Japanese patients with sporadic gastrointestinal cancers with microsatellite instability	2	1
629	5	551 2001 SEMINARS IN CANCER BIOLOGY 11(3):219-225 Kucherlapati R; Lin DP; Edelmann W Mouse models for human familial adenomatous polyposis	2	1
630	6	571 2002 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1577(1):81-92 Ballarino M; Marchioni M; Carnevali F The Xenopus laevis beta TrCP gene: genomic organization, alternative splicing, 5 ' and 3 ' region characterization and comparison of its structure with that of human beta TrCP genes	2	0
631	12	574 2002 BIOLOGICAL RESEARCH 35(2):277-286 Hendriks B; Reichmann E Wnt signaling: A complex issue	2	0
632	3	589 2002 CANCER LETTERS 180(2):107-119 Strieder V; Lutz W Regulation of N-myc expression in development and disease	2	0
633	4	599 2002 CARCINOGENESIS 23(6):1065-1070 Fenton JI; Wolff MS; Orth MW; Hord NG Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype	2	0
634	1	602 2002 CELLULAR SIGNALLING 14(4):351-358 Pauley CJ; Ledwith BJ; Kaplanski C Peroxisome proliferators activate growth regulatory pathways largely via peroxisome proliferator-activated receptor alpha-independent mechanisms	2	0
635	4	606 2002 CURRENT OPINION IN STRUCTURAL BIOLOGY 12(6):761-767 Pearl LH; Barford D Regulation of protein kinases in insulin, growth factor and Wnt signalling	2	0
636	7	621 2002 EXPERIMENTAL CELL RESEARCH 280(1):12-23 Cui HY; Dong M; Sadhu DN; Rosenberg DW Suppression of kinesin expression disrupts adenomatous polyposis coli (APC) localization and affects beta-catenin turnover in young adult mouse colon (YAMC) epithelial cells	2	1
637	11	631 2002 GENES CHROMOSOMES & CANCER 33(1):73-81 Shimizu Y; Ikeda S; Fujimori M; Kodama S; Nakahara M; Okajima M; Asahara T Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability	2	0
638	3	633 2002 GUT 50(4):513-519 Hardy RG; Tselepis C; Hoyland J; Wallis Y; Pretlow TP; Talbot I; Sanders DSA; Matthews G; Morton D; Jankowski JAZ Aberrant P-cadherin expression is an early event in hyperplastic and dlysplastic transformation in the colon	2	1
639	7	639 2002 HORMONE-RELATED TUMORS: NOVEL APPROACHES TO PREVENTION AND TREATMENT 963():21-36 Levy L; Renard CA; Wei Y; Buendia MA Genetic alterations and oncogenic pathways in hepatocellular carcinoma	2	0
640	12	648 2002 INTERNATIONAL JOURNAL OF CANCER 102(4):338-342 Haydon RC; Deyrup A; Ishikawa A; Heck R; Jiang W; Zhou L; Feng T; King D; Chew HW; Breyer B; Peabody T; Simon MA; Montag AG; He TC Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma	2	1
641	9	651 2002 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 10(4):395-399 Kusafuka T; Miao J; Kuroda S; Udatsu Y; Yoneda A Codon 45 of the beta-catenin gene, a specific mutational target site of Wilms' tumor	2	1
642	5	670 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(20):18191-18197 Smith E; Coetzee GA; Frenkel B Glucocorticoids inhibit cell cycle progression in differentiating osteoblasts via glycogen synthase kinase-3 beta	2	0
643	14	671 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(21):18677-18686 Weng ZG; Xin M; Pablo L; Grueneberg D; Hagel M; Bain G; Muller T; Papkoff J Protection against anoikis and down-regulation of cadherin expression by a regulatable beta-catenin protein	2	1
644	8	690 2002 JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY 55(4):220-226 Holcombe RF; Marsh JL; Waterman ML; Lin F; Milovanovic T; Truong T Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma	2	1
645	2	695 2002 JOURNAL OF GASTROINTESTINAL SURGERY 6(4):563-568 Lew JI; Guo Y; Kim RK; Vargish L; Michelassi F; Arenas RB Reduction of intestinal neoplasia with adenomatous polyposis coli gene replacement and COX-2 inhibition is additive	2	0
646	6	698 2002 JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS 7(1):41-45 Koster MI; Huntzinger KA; Roop DR Epidermal differentiation: Transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation	2	0
647	8	700 2002 JOURNAL OF NUTRITION 132(12):3804S-3808S Augenlicht LH; Mariadason JM; Wilson A; Arango D; Yang WC; Heerdt BG; Velcich A Short chain fatty acids and colon cancer	2	0
648	8	710 2002 LABORATORY INVESTIGATION 82(1):97-103 Saito T; Oda Y; Kawaguchi K; Tanaka K; Matsuda S; Tamiya S; Iwamoto Y; Tsuneyoshi M Possible association between higher beta-catenin mRNA expression and mutated beta-catenin in sporadic desmoid tumors: Real-time semiquantitative assay by TaqMan polymerase chain reaction	2	1
649	11	715 2002 MODERN PATHOLOGY 15(10):1032-1037 Schlosshauer PW; Ellenson LH; Soslow RA beta-catenin and E-cadherin expression patterns in high-grade endometrial carcinoma are associated with histological subtype	2	0
650	12	718 2002 MOLECULAR CANCER THERAPEUTICS 1(14):1355-1359 Kim JS; Crooks H; Foxworth A; Waldman T Proof-of-principle: Oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors	2	1
651	3	731 2002 ONCOGENE 21(30):4696-4701 Cullingworth J; Hooper ML; Harrison DJ; Mason J; Sirard C; Patek CE; Clarke AR Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes	2	0
652	10	743 2002 ONCOGENE 21(54):8340-8346 Kwong KY; Zou YY; Day CP; Hung MC The suppression of colon cancer cell growth in nude mice by targeting beta-catenin/TCF pathway	2	0
653	11	744 2002 ONCOGENE 21(55):8414-8427 Jaiswal AS; Marlow BP; Gupta N; Narayan S beta-Catenin-mediated transactivation and cell - cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells	2	1
654	5	755 2002 SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY 37(10):1184-1193 Lovig T; Meling GI; Diep CB; Thorstensen L; Andersen SN; Lothe RA; Rognum TO APC and CTNNB1 mutations in a large series of sporadic colorectal carcinomas stratified by the microsatellite instability status	2	1
655	6	759 2002 TUMOR BIOLOGY 23(1):45-53 Pereira-Suarez AL; Meraz MA; Lizanoc M; Estrada-Chavez C; Hernandez F; Olivera P; Perez E; Padilla P; Yaniv M; Thierry F; Garcia-Carranca A Frequent alterations of the beta-catenin protein in cancer of the uterine cervix	2	0
656	8	785 2003 CANCER RESEARCH 63(4):801-806 Sasaki T; Suzuki H; Yagi K; Furuhashi M; Yao R; Susa S; Noda T; Arai Y; Miyazono K; Kato M Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor beta-induced repression of c-myc	2	0
657	14	786 2003 CANCER RESEARCH 63(8):1906-1913 Howe LR; Watanabe O; Leonard J; Brown AMC Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation	2	1
658	5	805 2003 CARCINOGENESIS 24(1):91-97 Yamada Y; Oyama T; Hirose Y; Hara A; Sugie S; Yoshida K; Yoshimi N; Mori H beta-Catenin mutation is selected during malignant transformation in colon carcinogenesis	2	2
659	2	810 2003 CELLULAR SIGNALLING 15(3):327-338 Denoyelle C; Albanese P; Uzan G; Hong L; Vannier JP; Soria J; Soria C Molecular mechanism of the anti-cancer activity of cerivastatin, an inhibitor of HMG-CoA reductase, on aggressive human breast cancer cells	2	0
660	6	820 2003 CURRENT OPINION IN GENETICS & DEVELOPMENT 13(1):28-33 van Es JH; Barker N; Clevers H You Wnt some, you lose some: oncogenes in the Wnt signaling pathway	2	0
661	3	850 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(2):1380-1387 Ni ZY; Anini Y; Fang XJ; Mills G; Brubakers PL; Jin TR Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cells	2	0
662	16	860 2003 JOURNAL OF CELL SCIENCE 116(5):773-783 Ryo A; Liou YC; Lu KP; Wulf G Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer	2	0
663	9	891 2003 NATURE MEDICINE 9(3):300-306 Fujimuro M; Wu FY; ApRhys C; Kajumbula H; Young DB; Hayward GS; Hayward SD A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency	2	0
664	2	910 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(3):1004-1009 Stappenbeck TS; Mills JC; Gordon JI Molecular features of adult mouse small intestinal epithelial progenitors	2	0
