#	Cited nodes	Nodes / Authors	GCS	LCS
101	2	456 2001 MOLECULAR BIOLOGY AND EVOLUTION 18(11):2032-2039 Lercher MJ; Williams EJB; Hurst LD Local similarity in evolutionary rates extends over whole chromosomes in human-rodent and mouse-rat comparisons: Implications for understanding the mechanistic basis of the male mutation bias	23	7
102	1	461 2001 MOLECULAR CELL 8(6):1351-1361 Zhu J; Mayeda A; Krainer AR Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer- bound SR proteins	22	7
103	2	471 2001 NATURE 409(6822):824-826 Wolfsberg TG; McEntyre J; Schuler GD Guide to the draft human genome	12	7
104	1	473 2001 NATURE 409(6822):844-846 Murray AW; Marks D Can sequencing shed light on cell cycling?	16	7
105	1	512 2001 NATURE GENETICS 29(2):201-205 Hudson TJ; Church DM; Greenaway S; Nguyen H; Cook A; Steen RG; Van Etten WJ; Castle AB; Strivens MA; Trickett P; Heuston C; Davison C; Southwell A; Hardisty R; Varela-Carver A; Haynes AR; Rodriguez-Tome P; Doi H; Ko MSH; Pontius J; Schriml L; Wagner L; Maglott D; Brown SDM; Lander ES; Schuler G; Denny P A radiation hybrid map of mouse genes	14	7
106	1	601 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(20):11399-11404 Hayakawa T; Satta Y; Gagneux P; Varki A; Takahata N Alu-mediated inactivation of the human CMP-N-acetylneuraminic acid hydroxylase gene	9	7
107	2	626 2001 SCIENCE 291(5507):1219-+ Paabo S Genomics and society - The human genome and our view of ourselves	18	7
108	2	628 2001 SCIENCE 291(5507):1257-+ Galas DJ Sequence interpretation - Making sense of the sequence	11	7
109	3	1626 2002 NUCLEIC ACIDS RESEARCH 30(1):21-26 Stoesser G; Baker W; van den Broek A; Camon E; Garcia-Pastor M; Kanz C; Kulikova T; Leinonen R; Lin Q; Lombard V; Lopez R; Redaschi N; Stoehr P; Tuli MA; Tzouvara K; Vaughan R The EMBL Nucleotide Sequence Database	56	7
110	4	1797 2002 SCIENCE 298(5601):2157-2167 Dehal P; Satou Y; Campbell RK; Chapman J; Degnan B; De Tomaso A; Davidson B; Di Gregorio A; Gelpke M; Goodstein DM; Harafuji N; Hastings KEM; Ho I; Hotta K; Huang W; Kawashima T; Lemaire P; Martinez D; Meinertzhagen IA; Necula S; Nonaka M; Putnam N; Rash S; Saiga H; Satake M; Terry A; Yamada L; Wang HG; Awazu S; Azumi K; Boore J; Branno M; Chin-bow S; DeSantis R; Doyle S; Francino P; Keys DN; Haga S; Hayashi H; Hino K; Imai KS; Inaba K; Kano S; Kobayashi K; Kobayashi M; Lee BI; Makabe KW; Manohar C; Matassi G; Medina M; Mochizuki Y; Mount S; Morishita T; Miura S; Nakayama A; Nishizaka S; Nomoto H; Ohta F; Oishi K; Rigoutsos I; Sano M; Sasaki A; Sasakura Y; Shoguchi E; Shin-i T; Spagnuolo A; Stainier D; Suzuki MM; Tassy O; Takatori N; Tokuoka M; Yagi K; Yoshizaki F; Wada S; Zhang C; Hyatt PD; Larimer F; Detter C; Doggett N; Glavina T; Hawkins T; Richardson P; Lucas S; Kohara Y; Levine M; Satoh N; Rokhsar DS The draft genome of Ciona intestinalis: Insights into chordate and vertebrate origins	25	7
111	2	268 2001 GENETICS 159(2):907-911 Galtier N; Piganeau G; Mouchiroud D; Duret L GC-content evolution in mammalian genomes: The biased gene conversion hypothesis	13	6
112	1	301 2001 GENOME RESEARCH 11(11):1848-1853 Hide WA; Babenko VN; van Heusden PA; Seoighe C; Kelso JF The contribution of exon-skipping events on chromosome 22 to protein coding diversity	7	6
113	2	453 2001 MOLECULAR BIOLOGY AND EVOLUTION 18(9):1611-1630 Mattick JS; Gagen MJ The evolution of controlled multitasked gene networks: The role of introns and other noncoding RNAs in the development of complex organisms	21	6
