#	Cited nodes	Nodes / Authors	GCS	LCS
101	1	476 2001 NATURE 409(6822):853-855 Jimenez-Sanchez G; Childs B; Valle D Human disease genes	30	0
102	2	519 2001 NATURE GENETICS 29(4):459-464 Hodgson G; Hager JH; Volik S; Hariono S; Wernick M; Moore D; Albertson DG; Pinkel D; Collins C; Hanahan D; Gray JW Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas	30	5
103	2	530 2001 NATURE REVIEWS GENETICS 2(4):302-312 Kumar A; Snyder M Emerging technologies in yeast genomics	30	6
104	2	21 2001 ANALYTICAL CHEMISTRY 73(9):1917-1926 Shevchenko A; Sunyaev S; Loboda A; Shevehenko A; Bork P; Ens W; Standing KG Charting the proteomes of organisms with unsequenced genomes by MALDI-quadrupole time of flight mass spectrometry and BLAST homology searching	29	2
105	1	475 2001 NATURE 409(6822):850-852 Futreal PA; Kasprzyk A; Birney E; Mullikin JC; Wooster R; Stratton MR Cancer and genomics	29	14
106	1	1350 2002 JOURNAL OF CELL SCIENCE 115(2):241-256 Cohen PTW Protein phosphatase 1 - targeted in many directions	29	0
107	1	1598 2002 NATURE REVIEWS CANCER 2(2):133-+ Sahai E; Marshall CJ RHO-GTPases and cancer	29	0
108	3	1785 2002 SCIENCE 295(5552):127-131 Boulton SJ; Gartner A; Reboul J; Vaglio P; Dyson N; Hill DE; Vidal M Combined functional genomic maps of the C-elegans DNA damage response	29	4
109	3	1786 2002 SCIENCE 295(5552):131-134 Fujiyama A; Watanabe H; Toyoda A; Taylor TD; Itoh T; Tsai SF; Park HS; Yaspo ML; Lehrach H; Chen Z; Fu G; Saitou N; Osoegawa K; de Jong PJ; Suto Y; Hattori M; Sakaki Y Construction and analysis of a human-chimpanzee comparative clone map	29	13
110	5	918 2002 CHEMICAL REVIEWS 102(2):439-469 Angata T; Varki A Chemical diversity in the sialic acids and related alpha-keto acids: An evolutionary perspective	28	1
111	4	1543 2002 NATURE 415(6872):702-709 Hoffman SL; Subramanian GM; Collins FH; Venter JC Plasmodium, human and Anopheles genomics and malaria	28	2
112	14	1553 2002 NATURE 418(6894):236-243 Maniatis T; Tasic B Alternative pre-mRNA splicing and proteome expansion in metazoans	28	10
113	7	1582 2002 NATURE GENETICS 31(2):200-204 McLysaght A; Hokamp K; Wolfe KH Extensive genomic duplication during early chordate evolution	28	12
114	5	1796 2002 SCIENCE 298(5600):1912-+ Manning G; Whyte DB; Martinez R; Hunter T; Sudarsanam S The protein kinase complement of the human genome	28	2
115	1	31 2001 ANNUAL REVIEW OF GENETICS 35():501-538 Ostertag EM; Kazazian HH Biology of mammalian L1 retrotransposons	27	17
116	2	487 2001 NATURE 411(6839):759-762 Downward J The ins and outs of signalling	27	4
117	2	911 2002 CELL 110(4):521-529 Schroder ARW; Shinn P; Chen HM; Berry C; Ecker JR; Bushman F HIV-1 integration in the human genome favors active genes and local hotspots	27	3
118	6	1604 2002 NATURE REVIEWS GENETICS 3(5):391-A396 Tabor HK; Risch NJ; Myers RM Candidate-gene approaches for studying complex genetic traits: practical considerations	27	5
119	2	30 2001 ANNUAL REVIEW OF GENETICS 35():303-339 Mackay TFC The genetic architecture of quantitative traits	26	0
120	4	209 2001 EMBO REPORTS 2(11):986-991 Mattick JS Non-coding RNAs: the architects of eukaryotic complexity	26	4
121	4	300 2001 GENOME RESEARCH 11(11):1842-1847 Friedman R; Hughes AL Pattern and timing of gene duplication in animal genomes	26	12
122	1	470 2001 NATURE 409(6822):822-823 Chakravarti A Single nucleotide polymorphisms ... to a future of genetic medicine	26	13
123	2	521 2001 NATURE IMMUNOLOGY 2(12):1109-1116 McIntire JJ; Umetsu SE; Akbari O; Potter M; Kuchroo VK; Barsh GS; Freeman GJ; Umetsu DT; DeKruyff RH Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family	26	1
124	2	603 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(21):12103-12108 Camargo AA; Samaia HPB; Dias-Neto E; Simao DF; Migotto IA; Briones MRS; Costa FF; Nagai MA; Verjovski-Almeida S; Zago MA; Andrade LEC; Carrer H; El-Dorry HFA; Espreafico EM; Habr-Gama A; Giannella-Neto D; Goldman GH; Gruber A; Hackel C; Kimura ET; Maciel RMB; Marie SKN; Martins EAL; Nobrega MP; Paco-Larson ML; Pardini MIMC; Pereira GG; Pesquero JB; Rodrigues V; Rogatto SR; da Silva IDCG; Sogayar MC; Sonati MDF; Tajara EH; Valentini SR; Alberto FL; Amaral MEJ; Aneas I; Arnaldi LAT; de Assis AM; Bengtson MH; Bergamo NA; Bombonato V; de Camargo MER; Canevari RA; Carraro DM; Cerutti JM; Correa MLC; Correa RFR; Costa MCR; Curcio C; Hokama POM; Ferreira AJS; Furuzawa GK; Gushiken T; Ho PL; Kimura E; Krieger JE; Leite LCC; Majumder P; Marins M; Marques ER; Melo ASA; Melo M; Mestriner CA; Miracca EC; Miranda DC; Nascimento ALTO; Nobrega FG; Ojopi EPB; Pandolfi JRC; Pessoa LG; Prevedel AC; Rahal P; Rainho CA; Reis EMR; Ribeiro ML; da Ros N; de Sa RG; Sales MM; Sant'anna SC; dos Santos ML; da Silva AM; da Silva NP; Silva WA; da Silveira RA; Sousa JF; Stecconi D; Tsukumo F; Valente V; Soares F; Moreira ES; Nunes DN; Correa RG; Zalcberg H; Carvalho AF; Reis LFL; Brentani RR; Simpson AJG; de Souza SJ The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome	26	13
125	1	611 2001 PROTEIN EXPRESSION AND PURIFICATION 22(2):159-164 Lesley SA High-throughput proteomics: Protein expression and purification in the postgenomic world	26	4
126	2	1569 2002 NATURE BIOTECHNOLOGY 20(5):508-512 Saha S; Sparks AB; Rago C; Akmaev V; Wang CJ; Vogelstein B; Kinzler KW; Velculescu VE Using the transcriptome to annotate the genome	26	11
127	1	1581 2002 NATURE GENETICS 31(2):180-183 Lercher MJ; Urrutia AO; Hurst LD Clustering of housekeeping genes provides a unified model of gene order in the human genome	26	2
128	1	161 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(3):268-273 Brown SDM; Balling R Systematic approaches to mouse mutagenesis	25	3
129	3	518 2001 NATURE GENETICS 29(4):412-417 Davuluri RV; Grosse I; Zhang MQ Computational identification of promoters and first exons in the human genome	25	8
130	1	573 2001 ONCOGENE 20(44):6348-6371 Feller SM Crk family adaptors - signalling complex formation and biological roles	25	0
131	2	1479 2002 MOLECULAR & CELLULAR PROTEOMICS 1(4):323-333 Griffin TJ; Gygi SP; Ideker T; Rist B; Eng J; Hood L; Aebersold R Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae	25	4
132	4	1797 2002 SCIENCE 298(5601):2157-2167 Dehal P; Satou Y; Campbell RK; Chapman J; Degnan B; De Tomaso A; Davidson B; Di Gregorio A; Gelpke M; Goodstein DM; Harafuji N; Hastings KEM; Ho I; Hotta K; Huang W; Kawashima T; Lemaire P; Martinez D; Meinertzhagen IA; Necula S; Nonaka M; Putnam N; Rash S; Saiga H; Satake M; Terry A; Yamada L; Wang HG; Awazu S; Azumi K; Boore J; Branno M; Chin-bow S; DeSantis R; Doyle S; Francino P; Keys DN; Haga S; Hayashi H; Hino K; Imai KS; Inaba K; Kano S; Kobayashi K; Kobayashi M; Lee BI; Makabe KW; Manohar C; Matassi G; Medina M; Mochizuki Y; Mount S; Morishita T; Miura S; Nakayama A; Nishizaka S; Nomoto H; Ohta F; Oishi K; Rigoutsos I; Sano M; Sasaki A; Sasakura Y; Shoguchi E; Shin-i T; Spagnuolo A; Stainier D; Suzuki MM; Tassy O; Takatori N; Tokuoka M; Yagi K; Yoshizaki F; Wada S; Zhang C; Hyatt PD; Larimer F; Detter C; Doggett N; Glavina T; Hawkins T; Richardson P; Lucas S; Kohara Y; Levine M; Satoh N; Rokhsar DS The draft genome of Ciona intestinalis: Insights into chordate and vertebrate origins	25	7
133	1	15 2001 AMERICAN JOURNAL OF PATHOLOGY 158(5):1639-1651 Young AN; Amin MB; Moreno CS; Lim SD; Cohen C; Petros JA; Marshall FF; Neish AS Expression profiling of renal epithelial neoplasms - A method for tumor classification and discovery of diagnostic molecular markers	24	0
134	2	183 2001 DNA RESEARCH 8(2):85-95 Nagase T; Nakayama M; Nakajima D; Kikuno R; Ohara O Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro	24	2
135	2	477 2001 NATURE 409(6822):856-859 Aach J; Bulyk ML; Church GM; Comander J; Derti A; Shendure J Computational comparison of two draft sequences of the human genome	24	15
136	2	593 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(12):6759-6764 Fischer SEJ; Wienholds E; Plasterk RHA Regulated transposition of a fish transposon in the mouse germ line	24	3
137	1	1574 2002 NATURE GENETICS 30(1):29-30 Brett D; Pospisil H; Valcarel J; Reich J; Bork P Alternative splicing and genome complexity	24	11
138	1	282 2001 GENOME RESEARCH 11(6):1018-1033 Inoue K; Dewar K; Katsanis N; Reiter LT; Lander ES; Devon KL; Wyman DW; Lupski JR; Birren B The 1.4-Mb CMT1A duplication/HNPP deletion genomic region reveals unique genome architectural features and provides insights into the recent evolution of new genes	23	9
139	2	456 2001 MOLECULAR BIOLOGY AND EVOLUTION 18(11):2032-2039 Lercher MJ; Williams EJB; Hurst LD Local similarity in evolutionary rates extends over whole chromosomes in human-rodent and mouse-rat comparisons: Implications for understanding the mechanistic basis of the male mutation bias	23	7
140	2	612 2001 PROTEIN SCIENCE 10(10):1970-1979 Liu JF; Rost B Comparing function and structure between entire proteomes	23	1
141	1	688 2001 TRENDS IN GENETICS 17(7):373-376 Shabalina SA; Ogurtsov AY; Kondrashov VA; Kondrashov AS Selective constraint in intergenic regions of human and mouse genomes	23	9
142	3	1563 2002 NATURE BIOTECHNOLOGY 20(2):135-141 Beerli RR; Barbas CF Engineering polydactyl zinc-finger transcription factors	23	1
143	2	1741 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(20):12963-12968 Pollack JR; Sorlie T; Perou CM; Rees CA; Jeffrey SS; Lonning PE; Tibshirani R; Botstein D; Borresen-Dale AL; Brown PO Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors	23	3
144	1	11 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(3):582-589 Ardlie K; Liu-Cordero SN; Eberle MA; Daly M; Barrett J; Winchester E; Lander ES; Kruglyak L Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion	22	3
145	1	99 2001 CELL 106(2):171-182 Derkatch IL; Bradley ME; Hong JY; Liebman SW Prions affect the appearance of other prions: The story of [PIN+]	22	1
146	1	141 2001 CURRENT BIOLOGY 11(19):1503-1511 Watters JW; Dewar K; Lehoczky J; Boyartchuk V; Dietrich WF Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor	22	1
147	6	277 2001 GENOME RESEARCH 11(5):653-656 Eichler EE Segmental duplications: What's missing, misassigned, and misassembled - and should we care?	22	12