665	2	20 1999 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1450(3):331-340 Wang B; Kishihara K; Zhang DL; Sakamoto T; Nomoto K Transcriptional regulation of a receptor protein tyrosine phosphatase gene hPTP-J by PKC-mediated signaling pathways in Jurkat and Molt-4 T lymphoma cells	1	0
666	1	46 1999 CELL PROLIFERATION 32(2-3):79-84 Del Buono R; Pignatelli M The role of the E-cadherin complex in gastrointestinal cell differentiation	1	0
667	1	105 1999 M S-MEDECINE SCIENCES 15(10):1105-1117 Perrin L; Arquier N; Semeriva M Links between growth rate and proliferation revisited in Drosophila	1	0
668	6	147 1999 TRENDS IN GENETICS 15(12):M53-M56 McCormick F Signalling networks that cause cancer (Reprinted from Trends in Biochemical Sciences, vol 12, Dec., 1999)	1	0
669	1	200 2000 CELLULAR & MOLECULAR BIOLOGY LETTERS 5(1):3-18 Miturski R; Burnouf D; Nothisen M; Bogusiewicz M; Jakowicki JA Molecular biology and clinical implications of the adenomatous polyposis coli (APC) gene	1	0
670	1	202 2000 CHINESE SCIENCE BULLETIN 45(21):1973-1977 Lin GT; Zhang ZW; Zang T; Xin DQ; Chang ZJ; Guo YL Interaction of hTCF4 by yeast two-hybrid system	1	0
671	2	203 2000 CHIRURGISCHE GASTROENTEROLOGIE 16(3):206-212 Muller H; Dobbie Z; Heinimann K Familial colorectal cancer and genetic screening	1	0
672	1	341 2001 ANTICANCER RESEARCH 21(1A):65-70 Sundfeldt K; Ivarsson K; Rask K; Haeger M; Hedin L; Brannstrom M Higher levels of soluble E-cadherin in cyst fluid from malignant ovarian tumours than in benign cysts	1	0
673	12	357 2001 CANCER LETTERS 166(2):185-191 Dimitriadis A; Vincan E; Mohammed IM; Roczo N; Phillips WA; Baindur-Hudson S Expression of Wnt genes in human colon cancers	1	0
674	3	362 2001 CANCER RESEARCH 61(3):854-858 Wakita K; Tetsu O; McCormick F A mammalian two-hybrid system for adenomatous polyposis coli-mutated colon cancer therapeutics	1	0
675	13	396 2001 CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE 12(2):152-165 Lo Muzio L A possible role for the WNT-1 pathway in oral carcinogenesis	1	0
676	6	397 2001 CURRENT OPINION IN GASTROENTEROLOGY 17(1):65-71 DuBois RN Nonsteroidal antiinflammatory drugs, cyclooxygenase-2, and colorectal cancer prevention	1	0
677	2	401 2001 CYTOGENETICS AND CELL GENETICS 93(1-2):26-28 Dong X; Seelan RS; Qian C; Mai M; Liu W Genomic structure, chromosome mapping and expression analysis of the human AXIN2 gene	1	0
678	3	419 2001 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 25(11):967-978 Buecher B; Heymann MF; Blottiere HM Rationale and prospects for the use of cyclooxygenase-2 (COX-2) inhibitors in colorectal cancer	1	0
679	5	426 2001 HEPATOLOGY RESEARCH 21(2):126-135 Murata M; Miyoshi Y; Ohsawa M; Shibata K; Ohta T; Imai Y; Nishikawa M; Iwao K; Tateishi H; Shimano T; Kobayashi T; Nakamura Y Accumulation of beta-catenin in the cytoplasm and the nuclei during the early hepatic tumorigenesis	1	1
680	14	445 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(6):1227-1233 Williams CL; Noti JD Reduced expression of Wnt-1 and E-cadherin, and diminished beta-catenin stability in MCF-7 breast cancer cells that overexpress protein kinase C-alpha	1	0
681	1	460 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(48):45168-45174 Jiang W; Zhou L; Breyer B; Feng T; Cheng HW; Haydon R; Ishikawa A; He TC Tetracycline-regulated gene expression mediated by a novel chimeric repressor that recruits histone deacetylases in mammalian cells	1	0
682	7	488 2001 JOURNAL OF PEPTIDE RESEARCH 58(6):493-503 Catimel B; Faux MC; Nerrie M; Rothacker J; Otvos L; Wade JD; Nice EC; Burgess AW The use of coiled-coil interactions for the analysis and micropreparative isolation of adenomatous polyposis coli protein complexes	1	0
683	8	539 2001 PATHOLOGY INTERNATIONAL 51(9):680-685 Miyake N; Maeta H; Horie S; Kitamura Y; Nanba E; Kobayashi K; Terada T Absence of mutations in the beta-catenin and adenomatous polyposis coli genes in papillary and follicular thyroid carcinomas	1	1
684	4	558 2002 AMERICAN JOURNAL OF PATHOLOGY 161(5):1735-1742 Abraham SC; Park SJ; Mugartegui L; Hamilton SR; Wu TT Sporadic fundic gland polyps with epithelial dysplasia - Evidence for preferential targeting for mutations in the adenomatous polyposis coli gene	1	0
685	6	564 2002 ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE 126(9):1071-1078 Sakamoto A; Oda Y; Adachi T; Saito T; Tamiya S; Iwamoto Y; Tsuneyoshi M beta-Catenin accumulation and gene mutation in exon 3 in dedifferentiated liposarcoma and malignant fibrous histiocytoma	1	1
686	3	568 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 299(5):806-812 Lim HW; Lee JE; Shin SJ; Lee YE; Oh SH; Park JY; Seong JK; Park JS Identification of differentially expressed mRNA during pancreas regeneration of rat by mRNA differential display	1	0
687	11	575 2002 BIOTECHNIQUES 33(5):1126-+ Zhou L; An N; Jiang W; Haydon R; Cheng H; Zhou Q; Breyer B; Feng T; He TC Fluorescence-based functional assay for Wnt/beta-catenin signaling activity	1	1
688	17	576 2002 BLOOD 100(3):982-990 Chung EJ; Hwang SG; Nguyen P; Lee S; Kim JS; Kim JW; Henkart PA; Bottaro DP; Soon L; Bonvini P; Lee SJ; Karp JE; Oh HJ; Rubin JS; Trepel JB Regulation of leukemic cell adhesion, proliferation, and survival by beta-catenin	1	1
689	4	580 2002 BRITISH MEDICAL BULLETIN 64():27-43 Fearnhead NS; Wilding JL; Bodmer WF Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis	1	0
690	1	588 2002 CANCER GENETICS AND CYTOGENETICS 135(1):48-56 Moritake H; Sugimoto T; Asada Y; Yoshida MA; Maehara Y; Epstein AL; Kuroda H Newly established clear cell sarcoma (malignant melanoma of soft parts) cell line expressing melanoma-associated Melan-A antigen and overexpressing C-MYC oncogene	1	0
691	2	591 2002 CANCER LETTERS 183(1):31-41 Suzui M; Okuno M; Tanaka T; Nakagama H; Moriwaki H Enhanced colon carcinogenesis induced by azoxymethane in min mice occurs via a mechanism independent of beta-catenin mutation	1	0
692	7	592 2002 CANCER LETTERS 183(1):95-101 Howng SL; Wu CH; Cheng TS; Sy WD; Lin PCK; Wang CH; Hong YR Differential expression of Wnt genes, beta-catenin and E-cadherin in human brain tumors	1	0
693	10	604 2002 CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 41(1):11-28 Mason MD; Davies G; Jiang WG Cell adhesion molecules and adhesion abnormalities in prostate cancer	1	0
694	59	609 2002 DIGESTION 66(3):131-144 Kolligs FT; Bommer G; Goke B Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis	1	0
695	25	617 2002 EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 32(6):448-457 Oving IM; Clevers HC Molecular causes of colon cancer	1	1
696	6	620 2002 EXPERIMENTAL CELL RESEARCH 278(1):19-30 Hackett L; Davies D; Helyer R; Kennedy H; Kros C; Lawlor P; Rivolta MN; Holley M E-cadherin and the differentiation of mammalian vestibular hair cells	1	0
697	4	622 2002 EXPERIMENTAL CELL RESEARCH 280(1):33-44 Marcelo P; Lefevre F Induction of the IFN-gamma gene and protein is linked to the establishment of cell polarity in a porcine epithelial cell line	1	0
698	7	628 2002 GASTROENTEROLOGY 123(3):935-939 Yang VW APC as a checkpoint gene: The beginning or the end?	1	0
699	6	641 2002 HUMAN PATHOLOGY 33(8):852-855 Takayasu H; Motoi T; Kanamori Y; Kitano Y; Nakanishi H; Tange T; Nakagawara A; Hashizume K Two case reports of childhood liver cell adenomas harboring beta-catenin abnormalities	1	0
700	5	678 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(40):37479-37486 Karasawa T; Yokokura H; Kitajewski J; Lombroso PJ Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta-catenin signaling	1	0