114	2	530 2001 NATURE REVIEWS GENETICS 2(4):302-312 Kumar A; Snyder M Emerging technologies in yeast genomics	30	6
115	2	696 2001 TRENDS IN GENETICS 17(11):637-645 Hacia JG Genome of the apes	17	6
116	2	841 2002 BIOINFORMATICS 18(3):440-445 Ma B; Tromp J; Li M PatternHunter: faster and more sensitive homology search	12	6
117	3	906 2002 CELL 109(3):283-284 Daly MJ Estimating the human gene count	8	6
118	4	1083 2002 FEBS LETTERS 511(1-3):165-169 Pavlicek A; Paces J; Clay O; Bernardi G A compact view of isochores in the draft human genome sequence	9	6
119	4	1168 2002 GENOME RESEARCH 12(1):3-15 DeSilva U; Elnitski L; Idol JR; Doyle JL; Gan WN; Thomas JW; Schwartz S; Dietrich NL; Beckstrom-Sternberg SM; McDowell JC; Blakesley RW; Bouffard GG; Thomas PJ; Touchman JW; Miller W; Green ED Generation and comparative analysis of similar to 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome	13	6
120	3	1230 2002 GENOMICS 79(3):413-422 Buzdin A; Khodosevich K; Mamedov I; Vinogradova T; Lebedev Y; Hunsmann G; Sverdlov E A technique for genome-wide identification of differences in the interspersed repeats integrations between closely related genomes and its application to detection of human-specific integrations of HERV-K LTRs	6	6
121	1	1409 2002 JOURNAL OF MOLECULAR EVOLUTION 54(1):129-133 Piganeau G; Mouchiroud D; Duret L; Gautier C Expected relationship between the silent substitution rate and the GC content: Implications for the evolution of isochores	6	6
122	3	1566 2002 NATURE BIOTECHNOLOGY 20(4):353-358 Yeakley JM; Fan JB; Doucet D; Luo L; Wickham E; Ye Z; Chee MS; Fu XD Profiling alternative splicing on fiber-optic arrays	20	6
123	4	1599 2002 NATURE REVIEWS DRUG DISCOVERY 1(9):727-730 Hopkins AL; Groom CR The druggable genome	21	6
124	2	1637 2002 NUCLEIC ACIDS RESEARCH 30(1):328-331 Suzuki Y; Yamashita R; Nakai K; Sugano S DBTSS: DataBase of human transcriptional start sites and full- length cDNAs	12	6
125	3	1724 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(7):4145-4146 Myers EW; Sutton GG; Smith HO; Adams MD; Venter JC On the sequencing and assembly of the human genome	8	6
126	2	1791 2002 SCIENCE 296(5569):907-910 Clark TA; Sugnet CW; Ares M Genomewide analysis of mRNA processing in yeast using splicing- specific microarrays	20	6
127	2	58 2001 BIOCHEMICAL PHARMACOLOGY 62(10):1311-1336 Clarke PA; Poele RT; Wooster R; Workman P Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential	31	5
128	2	160 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(3):247-257 Sreekumar KR; Aravind L; Koonin EV Computational analysis of human disease-associated genes and their protein products	8	5
129	4	245 2001 GENE 276(1-2):25-31 Clay O; Bernardi G Compositional heterogeneity within and among isochores in mammalian genomes - II. Some general comments	7	5
130	2	278 2001 GENOME RESEARCH 11(5):667-670 Makalowski W Are we polyploids? A brief history of one hypothesis	11	5
131	2	293 2001 GENOME RESEARCH 11(10):1660-1676 Meyers BC; Tingley SV; Morgante M Abundance, distribution, and transcriptional activity of repetitive elements in the maize genome	16	5
132	2	297 2001 GENOME RESEARCH 11(10):1758-1765 Suzuki H; Fukunishi Y; Kagawa I; Saito R; Oda H; Endo T; Kondo S; Bono H; Okazaki Y; Hayashizaki Y Protein-protein interaction panel using mouse full-length cDNAs	16	5
