HistCite - index: Papers by Bert Vogelstein

Wed Mar 23 11:59:48 2005

Papers by Bert Vogelstein

Nodes: 435, Authors: 1046, Journals: 95, Outer References: 6532, Words: 1171
Collection span: 1976 - 2005
View: Overview. Sorted by date.

# LCR NCR Nodes / Date / Journal / Authors LCS GCS
1 0 40 1 1976 [JUN 30] NEW ENGLAND JOURNAL OF MEDICINE 295(12):655-658
PRYSTOWSKY SD; VOGELSTEIN B; ETTINGER DS; MERZ WG; KAIZER H; et al.
INVASIVE ASPERGILLOSIS
0 105
2 0 0 2 1976 [JUN 30] PEDIATRIC RESEARCH 10(4):456-456
MOXON ER; VOGELSTEIN B; RILEY RL; MERZ WG; DOBSON ML; et al.
CUTANEOUS ASPERGILLUS INFECTION IN COMPROMISED HOSTS - CLINICAL AND EPIDEMIOLOGIC FEATURES
0 0
3 0 23 3 1976 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73(10):3671-3675
DINTZIS HM; DINTZIS RZ; VOGELSTEIN B
MOLECULAR DETERMINANTS OF IMMUNOGENICITY - IMMUNON MODEL OF IMMUNE-RESPONSE
2 157
4 0 9 4 1977 [JUN 30] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 75(4):1127-1132
VOGELSTEIN B; GILLESPIE D
RNA-DNA HYBRIDIZATION IN SOLUTION WITHOUT DNA RE-ANNEALING
4 26
5 0 26 5 1977 [JUN 30] CLINICAL PHARMACOLOGY & THERAPEUTICS 22(2):131-139
VOGELSTEIN B; KOWARSKI AA; LIETMAN PS
CONTINUOUS SAMPLING AS A PHARMACOKINETIC TOOL
0 19
6 0 36 6 1977 [JUN 30] JOURNAL OF PEDIATRICS 91(2):333-339
VOGELSTEIN B; AVINOAMKOWARSKI A; LIETMAN PS
PHARMACOKINETICS OF AMIKACIN IN CHILDREN
0 53
7 1 19 7 1979 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 76(2):615-619
VOGELSTEIN B; GILLESPIE D
PREPARATIVE AND ANALYTICAL PURIFICATION OF DNA FROM AGAROSE
7 1201
8 0 45 8 1980 [JUN 30] CELL 19(2):527-536
PARDOLL DM; VOGELSTEIN B; COFFEY DS
FIXED SITE OF DNA-REPLICATION IN EUKARYOTIC CELLS
9 581
9 1 44 9 1980 [JUN 30] CELL 22(1):79-85
VOGELSTEIN B; PARDOLL DM; COFFEY DS
SUPERCOILED LOOPS AND EUKARYOTIC DNA-REPLICATION
11 511
10 2 23 10 1980 [JUN 30] EXPERIMENTAL CELL RESEARCH 128(2):466-470
PARDOLL DM; VOGELSTEIN B
SEQUENCE-ANALYSIS OF NUCLEAR MATRIX ASSOCIATED DNA FROM RAT-LIVER
7 78
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
11 0 24 11 1980 [JUN 30] FEBS LETTERS 109(2):233-238
NELKIN B; NICHOLS C; VOGELSTEIN B
PROTEIN FACTOR(S) FROM MITOTIC CHO CELLS INDUCE MEIOTIC MATURATION IN XENOPUS-LAEVIS OOCYTES
1 91
12 2 32 12 1980 [JUN 30] GENE 11(1-2):89-96
NELKIN B; STRAYER D; VOGELSTEIN B
DIVERGENCE OF PRIMATE RIBOSOMAL-RNA GENES AS ASSAYED BY RESTRICTION ENZYME ANALYSIS
0 10
13 3 55 13 1980 [JUN 30] NUCLEIC ACIDS RESEARCH 8(23):5623-5633
NELKIN BD; PARDOLL DM; VOGELSTEIN B
LOCALIZATION OF SV40-GENES WITHIN SUPERCOILED LOOP DOMAINS
7 101
14 1 18 14 1981 [JUN 30] EXPERIMENTAL CELL RESEARCH 133(2):445-449
ROBINSON SI; NELKIN B; KAUFMANN S; VOGELSTEIN B
INCREASED PHOSPHORYLATION RATE OF INTERMEDIATE FILAMENTS DURING MITOTIC ARREST
0 21
15 2 54 15 1981 [JUN 30] NUCLEIC ACIDS RESEARCH 9(2):349-363
HUNT BF; VOGELSTEIN B
ASSOCIATION OF NEWLY REPLICATED DNA WITH THE NUCLEAR MATRIX OF PHYSARUM-POLYCEPHALUM
4 76
16 5 59 16 1982 [JUN 30] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 105(3):1224-1232
VOGELSTEIN B; HUNT BF
A SUBSET OF SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE ANTIGENS IS A COMPONENT OF THE NUCLEAR MATRIX
0 44
17 5 75 17 1982 [JUN 30] CELL 28(1):99-106
ROBINSON SI; NELKIN BD; VOGELSTEIN B
THE OVALBUMIN GENE IS ASSOCIATED WITH THE NUCLEAR MATRIX OF CHICKEN OVIDUCT CELLS
7 337
18 0 0 18 1982 [JUN 30] FEDERATION PROCEEDINGS 41(4):1461-1461
NELKIN BD; ROBINSON SI; SMALL D; VOGELSTEIN B
THE NUCLEAR MATRIX, SUPERCOILED LOOPS AND GENE-EXPRESSION
0 0
19 0 0 19 1982 [JUN 30] JOURNAL OF CELL BIOLOGY 95(2):A76-A76
SMALL D; NELKIN B; GILMOUR D; LIS J; VOGELSTEIN B
ASSOCIATION OF TRANSCRIBED GENES WITH THE NUCLEAR MATRIX OF DROSOPHILA CELLS BEFORE AND DURING HEAT-SHOCK
0 4
20 0 0 20 1982 [JUN 30] JOURNAL OF CELL BIOLOGY 95(2):A224-A224
FEINBERG AP; VOGELSTEIN B
HYPOMETHYLATION OF SPECIFIC GENES IN SOME HUMAN CANCERS
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
21 1 22 21 1982 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(2):395-399
VOGELSTEIN B; DINTZIS RZ; DINTZIS HM
SPECIFIC CELLULAR-STIMULATION IN THE PRIMARY IMMUNE-RESPONSE - A QUANTIZED MODEL
2 39
22 2 37 22 1982 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(3):884-888
DINTZIS RZ; VOGELSTEIN B; DINTZIS HM
SPECIFIC CELLULAR-STIMULATION IN THE PRIMARY IMMUNE-RESPONSE - EXPERIMENTAL TEST OF A QUANTIZED MODEL
0 39
23 4 40 23 1982 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(19):5911-5915
SMALL D; NELKIN B; VOGELSTEIN B
NONRANDOM DISTRIBUTION OF REPEATED DNA-SEQUENCES WITH RESPECT TO SUPERCOILED LOOPS AND THE NUCLEAR MATRIX
1 66
24 1 1 24 1982 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(23):7604-7604
VOGELSTEIN B
CORRECTION
0 0
25 0 0 25 1982 [JUN 30] RADIATION RESEARCH 91(2):403-403
VOGELSTEIN B
SUPERCOILED LOOPS AND DNA ORGANIZATION
0 0
26 6 85 26 1982 [JUN 30] UCLA SYMPOSIA ON MOLECULAR AND CELLULAR BIOLOGY 26:105-119
VOGELSTEIN B; NELKIN B; PARDOLL D; ROBINSON S; SMALL D
SUPERCOILED LOOPS AND TRANSCRIBING GENES
0 2
27 0 33 27 1983 [JUN 30] ANALYTICAL BIOCHEMISTRY 132(1):6-13
FEINBERG AP; VOGELSTEIN B
A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY
21 20884
28 1 46 28 1983 [JUN 30] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 111(1):47-54
FEINBERG AP; VOGELSTEIN B
HYPOMETHYLATION OF RAS ONCOGENES IN PRIMARY HUMAN CANCERS
4 229
29 0 57 29 1983 [JUN 30] NATURE 301(5895):89-92
FEINBERG AP; VOGELSTEIN B
HYPOMETHYLATION DISTINGUISHES GENES OF SOME HUMAN CANCERS FROM THEIR NORMAL COUNTERPARTS
7 486
30 5 40 30 1983 [JUN 30] NUCLEIC ACIDS RESEARCH 11(15):5113-5130
ROBINSON SI; SMALL D; IDZERDA R; MCKNIGHT GS; VOGELSTEIN B
THE ASSOCIATION OF TRANSCRIPTIONALLY ACTIVE GENES WITH THE NUCLEAR MATRIX OF THE CHICKEN OVIDUCT
3 133
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
31 2 47 31 1983 [JUN 30] SCIENCE 220(4602):1175-1177
FEINBERG AP; VOGELSTEIN B; DROLLER MJ; BAYLIN SB; NELKIN BD
MUTATION AFFECTING THE 12TH AMINO-ACID OF THE C-HA-RAS ONCOGENE PRODUCT OCCURS INFREQUENTLY IN HUMAN CANCER
3 131
32 0 0 32 1984 [JUN 30] JOURNAL OF CELL BIOLOGY 99(4):A128-A128
HALLIGAN BD; SMALL D; VOGELSTEIN B; HSIEH TS; LIU LF
LOCALIZATION OF TYPE-II DNA TOPOISOMERASE IN NUCLEAR MATRIX
0 15
33 1 40 33 1984 [JUN 30] NATURE 309(5964):176-178
FEARON ER; VOGELSTEIN B; FEINBERG AP
SOMATIC DELETION AND DUPLICATION OF GENES ON CHROMOSOME-11 IN WILMS-TUMORS
6 447
34 2 22 34 1985 [JUN 30] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 130(1):118-126
GOELZ SE; HAMILTON SR; VOGELSTEIN B
PURIFICATION OF DNA FROM FORMALDEHYDE FIXED AND PARAFFIN EMBEDDED HUMAN-TISSUE
31 697
35 7 33 35 1985 [JUN 30] BIOESSAYS 2(2):52-54
ZEHNBAUER BA; VOGELSTEIN B
SUPERCOILED LOOPS AND THE ORGANIZATION OF REPLICATION AND TRANSCRIPTION IN EUKARYOTES
1 59
36 3 36 36 1985 [JUN 30] NATURE 318(6044):377-380
FEARON ER; FEINBERG AP; HAMILTON SH; VOGELSTEIN B
LOSS OF GENES ON THE SHORT ARM OF CHROMOSOME-11 IN BLADDER-CANCER
9 371
37 5 59 37 1985 [JUN 30] NUCLEIC ACIDS RESEARCH 13(7):2413-2431
SMALL D; NELKIN B; VOGELSTEIN B
THE ASSOCIATION OF TRANSCRIBED GENES WITH THE NUCLEAR MATRIX OF DROSOPHILA CELLS DURING HEAT-SHOCK
1 96
38 7 34 38 1985 [JUN 30] NUCLEIC ACIDS RESEARCH 13(21):7703-7713
SMALL D; VOGELSTEIN B
THE ANATOMY OF SUPERCOILED LOOPS IN THE DROSOPHILA-7F LOCUS
0 15
39 0 0 39 1985 [JUN 30] PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 26(MAR):64-64
TRENT J; MELTZER P; ROSENBLUM M; HARSH G; KINZLER K; et al.
EVIDENCE FOR REARRANGEMENT AND AMPLIFICATION OF THE C-MYC CELLULAR ONCOGENE IN A HUMAN GLIOBLASTOMA
0 4
40 1 42 40 1985 [JUN 30] SCIENCE 227(4687):642-645
VOGELSTEIN B; FEARON ER; HAMILTON SR; FEINBERG AP
USE OF RESTRICTION FRAGMENT LENGTH POLYMORPHISMS TO DETERMINE THE CLONAL ORIGIN OF HUMAN-TUMORS
7 339
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
41 3 54 41 1985 [JUN 30] SCIENCE 228(4696):187-190
GOELZ SE; VOGELSTEIN B; HAMILTON SR; FEINBERG AP
HYPOMETHYLATION OF DNA FROM BENIGN AND MALIGNANT HUMAN-COLON NEOPLASMS
8 367
42 0 18 43 1986 JAN 1 CANCER GENETICS AND CYTOGENETICS 19(1-2):93-99
MELTZER P; KINZLER K; VOGELSTEIN B; TRENT JM
GENE AMPLIFICATION IN CANCER - A MOLECULAR CYTOGENETIC APPROACH
0 15
43 0 25 48 1986 JAN [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(2):470-473
TRENT J; MELTZER P; ROSENBLUM M; HARSH G; KINZLER K; et al.
EVIDENCE FOR REARRANGEMENT, AMPLIFICATION, AND EXPRESSION OF C-MYC IN A HUMAN GLIOBLASTOMA
7 134
44 2 41 49 1986 FEB [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(4):1031-1035
KINZLER KW; ZEHNBAUER BA; BRODEUR GM; SEEGER RC; TRENT JM; et al.
AMPLIFICATION UNITS CONTAINING HUMAN N-MYC AND C-MYC GENES
5 80
45 1 13 42 1986 MAR [15] BLOOD 67(3):835-838
ZEHNBAUER BA; PARDOLL DM; BURKE PJ; GRAHAM ML; VOGELSTEIN B
IMMUNOGLOBULIN GENE REARRANGEMENTS IN REMISSION BONE-MARROW SPECIMENS FROM PATIENTS WITH ACUTE LYMPHOBLASTIC-LEUKEMIA
0 92
46 0 0 44 1986 APR [15] CLINICAL RESEARCH 34(2):A689-A689
BAYLIN SB; FEARON ER; VOGELSTEIN B; DEBUSTROS A; SHARKIS SJ; et al.
HYPERMETHYLATION OF THE CALCITONIN GENE - A PROPERTY OF HUMAN SMALL-CELL LUNG-CANCER AND LYMPHO-HEMATOPOIETIC MALIGNANCIES
0 1
47 0 0 45 1986 [JUN 30] JOURNAL OF NEURO-ONCOLOGY 4(1):92-92
BIGNER SH; MARK J; KINZLER KW; VOGELSTEIN B; SCHOLD SC; et al.
CHROMOSOMES AND GENE AMPLIFICATION IN MALIGNANT HUMAN GLIOMAS
0 0
48 3 54 46 1986 JUL 3 NEW ENGLAND JOURNAL OF MEDICINE 315(1):15-24
FEARON ER; BURKE PJ; SCHIFFER CA; ZEHNBAUER BA; VOGELSTEIN B
DIFFERENTIATION OF LEUKEMIA-CELLS TO POLYMORPHONUCLEAR LEUKOCYTES IN PATIENTS WITH ACUTE NONLYMPHOCYTIC LEUKEMIA
3 300
49 3 50 50 1986 JUL 25 SCIENCE 233(4762):461-464
WONG AJ; RUPPERT JM; EGGLESTON J; HAMILTON SR; BAYLIN SB; et al.
GENE AMPLIFICATION OF C-MYC AND N-MYC IN SMALL CELL-CARCINOMA OF THE LUNG
7 255
50 0 2 47 1986 DEC 4 NEW ENGLAND JOURNAL OF MEDICINE 315(23):1488-1488
FEARON ER; BURKE PJ; ZEHNBAUER BA; VOGELSTEIN B; SCHIFFER CA
DIFFERENTIATION OF BLAST CELLS IN ACUTE NONLYMPHOCYTIC LEUKEMIA - REPLY
0 2
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
51 2 16 51 1987 JAN [15] ANALYTICAL BIOCHEMISTRY 160(1):115-118
VOGELSTEIN B
RAPID PURIFICATION OF DNA FROM AGAROSE GELS BY CENTRIFUGATION THROUGH A DISPOSABLE PLASTIC COLUMN
8 25
52 3 32 62 1987 FEB 19 NEW ENGLAND JOURNAL OF MEDICINE 316(8):427-431
FEARON ER; WINKELSTEIN JA; CIVIN CI; PARDOLL DM; VOGELSTEIN B
CARRIER DETECTION IN X-LINKED AGAMMAGLOBULINEMIA BY ANALYSIS OF X-CHROMOSOME INACTIVATION
2 136
53 0 0 58 1987 MAR 1 FEDERATION PROCEEDINGS 46(3):973-973
NELKIN BD; FEARON ER; VOGELSTEIN B; DEBUSTROS A; PRZEPIORKA D; et al.
INCREASED CALCITONIN GENE DNA METHYLATION IN HUMAN LYMPHOID AND MYELOID MALIGNANCIES
0 0
54 0 0 59 1987 MAR [15] IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY 23(3):A29-A29
VOGELSTEIN B; FEARON ER
CLONAL ANALYSIS OF HUMAN-CELLS USING RECOMBINANT-DNA TECHNIQUES
0 0
55 0 0 64 1987 MAR [15] PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 28:23-23
HUMPHREY PA; WONG AJ; FRIEDMAN HS; WERNER MH; VOGELSTEIN B; et al.
AMPLIFICATION AND EXPRESSION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR (EGFR) GENE IN HUMAN GLIOMA (HGL) XENOGRAFTS
1 2
56 3 43 66 1987 APR 3 SCIENCE 236(4797):70-73
KINZLER KW; BIGNER SH; BIGNER DD; TRENT JM; LAW ML; et al.
IDENTIFICATION OF AN AMPLIFIED, HIGHLY EXPRESSED GENE IN A HUMAN GLIOMA
15 311
57 0 0 63 1987 APR [15] PEDIATRIC RESEARCH 21(4):A313-A313
KOHN DB; FEARON ER; WINKLESTEIN JA; VOGELSTEIN B; BLAESE RM
WISKOTT-ALDRICH SYNDROME (WAS) CARRIER DETECTION BY X-CHROMOSOME INACTIVATION ANALYSIS
0 8
58 0 0 60 1987 MAY [15] JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 46(3):373-373
BIGNER SH; BURGER PC; WONG AJ; KINZLER KK; HAMILTON SR; et al.
MORPHOLOGICAL-CHARACTERISTICS OF MALIGNANT HUMAN GLIOMAS (MHG) WITH GENE AMPLIFICATION
0 0
59 2 30 61 1987 MAY 28 NATURE 327(6120):293-297
BOS JL; FEARON ER; HAMILTON SR; VERLAANDEVRIES M; VANBOOM JH; et al.
PREVALENCE OF RAS GENE-MUTATIONS IN HUMAN COLORECTAL CANCERS
20 1254
60 0 0 57 1987 [JUN 30] CYTOGENETICS AND CELL GENETICS 46(1-4):639-639
KINZLER KW; BIGNER SH; BIGNER DD; TRENT JM; LAW ML; et al.
IDENTIFICATION OF AN AMPLIFIED, HIGHLY EXPRESSED GENE IN A HUMAN GLIOMA
0 2
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
61 0 0 68 1987 [JUN 30] SEMINARS IN SURGICAL ONCOLOGY 3(3):149-151
FEINBERG AP; VOGELSTEIN B
ALTERATIONS IN DNA METHYLATION IN HUMAN-COLON NEOPLASIA
0 10
62 5 26 52 1987 AUG [15] BLOOD 70(2):412-417
BAYLIN SB; FEARON ER; VOGELSTEIN B; DEBUSTROS A; SHARKIS SJ; et al.
HYPERMETHYLATION OF THE 5' REGION OF THE CALCITONIN GENE IS A PROPERTY OF HUMAN LYMPHOID AND ACUTE MYELOID MALIGNANCIES
0 83
63 0 0 53 1987 SEP [15] CANCER GENETICS AND CYTOGENETICS 28(1):32-32
BIGNER SH; WONG AJ; MARK J; KINZLER KW; VOGELSTEIN B; et al.
CHROMOSOMES AND GENE AMPLIFICATION IN MALIGNANT HUMAN GLIOMAS (MHG)
0 1
64 0 1 54 1987 SEP [15] CANCER GENETICS AND CYTOGENETICS 28(1):32-32
MELTZER P; COCCIA M; KINZLER K; VOGELSTEIN B; TRENT J
RENATURATION GEL ANALYSIS OF AMPLIFIED DNA-SEQUENCES
0 0
65 9 54 56 1987 SEP 15 CANCER RESEARCH 47(18):4806-4813
VOGELSTEIN B; FEARON ER; HAMILTON SR; PREISINGER AC; WILLARD HF; et al.
CLONAL ANALYSIS USING RECOMBINANT-DNA PROBES FROM THE X-CHROMOSOME
14 416
66 6 65 67 1987 OCT 9 SCIENCE 238(4824):193-197
FEARON ER; HAMILTON SR; VOGELSTEIN B
CLONAL ANALYSIS OF HUMAN COLORECTAL TUMORS
11 476
67 4 39 65 1987 OCT [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 84(19):6899-6903
WONG AJ; BIGNER SH; BIGNER DD; KINZLER KW; HAMILTON SR; et al.
INCREASED EXPRESSION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR GENE IN MALIGNANT GLIOMAS IS INVARIABLY ASSOCIATED WITH GENE AMPLIFICATION
12 462
68 3 20 55 1987 NOV [15] CANCER GENETICS AND CYTOGENETICS 29(1):165-170
BIGNER SH; WONG AJ; MARK J; MUHLBAIER LH; KINZLER KW; et al.
RELATIONSHIP BETWEEN GENE AMPLIFICATION AND CHROMOSOMAL DEVIATIONS IN MALIGNANT HUMAN GLIOMAS
3 88
69 0 0 75 1988 JAN [15] LABORATORY INVESTIGATION 58(1):A47-A47
KERN S; BOS JL; FEARON ER; VOGELSTEIN B; HAMILTON SR
THE RELATIONSHIP BETWEEN RAS GENE-MUTATIONS AND THE ADENOMA-CARCINOMA SEQUENCE IN THE COLORECTUM
0 0
70 0 0 76 1988 JAN [15] MODERN PATHOLOGY 1(1):A47-A47
KERN S; BOS JL; FEARON ER; VOGELSTEIN B; HAMILTON SR
THE RELATIONSHIP BETWEEN RAS GENE-MUTATIONS AND THE ADENOMA-CARCINOMA SEQUENCE IN THE COLORECTUM
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
71 6 40 77 1988 FEB [15] MOLECULAR AND CELLULAR BIOLOGY 8(2):522-530
ZEHNBAUER BA; SMALL D; BRODEUR GM; SEEGER R; VOGELSTEIN B
CHARACTERIZATION OF N-MYC AMPLIFICATION UNITS IN HUMAN NEURO-BLASTOMA CELLS
1 46
72 2 7 74 1988 MAR [15] JOURNAL OF PATHOLOGY 154(3):205-206
HAMILTON SR; VOGELSTEIN B
POINT MUTATIONS IN HUMAN NEOPLASIA
0 8
73 0 0 81 1988 MAR [15] PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 29:78-78
HUMPHREY PA; WONG AJ; VOGELSTEIN B; FRIEDMAN HS; BIGNER DD; et al.
LOSS OF EPIDERMAL GROWTH-FACTOR RECEPTOR GENE AMPLIFICATION AS MALIGNANT HUMAN GLIOMAS ESTABLISH IN CULTURE
1 4
74 0 0 82 1988 MAR [15] PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 29:393-393
SCHACKERT H; ITAYA T; HUNT B; FEARON E; VOGELSTEIN B; et al.
SYSTEMIC IMMUNOPROTECTION AFFORDED BY TUMOR-CELLS TRANSFECTED WITH A FOREIGN (VIRAL) GENE
0 0
75 3 29 79 1988 MAR 24 NATURE 332(6162):371-374
KINZLER KW; RUPPERT JM; BIGNER SH; VOGELSTEIN B
THE GLI GENE IS A MEMBER OF THE KRUPPEL FAMILY OF ZINC FINGER PROTEINS
9 236
76 3 35 70 1988 APR 15 CANCER RESEARCH 48(8):2231-2238
HUMPHREY PA; WONG AJ; VOGELSTEIN B; FRIEDMAN HS; WERNER MH; et al.
AMPLIFICATION AND EXPRESSION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR GENE IN HUMAN GLIOMA XENOGRAFTS
6 143
77 4 21 73 1988 MAY [15] JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 47(3):191-205
BIGNER SH; BURGER PC; WONG AJ; WERNER MH; HAMILTON SR; et al.
GENE AMPLIFICATION IN MALIGNANT HUMAN GLIOMAS - CLINICAL AND HISTOPATHOLOGIC ASPECTS
0 168
78 2 31 71 1988 JUN 1 CANCER RESEARCH 48(11):2975-2980
FEARON ER; ITAYA T; HUNT B; VOGELSTEIN B; FROST P
INDUCTION IN A MURINE TUMOR OF IMMUNOGENIC TUMOR VARIANTS BY TRANSFECTION WITH A FOREIGN GENE
2 101
79 7 35 72 1988 [JUN 30] ISI ATLAS OF SCIENCE-BIOCHEMISTRY 1(4):333-336
BIGNER SH; VOGELSTEIN B; BIGNER DD
CHROMOSOMAL-ABNORMALITIES AND GENE AMPLIFICATION IN MALIGNANT GLIOMAS
0 10
80 5 64 78 1988 AUG [15] MOLECULAR AND CELLULAR BIOLOGY 8(8):3104-3113
RUPPERT JM; KINZLER KW; WONG AJ; BIGNER SH; KAO FT; et al.
THE GLI-KRUPPEL FAMILY OF HUMAN GENES
5 200
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
81 7 55 80 1988 SEP 1 NEW ENGLAND JOURNAL OF MEDICINE 319(9):525-532
VOGELSTEIN B; FEARON ER; HAMILTON SR; KERN SE; PREISINGER AC; et al.
GENETIC ALTERATIONS DURING COLORECTAL-TUMOR DEVELOPMENT
49 3189
82 3 28 69 1988 NOV [15] BLOOD 72(5):1735-1739
FEARON ER; KOHN DB; WINKELSTEIN JA; VOGELSTEIN B; BLAESE RM
CARRIER DETECTION IN THE WISKOTT ALDRICH SYNDROME
0 82
83 7 89 91 1989 APR 14 SCIENCE 244(4901):207-211
VOGELSTEIN B; FEARON ER; KERN SE; HAMILTON SR; PREISINGER AC; et al.
ALLELOTYPE OF COLORECTAL CARCINOMAS
26 1097
84 7 69 92 1989 APR 14 SCIENCE 244(4901):217-221
BAKER SJ; FEARON ER; NIGRO JM; HAMILTON SR; PREISINGER AC; et al.
CHROMOSOME-17 DELETIONS AND P53 GENE-MUTATIONS IN COLORECTAL CARCINOMAS
38 1472
85 2 21 85 1989 APR [15] HUMAN GENETICS 82(1):1-2
ARHEDEN K; RONNE M; MANDAHL N; HEIM S; KINZLER KW; et al.
INSITU HYBRIDIZATION LOCALIZES THE HUMAN PUTATIVE ONCOGENE GLI TO CHROMOSOME SUBBANDS 12Q13.3-14.1
5 35
86 1 19 86 1989 MAY 15 INTERNATIONAL JOURNAL OF CANCER 43(5):823-827
SCHACKERT HK; ITAYA T; SCHACKERT G; FEARON E; VOGELSTEIN B; et al.
SYSTEMIC IMMUNITY AGAINST A MURINE COLON-TUMOR (CT-26) PRODUCED BY IMMUNIZATION WITH SYNGENEIC CELLS EXPRESSING A TRANSFECTED VIRAL GENE-PRODUCT
0 15
87 1 17 90 1989 MAY 25 NUCLEIC ACIDS RESEARCH 17(10):3645-3653
KINZLER KW; VOGELSTEIN B
WHOLE GENOME PCR - APPLICATION TO THE IDENTIFICATION OF SEQUENCES BOUND BY GENE REGULATORY PROTEINS
12 152
88 4 40 87 1989 JUN 2 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 261(21):3099-3103
KERN SE; FEARON ER; TERSMETTE KWF; ENTERLINE JP; LEPPERT M; et al.
ALLELIC LOSS IN COLORECTAL-CARCINOMA
7 322
89 0 0 83 1989 AUG [15] CANCER AND METASTASIS REVIEWS 8(2):166-166
VOGELSTEIN B
GENETIC ALTERATIONS UNDERLYING COLORECTAL TUMOR-DEVELOPMENT
0 0
90 0 0 84 1989 SEP [15] CANCER GENETICS AND CYTOGENETICS 41(2):226-226
BIGNER SH; VOGELSTEIN B; MARK J; BIGNER DD
CYTOGENETICS AND GENE AMPLIFICATION IN MALIGNANT HUMAN-BRAIN TUMORS
0 3
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
91 0 0 88 1989 SEP 15 MUNCHENER MEDIZINISCHE WOCHENSCHRIFT 131(37):38-&
VOGELSTEIN B
MECHANISMS OF METASTASIS
0 0
92 2 28 89 1989 DEC 7 NATURE 342(6250):705-708
NIGRO JM; BAKER SJ; PREISINGER AC; JESSUP JM; HOSTETTER R; et al.
MUTATIONS IN THE P53 GENE OCCUR IN DIVERSE HUMAN-TUMOR TYPES
36 2358
93 6 82 110 1990 JAN 5 SCIENCE 247(4938):49-56
FEARON ER; CHO KR; NIGRO JM; KERN SE; SIMONS JW; et al.
IDENTIFICATION OF A CHROMOSOME-18Q GENE THAT IS ALTERED IN COLORECTAL CANCERS
27 1419
94 0 44 98 1990 FEB 9 CELL 60(3):397-403
FEARON ER; PARDOLL DM; ITAYA T; GOLUMBEK P; LEVITSKY HI; et al.
INTERLEUKIN-2 PRODUCTION BY TUMOR-CELLS BYPASSES T-HELPER FUNCTION IN THE GENERATION OF AN ANTITUMOR RESPONSE
1 937
95 7 30 103 1990 FEB [15] MOLECULAR AND CELLULAR BIOLOGY 10(2):634-642
KINZLER KW; VOGELSTEIN B
THE GLI GENE ENCODES A NUCLEAR-PROTEIN WHICH BINDS SPECIFIC SEQUENCES IN THE HUMAN GENOME
4 178
96 7 28 94 1990 APR 15 CANCER RESEARCH 50(8):2347-2350
BIGNER SH; FRIEDMAN HS; VOGELSTEIN B; OAKES WJ; BIGNER DD
AMPLIFICATION OF THE C-MYC GENE IN HUMAN MEDULLOBLASTOMA CELL-LINES AND XENOGRAFTS
1 113
97 2 2 107 1990 MAY 11 NUCLEIC ACIDS RESEARCH 18(9):2834-2834
KINZLER KW; VOGELSTEIN B
ECORI POLYMORPHISM WITHIN THE GLI GENE (CHROMOSOME 12Q13.3-14.1)
0 6
98 0 0 102 1990 MAY [15] JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 49(3):320-320
FULLER GN; BURGER PC; SCHOLD SC; PREISINGER A; WONG AJ; et al.