148	7	357 2001 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 286(18):2296-2307 Subramanian G; Adams MD; Venter JC; Broder S Implications of the human genome for understanding human biology and medicine	22	14
149	2	402 2001 JOURNAL OF MOLECULAR BIOLOGY 307(2):683-706 Chasman D; Adams RM Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: Structure-based assessment of amino acid variation	22	4
150	1	461 2001 MOLECULAR CELL 8(6):1351-1361 Zhu J; Mayeda A; Krainer AR Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer- bound SR proteins	22	7
151	5	1177 2002 GENOME RESEARCH 12(2):272-280 Harrison PM; Hegyi H; Balasubramanian S; Luscombe NM; Bertone P; Echols N; Johnson T; Gerstein M Molecular fossils in the human genome: Identification and analysis of the pseudogenes in chromosomes 21 and 22	22	12
152	3	1642 2002 NUCLEIC ACIDS RESEARCH 30(7):1427-1464 Anantharaman V; Koonin EV; Aravind L Comparative genomics and evolution of proteins involved in RNA metabolism	22	2
153	2	4 2001 ALIMENTARY PHARMACOLOGY & THERAPEUTICS 15(6):731-748 Ahmad T; Satsangi J; Mcgovern D; Bunce M; Jewell DP Review Article: The genetics of inflammatory bowel disease	21	0
154	2	159 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(4):464-470 Caron PR; Mullican MD; Mashal RD; Wilson KP; Su MS; Murcko MA Chemogenomic approaches to drug discovery - Commentary	21	2
155	1	369 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(37):35123-35132 Langbein L; Rogers MA; Winter H; Praetzel S; Schweizer J The catalog of human hair keratins - II. Expression of the six type II members in the hair follicle and the combined catalog of human type I and II keratins	21	1
156	2	379 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(47):43604-43610 Wang LQ; Wu Q; Qiu P; Mirza A; McGuirk M; Kirschmeier P; Greene JR; Wang YL; Pickett CB; Liu SX Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches	21	2
157	2	453 2001 MOLECULAR BIOLOGY AND EVOLUTION 18(9):1611-1630 Mattick JS; Gagen MJ The evolution of controlled multitasked gene networks: The role of introns and other noncoding RNAs in the development of complex organisms	21	6
158	2	469 2001 NATURE 409(6822):820-821 Rubin GM The draft sequences - Comparing species	21	9
159	3	472 2001 NATURE 409(6822):827-828 Birney E; Bateman A; Clamp ME; Hubbard TJ Mining the draft human genome	21	12
160	4	527 2001 NATURE REVIEWS CANCER 1(2):99-108 Relling MV; Dervieux T Pharmacogenetics and cancer therapy	21	1
161	5	711 2001 TRENDS IN MOLECULAR MEDICINE 7(11):507-512 Taylor JG; Choi EH; Foster CB; Chanock SJ Using genetic variation to study human disease	21	1
162	6	1583 2002 NATURE GENETICS 31(2):205-209 Gu X; Wang YF; Gu JY Age distribution of human gene families shows significant roles of both large- and small-scale duplications in vertebrate evolution	21	11
163	4	1599 2002 NATURE REVIEWS DRUG DISCOVERY 1(9):727-730 Hopkins AL; Groom CR The druggable genome	21	6
164	5	1640 2002 NUCLEIC ACIDS RESEARCH 30(5):1083-1090 Harrison PM; Kumar A; Lang N; Snyder M; Gerstein M A question of size: the eukaryotic proteome and the problems in defining it	21	9
165	2	1849 2002 TRENDS IN PHARMACOLOGICAL SCIENCES 23(3):140-146 Lu ZL; Saldanha JW; Hulme EC Seven-transmembrane receptors: crystals clarify	21	2
166	4	2213 2003 NATURE 421(6920):231-237 Kamath RS; Fraser AG; Dong Y; Poulin G; Durbin R; Gotta M; Kanapin A; Le Bot N; Moreno S; Sohrmann M; Welchman DP; Zipperlen P; Ahringer J Systematic functional analysis of the Caenorhabditis elegans genome using RNAi	21	2
167	2	65 2001 BIOESSAYS 23(12):1131-1137 Wade PA Methyl CpG-binding transcriptional proteins and repression	20	2
168	3	166 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):673-680 Long M Evolution of novel genes	20	8
169	1	284 2001 GENOME RESEARCH 11(7):1237-1245 Hu GK; Madore SJ; Moldover B; Jatkoe T; Balaban D; Thomas J; Wang YX Predicting splice variant from DNA chip expression data	20	12
170	1	385 2001 JOURNAL OF CELL BIOLOGY 154(1):123-136 Young P; Ehler E; Gautel M Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly	20	2
171	2	428 2001 LABORATORY INVESTIGATION 81(10):1331-1338 Hoos A; Cordon-Cardo C Tissue microarray profiling of cancer specimens and cell lines: Opportunities and limitations	20	0
172	2	501 2001 NATURE BIOTECHNOLOGY 19(11):1067-1070 Wade-Martins R; Smith ER; Tyminski E; Chiocca EA; Saeki Y An infectious transfer and expression system for genomic DNA loci in human and mouse cells	20	0
173	3	1552 2002 NATURE 418(6893):79-85 Glockner G; Eichinger L; Szafranski K; Pachebat JA; Bankier AT; Dear PH; Lehmann D; Baumgart C; Parra G; Abril JF; Guigo R; Kumpf K; Tunggal B; Cox E; Quail MA; Platzer M; Rosenthal A; Noegel AA; Dictyostelium Genome Sequencing Sequence and analysis of chromosome 2 of Dictyostelium discoideum	20	2
174	3	1566 2002 NATURE BIOTECHNOLOGY 20(4):353-358 Yeakley JM; Fan JB; Doucet D; Luo L; Wickham E; Ye Z; Chee MS; Fu XD Profiling alternative splicing on fiber-optic arrays	20	6
175	5	1603 2002 NATURE REVIEWS GENETICS 3(5):370-379 Batzer MA; Deininger PL Alu repeats and human genomic diversity	20	9
176	2	1791 2002 SCIENCE 296(5569):907-910 Clark TA; Sugnet CW; Ares M Genomewide analysis of mRNA processing in yeast using splicing- specific microarrays	20	6
177	10	291 2001 GENOME RESEARCH 11(9):1541-1548 Kent WJ; Haussler D Assembly of the working draft of the human genome with GigAssembler	19	12
178	2	315 2001 GENOMICS 77(1-2):71-78 Das M; Burge CB; Park E; Colinas J; Pelletier J Assessment of the total number of human transcription units	19	8
179	2	592 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(8):4277-4278 Hazbun TR; Fields S Networking proteins in yeast	19	5
180	3	1614 2002 NEW ENGLAND JOURNAL OF MEDICINE 347(19):1512-1520 Guttmacher AE; Collins FS Genomic medicine - A primer	19	3
181	1	1712 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(2):574-579 Paegel BM; Emrich CA; Weyemayer GJ; Scherer JR; Mathies RA High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor	19	2
182	2	71 2001 BIOINFORMATICS 17(10):878-889 Frith MC; Hansen U; Weng ZP Detection of cis-element clusters in higher eukaryotic DNA	18	4
183	2	118 2001 CHROMOSOME RESEARCH 9(7):541-567 Cremer M; von Hase J; Volm T; Brero A; Kreth G; Walter J; Fischer C; Solovei I; Cremer C; Cremer T Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells	18	4
184	2	365 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(25):23161-23172 Kraev A; Quednau BD; Leach S; Li XF; Dong H; Winkfein R; Perizzolo M; Cai XJ; Yang RM; Philipson KD; Lytton J Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3	18	1
185	1	403 2001 JOURNAL OF MOLECULAR BIOLOGY 311(1):17-40 Carroll ML; Roy-Engel AM; Nguyen SV; Salem AH; Vogel E; Vincent B; Myers J; Ahmad Z; Nguyen L; Sammarco M; Watkins WS; Henke J; Makalowski W; Jorde LB; Deininger PL; Batzer MA Large-scale analysis of the Alu Ya5 and Yb8 subfamilies and their contribution to human genomic diversity	18	13
186	1	448 2001 MOLECULAR AND CELLULAR BIOLOGY 21(23):7913-7922 Lorincz MC; Schubeler D; Groudine M Methylation-mediated proviral silencing is associated with MeCP2 recruitment and localized histone H3 deacetylation	18	0
187	2	468 2001 NATURE 409(6822):818-820 Bork P; Copley R The draft sequences - Filling in the gaps	18	9
188	2	480 2001 NATURE 409(6822):942-943 Bentley DR; Deloukas P; Dunham A; French L; Gregory SG; Humphray SJ; Mungall AJ; Ross MT; Carter NP; Dunham I; Scott CE; Ashcroft KJ; Atkinson AL; Aubin K; Beare DM; Bethel G; Brady N; Brook JC; Burford DC; Burrill WD; Burrows C; Butler AP; Carder C; Catanese JJ; Clee CM; Clegg SM; Cobley V; Coffey AJ; Cole CG; Collins JE; Conquer JS; Cooper RA; Culley KM; Dawson E; Dearden FL; Durbin RM; de Jong PJ; Dhami PD; Earthrowl ME; Edwards CA; Evans RS; Gillson CJ; Ghori J; Green L; Gwilliam R; Halls KS; Hammond S; Harper GL; Heathcott RW; Holden JL; Holloway E; Hopkins BL; Howard PJ; Howell GR; Huckle EJ; Hughes J; Hunt PJ; Hunt SE; Izmajlowicz M; Jones CA; Joseph SS; Laird G; Langford CF; Lehvaslaiho MH; Leversha MA; McCann OT; McDonald LM; McDowall J; Maslen GL; Mistry D; Moschonas NK; Neocleous V; Pearson DM; Phillips KJ; Porter KM; Prathalingam SR; Ramsey YH; Ranby SA; Rice CM; Rogers J; Rogers LJ; Sarafidou T; Scott DJ; Sharp GJ; Shaw-Smith CJ; Smink LJ; Soderlund C; Sotheran EC; Steingruber HE; Sulston JE; Taylor A; Taylor RG; Thorpe AA; Tinsley E; Warry GL; Whittaker A; Whittaker P; Williams SH; Wilmer TE; Wooster R; Wright CL The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X	18	12
189	3	540 2001 NATURE REVIEWS GENETICS 2(10):801-809 Brenner SE A tour of structural genomics	18	2
190	2	626 2001 SCIENCE 291(5507):1219-+ Paabo S Genomics and society - The human genome and our view of ourselves	18	7
191	3	634 2001 SCIENCE 292(5523):1848-1850 Andersson JO; Doolittle WF; Nesbo CL Genomics - Are there bugs in our genome?	18	9
192	2	665 2001 TOXICOLOGY LETTERS 122(3):189-203 Frueh FW; Hayashibara KC; Brown PO; Whitlock JP Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression	18	0
193	1	693 2001 TRENDS IN GENETICS 17(9):528-535 Slavotinek AM; Biesecker LG Unfolding the role of chaperones and chaperonins in human disease	18	0
194	2	746 2002 AMERICAN JOURNAL OF HUMAN GENETICS 70(3):593-603 Gretarsdottir S; Sveinbjornsdottir S; Jonsson HH; Jakobsson F; Einarsdottir E; Agnarsson U; Shkolny D; Einarsson G; Gudjonsdottir HM; Valdimarsson EM; Einarsson OB; Thorgeirsson G; Hadzic R; Jonsdottir S; Reynisdottir ST; Bjarnadottir SM; Gudmundsdottir T; Gudlaugsdottir GJ; Gill R; Lindpaintner K; Sainz J; Hannesson HH; Sigurdsson GT; Frigge ML; Kong A; Gudnason V; Stefansson K; Gulcher JR Localization of a susceptibility gene for common forms of stroke to 5q12	18	3
195	2	1030 2002 DRUG DISCOVERY TODAY 7(4):235-246 Wise A; Gearing K; Rees S Target validation of G-protein coupled receptors	18	4
196	2	1567 2002 NATURE BIOTECHNOLOGY 20(4):376-380 Kawasaki H; Onuki R; Suyama E; Taira K Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries	18	3
