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Author(s): Cremona O; DeCamilli P
Title: Synaptic vesicle endocytosis
Source: CURRENT OPINION IN NEUROBIOLOGY 7 (3): 323-330
Date: 1997 JUN
Document Type: Journal : Article
Language: English
Comment:
Address: YALE UNIV,SCH MED,HOWARD HUGHES MED INST,NEW HAVEN,CT 06510.
UNIV TURIN,FAC MED 2,DEPT MED SCI,I-21100 NOVARA,ITALY. Reprint: Cremona, O, YALE UNIV,SCH MED,DEPT CELL BIOL,295 CONGRESS AVE,NEW
HAVEN,CT 06510. Abstract: Exocytosis of synaptic vesicles is followed rapidly by reinternalization and recycling of their membranes. Recent studies have confirmed the key role of clathrin-mediated endocytosis in synaptic vesicle reformation and have identified new proteins that participate in this process. In addition, growing evidence suggests that lipids, primarily phosphoinositides, play an important role in synaptic vesicle recycling.
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