GENE AMPLIFICATION IN HUMAN GLIOMAS
0 7
99 9 77 99 1990 JUN 1 CELL 61(5):759-767
FEARON ER; VOGELSTEIN B
A GENETIC MODEL FOR COLORECTAL TUMORIGENESIS
34 4851
100 2 28 108 1990 JUN [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(11):4207-4211
HUMPHREY PA; WONG AJ; VOGELSTEIN B; ZALUTSKY MR; FULLER GN; et al.
ANTISYNTHETIC PEPTIDE ANTIBODY REACTING AT THE FUSION JUNCTION OF DELETION MUTANT EPIDERMAL GROWTH-FACTOR RECEPTORS IN HUMAN GLIOBLASTOMA
1 164
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
101 2 19 101 1990 JUL [15] GENES CHROMOSOMES & CANCER 2(2):159-162
VOGELSTEIN B; CIVIN CI; PREISINGER AC; KRISCHER JP; STEUBER P; et al.
RAS GENE-MUTATIONS IN CHILDHOOD ACUTE MYELOID-LEUKEMIA - A PEDIATRIC ONCOLOGY GROUP-STUDY
0 22
102 5 43 111 1990 AUG 24 SCIENCE 249(4971):912-915
BAKER SJ; MARKOWITZ S; FEARON ER; WILLSON JKV; VOGELSTEIN B
SUPPRESSION OF HUMAN COLORECTAL-CARCINOMA CELL-GROWTH BY WILD-TYPE-P53
30 1527
103 0 0 93 1990 SEP [15] BRITISH JOURNAL OF CANCER 62(3):475-475
VOGELSTEIN B
GENETIC ALTERATIONS UNDERLYING COLORECTAL TUMORIGENESIS
0 0
104 6 52 104 1990 OCT [15] MOLECULAR AND CELLULAR BIOLOGY 10(10):5408-5415
RUPPERT JM; VOGELSTEIN B; ARHEDEN K; KINZLER KW
GL13 ENCODES A 190-KILODALTON PROTEIN WITH MULTIPLE REGIONS OF GLI SIMILARITY
1 122
105 3 60 105 1990 NOV [15] MOLECULAR AND CELLULAR BIOLOGY 10(11):5772-5781
DILLER L; KASSEL J; NELSON CE; GRYKA MA; LITWAK G; et al.
P53 FUNCTIONS AS A CELL-CYCLE CONTROL PROTEIN IN OSTEOSARCOMAS
11 757
106 8 62 95 1990 DEC 1 CANCER RESEARCH 50(23):7717-7722
BAKER SJ; PREISINGER AC; JESSUP JM; PARASKEVA C; MARKOWITZ S; et al.
P53 GENE-MUTATIONS OCCUR IN COMBINATION WITH 17P ALLELIC DELETIONS AS LATE EVENTS IN COLORECTAL TUMORIGENESIS
29 889
107 4 43 96 1990 DEC 15 CANCER RESEARCH 50(24):7902-7907
PAULIEN S; TURCCAREL C; DALCIN P; JANISAIT S; SREEKANTAIAH C; et al.
MYXOID LIPOSARCOMA WITH T(12-16) (Q13-P11) CONTAINS SITE-SPECIFIC DIFFERENCES IN METHYLATION PATTERNS SURROUNDING A ZINC-FINGER GENE MAPPED TO THE BREAKPOINT REGION ON CHROMOSOME-12
0 24
108 3 29 97 1990 DEC 15 CANCER RESEARCH 50(24):8017-8022
BIGNER SH; HUMPHREY PA; WONG AJ; VOGELSTEIN B; MARK J; et al.
CHARACTERIZATION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR IN HUMAN GLIOMA CELL-LINES AND XENOGRAFTS
0 137
109 4 59 100 1990 DEC [15] CELL GROWTH & DIFFERENTIATION 1(12):571-580
HINDS PW; FINLAY CA; QUARTIN RS; BAKER SJ; FEARON ER; et al.
MUTANT P53 DNA CLONES FROM HUMAN COLON CARCINOMAS COOPERATE WITH RAS IN TRANSFORMING PRIMARY RAT-CELLS - A COMPARISON OF THE HOT-SPOT MUTANT PHENOTYPES
4 421
110 3 48 109 1990 DEC [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(23):9275-9279
FRIEDMAN PN; KERN SE; VOGELSTEIN B; PRIVES C
WILD-TYPE, BUT NOT MUTANT, HUMAN P53 PROTEINS INHIBIT THE REPLICATION ACTIVITIES OF SIMIAN VIRUS-40 LARGE TUMOR-ANTIGEN
5 111
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
111 0 11 106 1990 DEC 20 NATURE 348(6303):681-682
VOGELSTEIN B
CANCER - A DEADLY INHERITANCE
9 282
112 0 0 124 1991 JAN [15] LABORATORY INVESTIGATION 64(1):A39-A39
OFFERHAUS GJA; CORNELISSE CJ; TERSMETTE KWF; FLOYD J; KERN SE; et al.
THE RELATIONSHIP OF MOLECULAR GENETIC ALTERATIONS AND ABNORMAL TOTAL DNA CONTENT IN COLORECTAL-CARCINOMA
0 2
113 3 51 128 1991 JAN [15] ONCOGENE 6(1):131-136
KERN SE; KINZLER KW; BAKER SJ; NIGRO JM; ROTTER V; et al.
MUTANT P53 PROTEINS BIND DNA ABNORMALLY INVITRO
6 159
114 3 41 121 1991 FEB 8 CELL 64(3):607-613
NIGRO JM; CHO KR; FEARON ER; KERN SE; RUPPERT JM; et al.
SCRAMBLED EXONS
2 74
115 7 37 125 1991 MAR [15] MOLECULAR AND CELLULAR BIOLOGY 11(3):1724-1728
RUPPERT JM; VOGELSTEIN B; KINZLER KW
THE ZINC FINGER PROTEIN GLI TRANSFORMS PRIMARY-CELLS IN COOPERATION WITH ADENOVIRUS E1A
0 75
116 8 43 131 1991 MAR 15 SCIENCE 251(4999):1366-1370
KINZLER KW; NILBERT MC; VOGELSTEIN B; BRYAN TM; LEVY DB; et al.
IDENTIFICATION OF A GENE LOCATED AT CHROMOSOME-5Q21 THAT IS MUTATED IN COLORECTAL CANCERS
25 495
117 7 54 132 1991 MAY 3 SCIENCE 252(5006):706-709
SIDRANSKY D; VONESCHENBACH A; TSAI YC; JONES P; SUMMERHAYES I; et al.
IDENTIFICATION OF P53 GENE-MUTATIONS IN BLADDER CANCERS AND URINE SAMPLES
16 674
118 5 65 122 1991 JUN 14 CELL 65(6):1083-1091
BARGONETTI J; FRIEDMAN PN; KERN SE; VOGELSTEIN B; PRIVES C
WILD-TYPE BUT NOT MUTANT P53 IMMUNOPURIFIED PROTEINS BIND TO SEQUENCES ADJACENT TO THE SV40 ORIGIN OF REPLICATION
5 339
119 1 21 116 1991 JUN [15] CANCER IMMUNOLOGY IMMUNOTHERAPY 33(4):267-273
ITAYA T; FEARON E; FIESINGER T; HUNT B; VOGELSTEIN B; et al.
IMMUNOGENICITY OF A NON-CLASS-I MHC EXPRESSING MURINE TUMOR TRANSFECTED WITH THE INFLUENZA-VIRUS HEMAGGLUTININ OR MURINE INTERLEUKIN-2 GENES
0 6
120 8 51 130 1991 JUN [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(11):4976-4980
MELTZER SJ; YIN J; HUANG Y; MCDANIEL TK; NEWKIRK C; et al.
REDUCTION TO HOMOZYGOSITY INVOLVING P53 IN ESOPHAGEAL CANCERS DEMONSTRATED BY THE POLYMERASE CHAIN-REACTION
1 180
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
121 8 35 133 1991 JUN 21 SCIENCE 252(5013):1708-1711
KERN SE; KINZLER KW; BRUSKIN A; JAROSZ D; FRIEDMAN P; et al.
IDENTIFICATION OF P53 AS A SEQUENCE-SPECIFIC DNA-BINDING PROTEIN
11 800
122 7 95 134 1991 JUL 5 SCIENCE 253(5015):49-53
HOLLSTEIN M; SIDRANSKY D; VOGELSTEIN B; HARRIS CC
P53 MUTATIONS IN HUMAN CANCERS
31 5145
123 5 36 123 1991 JUL 17 JOURNAL OF THE NATIONAL CANCER INSTITUTE 83(14):1004-1009
KOVACH JS; MCGOVERN RM; CASSADY JD; SWANSON SK; WOLD LE; et al.
DIRECT SEQUENCING FROM TOUCH PREPARATIONS OF HUMAN CARCINOMAS - ANALYSIS OF P53 MUTATIONS IN BREAST CARCINOMAS
0 96
124 8 59 135 1991 AUG 9 SCIENCE 253(5020):661-665
KINZLER KW; NILBERT MC; SU LK; VOGELSTEIN B; BRYAN TM; et al.
IDENTIFICATION OF FAP LOCUS GENES FROM CHROMOSOME-5Q21
33 1235
125 10 50 136 1991 AUG 9 SCIENCE 253(5020):665-669
NISHISHO I; NAKAMURA Y; MIYOSHI Y; MIKI Y; ANDO H; et al.
MUTATIONS OF CHROMOSOME-5Q21 GENES IN FAP AND COLORECTAL-CANCER PATIENTS
38 1000
126 2 43 117 1991 AUG 15 CANCER RESEARCH 51(16):4135-4140
PELTOMAKI P; SISTONEN P; MECKLIN JP; PYLKKANEN L; JARVINEN H; et al.
EVIDENCE SUPPORTING EXCLUSION OF THE DCC GENE AND A PORTION OF CHROMOSOME-18Q AS THE LOCUS FOR SUSCEPTIBILITY TO HEREDITARY NONPOLYPOSIS COLORECTAL-CARCINOMA IN 5 KINDREDS
3 42
127 5 20 118 1991 SEP 1 CANCER RESEARCH 51(17):4721-4723
SAYLORS RL; SIDRANSKY D; FRIEDMAN HS; BIGNER SH; BIGNER DD; et al.
INFREQUENT P53 GENE-MUTATIONS IN MEDULLOBLASTOMAS
0 130
128 0 0 112 1991 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 49(4):21-21
HEDGE PJ; MCKECHNIE D; GAMMACK A; FINNIEAR R; ELLSTON J; et al.
A 1.6MB YAC CONTIG AT THE FAP LOCUS (5Q21-Q22) CONTAINS THE GENE FOR MCC AND OTHER CANDIDATE GENES
0 0
129 0 0 113 1991 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 49(4):24-24
VOGELSTEIN B
GENETIC ALTERATIONS UNDERLYING COLORECTAL TUMORIGENESIS
0 0
130 0 0 114 1991 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 49(4):354-354
PELTOMAKI P; SISTONEN P; MECKLIN JP; PYLKKANEN L; JARVINEN H; et al.
EXCLUSION OF THE DCC GENE AND PART OF 18Q AS THE LOCUS FOR SUSCEPTIBILITY TO HEREDITARY NONPOLYPOSIS COLORECTAL-CARCINOMA IN 5 KINDREDS
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
131 0 0 115 1991 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 49(4):388-388
SCHNEIDER S; ZEHNBAUER B; VOGELSTEIN B; BRODEUR G
STRUCTURAL-ANALYSIS OF THE MYCN AMPLIFIED DOMAIN IN NEUROBLASTOMAS USING YEAST ARTIFICIAL-CHROMOSOME (YAC) CLONING
0 0
132 4 36 119 1991 OCT 15 CANCER RESEARCH 51(20):5449-5453
MILLIKIN D; MEESE E; VOGELSTEIN B; WITKOWSKI C; TRENT J
LOSS OF HETEROZYGOSITY FOR LOCI ON THE LONG ARM OF CHROMOSOME-6 IN HUMAN-MALIGNANT MELANOMA
0 180
133 5 47 129 1991 OCT [15] ONCOGENE 6(10):1791-1797
CASEY G; LOHSUEH M; LOPEZ ME; VOGELSTEIN B; STANBRIDGE EJ
GROWTH SUPPRESSION OF HUMAN BREAST-CANCER CELLS BY THE INTRODUCTION OF A WILD-TYPE P53 GENE
1 228
134 7 53 120 1991 DEC 1 CANCER RESEARCH 51(23):6304-6311
KASTAN MB; ONYEKWERE O; SIDRANSKY D; VOGELSTEIN B; CRAIG RW
PARTICIPATION OF P53 PROTEIN IN THE CELLULAR-RESPONSE TO DNA DAMAGE
12 3035
135 1 2 126 1991 DEC 25 NUCLEIC ACIDS RESEARCH 19(24):6965-6965
DEVILEE P; VANVLIET M; CHO KR; VOGELSTEIN B
HINDIII POLYMORPHISM IN THE DCC GENE
0 5
136 1 2 127 1991 DEC 25 NUCLEIC ACIDS RESEARCH 19(24):6983-6983
PARRY PJ; MARKIE D; FEARON ER; NIGRO JM; VOGELSTEIN B; et al.
PCR-BASED DETECTION OF 2 MSPI POLYMORPHIC SITES AT D18S8
0 14
137 6 19 153 1992 JAN [15] JAPANESE JOURNAL OF CANCER RESEARCH 83(1):10-14
MIYOSHI Y; NISHISHO I; MIKI Y; MORI T; KINZLER KW; et al.
INSERTION DELETION POLYMORPHISM AND OTHER RESTRICTION-FRAGMENT-LENGTH-POLYMORPHISMS IN THE MCC GENE
1 4
138 0 0 156 1992 JAN [15] LABORATORY INVESTIGATION 66(1):A46-A46
MULDER JWR; OFFERHAUS GJA; DEFEYTER EP; FLOYD JF; KERN SE; et al.
THE RELATIONSHIP OF QUANTITATIVE NUCLEAR MORPHOLOGY TO MOLECULAR GENETIC ALTERATIONS IN THE ADENOMA-CARCINOMA SEQUENCE OF THE LARGE-BOWEL
0 0
139 0 0 157 1992 JAN [15] LABORATORY INVESTIGATION 66(1):A47-A47
REDSTON MS; KERN SE; VOGELSTEIN B; HAMILTON SR
EXPRESSION OF OA519 (HAPTOGLOBIN-RELATED PROTEIN EPITOPES) IN COLORECTAL CARCINOMAS - COMPARISON WITH MOLECULAR GENETIC ALTERATIONS AND METASTASIS
0 3
140 2 10 161 1992 JAN 16 NATURE 355(6357):209-210
VOGELSTEIN B; KINZLER KW
CANCER - CARCINOGENS LEAVE FINGERPRINTS
0 126
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
141 6 25 141 1992 FEB 1 CANCER RESEARCH 52(3):643-645
MIKI Y; NISHISHO I; HORII A; MIYOSHI Y; UTSUNOMIYA J; et al.
DISRUPTION OF THE APC GENE BY A RETROTRANSPOSAL INSERTION OF L1 SEQUENCE IN A COLON CANCER
0 155
142 5 15 162 1992 FEB 27 NATURE 355(6363):846-848
SIDRANSKY D; MIKKELSEN T; SCHWECHHEIMER K; ROSENBLUM ML; CAVANEE W; et al.
CLONAL EXPANSION OF P53 MUTANT-CELLS IS ASSOCIATED WITH BRAIN-TUMOR PROGRESSION
3 561
143 9 34 166 1992 MAR 12 NEW ENGLAND JOURNAL OF MEDICINE 326(11):737-740
SIDRANSKY D; FROST P; VONESCHENBACH A; OYASU R; PREISINGER AC; et al.
CLONAL ORIGIN OF BLADDER-CANCER
2 312
144 6 26 147 1992 MAR [15] CHEST 101(3):S19-S20
BENNETT WP; HOLLSTEIN MC; HSU IC; SIDRANSKY D; LANE DP; et al.
MUTATIONAL SPECTRA AND IMMUNOHISTOCHEMICAL ANALYSES OF P53 IN HUMAN CANCERS
0 7
145 7 41 158 1992 MAR [15] MOLECULAR AND CELLULAR BIOLOGY 12(3):1357-1365
NIGRO JM; SIKORSKI R; REED SI; VOGELSTEIN B
HUMAN P53 AND CDC2HS GENES COMBINE TO INHIBIT THE PROLIFERATION OF SACCHAROMYCES-CEREVISIAE
5 85
146 11 55 159 1992 MAR [15] MOLECULAR AND CELLULAR BIOLOGY 12(3):1387-1395
GOYETTE MC; CHO K; FASCHING CL; LEVY DB; KINZLER KW; et al.
PROGRESSION OF COLORECTAL-CANCER IS ASSOCIATED WITH MULTIPLE TUMOR SUPPRESSOR GENE DEFECTS BUT INHIBITION OF TUMORIGENICITY IS ACCOMPLISHED BY CORRECTION OF ANY SINGLE DEFECT VIA CHROMOSOME TRANSFER
6 212
147 4 54 168 1992 MAR [15] ONCOGENE 7(3):553-561
NARAYANAN R; LAWLOR KG; SCHAAPVELD RQJ; CHO KR; VOGELSTEIN B; et al.
ANTISENSE RNA TO THE PUTATIVE TUMOR-SUPPRESSOR GENE DCC TRANSFORMS RAT-1 FIBROBLASTS
2 83
148 2 32 142 1992 APR 1 CANCER RESEARCH 52(7):1780-1785
FONG CT; WHITE PS; PETERSON K; SAPIENZA C; CAVENEE WK; et al.
LOSS OF HETEROZYGOSITY FOR CHROMOSOME-1 OR CHROMOSOME-14 DEFINES SUBSETS OF ADVANCED NEUROBLASTOMAS
0 164
149 7 56 169 1992 APR 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(7):2759-2763
GERWIN BI; SPILLARE E; FORRESTER K; LEHMAN TA; KISPERT J; et al.
MUTANT-P53 CAN INDUCE TUMORIGENIC CONVERSION OF HUMAN BRONCHIAL EPITHELIAL-CELLS AND REDUCE THEIR RESPONSIVENESS TO A NEGATIVE GROWTH-FACTOR, TRANSFORMING GROWTH FACTOR-BETA(1)
0 116
150 4 29 170 1992 APR 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(7):2965-2969
WONG AJ; RUPPERT JM; BIGNER SH; GRZESCHIK CH; HUMPHREY PA; et al.
STRUCTURAL ALTERATIONS OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR GENE IN HUMAN GLIOMAS
0 269
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
151 8 46 172 1992 APR 3 SCIENCE 256(5053):102-105
SIDRANSKY D; TOKINO T; HAMILTON SR; KINZLER KW; LEVIN B; et al.
IDENTIFICATION OF RAS ONCOGENE MUTATIONS IN THE STOOL OF PATIENTS WITH CURABLE COLORECTAL TUMORS
8 468
152 10 20 165 1992 APR [15] NATURE GENETICS 1(1):45-49
ELDEIRY WS; KERN SE; PIETENPOL JA; KINZLER KW; VOGELSTEIN B
DEFINITION OF A CONSENSUS BINDING-SITE FOR P53
15 990
153 6 26 173 1992 MAY 1 SCIENCE 256(5057):668-670
SU LK; KINZLER KW; VOGELSTEIN B; PREISINGER AC; MOSER AR; et al.
MULTIPLE INTESTINAL NEOPLASIA CAUSED BY A MUTATION IN THE MURINE HOMOLOG OF THE APC GENE
14 528
154 12 49 174 1992 MAY 8 SCIENCE 256(5058):827-830
KERN SE; PIETENPOL JA; THIAGALINGAM S; SEYMOUR A; KINZLER KW; et al.
ONCOGENIC FORMS OF P53 INHIBIT P53-REGULATED GENE-EXPRESSION
11 850
155 7 21 143 1992 MAY 15 CANCER RESEARCH 52(10):2984-2986
SIDRANSKY D; TOKINO T; HELZLSOUER K; ZEHNBAUER B; RAUSCH G; et al.
INHERITED P53 GENE-MUTATIONS IN BREAST-CANCER
1 147
156 8 41 150 1992 MAY [15] GASTROENTEROLOGY 102(5):1612-1619
OFFERHAUS GJA; DEFEYTER EP; CORNELISSE CJ; TERSMETTE KWF; FLOYD J; et al.
THE RELATIONSHIP OF DNA ANEUPLOIDY TO MOLECULAR GENETIC ALTERATIONS IN COLORECTAL-CARCINOMA
2 105
157 6 26 171 1992 MAY 15 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(10):4452-4456
MIYOSHI Y; ANDO H; NAGASE H; NISHISHO I; HORII A; et al.
GERM-LINE MUTATIONS OF THE APC GENE IN 53 FAMILIAL ADENOMATOUS POLYPOSIS PATIENTS
9 358
158 5 22 148 1992 [JUN 30] COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 57:345-351
HEDRICK L; CHO KR; BOYD J; RISINGER J; VOGELSTEIN B
DCC - A TUMOR-SUPPRESSOR GENE EXPRESSED ON THE CELL-SURFACE
3 25
159 1 11 149 1992 [JUN 30] CYTOGENETICS AND CELL GENETICS 61(4):237-242
PLAETKE R; WEBER J; WOOD S; DEAN M; JEFFREYS AJ; et al.
REPORT OF THE 2ND INTERNATIONAL WORKSHOP ON HUMAN CHROMOSOME-5 MAPPING - CONSENSUS GENETIC-MAP
0 2
160 10 25 154 1992 [JUN 30] JOURNAL OF CELLULAR BIOCHEMISTRY :137-141
CHO KR; VOGELSTEIN B
SUPPRESSOR GENE ALTERATIONS IN THE COLORECTAL ADENOMA-CARCINOMA SEQUENCE
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
161 11 31 163 1992 JUL 2 NATURE 358(6381):80-83
OLINER JD; KINZLER KW; MELTZER PS; GEORGE DL; VOGELSTEIN B
AMPLIFICATION OF A GENE ENCODING A P53-ASSOCIATED PROTEIN IN HUMAN SARCOMAS
12 1226
162 0 0 167 1992 AUG 6 NEW ENGLAND JOURNAL OF MEDICINE 327(6):434-434
SIDRANSKY D; VOGELSTEIN B; FROST P; VONESCHENBACH AC
MONOCLONALITY OF MULTIPLE BLADDER CANCERS - REPLY
0 0
163 6 23 144 1992 AUG 15 CANCER RESEARCH 52(16):4530-4533
PELTOMAKI P; SISTONEN P; MECKLIN JP; PYLKKANEN L; AALTONEN L; et al.
EVIDENCE THAT THE MCC-APC GENE REGION IN 5Q21 IS NOT THE SITE FOR SUSCEPTIBILITY TO HEREDITARY NONPOLYPOSIS COLORECTAL-CARCINOMA
1 27
164 5 66 151 1992 AUG [15] GENOMICS 13(4):1281-1288
JUSTICE MJ; GILBERT DJ; KINZLER KW; VOGELSTEIN B; BUCHBERG AM; et al.
A MOLECULAR GENETIC-LINKAGE MAP OF MOUSE CHROMOSOME-18 REVEALS EXTENSIVE LINKAGE CONSERVATION WITH HUMAN CHROMOSOME-5 AND CHROMOSOME-18
1 53
165 8 31 145 1992 AUG 21 CELL 70(4):523-526
VOGELSTEIN B; KINZLER KW
P53 FUNCTION AND DYSFUNCTION
13 1626
166 7 92 139 1992 SEP 1 CANCER 70(5):1300-1312
LYNCH HT; WATSON P; SMYRK TC; LANSPA SJ; BOMAN BM; et al.
COLON CANCER GENETICS
0 26
167 13 38 140 1992 SEP 15 CANCER 70(6):1727-1731
CHO KR; VOGELSTEIN B
GENETIC ALTERATIONS IN THE ADENOMA CARCINOMA SEQUENCE
0 144
168 1 7 155 1992 SEP [15] JOURNAL OF SURGICAL ONCOLOGY 51(1):5-7
SHAH KV; DANIEL RW; SIMONS JW; VOGELSTEIN B
INVESTIGATION OF COLON CANCERS FOR HUMAN PAPILLOMAVIRUS GENOMIC SEQUENCES BY POLYMERASE CHAIN-REACTION
0 6
169 11 22 164 1992 SEP 17 NATURE 359(6392):235-237
POWELL SM; ZILZ N; BEAZERBARCLAY Y; BRYAN TM; HAMILTON SR; et al.
APC MUTATIONS OCCUR EARLY DURING COLORECTAL TUMORIGENESIS
27 793
170 10 44 137 1992 OCT [15] AMERICAN JOURNAL OF PATHOLOGY 141(4):797-804
MULDER JWR; OFFERHAUS GJA; DEFEYTER EP; FLOYD JJ; KERN SE; et al.
THE RELATIONSHIP OF QUANTITATIVE NUCLEAR MORPHOLOGY TO MOLECULAR GENETIC ALTERATIONS IN THE ADENOMA-CARCINOMA SEQUENCE OF THE LARGE-BOWEL
0 40
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
171 6 19 175 1992 OCT [15] TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 168(2):141-147
NAKAMURA Y; NISHISHO I; KINZLER KW; VOGELSTEIN B; MIYOSHI Y; et al.
MUTATIONS OF THE APC (ADENOMATOUS-POLYPOSIS-COLI) GENE IN FAP (FAMILIAL-POLYPOSIS-COLI) PATIENTS AND IN SPORADIC COLORECTAL TUMORS
0 11
172 3 3 138 1992 OCT 28 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 660:283-285
LAWLOR KG; TELANG NT; OSBORNE MP; SCHAAPVELD RQ; CHO KR; et al.
ANTISENSE RNA TO THE PUTATIVE TUMOR SUPPRESSOR GENE DELETED IN COLORECTAL-CANCER TRANSFORMS FIBROBLASTS
0 2
173 7 56 146 1992 NOV 13 CELL 71(4):587-597
KASTAN MB; ZHAN QM; ELDEIRY WS; CARRIER F; JACKS T; et al.
A MAMMALIAN-CELL CYCLE CHECKPOINT PATHWAY UTILIZING P53 AND GADD45 IS DEFECTIVE IN ATAXIA-TELANGIECTASIA
12 2526
174 0 0 152 1992 NOV 15 HOSPITAL PRACTICE 27(11):51-58
KINZLER KW; VOGELSTEIN B
THE COLORECTAL-CANCER GENE HUNT - CURRENT FINDINGS
1 9
175 4 63 160 1992 DEC [15] MOLECULAR AND CELLULAR BIOLOGY 12(12):5563-5570
SCHNEIDER SS; HIEMSTRA JL; ZEHNBAUER BA; TAILLONMILLER P; LEPASLIER DL; et al.
ISOLATION AND STRUCTURAL-ANALYSIS OF A 1.2-MEGABASE N-MYC AMPLICON FROM A HUMAN NEUROBLASTOMA
0 38
176 8 29 182 1993 JAN [15] GENOMICS 15(1):3-8
LUONGO C; GOULD KA; SU LK; KINZLER KW; VOGELSTEIN B; et al.
MAPPING OF MULTIPLE INTESTINAL NEOPLASIA (MIN) TO PROXIMAL CHROMOSOME-18 OF THE MOUSE
0 44
177 0 0 184 1993 JAN [15] LABORATORY INVESTIGATION 68(1):A43-A43
BAAS IO; MULDER JWR; OFFERHAUS GJA; VOGELSTEIN B; HAMILTON SR
IMMUNOHISTOCHEMISTRY OF ALTERED-P53 SUPPRESSOR GENE-PRODUCT IN COLORECTAL NEOPLASMS
0 0
178 6 27 189 1993 APR 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(7):2846-2850
SMITH KJ; JOHNSON KA; BRYAN TM; HILL DE; MARKOWITZ S; et al.
THE APC GENE-PRODUCT IN NORMAL AND TUMOR-CELLS
21 320
179 3 25 193 1993 APR [15] TRENDS IN GENETICS 9(4):138-141
VOGELSTEIN B; KINZLER KW
THE MULTISTEP NATURE OF CANCER
2 758
180 6 27 185 1993 APR 29 NATURE 362(6423):857-860
OLINER JD; PIETENPOL JA; THIAGALINGAM S; GVURIS J; KINZLER KW; et al.
ONCOPROTEIN MDM2 CONCEALS THE ACTIVATION DOMAIN OF TUMOR SUPPRESSOR-P53
6 755
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
181 3 69 176 1993 MAY 1 CANCER RESEARCH 53(9):1986-1989
LEACH FS; ELLEDGE SJ; SHERR CJ; WILLSON JKV; MARKOWITZ S; et al.
AMPLIFICATION OF CYCLIN GENES IN COLORECTAL CARCINOMAS
1 174
182 6 32 190 1993 MAY 7 SCIENCE 260(5109):810-812
PELTOMAKI P; AALTONEN LA; SISTONEN P; PYLKKANEN L; MECKLIN JP; et al.
GENETIC-MAPPING OF A LOCUS PREDISPOSING TO HUMAN COLORECTAL-CANCER
15 626
183 9 38 191 1993 MAY 7 SCIENCE 260(5109):812-816
AALTONEN LA; PELTOMAKI P; LEACH FS; SISTONEN P; PYLKKANEN L; et al.
CLUES TO THE PATHOGENESIS OF FAMILIAL COLORECTAL-CANCER
36 1811
184 8 25 177 1993 MAY 15 CANCER RESEARCH 53(10):2231-2234
LEACH FS; TOKINO T; MELTZER P; BURRELL M; OLINER JD; et al.
P53 MUTATION AND MDM2 AMPLIFICATION IN HUMAN SOFT-TISSUE SARCOMAS
1 388
185 0 15 186 1993 JUN 10 NATURE 363(6429):495-496
KINZLER KW; VOGELSTEIN B
CANCER - A GENE FOR NEUROFIBROMATOSIS-2
0 12
186 7 24 178 1993 JUN 15 CANCER RESEARCH 53(12):2728-2731
SU LK; JOHNSON KA; SMITH KJ; HILL DE; VOGELSTEIN B; et al.
ASSOCIATION BETWEEN WILD-TYPE AND MUTANT APC GENE-PRODUCTS
6 148
187 6 22 183 1993 OCT [15] INTERNATIONAL JOURNAL OF ONCOLOGY 3(4):769-772
TOKINO T; DAVIDSON N; HELZLSOUER K; ZEHNBAUER B; NAKAMURA Y; et al.
ABSENCE OF GERMLINE PROHIBITIN MUTATIONS IN EARLY-ONSET BREAST-CANCER
0 7
188 7 31 188 1993 NOV 11 NUCLEIC ACIDS RESEARCH 21(22):5192-5197
OLINER JD; KINZLER KW; VOGELSTEIN B
IN-VIVO CLONING OF PCR PRODUCTS IN ESCHERICHIA-COLI
0 36
189 14 73 179 1993 NOV 19 CELL 75(4):817-825
ELDEIRY WS; TOKINO T; VELCULESCU VE; LEVY DB; PARSONS R; et al.