133	2	318 2001 GENOMICS 78(1-2):46-54 Reymond A; Friedli M; Henrichsen CN; Chapot F; Deutsch S; Ucla C; Rossier C; Lyle R; Guipponi M; Antonarakis SE From PREDs and open reading frames to cDNA isolation: Revisiting the human chromosome 21 transcription map	8	5
134	3	335 2001 HUMAN MOLECULAR GENETICS 10(24):2833-2839 Eisenbarth I; Striebel AM; Moschgath E; Vogel W; Assum G Long-range sequence composition mirrors linkage disequilibrium pattern in a 1.13 Mb region of human chromosome 22	11	5
135	1	497 2001 NATURE BIOTECHNOLOGY 19(3):196-196 Sorek R; Amitai M Piecing together the significance of splicing	8	5
136	2	519 2001 NATURE GENETICS 29(4):459-464 Hodgson G; Hager JH; Volik S; Hariono S; Wernick M; Moore D; Albertson DG; Pinkel D; Collins C; Hanahan D; Gray JW Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas	30	5
137	3	520 2001 NATURE GENETICS 29(4):487-489 Hughes JF; Coffin JM Evidence for genomic rearrangements mediated by human endogenous retroviruses during primate evolution	9	5
138	2	546 2001 NATURE REVIEWS NEUROSCIENCE 2(12):861-870 Heintz N Bac to the future: The use of bac transgenic mice for neuroscience research	14	5
139	2	592 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(8):4277-4278 Hazbun TR; Fields S Networking proteins in yeast	19	5
140	1	599 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(19):10787-10792 Staunton JE; Slonim DK; Coller HA; Tamayo P; Angelo MJ; Park J; Scherf U; Lee JK; Reinhold WO; Weinstein JN; Mesirov JP; Lander ES; Golub TR Chemosensitivity prediction by transcriptional profiling	39	5
141	2	607 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(25):14503-14508 Chiaromonte F; Yang S; Elnitski L; Yap VB; Miller W; Hardison RC Association between divergence and interspersed repeats in mammalian noncoding genomic DNA	8	5
142	2	643 2001 SCIENCE 294(5540):86-87 Avise JC Evolving genomic metaphors: A new look at the language of DNA	8	5
143	2	645 2001 SCIENCE 294(5545):1343-1346 Saha S; Bardelli A; Buckhaults P; Velculescu VE; Rago C; St Croix B; Romans KE; Choti MA; Lengauer C; Kinzler KW; Vogelstein B A phosphatase associated with metastasis of colorectal cancer	44	5
144	7	753 2002 AMERICAN JOURNAL OF HUMAN GENETICS 71(2):312-326 Myers JS; Vincent BJ; Udall H; Watkins WS; Morrish TA; Kilroy GE; Swergold GD; Henke J; Henke L; Moran JV; Jorde LB; Batzer MA A comprehensive analysis of recently integrated human Ta L1 elements	7	5
145	4	1172 2002 GENOME RESEARCH 12(1):67-80 Crosier M; Viggiano L; Guy J; Misceo D; Stones R; Wei WB; Hearn T; Ventura M; Archidiacono N; Rocchi M; Jackson MS Human paralogs of KIAA0187 were created through independent pericentromeric-directed and chromosome-specific duplication mechanisms	8	5
146	6	1604 2002 NATURE REVIEWS GENETICS 3(5):391-A396 Tabor HK; Risch NJ; Myers RM Candidate-gene approaches for studying complex genetic traits: practical considerations	27	5
147	2	1713 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(2):763-768 Markstein M; Markstein P; Markstein V; Levine MS Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo	35	5
148	2	1726 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(7):4465-4470 Su AI; Cooke MP; Ching KA; Hakak Y; Walker JR; Wiltshire T; Orth AP; Vega RG; Sapinoso LM; Moqrich A; Patapoutian A; Hampton GM; Schultz PG; Hogenesch JB Large-scale analysis of the human and mouse transcriptomes	33	5