197	4	1725 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(7):4424-4429 Tanabe H; Muller S; Neusser M; von Hase J; Calcagno E; Cremer M; Solovei I; Cremer C; Cremer T Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates	18	4
198	3	1742 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(21):13675-13680 Chumakov I; Blumenfeld M; Guerassimenko O; Cavarec L; Palicio M; Abderrahim H; Bougueleret L; Barry C; Tanaka H; La Rosa P; Puech A; Tahri N; Cohen-Akenine A; Delabrosse S; Lissarrague S; Picard FP; Maurice K; Essioux L; Millasseau P; Grel P; Debailleul V; Simon AM; Caterina D; Dufaure I; Malekzadeh K; Belova M; Luan JJ; Bouillot M; Sambucy JL; Primas G; Saumier M; Boubkiri N; Martin-Saumier S; Nasroune M; Peixoto H; Delaye A; Pinchot V; Bastucci M; Guillou S; Chevillon M; Sainz-Fuertes R; Meguenni S; Aurich-Costa J; Cherif D; Gimalac A; Van Duijn C; Gauvreau D; Quelette G; Fortier I; Realson J; Sherbatich T; Riazanskaia N; Rogaev E; Raeymaekers P; Aerssens J; Konings F; Luyten W; Macciardi F; Sham PC; Straub RE; Weinberger DR; Cohen N; Cohen D Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia	18	2
199	1	1787 2002 SCIENCE 295(5559):1482-1485 Meyerowitz EM Comparative genomics - Plants compared to animals: The broadest comparative study of development	18	1
200	6	1795 2002 SCIENCE 298(5591):149-159 Zdobnov EM; von Mering C; Letunic I; Torrents D; Suyama M; Copley RR; Christophides GK; Thomasova D; Holt RA; Subramanian GM; Mueller HM; Dimopoulos G; Law JH; Wells MA; Birney E; Charlab R; Halpern AL; Kokoza E; Kraft CL; Lai ZW; Lewis S; Louis C; Barillas-Mury C; Nusskern D; Rubin GM; Salzberg SL; Sutton GG; Topalis P; Wides R; Wincker P; Yandell M; Collins FH; Ribeiro J; Gelbart WM; Kafatos FC; Bork P Comparative genome and proteome analysis of anopheles gambiae and Drosophila melanogaster	18	3

#	Cited nodes	Nodes / Authors	GCS	LCS
201	3	103 2001 CELL 106(5):619-632 Dong XZ; Han SK; Zylka MJ; Simon MI; Anderson DJ A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons	17	2
202	2	169 2001 CURRENT OPINION IN MOLECULAR THERAPEUTICS 3(3):229-234 Kole R; Sazani P Antisense effects in the cell nucleus: Modification of splicing	17	2
203	6	332 2001 HUMAN MOLECULAR GENETICS 10(20):2215-2223 Horvath JE; Bailey JA; Locke DP; Eichler EE Lessons from the human genome: transitions between euchromatin and heterochromatin	17	9
204	1	374 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(43):39608-39617 Blobe GC; Liu XD; Fang SJJ; How T; Lodish HF A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling - Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC	17	0
205	6	637 2001 SCIENCE 292(5525):2264-2266 O'Brien SJ; Eizirik E; Murphy WJ Genomics - On choosing mammalian genomes for sequencing	17	0
206	3	671 2001 TRENDS IN BIOTECHNOLOGY 19(10):S40-S48 Simpson RJ; Dorow DS Cancer proteomics: from signaling networks to tumor markers	17	1
207	2	695 2001 TRENDS IN GENETICS 17(10):554-556 Robinson-Rechavi M; Carpentier AS; Duffraisse M; Laudet V How many nuclear hormone receptors are there in the human genome?	17	0
208	2	696 2001 TRENDS IN GENETICS 17(11):637-645 Hacia JG Genome of the apes	17	6
209	2	743 2002 AMERICAN JOURNAL OF HUMAN GENETICS 70(2):425-434 Schaid DJ; Rowland CM; Tines DE; Jacobson RM; Poland GA Score tests for association between traits and haplotypes when linkage phase is ambiguous	17	2
210	1	1174 2002 GENOME RESEARCH 12(1):177-189 Batzoglou S; Jaffe DB; Stanley K; Butler J; Gnerre S; Mauceli E; Berger B; Mesirov JP; Lander ES ARACHNE: A whole-genome shotgun assembler	17	8
211	2	1697 2002 PLANT CELL 14(3):537-545 Chen MS; Presting G; Barbazuk WB; Goicoechea JL; Blackmon B; Fang FC; Kim H; Frisch D; Yu YS; Sun SH; Higingbottom S; Phimphilai J; Phimphilai D; Thurmond S; Gaudette B; Li P; Liu JD; Hatfield J; Main D; Farrar K; Henderson C; Barnett L; Costa R; Williams B; Walser S; Atkins M; Hall C; Budiman MA; Tomkins JP; Luo MZ; Bancroft I; Salse J; Regad F; Mohapatra T; Singh NK; Tyagi AK; Soderlund C; Dean RA; Wing RA An integrated physical and genetic map of the rice genome	17	0
212	2	250 2001 GENE 277(1-2):31-47 Goldstrohm AC; Greenleaf AL; Garcia-Blanco MA Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing	16	2
213	2	293 2001 GENOME RESEARCH 11(10):1660-1676 Meyers BC; Tingley SV; Morgante M Abundance, distribution, and transcriptional activity of repetitive elements in the maize genome	16	5
214	2	297 2001 GENOME RESEARCH 11(10):1758-1765 Suzuki H; Fukunishi Y; Kagawa I; Saito R; Oda H; Endo T; Kondo S; Bono H; Okazaki Y; Hayashizaki Y Protein-protein interaction panel using mouse full-length cDNAs	16	5
215	2	304 2001 GENOME RESEARCH 11(11):1913-1925 Cutler DJ; Zwick ME; Carrasquillo MM; Yohn CT; Tobin KP; Kashuk C; Mathews DJ; Shah NA; Eichler EE; Warrington JA; Chakravarti A High-throughput variation detection and genotyping using microarrays	16	1
216	2	342 2001 IMMUNITY 15(3):337-349 Glusman G; Rowen L; Lee I; Boysen C; Roach JC; Smit AFA; Wang K; Koop BF; Hood L Comparative genomics of the human and mouse T cell receptor loci	16	3
217	2	422 2001 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 123(38):9490-9491 Zweckstetter M; Bax A Single-step determination of protein substructures using dipolar couplings: Aid to structural genomics	16	0
218	1	473 2001 NATURE 409(6822):844-846 Murray AW; Marks D Can sequencing shed light on cell cycling?	16	7
219	2	511 2001 NATURE GENETICS 29(1):88-91 Katsanis N; Worley KC; Lupski JR An evaluation of the draft human genome sequence	16	11
220	5	533 2001 NATURE REVIEWS GENETICS 2(7):493-503 Stein L Genome annotation: From sequence to biology	16	9
221	7	536 2001 NATURE REVIEWS GENETICS 2(8):573-583 Green ED Strategies for the systematic sequencing of complex genomes	16	10
222	2	550 2001 NEOPLASIA 3(4):314-323 Dai ZY; Lakshmanan RR; Zhu WG; Smiraglia DJ; Rush LJ; Fruhwald MC; Brena RM; Li B; Wright FA; Ross P; Otterson GA; Plass C Global methylation profiling of lung cancer identifies novel methylated genes	16	2
223	1	600 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(20):11193-11198 Lim LP; Burge CB A computational analysis of sequence features involved in recognition of short introns	16	4
224	2	608 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(26):15203-15208 Nacht M; Dracheva T; Gao YH; Fujii T; Chen YD; Player A; Akmaev V; Cook B; Dufault M; Zhang M; Zhang W; Guo MZ; Curran J; Han S; Sidransky D; Buetow K; Madden SL; Jen J Molecular characteristics of non-small cell lung cancer	16	4
225	2	661 2001 STRUCTURE 9(8):717-723 Wolfe SA; Grant RA; Elrod-Erickson M; Pabo CO Beyond the "recognition code": Structures of two Cys(2)His(2) zinc finger/TATA box complexes	16	4
226	1	675 2001 TRENDS IN BIOTECHNOLOGY 19(8):288-292 Dean PM; Zanders ED; Bailey DS Industrial-scale, genomics-based drug design and discovery	16	0
227	2	793 2002 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 42():209-234 Zhang ZY Protein tyrosine phosphatases: Structure and function, substrate specificity, and inhibitor development	16	0
228	5	1568 2002 NATURE BIOTECHNOLOGY 20(4):393-396 Cai WW; Mao JH; Chow CW; Damani S; Balmain A; Bradley A Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays	16	3
229	2	1585 2002 NATURE GENETICS 31(3):255-265 Wu LF; Hughes TR; Davierwala AP; Robinson MD; Stoughton R; Altschuler SJ Large-scale prediction of Saccharomyces cerevisiae gene function using overlapping transcriptional clusters	16	0
230	6	1590 2002 NATURE GENETICS 32(1):135-142 Reich DE; Schaffner SF; Daly MJ; McVean G; Mullikin JC; Higgins JM; Richter DJ; Lander ES; Altshuler D Human genome sequence variation and the influence of gene history, mutation and recombination	16	1
231	2	23 2001 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 40(18):3341-+ Wess G; Urmann M; Sickenberger B Medicinal chemistry: Challenges and opportunities	15	1
232	3	383 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(50):47733-47741 Pflum MKH; Tong JK; Lane WS; Schreiber SL Histone deacetylase I phosphorylation promotes enzymatic activity and complex formation	15	0
233	1	416 2001 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 299(1):268-276 Weiner DM; Burstein ES; Nash N; Croston GE; Currier EA; Vanover KE; Harvey SC; Donohue E; Hansen HC; Andersson CM; Spalding TA; Gibson DFC; Krebs-Thomson K; Powell SB; Geyer MA; Hacksell U; Brann MR 5-hydroxytryptamine(2A) receptor inverse agonists as antipsychotics	15	2
234	4	454 2001 MOLECULAR BIOLOGY AND EVOLUTION 18(9):1694-1702 Wuchty S Scale-free behavior in protein domain networks	15	2
235	1	460 2001 MOLECULAR CELL 8(5):937-946 Garvie CW; Wolberger C Recognition of specific DNA sequences	15	0
236	2	950 2002 CURRENT BIOLOGY 12(1):R32-R40 Smith FD; Scott JD Signaling complexes: Junctions on the intracellular information super highway	15	0
237	1	1176 2002 GENOME RESEARCH 12(2):222-231 Grisart B; Coppieters W; Farnir F; Karim L; Ford C; Berzi P; Cambisano N; Mni M; Reid S; Simon P; Spelman R; Georges M; Snell R Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition	15	1
238	2	1232 2002 GENOMICS 79(4):464-470 Wain HM; Bruford EA; Lovering RC; Lush MJ; Wright MW; Povey S Guidelines for human gene nomenclature	15	2
239	2	1473 2002 MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS 66(1):39-+ Graves PR; Haystead TAJ Molecular biologist's guide to proteomics	15	2
240	3	1721 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(6):3712-3716 Waterston RH; Lander ES; Sulston JE On the sequencing of the human genome	15	9
241	2	72 2001 BIOINFORMATICS 17(10):988-996 Rzhetsky A; Gomez SM Birth of scale-free molecular networks and the number of distinct DNA and protein domains per genome	14	3
242	1	97 2001 CELL 105(2):173-176 Sternberg PW Working in the post-genomic C-elegans world	14	3
243	1	112 2001 CHEMICAL REVIEWS 101(8):2313-2340 Jackson MD; Denu JM Molecular reactions of protein phosphatases - Insights from structure and chemistry	14	1