WAF1, A POTENTIAL MEDIATOR OF P53 TUMOR SUPPRESSION
24 4823
190 7 42 192 1993 DEC 10 SCIENCE 262(5140):1734-1737
SU LK; VOGELSTEIN B; KINZLER KW
ASSOCIATION OF THE APC TUMOR-SUPPRESSOR PROTEIN WITH CATENINS
17 832
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
191 9 61 180 1993 DEC 17 CELL 75(6):1215-1225
LEACH FS; NICOLAIDES NC; PAPADOPOULOS N; LIU B; JEN J; et al.
MUTATIONS OF A MUTS HOMOLOG IN HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER
32 1578
192 4 41 181 1993 DEC 17 CELL 75(6):1227-1236
PARSONS R; LI GM; LONGLEY MJ; FANG WH; PAPADOPOULOS N; et al.
HYPERMUTABILITY AND MISMATCH REPAIR DEFICIENCY IN RER+ TUMOR-CELLS
24 732
193 6 38 187 1993 DEC 30 NEW ENGLAND JOURNAL OF MEDICINE 329(27):1982-1987
POWELL SM; PETERSEN GM; KRUSH AJ; BOOKER S; JEN J; et al.
MOLECULAR DIAGNOSIS OF FAMILIAL ADENOMATOUS POLYPOSIS
25 451
194 6 37 217 1994 JAN [15] JOURNAL OF PATHOLOGY 172(1):5-12
BAAS IO; MULDER JWR; OFFERHAUS GJA; VOGELSTEIN B; HAMILTON SR
EVALUATION OF 6 ANTIBODIES FOR IMMUNOHISTOCHEMISTRY OF MUTANT P53 GENE-PRODUCT IN ARCHIVAL COLORECTAL NEOPLASMS
1 373
195 0 0 215 1994 FEB 13 JOURNAL OF CELLULAR BIOCHEMISTRY :163-163
PIETENPOL J; VOGELSTEIN B
P53 FUNCTION AND DYSFUNCTION
0 0
196 9 23 211 1994 FEB [15] GENOMICS 19(3):525-531
CHO KR; OLINER JD; SIMONS JW; HEDRICK L; FEARON ER; et al.
THE DCC GENE - STRUCTURAL-ANALYSIS AND MUTATIONS IN COLORECTAL CARCINOMAS
2 149
197 5 31 199 1994 MAR 1 CANCER RESEARCH 54(5):1169-1174
ELDEIRY WS; HARPER JW; OCONNOR PM; VELCULESCU VE; CANMAN CE; et al.
WAF1/CIP1 IS INDUCED IN P53-MEDIATED G(1) ARREST AND APOPTOSIS
11 1538
198 3 43 214 1994 MAR [15] JOURNAL OF CELL BIOLOGY 124(6):1017-1027
PIERCEALL WE; CHO KR; GETZENBERG RH; REALE MA; HEDRICK L; et al.
NIH3T3 CELLS EXPRESSING THE DELETED IN COLORECTAL-CANCER TUMOR-SUPPRESSOR GENE-PRODUCT STIMULATE NEURITE OUTGROWTH IN RAT PC12 PHEOCHROMOCYTOMA CELLS
1 43
199 5 32 224 1994 MAR 15 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91(6):1998-2002
PIETENPOL JA; TOKINO T; THIAGALINGAM S; ELDEIRY WS; KINZLER KW; et al.
SEQUENCE-SPECIFIC TRANSCRIPTIONAL ACTIVATION IS ESSENTIAL FOR GROWTH SUPPRESSION BY P53
10 337
200 5 35 227 1994 MAR 18 SCIENCE 263(5153):1625-1629
PAPADOPOULOS N; NICOLAIDES NC; WEI YF; RUBEN SM; CARTER KC; et al.
MUTATION OF A MUTL HOMOLOG IN HEREDITARY COLON-CANCER
26 1258
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
201 9 35 225 1994 MAR 29 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91(7):2684-2688
CHEN CY; OLINER JD; ZHAN QM; FORNACE AJ; VOGELSTEIN B; et al.
INTERACTIONS BETWEEN P53 AND MDM2 IN A MAMMALIAN-CELL CYCLE CHECKPOINT PATHWAY
1 253
202 5 26 200 1994 APR 1 CANCER RESEARCH 54(7):1645-1648
AALTONEN LA; PELTOMAKI P; MECKLIN JP; JARVINEN H; JASS JR; et al.
REPLICATION ERRORS IN BENIGN AND MALIGNANT-TUMORS FROM HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER PATIENTS
11 406
203 7 27 210 1994 MAY 15 GENES & DEVELOPMENT 8(10):1174-1183
HEDRICK L; CHO KR; FEARON ER; WU TC; KINZLER KW; et al.
THE DCC GENE-PRODUCT IN CELLULAR-DIFFERENTIATION AND COLORECTAL TUMORIGENESIS
0 129
204 13 32 208 1994 [JUN 30] COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 59:517-521
VOGELSTEIN B; KINZLER KW
COLORECTAL-CANCER AND THE INTERSECTION BETWEEN BASIC AND CLINICAL RESEARCH
0 29
205 0 5 209 1994 [JUN 30] COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 59:585-587
LISITSYN NA; LEACH FS; VOGELSTEIN B; WIGLER MH
DETECTION OF GENETIC LOSS IN TUMORS BY REPRESENTATIONAL DIFFERENCE ANALYSIS
1 9
206 3 27 216 1994 [JUN 30] JOURNAL OF NEURO-ONCOLOGY 20(1):55-58
ARTHUR RR; GROSSMAN SA; RONNETT BM; BIGNER SH; VOGELSTEIN B; et al.
LACK OF ASSOCIATION OF HUMAN POLYOMAVIRUSES WITH HUMAN BRAIN-TUMORS
0 25
207 0 1 221 1994 JUL 7 NEW ENGLAND JOURNAL OF MEDICINE 331(1):49-50
KINZLER KW; VOGELSTEIN B
CLINICAL IMPLICATIONS OF BASIC RESEARCH - CANCER-THERAPY MEETS P53
0 73
208 11 38 195 1994 JUL [15] AMERICAN JOURNAL OF PATHOLOGY 145(1):148-156
KIM HG; JEN J; VOGELSTEIN B; HAMILTON SR
CLINICAL AND PATHOLOGICAL CHARACTERISTICS OF SPORADIC COLORECTAL CARCINOMAS WITH DNA-REPLICATION ERRORS IN MICROSATELLITE SEQUENCES
4 446
209 9 27 201 1994 JUL 15 CANCER RESEARCH 54(14):3672-3675
SMITH KJ; LEVY DB; MAUPIN P; POLLARD TD; VOGELSTEIN B; et al.
WILD-TYPE BUT NOT MUTANT APC ASSOCIATES WITH THE MICROTUBULE CYTOSKELETON
8 230
210 4 33 202 1994 JUL 15 CANCER RESEARCH 54(14):3714-3717
PIETENPOL JA; PAPADOPOULOS N; MARKOWITZ S; WILLSON JKV; KINZLER KW; et al.
PARADOXICAL INHIBITION OF SOLID TUMOR-CELL GROWTH BY BCL2
2 131
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
211 1 15 219 1994 JUL 21 NATURE 370(6486):174-175
VOGELSTEIN B; KINZLER KW
TUMOR-SUPPRESSOR GENES - X-RAYS STRIKE P53 AGAIN
0 44
212 13 57 222 1994 JUL 28 NEW ENGLAND JOURNAL OF MEDICINE 331(4):213-221
JEN J; KIM HG; PIANTADOSI S; LIU ZF; LEVITT RC; et al.
ALLELIC LOSS OF CHROMOSOME 18Q AND PROGNOSIS IN COLORECTAL-CANCER
14 419
213 9 36 203 1994 SEP 1 CANCER RESEARCH 54(17):4590-4594
LIU B; PARSONS RE; HAMILTON SR; PETERSEN GM; LYNCH HT; et al.
HMSH2 MUTATIONS IN HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER KINDREDS
12 327
214 7 29 220 1994 SEP 1 NATURE 371(6492):75-80
NICOLAIDES NC; PAPADOPOULOS N; LIU B; WEI YF; CARTER KC; et al.
MUTATIONS OF 2 PMS HOMOLOGS IN HEREDITARY NONPOLYPOSIS COLON-CANCER
14 979
215 5 53 226 1994 SEP 13 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91(19):9009-9013
UEBA T; NOSAKA T; TAKAHASHI JA; SHIBATA F; FLORKIEWICZ RZ; et al.
TRANSCRIPTIONAL REGULATION OF BASIC FIBROBLAST GROWTH-FACTOR GENE BY P53 IN HUMAN GLIOBLASTOMA AND HEPATOCELLULAR-CARCINOMA CELLS
0 104
216 10 32 212 1994 SEP [15] HUMAN MOLECULAR GENETICS 3(9):1537-1542
TOKINO T; THIAGALINGAM S; ELDEIRY WS; WALDMAN T; KINZLER KW; et al.
P53 TAGGED SITES FROM HUMAN GENOMIC DNA
1 102
217 3 16 218 1994 SEP 21 JOURNAL OF THE NATIONAL CANCER INSTITUTE 86(18):1417-1419
LYNCH HT; DROUHARD T; LANSPA S; SMYRK T; LYNCH P; et al.
MUTATION OF AN MUTL HOMOLOG IN A NAVAJO FAMILY WITH HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER
0 16
218 0 21 207 1994 OCT 7 CELL 79(1):1-3
VOGELSTEIN B; KINZLER KW
HAS THE BREAST-CANCER GENE BEEN FOUND
0 43
219 5 36 194 1994 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 55(4):659-665
NYSTROMLAHTI M; PARSONS R; SISTONEN P; PYLKKANEN L; AALTONEN LA; et al.
MISMATCH REPAIR GENES ON CHROMOSOMES 2P AND 3P ACCOUNT FOR A MAJOR SHARE OF HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER FAMILIES EVALUABLE BY LINKAGE
3 109
220 6 23 204 1994 NOV 1 CANCER RESEARCH 54(21):5523-5526
JEN J; POWELL SM; PAPADOPOULOS N; SMITH KJ; HAMILTON SR; et al.
MOLECULAR DETERMINANTS OF DYSPLASIA IN COLORECTAL LESIONS
12 308
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
221 0 0 196 1994 NOV 15 BLOOD 84(10):A292-A292
SATO Y; SUTO Y; PIETENPOL J; GOLUB TR; GILLILAND DG; et al.
TEL AND THE GENE FOR P27KIP1 ARE FREQUENTLY DEPLETED IN PATIENTS WITH 12P13 REARRANGEMENTS AND HEMATOPOIETIC MALIGNANCIES
0 5
222 0 0 197 1994 NOV 15 BLOOD 84(10):A613-A613
SHIOHARA M; ELDIERY WS; WADA M; NAKAMAKI T; TAKEUCHI S; et al.
ABSENCE OF WAF1 MUTATIONS IN A VARIETY OF HUMAN MALIGNANCIES
0 0
223 9 35 205 1994 NOV 15 CANCER RESEARCH 54(22):5953-5958
LEVY DB; SMITH KJ; BEAZERBARCLAY Y; HAMILTON SR; VOGELSTEIN B; et al.
INACTIVATION OF BOTH APC ALLELES IN HUMAN AND MOUSE-TUMORS
5 152
224 1 1 213 1994 NOV [15] HUMAN MOLECULAR GENETICS 3(11):2082-2082
LEACH FS; NICOLAIDES NC; SISTONEN P; YU JW; KAO FT; et al.
3 DINUCLEOTIDE REPEAT POLYMORPHISMS PROXIMAL TO THE D2S123 LOCUS
0 7
225 7 46 198 1994 DEC 1 BLOOD 84(11):3781-3784
SHIOHARA M; ELDEIRY WS; WADA M; NAKAMAKI T; TAKEUCHI S; et al.
ABSENCE OF WAF1 MUTATIONS IN A VARIETY OF HUMAN MALIGNANCIES
1 294
226 1 3 223 1994 DEC 8 NEW ENGLAND JOURNAL OF MEDICINE 331(23):1592-1592
HAMILTON SR; JEN J; VOGELSTEIN B
ALLELES LOST AND GAINED IN MALIGNANT-CELLS - REPLY
0 0
227 3 41 206 1994 DEC 15 CANCER RESEARCH 54(24):6353-6358
JEN J; HARPER JW; BIGNER SH; BIGNER DD; PAPADOPOULOS N; et al.
DELETION OF P16 AND P15 GENES IN BRAIN-TUMORS
3 400
228 5 30 251 1995 JAN 5 ONCOGENE 10(1):33-37
ESHLEMAN JR; LANG EZ; BOWERFIND GK; PARSONS R; VOGELSTEIN B; et al.
INCREASED MUTATION-RATE AT THE HPRT LOCUS ACCOMPANIES MICROSATELLITE INSTABILITY IN COLON-CANCER
9 171
229 3 14 246 1995 JAN [15] NATURE GENETICS 9(1):10-11
DACOSTA LT; LIU B; ELDEIRY WS; HAMILTON SR; KINZLER KW; et al.
POLYMERASE-DELTA VARIANTS IN RER COLORECTAL TUMORS
3 99
230 10 37 247 1995 JAN [15] NATURE GENETICS 9(1):48-55
LIU B; NICOLAIDES NC; MARKOWITZ S; WILLSON JKV; PARSONS RE; et al.
MISMATCH REPAIR GENE DEFECTS IN SPORADIC COLORECTAL CANCERS WITH MICROSATELLITE INSTABILITY
15 567
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
231 0 0 244 1995 FEB [15] JOURNAL OF MEDICAL GENETICS 32(2):146-146
FROGGATT NJ; KOCH DJ; DAVIES R; EVANS DGR; PARSONS R; et al.
MOLECULAR-GENETIC ANALYSIS OF HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER SYNDROME
0 0
232 6 36 229 1995 MAR 15 CANCER RESEARCH 55(6):1206-1210
PIETENPOL JA; BOHLANDER SK; SATO Y; PAPADOPOULOS N; LIU B; et al.
ASSIGNMENT OF THE HUMAN P27(KIP1) GENE TO 12P13 AND ITS ANALYSIS IN LEUKEMIAS
1 194
233 0 0 253 1995 MAR 17 SCIENCE 267(5204):1609-1618
WEINTRAUB H; ASHBURNER M; GOODFELLOW PN; LODISH HF; ARNTZEN CJ; et al.
THROUGH THE GLASS LIGHTLY
0 2
234 15 72 250 1995 MAR 30 NEW ENGLAND JOURNAL OF MEDICINE 332(13):839-847
HAMILTON SR; LIU B; PARSONS RE; PAPADOPOULOS N; JEN J; et al.
THE MOLECULAR-BASIS OF TURCOTS-SYNDROME
5 345
235 0 0 238 1995 APR [15] GASTROENTEROLOGY 108(4):A478-A478
HAMILTON SR; LIU B; PARSONS RE; PAPADOPOLOUS NC; JEN J; et al.
THE MOLECULAR-BASIS OF TURCOT SYNDROME
0 0
236 0 0 239 1995 APR [15] GASTROENTEROLOGY 108(4):A520-A520
OLSCHWANG S; LAURENTPUIG P; BOISSON C; VOGELSTEIN B; THOMAS G
HMSH2 GERMLINE MUTATIONS SCREENING IN 50 FAMILIAL CANCER AGGREGATIONS
0 1
237 2 39 240 1995 APR 15 GENES & DEVELOPMENT 9(8):935-944
MACLEOD KF; SHERRY N; HANNON G; BEACH D; TOKINO T; et al.
P53-DEPENDENT AND INDEPENDENT EXPRESSION OF P21 DURING CELL-GROWTH, DIFFERENTIATION, AND DNA-DAMAGE
2 609
238 0 0 237 1995 APR 24 FASEB JOURNAL 9(6):A1258-A1258
NICOLAIDES NC; KINZLER KW; VOGELSTEIN B
MUTATIONS OF MISMATCH REPAIR GENES IN HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER
0 0
239 11 33 254 1995 MAY 5 SCIENCE 268(5211):738-740
PARSONS R; LI GM; LONGLEY M; MODRICH P; LIU B; et al.
MISMATCH REPAIR DEFICIENCY IN PHENOTYPICALLY NORMAL HUMAN-CELLS
3 241
240 7 42 243 1995 MAY [15] INTERNATIONAL JOURNAL OF ONCOLOGY 6(5):937-946
ZHAN QM; ELDEIRY W; BAE I; ALAMO I; KASTAN MB; et al.
SIMILARITY OF THE DNA-DAMAGE RESPONSIVENESS AND GROWTH-SUPPRESSIVE PROPERTIES OF WAF1/CIP1 AND GADD45
0 43
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
241 6 36 255 1995 JUN 2 SCIENCE 268(5215):1336-1338
MARKOWITZ S; WANG J; MYEROFF L; PARSONS R; SUN LZ; et al.
INACTIVATION OF THE TYPE-II TGF-BETA RECEPTOR IN COLON-CANCER CELLS WITH MICROSATELLITE INSTABILITY
20 1336
242 9 37 252 1995 JUN 20 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92(13):6062-6066
THIAGALINGAM S; KINZLER KW; VOGELSTEIN B
PAK1, A GENE THAT CAN REGULATE P53 ACTIVITY IN YEAST
0 20
243 0 0 245 1995 JUN 21 JOURNAL OF THE NATIONAL CANCER INSTITUTE 87(12):877-883
BISHOP JM; CALABRESI P; ANTMAN K; BALTIMORE D; FOLKMAN J; et al.
NCI INTRAMURAL PROGRAM REVIEW COMPLETE - PUBLIC COMMENT SOUGHT ON RECOMMENDATIONS
0 0
244 4 22 236 1995 [JUN 30] CYTOGENETICS AND CELL GENETICS 71(4):343-344
TRENT JM; WILTSHIRE R; SU LK; NICOLAIDES NC; VOGELSTEIN B; et al.
THE GENE FOR THE APC-BINDING PROTEIN BETA-CATENIN (CTNNB1) MAPS TO CHROMOSOME 3P22, A REGION FREQUENTLY ALTERED IN HUMAN MALIGNANCIES
0 17
245 7 27 256 1995 JUN 30 SCIENCE 268(5219):1915-1917
PAPADOPOULOS N; NICOLAIDES NC; LIU B; PARSONS R; LENGAUER C; et al.
MUTATIONS OF GTBP IN GENETICALLY UNSTABLE CELLS
9 385
246 13 58 230 1995 JUL 1 CANCER RESEARCH 55(13):2910-2919
ELDEIRY WS; TOKINO T; WALDMAN T; OLINER JD; VELCULESCU VE; et al.
TOPOLOGICAL CONTROL OF P21(WAF1/CIP1) EXPRESSION IN NORMAL AND NEOPLASTIC TISSUES
5 441
247 10 33 231 1995 JUL 15 CANCER RESEARCH 55(14):2972-2977
SU LK; BURRELL M; HILL DE; GYURIS J; BRENT R; et al.
APC BINDS TO THE NOVEL PROTEIN EB1
5 185
248 0 36 228 1995 AUG 15 BLOOD 86(4):1525-1533
SATO Y; SUTO Y; PIETENPOL J; GOLUB TR; GILLILAND DG; et al.
TEL AND KIP1 DEFINE THE SMALLEST REGION OF DELETIONS ON 12P13 IN HEMATOPOIETIC MALIGNANCIES
0 77
249 5 24 248 1995 SEP [15] NATURE GENETICS 11(1):99-102
PAPADOPOULOS N; LEACH FS; KINZLER KW; VOGELSTEIN B
MONOALLELIC MUTATION ANALYSIS (MAMA) FOR IDENTIFYING GERMLINE MUTATIONS
3 38
250 6 23 241 1995 SEP 20 GENOMICS 29(2):329-334
NICOLAIDES NC; KINZLER KW; VOGELSTEIN B
ANALYSIS OF THE 5'-REGION OF PMS2 REVEALS HETEROGENEOUS TRANSCRIPTS AND A NOVEL OVERLAPPING GENE
3 20
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
251 1 16 257 1995 OCT 20 SCIENCE 270(5235):484-487
VELCULESCU VE; ZHANG L; VOGELSTEIN B; KINZLER KW
SERIAL ANALYSIS OF GENE-EXPRESSION
18 1504
252 7 24 232 1995 NOV 15 CANCER RESEARCH 55(22):5184-5186
RIGGINS GJ; MARKOWITZ S; WILSON JK; VOGELSTEIN B; KINZLER KW
ABSENCE OF SECRETORY PHOSPHOLIPASE A(2) GENE ALTERATIONS IN HUMAN COLORECTAL-CANCER
3 51
253 7 36 233 1995 NOV 15 CANCER RESEARCH 55(22):5187-5190
WALDMAN T; KINZLER KW; VOGELSTEIN B
P21 IS NECESSARY FOR THE P53-MEDIATED G(1) ARREST IN HUMAN CANCER-CELLS
20 566
254 6 20 249 1995 NOV [15] NATURE MEDICINE 1(11):1203-1206
NYSTROMLAHTI M; KRISTO P; NICOLAIDES NC; CHANG SY; AALTONEN LA; et al.
FOUNDING MUTATIONS AND ALU-MEDIATED RECOMBINATION IN HEREDITARY COLON-CANCER
1 147
255 6 23 242 1995 NOV 20 GENOMICS 30(2):195-206
NICOLAIDES NC; CARTER KC; SHELL BK; PAPADOPOULOS N; VOGELSTEIN B; et al.
GENOMIC ORGANIZATION OF THE HUMAN PMS2 GENE FAMILY
2 45
256 2 25 234 1995 DEC 1 CANCER RESEARCH 55(23):5545-5547
MYEROFF LL; PARSONS R; KIM SJ; HEDRICK L; CHO KR; et al.
A TRANSFORMING GROWTH-FACTOR-BETA RECEPTOR-TYPE-II GENE MUTATION COMMON IN COLON AND GASTRIC BUT RARE IN ENDOMETRIAL CANCERS WITH MICROSATELLITE INSTABILITY
2 347
257 9 24 235 1995 DEC 1 CANCER RESEARCH 55(23):5548-5550
PARSONS R; MYEROFF LL; LIU B; WILLSON JKV; MARKOWITZ SD; et al.
MICROSATELLITE INSTABILITY AND MUTATIONS OF THE TRANSFORMING GROWTH-FACTOR-BETA TYPE-II RECEPTOR GENE IN COLORECTAL-CANCER
17 544
258 1 20 269 1996 JAN 4 NATURE 379(6560):19-20
Kinzler KW; Vogelstein B
Life (and death) in a malignant tumour
1 133
259 10 25 259 1996 JAN 15 CANCER RESEARCH 56(2):235-240
Leach FS; Polyak K; Burrell M; Johnson KA; Hill D; et al.
Expression of the human mismatch repair gene hMSH2 in normal and neoplastic tissues
3 107
260 0 0 268 1996 JAN [15] LABORATORY INVESTIGATION 74(1):895-895
Bennett WP; ElDeiry WS; Guinee DG; Caporaso NE; Welsh JA; et al.
p53/p21((waf1/cip1)) expression in human lung cancer
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
261 5 13 267 1996 FEB 1 GENOMICS 31(3):395-397
Nicolaides NC; Palombo F; Kinzler KW; Vogelstein B; Jiricny J
Molecular cloning of the N-terminus of GTBP
1 23
262 16 36 274 1996 FEB [15] NATURE MEDICINE 2(2):169-174
Liu B; Parsons R; Papadopoulos N; Nicolaides NC; Lynch HT; et al.
Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
10 559
263 4 41 275 1996 APR 30 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(9):4192-4196
DaCosta LT; Jen J; He TC; Chan TA; Kinzler KW; et al.
Converting cancer genes into killer genes
1 32
264 3 28 270 1996 JUN 20 NATURE 381(6584):713-716
Waldman T; Lengauer C; Kinzler KW; Vogelstein B
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
15 482
265 7 37 260 1996 JUL 1 CANCER RESEARCH 56(13):2936-2939
Thiagalingam S; Lisitsyn NA; Hamaguchi M; Wigler MH; Willson JKV; et al.
Evaluation of the FHIT gene in colorectal cancers
1 110
266 10 32 272 1996 JUL [15] NATURE GENETICS 13(3):343-346
Thiagalingam S; Lengauer C; Leach FS; Schutte M; Hahn SA; et al.
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
14 303
267 4 26 273 1996 JUL [15] NATURE GENETICS 13(3):347-349
Riggins GJ; Thiagalingam S; Rozenblum E; Weinstein CL; Kern SE; et al.
Mad-related genes in the human
12 278
268 13 46 276 1996 JUL 23 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(15):7950-7954
Morin PJ; Vogelstein B; Kinzler KW
Apoptosis and APC in colorectal tumorigenesis
9 261
269 7 36 265 1996 AUG 1 GENES & DEVELOPMENT 10(15):1945-1952
Polyak K; Waldman T; He TC; Kinzler KW; Vogelstein B
Genetic determinants of p53-induced apoptosis and growth arrest
8 331
270 5 38 277 1996 AUG 6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(16):8390-8394
Pietenpol JA; Lengauer C; Jordan J; Kinzler KW; Vogelstein B
Mammalian cells resistant to tumor suppressor genes
0 7
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
271 11 40 258 1996 AUG [15] AMERICAN JOURNAL OF PATHOLOGY 149(2):381-387
Polyak K; Hamilton SR; Vogelstein B; Kinzler KW
Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia
1 60
272 6 41 261 1996 AUG [15] CARCINOGENESIS 17(8):1757-1760
BeazerBarclay Y; Levy DB; Moser AR; Dove WF; Hamilton SR; et al.
Sulindac suppresses tumorigenesis in the Min mouse
2 102
273 21 55 278 1996 AUG 20 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(17):9049-9054
Huang J; Papadopoulos N; McKinley AJ; Farrington SM; Curtis LJ; et al.
APC mutations in colorectal tumors with mismatch repair deficiency
11 202
274 0 13 271 1996 AUG 22 NATURE 382(6593):672-672
Kunzler KW; Vogelstein B
Breast cancer - What's mice got to do with it?
0 0
275 9 57 264 1996 OCT [15] CYTOPATHOLOGY 7(5):340-351
Dowell SP; McGoogan E; Picksley SM; ElDeiry WS; Vogelstein B; et al.
Expression of p21(waf1/Cip1), MDM2 and p53 in vivo: Analysis of cytological preparations
0 3
276 27 96 262 1996 OCT 18 CELL 87(2):159-170
Kinzler KW; Vogelstein B
Lessons from hereditary colorectal cancer
28 1767
277 0 2 263 1996 OCT 18 CELL 87(2):173-173
Derynck R; Gelbart WM; Harland RM; Heldin CH; Kern SE; et al.
Nomenclature: Vertebrate mediators of TGF beta family signals
2 97
278 1 1 266 1996 NOV 1 GENES & DEVELOPMENT 10(21):2818-2818
Polyak K; Waldman T; He TC; Kinzler KW; Vogelstein B
Genetic determinants of p53-induced apoptosis and growth arrest (vol 10, pg 1945, 1996)
0 0
279 7 30 284 1997 JAN [15] HUMAN MOLECULAR GENETICS 6(1):105-110
Dunlop MG; Farrington SM; Carothers AD; Wyllie AH; Sharp L; et al.
Cancer risk associated with germline DNA mismatch repair gene mutations
0 168
280 0 0 285 1997 JAN [15] LABORATORY INVESTIGATION 76(1):946-946
Burke L; Freedman A; ElDeiry W; Bennett W; Guinee D; et al.
Cyclin D1, p53 and p21(waf1/cip1) expression predict survival in non-small cell lung cancer (NSCLC).
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
281 2 34 282 1997 JAN 24 CELL 88(2):243-251
Velculescu VE; Zhang L; Zhou W; Vogelstein J; Basrai MA; et al.
Characterization of the yeast transcriptome
7 480
282 8 50 292 1997 MAR 18 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(6):2545-2550
Lengauer C; Kinzler KW; Vogelstein B
DNA methylation and genetic instability in colorectal cancer cells
3 184
283 3 22 293 1997 MAR 21 SCIENCE 275(5307):1784-1787
Korinek V; Barker N; Morin PJ; vanWichen D; deWeger R; et al.
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC(-/-) colon carcinoma
9 1107
284 13 37 294 1997 MAR 21 SCIENCE 275(5307):1787-1790
Morin PJ; Sparks AB; Korinek V; Barker N; Clevers H; et al.
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
12 1342
285 5 29 287 1997 APR 10 NATURE 386(6625):623-627
Lengauer C; Kinzler KW; Vogelstein B
Genetic instability in colorectal cancers
25 588
286 1 20 283 1997 APR [15] CELL DEATH AND DIFFERENTIATION 4(3):242-246
Polyak K; Wu TT; Hamilton SR; Kinzler KW; Vogelstein B
Less death in the dying
0 6
287 1 12 288 1997 APR 24 NATURE 386(6627):761-&
Kinzler KW; Vogelstein B
Cancer-susceptibility genes - Gatekeepers and caretakers
0 447
288 3 34 295 1997 MAY 23 SCIENCE 276(5316):1268-1272
Zhang L; Zhou W; Velculescu VE; Kern SE; Hruban RH; et al.
Gene expression profiles in normal and cancer cells
12 700
289 6 19 281 1997 JUL 1 CANCER RESEARCH 57(13):2578-2580
Riggins GJ; Kinzler KW; Vogelstein B; Thiagalingam S
Frequency of Smad gene mutations in human cancers
8 168
290 5 25 290 1997 SEP [15] NATURE GENETICS 17(1):79-83
Laken SJ; Petersen GM; Gruber SB; Oddoux C; Ostrer H; et al.
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC
2 304
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
291 4 17 291 1997 SEP [15] NATURE MEDICINE 3(9):1034-1036
Waldman T; Zhang YG; Dillehay L; Yu J; Kinzler K; et al.
Cell-cycle arrest versus cell death in cancer therapy
2 212
292 5 29 289 1997 SEP 18 NATURE 389(6648):300-305
Polyak K; Xia Y; Zweier JL; Kinzler KW; Vogelstein B
A model for p53-induced apoptosis
12 1126
293 0 0 279 1997 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 61(4):A36-A36
Velculescu VE; Zhang L; Zhou W; Polyak K; Basrai M; et al.
Serial analysis of gene expression (SAGE).
0 0
294 0 0 280 1997 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 61(4):A89-A89
Zhang L; Zhou W; Velculescu VE; Kern SE; Hruban RH; et al.
Gene expression: a looking glass for cancer
0 0
295 9 38 286 1997 DEC [15] MOLECULAR CELL 1(1):3-11
Hermeking H; Lengauer C; Polyak K; He TC; Zhang L; et al.
14-3-3 sigma is a p53-regulated inhibitor of G2/M progression
11 485
296 4 43 310 1998 JAN 20 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(2):681-686
Chan TA; Morin PJ; Vogelstein B; Kinzler KW
Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis
3 311
297 5 26 297 1998 FEB [15] CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 7(2):109-112
Zhou W; Sokoll LJ; Bruzek DJ; Zhang L; Velculescu VE; et al.