149	4	1744 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(26):16899-16903 Strausberg RL; Feingold EA; Grouse LH; Derge JG; Klausner RD; Collins FS; Wagner L; Shenmen CM; Schuler GD; Altschul SF; Zeeberg B; Buetow KH; Schaefer CF; Bhat NK; Hopkins RF; Jordan H; Moore T; Max SI; Wang J; Hsieh F; Diatchenko L; Marusina K; Farmer AA; Rubin GM; Hong L; Stapleton M; Soares MB; Bonaldo MF; Casavant TL; Scheetz TE; Brownstein MJ; Usdin TB; Toshiyuki S; Carninci P; Prange C; Raha SS; Loquellano NA; Peters GJ; Abramson RD; Mullahy SJ; Bosak SA; McEwan PJ; McKernan KJ; Malek JA; Gunaratne PH; Richards S; Worley KC; Hale S; Garcia AM; Gay LJ; Hulyk SW; Villalon DK; Muzny DM; Sodergren EJ; Lu XH; Gibbs RA; Fahey J; Helton E; Ketteman M; Madan A; Rodrigues S; Sanchez A; Whiting M; Madan A; Young AC; Shevchenko Y; Bouffard GG; Blakesley RW; Touchman JW; Green ED; Dickson MC; Rodriguez AC; Grimwood J; Schmutz J; Myers RM; Butterfield YSN; Kryzywinski MI; Skalska U; Smailus DE; Schnerch A; Schein JE; Jones SJM; Marra MA; Mammalian Gene Collection MGC Pro Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences	6	5
150	2	9 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(3):516-527 Jenne DE; Tinschert S; Reimann H; Lasinger W; Thiel G; Hameister H; Kehrer-Sawatzki H Molecular characterization and gene content of breakpoint boundaries in patients with neurofibromatosis type 1 with 17q11.2 microdeletions	11	4
151	1	10 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(3):553-569 Wiltshire S; Hattersley AT; Hitman GA; Walker M; Levy JC; Sampson M; O'Rahilly S; Frayling TM; Bell JI; Lathrop GM; Bennett A; Dhillon R; Fletcher C; Groves CJ; Jones E; Prestwich P; Simecek N; Rao PVS; Wishart M; Foxon R; Howell S; Smedley D; Cardon LR; Menzel S; McCarthy MI A genomewide scan for loci predisposing to type 2 diabetes in a UK population (the Diabetes UK Warren 2 repository): Analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q	41	4
152	2	34 2001 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 2():343-372 Ideker T; Galitski T; Hood L A new approach to decoding life: Systems biology	34	4
153	3	44 2001 ARCHIVES OF NEUROLOGY 58(11):1772-1778 Cravchik A; Subramanian G; Broder S; Venter JC Sequence analysis of the human genome - Implications for the understanding of nervous system function and disease	7	4
154	2	71 2001 BIOINFORMATICS 17(10):878-889 Frith MC; Hansen U; Weng ZP Detection of cis-element clusters in higher eukaryotic DNA	18	4
155	2	118 2001 CHROMOSOME RESEARCH 9(7):541-567 Cremer M; von Hase J; Volm T; Brero A; Kreth G; Walter J; Fischer C; Solovei I; Cremer C; Cremer T Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells	18	4
156	1	193 2001 DRUG DISCOVERY TODAY 6(12):628-636 Harris S Transgenic knockouts as part of high-throughput, evidence-based target selection and validation strategies	6	4
157	1	206 2001 EMBO JOURNAL 20(19):5354-5360 Betts MJ; Guigo R; Agarwal P; Russell RB Exon structure conservation despite low sequence similarity: a relic of dramatic events in evolution?	10	4
158	4	209 2001 EMBO REPORTS 2(11):986-991 Mattick JS Non-coding RNAs: the architects of eukaryotic complexity	26	4
159	2	249 2001 GENE 276(1-2):73-81 Pesole G; Mignone F; Gissi C; Grillo G; Licciulli F; Liuni S Structural and functional features of eukaryotic mRNA untranslated regions	14	4
160	2	336 2001 HUMAN MUTATION 17(6):475-492 Gut IG Automation in genotyping of single nucleotide polymorphisms	35	4
161	2	402 2001 JOURNAL OF MOLECULAR BIOLOGY 307(2):683-706 Chasman D; Adams RM Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: Structure-based assessment of amino acid variation	22	4