244	2	116 2001 CHINESE SCIENCE BULLETIN 46(23):1937-1942 Yu J; Hu SN; Wang J; Li SG; Wong KSG; Liu B; Deng Y; Dai L; Zhou Y; Zhang XQ; Cao ML; Liu J; Sun JD; Tang JB; Chen YJ; Huang XB; Lin W; Ye C; Tong W; Cong LJ; Geng JN; Han YJ; Li L; Li W; Hu GQ; Huang XG; Li WJ; Li J; Liu ZW; Li L; Liu JP; Qi QH; Liu JS; Li L; Wang XG; Lu H; Wu TT; Zhu M; Ni PX; Han H; Dong W; Ren XY; Feng XL; Cui P; Li XR; Wang H; Xu X; Zhai WX; Xu Z; Zhang JS; He SJ; Zhang JG; Xu JC; Zhang KL; Zheng XW; Dong JH; Zeng WY; Tao L; Chen XW; He J; Liu DF; Tian W; Tian CG; Xia HG; Li G; Gao H; Li P; Chen W; Wang XD; Zhang Y; Hu JF; Wang J; Liu S; Yang J; Zhang GY; Xiong YQ; Li ZJ; Mao L; Zhou CS; Zhu Z; Chen RS; Hao BL; Zheng WM; Chen SY; Guo W; Li GJ; Liu SQ; Huang GY; Tao M; Wang J; Zhu LH; Yuan LP; Yang HM A draft sequence of the rice (Oryza sativa ssp indica) genome	14	3
245	2	121 2001 CIRCULATION RESEARCH 89(6):547-554 Faber BCG; Cleutjens KBJM; Niessen RLJ; Aarts PLJW; Boon W; Greenberg AS; Kitslaar PJEHM; Tordoir JHM; Daemen MJAP Identification of genes potentially involved in rupture of human atherosclerotic plaques	14	0
246	1	142 2001 CURRENT BIOLOGY 11(19):1531-1535 Turner G; Barbulescu M; Su M; Jensen-Seaman MI; Kidd KK; Lenz J Insertional polymorphisms of full-length endogenous retroviruses in humans	14	7
247	4	152 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):622-625 Dean NM Functional genomics and target validation approaches using antisense oligonucleotide technology	14	1
248	6	244 2001 GENE 276(1-2):3-13 Bernardi G Misunderstandings about isochores. Part 1	14	12
249	2	249 2001 GENE 276(1-2):73-81 Pesole G; Mignone F; Gissi C; Grillo G; Licciulli F; Liuni S Structural and functional features of eukaryotic mRNA untranslated regions	14	4
250	2	251 2001 GENE 277(1-2):49-62 Sturm RA; Teasdale RD; Box NF Human pigmentation genes: identification, structure and consequences of polymorphic variation	14	1
251	1	309 2001 GENOME RESEARCH 11(12):2050-2058 Ovchinnikov I; Troxel AB; Swergold GD Genomic characterization of recent human LINE-1 insertions: Evidence supporting random insertion	14	13
252	1	328 2001 HUMAN MOLECULAR GENETICS 10(13):1379-1386 Sakai K; Shirasawa S; Ishikawa N; Ito K; Tamai H; Kuma K; Akamizu T; Tanimura M; Furugaki K; Yamamoto K; Sasazuki T Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q133 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese	14	2
253	1	329 2001 HUMAN MOLECULAR GENETICS 10(18):1995-2011 Sutherland HGE; Mumford GK; Newton K; Ford LV; Farrall R; Dellaire G; Caceres JF; Bickmore WA Large-scale identification of mammalian proteins localized to nuclear sub-compartments	14	3
254	2	376 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(43):40282-40287 Angata T; Varki NM; Varki A A second uniquely human mutation affecting sialic acid biology	14	7
255	1	392 2001 JOURNAL OF CELLULAR PHYSIOLOGY 188(2):161-169 Cillo C; Cantile M; Faiella A; Boncinelli E Homeobox genes in normal and malignant cells	14	2
256	1	418 2001 JOURNAL OF STRUCTURAL BIOLOGY 134(2-3):191-203 Lupas AN; Ponting CP; Russell RB On the evolution of protein folds: Are similar motifs in different protein folds the result of convergence, insertion, or relics of an ancient peptide world?	14	3
257	1	489 2001 NATURE 411(6841):1013-1014 Roelofs J; Van Haastert PJM Genomics - Genes lost during evolution	14	8
258	1	512 2001 NATURE GENETICS 29(2):201-205 Hudson TJ; Church DM; Greenaway S; Nguyen H; Cook A; Steen RG; Van Etten WJ; Castle AB; Strivens MA; Trickett P; Heuston C; Davison C; Southwell A; Hardisty R; Varela-Carver A; Haynes AR; Rodriguez-Tome P; Doi H; Ko MSH; Pontius J; Schriml L; Wagner L; Maglott D; Brown SDM; Lander ES; Schuler G; Denny P A radiation hybrid map of mouse genes	14	7
259	2	541 2001 NATURE REVIEWS GENETICS 2(11):858-868 Lindsay EA Chromosomal microdeletions: Dissecting del22q11 syndrome	14	0
260	2	546 2001 NATURE REVIEWS NEUROSCIENCE 2(12):861-870 Heintz N Bac to the future: The use of bac transgenic mice for neuroscience research	14	5
261	3	1602 2002 NATURE REVIEWS GENETICS 3(5):329-341 Feschotte C; Jiang N; Wessler SR Plant transposable elements: Where genetics meets genomics	14	4
262	2	1720 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(5):3076-3080 Wang TL; Rago C; Silliman N; Ptak J; Markowitz S; Willson JKV; Parmigiani G; Kinzler KW; Vogelstein B; Velculescu VE Prevalence of somatic alterations in the colorectal cancer cell genome	14	0
263	3	1846 2002 TRENDS IN MICROBIOLOGY 10(1):1-4 Lawrence JG; Ochman H Reconciling the many faces of lateral gene transfer	14	2
264	2	7 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(1):159-178 Rannala B; Reeve JP High-resolution multipoint linkage-disequilibrium mapping in the context of a human genome sequence	13	3
265	2	89 2001 BRITISH MEDICAL JOURNAL 323(7313):611-615 Aitman TJ Science, medicine, and the future - DNA microarrays in medical practice	13	0
266	2	101 2001 CELL 106(4):391-394 Hastie ND Life, sex, and WT1 isoforms - Three amino acids can make all the difference	13	2
267	2	113 2001 CHEMISTRY & BIOLOGY 8(10):931-939 Famulok M; Blind M; Mayer G Intramers as promising new tools in functional proteomics	13	0
268	2	119 2001 CHROMOSOME RESEARCH 9(7):569-584 Habermann FA; Cremer M; Walter J; Kreth G; von Hase J; Bauer K; Wienberg J; Cremer C; Cremer T; Solovei I Arrangements of macro- and microchromosomes in chicken cells	13	3
269	1	265 2001 GENETICS 159(1):279-290 Roy-Engel AM; Carroll ML; Vogel E; Garber RK; Nguyen SV; Salem AH; Batzer MA; Deininger PL Alu insertion polymorphisms for the study of human genomic diversity	13	0
270	2	268 2001 GENETICS 159(2):907-911 Galtier N; Piganeau G; Mouchiroud D; Duret L GC-content evolution in mammalian genomes: The biased gene conversion hypothesis	13	6
271	1	310 2001 GENOME RESEARCH 11(12):2059-2065 Ostertag EM; Kazazian HH Twin priming: A proposed mechanism for the creation of inversions in L1 retrotransposition	13	12
272	2	500 2001 NATURE BIOTECHNOLOGY 19(5):440-445 Harrington JJ; Sherf B; Rundlett S; Jackson PD; Perry R; Cain S; Leventhal C; Thornton M; Ramachandran R; Whittington J; Lerner L; Costanzo D; McElligott K; Boozer S; Mays R; Smith E; Veloso N; Klika A; Hess J; Cothren K; Lo K; Offenbacher J; Danzig J; Ducar M Creation of genome-wide protein expression libraries using random activation of gene expression	13	4
273	1	522 2001 NATURE MEDICINE 7(3):277-279 Almind K; Doria A; Kahn R Putting the genes for type II diabetes on the map	13	0
274	1	537 2001 NATURE REVIEWS GENETICS 2(8):597-606 Hurst GDD; Werren JH The role of selfish genetic elements in eukaryotic evolution	13	3
275	2	674 2001 TRENDS IN BIOTECHNOLOGY 19(7):266-272 Maggio ET; Ramnarayan K Recent developments in computational proteomics	13	3
276	2	676 2001 TRENDS IN BIOTECHNOLOGY 19(10):412-415 Noordewier MO; Warren PV Gene expression microarrays and the integration of biological knowledge	13	1
277	3	699 2001 TRENDS IN GENETICS 17(12):685-687 Peri S; Pandey A A reassessment of the translation initiation codon in vertebrates	13	0
278	2	733 2002 ADVANCES IN CANCER RESEARCH, VOL 84 84():57-80 Jaffe AB; Hall A Rho GTPases in transformation and metastasis	13	0
279	6	909 2002 CELL 110(3):315-325 Gilbert N; Lutz-Prigge S; Moran JV Genomic deletions created upon LINE-1 retrotransposition	13	12
280	6	910 2002 CELL 110(3):327-338 Symer DE; Connelly C; Szak ST; Caputo EM; Cost GJ; Parmigiani G; Boeke JD Human L1 retrotransposition is associated with genetic instability in vivo	13	12
281	4	1168 2002 GENOME RESEARCH 12(1):3-15 DeSilva U; Elnitski L; Idol JR; Doyle JL; Gan WN; Thomas JW; Schwartz S; Dietrich NL; Beckstrom-Sternberg SM; McDowell JC; Blakesley RW; Bouffard GG; Thomas PJ; Touchman JW; Miller W; Green ED Generation and comparative analysis of similar to 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome	13	6
282	1	1548 2002 NATURE 417(6887):447-452 Enomoto A; Kimura H; Chairoungdua A; Shigeta Y; Jutabha P; Cha SH; Hosoyamada M; Takeda M; Sekine T; Igarashi T; Matsuo H; Kikuchi Y; Oda T; Ichida K; Hosoya T; Shimokata K; Niwa T; Kanai Y; Endou H Molecular identification of a renal urate-anion exchanger that regulates blood urate levels	13	2
283	2	1736 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10335-10340 Jessani N; Liu YS; Humphrey M; Cravatt BF Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness	13	3
284	2	16 2001 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 281(5):C1587-C1595 Zhao BT; Bowden RA; Stavchansky SA; Bowman PD Human endothelial cell response to gram-negative lipopolysaccharide assessed with cDNA microarrays	12	1
285	2	57 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 288(4):933-939 Yabuuchi H; Shimizu H; Takayanagi S; Ishikawa T Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12	12	0
286	1	60 2001 BIOCHEMICAL SOCIETY TRANSACTIONS 29():377-384 Lemmon MA; Ferguson KM Molecular determinants in pleckstrin homology domains that allow specific recognition of phosphoinositides	12	0
287	2	108 2001 CELLULAR AND MOLECULAR LIFE SCIENCES 58(7):868-884 Jonsson AP Mass spectrometry for protein and peptide characterisation	12	1
288	2	148 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(4):348-354 Heinemann U; Illing G; Oschkinat H High-throughput three-dimensional protein structure determination	12	0
289	1	269 2001 GENETICS 159(3):1151-1162 Ciobanu D; Bastiaansen J; Malek M; Helm J; Woollard J; Plastow G; Rothschild M Evidence for new alleles in the protein kinase adenosine monophosphate-activated gamma(3)-subunit gene associated with low glycogen content in pig skeletal muscle and improved meat quality	12	0
290	1	273 2001 GENOME RESEARCH 11(4):540-546 Gentles AJ; Karlin S Genome-scale compositional comparisons in eukaryotes	12	2
291	1	305 2001 GENOME RESEARCH 11(11):1935-1943 Kwitek AE; Tonellato PJ; Chen D; Gullings-Handley J; Cheng YJS; Twigger S; Scheetz TE; Casavant TL; Stoll M; Nobrega MA; Shiozawa M; Soares MB; Sheffield VC; Jacob HJ Automated construction of high-density comparative maps between rat, human, and mouse	12	3
292	2	333 2001 HUMAN MOLECULAR GENETICS 10(21):2319-2328 Miller MP; Kumar S Understanding human disease mutations through the use of interspecific genetic variation	12	2