Identifying markers for pancreatic cancer by gene expression analysis
2 50
298 7 56 311 1998 MAR 3 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(5):2412-2416
Zhou SB; Buckhaults P; Zawel L; Bunz F; Riggins G; et al.
Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells
5 68
299 1 25 312 1998 MAR 3 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(5):2509-2514
He TC; Zhou SB; da Costa LT; Yu J; Kinzler KW; et al.
A simplified system for generating recombinant adenoviruses
9 1064
300 11 32 298 1998 MAR 15 CANCER RESEARCH 58(6):1130-1134
Sparks AB; Morin PJ; Vogelstein B; Kinzler KW
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer
10 411
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
301 10 30 301 1998 MAR [15] MOLECULAR AND CELLULAR BIOLOGY 18(3):1635-1641
Nicolaides NC; Littman SJ; Modrich P; Kinzler KW; Vogelstein B
A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype
0 43
302 7 39 304 1998 MAR [15] MOLECULAR CELL 1(4):611-617
Zawel L; Dai JL; Buckhaults P; Zhou SB; Kinzler KW; et al.
Human Smad3 and Smad4 are sequence-specific transcription activators
6 399
303 8 29 306 1998 MAR 19 NATURE 392(6673):300-303
Cahill DP; Lengauer C; Yu J; Riggins GJ; Willson JKV; et al.
Mutations of mitotic checkpoint genes in human cancers
17 613
304 0 0 300 1998 APR 15 GASTROENTEROLOGY 114(4):A651-A651
Nagaba Y; Zhang L; Vogelstein B; Cross H; Guggino S
mRNA expression of L-type calcium channels increases in colon cancer.
0 1
305 1 12 314 1998 MAY 15 SCIENCE 280(5366):1036-1037
Kinzler KW; Vogelstein B
Landscaping the cancer terrain
1 189
306 5 31 313 1998 JUN 9 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(12):6870-6875
Herman JG; Umar A; Polyak K; Graff JR; Ahuja N; et al.
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
2 619
307 8 36 305 1998 JUL [15] MOLECULAR CELL 2(1):121-127
Zhou S; Zawel L; Lengauer C; Kinzler KW; Vogelstein B
Characterization of human FAST-1, a TGF beta and activin signal transducer
0 135
308 10 40 315 1998 SEP 4 SCIENCE 281(5382):1509-1512
He TC; Sparks AB; Rago C; Hermeking H; Zawel L; et al.
Identification of c-MYC as a target of the APC pathway
11 1184
309 15 120 296 1998 OCT [15] AMERICAN JOURNAL OF PATHOLOGY 153(4):1063-1078
Fujiwara T; Stolker JM; Watanabe T; Rashid A; Longo P; et al.
Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences
0 90
310 0 0 302 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9:41A-41A
Cahill DP; Kinzler KW; Vogelstein B; Lengauer C
Mitotic checkpoint genes and chromosomal instability in cancer
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
311 0 0 303 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9:381A-381A
He TC; Kinzler KW; Vogelstein B
Identification of downstream targets in APC/beta-catenin-Tcf4 pathway
0 0
312 3 32 309 1998 NOV [15] NATURE GENETICS 20(3):291-293
Polyak K; Li YB; Zhu H; Lengauer C; Willson JKV; et al.
Somatic mutations of the mitochondrial genome in human colorectal tumours
0 208
313 8 48 316 1998 NOV 20 SCIENCE 282(5393):1497-1501
Bunz F; Dutriaux A; Lengauer C; Waldman T; Zhou S; et al.
Requirement for p53 and p21 to sustain G(2) arrest after DNA damage
16 670
314 5 25 299 1998 DEC 1 CANCER RESEARCH 58(23):5267-5270
Gruber SB; Entius MM; Petersen GM; Laken SJ; Longo PA; et al.
Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome
0 58
315 4 27 308 1998 DEC [15] NATURE BIOTECHNOLOGY 16(13):1352-1356
Laken SJ; Jackson PE; Kinzler KW; Vogelstein B; Strickland PT; et al.
Genotyping by mass spectrometric analysis of short DNA fragments
3 67
316 11 92 307 1998 DEC 17 NATURE 396(6712):643-649
Lengauer C; Kinzler KW; Vogelstein B
Genetic instabilities in human cancers
16 1139
317 0 0 317 1999 JAN [15] BIOPHYSICAL JOURNAL 76(1):A135-A135
Vogelstein B
Genetic instabilities in human cancers
0 0
318 6 29 318 1999 JAN 15 CANCER RESEARCH 59(2):320-324
Grady WM; Myeroff LL; Swinler SE; Rajput A; Thiagalingam S; et al.
Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers
4 117
319 1 13 321 1999 JAN [15] GASTROENTEROLOGY 116(1):210-212
Gruber SB; Petersen GM; Kinzler KW; Vogelstein B
Cancer, crash sites, and the new genetics of neoplasia
0 11
320 0 0 324 1999 JAN [15] JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS 188(1):74-79
Vogelstein B
Familial colon cancer
0 2
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
321 10 41 330 1999 MAR 2 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(5):2322-2326
Laken SJ; Papadopoulos N; Petersen GM; Gruber SB; Hamilton SR; et al.
Analysis of masked mutations in familial adenomatous polyposis
1 49
322 3 35 322 1999 JUN 1 GENOMICS 58(2):181-187
Cahill DP; da Costa LT; Carson-Walter EB; Kinzler KW; Vogelstein B; et al.
Characterization of MAD2B and other mitotic spindle checkpoint genes
0 80
323 7 56 331 1999 AUG 3 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(16):9236-9241
Vogelstein B; Kinzler KW
Digital PCR
6 57
324 6 33 323 1999 AUG [15] JOURNAL OF CLINICAL INVESTIGATION 104(3):263-269
Bunz F; Hwang PM; Torrance C; Waldman T; Zhang YG; et al.
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
7 299
325 12 27 329 1999 SEP 2 ONCOGENE 18(35):5010-5014
da Costa LT; He TC; Yu J; Sparks AB; Morin PJ; et al.
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling
1 46
326 5 20 326 1999 OCT 7 NATURE 401(6753):616-620
Chan TA; Hermeking H; Lengauer C; Kinzler KW; Vogelstein B
14-3-3 sigma is required to prevent mitotic catastrophe after DNA damage
9 324
327 2 8 328 1999 OCT 7 NEW ENGLAND JOURNAL OF MEDICINE 341(15):1144-1146
Zhou SB; Kinzler KW; Vogelstein B
Going mad with Smads
0 16
328 9 61 320 1999 OCT 29 CELL 99(3):335-345
He TC; Chan TA; Vogelstein B; Kinzler KW
PPAR delta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
4 446
329 7 20 319 1999 NOV 1 CANCER RESEARCH 59(21):5403-5407
Lal A; Lash AE; Altschul SF; Velculescu V; Zhang L; et al.
A public database for gene expression in human cancers
3 172
330 0 0 325 1999 NOV [15] MOLECULAR BIOLOGY OF THE CELL 10:351A-351A
Vogelstein B; Kinzler KW
Gatekeepers and caretakers
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
331 9 31 332 1999 DEC 7 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(25):14517-14522
Yu J; Zhang L; Hwang PM; Rago C; Kinzler KW; et al.
Identification and classification of p53-regulated genes
6 198
332 6 11 327 1999 DEC [15] NATURE GENETICS 23(4):387-388
Velculescu VE; Madden SL; Zhang L; Lash AE; Yu J; et al.
Analysis of human transcriptomes
6 224
333 14 46 334 1999 DEC [15] TRENDS IN BIOCHEMICAL SCIENCES 24(12):M57-M60
Cahill DP; Kinzler KW; Vogelstein B; Lengauer C
Genetic instability and darwinian selection in tumours
0 5
334 15 47 335 1999 DEC [15] TRENDS IN CELL BIOLOGY 9(12):M57-M60
Cahill DP; Kinzler KW; Vogelstein B; Lengauer C
Genetic instability and darwinian selection in tumours (Reprinted from Trends in Biochemical Science, vol 12, Dec., 1999)
0 70
335 15 47 336 1999 DEC [15] TRENDS IN GENETICS 15(12):M57-M60
Cahill DP; Kinzler KW; Vogelstein B; Lengauer C
Genetic instability and darwinian selection in tumours (Reprinted from Trends in Biochemical Sciences, vol 12, Dec., 1999)
0 4
336 0 0 333 1999 DEC 17 SCIENCE 286(5448):2300-2301
Vogelstein JT; Vogelstein JV; Vogelstein B
Testing the effects of genetic variations using MINIME technology.
0 0
337 3 15 340 2000 FEB 17 NATURE 403(6771):723-724
Yan H; Papadopoulos N; Marra G; Perrera C; Jiricny J; et al.
Conversion of diploidy to haploidy - Individuals susceptible to multigene disorders may now be spotted more easily.
5 108
338 4 40 345 2000 FEB 29 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(5):2229-2234
Hermeking H; Rago C; Schuhmacher M; Li Q; Barrett JF; et al.
Identification of CDK4 as a target of c-MYC
0 115
339 10 42 338 2000 MAR 15 CANCER RESEARCH 60(6):1671-1676
Shih IM; Tu J; He TC; Vogelstein B; Kinzler KW
The beta-catenin binding domain of adenomatous polyposis coil is sufficient for tumor suppression
1 57
340 4 30 341 2000 APR 27 NATURE 404(6781):1003-1007
Rhee I; Jair KW; Yen RWC; Lengauer C; Herman JG; et al.
CpG methylation is maintained in human cancer cells lacking DNMT1
3 93
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
341 0 25 343 2000 JUN [15] NATURE MEDICINE 6(6):711-714
Shih IM; Torrance C; Sokoll LJ; Chan DW; Kinzler KW; et al.
Assessing tumors in living animals through measurement of urinary beta-human chorionic gonadotropin
0 8
342 14 31 339 2000 JUL 1 GENES & DEVELOPMENT 14(13):1584-1588
Chan TA; Hwang PM; Hermeking H; Kinzler KW; Vogelstein B
Cooperative effects of genes controlling the G(2)/M checkpoint
3 101
343 7 37 337 2000 AUG 1 CANCER LETTERS 156(1):63-72
Flatt PM; Polyak K; Tang LJ; Scatena CD; Westfall MD; et al.
p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest
0 21
344 3 32 346 2000 AUG 18 SCIENCE 289(5482):1197-1202
St Croix B; Rago C; Velculescu V; Traverso G; Romans KE; et al.
Genes expressed in human tumor endothelium
7 425
345 5 50 344 2000 SEP [15] NATURE MEDICINE 6(9):1024-1028
Torrance CJ; Jackson PE; Montgomery E; Kinzler KW; Vogelstein B; et al.
Combinatorial chemoprevention of intestinal neoplasia
0 176
346 2 20 347 2000 SEP 15 SCIENCE 289(5486):1890-1892
Yen H; Kinzler KW; Vogelstein B
Genetics - Genetic testing - Present and future
0 1
347 9 27 349 2000 OCT [15] TRENDS IN GENETICS 16(10):423-425
Velculescu VE; Vogelstein B; Kinzler KW
Analysing uncharted transcriptomes with SAGE
1 83
348 4 23 348 2000 NOV 3 SCIENCE 290(5493):989-+
Zhang L; Yu J; Park BH; Kinzler KW; Vogelstein B
Role of BAX in the apoptotic response to anticancer agents
3 236
349 2 41 342 2000 NOV 16 NATURE 408(6810):307-310
Vogelstein B; Lane D; Levine AJ
Surfing the p53 network
10 844
350 3 18 352 2001 JAN 1 CANCER RESEARCH 61(1):33-35
Jackson PE; Qian GS; Friesen MD; Zhu YR; Lu PX; et al.
Specific p53 mutations detected in plasma and tumors of hepatocellular carcinoma patients by electrospray ionization mass spectrometry
0 22
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
351 7 42 353 2001 JAN 1 CANCER RESEARCH 61(1):256-260
Fink SP; Swinler SE; Lutterbaugh JD; Massague J; Thiagalingam S; et al.
Transforming growth factor-beta-induced growth inhibition in a smad4 mutant colon adenoma cell line
1 33
352 4 20 364 2001 JAN [15] NATURE BIOTECHNOLOGY 19(1):78-81
Zhou W; Galizia G; Goodman SN; Romans KE; Kinzler KW; et al.
Counting alleles reveals a connection between chromosome 18q loss and vascular invasion
4 21
353 10 39 354 2001 FEB 1 CANCER RESEARCH 61(3):818-822
Shih IM; Zhou W; Goodman SN; Lengauer C; Kinzler KW; et al.
Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis
8 107
354 9 27 369 2001 FEB 27 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2598-2603
Park BH; Vogelstein B; Kinzler KW
Genetic disruption of PPAR delta decreases the tumorigenicity of human colon cancer cells
1 69
355 6 27 370 2001 FEB 27 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2640-2645
Shih LM; Wang TL; Traverso G; Romans K; Hamilton SR; et al.
Top-down morphogenesis of colorectal tumors
0 22
356 8 51 371 2001 FEB 27 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2698-2702
Thiagalingam S; Laken S; Willson JKV; Markowitz SD; Kinzler KW; et al.
Mechanisms underlying losses of heterozygosity in human colorectal cancers
5 66
357 2 29 351 2001 MAR [15] CALCIFIED TISSUE INTERNATIONAL 68(3):151-155
Sparks AB; Peterson SN; Bell C; Loftus BJ; Hocking L; et al.
Mutation screening of the TNFRSF11A gene encoding receptor activator of NF kappa B (RANK) in familial and sporadic Paget's disease of bone and osteosarcoma
0 19
358 16 54 362 2001 MAR [15] MOLECULAR CELL 7(3):673-682
Yu J; Zhang L; Hwang PM; Kinzler KW; Vogelstein B
PUMA induces the rapid apoptosis of colorectal cancer cells
3 240
359 11 33 355 2001 MAY 1 CANCER RESEARCH 61(9):3801-3805
Zhang L; Yu J; Willson JKV; Markowitz SD; Kinzler KW; et al.
Short mononucleotide repeat sequence variability in mismatch repair-deficient cancers
1 27
360 8 35 372 2001 MAY 8 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(10):5770-5775
Bardelli A; Cahill CP; Lederer G; Speicher MR; Kinzler KW; et al.
Carcinogen-specific induction of genetic instability
3 56
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
361 8 52 360 2001 MAY 18 CELL 105(4):445-457
Jallepalli PV; Waizenegger IC; Bunz F; Langer S; Speicher MR; et al.
Securin is required for chromosomal stability in human cells
10 110
362 7 31 361 2001 JUN 6 JOURNAL OF THE NATIONAL CANCER INSTITUTE 93(11):858-865
Dong SM; Traverso G; Johnson C; Geng L; Favis R; et al.
Detecting colorectal cancer in stool with the use of multiple genetic targets
2 97
363 2 30 366 2001 JUN [15] NATURE GENETICS 28(2):184-187
Howe JR; Bair JL; Sayed MG; Anderson ME; Mitros FA; et al.
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
1 81
364 5 17 363 2001 AUG 30 NATURE 412(6850):865-866
Vogelstein B; Kinzler KW
Achilles' heel of cancer?
0 21
365 1 35 356 2001 SEP 15 CANCER RESEARCH 61(18):6649-6655
Carson-Walter EB; Watkins DN; Nanda A; Vogelstein B; Kinzler KW; et al.
Cell surface tumor endothelial markers are conserved in mice and humans
2 66
366 5 23 357 2001 OCT 1 CANCER RESEARCH 61(19):6996-7001
Buckhaults P; Rago C; St Croix B; Romans KE; Saha S; et al.
Secreted and cell surface genes expressed in benign and malignant colorectal tumors
4 41
367 0 0 350 2001 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 69(4):257-257
Wiesner GL; Daley D; Platzer P; Yan H; Ticknor C; et al.
Common colon neoplasia is not linked to germline APC variants.
0 0
368 0 17 365 2001 OCT [15] NATURE BIOTECHNOLOGY 19(10):940-945
Torrance CJ; Agrawal V; Vogelstein B; Kinzler KW
Use of isogenic human cancer cells for high-throughput screening and drug discovery
1 47
369 15 39 367 2001 OCT [15] NATURE MEDICINE 7(10):1111-1117
Hwang PM; Bunz F; Yu J; Rago C; Chan TA; et al.
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells
3 59
370 0 0 375 2001 OCT 15 SCIENTIST 15(20):6-6
Vogelstein B
The science behind stem cell research
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
371 2 15 358 2001 NOV 1 CANCER RESEARCH 61(21):7719-7721
Marra G; D'Atri S; Yan H; Perrera C; Cannavo E; et al.
Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes
0 6
372 7 44 359 2001 NOV 1 CANCER RESEARCH 61(21):7798-7802
Liu T; Yan H; Kuismanen S; Percesepe A; Bisgaard ML; et al.
The role of hPMS1 and hPMS2 in predisposing to colorectal cancer
0 34
373 6 24 374 2001 NOV 9 SCIENCE 294(5545):1343-1346
Saha S; Bardelli A; Buckhaults P; Velculescu VE; Rago C; et al.
A phosphatase associated with metastasis of colorectal cancer
3 96
374 1 1 368 2001 NOV [15] NATURE MEDICINE 7(11):1255-1255
Hwang PM; Bunz F; Yu J; Rago C; Chan TA; et al.
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells (vol 7, pg 1111, 2001)
0 0
375 0 36 373 2001 DEC 18 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(26):15155-15160
Dang LH; Bettegowda C; Huso DL; Kinzler KW; Vogelstein B
Combination bacteriolytic therapy for the treatment of experimental tumors
3 39
376 0 0 376 2002 JAN [15] ANNALS OF SURGICAL ONCOLOGY 9(1):S8-S9
Sayed MG; Ahmed AF; Anderson ME; Bair JL; Mitros FA; et al.
The impact of germline SMAD4 or BMPR1A mutations on the phenotype of juvenile polyposis
0 0
377 5 10 387 2002 JAN [15] NATURE GENETICS 30(1):25-26
Yan H; Dobbie Z; Gruber SB; Markowitz S; Romans K; et al.
Small changes in expression affect predisposition to tumorigenesis
2 59
378 7 30 382 2002 JAN 19 LANCET 359(9302):219-225
Zhou W; Goodman SN; Galizia G; Lieto E; Ferraraccio F; et al.
Counting alleles to predict recurrence of early-stage colorectal cancers
0 38
379 6 47 388 2002 JAN 31 NEW ENGLAND JOURNAL OF MEDICINE 346(5):311-320
Traverso G; Shuber A; Levin B; Johnson C; Olsson L; et al.
Detection of APC mutations in fecal DNA from patients with colorectal tumors
2 92
380 1 5 383 2002 FEB 2 LANCET 359(9304):403-404
Traverso G; Shuber A; Olsson L; Levin B; Johnson C; et al.
Detection of proximal colorectal cancers through analysis of faecal DNA
1 43
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
381 7 29 379 2002 FEB 15 CANCER RESEARCH 62(4):1129-1133
Bunz F; Fauth C; Speicher MR; Dutriaux A; Sedivy JM; et al.
Targeted inactivation of p53 in human cells does not result in aneuploidy
1 42
382 0 3 395 2002 FEB 15 SCIENCE 295(5558):1237-1237
Vogelstein B; Alberts B; Shine K
Genetics - Please don't call it cloning!
0 20
383 11 43 390 2002 MAR 5 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(5):2848-2853
Zawel L; Yu J; Torrance CJ; Markowitz S; Kinzler KW; et al.
DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities
0 26
384 6 32 391 2002 MAR 5 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(5):3076-3080
Wang TL; Rago C; Silliman N; Ptak J; Markowitz S; et al.
Prevalence of somatic alterations in the colorectal cancer cell genome
5 41
385 2 30 384 2002 APR 4 NATURE 416(6880):552-556
Rhee I; Bachman KE; Park BH; Jair KW; Yen RWC; et al.
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
1 131
386 4 19 386 2002 MAY [15] NATURE BIOTECHNOLOGY 20(5):508-512
Saha S; Sparks AB; Rago C; Akmaev V; Wang CJ; et al.
Using the transcriptome to annotate the genome
1 107
387 12 53 392 2002 JUN 11 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(12):8265-8270
Chan TA; Wang ZH; Dang LH; Vogelstein B; Kinzler KW
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
1 25
388 0 4 389 2002 JUN 13 NEW ENGLAND JOURNAL OF MEDICINE 346(24):1912-1913
Traverso G; Kinzler KW; Vogelstein B
Fecal DNA tests for colorectal cancer - Reply
0 0
389 0 0 396 2002 JUL 5 SCIENCE 297(5578):52-52
Vogelstein B; Alberts B; Shine K
Calling it something other than cloning - Response
0 0
390 1 17 380 2002 AUG 15 CANCER RESEARCH 62(16):4579-4582
Nakagawa H; Yan H; Lockman J; Hampel H; Kinzler KW; et al.
Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements
0 16
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
391 1 4 397 2002 AUG 16 SCIENCE 297(5584):1143-1143
Yan H; Yuan WS; Velculescu VE; Vogelstein B; Kinzler KW
Allelic variation in human gene expression
1 116
392 4 9 385 2002 AUG 29 NATURE 418(6901):934-934
Rajagopalan H; Bardelli A; Lengauer C; Kinzler KW; Vogelstein B; et al.
Tumorigenesis - RAF/RAS oncogenes and mismatch-repair status
3 117
393 1 38 377 2002 NOV [15] ANNALS OF SURGICAL ONCOLOGY 9(9):901-906
Sayed MG; Ahmed AF; Ringold JR; Anderson ME; Bair JL; et al.
Germline SMAD4 or BMPR1A mutations and phenotype of juvenile polyposis
0 16
394 5 31 378 2002 NOV-DEC [NOV 15] CANCER BIOLOGY & THERAPY 1(6):685-692
Komarova NL; Lengauer C; Vogelstein B; Nowak MA
Dynamics of genetic instability in sporadic and familial colorectal cancer
0 12
395 0 0 381 2002 NOV [15] EUROPEAN JOURNAL OF CANCER 38:S126-S126
Hallur Gurulingappa H; Buckhaults P; Kinzler KW; Vogelstein B; Khan SR
Synthesis and evaluation of renal dipeptidase inhibitors as biomarkers for colon cancer
0 0
396 4 27 393 2002 DEC 10 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(25):16156-16161
Wang TL; Maierhofer C; Speicher MR; Lengauer C; Vogelstein B; et al.
Digital karyotyping
2 19
397 6 36 394 2002 DEC 10 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(25):16226-16231
Nowak MA; Komarova NL; Sengupta A; Jallepalli PV; Shih IM; et al.
The role of chromosomal instability in tumor initiation
3 63
398 3 3 407 2003 JAN 1 JOURNAL OF THE NATIONAL CANCER INSTITUTE 95(1):73-73
Jen J; Vogelstein B
Tumor location and detection of K-Ras mutations in stool from colorectal cancer patients - Response
0 0
399 2 25 398 2003 JAN [15] CANCER CELL 3(1):89-95
Bachman KE; Park BH; Rhee I; Rajagopalan H; Herman JG; et al.
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene
0 55
400 12 47 410 2003 FEB 18 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(4):1931-1936
Yu J; Wang ZH; Kinzler KW; Vogelstein B; Zhang L
PUMA mediates the apoptotic response to p53 in colorectal cancer cells
1 67
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
401 1 14 414 2003 FEB 24 TETRAHEDRON LETTERS 44(9):1871-1873
Gurulingappa H; Buckhaults P; Kumar SK; Kinzler KW; Vogelstein B; et al.
Design, synthesis and evaluation of new RDP inhibitors
1 3
402 7 50 399 2003 MAR 1 CANCER RESEARCH 63(5):994-999
Hempen PM; Zhang L; Bansal RK; Iacobuzio-Donahue CA; Murphy KM; et al.
Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers
0 11
403 0 3 413 2003 MAY 9 SCIENCE 300(5621):949-949
Bardelli A; Parsons DW; Silliman N; Ptak J; Szabo S; et al.
Mutational analysis of the tyrosine kinome in colorectal cancers
3 41
404 10 44 406 2003 JUN 6 JOURNAL OF BIOLOGICAL CHEMISTRY 278(23):20475-20479
Jallepalli PV; Lengauer C; Vogelstein B; Bunz F
The Chk2 tumor suppressor is not required for p53 responses in human cancer cells
0 34
405 0 0 404 2003 JUN [15] DIABETES 52:A256-A256
Tsuchiya T; Yan H; Vogelstein B; Kinzler K; Bell G
Identification of a haplotype associated with the decreased expression of calpain-10 in lymphoblastoid cell lines
0 0
406 2 34 402 2003 JUL [15] CLINICAL CANCER RESEARCH 9(7):2642-2650
Brown DA; Ward RL; Buckhaults P; Liu T; Romans KE; et al.
MIC-1 serum level and genotype: Associations with progress and prognosis of colorectal carcinoma
1 3
407 5 29 411 2003 JUL 22 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(15):8817-8822
Dressman D; Yan H; Traverso G; Kinzler KW; Vogelstein B
Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations
0 10
408 1 11 400 2003 SEP 1 CANCER RESEARCH 63(17):5234-5235
Wang ZH; Vogelstein B; Kinzler KW
Phosphorylation of beta-catenin at S33, S37, or T41 can occur in the absence of phosphorylation at T45 in colon cancer cells
0 3
409 3 13 408 2003 SEP [15] NATURE BIOTECHNOLOGY 21(9):1093-1097
Traverso G; Diehl F; Hurst R; Shuber A; Whitney D; et al.
Multicolor in vitro translation
0 3
410 14 59 409 2003 SEP [15] NATURE REVIEWS CANCER 3(9):695-701
Rajagopalan H; Nowak MA; Vogelstein B; Lengauer C
The significance of unstable chromosomes in colorectal cancer
3 47
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
411 6 22 403 2003 NOV 15 CLINICAL CANCER RESEARCH 9(15):5607-5615
Bardelli A; Saha S; Sager JA; Romans KE; Xin BZ; et al.
PRL-3 expression in metastatic cancers
1 7
412 1 17 412 2003 DEC 9 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(25):15083-15088
Bettegowda C; Dang LH; Abrams R; Huson DL; Dillehay L; et al.
Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria
1 2
413 6 27 401 2003 DEC 15 CANCER RESEARCH 63(24):8578-8581
Traverso G; Bettegowda C; Kraus J; Speicher MR; Kinzler KW; et al.
Hyper-recombination and genetic instability in BLM-deficient epithelial cells
0 3
414 1 1 405 2003 DEC [15] GENES CHROMOSOMES & CANCER 38(4):329-329
Baker SJ; Kinzler KW; Vogelstein B
Knudson's hypothesis and the TP53 revolution
0 1
415 3 20 427 2004 JAN [15] NUCLEIC ACIDS RESEARCH 32(1)
Kohli M; Rago C; Lengauer C; Kinzler KW; Vogelstein B
Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses
0 2
416 2 14 416 2004 FEB 1 CANCER RESEARCH 64(3):817-820
Nanda A; Carson-Walter EB; Seaman S; Barber TD; Stampfl J; et al.
TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI)
1 5
417 6 41 429 2004 MAR 2 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(9):3089-3094
Wang TL; Diaz LA; Romans K; Bardelli A; Saha S; et al.
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients
0 6
418 9 28 423 2004 MAR 4 NATURE 428(6978):77-81
Rajagopalan H; Jallepalli PV; Rago C; Velculescu VE; Kinzler KW; et al.
Inactivation of hCDC4 can cause chromosomal instability
1 29
419 4 43 422 2004 APR 1 CLINICAL CANCER RESEARCH 10(7):2386-2392
Koopmann J; Buckhaults P; Brown DA; Zahurak ML; Sato N; et al.
Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers
0 1
420 2 13 424 2004 APR 1 NATURE 428(6982)
Cummins JM; Rago C; Kohli M; Kinzler KW; Lengauer C; et al.
Disruption of HAUSP gene stabilizes p53
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
421 0 0 428 2004 APR [15] PEDIATRIC RESEARCH 55(4):270A-271A
Parsons DW; Bardelli A; Wang TL; Kinzler KW; Vogelstein B; et al.
Mutational analysis of the protein kinome in colorectal cancer
0 0
422 1 4 432 2004 APR 23 SCIENCE 304(5670):554-554
Samuels Y; Wang ZH; Bardelli A; Silliman N; Ptak J; et al.
High frequency of mutations of the PIK3CA gene in human cancers
0 33
423 5 30 417 2004 MAY 1 CANCER RESEARCH 64(9):2998-3001
Wang ZH; Cummins JM; Shen D; Cahill DP; Jallepalli PV; et al.
Three classes of genes mutated in colorectal cancers with chromosomal instability
0 6
424 0 14 418 2004 MAY 1 CANCER RESEARCH 64(9):3006-3008
Cummins JM; Kohli M; Rago C; Kinzler KW; Vogelstein B; et al.
X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells
1 5
425 5 28 433 2004 MAY 21 SCIENCE 304(5674):1164-1166
Wang ZH; Shen D; Parsons DW; Bardelli A; Sager J; et al.
Mutational analysis of the tyrosine phosphatome in colorectal cancers
0 9
426 2 19 421 2004 JUN [15] CELL CYCLE 3(6):689-692
Cummins JM; Vogelstein B
HAUSP is required for p53 destabilization
0 0
427 2 18 415 2004 JUL 5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14(13):3531-3533
Gurulingappa H; Buckhalts P; Kinzler KW; Vogelstein B; Khan SR
Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase
0 0
428 7 118 425 2004 AUG [15] NATURE MEDICINE 10(8):789-799
Vogelstein B; Kinzler KW
Cancer genes and the pathways they control
1 20
429 3 32 430 2004 OCT 19 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(42):15172-15177
Agrawal N; Bettegowda C; Cheong I; Geschwind JF; Drake CG; et al.
Bacteriolytic therapy can generate a potent immune response against experimental tumors
1 1
430 5 37 431 2004 NOV 30 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(48):16897-16902
Kohli M; Yu J; Seaman C; Bardelli A; Kinzler KW; et al.
SMAC/Diablo-dependent apoptosis induced by nonsteroidal anti inflammatory drugs (NSAIDs) in colon cancer cells
0 0
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
431 3 9 419 2004 DEC 1 CANCER RESEARCH 64(23):8507-8511
Nanda A; Buckhaults P; Seaman S; Agrawal N; Boutin P; et al.
Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R
0 0
432 2 20 420 2004 DEC 15 CANCER RESEARCH 64(24):8816-8820
Bentires-Alj M; Paez JG; David FS; Keilhack H; Halmos B; et al.
Activating mutations of the Noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia
0 1
433 0 5 426 2004 DEC 30 NEW ENGLAND JOURNAL OF MEDICINE 351(27):2883-2883
Barber TD; Vogelstein B; Kinzler KW; Velculescu VE
Somatic mutations of EGFR in colorectal cancers and glioblastomas
0 0
434 2 28 434 2005 JAN 25 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(4):1145-1150
Bettegowda C; Foss CA; Cheong I; Wang YC; Diaz L; et al.