#	Cited nodes	Nodes / Authors	GCS	LCS
701	16	680 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(48):45847-45853 Holnthoner W; Pillinger M; Groger M; Wolff K; Ashton AW; Albanese C; Neumeister P; Pestell RG; Petzelbauer P Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells	1	0
702	12	685 2002 JOURNAL OF CELL SCIENCE 115(13):2771-2780 Sadot E; Conacci-Sorrell M; Zhurinsky J; Shnizer D; Lando Z; Zharhary D; Kam Z; Ben-Ze'ev A; Geiger B Regulation of S33/S37 phosphorylated beta-catenin in normal and transformed cells	1	0
703	3	688 2002 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 87(7):3475-3485 Demeterco C; Itkin-Ansari P; Tyrberg B; Ford LP; Jarvis RA; Levine F c-Myc controls proliferation versus differentiation in human pancreatic endocrine cells	1	0
704	5	692 2002 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 21(1):23-27 Kawakami M; Kimura Y; Furuhata T; Zenbutsu H; Yanai Y; Mukaiya M; Satoh Y; Murata S; Hirata K beta-catenin alteration in cancer of the ampulla of Vater	1	1
705	8	714 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(12):1665-1680 Lim IK Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats	1	1
706	1	717 2002 MOLECULAR AND CELLULAR BIOLOGY 22(15):5467-5478 Boudreau F; Rings EHHM; Swain GP; Sinclair AM; Suh ER; Silberg DG; Scheuermann RH; Traber PG A novel colonic repressor element regulates intestinal gene expression by interacting with Cux/CDP	1	0
707	4	723 2002 MOLECULAR CELL 10(6):1260-1261 Clevers H Inflating cell numbers by Wnt	1	1
708	7	724 2002 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 506():137-144 Nakagama H; Ochiai M; Ubagai T; Tajima R; Fujiwara K; Sugimura T; Nagao M A rat colon cancer model induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, PhIP	1	0
709	13	736 2002 ONCOGENE 21(41):6387-6394 Ishiguro H; Shimokawa T; Tsunoda T; Tanaka T; Fujii Y; Nakamura Y; Furukawa Y Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas	1	0
710	15	738 2002 ONCOGENE 21(46):6983-6991 Aoki M; Sobek V; Maslyar DJ; Hecht A; Vogt PK Oncogenic transformation by beta-catenin: deletion analysis and characterization of selected target genes	1	1
711	9	739 2002 ONCOGENE 21(49):7497-7506 Winn RA; Bremnes RM; Bemis L; Franklin WA; Miller YE; Cool C; Heasley LE gamma-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth	1	0
712	20	740 2002 ONCOGENE 21(52):7971-7980 Cagatay T; Ozturk M p53 mutation as a source of aberrant beta-catenin accumulation in cancer cells	1	0
713	5	747 2002 ORAL ONCOLOGY 38(1):64-72 Lo Muzio L; Pannone G; Staibano S; Mignogna MD; Serpico R; Fanali S; De Rosa G; Piattelli A; Mariggio MA p120(cat) delocalization in cell lines of oral cancer	1	0
714	3	754 2002 SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY 37(9):1048-1053 De Filippo C; Luceri C; Caderni G; Pacini M; Messerini L; Biggeri A; Mini E; Tonelli F; Cianchi F; Dolara P Mutations of the APC gene in human sporadic colorectal cancers	1	0
715	6	758 2002 TOXICOLOGY AND APPLIED PHARMACOLOGY 182(3):255-265 Prozialeck WC; Grunwald GB; Dey PM; Reuhl KR; Parrish AR Cadherins and NCAM as potential targets in metal toxicity	1	0
716	12	763 2002 WORLD JOURNAL OF GASTROENTEROLOGY 8(5):804-807 Jiang Y; Zhou XD; Liu YK; Wu X; Huang XW Association of hTcf-4 gene expression and mutation with clinicopathological characteristics of hepatocellular carcinoma	1	0
717	8	768 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 303(1):212-218 Biswas P; Canosa S; Schoenfeld J; Schoenfeld D; Tucker A; Madri JA PECAM-1 promotes beta-catenin accumulation and stimulates endothelial cell proliferation	1	0
718	70	773 2003 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1653(1):1-24 Giles RH; van Es JH; Clevers H Caught up in a Wnt storm: Wnt signaling in cancer	1	0
719	19	776 2003 BREAST CANCER RESEARCH 5(2):63-68 Miyoshi K; Hennighausen L beta-catenin: a transforming actor on many stages	1	0
720	5	808 2003 CELL DEATH AND DIFFERENTIATION 10(5):528-538 Lacher MD; Siegenthaler A; Jager R; Yan X; Hett S; Xuan L; Saurer S; Lareu R; Dharmarajan AM; Friis R Role of DDC-4/sFRP-4, a secreted Frizzled-related protein, at the onset of apoptosis in mammary involution	1	0
721	3	811 2003 CLINICAL & EXPERIMENTAL METASTASIS 20(1):85-90 Yeatman TJ; Chambers AF Osteopontin and colon cancer progression	1	0
722	7	814 2003 CLINICAL CANCER RESEARCH 9(3):931-946 Williams NS; Gaynor RB; Scoggin S; Verma U; Gokaslan T; Simmang C; Fleming J; Tavana D; Frenkel E; Becerra C Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference	1	0
723	1	822 2003 DEVELOPMENT 130(7):1367-1379 Chen W; Liang YQ; Deng WJ; Shimizu K; Ashique AM; Li E; Li YP The zinc-finger protein CNBP is required for forebrain formation in the mouse	1	1
724	2	826 2003 DEVELOPMENTAL CELL 4(6):827-839 Bellmeyer A; Krase J; Lindgren J; LaBonne C The protooncogene c-Myc is an essential regulator of neural crest formation in Xenopus	1	1
725	7	830 2003 EMBO REPORTS 4(2):166-171 Civenni G; Holbro T; Hynes NE Wnt1 and Wnt5a induce cyclin D1 expression through ErbB1 transactivation in HC11 mammary epithelial cells	1	0
726	4	832 2003 EXPERIMENTAL CELL RESEARCH 285(1):131-145 Coppe JP; Smith AP; Desprez PY Id proteins in epithelial cells	1	0
727	1	834 2003 GENE 307():51-62 Shimizu K; Chen W; Ashique AM; Moroi R; Li YP Molecular cloning, developmental expression, promoter analysis and functional characterization of the mouse CNBP gene	1	0
728	11	836 2003 GENES & DEVELOPMENT 17(10):1189-1200 Alonso L; Fuchs E Stem cells in the skin: waste not, Wnt not	1	0
729	5	838 2003 GYNECOLOGIC ONCOLOGY 88(3):363-368 Lee CM; Shvartsman H; Deavers MT; Wang SC; Xia WY; Schmandt R; Bodurka DC; Atkinson EN; Malpica A; Gershenson DM; Hung MC; Lu KH beta-Catenin nuclear localization is associated with grade in ovarian serous carcinoma	1	0
730	5	839 2003 HEPATOLOGY 37(3):528-533 Yamamoto Y; Sakamoto M; Fujii G; Tsuiji H; Kanetaka K; Asaka M; Hirohashi S Overexpression of orphan G-Protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations	1	0
731	4	841 2003 IMMUNITY 19(2):169-182 Chi TH; Wan MM; Lee PP; Akashi K; Metzger D; Chambon P; Wilson CB; Crabtree GR Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development	1	0
732	1	858 2003 JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME 85A(8):1544-1552 Cheng HW; Jiang W; Phillips FM; Haydon RC; Peng Y; Zhou L; Luu HH; An NL; Breyer B; Vanichakarn P; Szatkowski JP; Park JY; He TC Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)	1	0
733	68	859 2003 JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 129(4):199-221 Lustig B; Behrens J The Wnt signaling pathway and its role in tumor development	1	0
734	10	869 2003 JOURNAL OF PATHOLOGY 199(1):68-76 Koesters R; Niggli F; Doeberitz MV; Stallmach T Nuclear accumulation of beta-catenin protein in Wilms' tumours	1	0
735	9	875 2003 LANCET 362(9379):205-209 Kim PJ; Plescia J; Clevers H; Fearon ER; Altieri DC Survivin and molecular pathogenesis of colorectal cancer	1	0
736	7	877 2003 LIFE SCIENCES 72(11):1303-1320 Pearson CA; Lamar PC; Prozialeck WC Effects of cadmium on E-cadherin and VE-cadherin in mouse lung	1	0
737	12	885 2003 MOLECULAR BIOLOGY OF THE CELL 14(2):585-599 Albanese C; Wu KM; D'Amico M; Jarrett C; Joyce D; Hughes J; Hulit J; Sakamaki T; Fu MF; Ben-Ze'ev A; Bromberg JF; Lamberti C; Verma U; Gaynor RB; Byers SW; Pestell RG IKK alpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf	1	0
738	11	887 2003 MOLECULAR CANCER THERAPEUTICS 2(1):113-121 Kirmizis A; Bartley SM; Farnham PJ Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy	1	0