293	1	382 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(50):46685-46688 Hernandez H; Robinson CV Dynamic protein complexes: Insights from mass spectrometry	12	1
294	1	393 2001 JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 21(7):755-778 Read SJ; Parsons AA; Harrison DC; Philpott K; Kabnick K; O'Brien S; Clark S; Brawner M; Bates S; Gloger I; Legos JJ; Barone FC Stroke genomics: Approaches to identify, validate, and understand ischemic stroke gene expression	12	0
295	2	471 2001 NATURE 409(6822):824-826 Wolfsberg TG; McEntyre J; Schuler GD Guide to the draft human genome	12	7
296	1	589 2001 PLANT CELL 13(6):1263-1279 Prigge MJ; Wagner DR The Arabidopsis SERRATE gene encodes a zinc-finger protein required for normal shoot development	12	0
297	3	604 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(22):12444-12449 Sun H; Yabuki A; Maizels N A human nuclease specific for G4 DNA	12	0
298	2	706 2001 TRENDS IN MICROBIOLOGY 9(12):611-617 McDevitt D; Rosenberg M Exploiting genomics to discover new antibiotics	12	0
299	3	795 2002 ANNUAL REVIEW OF PSYCHOLOGY 53():435-462 Crabbe JC Genetic contributions to addiction	12	0
300	1	817 2002 BIOCHEMICAL JOURNAL 362():513-532 Van Schaftingen E; Gerin I The glucose-6-phosphatase system	12	0

#	Cited nodes	Nodes / Authors	GCS	LCS
301	2	841 2002 BIOINFORMATICS 18(3):440-445 Ma B; Tromp J; Li M PatternHunter: faster and more sensitive homology search	12	6
302	2	1322 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(5):3537-3543 Frankel A; Yadav N; Lee JH; Branscombe TL; Clarke S; Bedford MT The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity	12	0
303	1	1390 2002 JOURNAL OF MEDICINAL CHEMISTRY 45(6):1151-1175 McCluskey A; Sim ATR; Sakoff JA Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies	12	2
304	2	1396 2002 JOURNAL OF MOLECULAR BIOLOGY 315(5):1063-1073 Liu B; Huang L; Sihlbom C; Burlingame A; Marks JD Towards proteome-wide production of monoclonal antibody by phage display	12	2
305	2	1625 2002 NUCLEIC ACIDS RESEARCH 30(1):1-12 Baxevanis AD The Molecular Biology Database Collection: 2002 update	12	3
306	2	1637 2002 NUCLEIC ACIDS RESEARCH 30(1):328-331 Suzuki Y; Yamashita R; Nakai K; Sugano S DBTSS: DataBase of human transcriptional start sites and full- length cDNAs	12	6
307	2	9 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(3):516-527 Jenne DE; Tinschert S; Reimann H; Lasinger W; Thiel G; Hameister H; Kehrer-Sawatzki H Molecular characterization and gene content of breakpoint boundaries in patients with neurofibromatosis type 1 with 17q11.2 microdeletions	11	4
308	4	167 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):681-684 Sankoff D Gene and genome duplication	11	3
309	1	195 2001 DRUG DISCOVERY TODAY 6(13):681-688 Southan C A genomic perspective on human proteases as drug targets	11	2
310	2	247 2001 GENE 276(1-2):47-56 Oliver JL; Bernaola-Galvan P; Carpena P; Roman-Roldan R Isochore chromosome maps of eukaryotic genomes	11	9
311	2	275 2001 GENOME RESEARCH 11(5):641-643 Collins FS Contemplating the end of the beginning	11	1
312	2	278 2001 GENOME RESEARCH 11(5):667-670 Makalowski W Are we polyploids? A brief history of one hypothesis	11	5
313	3	335 2001 HUMAN MOLECULAR GENETICS 10(24):2833-2839 Eisenbarth I; Striebel AM; Moschgath E; Vogel W; Assum G Long-range sequence composition mirrors linkage disequilibrium pattern in a 1.13 Mb region of human chromosome 22	11	5
314	1	343 2001 IMMUNOGENETICS 53(5):382-394 Wang N; Morra M; Wu CB; Gullo C; Howie D; Coyle T; Engel P; Terhorst C CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells	11	0
315	4	381 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(48):45128-45136 Angata T; Hingorani R; Varki NM; Varki A Cloning and characterization of a novel mouse Siglec, mSiglec-F - Differential evolution of the mouse and human (CD33) Siglec- 3-related gene clusters	11	3
316	2	401 2001 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 33(10):1879-1886 Dempsey AA; Dzau VJ; Liew CC Cardiovascular genomics: Estimating the total number of genes expressed in the human cardiovascular system	11	3
317	2	444 2001 MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 33(6):855-867 Rankinen T; Perusse L; Rauramaa R; Rivera MA; Wolfarth B; Bouchard C The human gene map for performance and health-related fitness phenotypes	11	0
318	1	524 2001 NATURE MEDICINE 7(3):281-283 Liggett SB Pharmacogenetic applications of the Human Genome Project	11	1
319	2	628 2001 SCIENCE 291(5507):1257-+ Galas DJ Sequence interpretation - Making sense of the sequence	11	7
320	4	1284 2002 HUMAN MUTATION 20(1):57-64 Werner M; Sych M; Herbon N; Illig T; Konig IR; Wjst M Large-scale determination of SNP allele frequencies in DNA pools using MALDI-TOF mass spectrometry	11	2
321	3	1302 2002 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 10(6):677-682 Katoh M Paradigm shift in gene-finding method: From bench-top approach to desk-top approach (review)	11	0
322	2	1326 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(8):5882-5890 Finta C; Zaphiropoulos PG Intergenic mRNA molecules resulting from trans-splicing	11	3
323	2	1499 2002 MOLECULAR BIOLOGY AND EVOLUTION 19(6):926-937 Bartolome C; Maside X; Charlesworth B On the abundance and distribution of transposable elements in the genome of Drosophila melanogaster	11	2
324	2	1606 2002 NATURE REVIEWS MOLECULAR CELL BIOLOGY 3(7):498-508 Chapman ER Synaptotagmin: A Ca2+ sensor that triggers exocytosis?	11	0
325	1	1627 2002 NUCLEIC ACIDS RESEARCH 30(1):27-30 Tateno Y; Imanishi T; Miyazaki S; Fukami-Kobayashi K; Saitou N; Sugawara H; Gojobori T DNA Data Bank of Japan (DDBJ) for genome scale research in life science	11	2
326	1	1715 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(3):1665-1670 Bai JH; Wang P; Chapman ER C2A activates a cryptic Ca2+-triggered membrane penetration activity within the C2B domain of synaptotagmin I	11	3
327	3	181 2001 DISEASE MARKERS 17(2):89-98 Chanock S Candidate genes and single nucleotide polymorphisms (SNPs) in the study of human disease	10	2
328	1	206 2001 EMBO JOURNAL 20(19):5354-5360 Betts MJ; Guigo R; Agarwal P; Russell RB Exon structure conservation despite low sequence similarity: a relic of dramatic events in evolution?	10	4
329	2	230 2001 FEBS LETTERS 498(2-3):214-218 Southan C A genomic perspective on human proteases	10	1
330	1	232 2001 FEBS LETTERS 504(3):112-117 Nollert P; Harries WEC; Fu DX; Miercke LJW; Stroud RM Atomic structure of a glycerol channel and implications for substrate permeation in aqua(glycero)porins	10	0
331	2	248 2001 GENE 276(1-2):57-72 Li WT Delineating relative homogeneous G+C domains in DNA sequences	10	7
332	5	295 2001 GENOME RESEARCH 11(10):1736-1745 Zhao SY; Shatsman S; Ayodeji B; Geer K; Tsegaye G; Krol M; Gebregeorgis E; Shvartsbeyn A; Russell D; Overton L; Jiang LX; Dimitrov G; Tran K; Shetty J; Malek JA; Feldblyum T; Nierman WC; Fraser CM Mouse BAC ends quality assessment and sequence analyses	10	2
333	1	302 2001 GENOME RESEARCH 11(11):1854-1860 Ponger L; Duret L; Mouchiroud D Determinants of CpG islands: Expression in early embryo and isochore structure	10	2
334	2	426 2001 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 12(11):2348-2357 Dahan K; Fuchshuber A; Adamis S; Smaers M; Kroiss S; Loute G; Cosyns JP; Hildebrandt F; Verellen-Dumoulin C; Pirson Y Familial juvenile hyperuricemic nephropathy and autosomal dominant medullary cystic kidney disease type 2: Two facets of the same disease?	10	0
335	2	491 2001 NATURE 412(6847):580-582 Chicurel M Faster, better, cheaper genotyping	10	3
336	1	516 2001 NATURE GENETICS 29(4):375-376 Waters VL Conjugation between bacterial and mammalian cells	10	1
337	2	532 2001 NATURE REVIEWS GENETICS 2(5):392-396 Roche PA; Annas GJ Opinion - Protecting genetic privacy	10	1
338	2	563 2001 NUCLEIC ACIDS RESEARCH 29(18):3864-3872 Shchepinov MS; Denissenko MF; Smylie KJ; Worl RJ; Leppin AL; Cantor CR; Rodi CP Matrix-induced fragmentation of P3 '-N5 ' phosphoramidate- containing DNA: high-throughput MALDI-TOF analysis of genomic sequence polymorphisms	10	2
339	2	638 2001 SCIENCE 292(5526):2439-2440 Weston CR; Davis RJ Signal transduction - Signaling specificity - a complex affair	10	0
340	1	657 2001 SEMINARS IN HEMATOLOGY 38(4):382-392 Tisdale J; Sadelain M Toward gene therapy for disorders of globin synthesis	10	0
341	2	692 2001 TRENDS IN GENETICS 17(9):511-519 Bilder D PDZ proteins and polarity: functions from the fly	10	0
342	2	757 2002 AMERICAN JOURNAL OF PATHOLOGY 160(3):801-813 Scheidl SJ; Nilsson S; Kalen M; Hellstrom M; Takemoto M; Hakansson J; Lindahl P mRNA expression profiling of laser microbeam microdissected cells from slender embryonic structures	10	1
343	2	894 2002 CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 11(3):291-297 Virmani AK; Tsou JA; Siegmund KD; Shen LYC; Long TI; Laird PW; Gazdar AF; Laird-Offringa IA Hierarchical clustering of lung cancer cell lines using DNA methylation markers	10	0
344	1	899 2002 CANCER RESEARCH 62(4):1134-1138 Platzer P; Upender MB; Wilson K; Willis J; Lutterbaugh J; Nosrati A; Willson JKV; Mack D; Ried T; Markowitz S Silence of chromosomal amplifications in colon cancer	10	1
345	2	905 2002 CELL 108(3):331-344 Yoo JY; Huso DL; Nathans D; Desiderio S Specific ablation of Stat3 beta distorts the pattern of Stat3- responsive gene expression and impairs recovery from endotoxic shock	10	0
346	9	967 2002 CURRENT OPINION IN CHEMICAL BIOLOGY 6(3):375-383 Roberts GC; Smith CWJ Alternative splicing: combinatorial output from the genome	10	4
347	2	1098 2002 FRONTIERS IN BIOSCIENCE 7():C13-C32 Stoll D; Templin MF; Schrenk M; Traub PC; Vohringer CF; Joos TO Protein microarray technology	10	0
348	2	1183 2002 GENOME RESEARCH 12(3):493-502 Lee Y; Sultana R; Pertea G; Cho J; Karamycheva S; Tsai J; Parvizi B; Cheung F; Antonescu V; White J; Holt I; Liang F; Quackenbush J Cross-referencing eukaryotic genomes: TIGR orthologous gene alignments (TOGA)	10	1
349	7	1187 2002 GENOME RESEARCH 12(5):729-738 Park SS; Stankiewicz P; Bi WM; Shaw C; Lehoczky J; Dewar K; Birren B; Lupski JR Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs	10	3