Imaging bacterial infections with radiolabeled 1-(2 '-deoxy-2 '-fluoro-beta-D-arabinofuranosyl)-5-iodouracil
0 0
435 7 58 435 2005 FEB [15] SEMINARS IN CANCER BIOLOGY 15(1):43-49
Michor F; Iwasa Y; Vogelstein B; Lengauer C; Nowak MA
Can chromosomal instability initiate tumorigenesis?
0 0

#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
1	0	40	1 1976 [JUN 30] NEW ENGLAND JOURNAL OF MEDICINE 295(12):655-658 PRYSTOWSKY SD; VOGELSTEIN B; ETTINGER DS; MERZ WG; KAIZER H; et al. INVASIVE ASPERGILLOSIS	0	105
2	0	0	2 1976 [JUN 30] PEDIATRIC RESEARCH 10(4):456-456 MOXON ER; VOGELSTEIN B; RILEY RL; MERZ WG; DOBSON ML; et al. CUTANEOUS ASPERGILLUS INFECTION IN COMPROMISED HOSTS - CLINICAL AND EPIDEMIOLOGIC FEATURES	0	0
3	0	23	3 1976 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73(10):3671-3675 DINTZIS HM; DINTZIS RZ; VOGELSTEIN B MOLECULAR DETERMINANTS OF IMMUNOGENICITY - IMMUNON MODEL OF IMMUNE-RESPONSE	2	157
4	0	9	4 1977 [JUN 30] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 75(4):1127-1132 VOGELSTEIN B; GILLESPIE D RNA-DNA HYBRIDIZATION IN SOLUTION WITHOUT DNA RE-ANNEALING	4	26
5	0	26	5 1977 [JUN 30] CLINICAL PHARMACOLOGY & THERAPEUTICS 22(2):131-139 VOGELSTEIN B; KOWARSKI AA; LIETMAN PS CONTINUOUS SAMPLING AS A PHARMACOKINETIC TOOL	0	19
6	0	36	6 1977 [JUN 30] JOURNAL OF PEDIATRICS 91(2):333-339 VOGELSTEIN B; AVINOAMKOWARSKI A; LIETMAN PS PHARMACOKINETICS OF AMIKACIN IN CHILDREN	0	53
7	1	19	7 1979 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 76(2):615-619 VOGELSTEIN B; GILLESPIE D PREPARATIVE AND ANALYTICAL PURIFICATION OF DNA FROM AGAROSE	7	1201
8	0	45	8 1980 [JUN 30] CELL 19(2):527-536 PARDOLL DM; VOGELSTEIN B; COFFEY DS FIXED SITE OF DNA-REPLICATION IN EUKARYOTIC CELLS	9	581
9	1	44	9 1980 [JUN 30] CELL 22(1):79-85 VOGELSTEIN B; PARDOLL DM; COFFEY DS SUPERCOILED LOOPS AND EUKARYOTIC DNA-REPLICATION	11	511
10	2	23	10 1980 [JUN 30] EXPERIMENTAL CELL RESEARCH 128(2):466-470 PARDOLL DM; VOGELSTEIN B SEQUENCE-ANALYSIS OF NUCLEAR MATRIX ASSOCIATED DNA FROM RAT-LIVER	7	78
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
11	0	24	11 1980 [JUN 30] FEBS LETTERS 109(2):233-238 NELKIN B; NICHOLS C; VOGELSTEIN B PROTEIN FACTOR(S) FROM MITOTIC CHO CELLS INDUCE MEIOTIC MATURATION IN XENOPUS-LAEVIS OOCYTES	1	91
12	2	32	12 1980 [JUN 30] GENE 11(1-2):89-96 NELKIN B; STRAYER D; VOGELSTEIN B DIVERGENCE OF PRIMATE RIBOSOMAL-RNA GENES AS ASSAYED BY RESTRICTION ENZYME ANALYSIS	0	10
13	3	55	13 1980 [JUN 30] NUCLEIC ACIDS RESEARCH 8(23):5623-5633 NELKIN BD; PARDOLL DM; VOGELSTEIN B LOCALIZATION OF SV40-GENES WITHIN SUPERCOILED LOOP DOMAINS	7	101
14	1	18	14 1981 [JUN 30] EXPERIMENTAL CELL RESEARCH 133(2):445-449 ROBINSON SI; NELKIN B; KAUFMANN S; VOGELSTEIN B INCREASED PHOSPHORYLATION RATE OF INTERMEDIATE FILAMENTS DURING MITOTIC ARREST	0	21
15	2	54	15 1981 [JUN 30] NUCLEIC ACIDS RESEARCH 9(2):349-363 HUNT BF; VOGELSTEIN B ASSOCIATION OF NEWLY REPLICATED DNA WITH THE NUCLEAR MATRIX OF PHYSARUM-POLYCEPHALUM	4	76
16	5	59	16 1982 [JUN 30] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 105(3):1224-1232 VOGELSTEIN B; HUNT BF A SUBSET OF SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE ANTIGENS IS A COMPONENT OF THE NUCLEAR MATRIX	0	44
17	5	75	17 1982 [JUN 30] CELL 28(1):99-106 ROBINSON SI; NELKIN BD; VOGELSTEIN B THE OVALBUMIN GENE IS ASSOCIATED WITH THE NUCLEAR MATRIX OF CHICKEN OVIDUCT CELLS	7	337
18	0	0	18 1982 [JUN 30] FEDERATION PROCEEDINGS 41(4):1461-1461 NELKIN BD; ROBINSON SI; SMALL D; VOGELSTEIN B THE NUCLEAR MATRIX, SUPERCOILED LOOPS AND GENE-EXPRESSION	0	0
19	0	0	19 1982 [JUN 30] JOURNAL OF CELL BIOLOGY 95(2):A76-A76 SMALL D; NELKIN B; GILMOUR D; LIS J; VOGELSTEIN B ASSOCIATION OF TRANSCRIBED GENES WITH THE NUCLEAR MATRIX OF DROSOPHILA CELLS BEFORE AND DURING HEAT-SHOCK	0	4
20	0	0	20 1982 [JUN 30] JOURNAL OF CELL BIOLOGY 95(2):A224-A224 FEINBERG AP; VOGELSTEIN B HYPOMETHYLATION OF SPECIFIC GENES IN SOME HUMAN CANCERS	0	0
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
21	1	22	21 1982 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(2):395-399 VOGELSTEIN B; DINTZIS RZ; DINTZIS HM SPECIFIC CELLULAR-STIMULATION IN THE PRIMARY IMMUNE-RESPONSE - A QUANTIZED MODEL	2	39
22	2	37	22 1982 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(3):884-888 DINTZIS RZ; VOGELSTEIN B; DINTZIS HM SPECIFIC CELLULAR-STIMULATION IN THE PRIMARY IMMUNE-RESPONSE - EXPERIMENTAL TEST OF A QUANTIZED MODEL	0	39
23	4	40	23 1982 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(19):5911-5915 SMALL D; NELKIN B; VOGELSTEIN B NONRANDOM DISTRIBUTION OF REPEATED DNA-SEQUENCES WITH RESPECT TO SUPERCOILED LOOPS AND THE NUCLEAR MATRIX	1	66
24	1	1	24 1982 [JUN 30] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(23):7604-7604 VOGELSTEIN B CORRECTION	0	0
25	0	0	25 1982 [JUN 30] RADIATION RESEARCH 91(2):403-403 VOGELSTEIN B SUPERCOILED LOOPS AND DNA ORGANIZATION	0	0
26	6	85	26 1982 [JUN 30] UCLA SYMPOSIA ON MOLECULAR AND CELLULAR BIOLOGY 26:105-119 VOGELSTEIN B; NELKIN B; PARDOLL D; ROBINSON S; SMALL D SUPERCOILED LOOPS AND TRANSCRIBING GENES	0	2
27	0	33	27 1983 [JUN 30] ANALYTICAL BIOCHEMISTRY 132(1):6-13 FEINBERG AP; VOGELSTEIN B A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY	21	20884
28	1	46	28 1983 [JUN 30] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 111(1):47-54 FEINBERG AP; VOGELSTEIN B HYPOMETHYLATION OF RAS ONCOGENES IN PRIMARY HUMAN CANCERS	4	229
29	0	57	29 1983 [JUN 30] NATURE 301(5895):89-92 FEINBERG AP; VOGELSTEIN B HYPOMETHYLATION DISTINGUISHES GENES OF SOME HUMAN CANCERS FROM THEIR NORMAL COUNTERPARTS	7	486
30	5	40	30 1983 [JUN 30] NUCLEIC ACIDS RESEARCH 11(15):5113-5130 ROBINSON SI; SMALL D; IDZERDA R; MCKNIGHT GS; VOGELSTEIN B THE ASSOCIATION OF TRANSCRIPTIONALLY ACTIVE GENES WITH THE NUCLEAR MATRIX OF THE CHICKEN OVIDUCT	3	133
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
31	2	47	31 1983 [JUN 30] SCIENCE 220(4602):1175-1177 FEINBERG AP; VOGELSTEIN B; DROLLER MJ; BAYLIN SB; NELKIN BD MUTATION AFFECTING THE 12TH AMINO-ACID OF THE C-HA-RAS ONCOGENE PRODUCT OCCURS INFREQUENTLY IN HUMAN CANCER	3	131
32	0	0	32 1984 [JUN 30] JOURNAL OF CELL BIOLOGY 99(4):A128-A128 HALLIGAN BD; SMALL D; VOGELSTEIN B; HSIEH TS; LIU LF LOCALIZATION OF TYPE-II DNA TOPOISOMERASE IN NUCLEAR MATRIX	0	15
33	1	40	33 1984 [JUN 30] NATURE 309(5964):176-178 FEARON ER; VOGELSTEIN B; FEINBERG AP SOMATIC DELETION AND DUPLICATION OF GENES ON CHROMOSOME-11 IN WILMS-TUMORS	6	447
34	2	22	34 1985 [JUN 30] BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 130(1):118-126 GOELZ SE; HAMILTON SR; VOGELSTEIN B PURIFICATION OF DNA FROM FORMALDEHYDE FIXED AND PARAFFIN EMBEDDED HUMAN-TISSUE	31	697
35	7	33	35 1985 [JUN 30] BIOESSAYS 2(2):52-54 ZEHNBAUER BA; VOGELSTEIN B SUPERCOILED LOOPS AND THE ORGANIZATION OF REPLICATION AND TRANSCRIPTION IN EUKARYOTES	1	59
36	3	36	36 1985 [JUN 30] NATURE 318(6044):377-380 FEARON ER; FEINBERG AP; HAMILTON SH; VOGELSTEIN B LOSS OF GENES ON THE SHORT ARM OF CHROMOSOME-11 IN BLADDER-CANCER	9	371
37	5	59	37 1985 [JUN 30] NUCLEIC ACIDS RESEARCH 13(7):2413-2431 SMALL D; NELKIN B; VOGELSTEIN B THE ASSOCIATION OF TRANSCRIBED GENES WITH THE NUCLEAR MATRIX OF DROSOPHILA CELLS DURING HEAT-SHOCK	1	96
38	7	34	38 1985 [JUN 30] NUCLEIC ACIDS RESEARCH 13(21):7703-7713 SMALL D; VOGELSTEIN B THE ANATOMY OF SUPERCOILED LOOPS IN THE DROSOPHILA-7F LOCUS	0	15
39	0	0	39 1985 [JUN 30] PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 26(MAR):64-64 TRENT J; MELTZER P; ROSENBLUM M; HARSH G; KINZLER K; et al. EVIDENCE FOR REARRANGEMENT AND AMPLIFICATION OF THE C-MYC CELLULAR ONCOGENE IN A HUMAN GLIOBLASTOMA	0	4
40	1	42	40 1985 [JUN 30] SCIENCE 227(4687):642-645 VOGELSTEIN B; FEARON ER; HAMILTON SR; FEINBERG AP USE OF RESTRICTION FRAGMENT LENGTH POLYMORPHISMS TO DETERMINE THE CLONAL ORIGIN OF HUMAN-TUMORS	7	339
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41	3	54	41 1985 [JUN 30] SCIENCE 228(4696):187-190 GOELZ SE; VOGELSTEIN B; HAMILTON SR; FEINBERG AP HYPOMETHYLATION OF DNA FROM BENIGN AND MALIGNANT HUMAN-COLON NEOPLASMS	8	367
42	0	18	43 1986 JAN 1 CANCER GENETICS AND CYTOGENETICS 19(1-2):93-99 MELTZER P; KINZLER K; VOGELSTEIN B; TRENT JM GENE AMPLIFICATION IN CANCER - A MOLECULAR CYTOGENETIC APPROACH	0	15
43	0	25	48 1986 JAN [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(2):470-473 TRENT J; MELTZER P; ROSENBLUM M; HARSH G; KINZLER K; et al. EVIDENCE FOR REARRANGEMENT, AMPLIFICATION, AND EXPRESSION OF C-MYC IN A HUMAN GLIOBLASTOMA	7	134
44	2	41	49 1986 FEB [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(4):1031-1035 KINZLER KW; ZEHNBAUER BA; BRODEUR GM; SEEGER RC; TRENT JM; et al. AMPLIFICATION UNITS CONTAINING HUMAN N-MYC AND C-MYC GENES	5	80
45	1	13	42 1986 MAR [15] BLOOD 67(3):835-838 ZEHNBAUER BA; PARDOLL DM; BURKE PJ; GRAHAM ML; VOGELSTEIN B IMMUNOGLOBULIN GENE REARRANGEMENTS IN REMISSION BONE-MARROW SPECIMENS FROM PATIENTS WITH ACUTE LYMPHOBLASTIC-LEUKEMIA	0	92
46	0	0	44 1986 APR [15] CLINICAL RESEARCH 34(2):A689-A689 BAYLIN SB; FEARON ER; VOGELSTEIN B; DEBUSTROS A; SHARKIS SJ; et al. HYPERMETHYLATION OF THE CALCITONIN GENE - A PROPERTY OF HUMAN SMALL-CELL LUNG-CANCER AND LYMPHO-HEMATOPOIETIC MALIGNANCIES	0	1
47	0	0	45 1986 [JUN 30] JOURNAL OF NEURO-ONCOLOGY 4(1):92-92 BIGNER SH; MARK J; KINZLER KW; VOGELSTEIN B; SCHOLD SC; et al. CHROMOSOMES AND GENE AMPLIFICATION IN MALIGNANT HUMAN GLIOMAS	0	0
48	3	54	46 1986 JUL 3 NEW ENGLAND JOURNAL OF MEDICINE 315(1):15-24 FEARON ER; BURKE PJ; SCHIFFER CA; ZEHNBAUER BA; VOGELSTEIN B DIFFERENTIATION OF LEUKEMIA-CELLS TO POLYMORPHONUCLEAR LEUKOCYTES IN PATIENTS WITH ACUTE NONLYMPHOCYTIC LEUKEMIA	3	300
49	3	50	50 1986 JUL 25 SCIENCE 233(4762):461-464 WONG AJ; RUPPERT JM; EGGLESTON J; HAMILTON SR; BAYLIN SB; et al. GENE AMPLIFICATION OF C-MYC AND N-MYC IN SMALL CELL-CARCINOMA OF THE LUNG	7	255
50	0	2	47 1986 DEC 4 NEW ENGLAND JOURNAL OF MEDICINE 315(23):1488-1488 FEARON ER; BURKE PJ; ZEHNBAUER BA; VOGELSTEIN B; SCHIFFER CA DIFFERENTIATION OF BLAST CELLS IN ACUTE NONLYMPHOCYTIC LEUKEMIA - REPLY	0	2
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51	2	16	51 1987 JAN [15] ANALYTICAL BIOCHEMISTRY 160(1):115-118 VOGELSTEIN B RAPID PURIFICATION OF DNA FROM AGAROSE GELS BY CENTRIFUGATION THROUGH A DISPOSABLE PLASTIC COLUMN	8	25
52	3	32	62 1987 FEB 19 NEW ENGLAND JOURNAL OF MEDICINE 316(8):427-431 FEARON ER; WINKELSTEIN JA; CIVIN CI; PARDOLL DM; VOGELSTEIN B CARRIER DETECTION IN X-LINKED AGAMMAGLOBULINEMIA BY ANALYSIS OF X-CHROMOSOME INACTIVATION	2	136
53	0	0	58 1987 MAR 1 FEDERATION PROCEEDINGS 46(3):973-973 NELKIN BD; FEARON ER; VOGELSTEIN B; DEBUSTROS A; PRZEPIORKA D; et al. INCREASED CALCITONIN GENE DNA METHYLATION IN HUMAN LYMPHOID AND MYELOID MALIGNANCIES	0	0
54	0	0	59 1987 MAR [15] IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY 23(3):A29-A29 VOGELSTEIN B; FEARON ER CLONAL ANALYSIS OF HUMAN-CELLS USING RECOMBINANT-DNA TECHNIQUES	0	0
55	0	0	64 1987 MAR [15] PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 28:23-23 HUMPHREY PA; WONG AJ; FRIEDMAN HS; WERNER MH; VOGELSTEIN B; et al. AMPLIFICATION AND EXPRESSION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR (EGFR) GENE IN HUMAN GLIOMA (HGL) XENOGRAFTS	1	2
56	3	43	66 1987 APR 3 SCIENCE 236(4797):70-73 KINZLER KW; BIGNER SH; BIGNER DD; TRENT JM; LAW ML; et al. IDENTIFICATION OF AN AMPLIFIED, HIGHLY EXPRESSED GENE IN A HUMAN GLIOMA	15	311
57	0	0	63 1987 APR [15] PEDIATRIC RESEARCH 21(4):A313-A313 KOHN DB; FEARON ER; WINKLESTEIN JA; VOGELSTEIN B; BLAESE RM WISKOTT-ALDRICH SYNDROME (WAS) CARRIER DETECTION BY X-CHROMOSOME INACTIVATION ANALYSIS	0	8
58	0	0	60 1987 MAY [15] JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 46(3):373-373 BIGNER SH; BURGER PC; WONG AJ; KINZLER KK; HAMILTON SR; et al. MORPHOLOGICAL-CHARACTERISTICS OF MALIGNANT HUMAN GLIOMAS (MHG) WITH GENE AMPLIFICATION	0	0
59	2	30	61 1987 MAY 28 NATURE 327(6120):293-297 BOS JL; FEARON ER; HAMILTON SR; VERLAANDEVRIES M; VANBOOM JH; et al. PREVALENCE OF RAS GENE-MUTATIONS IN HUMAN COLORECTAL CANCERS	20	1254
60	0	0	57 1987 [JUN 30] CYTOGENETICS AND CELL GENETICS 46(1-4):639-639 KINZLER KW; BIGNER SH; BIGNER DD; TRENT JM; LAW ML; et al. IDENTIFICATION OF AN AMPLIFIED, HIGHLY EXPRESSED GENE IN A HUMAN GLIOMA	0	2
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61	0	0	68 1987 [JUN 30] SEMINARS IN SURGICAL ONCOLOGY 3(3):149-151 FEINBERG AP; VOGELSTEIN B ALTERATIONS IN DNA METHYLATION IN HUMAN-COLON NEOPLASIA	0	10
62	5	26	52 1987 AUG [15] BLOOD 70(2):412-417 BAYLIN SB; FEARON ER; VOGELSTEIN B; DEBUSTROS A; SHARKIS SJ; et al. HYPERMETHYLATION OF THE 5' REGION OF THE CALCITONIN GENE IS A PROPERTY OF HUMAN LYMPHOID AND ACUTE MYELOID MALIGNANCIES	0	83
63	0	0	53 1987 SEP [15] CANCER GENETICS AND CYTOGENETICS 28(1):32-32 BIGNER SH; WONG AJ; MARK J; KINZLER KW; VOGELSTEIN B; et al. CHROMOSOMES AND GENE AMPLIFICATION IN MALIGNANT HUMAN GLIOMAS (MHG)	0	1
64	0	1	54 1987 SEP [15] CANCER GENETICS AND CYTOGENETICS 28(1):32-32 MELTZER P; COCCIA M; KINZLER K; VOGELSTEIN B; TRENT J RENATURATION GEL ANALYSIS OF AMPLIFIED DNA-SEQUENCES	0	0
65	9	54	56 1987 SEP 15 CANCER RESEARCH 47(18):4806-4813 VOGELSTEIN B; FEARON ER; HAMILTON SR; PREISINGER AC; WILLARD HF; et al. CLONAL ANALYSIS USING RECOMBINANT-DNA PROBES FROM THE X-CHROMOSOME	14	416
66	6	65	67 1987 OCT 9 SCIENCE 238(4824):193-197 FEARON ER; HAMILTON SR; VOGELSTEIN B CLONAL ANALYSIS OF HUMAN COLORECTAL TUMORS	11	476
67	4	39	65 1987 OCT [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 84(19):6899-6903 WONG AJ; BIGNER SH; BIGNER DD; KINZLER KW; HAMILTON SR; et al. INCREASED EXPRESSION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR GENE IN MALIGNANT GLIOMAS IS INVARIABLY ASSOCIATED WITH GENE AMPLIFICATION	12	462
68	3	20	55 1987 NOV [15] CANCER GENETICS AND CYTOGENETICS 29(1):165-170 BIGNER SH; WONG AJ; MARK J; MUHLBAIER LH; KINZLER KW; et al. RELATIONSHIP BETWEEN GENE AMPLIFICATION AND CHROMOSOMAL DEVIATIONS IN MALIGNANT HUMAN GLIOMAS	3	88
69	0	0	75 1988 JAN [15] LABORATORY INVESTIGATION 58(1):A47-A47 KERN S; BOS JL; FEARON ER; VOGELSTEIN B; HAMILTON SR THE RELATIONSHIP BETWEEN RAS GENE-MUTATIONS AND THE ADENOMA-CARCINOMA SEQUENCE IN THE COLORECTUM	0	0
70	0	0	76 1988 JAN [15] MODERN PATHOLOGY 1(1):A47-A47 KERN S; BOS JL; FEARON ER; VOGELSTEIN B; HAMILTON SR THE RELATIONSHIP BETWEEN RAS GENE-MUTATIONS AND THE ADENOMA-CARCINOMA SEQUENCE IN THE COLORECTUM	0	0
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71	6	40	77 1988 FEB [15] MOLECULAR AND CELLULAR BIOLOGY 8(2):522-530 ZEHNBAUER BA; SMALL D; BRODEUR GM; SEEGER R; VOGELSTEIN B CHARACTERIZATION OF N-MYC AMPLIFICATION UNITS IN HUMAN NEURO-BLASTOMA CELLS	1	46
72	2	7	74 1988 MAR [15] JOURNAL OF PATHOLOGY 154(3):205-206 HAMILTON SR; VOGELSTEIN B POINT MUTATIONS IN HUMAN NEOPLASIA	0	8
73	0	0	81 1988 MAR [15] PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 29:78-78 HUMPHREY PA; WONG AJ; VOGELSTEIN B; FRIEDMAN HS; BIGNER DD; et al. LOSS OF EPIDERMAL GROWTH-FACTOR RECEPTOR GENE AMPLIFICATION AS MALIGNANT HUMAN GLIOMAS ESTABLISH IN CULTURE	1	4
74	0	0	82 1988 MAR [15] PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH 29:393-393 SCHACKERT H; ITAYA T; HUNT B; FEARON E; VOGELSTEIN B; et al. SYSTEMIC IMMUNOPROTECTION AFFORDED BY TUMOR-CELLS TRANSFECTED WITH A FOREIGN (VIRAL) GENE	0	0
75	3	29	79 1988 MAR 24 NATURE 332(6162):371-374 KINZLER KW; RUPPERT JM; BIGNER SH; VOGELSTEIN B THE GLI GENE IS A MEMBER OF THE KRUPPEL FAMILY OF ZINC FINGER PROTEINS	9	236
76	3	35	70 1988 APR 15 CANCER RESEARCH 48(8):2231-2238 HUMPHREY PA; WONG AJ; VOGELSTEIN B; FRIEDMAN HS; WERNER MH; et al. AMPLIFICATION AND EXPRESSION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR GENE IN HUMAN GLIOMA XENOGRAFTS	6	143
77	4	21	73 1988 MAY [15] JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 47(3):191-205 BIGNER SH; BURGER PC; WONG AJ; WERNER MH; HAMILTON SR; et al. GENE AMPLIFICATION IN MALIGNANT HUMAN GLIOMAS - CLINICAL AND HISTOPATHOLOGIC ASPECTS	0	168
78	2	31	71 1988 JUN 1 CANCER RESEARCH 48(11):2975-2980 FEARON ER; ITAYA T; HUNT B; VOGELSTEIN B; FROST P INDUCTION IN A MURINE TUMOR OF IMMUNOGENIC TUMOR VARIANTS BY TRANSFECTION WITH A FOREIGN GENE	2	101
79	7	35	72 1988 [JUN 30] ISI ATLAS OF SCIENCE-BIOCHEMISTRY 1(4):333-336 BIGNER SH; VOGELSTEIN B; BIGNER DD CHROMOSOMAL-ABNORMALITIES AND GENE AMPLIFICATION IN MALIGNANT GLIOMAS	0	10
80	5	64	78 1988 AUG [15] MOLECULAR AND CELLULAR BIOLOGY 8(8):3104-3113 RUPPERT JM; KINZLER KW; WONG AJ; BIGNER SH; KAO FT; et al. THE GLI-KRUPPEL FAMILY OF HUMAN GENES	5	200
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81	7	55	80 1988 SEP 1 NEW ENGLAND JOURNAL OF MEDICINE 319(9):525-532 VOGELSTEIN B; FEARON ER; HAMILTON SR; KERN SE; PREISINGER AC; et al. GENETIC ALTERATIONS DURING COLORECTAL-TUMOR DEVELOPMENT	49	3189
82	3	28	69 1988 NOV [15] BLOOD 72(5):1735-1739 FEARON ER; KOHN DB; WINKELSTEIN JA; VOGELSTEIN B; BLAESE RM CARRIER DETECTION IN THE WISKOTT ALDRICH SYNDROME	0	82
83	7	89	91 1989 APR 14 SCIENCE 244(4901):207-211 VOGELSTEIN B; FEARON ER; KERN SE; HAMILTON SR; PREISINGER AC; et al. ALLELOTYPE OF COLORECTAL CARCINOMAS	26	1097
84	7	69	92 1989 APR 14 SCIENCE 244(4901):217-221 BAKER SJ; FEARON ER; NIGRO JM; HAMILTON SR; PREISINGER AC; et al. CHROMOSOME-17 DELETIONS AND P53 GENE-MUTATIONS IN COLORECTAL CARCINOMAS	38	1472
85	2	21	85 1989 APR [15] HUMAN GENETICS 82(1):1-2 ARHEDEN K; RONNE M; MANDAHL N; HEIM S; KINZLER KW; et al. INSITU HYBRIDIZATION LOCALIZES THE HUMAN PUTATIVE ONCOGENE GLI TO CHROMOSOME SUBBANDS 12Q13.3-14.1	5	35
86	1	19	86 1989 MAY 15 INTERNATIONAL JOURNAL OF CANCER 43(5):823-827 SCHACKERT HK; ITAYA T; SCHACKERT G; FEARON E; VOGELSTEIN B; et al. SYSTEMIC IMMUNITY AGAINST A MURINE COLON-TUMOR (CT-26) PRODUCED BY IMMUNIZATION WITH SYNGENEIC CELLS EXPRESSING A TRANSFECTED VIRAL GENE-PRODUCT	0	15
87	1	17	90 1989 MAY 25 NUCLEIC ACIDS RESEARCH 17(10):3645-3653 KINZLER KW; VOGELSTEIN B WHOLE GENOME PCR - APPLICATION TO THE IDENTIFICATION OF SEQUENCES BOUND BY GENE REGULATORY PROTEINS	12	152
88	4	40	87 1989 JUN 2 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 261(21):3099-3103 KERN SE; FEARON ER; TERSMETTE KWF; ENTERLINE JP; LEPPERT M; et al. ALLELIC LOSS IN COLORECTAL-CARCINOMA	7	322
89	0	0	83 1989 AUG [15] CANCER AND METASTASIS REVIEWS 8(2):166-166 VOGELSTEIN B GENETIC ALTERATIONS UNDERLYING COLORECTAL TUMOR-DEVELOPMENT	0	0
90	0	0	84 1989 SEP [15] CANCER GENETICS AND CYTOGENETICS 41(2):226-226 BIGNER SH; VOGELSTEIN B; MARK J; BIGNER DD CYTOGENETICS AND GENE AMPLIFICATION IN MALIGNANT HUMAN-BRAIN TUMORS	0	3
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91	0	0	88 1989 SEP 15 MUNCHENER MEDIZINISCHE WOCHENSCHRIFT 131(37):38-& VOGELSTEIN B MECHANISMS OF METASTASIS	0	0
92	2	28	89 1989 DEC 7 NATURE 342(6250):705-708 NIGRO JM; BAKER SJ; PREISINGER AC; JESSUP JM; HOSTETTER R; et al. MUTATIONS IN THE P53 GENE OCCUR IN DIVERSE HUMAN-TUMOR TYPES	36	2358
93	6	82	110 1990 JAN 5 SCIENCE 247(4938):49-56 FEARON ER; CHO KR; NIGRO JM; KERN SE; SIMONS JW; et al. IDENTIFICATION OF A CHROMOSOME-18Q GENE THAT IS ALTERED IN COLORECTAL CANCERS	27	1419
94	0	44	98 1990 FEB 9 CELL 60(3):397-403 FEARON ER; PARDOLL DM; ITAYA T; GOLUMBEK P; LEVITSKY HI; et al. INTERLEUKIN-2 PRODUCTION BY TUMOR-CELLS BYPASSES T-HELPER FUNCTION IN THE GENERATION OF AN ANTITUMOR RESPONSE	1	937
95	7	30	103 1990 FEB [15] MOLECULAR AND CELLULAR BIOLOGY 10(2):634-642 KINZLER KW; VOGELSTEIN B THE GLI GENE ENCODES A NUCLEAR-PROTEIN WHICH BINDS SPECIFIC SEQUENCES IN THE HUMAN GENOME	4	178
96	7	28	94 1990 APR 15 CANCER RESEARCH 50(8):2347-2350 BIGNER SH; FRIEDMAN HS; VOGELSTEIN B; OAKES WJ; BIGNER DD AMPLIFICATION OF THE C-MYC GENE IN HUMAN MEDULLOBLASTOMA CELL-LINES AND XENOGRAFTS	1	113
97	2	2	107 1990 MAY 11 NUCLEIC ACIDS RESEARCH 18(9):2834-2834 KINZLER KW; VOGELSTEIN B ECORI POLYMORPHISM WITHIN THE GLI GENE (CHROMOSOME 12Q13.3-14.1)	0	6
98	0	0	102 1990 MAY [15] JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 49(3):320-320 FULLER GN; BURGER PC; SCHOLD SC; PREISINGER A; WONG AJ; et al. GENE AMPLIFICATION IN HUMAN GLIOMAS	0	7
99	9	77	99 1990 JUN 1 CELL 61(5):759-767 FEARON ER; VOGELSTEIN B A GENETIC MODEL FOR COLORECTAL TUMORIGENESIS	34	4851
100	2	28	108 1990 JUN [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(11):4207-4211 HUMPHREY PA; WONG AJ; VOGELSTEIN B; ZALUTSKY MR; FULLER GN; et al. ANTISYNTHETIC PEPTIDE ANTIBODY REACTING AT THE FUSION JUNCTION OF DELETION MUTANT EPIDERMAL GROWTH-FACTOR RECEPTORS IN HUMAN GLIOBLASTOMA	1	164
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101	2	19	101 1990 JUL [15] GENES CHROMOSOMES & CANCER 2(2):159-162 VOGELSTEIN B; CIVIN CI; PREISINGER AC; KRISCHER JP; STEUBER P; et al. RAS GENE-MUTATIONS IN CHILDHOOD ACUTE MYELOID-LEUKEMIA - A PEDIATRIC ONCOLOGY GROUP-STUDY	0	22
102	5	43	111 1990 AUG 24 SCIENCE 249(4971):912-915 BAKER SJ; MARKOWITZ S; FEARON ER; WILLSON JKV; VOGELSTEIN B SUPPRESSION OF HUMAN COLORECTAL-CARCINOMA CELL-GROWTH BY WILD-TYPE-P53	30	1527
103	0	0	93 1990 SEP [15] BRITISH JOURNAL OF CANCER 62(3):475-475 VOGELSTEIN B GENETIC ALTERATIONS UNDERLYING COLORECTAL TUMORIGENESIS	0	0
104	6	52	104 1990 OCT [15] MOLECULAR AND CELLULAR BIOLOGY 10(10):5408-5415 RUPPERT JM; VOGELSTEIN B; ARHEDEN K; KINZLER KW GL13 ENCODES A 190-KILODALTON PROTEIN WITH MULTIPLE REGIONS OF GLI SIMILARITY	1	122
105	3	60	105 1990 NOV [15] MOLECULAR AND CELLULAR BIOLOGY 10(11):5772-5781 DILLER L; KASSEL J; NELSON CE; GRYKA MA; LITWAK G; et al. P53 FUNCTIONS AS A CELL-CYCLE CONTROL PROTEIN IN OSTEOSARCOMAS	11	757
106	8	62	95 1990 DEC 1 CANCER RESEARCH 50(23):7717-7722 BAKER SJ; PREISINGER AC; JESSUP JM; PARASKEVA C; MARKOWITZ S; et al. P53 GENE-MUTATIONS OCCUR IN COMBINATION WITH 17P ALLELIC DELETIONS AS LATE EVENTS IN COLORECTAL TUMORIGENESIS	29	889
107	4	43	96 1990 DEC 15 CANCER RESEARCH 50(24):7902-7907 PAULIEN S; TURCCAREL C; DALCIN P; JANISAIT S; SREEKANTAIAH C; et al. MYXOID LIPOSARCOMA WITH T(12-16) (Q13-P11) CONTAINS SITE-SPECIFIC DIFFERENCES IN METHYLATION PATTERNS SURROUNDING A ZINC-FINGER GENE MAPPED TO THE BREAKPOINT REGION ON CHROMOSOME-12	0	24