739	5	892 2003 NATURE REVIEWS NEUROSCIENCE 4(10):795-805 Gammill LS; Bronner-Fraser M Neural crest specification: Migrating into genomics	1	0
740	7	896 2003 ONCOGENE 22(9):1324-1332 Schroeder JA; Adriance MC; Thompson MC; Camenisch TD; Gendler SJ MUC1 alters beta-catenin-dependent tumor formation and promotes cellular invasion	1	0
741	9	905 2003 ORGANIC LETTERS 5(16):2927-2930 Hale KJ; Domostoj MM; Tocher DA; Irving E; Scheinmann F Enantiospecific formal total synthesis of the tumor and GSK-3 beta inhibiting alkaloid, (-)-agelastatin A	1	0
742	7	912 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(13):7859-7864 Martinez ME; O'Brien TG; Fultz KE; Babbar N; Yerushalmi H; Qu N; Guo YJ; Boorman D; Einspahr J; Alberts DS; Gerner EW Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene	1	0
743	5	913 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(15):8752-8757 Nakayama K; Hatakeyama S; Maruyama S; Kikuchi A; Onoe K; Good RA; Nakayama KI Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene	1	0
744	6	914 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(16):9524-9529 Baluchamy S; Rajabi HN; Thimmapaya R; Navaraj A; Thimmapaya B Repression of c-Myc and inhibition of G(1) exit in cells conditionally overexpressing p300 that is not dependent on its histone acetyltransferase activity	1	0
745	2	918 2003 TRENDS IN CELL BIOLOGY 13(3):146-150 Wanzel M; Herold S; Eilers M Transcriptional repression by Myc	1	0
746	1	6 1998 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 22(12):1071-1080 Jais P; Laurent-Puig P; Olschwang S APC protein: protein interactions and cellular functions	0	0
747	3	24 1999 BULLETIN DU CANCER 86(4):336-336 Jeanteur P beta-catenin, APC, C-MYC and the others...	0	0
748	1	57 1999 CURRENT OPINION IN GASTROENTEROLOGY 15(1):3-8 Shattuck-Brandt RL; DuBois RN The molecular basis of colorectal carcinogenesis	0	0
749	1	99 1999 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 84(4):1491-1492 Stratakis CA Carney complex and related syndromes and their genetic loci - Response	0	0
750	2	104 1999 M S-MEDECINE SCIENCES 15(3):427-428 L'Allemain G The WISP genes, a family of novel connective tissue growth factors, are dysregulated in Wnt-1-transformed cells and in human colon cancer.	0	0
751	2	141 1999 SCIENTIST 13(14):15-15 Kinzler KW Hot papers - Cancer - Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC by P.J. Morin, A.B. Sparks, V. Korinek, N. Barker, H. Clevers, B. Vogelstein, K.W. Kinzler - Comments	0	0
752	1	142 1999 SCIENTIST 13(8):15-15 Birchmeier W Hot papers - Cell biology - Functional interaction of beta-catenin with the transcription factor LEF-I by J. Behrens, J.P. von Kries, M. Kuhl, L. Bruhn, D. Wedlich, R. Grosschedl, W. Birchmeier - Comments	0	0
753	1	143 1999 SCIENTIST 13(2):24-24 [Anon] Serial analysis of gene expression: An alternative to chip arrays	0	0
754	2	204 2000 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 65():511-520 Wahl G; Vafa O Genetic instability, oncogenes, and the p53 pathway	0	0
755	2	244 2000 HARVEY LECTURES, SERIES 94, 1998-1999 94():47-+ Fuchs E Beauty is skin deep: The fascinating biology of the epidermis and its appendages	0	0
756	1	282 2000 JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 28(3):113-127 Napierala D; Plawski A; Kalak R; Jura J; Wronka J; Sowinska J; Banasiewicz T; Slomski R Molecular diagnostics of genetic diseases: Experience from studies of DMD, APC, TSC1, and OPG genes. Part 1	0	0
757	1	318 2000 ONCOLOGY REPORTS 7(4):707-712 Kim HJ; Guo WT; Park NH HPV-16 E6 oncoprotein induces mutations via p53-dependent and -independent pathways	0	0
758	3	326 2000 SCIENTIST 14(11):20-21 Halim NS Hot papers - Converging pathways - Comment	0	0
759	4	333 2001 ACTA GASTRO-ENTEROLOGICA BELGICA 64(3):249-254 Tejpar S; Cassiman JJ; Van Cutsem E The molecular basis of colorectal cancer	0	0
760	3	337 2001 AMERICAN JOURNAL OF DERMATOPATHOLOGY 23(6):521-524 Nishie W; Iitoyo M; Miyazawa H Follicular cyst in a patient with myotonic dystrophy - A case of cyst with differentiation toward follicular infundibulum, isthmus, inner root sheath, and hair	0	0
761	2	354 2001 CANCER 91(1):42-48 Semba S; Han SY; Ikeda H; Horii A Frequent nuclear accumulation of beta-catenin in pituitary adenoma	0	2
762	5	358 2001 CANCER LETTERS 168(1):1-6 Kubozoe TO; Tsujiuchi T; Murata N; Sasaki Y; Tsunoda T; Konishi Y; Tsutsumi R Absence of beta-catenin gene mutations in pancreatic duct lesions induced by N-nitrosobis(2-oxopropyl)amine in hamsters	0	0
763	4	409 2001 ENDOCRINE PATHOLOGY 12(1):1-13 Semba S; Yamakawa M; Sasano H The cadherin-catenin superfamily in endocrine tumors	0	0
764	4	446 2001 INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY 9(4):273-279 Lifschitz-Mercer B; Amitai R; Maymon BBS; Shechtman L; Czernobilsky B; Leider-Trejo L; Ben-Ze'ev A; Geiger B Nuclear localization of beta-catenin and plakoglobin in primary and metastatic human colonic carcinomas, colonic adenomas, and normal colon	0	0
765	4	478 2001 JOURNAL OF GASTROENTEROLOGY 36(9):587-594 Fujimori T; Kawamata H; Kashida H Precancerous lesions of the colorectum	0	0
766	17	480 2001 JOURNAL OF IMMUNOLOGY 167(12):6786-6793 Thiele A; Wasner M; Muller C; Engeland K; Hauschildt S Regulation and possible function of beta-catenin in human monocytes	0	0
767	8	535 2001 ONCOGENE 20(52):7645-7657 Hollmann CA; Kittrell FS; Medina D; Butel JS Wnt-1 and int-2 mammary oncogene effects on the beta-catenin pathway in immortalized mouse mammary epithelial cells are not sufficient for tumorigenesis	0	0
768	2	560 2002 ANNALES DE PATHOLOGIE 22(4):277-288 Piard F; Martin L; Chapusot C; Ponnelle T; Faivre J Genetic pathways in colorectal cancer: interest for the pathologist	0	0
769	5	563 2002 ANTICANCER RESEARCH 22(6A):3409-3414 D'Orazio D; Muller PY; Heinimann K; Albrecht C; Bendik I; Herzog U; Tondelli P; Bauerfeind P; Muller H; Dobbie Z Overexpression of Wnt target genes in adenomas of familial adenomatous polyposis patients	0	0
770	5	565 2002 BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY 16(2):171-185 Tejpar S; Van Cutsem E Molecular and genetic defects in colorectal tumorigenesis	0	0
771	5	567 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 299(5):744-750 Meredith JE; Wang Q; Mitchell TJ; Olson RE; Zaczek R; Stern AM; Seiffert D gamma-Secretase activity is not involved in presenilin-mediated regulation of beta-catenin	0	0
772	11	569 2002 BIOCHEMICAL JOURNAL 367():723-728 Chtarbova S; Nimmrich I; Erdmann S; Herter P; Renner M; Kitajewski J; Muller O Murine Nr4a1 and Herpud1 are up-regulated by Wnt-1, but the homologous human genes are independent from beta-catenin activation	0	0
773	8	577 2002 BREAST CANCER RESEARCH 5(1):16-22 Rossi S; Loda M The role of the ubiquitination-proteasome pathway in breast cancer - Use of mouse models for analyzing ubiquitination processes	0	0
774	9	578 2002 BRITISH JOURNAL OF CANCER 86(7):1124-1129 Chiang JM; Chou YHW; Chen TC; Ng KF; Lin JL Nuclear beta-catenin expression is closely related to ulcerative growth of colorectal carcinoma	0	0
775	10	581 2002 CANCER 95(12):2479-2486 Cheah PY; Choo PH; Yao J; Eu KW; Seow-Choen F A survival-stratification model of human colorectal carcinomas with beta-catenin and p27(kip1)	0	0
776	2	582 2002 CANCER BIOLOGY & THERAPY 1(1):58-63 Termuhlen PM; Sweeney-Gotsch BM; Berman RS; Ellis LM; Bucana C; Shen Y; Cleary KR; McConkey DJ Increased apoptosis in metastatic human colonic adenocarcinomas	0	0
777	3	583 2002 CANCER BIOLOGY & THERAPY 1(6):640-645 Coyle-Rink J; Del Valle L; Sweet T; Khalili K; Amini S Developmental expression of Wnt signaling factors in mouse brain	0	0