350	3	1269 2002 HUMAN MOLECULAR GENETICS 11(4):419-429 Tiret L; Poirier O; Nicaud V; Barbaux S; Herrmann SM; Perret C; Raoux S; Francomme C; Lebard G; Tregouet D; Cambien F Heterogeneity of linkage disequilibrium in human genes has implications for association studies of common diseases	10	0
351	1	1391 2002 JOURNAL OF MEDICINAL CHEMISTRY 45(19):4057-4093 Jacobson KA; Jarvis MF; Williams M Purine and pyrimidine (P2) receptors as drug targets	10	0
352	3	1577 2002 NATURE GENETICS 30(2):194-200 Morgante M; Hanafey M; Powell W Microsatellites are preferentially associated with nonrepetitive DNA in plant genomes	10	0
353	2	1631 2002 NUCLEIC ACIDS RESEARCH 30(1):166-168 Kikuno R; Nagase T; Waki M; Ohara O HUGE: a database for human large proteins identified in the Kazusa cDNA sequencing project	10	3
354	2	1643 2002 NUCLEIC ACIDS RESEARCH 30(7):1575-1584 Enright AJ; Van Dongen S; Ouzounis CA An efficient algorithm for large-scale detection of protein families	10	2
355	1	1669 2002 PHARMACOGENETICS 12(3):209-220 Rosskopf D; Manthey I; Siffert W Identification and ethnic distribution of major haplotypes in the gene GNB3 encoding the G-protein beta 3 subunit	10	0
356	2	1710 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(1):309-314 Ding YC; Chi HC; Grady DL; Morishima A; Kidd JR; Kidd KK; Flodman P; Spence MA; Schuck S; Swanson JM; Zhang YP; Moyzis RK Evidence of positive selection acting at the human dopamine receptor D4 gene locus	10	2
357	5	1717 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(4):2228-2233 Maniatis N; Collins A; Xu CF; McCarthy LC; Hewett DR; Tapper W; Ennis S; Ke X; Morton NE The first linkage disequilibrium (LD) maps: Delineation of hot and cold blocks by diplotype analysis	10	0
358	1	1738 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(17):11311-11316 Mashimo T; Lucas M; Simon-Chazottes D; Frenkiel MP; Montagutelli X; Ceccaldi PE; Deubel V; Guenet JL; Depres P A nonsense mutation in the gene encoding 2 '-5 '-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice	10	0
359	2	2262 2003 NEW ENGLAND JOURNAL OF MEDICINE 348(6):529-537 Weinshilboum R Genomic medicine - Inheritance and drug response.	10	0
360	2	26 2001 ANNALS OF MEDICINE 33(4):272-285 Detera-Wadleigh SD Lithium-related genetics of bipolar disorder	9	0
361	3	35 2001 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 2():493-510 Mombaerts P The human repertoire of odorant receptor genes and pseudogenes	9	2
362	1	95 2001 CANCER RESEARCH 61(19):7118-7121 Poignee M; Backsch C; Beer K; Jansen L; Wagenbach N; Stanbridge EJ; Kirchmayr R; Schneider A; Durst M Evidence for a putative senescence gene locus within the chromosomal region 10p14-p15	9	0
363	1	104 2001 CELL 107(1):13-16 Hamilton BA; Frankel WN Of mice and genome sequence	9	2
364	2	127 2001 CLINICAL INFECTIOUS DISEASES 32(5):675-685 Fauci AS Infectious diseases: Considerations for the 21st century	9	0
365	1	172 2001 CURRENT OPINION IN OBSTETRICS & GYNECOLOGY 13(3):309-314 Zondervan KT; Cardon LR; Kennedy SH The genetic basis of endometriosis	9	0
366	1	246 2001 GENE 276(1-2):39-45 Pavlicek A; Jabbari K; Paces J; Paces V; Hejnar J; Bernardi G Similar integration but different stability of Alus and LINEs in the human genome	9	9
367	1	267 2001 GENETICS 159(2):581-588 Noor MAF; Cunningham AL; Larkin JC Consequences of recombination rate variation on quantitative trait locus mapping studies: Simulations based on the Drosophila melanogaster genome	9	1
368	1	270 2001 GENETICS 159(3):1191-1199 Urrutia AO; Hurst LD Codon usage bias covaries with expression breadth and the rate of synonymous evolution in humans, but this is not evidence for selection	9	2
369	2	430 2001 LANCET ONCOLOGY 2(11):674-682 Bertucci F; Houlgatte R; Nguyen C; Viens P; Jordan BR; Birnbaum D Gene expression profiling of cancer by use of DNA arrays: how far from the clinic?	9	0
370	3	520 2001 NATURE GENETICS 29(4):487-489 Hughes JF; Coffin JM Evidence for genomic rearrangements mediated by human endogenous retroviruses during primate evolution	9	5
371	2	554 2001 NEW ENGLAND JOURNAL OF MEDICINE 344(8):601-602 Golub TR Genome-wide views of cancer.	9	1
372	1	562 2001 NUCLEIC ACIDS RESEARCH 29(15):3258-3269 Banerjee-Basu S; Baxevanis AD Molecular evolution of the homeodomain family of transcription factors	9	0
373	2	580 2001 PHARMACOGENETICS 11(9):747-756 Freimuth RR; Eckloff B; Wieben ED; Weinshilboum RM Human sulfotransferase SULT1C1 pharmacogenetics: gene resequencing and functional genomic studies	9	0
374	1	601 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(20):11399-11404 Hayakawa T; Satta Y; Gagneux P; Varki A; Takahata N Alu-mediated inactivation of the human CMP-N-acetylneuraminic acid hydroxylase gene	9	7
375	1	610 2001 PROTEIN ENGINEERING 14(11):875-880 Visegrady B; Than NG; Kilar F; Sumegi B; Than GN; Bohn H Homology modelling and molecular dynamics studies of human placental tissue protein 13 (galectin-13)	9	0
376	2	673 2001 TRENDS IN BIOTECHNOLOGY 19(10):S67-S71 Jhoti H High-throughput structural proteomics using x-rays	9	2
377	2	710 2001 TRENDS IN MOLECULAR MEDICINE 7(11):494-502 Yaspo ML Taking a functional genomics approach in molecular medicine	9	0
378	2	713 2001 TRENDS IN MOLECULAR MEDICINE 7(11):521-526 Blackwell JM Genetics and genomics in infectious disease susceptibility	9	2
379	1	721 2001 TRENDS IN PLANT SCIENCE 6(12):566-572 Giglione C; Meinnel T Organellar peptide deformylases: universality of the N-terminal methionine cleavage mechanism	9	0
380	3	775 2002 ANALYTICAL CHEMISTRY 74(12):2833-2850 Hu S; Dovichi NJ Capillary electrophoresis for the analysis of biopolymers	9	0
381	2	794 2002 ANNUAL REVIEW OF PHYSIOLOGY 64():709-748 Schutte BC; McCray PB beta-defensins in lung host defense	9	0
382	2	812 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 293(2):722-726 Fischer H; Koenig U; Eckhart L; Tschachler E Human caspase 12 has acquired deleterious mutations	9	1
383	4	956 2002 CURRENT OPINION IN BIOTECHNOLOGY 13(1):68-71 Goodman N Biological data becomes computer literate: new advances in bioinformatics	9	2
384	5	1082 2002 EXPERT OPINION ON THERAPEUTIC PATENTS 12(6):871-905 Blaskovich MA; Kim HO Recent discovery and development of protein tyrosine phosphatase inhibitors	9	0
385	4	1083 2002 FEBS LETTERS 511(1-3):165-169 Pavlicek A; Paces J; Clay O; Bernardi G A compact view of isochores in the draft human genome sequence	9	6
386	2	1175 2002 GENOME RESEARCH 12(1):198-202 Nekrutenko A; Makova KD; Li WH The K-A/K-S ratio test for assessing the protein-coding potential of genomic regions: An empirical and simulation study	9	2
387	4	1193 2002 GENOME RESEARCH 12(7):1048-1059 Lespinet O; Wolf YI; Koonin EV; Aravind L The role of lineage-specific gene family expansion in the evolution of eukaryotes	9	4
388	5	1205 2002 GENOME RESEARCH 12(9):1350-1356 Smith NGC; Webster MT; Ellegren H Deterministic mutation rate variation in the human genome	9	4
389	1	1274 2002 HUMAN MOLECULAR GENETICS 11(13):1527-1538 Cavaille J; Seitz H; Paulsen M; Ferguson-Smith AC; Bachellerie JP Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region	9	1
390	3	1403 2002 JOURNAL OF MOLECULAR BIOLOGY 319(5):1257-1265 Jensen LJ; Gupta R; Blom N; Devos D; Tamames J; Kesmir C; Nielsen H; Staerfeldt HH; Rapacki K; Workman C; Andersen CAF; Knudsen S; Krogh A; Valencia A; Brunak S Prediction of human protein function from post-translational modifications and localization features	9	0
391	4	1502 2002 MOLECULAR BIOLOGY AND EVOLUTION 19(7):1181-1197 Birdsell JA Integrating genomics, bioinformatics, and classical genetics to study the effects of recombination on genome evolution	9	2
392	2	1586 2002 NATURE GENETICS 31(3):295-300 Ruivenkamp CAL; van Wezel T; Zanon C; Stassen APM; Vlcek C; Csikos T; Klous AM; Tripodis N; Perrakis A; Boerrigter L; Groot PC; Lindeman J; Mooi WJ; Meijjer GA; Scholten G; Dauwerse H; Paces V; van Zandwijk N; van Ommen GJB; Demant P Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers	9	0
393	2	1687 2002 PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES 357(1420):531-544 Furlong RF; Holland PWH Were vertebrates octoploid?	9	2
394	2	1752 2002 PROTEIN SCIENCE 11(3):636-641 Kallberg Y; Oppermann U; Jornvall H; Persson B Short-chain dehydrogenase/reductase (SDR) relationships: A large family with eight clusters common to human, animal, and plant genomes	9	1
395	4	2270 2003 NUCLEIC ACIDS RESEARCH 31(1):315-318 Mulder NJ; Apweiler R; Attwood TK; Bairoch A; Barrell D; Bateman A; Binns D; Biswas M; Bradley P; Bork P; Bucher P; Copley RR; Courcelle E; Das U; Durbin R; Falquet L; Fleischmann W; Griffiths-Jones S; Haft D; Harte N; Hulo N; Kahn D; Kanapin A; Krestyaninova M; Lopez R; Letunic I; Lonsdale D; Silventoinen V; Orchard SE; Pagni M; Peyruc D; Ponting CP; Selengut JD; Servant F; Sigrist CJA; Vaughan R; Zdobnov EM The InterPro Database, 2003 brings increased coverage and new features	9	0
396	3	14 2001 AMERICAN JOURNAL OF MEDICAL GENETICS 106(3):223-232 Greendale K; Pyeritz RE Empowering primary care health professionals in medical genetics: How soon? How fast? How far?	8	0
397	2	88 2001 BRITISH MEDICAL JOURNAL 322(7293):1031-1034 Mathew C Science medicine and the future - Postgenomic technologies: hunting the genes for common disorders	8	2
398	3	151 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):607-612 Griffin TJ; Goodlett DR; Aebersold R Advances in proteome analysis by mass spectrometry	8	1
399	2	156 2001 CURRENT OPINION IN CELL BIOLOGY 13(5):611-618 Brummendorf T; Lemmon V Immunoglobulin superfamily receptors: cis-interactions, intracellular adapters and alternative splicing regulate adhesion	8	1
400	2	160 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(3):247-257 Sreekumar KR; Aravind L; Koonin EV Computational analysis of human disease-associated genes and their protein products	8	5

#	Cited nodes	Nodes / Authors	GCS	LCS
401	2	217 2001 EUROPEAN JOURNAL OF NEUROSCIENCE 14(5):769-776 Huber A Scaffolding proteins organize multimolecular protein complexes for sensory signal transduction	8	0