162	2	487 2001 NATURE 411(6839):759-762 Downward J The ins and outs of signalling	27	4
163	2	500 2001 NATURE BIOTECHNOLOGY 19(5):440-445 Harrington JJ; Sherf B; Rundlett S; Jackson PD; Perry R; Cain S; Leventhal C; Thornton M; Ramachandran R; Whittington J; Lerner L; Costanzo D; McElligott K; Boozer S; Mays R; Smith E; Veloso N; Klika A; Hess J; Cothren K; Lo K; Offenbacher J; Danzig J; Ducar M Creation of genome-wide protein expression libraries using random activation of gene expression	13	4
164	1	600 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(20):11193-11198 Lim LP; Burge CB A computational analysis of sequence features involved in recognition of short introns	16	4
165	2	608 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(26):15203-15208 Nacht M; Dracheva T; Gao YH; Fujii T; Chen YD; Player A; Akmaev V; Cook B; Dufault M; Zhang M; Zhang W; Guo MZ; Curran J; Han S; Sidransky D; Buetow K; Madden SL; Jen J Molecular characteristics of non-small cell lung cancer	16	4
166	1	611 2001 PROTEIN EXPRESSION AND PURIFICATION 22(2):159-164 Lesley SA High-throughput proteomics: Protein expression and purification in the postgenomic world	26	4
167	2	661 2001 STRUCTURE 9(8):717-723 Wolfe SA; Grant RA; Elrod-Erickson M; Pabo CO Beyond the "recognition code": Structures of two Cys(2)His(2) zinc finger/TATA box complexes	16	4
168	9	967 2002 CURRENT OPINION IN CHEMICAL BIOLOGY 6(3):375-383 Roberts GC; Smith CWJ Alternative splicing: combinatorial output from the genome	10	4
169	2	1030 2002 DRUG DISCOVERY TODAY 7(4):235-246 Wise A; Gearing K; Rees S Target validation of G-protein coupled receptors	18	4
170	4	1137 2002 GENES & DEVELOPMENT 16(1):6-21 Bird A DNA methylation patterns and epigenetic memory	113	4
171	4	1159 2002 GENETICS 162(4):1837-1847 Duret L; Semon M; Piganeau G; Mouchiroud D; Galtier N Vanishing GC-rich isochores in mammalian genomes	5	4
172	4	1193 2002 GENOME RESEARCH 12(7):1048-1059 Lespinet O; Wolf YI; Koonin EV; Aravind L The role of lineage-specific gene family expansion in the evolution of eukaryotes	9	4
173	4	1194 2002 GENOME RESEARCH 12(7):1060-1067 Sorek R; Ast G; Graur D Alu-containing exons are alternatively spliced	7	4
174	5	1205 2002 GENOME RESEARCH 12(9):1350-1356 Smith NGC; Webster MT; Ellegren H Deterministic mutation rate variation in the human genome	9	4
175	3	1233 2002 GENOMICS 79(4):587-597 Rowen L; Young J; Birditt B; Kaur A; Madan A; Philipps DL; Qin SZ; Minx P; Wilson RK; Hood L; Graveley BR Analysis of the human neurexin genes: Alternative splicing and the generation of protein diversity	8	4
176	2	1270 2002 HUMAN MOLECULAR GENETICS 11(4):451-464 Clark F; Thanaraj TA Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human	8	4
177	2	1479 2002 MOLECULAR & CELLULAR PROTEOMICS 1(4):323-333 Griffin TJ; Gygi SP; Ideker T; Rist B; Eng J; Hood L; Aebersold R Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae	25	4
178	3	1602 2002 NATURE REVIEWS GENETICS 3(5):329-341 Feschotte C; Jiang N; Wessler SR Plant transposable elements: Where genetics meets genomics	14	4
179	5	1653 2002 NUCLEIC ACIDS RESEARCH 30(17):3754-3766 Xu Q; Modrek B; Lee C Genome-wide detection of tissue-specific alternative splicing in the human transcriptome	8	4
180	4	1718 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(5):2930-2935 Chen CF; Gentles AJ; Jurka J; Karlin S Genes, pseudogenes, and Alu sequence organization across human chromosomes 21 and 22	6	4