778	18	605 2002 CURRENT OPINION IN GASTROENTEROLOGY 18(1):53-59 Waterman ML Expression of lymphoid enhancer factor/T-cell factor proteins in colon cancer	0	0
779	8	610 2002 DIGESTIVE DISEASES AND SCIENCES 47(12):2738-2742 Saeki H; Tanaka S; Sugimachi K; Kimura Y; Miyazaki M; Ohga T; Sugimachi K Interrelation between expression of matrix metalloproteinase 7 and beta-catenin in esophageal cancer	0	0
780	6	615 2002 EUROPEAN JOURNAL OF CANCER PREVENTION 11():S12-S17 Augenlicht LH; Heerdt BG; Mariadason JM; Yang WC; Wilson AJ; Fragale A; Velcich A Environment-gene interactions in intestinal cancer	0	0
781	2	616 2002 EUROPEAN JOURNAL OF CANCER PREVENTION 11(1):85-97 Piard F; Chapusot C; Ecarnot-Laubriet A; Ponnelle T; Martin L Molecular markers of heterogeneity in colorectal cancers and adenomas	0	0
782	1	618 2002 EUROPEAN JOURNAL OF HUMAN GENETICS 10(10):631-637 Ripa R; Bisgaard ML; Bulow S; Nielsen FC De novo mutations in familial adenomatous polyposis (FAP)	0	0
783	4	619 2002 EXPERIMENTAL AND MOLECULAR MEDICINE 34(6):444-450 Shin SY; Yoon SC; Kim YH; Kim YS; Lee YH Phosphorylation of glycogen synthase kinase-3 beta at serine-9 by phospholipase C gamma 1 through protein kinase C in rat 3Y1 fibroblasts	0	0
784	3	624 2002 FEBS LETTERS 530(1-3):147-152 Stone CD; Chen ZY; Tseng CC Gut-enriched Kruppel-like factor regulates colonic cell growth through APC/beta-catenin pathway	0	0
785	3	635 2002 GUT 50(6):845-850 Moisio AL; Jarvinen H; Peltomaki P Genetic and clinical characterisation of familial adenomatous polyposis: a population based study	0	0
786	31	637 2002 HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA 16(4):775-+ Lynch JP; Hoops TC The genetic pathogenesis of colorectal cancer	0	0
787	3	638 2002 HEPATOLOGY 36(6):1528-1536 Desbois-Mouthon C; Eggelpoel MJBV; Beurel E; Boissan M; Delelo R; Cadoret A; Capeau J Dysregulation of glycogen synthase kinase-3 beta signaling in hepatocellular carcinoma cells	0	0
788	10	642 2002 INFECTION AND IMMUNITY 70(5):2605-2613 Prozialeck WC; Fay MJ; Lamar PC; Pearson CA; Sigar I; Ramsey KH Chlamydia trachomatis disrupts N-cadherin-dependent cell-cell junctions and sequesters beta-catenin in human cervical epithelial cells	0	0
789	2	647 2002 INTERNATIONAL JOURNAL OF CANCER 102(1):60-69 Melkoumian ZK; Martirosyan AR; Strobl JS Myc protein is differentially sensitive to quinidine in tumor versus immortalized breast epithelial cell lines	0	0
790	2	649 2002 INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 46(4):653-660 Tan SS; Gunnersen J; Job C Global gene expression analysis of developing neocortex using SAGE	0	0
791	4	650 2002 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 9(5):489-493 Masui O; Ueda Y; Tsumura A; Koyanagi M; Hijikata M; Shimotohno K RelA suppresses the Wnt/beta-catenin pathway without exerting trans-acting transcriptional ability	0	0
792	2	656 2002 INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 219 219():157-198 Vikhanskaya F; Broggini M Genetic alterations in ovarian cancer cells that might account for sensitivity to chemotherapy in patients	0	0
793	1	657 2002 JAPANESE JOURNAL OF CANCER RESEARCH 93(3):267-274 Nakatsuka S; Hongyo T; Syaifudin M; Nomura T; Shingu N; Aozasa K Mutations of p53, c-kit, K-ras, and beta-catenin gene in non-Hodgkin's lymphoma of adrenal gland	0	0
794	8	658 2002 JAPANESE JOURNAL OF CANCER RESEARCH 93(11):1213-1220 Ikenoue T; Ijichi H; Kato N; Kanai F; Masaki T; Rengifo W; Okamoto M; Matsumura M; Kawabe T; Shiratori Y; Omata M Analysis of the beta-catenin/T cell factor signaling pathway in 36 gastrointestinal and liver cancer cells	0	0
795	5	659 2002 JAPANESE JOURNAL OF CLINICAL ONCOLOGY 32(9):358-362 Koyama T; Tago K; Nakamura T; Ohwada S; Morishita Y; Yokota J; Akiyama T Mutation and expression of the beta-catenin-interacting protein ICAT in human colorectal tumors	0	0
796	7	684 2002 JOURNAL OF CELL SCIENCE 115(13):2639-2650 Relchelt J; Magin TM Hyperproliferation, induction of c-Myc and 14-3-3 sigma, but no cell fragility in keratin-10-null mice	0	0
797	2	691 2002 JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY 55(6):385-388 Salovaara R; Roth S; Loukola A; Launonen V; Sistonen P; Avizienyte E; Kristo P; Jarvinen H; Souchelnytskyi S; Sarlomo-Rikala M; Aaltonen LA Frequent loss of SMAD4/DPC4 protein in colorectal cancers (Reprinted from Gut, vol 51, pg 56-59, 2002)	0	0
798	2	693 2002 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 21(2):203-211 Kishimoto Y; Morisawa T; Hosoda A; Shiota G; Kawasaki H; Hasegawa J Molecular changes in the early stage of colon carcinogenesis in rats treated with azoxymethane	0	0
799	9	699 2002 JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA 7(4):415-432 Jechlinger M; Grunert S; Beug H Mechanisms in epithelial plasticity and metastasis: Insights from 3D cultures and expression profiling	0	0
800	8	701 2002 JOURNAL OF ORAL PATHOLOGY & MEDICINE 31(7):385-394 Gasparoni A; Chaves A; Fonzi L; Johnson GK; Schneider GB; Squier CA Subcellular localization of beta-catenin in malignant cell lines and squamous cell carcinomas of the oral cavity	0	0

#	Cited nodes	Nodes / Authors	GCS	LCS
801	4	703 2002 JOURNAL OF PATHOLOGY 197(2):194-200 Hardy RG; Brown RM; Miller SJ; Tselepis C; Morton DG; Jankowski JAZ; Sanders DSA Transient P-cadherin expression in radiation proctitis; a model of mucosal injury and repair	0	0
802	5	709 2002 JOURNAL OF UROLOGY 168(5):2220-2226 Shiina H; Igawa M; Shigeno K; Terashima M; Deguchi M; Yamanaka M; Ribeiro L; Kane CJ; Dahiya R beta-catenin mutations correlate with over expression of c-myc and cyclin D1 genes in bladder cancer	0	0
803	2	712 2002 LEUKEMIA RESEARCH 26(9):863-871 Hwang SG; Lee HC; Trepel JB; Jeon BH Anticancer drugs-induced apoptotic cell death in leukemia cells is associated with proteolysis of beta-catenin	0	0
804	4	725 2002 NATURE 420(6913):274-277 Peifer M Developmental biology - Colon construction	0	0
805	8	726 2002 NEUROSURGERY 51(1):227-233 von Koch CS; Gulati M; Aldape K; Berger MS Familial medulloblastoma: Case report of one family and review of the literature	0	0
806	8	733 2002 ONCOGENE 21(36):5643-5648 Zhuang SM; Wiseman RW; Soderkvist P Frequent mutations of the Trp53, Hras1 and beta-catenin (Catnb) genes in 1,3-butadiene-induced mammary adenocarcinomas in B6C3F1 mice	0	0
807	8	742 2002 ONCOGENE 21(54):8293-8301 Cadoret A; Ovejero C; Terris B; Souil E; Levy L; Lamers WH; Kitajewski J; Kahn A; Perret C New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism	0	0
808	9	746 2002 ONCOLOGY REPORTS 9(6):1197-1203 Ueta T; Ikeguchi M; Hirooka Y; Kaibara N; Terada T beta-catenin and cyclin D1 expression in human hepatocellular carcinoma	0	0
809	7	748 2002 ORAL ONCOLOGY 38(8):772-778 Sato K; Okazaki Y; Tonogi M; Tanaka Y; Yamane G Expression of beta-catenin in rat oral epithelial dysplasia induced by 4-nitroquinoline 1-oxide	0	0
810	3	757 2002 SURGERY 131(4):384-392 Fransen K; Dimberg J; Osterstrom A; Olsson A; Soderkvist P; Sirsjo A Nitric oxide synthase 2 mRNA expression in relation to p53 and adenomatous polyposis coli mutations in primary colorectal adenocarcinomas	0	0
811	12	764 2003 AMERICAN JOURNAL OF PATHOLOGY 163(2):653-661 Nawrocki-Raby B; Gilles C; Polette M; Martinella-Catusse C; Bonnet N; Puchelle E; Foidart JM; van Roy F; Birembaut P E-cadherin mediates MMP down-regulation in highly invasive bronchial tumor cells	0	0
812	9	765 2003 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 285(1):G217-G222 Song DH; Rana B; Wolfe JR; Crimmins G; Choi C; Albanese C; Wang TC; Pestell RG; Wolfe MM Gastrin-induced gastric adenocarcinoma growth is mediated through cyclin D1	0	0