108	3	29	97 1990 DEC 15 CANCER RESEARCH 50(24):8017-8022 BIGNER SH; HUMPHREY PA; WONG AJ; VOGELSTEIN B; MARK J; et al. CHARACTERIZATION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR IN HUMAN GLIOMA CELL-LINES AND XENOGRAFTS	0	137
109	4	59	100 1990 DEC [15] CELL GROWTH & DIFFERENTIATION 1(12):571-580 HINDS PW; FINLAY CA; QUARTIN RS; BAKER SJ; FEARON ER; et al. MUTANT P53 DNA CLONES FROM HUMAN COLON CARCINOMAS COOPERATE WITH RAS IN TRANSFORMING PRIMARY RAT-CELLS - A COMPARISON OF THE HOT-SPOT MUTANT PHENOTYPES	4	421
110	3	48	109 1990 DEC [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(23):9275-9279 FRIEDMAN PN; KERN SE; VOGELSTEIN B; PRIVES C WILD-TYPE, BUT NOT MUTANT, HUMAN P53 PROTEINS INHIBIT THE REPLICATION ACTIVITIES OF SIMIAN VIRUS-40 LARGE TUMOR-ANTIGEN	5	111
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111	0	11	106 1990 DEC 20 NATURE 348(6303):681-682 VOGELSTEIN B CANCER - A DEADLY INHERITANCE	9	282
112	0	0	124 1991 JAN [15] LABORATORY INVESTIGATION 64(1):A39-A39 OFFERHAUS GJA; CORNELISSE CJ; TERSMETTE KWF; FLOYD J; KERN SE; et al. THE RELATIONSHIP OF MOLECULAR GENETIC ALTERATIONS AND ABNORMAL TOTAL DNA CONTENT IN COLORECTAL-CARCINOMA	0	2
113	3	51	128 1991 JAN [15] ONCOGENE 6(1):131-136 KERN SE; KINZLER KW; BAKER SJ; NIGRO JM; ROTTER V; et al. MUTANT P53 PROTEINS BIND DNA ABNORMALLY INVITRO	6	159
114	3	41	121 1991 FEB 8 CELL 64(3):607-613 NIGRO JM; CHO KR; FEARON ER; KERN SE; RUPPERT JM; et al. SCRAMBLED EXONS	2	74
115	7	37	125 1991 MAR [15] MOLECULAR AND CELLULAR BIOLOGY 11(3):1724-1728 RUPPERT JM; VOGELSTEIN B; KINZLER KW THE ZINC FINGER PROTEIN GLI TRANSFORMS PRIMARY-CELLS IN COOPERATION WITH ADENOVIRUS E1A	0	75
116	8	43	131 1991 MAR 15 SCIENCE 251(4999):1366-1370 KINZLER KW; NILBERT MC; VOGELSTEIN B; BRYAN TM; LEVY DB; et al. IDENTIFICATION OF A GENE LOCATED AT CHROMOSOME-5Q21 THAT IS MUTATED IN COLORECTAL CANCERS	25	495
117	7	54	132 1991 MAY 3 SCIENCE 252(5006):706-709 SIDRANSKY D; VONESCHENBACH A; TSAI YC; JONES P; SUMMERHAYES I; et al. IDENTIFICATION OF P53 GENE-MUTATIONS IN BLADDER CANCERS AND URINE SAMPLES	16	674
118	5	65	122 1991 JUN 14 CELL 65(6):1083-1091 BARGONETTI J; FRIEDMAN PN; KERN SE; VOGELSTEIN B; PRIVES C WILD-TYPE BUT NOT MUTANT P53 IMMUNOPURIFIED PROTEINS BIND TO SEQUENCES ADJACENT TO THE SV40 ORIGIN OF REPLICATION	5	339
119	1	21	116 1991 JUN [15] CANCER IMMUNOLOGY IMMUNOTHERAPY 33(4):267-273 ITAYA T; FEARON E; FIESINGER T; HUNT B; VOGELSTEIN B; et al. IMMUNOGENICITY OF A NON-CLASS-I MHC EXPRESSING MURINE TUMOR TRANSFECTED WITH THE INFLUENZA-VIRUS HEMAGGLUTININ OR MURINE INTERLEUKIN-2 GENES	0	6
120	8	51	130 1991 JUN [15] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(11):4976-4980 MELTZER SJ; YIN J; HUANG Y; MCDANIEL TK; NEWKIRK C; et al. REDUCTION TO HOMOZYGOSITY INVOLVING P53 IN ESOPHAGEAL CANCERS DEMONSTRATED BY THE POLYMERASE CHAIN-REACTION	1	180
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121	8	35	133 1991 JUN 21 SCIENCE 252(5013):1708-1711 KERN SE; KINZLER KW; BRUSKIN A; JAROSZ D; FRIEDMAN P; et al. IDENTIFICATION OF P53 AS A SEQUENCE-SPECIFIC DNA-BINDING PROTEIN	11	800
122	7	95	134 1991 JUL 5 SCIENCE 253(5015):49-53 HOLLSTEIN M; SIDRANSKY D; VOGELSTEIN B; HARRIS CC P53 MUTATIONS IN HUMAN CANCERS	31	5145
123	5	36	123 1991 JUL 17 JOURNAL OF THE NATIONAL CANCER INSTITUTE 83(14):1004-1009 KOVACH JS; MCGOVERN RM; CASSADY JD; SWANSON SK; WOLD LE; et al. DIRECT SEQUENCING FROM TOUCH PREPARATIONS OF HUMAN CARCINOMAS - ANALYSIS OF P53 MUTATIONS IN BREAST CARCINOMAS	0	96
124	8	59	135 1991 AUG 9 SCIENCE 253(5020):661-665 KINZLER KW; NILBERT MC; SU LK; VOGELSTEIN B; BRYAN TM; et al. IDENTIFICATION OF FAP LOCUS GENES FROM CHROMOSOME-5Q21	33	1235
125	10	50	136 1991 AUG 9 SCIENCE 253(5020):665-669 NISHISHO I; NAKAMURA Y; MIYOSHI Y; MIKI Y; ANDO H; et al. MUTATIONS OF CHROMOSOME-5Q21 GENES IN FAP AND COLORECTAL-CANCER PATIENTS	38	1000
126	2	43	117 1991 AUG 15 CANCER RESEARCH 51(16):4135-4140 PELTOMAKI P; SISTONEN P; MECKLIN JP; PYLKKANEN L; JARVINEN H; et al. EVIDENCE SUPPORTING EXCLUSION OF THE DCC GENE AND A PORTION OF CHROMOSOME-18Q AS THE LOCUS FOR SUSCEPTIBILITY TO HEREDITARY NONPOLYPOSIS COLORECTAL-CARCINOMA IN 5 KINDREDS	3	42
127	5	20	118 1991 SEP 1 CANCER RESEARCH 51(17):4721-4723 SAYLORS RL; SIDRANSKY D; FRIEDMAN HS; BIGNER SH; BIGNER DD; et al. INFREQUENT P53 GENE-MUTATIONS IN MEDULLOBLASTOMAS	0	130
128	0	0	112 1991 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 49(4):21-21 HEDGE PJ; MCKECHNIE D; GAMMACK A; FINNIEAR R; ELLSTON J; et al. A 1.6MB YAC CONTIG AT THE FAP LOCUS (5Q21-Q22) CONTAINS THE GENE FOR MCC AND OTHER CANDIDATE GENES	0	0
129	0	0	113 1991 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 49(4):24-24 VOGELSTEIN B GENETIC ALTERATIONS UNDERLYING COLORECTAL TUMORIGENESIS	0	0
130	0	0	114 1991 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 49(4):354-354 PELTOMAKI P; SISTONEN P; MECKLIN JP; PYLKKANEN L; JARVINEN H; et al. EXCLUSION OF THE DCC GENE AND PART OF 18Q AS THE LOCUS FOR SUSCEPTIBILITY TO HEREDITARY NONPOLYPOSIS COLORECTAL-CARCINOMA IN 5 KINDREDS	0	0
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131	0	0	115 1991 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 49(4):388-388 SCHNEIDER S; ZEHNBAUER B; VOGELSTEIN B; BRODEUR G STRUCTURAL-ANALYSIS OF THE MYCN AMPLIFIED DOMAIN IN NEUROBLASTOMAS USING YEAST ARTIFICIAL-CHROMOSOME (YAC) CLONING	0	0
132	4	36	119 1991 OCT 15 CANCER RESEARCH 51(20):5449-5453 MILLIKIN D; MEESE E; VOGELSTEIN B; WITKOWSKI C; TRENT J LOSS OF HETEROZYGOSITY FOR LOCI ON THE LONG ARM OF CHROMOSOME-6 IN HUMAN-MALIGNANT MELANOMA	0	180
133	5	47	129 1991 OCT [15] ONCOGENE 6(10):1791-1797 CASEY G; LOHSUEH M; LOPEZ ME; VOGELSTEIN B; STANBRIDGE EJ GROWTH SUPPRESSION OF HUMAN BREAST-CANCER CELLS BY THE INTRODUCTION OF A WILD-TYPE P53 GENE	1	228
134	7	53	120 1991 DEC 1 CANCER RESEARCH 51(23):6304-6311 KASTAN MB; ONYEKWERE O; SIDRANSKY D; VOGELSTEIN B; CRAIG RW PARTICIPATION OF P53 PROTEIN IN THE CELLULAR-RESPONSE TO DNA DAMAGE	12	3035
135	1	2	126 1991 DEC 25 NUCLEIC ACIDS RESEARCH 19(24):6965-6965 DEVILEE P; VANVLIET M; CHO KR; VOGELSTEIN B HINDIII POLYMORPHISM IN THE DCC GENE	0	5
136	1	2	127 1991 DEC 25 NUCLEIC ACIDS RESEARCH 19(24):6983-6983 PARRY PJ; MARKIE D; FEARON ER; NIGRO JM; VOGELSTEIN B; et al. PCR-BASED DETECTION OF 2 MSPI POLYMORPHIC SITES AT D18S8	0	14
137	6	19	153 1992 JAN [15] JAPANESE JOURNAL OF CANCER RESEARCH 83(1):10-14 MIYOSHI Y; NISHISHO I; MIKI Y; MORI T; KINZLER KW; et al. INSERTION DELETION POLYMORPHISM AND OTHER RESTRICTION-FRAGMENT-LENGTH-POLYMORPHISMS IN THE MCC GENE	1	4
138	0	0	156 1992 JAN [15] LABORATORY INVESTIGATION 66(1):A46-A46 MULDER JWR; OFFERHAUS GJA; DEFEYTER EP; FLOYD JF; KERN SE; et al. THE RELATIONSHIP OF QUANTITATIVE NUCLEAR MORPHOLOGY TO MOLECULAR GENETIC ALTERATIONS IN THE ADENOMA-CARCINOMA SEQUENCE OF THE LARGE-BOWEL	0	0
139	0	0	157 1992 JAN [15] LABORATORY INVESTIGATION 66(1):A47-A47 REDSTON MS; KERN SE; VOGELSTEIN B; HAMILTON SR EXPRESSION OF OA519 (HAPTOGLOBIN-RELATED PROTEIN EPITOPES) IN COLORECTAL CARCINOMAS - COMPARISON WITH MOLECULAR GENETIC ALTERATIONS AND METASTASIS	0	3
140	2	10	161 1992 JAN 16 NATURE 355(6357):209-210 VOGELSTEIN B; KINZLER KW CANCER - CARCINOGENS LEAVE FINGERPRINTS	0	126
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141	6	25	141 1992 FEB 1 CANCER RESEARCH 52(3):643-645 MIKI Y; NISHISHO I; HORII A; MIYOSHI Y; UTSUNOMIYA J; et al. DISRUPTION OF THE APC GENE BY A RETROTRANSPOSAL INSERTION OF L1 SEQUENCE IN A COLON CANCER	0	155
142	5	15	162 1992 FEB 27 NATURE 355(6363):846-848 SIDRANSKY D; MIKKELSEN T; SCHWECHHEIMER K; ROSENBLUM ML; CAVANEE W; et al. CLONAL EXPANSION OF P53 MUTANT-CELLS IS ASSOCIATED WITH BRAIN-TUMOR PROGRESSION	3	561
143	9	34	166 1992 MAR 12 NEW ENGLAND JOURNAL OF MEDICINE 326(11):737-740 SIDRANSKY D; FROST P; VONESCHENBACH A; OYASU R; PREISINGER AC; et al. CLONAL ORIGIN OF BLADDER-CANCER	2	312
144	6	26	147 1992 MAR [15] CHEST 101(3):S19-S20 BENNETT WP; HOLLSTEIN MC; HSU IC; SIDRANSKY D; LANE DP; et al. MUTATIONAL SPECTRA AND IMMUNOHISTOCHEMICAL ANALYSES OF P53 IN HUMAN CANCERS	0	7
145	7	41	158 1992 MAR [15] MOLECULAR AND CELLULAR BIOLOGY 12(3):1357-1365 NIGRO JM; SIKORSKI R; REED SI; VOGELSTEIN B HUMAN P53 AND CDC2HS GENES COMBINE TO INHIBIT THE PROLIFERATION OF SACCHAROMYCES-CEREVISIAE	5	85
146	11	55	159 1992 MAR [15] MOLECULAR AND CELLULAR BIOLOGY 12(3):1387-1395 GOYETTE MC; CHO K; FASCHING CL; LEVY DB; KINZLER KW; et al. PROGRESSION OF COLORECTAL-CANCER IS ASSOCIATED WITH MULTIPLE TUMOR SUPPRESSOR GENE DEFECTS BUT INHIBITION OF TUMORIGENICITY IS ACCOMPLISHED BY CORRECTION OF ANY SINGLE DEFECT VIA CHROMOSOME TRANSFER	6	212
147	4	54	168 1992 MAR [15] ONCOGENE 7(3):553-561 NARAYANAN R; LAWLOR KG; SCHAAPVELD RQJ; CHO KR; VOGELSTEIN B; et al. ANTISENSE RNA TO THE PUTATIVE TUMOR-SUPPRESSOR GENE DCC TRANSFORMS RAT-1 FIBROBLASTS	2	83
148	2	32	142 1992 APR 1 CANCER RESEARCH 52(7):1780-1785 FONG CT; WHITE PS; PETERSON K; SAPIENZA C; CAVENEE WK; et al. LOSS OF HETEROZYGOSITY FOR CHROMOSOME-1 OR CHROMOSOME-14 DEFINES SUBSETS OF ADVANCED NEUROBLASTOMAS	0	164
149	7	56	169 1992 APR 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(7):2759-2763 GERWIN BI; SPILLARE E; FORRESTER K; LEHMAN TA; KISPERT J; et al. MUTANT-P53 CAN INDUCE TUMORIGENIC CONVERSION OF HUMAN BRONCHIAL EPITHELIAL-CELLS AND REDUCE THEIR RESPONSIVENESS TO A NEGATIVE GROWTH-FACTOR, TRANSFORMING GROWTH FACTOR-BETA(1)	0	116
150	4	29	170 1992 APR 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(7):2965-2969 WONG AJ; RUPPERT JM; BIGNER SH; GRZESCHIK CH; HUMPHREY PA; et al. STRUCTURAL ALTERATIONS OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR GENE IN HUMAN GLIOMAS	0	269
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151	8	46	172 1992 APR 3 SCIENCE 256(5053):102-105 SIDRANSKY D; TOKINO T; HAMILTON SR; KINZLER KW; LEVIN B; et al. IDENTIFICATION OF RAS ONCOGENE MUTATIONS IN THE STOOL OF PATIENTS WITH CURABLE COLORECTAL TUMORS	8	468
152	10	20	165 1992 APR [15] NATURE GENETICS 1(1):45-49 ELDEIRY WS; KERN SE; PIETENPOL JA; KINZLER KW; VOGELSTEIN B DEFINITION OF A CONSENSUS BINDING-SITE FOR P53	15	990
153	6	26	173 1992 MAY 1 SCIENCE 256(5057):668-670 SU LK; KINZLER KW; VOGELSTEIN B; PREISINGER AC; MOSER AR; et al. MULTIPLE INTESTINAL NEOPLASIA CAUSED BY A MUTATION IN THE MURINE HOMOLOG OF THE APC GENE	14	528
154	12	49	174 1992 MAY 8 SCIENCE 256(5058):827-830 KERN SE; PIETENPOL JA; THIAGALINGAM S; SEYMOUR A; KINZLER KW; et al. ONCOGENIC FORMS OF P53 INHIBIT P53-REGULATED GENE-EXPRESSION	11	850
155	7	21	143 1992 MAY 15 CANCER RESEARCH 52(10):2984-2986 SIDRANSKY D; TOKINO T; HELZLSOUER K; ZEHNBAUER B; RAUSCH G; et al. INHERITED P53 GENE-MUTATIONS IN BREAST-CANCER	1	147
156	8	41	150 1992 MAY [15] GASTROENTEROLOGY 102(5):1612-1619 OFFERHAUS GJA; DEFEYTER EP; CORNELISSE CJ; TERSMETTE KWF; FLOYD J; et al. THE RELATIONSHIP OF DNA ANEUPLOIDY TO MOLECULAR GENETIC ALTERATIONS IN COLORECTAL-CARCINOMA	2	105
157	6	26	171 1992 MAY 15 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(10):4452-4456 MIYOSHI Y; ANDO H; NAGASE H; NISHISHO I; HORII A; et al. GERM-LINE MUTATIONS OF THE APC GENE IN 53 FAMILIAL ADENOMATOUS POLYPOSIS PATIENTS	9	358
158	5	22	148 1992 [JUN 30] COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 57:345-351 HEDRICK L; CHO KR; BOYD J; RISINGER J; VOGELSTEIN B DCC - A TUMOR-SUPPRESSOR GENE EXPRESSED ON THE CELL-SURFACE	3	25
159	1	11	149 1992 [JUN 30] CYTOGENETICS AND CELL GENETICS 61(4):237-242 PLAETKE R; WEBER J; WOOD S; DEAN M; JEFFREYS AJ; et al. REPORT OF THE 2ND INTERNATIONAL WORKSHOP ON HUMAN CHROMOSOME-5 MAPPING - CONSENSUS GENETIC-MAP	0	2
160	10	25	154 1992 [JUN 30] JOURNAL OF CELLULAR BIOCHEMISTRY :137-141 CHO KR; VOGELSTEIN B SUPPRESSOR GENE ALTERATIONS IN THE COLORECTAL ADENOMA-CARCINOMA SEQUENCE	0	0
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161	11	31	163 1992 JUL 2 NATURE 358(6381):80-83 OLINER JD; KINZLER KW; MELTZER PS; GEORGE DL; VOGELSTEIN B AMPLIFICATION OF A GENE ENCODING A P53-ASSOCIATED PROTEIN IN HUMAN SARCOMAS	12	1226
162	0	0	167 1992 AUG 6 NEW ENGLAND JOURNAL OF MEDICINE 327(6):434-434 SIDRANSKY D; VOGELSTEIN B; FROST P; VONESCHENBACH AC MONOCLONALITY OF MULTIPLE BLADDER CANCERS - REPLY	0	0
163	6	23	144 1992 AUG 15 CANCER RESEARCH 52(16):4530-4533 PELTOMAKI P; SISTONEN P; MECKLIN JP; PYLKKANEN L; AALTONEN L; et al. EVIDENCE THAT THE MCC-APC GENE REGION IN 5Q21 IS NOT THE SITE FOR SUSCEPTIBILITY TO HEREDITARY NONPOLYPOSIS COLORECTAL-CARCINOMA	1	27
164	5	66	151 1992 AUG [15] GENOMICS 13(4):1281-1288 JUSTICE MJ; GILBERT DJ; KINZLER KW; VOGELSTEIN B; BUCHBERG AM; et al. A MOLECULAR GENETIC-LINKAGE MAP OF MOUSE CHROMOSOME-18 REVEALS EXTENSIVE LINKAGE CONSERVATION WITH HUMAN CHROMOSOME-5 AND CHROMOSOME-18	1	53
165	8	31	145 1992 AUG 21 CELL 70(4):523-526 VOGELSTEIN B; KINZLER KW P53 FUNCTION AND DYSFUNCTION	13	1626
166	7	92	139 1992 SEP 1 CANCER 70(5):1300-1312 LYNCH HT; WATSON P; SMYRK TC; LANSPA SJ; BOMAN BM; et al. COLON CANCER GENETICS	0	26
167	13	38	140 1992 SEP 15 CANCER 70(6):1727-1731 CHO KR; VOGELSTEIN B GENETIC ALTERATIONS IN THE ADENOMA CARCINOMA SEQUENCE	0	144
168	1	7	155 1992 SEP [15] JOURNAL OF SURGICAL ONCOLOGY 51(1):5-7 SHAH KV; DANIEL RW; SIMONS JW; VOGELSTEIN B INVESTIGATION OF COLON CANCERS FOR HUMAN PAPILLOMAVIRUS GENOMIC SEQUENCES BY POLYMERASE CHAIN-REACTION	0	6
169	11	22	164 1992 SEP 17 NATURE 359(6392):235-237 POWELL SM; ZILZ N; BEAZERBARCLAY Y; BRYAN TM; HAMILTON SR; et al. APC MUTATIONS OCCUR EARLY DURING COLORECTAL TUMORIGENESIS	27	793
170	10	44	137 1992 OCT [15] AMERICAN JOURNAL OF PATHOLOGY 141(4):797-804 MULDER JWR; OFFERHAUS GJA; DEFEYTER EP; FLOYD JJ; KERN SE; et al. THE RELATIONSHIP OF QUANTITATIVE NUCLEAR MORPHOLOGY TO MOLECULAR GENETIC ALTERATIONS IN THE ADENOMA-CARCINOMA SEQUENCE OF THE LARGE-BOWEL	0	40
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171	6	19	175 1992 OCT [15] TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 168(2):141-147 NAKAMURA Y; NISHISHO I; KINZLER KW; VOGELSTEIN B; MIYOSHI Y; et al. MUTATIONS OF THE APC (ADENOMATOUS-POLYPOSIS-COLI) GENE IN FAP (FAMILIAL-POLYPOSIS-COLI) PATIENTS AND IN SPORADIC COLORECTAL TUMORS	0	11
172	3	3	138 1992 OCT 28 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 660:283-285 LAWLOR KG; TELANG NT; OSBORNE MP; SCHAAPVELD RQ; CHO KR; et al. ANTISENSE RNA TO THE PUTATIVE TUMOR SUPPRESSOR GENE DELETED IN COLORECTAL-CANCER TRANSFORMS FIBROBLASTS	0	2
173	7	56	146 1992 NOV 13 CELL 71(4):587-597 KASTAN MB; ZHAN QM; ELDEIRY WS; CARRIER F; JACKS T; et al. A MAMMALIAN-CELL CYCLE CHECKPOINT PATHWAY UTILIZING P53 AND GADD45 IS DEFECTIVE IN ATAXIA-TELANGIECTASIA	12	2526
174	0	0	152 1992 NOV 15 HOSPITAL PRACTICE 27(11):51-58 KINZLER KW; VOGELSTEIN B THE COLORECTAL-CANCER GENE HUNT - CURRENT FINDINGS	1	9
175	4	63	160 1992 DEC [15] MOLECULAR AND CELLULAR BIOLOGY 12(12):5563-5570 SCHNEIDER SS; HIEMSTRA JL; ZEHNBAUER BA; TAILLONMILLER P; LEPASLIER DL; et al. ISOLATION AND STRUCTURAL-ANALYSIS OF A 1.2-MEGABASE N-MYC AMPLICON FROM A HUMAN NEUROBLASTOMA	0	38
176	8	29	182 1993 JAN [15] GENOMICS 15(1):3-8 LUONGO C; GOULD KA; SU LK; KINZLER KW; VOGELSTEIN B; et al. MAPPING OF MULTIPLE INTESTINAL NEOPLASIA (MIN) TO PROXIMAL CHROMOSOME-18 OF THE MOUSE	0	44
177	0	0	184 1993 JAN [15] LABORATORY INVESTIGATION 68(1):A43-A43 BAAS IO; MULDER JWR; OFFERHAUS GJA; VOGELSTEIN B; HAMILTON SR IMMUNOHISTOCHEMISTRY OF ALTERED-P53 SUPPRESSOR GENE-PRODUCT IN COLORECTAL NEOPLASMS	0	0
178	6	27	189 1993 APR 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(7):2846-2850 SMITH KJ; JOHNSON KA; BRYAN TM; HILL DE; MARKOWITZ S; et al. THE APC GENE-PRODUCT IN NORMAL AND TUMOR-CELLS	21	320
179	3	25	193 1993 APR [15] TRENDS IN GENETICS 9(4):138-141 VOGELSTEIN B; KINZLER KW THE MULTISTEP NATURE OF CANCER	2	758
180	6	27	185 1993 APR 29 NATURE 362(6423):857-860 OLINER JD; PIETENPOL JA; THIAGALINGAM S; GVURIS J; KINZLER KW; et al. ONCOPROTEIN MDM2 CONCEALS THE ACTIVATION DOMAIN OF TUMOR SUPPRESSOR-P53	6	755
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181	3	69	176 1993 MAY 1 CANCER RESEARCH 53(9):1986-1989 LEACH FS; ELLEDGE SJ; SHERR CJ; WILLSON JKV; MARKOWITZ S; et al. AMPLIFICATION OF CYCLIN GENES IN COLORECTAL CARCINOMAS	1	174
182	6	32	190 1993 MAY 7 SCIENCE 260(5109):810-812 PELTOMAKI P; AALTONEN LA; SISTONEN P; PYLKKANEN L; MECKLIN JP; et al. GENETIC-MAPPING OF A LOCUS PREDISPOSING TO HUMAN COLORECTAL-CANCER	15	626
183	9	38	191 1993 MAY 7 SCIENCE 260(5109):812-816 AALTONEN LA; PELTOMAKI P; LEACH FS; SISTONEN P; PYLKKANEN L; et al. CLUES TO THE PATHOGENESIS OF FAMILIAL COLORECTAL-CANCER	36	1811
184	8	25	177 1993 MAY 15 CANCER RESEARCH 53(10):2231-2234 LEACH FS; TOKINO T; MELTZER P; BURRELL M; OLINER JD; et al. P53 MUTATION AND MDM2 AMPLIFICATION IN HUMAN SOFT-TISSUE SARCOMAS	1	388
185	0	15	186 1993 JUN 10 NATURE 363(6429):495-496 KINZLER KW; VOGELSTEIN B CANCER - A GENE FOR NEUROFIBROMATOSIS-2	0	12
186	7	24	178 1993 JUN 15 CANCER RESEARCH 53(12):2728-2731 SU LK; JOHNSON KA; SMITH KJ; HILL DE; VOGELSTEIN B; et al. ASSOCIATION BETWEEN WILD-TYPE AND MUTANT APC GENE-PRODUCTS	6	148
187	6	22	183 1993 OCT [15] INTERNATIONAL JOURNAL OF ONCOLOGY 3(4):769-772 TOKINO T; DAVIDSON N; HELZLSOUER K; ZEHNBAUER B; NAKAMURA Y; et al. ABSENCE OF GERMLINE PROHIBITIN MUTATIONS IN EARLY-ONSET BREAST-CANCER	0	7
188	7	31	188 1993 NOV 11 NUCLEIC ACIDS RESEARCH 21(22):5192-5197 OLINER JD; KINZLER KW; VOGELSTEIN B IN-VIVO CLONING OF PCR PRODUCTS IN ESCHERICHIA-COLI	0	36
189	14	73	179 1993 NOV 19 CELL 75(4):817-825 ELDEIRY WS; TOKINO T; VELCULESCU VE; LEVY DB; PARSONS R; et al. WAF1, A POTENTIAL MEDIATOR OF P53 TUMOR SUPPRESSION	24	4823
190	7	42	192 1993 DEC 10 SCIENCE 262(5140):1734-1737 SU LK; VOGELSTEIN B; KINZLER KW ASSOCIATION OF THE APC TUMOR-SUPPRESSOR PROTEIN WITH CATENINS	17	832
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191	9	61	180 1993 DEC 17 CELL 75(6):1215-1225 LEACH FS; NICOLAIDES NC; PAPADOPOULOS N; LIU B; JEN J; et al. MUTATIONS OF A MUTS HOMOLOG IN HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER	32	1578
192	4	41	181 1993 DEC 17 CELL 75(6):1227-1236 PARSONS R; LI GM; LONGLEY MJ; FANG WH; PAPADOPOULOS N; et al. HYPERMUTABILITY AND MISMATCH REPAIR DEFICIENCY IN RER+ TUMOR-CELLS	24	732
193	6	38	187 1993 DEC 30 NEW ENGLAND JOURNAL OF MEDICINE 329(27):1982-1987 POWELL SM; PETERSEN GM; KRUSH AJ; BOOKER S; JEN J; et al. MOLECULAR DIAGNOSIS OF FAMILIAL ADENOMATOUS POLYPOSIS	25	451
194	6	37	217 1994 JAN [15] JOURNAL OF PATHOLOGY 172(1):5-12 BAAS IO; MULDER JWR; OFFERHAUS GJA; VOGELSTEIN B; HAMILTON SR EVALUATION OF 6 ANTIBODIES FOR IMMUNOHISTOCHEMISTRY OF MUTANT P53 GENE-PRODUCT IN ARCHIVAL COLORECTAL NEOPLASMS	1	373
195	0	0	215 1994 FEB 13 JOURNAL OF CELLULAR BIOCHEMISTRY :163-163 PIETENPOL J; VOGELSTEIN B P53 FUNCTION AND DYSFUNCTION	0	0
196	9	23	211 1994 FEB [15] GENOMICS 19(3):525-531 CHO KR; OLINER JD; SIMONS JW; HEDRICK L; FEARON ER; et al. THE DCC GENE - STRUCTURAL-ANALYSIS AND MUTATIONS IN COLORECTAL CARCINOMAS	2	149
197	5	31	199 1994 MAR 1 CANCER RESEARCH 54(5):1169-1174 ELDEIRY WS; HARPER JW; OCONNOR PM; VELCULESCU VE; CANMAN CE; et al. WAF1/CIP1 IS INDUCED IN P53-MEDIATED G(1) ARREST AND APOPTOSIS	11	1538
198	3	43	214 1994 MAR [15] JOURNAL OF CELL BIOLOGY 124(6):1017-1027 PIERCEALL WE; CHO KR; GETZENBERG RH; REALE MA; HEDRICK L; et al. NIH3T3 CELLS EXPRESSING THE DELETED IN COLORECTAL-CANCER TUMOR-SUPPRESSOR GENE-PRODUCT STIMULATE NEURITE OUTGROWTH IN RAT PC12 PHEOCHROMOCYTOMA CELLS	1	43
199	5	32	224 1994 MAR 15 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91(6):1998-2002 PIETENPOL JA; TOKINO T; THIAGALINGAM S; ELDEIRY WS; KINZLER KW; et al. SEQUENCE-SPECIFIC TRANSCRIPTIONAL ACTIVATION IS ESSENTIAL FOR GROWTH SUPPRESSION BY P53	10	337
200	5	35	227 1994 MAR 18 SCIENCE 263(5153):1625-1629 PAPADOPOULOS N; NICOLAIDES NC; WEI YF; RUBEN SM; CARTER KC; et al. MUTATION OF A MUTL HOMOLOG IN HEREDITARY COLON-CANCER	26	1258
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201	9	35	225 1994 MAR 29 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91(7):2684-2688 CHEN CY; OLINER JD; ZHAN QM; FORNACE AJ; VOGELSTEIN B; et al. INTERACTIONS BETWEEN P53 AND MDM2 IN A MAMMALIAN-CELL CYCLE CHECKPOINT PATHWAY	1	253
202	5	26	200 1994 APR 1 CANCER RESEARCH 54(7):1645-1648 AALTONEN LA; PELTOMAKI P; MECKLIN JP; JARVINEN H; JASS JR; et al. REPLICATION ERRORS IN BENIGN AND MALIGNANT-TUMORS FROM HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER PATIENTS	11	406
203	7	27	210 1994 MAY 15 GENES & DEVELOPMENT 8(10):1174-1183 HEDRICK L; CHO KR; FEARON ER; WU TC; KINZLER KW; et al. THE DCC GENE-PRODUCT IN CELLULAR-DIFFERENTIATION AND COLORECTAL TUMORIGENESIS	0	129
204	13	32	208 1994 [JUN 30] COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 59:517-521 VOGELSTEIN B; KINZLER KW COLORECTAL-CANCER AND THE INTERSECTION BETWEEN BASIC AND CLINICAL RESEARCH	0	29
205	0	5	209 1994 [JUN 30] COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 59:585-587 LISITSYN NA; LEACH FS; VOGELSTEIN B; WIGLER MH DETECTION OF GENETIC LOSS IN TUMORS BY REPRESENTATIONAL DIFFERENCE ANALYSIS	1	9
206	3	27	216 1994 [JUN 30] JOURNAL OF NEURO-ONCOLOGY 20(1):55-58 ARTHUR RR; GROSSMAN SA; RONNETT BM; BIGNER SH; VOGELSTEIN B; et al. LACK OF ASSOCIATION OF HUMAN POLYOMAVIRUSES WITH HUMAN BRAIN-TUMORS	0	25
207	0	1	221 1994 JUL 7 NEW ENGLAND JOURNAL OF MEDICINE 331(1):49-50 KINZLER KW; VOGELSTEIN B CLINICAL IMPLICATIONS OF BASIC RESEARCH - CANCER-THERAPY MEETS P53	0	73
208	11	38	195 1994 JUL [15] AMERICAN JOURNAL OF PATHOLOGY 145(1):148-156 KIM HG; JEN J; VOGELSTEIN B; HAMILTON SR CLINICAL AND PATHOLOGICAL CHARACTERISTICS OF SPORADIC COLORECTAL CARCINOMAS WITH DNA-REPLICATION ERRORS IN MICROSATELLITE SEQUENCES	4	446
209	9	27	201 1994 JUL 15 CANCER RESEARCH 54(14):3672-3675 SMITH KJ; LEVY DB; MAUPIN P; POLLARD TD; VOGELSTEIN B; et al. WILD-TYPE BUT NOT MUTANT APC ASSOCIATES WITH THE MICROTUBULE CYTOSKELETON	8	230
210	4	33	202 1994 JUL 15 CANCER RESEARCH 54(14):3714-3717 PIETENPOL JA; PAPADOPOULOS N; MARKOWITZ S; WILLSON JKV; KINZLER KW; et al. PARADOXICAL INHIBITION OF SOLID TUMOR-CELL GROWTH BY BCL2	2	131