402	1	261 2001 GENETICAL RESEARCH 78(2):121-136 Maside X; Bartolome C; Assimacopoulos S; Charlesworth B Rates of movement and distribution of transposable elements in Drosophila melanogaster: in situ hybridization vs Southern blotting data	8	1
403	2	266 2001 GENETICS 159(2):441-452 Wloch DM; Szafraniec K; Borts RH; Korona R Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae	8	0
404	2	285 2001 GENOME RESEARCH 11(7):1290-1295 Tapper WJ; Morton NE; Dunham I; Ke XY; Collins A A sequence-based integrated map of chromosome 22	8	3
405	2	318 2001 GENOMICS 78(1-2):46-54 Reymond A; Friedli M; Henrichsen CN; Chapot F; Deutsch S; Ucla C; Rossier C; Lyle R; Guipponi M; Antonarakis SE From PREDs and open reading frames to cDNA isolation: Revisiting the human chromosome 21 transcription map	8	5
406	4	358 2001 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 286(18):2322-2324 Collins FS; Guttmacher AE Genetics moves into the medical mainstream	8	2
407	2	366 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(27):25503-25511 Zhou TY; Chiang CM The intronless and TATA-less human TAF(II)55 gene contains a functional initiator and a downstream promoter element	8	1
408	2	406 2001 JOURNAL OF MOLECULAR ENDOCRINOLOGY 27(2):123-131 Akker SA; Smith PJ; Chew SL Nuclear post-transcriptional control of gene expression	8	2
409	2	419 2001 JOURNAL OF STRUCTURAL BIOLOGY 136(2):144-157 Rosenbusch JP Stability of membrane proteins: Relevance for the selection of appropriate methods for high-resolution structure determinations	8	0
410	3	436 2001 MAMMALIAN GENOME 12(8):575-581 Moldin SO; Farmer ME; Chin HR; Battey JF Trans-NIH neuroscience initiatives on mouse phenotyping and mutagenesis	8	2
411	1	497 2001 NATURE BIOTECHNOLOGY 19(3):196-196 Sorek R; Amitai M Piecing together the significance of splicing	8	5
412	2	596 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(17):9748-9753 Pevzner PA; Tang HX; Waterman MS An Eulerian path approach to DNA fragment assembly	8	2
413	2	607 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(25):14503-14508 Chiaromonte F; Yang S; Elnitski L; Yap VB; Miller W; Hardison RC Association between divergence and interspersed repeats in mammalian noncoding genomic DNA	8	5
414	2	643 2001 SCIENCE 294(5540):86-87 Avise JC Evolving genomic metaphors: A new look at the language of DNA	8	5
415	4	677 2001 TRENDS IN BIOTECHNOLOGY 19(12):496-499 Reiss T Drug discovery of the future: the implications of the human genome project	8	1
416	1	737 2002 AMERICAN JOURNAL OF EPIDEMIOLOGY 156(3):204-210 Ioannidis JPA; Rosenberg PS; Goedert JJ; O'Brien TR; Int Meta-Anal HIV Host Genetics Commentary: Meta-analysis of individual participants' data in genetic epidemiology	8	0
417	2	751 2002 AMERICAN JOURNAL OF HUMAN GENETICS 70(6):1459-1468 Stone S; Abkevich V; Hunt SC; Gutin A; Russell DL; Neff CD; Riley R; Frech GC; Hensel CH; Jammulapati S; Potter J; Sexton D; Tran T; Gibbs D; Iliev D; Gress R; Bloomquist B; Amatruda J; Rae PMM; Adams TD; Skolnick MH; Shattuck D A major predisposition locus for severe obesity, at 4p15-p14	8	0
418	2	792 2002 ANNUAL REVIEW OF NEUROSCIENCE 25():1-50 Cowan WM; Kopnisky KL; Hyman SE The human genome project and its impact on psychiatry	8	3
419	2	818 2002 BIOCHEMICAL JOURNAL 366():1-13 Tucker WC; Chapman ER Role of synaptotagmin in Ca2+-triggered exocytosis	8	0
420	3	906 2002 CELL 109(3):283-284 Daly MJ Estimating the human gene count	8	6
421	21	975 2002 CURRENT OPINION IN GENETICS & DEVELOPMENT 12(3):312-319 Stankiewicz P; Lupski JR Molecular-evolutionary mechanisms for genomic disorders	8	1
422	1	992 2002 CURRENT OPINION IN STRUCTURAL BIOLOGY 12(3):392-399 Aravind L; Mazumder R; Vasudevan S; Koonin EV Trends in protein evolution inferred from sequence and structure analysis	8	1
423	1	1012 2002 DEVELOPMENT 129(13):3021-3032 Erwin DH; Davidson EH The last common bilaterian ancestor	8	0
424	3	1032 2002 DRUG DISCOVERY TODAY 7(5):315-323 Augen J The evolving role of information technology in the drug discovery process	8	1
425	2	1044 2002 ELECTROPHORESIS 23(4):640-646 Werhahn W; Braun HP Biochemical dissection of the mitochondrial proteome from Arabidopsis thaliana by three-dimensional gel electrophoresis	8	1
426	2	1064 2002 EUKARYOTIC CELL 1(2):181-190 Nixon JEJ; Wang A; Field J; Morrison HG; McArthur AG; Sogin ML; Loftus BJ; Samuelson J Evidence for lateral transfer of genes encoding ferredoxins, nitroreductases, NADH oxidase, and alcohol dehydrogenase 3 from anaerobic prokaryotes to Giardia lamblia and Entamoeba histolytica	8	1
427	2	1107 2002 GENE 286(2):259-270 Yousef GM; Ordon MH; Foussias G; Diamandis EP Genomic organization of the siglec gene locus on chromosome 19q13.4 and cloning of two new siglec pseudogenes	8	1
428	2	1141 2002 GENES CHROMOSOMES & CANCER 34(1):104-114 Clark J; Edwards S; John M; Flohr P; Gordon T; Maillard K; Giddings I; Brown C; Bagherzadeh A; Campbell C; Shipley J; Wooster R; Cooper CS Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones	8	1
429	4	1172 2002 GENOME RESEARCH 12(1):67-80 Crosier M; Viggiano L; Guy J; Misceo D; Stones R; Wei WB; Hearn T; Ventura M; Archidiacono N; Rocchi M; Jackson MS Human paralogs of KIAA0187 were created through independent pericentromeric-directed and chromosome-specific duplication mechanisms	8	5
430	5	1186 2002 GENOME RESEARCH 12(5):713-728 Bi WM; Yan J; Stankiewicz P; Park SS; Walz K; Boerkoel CF; Potocki L; Shaffer LG; Devriendt K; Nowaczyk MJM; Inoue K; Lupski JR Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse	8	2
431	3	1233 2002 GENOMICS 79(4):587-597 Rowen L; Young J; Birditt B; Kaur A; Madan A; Philipps DL; Qin SZ; Minx P; Wilson RK; Hood L; Graveley BR Analysis of the human neurexin genes: Alternative splicing and the generation of protein diversity	8	4
432	2	1270 2002 HUMAN MOLECULAR GENETICS 11(4):451-464 Clark F; Thanaraj TA Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human	8	4
433	2	1321 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(3):2247-2257 Ward SDC; Hamdan FF; Bloodworth LM; Wess J Conformational changes that occur during M-3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy	8	1
434	6	1336 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(27):24466-24474 Angata T; Kerr SC; Greaves DR; Varki NM; Crocker PR; Varki A Cloning and characterization of human Siglec-11 - A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia	8	1
435	2	1500 2002 MOLECULAR BIOLOGY AND EVOLUTION 19(7):1143-1153 Payseur BA; Cutter AD; Nachman MW Searching for evidence of positive selection in the human genome using patterns of microsatellite variability	8	0
436	8	1556 2002 NATURE 420(6912):218-223 Koonin EV; Wolf YI; Karev GP The structure of the protein universe and genome evolution	8	1
437	5	1653 2002 NUCLEIC ACIDS RESEARCH 30(17):3754-3766 Xu Q; Modrek B; Lee C Genome-wide detection of tissue-specific alternative splicing in the human transcriptome	8	4
438	8	1674 2002 PHARMACOGENOMICS 3(3):379-391 Judson R; Salisbury B; Schneider J; Windemuth A; Stephens JC How many SNPs does a genome-wide haplotype map require?	8	1
439	2	1711 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(1):327-332 Greally JM Short interspersed transposable elements (SINEs) are excluded from imprinted regions in the human genome	8	3
440	3	1724 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(7):4145-4146 Myers EW; Sutton GG; Smith HO; Adams MD; Venter JC On the sequencing and assembly of the human genome	8	6
441	1	13 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(5):1002-1012 Lefevre C; Jobard F; Caux F; Bouadjar B; Karaduman A; Heilig R; Lakhdar H; Wollenberg A; Verret JL; Weissenbach J; Ozguc M; Lathrop M; Prud'homme JF; Fischer J Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/thioesterase subfamily, in Chanarin-Dorfman syndrome	7	0
442	3	44 2001 ARCHIVES OF NEUROLOGY 58(11):1772-1778 Cravchik A; Subramanian G; Broder S; Venter JC Sequence analysis of the human genome - Implications for the understanding of nervous system function and disease	7	4
443	1	51 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 282(4):928-933 Bartes A; Bhakta S; Hemmerich S Sulfation of endothelial mucin by corneal keratan N- acetylglucosamine 6-O-sulfotransferase (GST-4 beta)	7	0
444	3	56 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 288(2):362-370 Popovici C; Leveugle M; Birnbaum D; Coulier F Coparalogy: Physical and functional clusterings in the human genome	7	3
445	2	94 2001 CANCER RESEARCH 61(18):6640-6648 Bullrich F; Fujii H; Calin G; Mabuchi H; Negrini M; Pekarsky Y; Rassenti L; Alder H; Reed JC; Keating MJ; Kipps TJ; Croce CM Characterization of the 13q14 tumor suppressor locus in CLL: Identification of ALT1, an alternative splice variant of the LEU2 gene	7	1
446	2	109 2001 CELLULAR AND MOLECULAR LIFE SCIENCES 58(14):2085-2097 Li D; Roberts R WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases	7	0
447	2	124 2001 CLINICAL CANCER RESEARCH 7(11):3416-3422 Whetstine JR; Gifford AJ; Witt T; Liu XY; Flatley RM; Norris M; Haber M; Taub JW; Ravindranath Y; Matherly LH Single nucleotide polymorphisms in the human reduced folate carrier: Characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers	7	0
448	3	146 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(4):334-339 Xenarios L; Eisenberg D Protein interaction databases	7	0
449	3	154 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):632-637 Segal DJ; Barbas CF Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins	7	2
450	2	165 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):652-659 Comeron JM What controls the length of noncoding DNA?	7	0
451	1	211 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(24):6435-6448 Titeux M; Brocheriou V; Xue ZG; Gao J; Pellissier JF; Guicheney P; Paulin D; Li ZL Human synemin gene generates splice variants encoding two distinct intermediate filament proteins	7	2
452	3	224 2001 EXPERT OPINION ON INVESTIGATIONAL DRUGS 10(7):1327-1344 Sawyer T; Boyce B; Dalgarno D; Iuliucci J Src inhibitors: genomics to therapeutics	7	2