813	5	766 2003 ANNALS OF SURGICAL ONCOLOGY 10(3):284-290 Lowy AM; Fenoglio-Preiser C; Kim OJ; Kordich J; Gomez A; Knight J; James L; Groden J Dysregulation of beta-catenin expression correlates with tumor differentiation in pancreatic duct adenocarcinoma	0	0
814	5	767 2003 ANTICANCER RESEARCH 23(2B):1489-1493 Bitzer M; Stahl M; Arjumand J; Rees M; Klump B; Heep H; Gabbert HE; Sarbia M C-MYC gene amplification in different stages of oesophageal squamous cell carcinoma: Prognostic value in relation to treatment modality	0	0
815	12	769 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 308(2):227-233 Yasuda J; Tsuchiya A; Yamada T; Sakamoto M; Sekiya T; Hirohashi S Nemo-like kinase induces apoptosis in DLD-1 human colon cancer cells	0	0
816	4	770 2003 BIOCHEMICAL JOURNAL 375():465-470 Qu N; Ignatenko NA; Yamauchi P; Stringer DE; Levenson C; Shannon P; Perrin S; Gerner EW Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine	0	0
817	6	771 2003 BIOCHEMICAL PHARMACOLOGY 66(2):179-189 Harwood AJ; Agam G Search for a common mechanism of mood stabilizers	0	0
818	8	772 2003 BIOCHEMICAL SOCIETY TRANSACTIONS 31():388-392 Babbar N; Gerner EW Polyamines as modifiers of genetic risk factors in human intestinal cancers	0	0
819	12	774 2003 BMC MOLECULAR BIOLOGY 4():- Cong F; Zhang JX; Pao W; Zhou PB; Varmus H A protein knockdown strategy to study the function of beta-catenin in tumorigenesis	0	0
820	2	775 2003 BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH 36(8):975-985 Cerutti JM; Riggins GJ; de Souza SJ What can digital transcript profiling reveal about human cancers?	0	0
821	2	777 2003 BRITISH JOURNAL OF CANCER 88(10):1560-1565 Yu J; Leung WK; Ebert MPA; Leong RWL; Tse PCH; Chan MWY; Bai AHC; To KF; Malfertheiner P; Sung JJY Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer	0	0
822	11	778 2003 BRITISH JOURNAL OF CANCER 88(11):1734-1739 Nakajima M; Fukuchi M; Miyazaki T; Masuda N; Kato H; Kuwano H Reduced expression of Axin correlates with tumour progression of oesophageal squamous cell carcinoma	0	0
823	12	779 2003 BRITISH JOURNAL OF CANCER 88(11):1755-1762 Marotta A; Parhar K; Owen D; Dedhar S; Salh B Characterisation of integrin-linked kinase signalling in sporadic human colon cancer	0	0
824	3	780 2003 BRITISH JOURNAL OF CANCER 89(1):152-157 Yamamoto T; Konishi K; Yamochi T; Makino R; Kaneko K; Shimamura T; Ota H; Mitamura K No major tumorigenic role for beta-catenin in serrated as opposed to conventional colorectal adenomas	0	0
825	5	781 2003 BRITISH JOURNAL OF DERMATOLOGY 148(5):964-970 El-Bahrawy M; El-Masry N; Alison M; Poulsom R; Fallowfield M Expression of beta-catenin in basal cell carcinoma	0	0
826	17	782 2003 CANCER LETTERS 193(2):161-170 Zhou L; An NL; Haydon RC; Zhou QX; Cheng HW; Peng Y; Jiang W; Luu HH; Vanichakarn P; Szatkowski JP; Park JY; Breyer B; He TC Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity	0	0
827	9	783 2003 CANCER LETTERS 196(1):1-12 Dixelius J; Cross MJ; Matsumoto T; Claesson-Welsh L Endostatin action and intracellular signaling: beta-catenin as a potential target?	0	0
828	11	787 2003 CANCER RESEARCH 63(10):2658-2664 Gilles C; Polette M; Mestdagt M; Nawrocki-Raby B; Ruggeri P; Birembaut P; Foidart JM Transactivation of vimentin by beta-catenin in human breast cancer cells	0	0
829	21	788 2003 CANCER RESEARCH 63(11):2913-2922 Schwartz DR; Wu R; Kardia SLR; Levin AM; Huang CC; Shedden KA; Kuick R; Misek DE; Hanash SM; Taylor JMG; Reed H; Hendrix N; Zhai Y; Fearon ER; Cho KR Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas	0	0
830	12	789 2003 CANCER RESEARCH 63(12):3145-3153 Easwaran V; Lee SH; Inge L; Guo L; Goldbeck C; Garrett E; Wiesmann M; Garcia PA; Fuller JH; Chan V; Randazzo F; Gundel R; Warren RS; Escobedo J; Aukerman SL; Taylor RN; Fantl WJ beta-catenin regulates vascular endothelial growth factor expression in colon cancer	0	0
831	4	790 2003 CANCER RESEARCH 63(15):4368-4374 Chen TA; Yang I; Irby R; Shain KH; Wang HG; Quackenbush J; Coppola D; Cheng JQ; Yeatman TJ Regulation of caspase expression and apoptosis by adenomatous polyposis coli	0	0
832	6	791 2003 CANCER RESEARCH 63(15):4547-4551 Uematsu K; Kanazawa S; You L; He B; Xu ZD; Li K; Peterlin BM; McCormick F; Jablons DM Wnt pathway activation in mesothelioma: Evidence of dishevelled overexpression and transcriptional activity of beta-catenin	0	0
833	6	792 2003 CANCER RESEARCH 63(15):4641-4647 Seike M; Kondo T; Mori Y; Gemma A; Kudoh S; Sakamoto M; Yamada T; Hirohashi S Proteomic analysis of intestinal epithelial cells expressing stabilized beta-catenin	0	0
834	4	793 2003 CANCER RESEARCH 63(16):4773-4776 Siu IM; Lal A; Blankenship JR; Aldosari N; Riggins GJ c-myc promoter activation in medulloblastoma	0	0
835	2	794 2003 CANCER RESEARCH 63(16):4836-4841 Bertolino P; Tong WM; Herrera PL; Casse H; Zhang CX; Wang ZQ Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice	0	0
836	7	795 2003 CANCER RESEARCH 63(16):4990-4996 Yang WC; Bancroft L; Nicholas C; Lozonschi I; Augenlicht LH Targeted inactivation of p27(kip1) is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a western-style high-risk diet	0	0
837	6	796 2003 CANCER RESEARCH 63(19):6116-6120 Shimokawa T; Furukawa Y; Sakai M; Li MH; Miwa N; Lin YM; Nakamura Y Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex	0	0
838	3	797 2003 CANCER RESEARCH 63(19):6212-6220 Gatenby RA; Vincent TL An evolutionary model of carcinogenesis	0	0
839	3	798 2003 CANCER RESEARCH 63(19):6244-6251 Ayala G; Wang DG; Wulf G; Frolov A; Li R; Sowadski J; Wheeler TM; Lu KP; Bao L The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer	0	0
840	5	799 2003 CANCER RESEARCH 63(20):6626-6634 Chen DH; Xu WD; Bales E; Colmenares C; Conacci-Sorrell M; Ishii S; Stavnezer E; Campisi J; Fisher DE; Ben-Ze'ev A; Medrano EE SKI activates Wnt/beta-catenin signaling in human melanoma	0	0
841	9	800 2003 CANCER SCIENCE 94(1):103-111 Saegusa M; Hamano M; Kuwata T; Yoshida T; Hashimura M; Akino F; Watanabe J; Kuramoto H; Okayasu I Up-regulation and nuclear localization of beta-catenin in endometrial carcinoma in response to progestrone therapy	0	0
842	2	801 2003 CANCER SCIENCE 94(3):297-301 Hoshida Y; Hongyo T; Jia XS; He YJ; Hasui K; Dong ZM; Luo WJ; Ham MF; Nomura T; Aozasa K Analysis of p53, K-ras, c-kit, and beta-catenin gene mutations in sinonasal NK/T cell lymphoma in northeast district of China	0	0
843	7	802 2003 CANCER SCIENCE 94(6):515-518 Nagahata T; Shimada T; Harada A; Nagai H; Onda M; Yokoyama S; Shiba T; Jin EJ; Kawanami O; Emi M Amplification, up-regulation and over-expression of DVL-1, the human counterpart of the Drosophila disheveled gene, in primary breast cancers	0	0
844	1	803 2003 CANCER TREATMENT REVIEWS 29():49-57 Nalepa G; Harper JW Therapeutic anti-cancer targets upstream of the proteasome	0	0
845	6	804 2003 CARCINOGENESIS 24(1):17-24 Campbell PM; Szyf M Human DNA methyltransferase gene DNMT1 is regulated by the APC pathway	0	0
846	4	806 2003 CARCINOGENESIS 24(4):643-650 Husoy T; Cruciani V; Knutsen HK; Mikalsen SO; Olstorn HB; Alexander J Cells heterozygous for the Apc(Min) mutation have decreased gap junctional intercellular communication and connexin43 level, and reduced microtubule polymerization	0	0
847	7	807 2003 CARCINOGENESIS 24(6):1015-1019 Yamada Y; Mori H Pre-cancerous lesions for colorectal cancers in rodents: a new concept	0	0
848	8	809 2003 CELLULAR AND MOLECULAR LIFE SCIENCES 60(3):495-506 Janssen KP Murine models of colorectal cancer: studying the role of oncogenic K-ras	0	0
849	4	812 2003 CLINICAL & EXPERIMENTAL METASTASIS 20(6):525-529 Iwaya K; Ogawa H; Kuroda M; Izumi M; Ishida T; Mukai K Cytoplasmic and/or nuclear staining of beta-catenin is associated with lung metastasis	0	0