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211	1	15	219 1994 JUL 21 NATURE 370(6486):174-175 VOGELSTEIN B; KINZLER KW TUMOR-SUPPRESSOR GENES - X-RAYS STRIKE P53 AGAIN	0	44
212	13	57	222 1994 JUL 28 NEW ENGLAND JOURNAL OF MEDICINE 331(4):213-221 JEN J; KIM HG; PIANTADOSI S; LIU ZF; LEVITT RC; et al. ALLELIC LOSS OF CHROMOSOME 18Q AND PROGNOSIS IN COLORECTAL-CANCER	14	419
213	9	36	203 1994 SEP 1 CANCER RESEARCH 54(17):4590-4594 LIU B; PARSONS RE; HAMILTON SR; PETERSEN GM; LYNCH HT; et al. HMSH2 MUTATIONS IN HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER KINDREDS	12	327
214	7	29	220 1994 SEP 1 NATURE 371(6492):75-80 NICOLAIDES NC; PAPADOPOULOS N; LIU B; WEI YF; CARTER KC; et al. MUTATIONS OF 2 PMS HOMOLOGS IN HEREDITARY NONPOLYPOSIS COLON-CANCER	14	979
215	5	53	226 1994 SEP 13 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91(19):9009-9013 UEBA T; NOSAKA T; TAKAHASHI JA; SHIBATA F; FLORKIEWICZ RZ; et al. TRANSCRIPTIONAL REGULATION OF BASIC FIBROBLAST GROWTH-FACTOR GENE BY P53 IN HUMAN GLIOBLASTOMA AND HEPATOCELLULAR-CARCINOMA CELLS	0	104
216	10	32	212 1994 SEP [15] HUMAN MOLECULAR GENETICS 3(9):1537-1542 TOKINO T; THIAGALINGAM S; ELDEIRY WS; WALDMAN T; KINZLER KW; et al. P53 TAGGED SITES FROM HUMAN GENOMIC DNA	1	102
217	3	16	218 1994 SEP 21 JOURNAL OF THE NATIONAL CANCER INSTITUTE 86(18):1417-1419 LYNCH HT; DROUHARD T; LANSPA S; SMYRK T; LYNCH P; et al. MUTATION OF AN MUTL HOMOLOG IN A NAVAJO FAMILY WITH HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER	0	16
218	0	21	207 1994 OCT 7 CELL 79(1):1-3 VOGELSTEIN B; KINZLER KW HAS THE BREAST-CANCER GENE BEEN FOUND	0	43
219	5	36	194 1994 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 55(4):659-665 NYSTROMLAHTI M; PARSONS R; SISTONEN P; PYLKKANEN L; AALTONEN LA; et al. MISMATCH REPAIR GENES ON CHROMOSOMES 2P AND 3P ACCOUNT FOR A MAJOR SHARE OF HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER FAMILIES EVALUABLE BY LINKAGE	3	109
220	6	23	204 1994 NOV 1 CANCER RESEARCH 54(21):5523-5526 JEN J; POWELL SM; PAPADOPOULOS N; SMITH KJ; HAMILTON SR; et al. MOLECULAR DETERMINANTS OF DYSPLASIA IN COLORECTAL LESIONS	12	308
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221	0	0	196 1994 NOV 15 BLOOD 84(10):A292-A292 SATO Y; SUTO Y; PIETENPOL J; GOLUB TR; GILLILAND DG; et al. TEL AND THE GENE FOR P27KIP1 ARE FREQUENTLY DEPLETED IN PATIENTS WITH 12P13 REARRANGEMENTS AND HEMATOPOIETIC MALIGNANCIES	0	5
222	0	0	197 1994 NOV 15 BLOOD 84(10):A613-A613 SHIOHARA M; ELDIERY WS; WADA M; NAKAMAKI T; TAKEUCHI S; et al. ABSENCE OF WAF1 MUTATIONS IN A VARIETY OF HUMAN MALIGNANCIES	0	0
223	9	35	205 1994 NOV 15 CANCER RESEARCH 54(22):5953-5958 LEVY DB; SMITH KJ; BEAZERBARCLAY Y; HAMILTON SR; VOGELSTEIN B; et al. INACTIVATION OF BOTH APC ALLELES IN HUMAN AND MOUSE-TUMORS	5	152
224	1	1	213 1994 NOV [15] HUMAN MOLECULAR GENETICS 3(11):2082-2082 LEACH FS; NICOLAIDES NC; SISTONEN P; YU JW; KAO FT; et al. 3 DINUCLEOTIDE REPEAT POLYMORPHISMS PROXIMAL TO THE D2S123 LOCUS	0	7
225	7	46	198 1994 DEC 1 BLOOD 84(11):3781-3784 SHIOHARA M; ELDEIRY WS; WADA M; NAKAMAKI T; TAKEUCHI S; et al. ABSENCE OF WAF1 MUTATIONS IN A VARIETY OF HUMAN MALIGNANCIES	1	294
226	1	3	223 1994 DEC 8 NEW ENGLAND JOURNAL OF MEDICINE 331(23):1592-1592 HAMILTON SR; JEN J; VOGELSTEIN B ALLELES LOST AND GAINED IN MALIGNANT-CELLS - REPLY	0	0
227	3	41	206 1994 DEC 15 CANCER RESEARCH 54(24):6353-6358 JEN J; HARPER JW; BIGNER SH; BIGNER DD; PAPADOPOULOS N; et al. DELETION OF P16 AND P15 GENES IN BRAIN-TUMORS	3	400
228	5	30	251 1995 JAN 5 ONCOGENE 10(1):33-37 ESHLEMAN JR; LANG EZ; BOWERFIND GK; PARSONS R; VOGELSTEIN B; et al. INCREASED MUTATION-RATE AT THE HPRT LOCUS ACCOMPANIES MICROSATELLITE INSTABILITY IN COLON-CANCER	9	171
229	3	14	246 1995 JAN [15] NATURE GENETICS 9(1):10-11 DACOSTA LT; LIU B; ELDEIRY WS; HAMILTON SR; KINZLER KW; et al. POLYMERASE-DELTA VARIANTS IN RER COLORECTAL TUMORS	3	99
230	10	37	247 1995 JAN [15] NATURE GENETICS 9(1):48-55 LIU B; NICOLAIDES NC; MARKOWITZ S; WILLSON JKV; PARSONS RE; et al. MISMATCH REPAIR GENE DEFECTS IN SPORADIC COLORECTAL CANCERS WITH MICROSATELLITE INSTABILITY	15	567
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231	0	0	244 1995 FEB [15] JOURNAL OF MEDICAL GENETICS 32(2):146-146 FROGGATT NJ; KOCH DJ; DAVIES R; EVANS DGR; PARSONS R; et al. MOLECULAR-GENETIC ANALYSIS OF HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER SYNDROME	0	0
232	6	36	229 1995 MAR 15 CANCER RESEARCH 55(6):1206-1210 PIETENPOL JA; BOHLANDER SK; SATO Y; PAPADOPOULOS N; LIU B; et al. ASSIGNMENT OF THE HUMAN P27(KIP1) GENE TO 12P13 AND ITS ANALYSIS IN LEUKEMIAS	1	194
233	0	0	253 1995 MAR 17 SCIENCE 267(5204):1609-1618 WEINTRAUB H; ASHBURNER M; GOODFELLOW PN; LODISH HF; ARNTZEN CJ; et al. THROUGH THE GLASS LIGHTLY	0	2
234	15	72	250 1995 MAR 30 NEW ENGLAND JOURNAL OF MEDICINE 332(13):839-847 HAMILTON SR; LIU B; PARSONS RE; PAPADOPOULOS N; JEN J; et al. THE MOLECULAR-BASIS OF TURCOTS-SYNDROME	5	345
235	0	0	238 1995 APR [15] GASTROENTEROLOGY 108(4):A478-A478 HAMILTON SR; LIU B; PARSONS RE; PAPADOPOLOUS NC; JEN J; et al. THE MOLECULAR-BASIS OF TURCOT SYNDROME	0	0
236	0	0	239 1995 APR [15] GASTROENTEROLOGY 108(4):A520-A520 OLSCHWANG S; LAURENTPUIG P; BOISSON C; VOGELSTEIN B; THOMAS G HMSH2 GERMLINE MUTATIONS SCREENING IN 50 FAMILIAL CANCER AGGREGATIONS	0	1
237	2	39	240 1995 APR 15 GENES & DEVELOPMENT 9(8):935-944 MACLEOD KF; SHERRY N; HANNON G; BEACH D; TOKINO T; et al. P53-DEPENDENT AND INDEPENDENT EXPRESSION OF P21 DURING CELL-GROWTH, DIFFERENTIATION, AND DNA-DAMAGE	2	609
238	0	0	237 1995 APR 24 FASEB JOURNAL 9(6):A1258-A1258 NICOLAIDES NC; KINZLER KW; VOGELSTEIN B MUTATIONS OF MISMATCH REPAIR GENES IN HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER	0	0
239	11	33	254 1995 MAY 5 SCIENCE 268(5211):738-740 PARSONS R; LI GM; LONGLEY M; MODRICH P; LIU B; et al. MISMATCH REPAIR DEFICIENCY IN PHENOTYPICALLY NORMAL HUMAN-CELLS	3	241
240	7	42	243 1995 MAY [15] INTERNATIONAL JOURNAL OF ONCOLOGY 6(5):937-946 ZHAN QM; ELDEIRY W; BAE I; ALAMO I; KASTAN MB; et al. SIMILARITY OF THE DNA-DAMAGE RESPONSIVENESS AND GROWTH-SUPPRESSIVE PROPERTIES OF WAF1/CIP1 AND GADD45	0	43
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241	6	36	255 1995 JUN 2 SCIENCE 268(5215):1336-1338 MARKOWITZ S; WANG J; MYEROFF L; PARSONS R; SUN LZ; et al. INACTIVATION OF THE TYPE-II TGF-BETA RECEPTOR IN COLON-CANCER CELLS WITH MICROSATELLITE INSTABILITY	20	1336
242	9	37	252 1995 JUN 20 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92(13):6062-6066 THIAGALINGAM S; KINZLER KW; VOGELSTEIN B PAK1, A GENE THAT CAN REGULATE P53 ACTIVITY IN YEAST	0	20
243	0	0	245 1995 JUN 21 JOURNAL OF THE NATIONAL CANCER INSTITUTE 87(12):877-883 BISHOP JM; CALABRESI P; ANTMAN K; BALTIMORE D; FOLKMAN J; et al. NCI INTRAMURAL PROGRAM REVIEW COMPLETE - PUBLIC COMMENT SOUGHT ON RECOMMENDATIONS	0	0
244	4	22	236 1995 [JUN 30] CYTOGENETICS AND CELL GENETICS 71(4):343-344 TRENT JM; WILTSHIRE R; SU LK; NICOLAIDES NC; VOGELSTEIN B; et al. THE GENE FOR THE APC-BINDING PROTEIN BETA-CATENIN (CTNNB1) MAPS TO CHROMOSOME 3P22, A REGION FREQUENTLY ALTERED IN HUMAN MALIGNANCIES	0	17
245	7	27	256 1995 JUN 30 SCIENCE 268(5219):1915-1917 PAPADOPOULOS N; NICOLAIDES NC; LIU B; PARSONS R; LENGAUER C; et al. MUTATIONS OF GTBP IN GENETICALLY UNSTABLE CELLS	9	385
246	13	58	230 1995 JUL 1 CANCER RESEARCH 55(13):2910-2919 ELDEIRY WS; TOKINO T; WALDMAN T; OLINER JD; VELCULESCU VE; et al. TOPOLOGICAL CONTROL OF P21(WAF1/CIP1) EXPRESSION IN NORMAL AND NEOPLASTIC TISSUES	5	441
247	10	33	231 1995 JUL 15 CANCER RESEARCH 55(14):2972-2977 SU LK; BURRELL M; HILL DE; GYURIS J; BRENT R; et al. APC BINDS TO THE NOVEL PROTEIN EB1	5	185
248	0	36	228 1995 AUG 15 BLOOD 86(4):1525-1533 SATO Y; SUTO Y; PIETENPOL J; GOLUB TR; GILLILAND DG; et al. TEL AND KIP1 DEFINE THE SMALLEST REGION OF DELETIONS ON 12P13 IN HEMATOPOIETIC MALIGNANCIES	0	77
249	5	24	248 1995 SEP [15] NATURE GENETICS 11(1):99-102 PAPADOPOULOS N; LEACH FS; KINZLER KW; VOGELSTEIN B MONOALLELIC MUTATION ANALYSIS (MAMA) FOR IDENTIFYING GERMLINE MUTATIONS	3	38
250	6	23	241 1995 SEP 20 GENOMICS 29(2):329-334 NICOLAIDES NC; KINZLER KW; VOGELSTEIN B ANALYSIS OF THE 5'-REGION OF PMS2 REVEALS HETEROGENEOUS TRANSCRIPTS AND A NOVEL OVERLAPPING GENE	3	20
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251	1	16	257 1995 OCT 20 SCIENCE 270(5235):484-487 VELCULESCU VE; ZHANG L; VOGELSTEIN B; KINZLER KW SERIAL ANALYSIS OF GENE-EXPRESSION	18	1504
252	7	24	232 1995 NOV 15 CANCER RESEARCH 55(22):5184-5186 RIGGINS GJ; MARKOWITZ S; WILSON JK; VOGELSTEIN B; KINZLER KW ABSENCE OF SECRETORY PHOSPHOLIPASE A(2) GENE ALTERATIONS IN HUMAN COLORECTAL-CANCER	3	51
253	7	36	233 1995 NOV 15 CANCER RESEARCH 55(22):5187-5190 WALDMAN T; KINZLER KW; VOGELSTEIN B P21 IS NECESSARY FOR THE P53-MEDIATED G(1) ARREST IN HUMAN CANCER-CELLS	20	566
254	6	20	249 1995 NOV [15] NATURE MEDICINE 1(11):1203-1206 NYSTROMLAHTI M; KRISTO P; NICOLAIDES NC; CHANG SY; AALTONEN LA; et al. FOUNDING MUTATIONS AND ALU-MEDIATED RECOMBINATION IN HEREDITARY COLON-CANCER	1	147
255	6	23	242 1995 NOV 20 GENOMICS 30(2):195-206 NICOLAIDES NC; CARTER KC; SHELL BK; PAPADOPOULOS N; VOGELSTEIN B; et al. GENOMIC ORGANIZATION OF THE HUMAN PMS2 GENE FAMILY	2	45
256	2	25	234 1995 DEC 1 CANCER RESEARCH 55(23):5545-5547 MYEROFF LL; PARSONS R; KIM SJ; HEDRICK L; CHO KR; et al. A TRANSFORMING GROWTH-FACTOR-BETA RECEPTOR-TYPE-II GENE MUTATION COMMON IN COLON AND GASTRIC BUT RARE IN ENDOMETRIAL CANCERS WITH MICROSATELLITE INSTABILITY	2	347
257	9	24	235 1995 DEC 1 CANCER RESEARCH 55(23):5548-5550 PARSONS R; MYEROFF LL; LIU B; WILLSON JKV; MARKOWITZ SD; et al. MICROSATELLITE INSTABILITY AND MUTATIONS OF THE TRANSFORMING GROWTH-FACTOR-BETA TYPE-II RECEPTOR GENE IN COLORECTAL-CANCER	17	544
258	1	20	269 1996 JAN 4 NATURE 379(6560):19-20 Kinzler KW; Vogelstein B Life (and death) in a malignant tumour	1	133
259	10	25	259 1996 JAN 15 CANCER RESEARCH 56(2):235-240 Leach FS; Polyak K; Burrell M; Johnson KA; Hill D; et al. Expression of the human mismatch repair gene hMSH2 in normal and neoplastic tissues	3	107
260	0	0	268 1996 JAN [15] LABORATORY INVESTIGATION 74(1):895-895 Bennett WP; ElDeiry WS; Guinee DG; Caporaso NE; Welsh JA; et al. p53/p21((waf1/cip1)) expression in human lung cancer	0	0
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261	5	13	267 1996 FEB 1 GENOMICS 31(3):395-397 Nicolaides NC; Palombo F; Kinzler KW; Vogelstein B; Jiricny J Molecular cloning of the N-terminus of GTBP	1	23
262	16	36	274 1996 FEB [15] NATURE MEDICINE 2(2):169-174 Liu B; Parsons R; Papadopoulos N; Nicolaides NC; Lynch HT; et al. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients	10	559
263	4	41	275 1996 APR 30 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(9):4192-4196 DaCosta LT; Jen J; He TC; Chan TA; Kinzler KW; et al. Converting cancer genes into killer genes	1	32
264	3	28	270 1996 JUN 20 NATURE 381(6584):713-716 Waldman T; Lengauer C; Kinzler KW; Vogelstein B Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21	15	482
265	7	37	260 1996 JUL 1 CANCER RESEARCH 56(13):2936-2939 Thiagalingam S; Lisitsyn NA; Hamaguchi M; Wigler MH; Willson JKV; et al. Evaluation of the FHIT gene in colorectal cancers	1	110
266	10	32	272 1996 JUL [15] NATURE GENETICS 13(3):343-346 Thiagalingam S; Lengauer C; Leach FS; Schutte M; Hahn SA; et al. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers	14	303
267	4	26	273 1996 JUL [15] NATURE GENETICS 13(3):347-349 Riggins GJ; Thiagalingam S; Rozenblum E; Weinstein CL; Kern SE; et al. Mad-related genes in the human	12	278
268	13	46	276 1996 JUL 23 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(15):7950-7954 Morin PJ; Vogelstein B; Kinzler KW Apoptosis and APC in colorectal tumorigenesis	9	261
269	7	36	265 1996 AUG 1 GENES & DEVELOPMENT 10(15):1945-1952 Polyak K; Waldman T; He TC; Kinzler KW; Vogelstein B Genetic determinants of p53-induced apoptosis and growth arrest	8	331
270	5	38	277 1996 AUG 6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(16):8390-8394 Pietenpol JA; Lengauer C; Jordan J; Kinzler KW; Vogelstein B Mammalian cells resistant to tumor suppressor genes	0	7
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271	11	40	258 1996 AUG [15] AMERICAN JOURNAL OF PATHOLOGY 149(2):381-387 Polyak K; Hamilton SR; Vogelstein B; Kinzler KW Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia	1	60
272	6	41	261 1996 AUG [15] CARCINOGENESIS 17(8):1757-1760 BeazerBarclay Y; Levy DB; Moser AR; Dove WF; Hamilton SR; et al. Sulindac suppresses tumorigenesis in the Min mouse	2	102
273	21	55	278 1996 AUG 20 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(17):9049-9054 Huang J; Papadopoulos N; McKinley AJ; Farrington SM; Curtis LJ; et al. APC mutations in colorectal tumors with mismatch repair deficiency	11	202
274	0	13	271 1996 AUG 22 NATURE 382(6593):672-672 Kunzler KW; Vogelstein B Breast cancer - What's mice got to do with it?	0	0
275	9	57	264 1996 OCT [15] CYTOPATHOLOGY 7(5):340-351 Dowell SP; McGoogan E; Picksley SM; ElDeiry WS; Vogelstein B; et al. Expression of p21(waf1/Cip1), MDM2 and p53 in vivo: Analysis of cytological preparations	0	3
276	27	96	262 1996 OCT 18 CELL 87(2):159-170 Kinzler KW; Vogelstein B Lessons from hereditary colorectal cancer	28	1767
277	0	2	263 1996 OCT 18 CELL 87(2):173-173 Derynck R; Gelbart WM; Harland RM; Heldin CH; Kern SE; et al. Nomenclature: Vertebrate mediators of TGF beta family signals	2	97
278	1	1	266 1996 NOV 1 GENES & DEVELOPMENT 10(21):2818-2818 Polyak K; Waldman T; He TC; Kinzler KW; Vogelstein B Genetic determinants of p53-induced apoptosis and growth arrest (vol 10, pg 1945, 1996)	0	0
279	7	30	284 1997 JAN [15] HUMAN MOLECULAR GENETICS 6(1):105-110 Dunlop MG; Farrington SM; Carothers AD; Wyllie AH; Sharp L; et al. Cancer risk associated with germline DNA mismatch repair gene mutations	0	168
280	0	0	285 1997 JAN [15] LABORATORY INVESTIGATION 76(1):946-946 Burke L; Freedman A; ElDeiry W; Bennett W; Guinee D; et al. Cyclin D1, p53 and p21(waf1/cip1) expression predict survival in non-small cell lung cancer (NSCLC).	0	0
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281	2	34	282 1997 JAN 24 CELL 88(2):243-251 Velculescu VE; Zhang L; Zhou W; Vogelstein J; Basrai MA; et al. Characterization of the yeast transcriptome	7	480
282	8	50	292 1997 MAR 18 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(6):2545-2550 Lengauer C; Kinzler KW; Vogelstein B DNA methylation and genetic instability in colorectal cancer cells	3	184
283	3	22	293 1997 MAR 21 SCIENCE 275(5307):1784-1787 Korinek V; Barker N; Morin PJ; vanWichen D; deWeger R; et al. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC(-/-) colon carcinoma	9	1107
284	13	37	294 1997 MAR 21 SCIENCE 275(5307):1787-1790 Morin PJ; Sparks AB; Korinek V; Barker N; Clevers H; et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC	12	1342
285	5	29	287 1997 APR 10 NATURE 386(6625):623-627 Lengauer C; Kinzler KW; Vogelstein B Genetic instability in colorectal cancers	25	588
286	1	20	283 1997 APR [15] CELL DEATH AND DIFFERENTIATION 4(3):242-246 Polyak K; Wu TT; Hamilton SR; Kinzler KW; Vogelstein B Less death in the dying	0	6
287	1	12	288 1997 APR 24 NATURE 386(6627):761-& Kinzler KW; Vogelstein B Cancer-susceptibility genes - Gatekeepers and caretakers	0	447
288	3	34	295 1997 MAY 23 SCIENCE 276(5316):1268-1272 Zhang L; Zhou W; Velculescu VE; Kern SE; Hruban RH; et al. Gene expression profiles in normal and cancer cells	12	700
289	6	19	281 1997 JUL 1 CANCER RESEARCH 57(13):2578-2580 Riggins GJ; Kinzler KW; Vogelstein B; Thiagalingam S Frequency of Smad gene mutations in human cancers	8	168
290	5	25	290 1997 SEP [15] NATURE GENETICS 17(1):79-83 Laken SJ; Petersen GM; Gruber SB; Oddoux C; Ostrer H; et al. Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC	2	304
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291	4	17	291 1997 SEP [15] NATURE MEDICINE 3(9):1034-1036 Waldman T; Zhang YG; Dillehay L; Yu J; Kinzler K; et al. Cell-cycle arrest versus cell death in cancer therapy	2	212
292	5	29	289 1997 SEP 18 NATURE 389(6648):300-305 Polyak K; Xia Y; Zweier JL; Kinzler KW; Vogelstein B A model for p53-induced apoptosis	12	1126
293	0	0	279 1997 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 61(4):A36-A36 Velculescu VE; Zhang L; Zhou W; Polyak K; Basrai M; et al. Serial analysis of gene expression (SAGE).	0	0
294	0	0	280 1997 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 61(4):A89-A89 Zhang L; Zhou W; Velculescu VE; Kern SE; Hruban RH; et al. Gene expression: a looking glass for cancer	0	0
295	9	38	286 1997 DEC [15] MOLECULAR CELL 1(1):3-11 Hermeking H; Lengauer C; Polyak K; He TC; Zhang L; et al. 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression	11	485
296	4	43	310 1998 JAN 20 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(2):681-686 Chan TA; Morin PJ; Vogelstein B; Kinzler KW Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis	3	311
297	5	26	297 1998 FEB [15] CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 7(2):109-112 Zhou W; Sokoll LJ; Bruzek DJ; Zhang L; Velculescu VE; et al. Identifying markers for pancreatic cancer by gene expression analysis	2	50
298	7	56	311 1998 MAR 3 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(5):2412-2416 Zhou SB; Buckhaults P; Zawel L; Bunz F; Riggins G; et al. Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells	5	68
299	1	25	312 1998 MAR 3 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(5):2509-2514 He TC; Zhou SB; da Costa LT; Yu J; Kinzler KW; et al. A simplified system for generating recombinant adenoviruses	9	1064
300	11	32	298 1998 MAR 15 CANCER RESEARCH 58(6):1130-1134 Sparks AB; Morin PJ; Vogelstein B; Kinzler KW Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer	10	411
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301	10	30	301 1998 MAR [15] MOLECULAR AND CELLULAR BIOLOGY 18(3):1635-1641 Nicolaides NC; Littman SJ; Modrich P; Kinzler KW; Vogelstein B A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype	0	43
302	7	39	304 1998 MAR [15] MOLECULAR CELL 1(4):611-617 Zawel L; Dai JL; Buckhaults P; Zhou SB; Kinzler KW; et al. Human Smad3 and Smad4 are sequence-specific transcription activators	6	399
303	8	29	306 1998 MAR 19 NATURE 392(6673):300-303 Cahill DP; Lengauer C; Yu J; Riggins GJ; Willson JKV; et al. Mutations of mitotic checkpoint genes in human cancers	17	613
304	0	0	300 1998 APR 15 GASTROENTEROLOGY 114(4):A651-A651 Nagaba Y; Zhang L; Vogelstein B; Cross H; Guggino S mRNA expression of L-type calcium channels increases in colon cancer.	0	1
305	1	12	314 1998 MAY 15 SCIENCE 280(5366):1036-1037 Kinzler KW; Vogelstein B Landscaping the cancer terrain	1	189
306	5	31	313 1998 JUN 9 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(12):6870-6875 Herman JG; Umar A; Polyak K; Graff JR; Ahuja N; et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma	2	619
307	8	36	305 1998 JUL [15] MOLECULAR CELL 2(1):121-127 Zhou S; Zawel L; Lengauer C; Kinzler KW; Vogelstein B Characterization of human FAST-1, a TGF beta and activin signal transducer	0	135
308	10	40	315 1998 SEP 4 SCIENCE 281(5382):1509-1512 He TC; Sparks AB; Rago C; Hermeking H; Zawel L; et al. Identification of c-MYC as a target of the APC pathway	11	1184
309	15	120	296 1998 OCT [15] AMERICAN JOURNAL OF PATHOLOGY 153(4):1063-1078 Fujiwara T; Stolker JM; Watanabe T; Rashid A; Longo P; et al. Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences	0	90
310	0	0	302 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9:41A-41A Cahill DP; Kinzler KW; Vogelstein B; Lengauer C Mitotic checkpoint genes and chromosomal instability in cancer	0	0
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311	0	0	303 1998 NOV [15] MOLECULAR BIOLOGY OF THE CELL 9:381A-381A He TC; Kinzler KW; Vogelstein B Identification of downstream targets in APC/beta-catenin-Tcf4 pathway	0	0
312	3	32	309 1998 NOV [15] NATURE GENETICS 20(3):291-293 Polyak K; Li YB; Zhu H; Lengauer C; Willson JKV; et al. Somatic mutations of the mitochondrial genome in human colorectal tumours	0	208
313	8	48	316 1998 NOV 20 SCIENCE 282(5393):1497-1501 Bunz F; Dutriaux A; Lengauer C; Waldman T; Zhou S; et al. Requirement for p53 and p21 to sustain G(2) arrest after DNA damage	16	670
314	5	25	299 1998 DEC 1 CANCER RESEARCH 58(23):5267-5270 Gruber SB; Entius MM; Petersen GM; Laken SJ; Longo PA; et al. Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome	0	58
315	4	27	308 1998 DEC [15] NATURE BIOTECHNOLOGY 16(13):1352-1356 Laken SJ; Jackson PE; Kinzler KW; Vogelstein B; Strickland PT; et al. Genotyping by mass spectrometric analysis of short DNA fragments	3	67
316	11	92	307 1998 DEC 17 NATURE 396(6712):643-649 Lengauer C; Kinzler KW; Vogelstein B Genetic instabilities in human cancers	16	1139
317	0	0	317 1999 JAN [15] BIOPHYSICAL JOURNAL 76(1):A135-A135 Vogelstein B Genetic instabilities in human cancers	0	0
318	6	29	318 1999 JAN 15 CANCER RESEARCH 59(2):320-324 Grady WM; Myeroff LL; Swinler SE; Rajput A; Thiagalingam S; et al. Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers	4	117
319	1	13	321 1999 JAN [15] GASTROENTEROLOGY 116(1):210-212 Gruber SB; Petersen GM; Kinzler KW; Vogelstein B Cancer, crash sites, and the new genetics of neoplasia	0	11
320	0	0	324 1999 JAN [15] JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS 188(1):74-79 Vogelstein B Familial colon cancer	0	2
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321	10	41	330 1999 MAR 2 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(5):2322-2326 Laken SJ; Papadopoulos N; Petersen GM; Gruber SB; Hamilton SR; et al. Analysis of masked mutations in familial adenomatous polyposis	1	49
322	3	35	322 1999 JUN 1 GENOMICS 58(2):181-187 Cahill DP; da Costa LT; Carson-Walter EB; Kinzler KW; Vogelstein B; et al. Characterization of MAD2B and other mitotic spindle checkpoint genes	0	80
323	7	56	331 1999 AUG 3 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(16):9236-9241 Vogelstein B; Kinzler KW Digital PCR	6	57