453	1	238 2001 GENE 270(1-2):17-30 Lecompte O; Thompson JD; Plewniak F; Thierry JC; Poch O Multiple alignment of complete sequences (MACS) in the post- genomic era	7	0
454	4	245 2001 GENE 276(1-2):25-31 Clay O; Bernardi G Compositional heterogeneity within and among isochores in mammalian genomes - II. Some general comments	7	5
455	1	253 2001 GENE 278(1-2):63-79 Martin SC; Russek SJ; Farb DH Human GABA(B)R genomic structure: evidence for splice variants in GABA(B)R1 but not GABA(B)R2	7	0
456	2	286 2001 GENOME RESEARCH 11(8):1353-1364 Caceres M; Puig M; Ruiz A Molecular characterization of two natural hotspots in the Drosophila buzzatii genome induced by transposon insertions	7	2
457	2	290 2001 GENOME RESEARCH 11(9):1520-1526 Beaudoing E; Gautheret D Identification of alternate polyadenylation sites and analysis of their tissue distribution using EST data	7	2
458	1	301 2001 GENOME RESEARCH 11(11):1848-1853 Hide WA; Babenko VN; van Heusden PA; Seoighe C; Kelso JF The contribution of exon-skipping events on chromosome 22 to protein coding diversity	7	6
459	1	306 2001 GENOME RESEARCH 11(11):1952-1957 Wheelan SJ; Church DM; Ostell JM Spidey: A tool for mRNA-to-genomic alignments	7	3
460	1	373 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(42):38956-38965 Velentza AV; Schumacher AM; Weiss C; Egli M; Watterson DM A protein kinase associated with apoptosis and tumor suppression - Structure, activity, and discovery of peptide substrates	7	0
461	2	375 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(43):40041-40049 Nagaike T; Suzuki T; Tomari Y; Takemoto-Hori C; Negayama F; Watanabe K; Ueda T Identification and characterization of mammalian mitochondrial tRNA nucleotidyltransferases	7	0
462	2	378 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(46):43216-43220 Zhang Q; Fan JS; Zhang MJ Interdomain chaperoning between PSD-95, Dlg, and Zo-1 (PDZ) domains of glutamate receptor-interacting proteins	7	1
463	2	396 2001 JOURNAL OF GENERAL VIROLOGY 82():2083-2093 Gardner JD; Tscharke DC; Reading PC; Smith GL Vaccinia virus semaphorin A39R is a 50-55 kDa secreted glycoprotein that affects the outcome of infection in a murine intradermal model	7	0
464	2	415 2001 JOURNAL OF PATHOLOGY 195(1):87-96 Frantz GD; Pham TQ; Peale FV; Hillan KJ Detection of novel gene expression in paraffin-embedded tissues by isotopic in situ hybridization in tissue microarrays	7	1
465	2	421 2001 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 123(37):8887-8894 Butler JH; Cronin M; Anderson KM; Biddison GM; Chatelain F; Cummer M; Davi DJ; Fisher L; Frauendorf AW; Frueh FW; Gjerstad C; Harper TF; Kernahan SD; Long DQ; Pho M; Walker JA; Brennan TM In situ synthesis of oligonucleotide arrays by using surface tension	7	0
466	1	449 2001 MOLECULAR AND CELLULAR NEUROSCIENCE 18(1):80-90 Hartmann AM; Rujescu D; Giannakouros T; Nikolakaki E; Goedert M; Mandelkow EM; Gao QS; Andreadis A; Stamm S Regulation of alternative splicing of human tau exon 10 by phosphorylation of splicing factors	7	2
467	2	517 2001 NATURE GENETICS 29(4):377-378 Holmes SE; O'Hearn E; Rosenblatt A; Callahan C; Hwang HS; Ingersoll-Ashworth RG; Fleisher A; Stevanin G; Brice A; Potter NT; Ross CA; Margolis RL A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease-like 2	7	0
468	2	538 2001 NATURE REVIEWS GENETICS 2(9):681-689 Kim SK HTTP ://C-elegans: Mining the functional genomic landscape	7	1
469	2	590 2001 PLANT CELL 13(10):2297-2317 Woo YM; Hu DWN; Larkins BA; Jung R Genomics analysis of genes expressed in maize endosperm identifies novel seed proteins and clarifies patterns of zein gene expression	7	0
470	1	614 2001 PROTEOMICS 1(10):1249-1263 Seow TK; Liang RCMY; Leow CK; Chung MCM Hepatocellular carcinoma: From bedside to proteomics	7	0
471	2	646 2001 SCIENCE 294(5547):1669-1670 Kwok PY Genomics - Genetic association by whole-genome analysis?	7	2
472	2	670 2001 TRENDS IN BIOTECHNOLOGY 19(10):S17-S22 Choudhary JS; Blackstock WP; Creasy DM; Cottrell JS Matching peptide mass spectra to EST and genomic DNA databases	7	2
473	3	678 2001 TRENDS IN BIOTECHNOLOGY 19(12):511-518 Ko MSH Embryogenomics: developmental biology meets genomics	7	2
474	2	679 2001 TRENDS IN BIOTECHNOLOGY 19(12):519-523 Nebert DW; Bingham E Pharmacogenomics: out of the lab and into the community	7	2
475	7	753 2002 AMERICAN JOURNAL OF HUMAN GENETICS 71(2):312-326 Myers JS; Vincent BJ; Udall H; Watkins WS; Morrish TA; Kilroy GE; Swergold GD; Henke J; Henke L; Moran JV; Jorde LB; Batzer MA A comprehensive analysis of recently integrated human Ta L1 elements	7	5
476	1	822 2002 BIOCHEMISTRY 41(2):462-474 Kashlan OB; Scott CP; Lear JD; Cooperman BS A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase. Functional consequences of ATP- and dATP-induced oligomerization of the large subunit	7	0
477	1	898 2002 CANCER RESEARCH 62(2):367-370 Nihei N; Kouprina N; Larionov V; Oshima J; Martin GM; Ichikawa T; Barrett JC Functional evidence for a metastasis suppressor gene for rat prostate cancer within a 60-kilobase region on human chromosome 8p21-p12	7	0
478	3	908 2002 CELL 109(7):807-809 Adachi N; Lieber MR Bidirectional gene organization: A common architectural feature of the human genome	7	0
479	2	1086 2002 FEBS LETTERS 516(1-3):133-138 Poola I; Abraham J; Baldwin K Identification of ten exon deleted ER beta mRNAs in human ovary, breast, uterus and bone tissues: alternate splicing pattern of estrogen receptor beta mRNA is distinct from that of estrogen receptor alpha	7	0
480	1	1170 2002 GENOME RESEARCH 12(1):47-56 Doerks T; Copley RR; Schultz J; Ponting CP; Bork P Systematic identification of novel protein domain families associated with nuclear functions	7	2
481	1	1171 2002 GENOME RESEARCH 12(1):57-66 Bolshakov VN; Topalis P; Blass C; Kokoza E; della Torre A; Kafatos FC; Louis C A comparative genomic analysis of two distant diptera, the fruit fly, Drosophila melanogaster, and the malaria mosquito, Anopheles gambiae	7	3
482	1	1179 2002 GENOME RESEARCH 12(3):379-390 Yoshihama M; Uechi T; Asakawa S; Kawasaki K; Kato S; Higa S; Maeda N; Minoshima S; Tanaka T; Shimizu N; Kenmochi N The human ribosomal protein genes: Sequencing and comparative analysis of 73 genes	7	2
483	2	1190 2002 GENOME RESEARCH 12(6):885-893 Woischnik M; Moraes CT Pattern of organization of human mitochondrial pseudogenes in the nuclear genome	7	0
484	4	1191 2002 GENOME RESEARCH 12(6):894-908 Chureau C; Prissette M; Bourdet A; Barbe V; Cattolico L; Jones L; Eggen A; Avner P; Duret L Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine	7	2
485	4	1194 2002 GENOME RESEARCH 12(7):1060-1067 Sorek R; Ast G; Graur D Alu-containing exons are alternatively spliced	7	4
486	3	1229 2002 GENOMICS 79(3):333-343 Ottolenghi C; Fellous M; Barbieri M; McElreavey K Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination	7	0
487	7	1272 2002 HUMAN MOLECULAR GENETICS 11(10):1153-1160 Young JM; Trask BJ The sense of smell: genomics of vertebrate odorant receptors	7	1
488	2	1384 2002 JOURNAL OF IMMUNOLOGY 169(8):4088-4093 Harton JA; Linhoff MW; Zhang JH; Ting JPY Cutting edge: CATERPILLER: A large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains	7	0
489	7	1400 2002 JOURNAL OF MOLECULAR BIOLOGY 318(5):1155-1174 Harrison PM; Gerstein M Studying Genomes through the aeons: Protein families, pseudogenes and proteome evolution	7	3
490	1	1436 2002 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 13(1):80-85 Iwai N; Baba S; Mannami T; Ogihara T; Ogata J Association of a sodium channel a subunit promoter variant with blood pressure	7	0
491	2	1439 2002 JOURNAL OF VIROLOGY 76(5):2192-2198 Chen WB; Burgess S; Golling G; Amsterdam A; Hopkins N High-throughput selection of retrovirus producer cell lines leads to markedly improved efficiency of germ line- transmissible insertions in zebra fish	7	0
492	2	1478 2002 MOLECULAR & CELLULAR PROTEOMICS 1(3):204-212 Shevchenko A; Schaft D; Roguev A; Pijnappel WWMP; Stewart AF; Shevchenko A Deciphering protein complexes and protein interaction networks by tandem affinity purification and mass spectrometry - Analytical perspective	7	0
493	2	1482 2002 MOLECULAR AND CELLULAR BIOLOGY 22(5):1402-1411 Korotkov KV; Novoselov SV; Hatfield DL; Gladyshev VN Mammalian selenoprotein in which selenocysteine (Sec) incorporation is supported by a new form of Sec insertion sequence element	7	1
494	2	1524 2002 MOLECULAR GENETICS AND METABOLISM 75(1):1-16 Fruhwald MC; Plass C Global and gene-specific methylation patterns in cancer: Aspects of tumor biology and clinical potential	7	0
495	1	1594 2002 NATURE GENETICS 32(3):432-437 Cowles CR; Hirschhorn JN; Altshuler D; Lander ES Detection of regulatory variation in mouse genes	7	0
496	2	1629 2002 NUCLEIC ACIDS RESEARCH 30(1):137-141 Hodges PE; Carrico PM; Hogan JD; O'Neill KE; Owen JJ; Mangan M; Davis BP; Brooks JE; Garrels JI Annotating the human proteome: the Human Proteome Survey Database (HumanPSD (TM)) and an in-depth target database for G protein-coupled receptors (GPCR-PD (TM)) from Incyte Genomics	7	3
497	1	1641 2002 NUCLEIC ACIDS RESEARCH 30(5):1169-1175 Zhang JZ; Dyer KD; Rosenberg HF RNase 8, a novel RNase A superfamily ribonuclease expressed uniquely in placenta	7	0
498	3	1679 2002 PHARMACOLOGY & THERAPEUTICS 93(2-3):79-98 Fabbro D; Ruetz S; Buchdunger E; Cowan-Jacob SW; Fendrich G; Liebetanz J; Mestan J; O'Reilly T; Traxler P; Chaudhuri B; Fretz H; Zimmermann J; Meyer T; Caravatti G; Furet P; Manley PW Protein kinases as targets for anticancer agents: from inhibitors to useful drugs	7	2
499	1	1698 2002 PLANT CELL 14(7):1441-1456 Van der Hoeven R; Ronning C; Giovannoni J; Martin G; Tanksley S Deductions about the number, organization, and evolution of genes in the tomato genome based on analysis of a large expressed sequence tag collection and selective genomic sequencing	7	0
500	2	1699 2002 PLANT CELL 14(8):1691-1704 Cheng ZK; Dong FG; Langdon T; Shu OY; Buell CR; Gu MH; Blattner FR; Jiang JM Functional rice centromeres are marked by a satellite repeat and a centromere-specific retrotransposon	7	0

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