850	3	813 2003 CLINICAL CANCER RESEARCH 9(1):1-9 Koeffler HP Peroxisome proliferator-activated receptor gamma and cancers	0	0
851	13	816 2003 CLINICAL CANCER RESEARCH 9(6):2121-2132 Shiina H; Igawa M; Breault J; Ribeiro L; Pookot D; Urakami S; Terashima M; Deguchi M; Yamanaka M; Shirai M; Kaneuchi M; Kane CJ; Dahiya R The human T-cell factor-4 gene splicing isoforms, Wnt signal pathway, and apoptosis in renal cell carcinoma	0	0
852	9	817 2003 CLINICAL CANCER RESEARCH 9(8):3073-3079 Zhang B; Ougolkov A; Yamashita K; Takahashi Y; Mai M; Minamoto T beta-catenin and ras oncogenes detect most human colorectal cancer	0	0
853	10	818 2003 CLINICAL CANCER RESEARCH 9(9):3383-3388 Maelandsmo GM; Holm R; Nesland JM; Fodstad O; Florenes VA Reduced beta-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma	0	0
854	5	819 2003 CURRENT MOLECULAR MEDICINE 3(5):472-482 Harwood AJ Neurodevelopment and mood stabilizers	0	0
855	6	821 2003 CURRENT OPINION IN ONCOLOGY 15(1):44-49 Hermeking H Serial analysis of gene expression and cancer	0	0
856	3	823 2003 DEVELOPMENT GROWTH & DIFFERENTIATION 45(2):121-128 Miyawaki K; Yamamoto M; Saito K; Saito S; Kobayashi N; Matsuda S Nuclear localization of beta-catenin in vegetal pole cells during early embryogenesis of the starfish Asterina pectinifera	0	0
857	2	824 2003 DEVELOPMENTAL BIOLOGY 259(1):48-61 Stump RJW; Ang S; Chen YJ; von Bahr T; Lovicu FJ; Pinson K; de Iongh RU; Yamaguchi TP; Sassoon DA; McAvoy JW A role for Wnt/beta-catenin signaling in lens epithelial differentiation	0	0
858	4	825 2003 DEVELOPMENTAL BIOLOGY 261(1):165-182 Karsten SL; Kudo LC; Jackson R; Sabatti C; Kornblum HI; Geschwind DH Global analysis of gene expression in neural progenitors reveals specific cell-cycle, signaling, and metabolic networks	0	0
859	7	827 2003 DIAGNOSTIC MOLECULAR PATHOLOGY 12(1):44-49 Smyth P; Finn S; O'Leary J; Sheils O Real-time analysis of beta- and gamma-catenin mRNA expression in ret/PTC-1 activated and nonactivated thyroid tissues	0	0
860	6	829 2003 EMBO JOURNAL 22(12):3084-3094 Hocevar BA; Mou F; Rennolds JL; Morris SM; Cooper JA; Howe PH Regulation of the Wnt signaling pathway by disabled-2 (Dab2)	0	0
861	3	831 2003 ENDOCRINOLOGY 144(8):3618-3624 Fagman H; Grande M; Edsbagge J; Semb H; Nilsson M Expression of classical cadherins in thyroid development: Maintenance of an epithelial phenotype throughout organogenesis	0	0
862	14	833 2003 GASTROENTEROLOGY 124(1):202-216 Monga SPS; Monga HK; Tan XP; Mule K; Pediaditakis P; Michalopoulos GK beta-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and lineage specification	0	0
863	3	837 2003 GUT 52(5):759-766 Ho GT; Moodie FM; Satsangi J Multidrug resistance 1 gene (P-glycoprotein 170): an important determinant in gastrointestinal disease?	0	0
864	10	840 2003 HEPATOLOGY 38(1):178-186 Shibata T; Chuma M; Kokubu A; Sakamoto N; Hirohashi S EBP50, a beta-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma	0	0
865	6	842 2003 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 35(7):1034-1051 Visvader JE; Lindeman GJ Transcriptional regulators in mammary gland development and cancer	0	0
866	9	843 2003 INTERNATIONAL JOURNAL OF CANCER 103(4):435-439 Dietrich C; Faust D; Moskwa M; Kunz A; Bock KW; Oesch F TCDD-dependent downregulation of gamma-catenin in rat liver epithelial cells (WB-F344)	0	0
867	1	845 2003 INTERNATIONAL JOURNAL OF CANCER 104(1):44-53 Kohya N; Kitajima Y; Jiao W; Miyazaki K Effects of E-cadherin transfection on gene expression of a gallbladder carcinoma cell line: Repression of MTS1/S100A4 gene expression	0	0
868	4	846 2003 INTERNATIONAL JOURNAL OF CANCER 104(1):60-65 Fricke E; Keller G; Becker I; Rosivatz E; Schott C; Plaschke S; Rudelius M; Hermannstadter C; Busch R; Hofler H; Becker KF; Luber B Relationship between E-cadherin gene mutation and p53 gene mutation, p53 accumulation, Bcl-2 expression and Ki-67 staining in diffuse-type gastric carcinoma	0	0
869	20	847 2003 INTERNATIONAL JOURNAL OF CANCER 106(5):653-660 Pajari AM; Rajakangas J; Paivarinta E; Kosma VM; Rafter J; Mutanen M Promotion of intestinal tumor formation by inulin is associated with an accumulation of cytosolic beta-catenin in Min mice	0	0
870	9	848 2003 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 11(4):461-464 Miao JY; Kusafuka T; Kuroda S; Yoneda A; Zhou ZW; Okada A Mutation of beta-catenin and its protein accumulation in solid and cystic tumor of the pancreas associated with metastasis	0	0
871	9	849 2003 INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY 11(1):1-9 Nabais S; Machado JC; Lopes C; Seruca R; Carneiro F; Sobrinho-Simoes M Patterns of beta-catenin expression in gastric carcinoma: Clinicopathological relevance and mutation analysis	0	0
872	4	852 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(14):11937-11944 Kahler RA; Westendorf JJ Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter	0	0
873	12	853 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(15):13487-13495 Lyu J; Costantini F; Jho EH; Joo CK Ectopic expression of axin blocks neuronal differentiation of embryonic carcinoma P19 cells	0	0
874	13	854 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(16):14274-14283 Duchesne C; Charland S; Asselin C; Nahmias C; Rivard N Negative regulation of beta-catenin signaling by tyrosine phosphatase SHP-1 in intestinal epithelial cells	0	0
875	14	855 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(22):20259-20267 Ghiselli G; Coffee N; Munnery CE; Koratkar R; Siracusa LD The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway	0	0
876	13	856 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(33):30828-30834 Amir AL; Barua M; McKnight NC; Cheng ST; Yuan X; Balk SP A direct beta-catenin-independent interaction between androgen receptor and T cell factor 4	0	0
877	11	857 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(39):38029-38039 Wen YF; Caffrey TC; Wheelock MJ; Johnson KR; Hollingsworth MA Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin	0	0
878	9	861 2003 JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY 56(5):280-285 Pham K; Milovanovic T; Barr RJ; Truong T; Holcombe RF Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features	0	0
879	8	862 2003 JOURNAL OF IMMUNOLOGY 171(2):769-775 Ioannidis V; Kunz A; Tanamachi DM; Scarpellino L; Held W Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1	0	0
880	13	863 2003 JOURNAL OF INVESTIGATIVE DERMATOLOGY 121(2):242-251 Hu PQ; Berkowitz P; O'Keefe EJ; Rubenstein DS Keratinocyte adherens junctions initiate nuclear signaling by translocation of plakoglobin from the membrane to the nucleus	0	0
881	23	864 2003 JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA 8(2):145-158 Hatsell S; Rowlands T; Hiremath M; Cowin P beta-catenin and Tcfs in mammary development and cancer	0	0
882	3	865 2003 JOURNAL OF MEDICAL GENETICS 40(4):- Lipton L; Sieber OM; Thomas HJW; Hodgson SV; Tomlinson IPM; Woodford-Richens K Germline mutations in the TGF-beta and Wnt signalling pathways are a rare cause of the "multiple" adenoma phenotype	0	0
883	5	866 2003 JOURNAL OF MOLECULAR BIOLOGY 330(5):955-966 Reimer T; Weiwad M; Schierhorn A; Ruecknagel PK; Rahfeld JU; Bayer P; Fischer G Phosphorylation of the N-terminal domain regulates subcellular localization and DNA binding properties of the peptidyl-prolyl cis/trans isomerase hPar14	0	0
884	6	867 2003 JOURNAL OF NEUROSCIENCE RESEARCH 73(2):166-175 Uemura K; Kitagawa N; Kohno R; Kuzuya A; Kageyama T; Shibasaki H; Shimohama S Presenilin 1 mediates retinoic acid-induced differentiation of SH-SY5Y cells through facilitation of Wnt signaling	0	0