324	6	33	323 1999 AUG [15] JOURNAL OF CLINICAL INVESTIGATION 104(3):263-269 Bunz F; Hwang PM; Torrance C; Waldman T; Zhang YG; et al. Disruption of p53 in human cancer cells alters the responses to therapeutic agents	7	299
325	12	27	329 1999 SEP 2 ONCOGENE 18(35):5010-5014 da Costa LT; He TC; Yu J; Sparks AB; Morin PJ; et al. CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling	1	46
326	5	20	326 1999 OCT 7 NATURE 401(6753):616-620 Chan TA; Hermeking H; Lengauer C; Kinzler KW; Vogelstein B 14-3-3 sigma is required to prevent mitotic catastrophe after DNA damage	9	324
327	2	8	328 1999 OCT 7 NEW ENGLAND JOURNAL OF MEDICINE 341(15):1144-1146 Zhou SB; Kinzler KW; Vogelstein B Going mad with Smads	0	16
328	9	61	320 1999 OCT 29 CELL 99(3):335-345 He TC; Chan TA; Vogelstein B; Kinzler KW PPAR delta is an APC-regulated target of nonsteroidal anti-inflammatory drugs	4	446
329	7	20	319 1999 NOV 1 CANCER RESEARCH 59(21):5403-5407 Lal A; Lash AE; Altschul SF; Velculescu V; Zhang L; et al. A public database for gene expression in human cancers	3	172
330	0	0	325 1999 NOV [15] MOLECULAR BIOLOGY OF THE CELL 10:351A-351A Vogelstein B; Kinzler KW Gatekeepers and caretakers	0	0
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331	9	31	332 1999 DEC 7 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(25):14517-14522 Yu J; Zhang L; Hwang PM; Rago C; Kinzler KW; et al. Identification and classification of p53-regulated genes	6	198
332	6	11	327 1999 DEC [15] NATURE GENETICS 23(4):387-388 Velculescu VE; Madden SL; Zhang L; Lash AE; Yu J; et al. Analysis of human transcriptomes	6	224
333	14	46	334 1999 DEC [15] TRENDS IN BIOCHEMICAL SCIENCES 24(12):M57-M60 Cahill DP; Kinzler KW; Vogelstein B; Lengauer C Genetic instability and darwinian selection in tumours	0	5
334	15	47	335 1999 DEC [15] TRENDS IN CELL BIOLOGY 9(12):M57-M60 Cahill DP; Kinzler KW; Vogelstein B; Lengauer C Genetic instability and darwinian selection in tumours (Reprinted from Trends in Biochemical Science, vol 12, Dec., 1999)	0	70
335	15	47	336 1999 DEC [15] TRENDS IN GENETICS 15(12):M57-M60 Cahill DP; Kinzler KW; Vogelstein B; Lengauer C Genetic instability and darwinian selection in tumours (Reprinted from Trends in Biochemical Sciences, vol 12, Dec., 1999)	0	4
336	0	0	333 1999 DEC 17 SCIENCE 286(5448):2300-2301 Vogelstein JT; Vogelstein JV; Vogelstein B Testing the effects of genetic variations using MINIME technology.	0	0
337	3	15	340 2000 FEB 17 NATURE 403(6771):723-724 Yan H; Papadopoulos N; Marra G; Perrera C; Jiricny J; et al. Conversion of diploidy to haploidy - Individuals susceptible to multigene disorders may now be spotted more easily.	5	108
338	4	40	345 2000 FEB 29 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(5):2229-2234 Hermeking H; Rago C; Schuhmacher M; Li Q; Barrett JF; et al. Identification of CDK4 as a target of c-MYC	0	115
339	10	42	338 2000 MAR 15 CANCER RESEARCH 60(6):1671-1676 Shih IM; Tu J; He TC; Vogelstein B; Kinzler KW The beta-catenin binding domain of adenomatous polyposis coil is sufficient for tumor suppression	1	57
340	4	30	341 2000 APR 27 NATURE 404(6781):1003-1007 Rhee I; Jair KW; Yen RWC; Lengauer C; Herman JG; et al. CpG methylation is maintained in human cancer cells lacking DNMT1	3	93
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341	0	25	343 2000 JUN [15] NATURE MEDICINE 6(6):711-714 Shih IM; Torrance C; Sokoll LJ; Chan DW; Kinzler KW; et al. Assessing tumors in living animals through measurement of urinary beta-human chorionic gonadotropin	0	8
342	14	31	339 2000 JUL 1 GENES & DEVELOPMENT 14(13):1584-1588 Chan TA; Hwang PM; Hermeking H; Kinzler KW; Vogelstein B Cooperative effects of genes controlling the G(2)/M checkpoint	3	101
343	7	37	337 2000 AUG 1 CANCER LETTERS 156(1):63-72 Flatt PM; Polyak K; Tang LJ; Scatena CD; Westfall MD; et al. p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest	0	21
344	3	32	346 2000 AUG 18 SCIENCE 289(5482):1197-1202 St Croix B; Rago C; Velculescu V; Traverso G; Romans KE; et al. Genes expressed in human tumor endothelium	7	425
345	5	50	344 2000 SEP [15] NATURE MEDICINE 6(9):1024-1028 Torrance CJ; Jackson PE; Montgomery E; Kinzler KW; Vogelstein B; et al. Combinatorial chemoprevention of intestinal neoplasia	0	176
346	2	20	347 2000 SEP 15 SCIENCE 289(5486):1890-1892 Yen H; Kinzler KW; Vogelstein B Genetics - Genetic testing - Present and future	0	1
347	9	27	349 2000 OCT [15] TRENDS IN GENETICS 16(10):423-425 Velculescu VE; Vogelstein B; Kinzler KW Analysing uncharted transcriptomes with SAGE	1	83
348	4	23	348 2000 NOV 3 SCIENCE 290(5493):989-+ Zhang L; Yu J; Park BH; Kinzler KW; Vogelstein B Role of BAX in the apoptotic response to anticancer agents	3	236
349	2	41	342 2000 NOV 16 NATURE 408(6810):307-310 Vogelstein B; Lane D; Levine AJ Surfing the p53 network	10	844
350	3	18	352 2001 JAN 1 CANCER RESEARCH 61(1):33-35 Jackson PE; Qian GS; Friesen MD; Zhu YR; Lu PX; et al. Specific p53 mutations detected in plasma and tumors of hepatocellular carcinoma patients by electrospray ionization mass spectrometry	0	22
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351	7	42	353 2001 JAN 1 CANCER RESEARCH 61(1):256-260 Fink SP; Swinler SE; Lutterbaugh JD; Massague J; Thiagalingam S; et al. Transforming growth factor-beta-induced growth inhibition in a smad4 mutant colon adenoma cell line	1	33
352	4	20	364 2001 JAN [15] NATURE BIOTECHNOLOGY 19(1):78-81 Zhou W; Galizia G; Goodman SN; Romans KE; Kinzler KW; et al. Counting alleles reveals a connection between chromosome 18q loss and vascular invasion	4	21
353	10	39	354 2001 FEB 1 CANCER RESEARCH 61(3):818-822 Shih IM; Zhou W; Goodman SN; Lengauer C; Kinzler KW; et al. Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis	8	107
354	9	27	369 2001 FEB 27 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2598-2603 Park BH; Vogelstein B; Kinzler KW Genetic disruption of PPAR delta decreases the tumorigenicity of human colon cancer cells	1	69
355	6	27	370 2001 FEB 27 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2640-2645 Shih LM; Wang TL; Traverso G; Romans K; Hamilton SR; et al. Top-down morphogenesis of colorectal tumors	0	22
356	8	51	371 2001 FEB 27 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2698-2702 Thiagalingam S; Laken S; Willson JKV; Markowitz SD; Kinzler KW; et al. Mechanisms underlying losses of heterozygosity in human colorectal cancers	5	66
357	2	29	351 2001 MAR [15] CALCIFIED TISSUE INTERNATIONAL 68(3):151-155 Sparks AB; Peterson SN; Bell C; Loftus BJ; Hocking L; et al. Mutation screening of the TNFRSF11A gene encoding receptor activator of NF kappa B (RANK) in familial and sporadic Paget's disease of bone and osteosarcoma	0	19
358	16	54	362 2001 MAR [15] MOLECULAR CELL 7(3):673-682 Yu J; Zhang L; Hwang PM; Kinzler KW; Vogelstein B PUMA induces the rapid apoptosis of colorectal cancer cells	3	240
359	11	33	355 2001 MAY 1 CANCER RESEARCH 61(9):3801-3805 Zhang L; Yu J; Willson JKV; Markowitz SD; Kinzler KW; et al. Short mononucleotide repeat sequence variability in mismatch repair-deficient cancers	1	27
360	8	35	372 2001 MAY 8 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(10):5770-5775 Bardelli A; Cahill CP; Lederer G; Speicher MR; Kinzler KW; et al. Carcinogen-specific induction of genetic instability	3	56
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361	8	52	360 2001 MAY 18 CELL 105(4):445-457 Jallepalli PV; Waizenegger IC; Bunz F; Langer S; Speicher MR; et al. Securin is required for chromosomal stability in human cells	10	110
362	7	31	361 2001 JUN 6 JOURNAL OF THE NATIONAL CANCER INSTITUTE 93(11):858-865 Dong SM; Traverso G; Johnson C; Geng L; Favis R; et al. Detecting colorectal cancer in stool with the use of multiple genetic targets	2	97
363	2	30	366 2001 JUN [15] NATURE GENETICS 28(2):184-187 Howe JR; Bair JL; Sayed MG; Anderson ME; Mitros FA; et al. Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis	1	81
364	5	17	363 2001 AUG 30 NATURE 412(6850):865-866 Vogelstein B; Kinzler KW Achilles' heel of cancer?	0	21
365	1	35	356 2001 SEP 15 CANCER RESEARCH 61(18):6649-6655 Carson-Walter EB; Watkins DN; Nanda A; Vogelstein B; Kinzler KW; et al. Cell surface tumor endothelial markers are conserved in mice and humans	2	66
366	5	23	357 2001 OCT 1 CANCER RESEARCH 61(19):6996-7001 Buckhaults P; Rago C; St Croix B; Romans KE; Saha S; et al. Secreted and cell surface genes expressed in benign and malignant colorectal tumors	4	41
367	0	0	350 2001 OCT [15] AMERICAN JOURNAL OF HUMAN GENETICS 69(4):257-257 Wiesner GL; Daley D; Platzer P; Yan H; Ticknor C; et al. Common colon neoplasia is not linked to germline APC variants.	0	0
368	0	17	365 2001 OCT [15] NATURE BIOTECHNOLOGY 19(10):940-945 Torrance CJ; Agrawal V; Vogelstein B; Kinzler KW Use of isogenic human cancer cells for high-throughput screening and drug discovery	1	47
369	15	39	367 2001 OCT [15] NATURE MEDICINE 7(10):1111-1117 Hwang PM; Bunz F; Yu J; Rago C; Chan TA; et al. Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells	3	59
370	0	0	375 2001 OCT 15 SCIENTIST 15(20):6-6 Vogelstein B The science behind stem cell research	0	0
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371	2	15	358 2001 NOV 1 CANCER RESEARCH 61(21):7719-7721 Marra G; D'Atri S; Yan H; Perrera C; Cannavo E; et al. Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes	0	6
372	7	44	359 2001 NOV 1 CANCER RESEARCH 61(21):7798-7802 Liu T; Yan H; Kuismanen S; Percesepe A; Bisgaard ML; et al. The role of hPMS1 and hPMS2 in predisposing to colorectal cancer	0	34
373	6	24	374 2001 NOV 9 SCIENCE 294(5545):1343-1346 Saha S; Bardelli A; Buckhaults P; Velculescu VE; Rago C; et al. A phosphatase associated with metastasis of colorectal cancer	3	96
374	1	1	368 2001 NOV [15] NATURE MEDICINE 7(11):1255-1255 Hwang PM; Bunz F; Yu J; Rago C; Chan TA; et al. Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells (vol 7, pg 1111, 2001)	0	0
375	0	36	373 2001 DEC 18 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(26):15155-15160 Dang LH; Bettegowda C; Huso DL; Kinzler KW; Vogelstein B Combination bacteriolytic therapy for the treatment of experimental tumors	3	39
376	0	0	376 2002 JAN [15] ANNALS OF SURGICAL ONCOLOGY 9(1):S8-S9 Sayed MG; Ahmed AF; Anderson ME; Bair JL; Mitros FA; et al. The impact of germline SMAD4 or BMPR1A mutations on the phenotype of juvenile polyposis	0	0
377	5	10	387 2002 JAN [15] NATURE GENETICS 30(1):25-26 Yan H; Dobbie Z; Gruber SB; Markowitz S; Romans K; et al. Small changes in expression affect predisposition to tumorigenesis	2	59
378	7	30	382 2002 JAN 19 LANCET 359(9302):219-225 Zhou W; Goodman SN; Galizia G; Lieto E; Ferraraccio F; et al. Counting alleles to predict recurrence of early-stage colorectal cancers	0	38
379	6	47	388 2002 JAN 31 NEW ENGLAND JOURNAL OF MEDICINE 346(5):311-320 Traverso G; Shuber A; Levin B; Johnson C; Olsson L; et al. Detection of APC mutations in fecal DNA from patients with colorectal tumors	2	92
380	1	5	383 2002 FEB 2 LANCET 359(9304):403-404 Traverso G; Shuber A; Olsson L; Levin B; Johnson C; et al. Detection of proximal colorectal cancers through analysis of faecal DNA	1	43
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381	7	29	379 2002 FEB 15 CANCER RESEARCH 62(4):1129-1133 Bunz F; Fauth C; Speicher MR; Dutriaux A; Sedivy JM; et al. Targeted inactivation of p53 in human cells does not result in aneuploidy	1	42
382	0	3	395 2002 FEB 15 SCIENCE 295(5558):1237-1237 Vogelstein B; Alberts B; Shine K Genetics - Please don't call it cloning!	0	20
383	11	43	390 2002 MAR 5 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(5):2848-2853 Zawel L; Yu J; Torrance CJ; Markowitz S; Kinzler KW; et al. DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities	0	26
384	6	32	391 2002 MAR 5 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(5):3076-3080 Wang TL; Rago C; Silliman N; Ptak J; Markowitz S; et al. Prevalence of somatic alterations in the colorectal cancer cell genome	5	41
385	2	30	384 2002 APR 4 NATURE 416(6880):552-556 Rhee I; Bachman KE; Park BH; Jair KW; Yen RWC; et al. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells	1	131
386	4	19	386 2002 MAY [15] NATURE BIOTECHNOLOGY 20(5):508-512 Saha S; Sparks AB; Rago C; Akmaev V; Wang CJ; et al. Using the transcriptome to annotate the genome	1	107
387	12	53	392 2002 JUN 11 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(12):8265-8270 Chan TA; Wang ZH; Dang LH; Vogelstein B; Kinzler KW Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation	1	25
388	0	4	389 2002 JUN 13 NEW ENGLAND JOURNAL OF MEDICINE 346(24):1912-1913 Traverso G; Kinzler KW; Vogelstein B Fecal DNA tests for colorectal cancer - Reply	0	0
389	0	0	396 2002 JUL 5 SCIENCE 297(5578):52-52 Vogelstein B; Alberts B; Shine K Calling it something other than cloning - Response	0	0
390	1	17	380 2002 AUG 15 CANCER RESEARCH 62(16):4579-4582 Nakagawa H; Yan H; Lockman J; Hampel H; Kinzler KW; et al. Allele separation facilitates interpretation of potential splicing alterations and genomic rearrangements	0	16
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391	1	4	397 2002 AUG 16 SCIENCE 297(5584):1143-1143 Yan H; Yuan WS; Velculescu VE; Vogelstein B; Kinzler KW Allelic variation in human gene expression	1	116
392	4	9	385 2002 AUG 29 NATURE 418(6901):934-934 Rajagopalan H; Bardelli A; Lengauer C; Kinzler KW; Vogelstein B; et al. Tumorigenesis - RAF/RAS oncogenes and mismatch-repair status	3	117
393	1	38	377 2002 NOV [15] ANNALS OF SURGICAL ONCOLOGY 9(9):901-906 Sayed MG; Ahmed AF; Ringold JR; Anderson ME; Bair JL; et al. Germline SMAD4 or BMPR1A mutations and phenotype of juvenile polyposis	0	16
394	5	31	378 2002 NOV-DEC [NOV 15] CANCER BIOLOGY & THERAPY 1(6):685-692 Komarova NL; Lengauer C; Vogelstein B; Nowak MA Dynamics of genetic instability in sporadic and familial colorectal cancer	0	12
395	0	0	381 2002 NOV [15] EUROPEAN JOURNAL OF CANCER 38:S126-S126 Hallur Gurulingappa H; Buckhaults P; Kinzler KW; Vogelstein B; Khan SR Synthesis and evaluation of renal dipeptidase inhibitors as biomarkers for colon cancer	0	0
396	4	27	393 2002 DEC 10 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(25):16156-16161 Wang TL; Maierhofer C; Speicher MR; Lengauer C; Vogelstein B; et al. Digital karyotyping	2	19
397	6	36	394 2002 DEC 10 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(25):16226-16231 Nowak MA; Komarova NL; Sengupta A; Jallepalli PV; Shih IM; et al. The role of chromosomal instability in tumor initiation	3	63
398	3	3	407 2003 JAN 1 JOURNAL OF THE NATIONAL CANCER INSTITUTE 95(1):73-73 Jen J; Vogelstein B Tumor location and detection of K-Ras mutations in stool from colorectal cancer patients - Response	0	0
399	2	25	398 2003 JAN [15] CANCER CELL 3(1):89-95 Bachman KE; Park BH; Rhee I; Rajagopalan H; Herman JG; et al. Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene	0	55
400	12	47	410 2003 FEB 18 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(4):1931-1936 Yu J; Wang ZH; Kinzler KW; Vogelstein B; Zhang L PUMA mediates the apoptotic response to p53 in colorectal cancer cells	1	67
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401	1	14	414 2003 FEB 24 TETRAHEDRON LETTERS 44(9):1871-1873 Gurulingappa H; Buckhaults P; Kumar SK; Kinzler KW; Vogelstein B; et al. Design, synthesis and evaluation of new RDP inhibitors	1	3
402	7	50	399 2003 MAR 1 CANCER RESEARCH 63(5):994-999 Hempen PM; Zhang L; Bansal RK; Iacobuzio-Donahue CA; Murphy KM; et al. Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers	0	11
403	0	3	413 2003 MAY 9 SCIENCE 300(5621):949-949 Bardelli A; Parsons DW; Silliman N; Ptak J; Szabo S; et al. Mutational analysis of the tyrosine kinome in colorectal cancers	3	41
404	10	44	406 2003 JUN 6 JOURNAL OF BIOLOGICAL CHEMISTRY 278(23):20475-20479 Jallepalli PV; Lengauer C; Vogelstein B; Bunz F The Chk2 tumor suppressor is not required for p53 responses in human cancer cells	0	34
405	0	0	404 2003 JUN [15] DIABETES 52:A256-A256 Tsuchiya T; Yan H; Vogelstein B; Kinzler K; Bell G Identification of a haplotype associated with the decreased expression of calpain-10 in lymphoblastoid cell lines	0	0
406	2	34	402 2003 JUL [15] CLINICAL CANCER RESEARCH 9(7):2642-2650 Brown DA; Ward RL; Buckhaults P; Liu T; Romans KE; et al. MIC-1 serum level and genotype: Associations with progress and prognosis of colorectal carcinoma	1	3
407	5	29	411 2003 JUL 22 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(15):8817-8822 Dressman D; Yan H; Traverso G; Kinzler KW; Vogelstein B Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations	0	10
408	1	11	400 2003 SEP 1 CANCER RESEARCH 63(17):5234-5235 Wang ZH; Vogelstein B; Kinzler KW Phosphorylation of beta-catenin at S33, S37, or T41 can occur in the absence of phosphorylation at T45 in colon cancer cells	0	3
409	3	13	408 2003 SEP [15] NATURE BIOTECHNOLOGY 21(9):1093-1097 Traverso G; Diehl F; Hurst R; Shuber A; Whitney D; et al. Multicolor in vitro translation	0	3
410	14	59	409 2003 SEP [15] NATURE REVIEWS CANCER 3(9):695-701 Rajagopalan H; Nowak MA; Vogelstein B; Lengauer C The significance of unstable chromosomes in colorectal cancer	3	47
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411	6	22	403 2003 NOV 15 CLINICAL CANCER RESEARCH 9(15):5607-5615 Bardelli A; Saha S; Sager JA; Romans KE; Xin BZ; et al. PRL-3 expression in metastatic cancers	1	7
412	1	17	412 2003 DEC 9 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(25):15083-15088 Bettegowda C; Dang LH; Abrams R; Huson DL; Dillehay L; et al. Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria	1	2
413	6	27	401 2003 DEC 15 CANCER RESEARCH 63(24):8578-8581 Traverso G; Bettegowda C; Kraus J; Speicher MR; Kinzler KW; et al. Hyper-recombination and genetic instability in BLM-deficient epithelial cells	0	3
414	1	1	405 2003 DEC [15] GENES CHROMOSOMES & CANCER 38(4):329-329 Baker SJ; Kinzler KW; Vogelstein B Knudson's hypothesis and the TP53 revolution	0	1
415	3	20	427 2004 JAN [15] NUCLEIC ACIDS RESEARCH 32(1) Kohli M; Rago C; Lengauer C; Kinzler KW; Vogelstein B Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses	0	2
416	2	14	416 2004 FEB 1 CANCER RESEARCH 64(3):817-820 Nanda A; Carson-Walter EB; Seaman S; Barber TD; Stampfl J; et al. TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI)	1	5
417	6	41	429 2004 MAR 2 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(9):3089-3094 Wang TL; Diaz LA; Romans K; Bardelli A; Saha S; et al. Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients	0	6
418	9	28	423 2004 MAR 4 NATURE 428(6978):77-81 Rajagopalan H; Jallepalli PV; Rago C; Velculescu VE; Kinzler KW; et al. Inactivation of hCDC4 can cause chromosomal instability	1	29
419	4	43	422 2004 APR 1 CLINICAL CANCER RESEARCH 10(7):2386-2392 Koopmann J; Buckhaults P; Brown DA; Zahurak ML; Sato N; et al. Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers	0	1
420	2	13	424 2004 APR 1 NATURE 428(6982) Cummins JM; Rago C; Kohli M; Kinzler KW; Lengauer C; et al. Disruption of HAUSP gene stabilizes p53	0	0
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
421	0	0	428 2004 APR [15] PEDIATRIC RESEARCH 55(4):270A-271A Parsons DW; Bardelli A; Wang TL; Kinzler KW; Vogelstein B; et al. Mutational analysis of the protein kinome in colorectal cancer	0	0
422	1	4	432 2004 APR 23 SCIENCE 304(5670):554-554 Samuels Y; Wang ZH; Bardelli A; Silliman N; Ptak J; et al. High frequency of mutations of the PIK3CA gene in human cancers	0	33
423	5	30	417 2004 MAY 1 CANCER RESEARCH 64(9):2998-3001 Wang ZH; Cummins JM; Shen D; Cahill DP; Jallepalli PV; et al. Three classes of genes mutated in colorectal cancers with chromosomal instability	0	6
424	0	14	418 2004 MAY 1 CANCER RESEARCH 64(9):3006-3008 Cummins JM; Kohli M; Rago C; Kinzler KW; Vogelstein B; et al. X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells	1	5
425	5	28	433 2004 MAY 21 SCIENCE 304(5674):1164-1166 Wang ZH; Shen D; Parsons DW; Bardelli A; Sager J; et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers	0	9
426	2	19	421 2004 JUN [15] CELL CYCLE 3(6):689-692 Cummins JM; Vogelstein B HAUSP is required for p53 destabilization	0	0
427	2	18	415 2004 JUL 5 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14(13):3531-3533 Gurulingappa H; Buckhalts P; Kinzler KW; Vogelstein B; Khan SR Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase	0	0
428	7	118	425 2004 AUG [15] NATURE MEDICINE 10(8):789-799 Vogelstein B; Kinzler KW Cancer genes and the pathways they control	1	20
429	3	32	430 2004 OCT 19 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(42):15172-15177 Agrawal N; Bettegowda C; Cheong I; Geschwind JF; Drake CG; et al. Bacteriolytic therapy can generate a potent immune response against experimental tumors	1	1
430	5	37	431 2004 NOV 30 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(48):16897-16902 Kohli M; Yu J; Seaman C; Bardelli A; Kinzler KW; et al. SMAC/Diablo-dependent apoptosis induced by nonsteroidal anti inflammatory drugs (NSAIDs) in colon cancer cells	0	0
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
431	3	9	419 2004 DEC 1 CANCER RESEARCH 64(23):8507-8511 Nanda A; Buckhaults P; Seaman S; Agrawal N; Boutin P; et al. Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R	0	0
432	2	20	420 2004 DEC 15 CANCER RESEARCH 64(24):8816-8820 Bentires-Alj M; Paez JG; David FS; Keilhack H; Halmos B; et al. Activating mutations of the Noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia	0	1
433	0	5	426 2004 DEC 30 NEW ENGLAND JOURNAL OF MEDICINE 351(27):2883-2883 Barber TD; Vogelstein B; Kinzler KW; Velculescu VE Somatic mutations of EGFR in colorectal cancers and glioblastomas	0	0
434	2	28	434 2005 JAN 25 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(4):1145-1150 Bettegowda C; Foss CA; Cheong I; Wang YC; Diaz L; et al. Imaging bacterial infections with radiolabeled 1-(2 '-deoxy-2 '-fluoro-beta-D-arabinofuranosyl)-5-iodouracil	0	0
435	7	58	435 2005 FEB [15] SEMINARS IN CANCER BIOLOGY 15(1):43-49 Michor F; Iwasa Y; Vogelstein B; Lengauer C; Nowak MA Can chromosomal instability initiate tumorigenesis?	0	0

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