181	4	1725 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(7):4424-4429 Tanabe H; Muller S; Neusser M; von Hase J; Calcagno E; Cremer M; Solovei I; Cremer C; Cremer T Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates	18	4
182	3	1785 2002 SCIENCE 295(5552):127-131 Boulton SJ; Gartner A; Reboul J; Vaglio P; Dyson N; Hill DE; Vidal M Combined functional genomic maps of the C-elegans DNA damage response	29	4
183	2	7 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(1):159-178 Rannala B; Reeve JP High-resolution multipoint linkage-disequilibrium mapping in the context of a human genome sequence	13	3
184	1	11 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(3):582-589 Ardlie K; Liu-Cordero SN; Eberle MA; Daly M; Barrett J; Winchester E; Lander ES; Kruglyak L Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion	22	3
185	3	56 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 288(2):362-370 Popovici C; Leveugle M; Birnbaum D; Coulier F Coparalogy: Physical and functional clusterings in the human genome	7	3
186	2	72 2001 BIOINFORMATICS 17(10):988-996 Rzhetsky A; Gomez SM Birth of scale-free molecular networks and the number of distinct DNA and protein domains per genome	14	3
187	1	97 2001 CELL 105(2):173-176 Sternberg PW Working in the post-genomic C-elegans world	14	3
188	2	116 2001 CHINESE SCIENCE BULLETIN 46(23):1937-1942 Yu J; Hu SN; Wang J; Li SG; Wong KSG; Liu B; Deng Y; Dai L; Zhou Y; Zhang XQ; Cao ML; Liu J; Sun JD; Tang JB; Chen YJ; Huang XB; Lin W; Ye C; Tong W; Cong LJ; Geng JN; Han YJ; Li L; Li W; Hu GQ; Huang XG; Li WJ; Li J; Liu ZW; Li L; Liu JP; Qi QH; Liu JS; Li L; Wang XG; Lu H; Wu TT; Zhu M; Ni PX; Han H; Dong W; Ren XY; Feng XL; Cui P; Li XR; Wang H; Xu X; Zhai WX; Xu Z; Zhang JS; He SJ; Zhang JG; Xu JC; Zhang KL; Zheng XW; Dong JH; Zeng WY; Tao L; Chen XW; He J; Liu DF; Tian W; Tian CG; Xia HG; Li G; Gao H; Li P; Chen W; Wang XD; Zhang Y; Hu JF; Wang J; Liu S; Yang J; Zhang GY; Xiong YQ; Li ZJ; Mao L; Zhou CS; Zhu Z; Chen RS; Hao BL; Zheng WM; Chen SY; Guo W; Li GJ; Liu SQ; Huang GY; Tao M; Wang J; Zhu LH; Yuan LP; Yang HM A draft sequence of the rice (Oryza sativa ssp indica) genome	14	3
189	2	119 2001 CHROMOSOME RESEARCH 9(7):569-584 Habermann FA; Cremer M; Walter J; Kreth G; von Hase J; Bauer K; Wienberg J; Cremer C; Cremer T; Solovei I Arrangements of macro- and microchromosomes in chicken cells	13	3
190	2	140 2001 CURRENT BIOLOGY 11(22):R900-R901 Brookfield JFY Selection on Alu sequences?	3	3
191	2	153 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):626-631 Walke DW; Han CS; Shaw J; Wann E; Zambrowicz B; Sands A In vivo drug target discovery: identifying the best targets from the genome	5	3
192	1	161 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(3):268-273 Brown SDM; Balling R Systematic approaches to mouse mutagenesis	25	3
193	4	167 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):681-684 Sankoff D Gene and genome duplication	11	3
194	9	276 2001 GENOME RESEARCH 11(5):645-651 Green ED; Chakravarti A The human genome sequence expedition: Views from the "Base Camp"	6	3
195	2	285 2001 GENOME RESEARCH 11(7):1290-1295 Tapper WJ; Morton NE; Dunham I; Ke XY; Collins A A sequence-based integrated map of chromosome 22	8	3
196	2	299 2001 GENOME RESEARCH 11(11):1807-1816 Chen R; Bouck JB; Weinstock GM; Gibbs RA Comparing vertebrate whole-genome shotgun reads to the human genome	5	3