885	7	868 2003 JOURNAL OF NUTRITION 133(6):1943-1948 Rajakangas J; Basu S; Salminen I; Mutanen M Adenoma growth stimulation by the trans-10, cis-12 isomer of conjugated linoleic acid (CLA) is associated with changes in mucosal NF-kappa B and cyclin D1 protein levels in the Min mouse	0	0
886	1	870 2003 JOURNAL OF PATHOLOGY 200(1):59-64 Sawyer EJ; Poulsom R; Hunt FT; Jeffery R; Elia G; Ellis IO; Ellis P; Tomlinson IPM; Hanby AM Malignant phyllodes tumours show stromal overexpression of c-myc and c-kit	0	0
887	15	871 2003 JOURNAL OF PATHOLOGY 201(2):250-259 Prange W; Breuhahn K; Fischer F; Zilkens C; Pietsch T; Petmecky K; Eilers R; Dienes HP; Schirmacher P Beta-catenin accumulation in the progression of human hepatocarcinogenesis correlates with loss of E-cadherin and accumulation of p53, but not with expression of conventional WNT-1 target genes	0	0
888	5	872 2003 JOURNAL OF THE NATIONAL CANCER INSTITUTE 95(12):896-905 Kumagai T; O'Kelly J; Said JW; Koeffler HP Vitamin D-2 analog 19-nor-1,25-dihydroxyvitamin D-2: Antitumor activity against leukemia, myeloma, and colon cancer cells	0	0
889	3	873 2003 JOURNAL OF UROLOGY 170(5):1892-1896 Bryan RT; Nicholls JH; Harrison RF; Jankowski JA; Wallace DMA The role of beta-catenin signaling in the malignant potential of cystitis glandularis	0	0
890	3	874 2003 JOURNAL OF VETERINARY MEDICAL SCIENCE 65(8):853-856 Nakamuta N; Kobayashi S Expression of p63 in the testis of mouse embryos	0	0
891	2	876 2003 LEUKEMIA RESEARCH 27(4):359-361 Takeuchi S; Takeuchi N; Fermin AC; Taguchi H; Koeffler HP Frameshift mutations in caspase-5 and other target genes in leukemia and lymphoma cell lines having microsatellite instability	0	0
892	2	878 2003 LUNG CANCER 40(2):111-121 Sanchez-Cespedes M Dissecting the genetic alterations involved in lung carcinogenesis	0	0
893	2	879 2003 M S-MEDECINE SCIENCES 19(8-9):788-790 Hamelin R; Duval A beta-catenin and cell proliferation in normal and transformed intestinal cells	0	0
894	9	880 2003 MECHANISMS OF AGEING AND DEVELOPMENT 124(5):697-708 Lim IK Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats (vol 123, pg 1665, 2002)	0	0
895	6	881 2003 MECHANISMS OF DEVELOPMENT 120(2):157-165 Marygold SJ; Vincent JP Armadillo levels are reduced during mitosis in Drosophila	0	0
896	7	882 2003 MODERN PATHOLOGY 16(1):57-65 Venesio T; Balsamo A; Scordamaglia A; Bertolaso M; Arrigoni A; Sprujevnik T; Rossini FP; Risio M Germline APC mutation on the beta-catenin binding site is associated with a decreased apoptotic level in colorectal adenomas	0	0
897	13	883 2003 MOLECULAR AND CELLULAR BIOLOGY 23(11):3936-3950 Grueneberg DA; Pablo L; Hu KQ; August P; Weng ZG; Papkoff J A functional screen in human cells identifies UBF2 as an RNA polymerase II transcription factor that enhances the beta-catenin signaling pathway	0	0
898	3	884 2003 MOLECULAR AND CELLULAR BIOLOGY 23(18):6694-6701 Rao P; Kadesch T The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells	0	0
899	19	886 2003 MOLECULAR BIOLOGY OF THE CELL 14(7):2844-2860 Olmeda D; Castel S; Vilaro S; Cano A beta-catenin regulation during the cell cycle: Implications in G2/M and apoptosis	0	0
900	13	888 2003 MOLECULAR CANCER THERAPEUTICS 2(9):885-892 Rice PL; Kelloff J; Sullivan H; Driggers LJ; Beard KS; Kuwada S; Piazza G; Ahnen DJ Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells	0	0

#	Cited nodes	Nodes / Authors	GCS	LCS
901	9	889 2003 MOLECULAR CARCINOGENESIS 36(4):195-203 Blum CA; Tanaka T; Zhong XY; Li QJ; Dashwood WM; Pereira C; Xu MR; Dashwood RH Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: Mutational 'hotspots' and the relative expression of beta-catenin and c-jun	0	0
902	1	893 2003 NEOPLASIA 5(4):347-361 Nightingale J; Chaudhary KS; Abel PD; Stubbs AP; Romanska HM; Mitchell SE; Stamp GWH; Lalani EN Ligand activation of the androgen receptor downregulates E-cadherin-mediated cell adhesion and promotes apoptosis of prostatic cancer cells	0	0
903	12	894 2003 NUCLEIC ACIDS RESEARCH 31(9):2369-2380 Valenta T; Lukas J; Korinek V HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells	0	0
904	2	895 2003 NUCLEIC ACIDS RESEARCH 31(19):5789-5804 Gadal F; Bozic C; Pillot-Brochet C; Malinge S; Wagner S; Le Cam A; Buffat L; Crepin M; Iris F Integrated transcriptome analysis of the cellular mechanisms associated with Ha-ras-dependent malignant transformation of the human breast epithelial MCF7 cell line	0	0
905	3	897 2003 ONCOGENE 22(21):3297-3306 Wang WS; Chen PM; Hsiao HL; Ju SY; Su Y Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells	0	0
906	5	898 2003 ONCOGENE 22(24):3821-3826 Udtha M; Lee SJ; Alam R; Coombes K; Huff V Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors	0	0
907	11	899 2003 ONCOGENE 22(25):3901-3910 Yam JWP; Chan KW; Hsiao WLW Transcriptional regulation of the promoter of the rat frizzled related protein gene by CREB	0	0
908	5	900 2003 ONCOGENE 22(39):5978-5986 Usami N; Sekido Y; Maeda O; Yamamoto K; Minna JD; Hasegawa Y; Yoshioka H; Imaizumi M; Ueda Y; Takahashi M; Shimokata K beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion	0	0
909	12	901 2003 ONCOGENE 22(38):6013-6022 Fagman H; Larsson F; Arvidsson Y; Meuller J; Nordling M; Martinson T; Helmbrecht K; Brabant G; Nilsson M Nuclear accumulation of full-length and truncated adenomatous polyposis coli protein in tumor cells depends on proliferation	0	0
910	5	902 2003 ONCOGENE 22(42):6517-6523 Reiss K; Khalili K Viruses and cancer: lessons from the human polyomavirus, JCV	0	0
911	9	903 2003 ONCOLOGY REPORTS 10(2):455-461 Miyashita H; Mori S; Motegi K; Fukumoto M; Uchida T Pin1 is overexpressed in oral squamous cell carcinoma and its levels correlate with cyclin D1 overexpression	0	0
912	5	904 2003 ONCOLOGY REPORTS 10(5):1219-1223 Okino K; Nagai H; Hatta M; Nagahata T; Yoneyama K; Ohta Y; Jin EJ; Kawanami O; Araki T; Emi M Up-regulation and overproduction of DVL-1, the human counterpart of the Drosophila dishevelled gene, in cervical squamous cell carcinoma	0	0
913	6	906 2003 PATHOLOGE 24(1):49-60 Baldus SE Clinical, pathological and molecular prognostic factors in colorectal carcinomas	0	0
914	9	907 2003 PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES 2(8):825-834 Ehrhart JC; Gosselet FP; Culerrier RM; Sarasin A UVB-induced mutations in human key gatekeeper genes governing signalling pathways and consequences for skin tumourigenesis	0	0
915	9	909 2003 PIGMENT CELL RESEARCH 16(3):312-317 Larue L; Kumasaka M; Goding CR beta-catenin in the melanocyte lineage	0	0
916	9	915 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(18):10429-10434 Ohira T; Gemmill RM; Ferguson K; Kusy S; Roche J; Brambilla E; Zeng C; Baron A; Bemis L; Erickson P; Wilder E; Rustgi A; Kitajewski J; Gabrielson E; Bremnes R; Franklin W; Drabkin HA WNT7a induces E-cadherin in lung cancer cells	0	0
917	9	916 2003 THYROID 13(6):537-545 Meirmanov S; Nakashima M; Kondo H; Matsufuji R; Takamura N; Ishigaki K; Ito M; Prouglo Y; Yamashita S; Sekine I Correlation of cytoplasmic beta-catenin and cyclin D1 overexpression during thyroid carcinogenesis around Semipalatinsk nuclear test site	0	0
918	9	917 2003 TOXICOLOGY AND APPLIED PHARMACOLOGY 190(2):135-145 Anna CH; Iida M; Sills RC; Devereux TR Expression of potential beta-catenin targets, cyclin D1, c-Jun, c-Myc, E-cadherin, and EGFR in chemically induced hepatocellular neoplasms from B6C3F1 mice	0	0
919	12	919 2003 TRENDS IN CELL BIOLOGY 13(6):310-318 Balda MS; Matter K Epithelial cell adhesion and the regulation of gene expression	0	0

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