197	1	305 2001 GENOME RESEARCH 11(11):1935-1943 Kwitek AE; Tonellato PJ; Chen D; Gullings-Handley J; Cheng YJS; Twigger S; Scheetz TE; Casavant TL; Stoll M; Nobrega MA; Shiozawa M; Soares MB; Sheffield VC; Jacob HJ Automated construction of high-density comparative maps between rat, human, and mouse	12	3
198	1	306 2001 GENOME RESEARCH 11(11):1952-1957 Wheelan SJ; Church DM; Ostell JM Spidey: A tool for mRNA-to-genomic alignments	7	3
199	1	313 2001 GENOMICS 76(1-3):110-116 Landry JR; Medstrand P; Mager DL Repetitive elements in the 5 ' untranslated region of a human zinc-finger gene modulate transcription and translation efficiency	6	3
200	2	316 2001 GENOMICS 77(3):117-118 Rogers J; Bradley A The mouse genome sequence: Status and prospects	5	3

#	Cited nodes	Nodes / Authors	GCS	LCS
201	1	329 2001 HUMAN MOLECULAR GENETICS 10(18):1995-2011 Sutherland HGE; Mumford GK; Newton K; Ford LV; Farrall R; Dellaire G; Caceres JF; Bickmore WA Large-scale identification of mammalian proteins localized to nuclear sub-compartments	14	3
202	3	331 2001 HUMAN MOLECULAR GENETICS 10(20):2209-2214 Goodstadt L; Ponting CR Sequence variation and disease in the wake of the draft human genome	6	3
203	2	342 2001 IMMUNITY 15(3):337-349 Glusman G; Rowen L; Lee I; Boysen C; Roach JC; Smit AFA; Wang K; Koop BF; Hood L Comparative genomics of the human and mouse T cell receptor loci	16	3
204	1	348 2001 IMMUNOLOGY 103(2):137-145 Crocker PR; Varki A Siglecs in the immune system	31	3
205	4	381 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(48):45128-45136 Angata T; Hingorani R; Varki NM; Varki A Cloning and characterization of a novel mouse Siglec, mSiglec-F - Differential evolution of the mouse and human (CD33) Siglec- 3-related gene clusters	11	3
206	2	388 2001 JOURNAL OF CELL SCIENCE 114(18):3219-3231 Harris BZ; Lim WA Mechanism and role of PDZ domains in signaling complex assembly	64	3
207	2	401 2001 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 33(10):1879-1886 Dempsey AA; Dzau VJ; Liew CC Cardiovascular genomics: Estimating the total number of genes expressed in the human cardiovascular system	11	3
208	1	418 2001 JOURNAL OF STRUCTURAL BIOLOGY 134(2-3):191-203 Lupas AN; Ponting CP; Russell RB On the evolution of protein folds: Are similar motifs in different protein folds the result of convergence, insertion, or relics of an ancient peptide world?	14	3
209	2	491 2001 NATURE 412(6847):580-582 Chicurel M Faster, better, cheaper genotyping	10	3
210	2	506 2001 NATURE GENETICS 27(4):383-391 Kuehl P; Zhang J; Lin Y; Lamba J; Assem M; Schuetz J; Watkins PB; Daly A; Wrighton SA; Hall SD; Maurel P; Relling M; Brimer C; Yasuda K; Venkataramanan R; Strom S; Thummel K; Boguski MS; Schuetz E Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression	113	3
211	1	508 2001 NATURE GENETICS 28(3):241-249 Mitchell KJ; Pinson KI; Kelly OG; Brennan J; Zupicich L; Scherz P; Leighton PA; Goodrich LV; Lu XW; Avery BJ; Tate P; Dill K; Pangilinan E; Wakenight P; Tessier-Lavigne M; Skarnes WC Functional analysis of secreted and transmembrane proteins critical to mouse development	36	3
212	1	537 2001 NATURE REVIEWS GENETICS 2(8):597-606 Hurst GDD; Werren JH The role of selfish genetic elements in eukaryotic evolution	13	3
213	2	555 2001 NEW ENGLAND JOURNAL OF MEDICINE 344(18):1392-1393 Schwartz RS Racial profiling in medical research.	43	3
214	2	593 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(12):6759-6764 Fischer SEJ; Wienholds E; Plasterk RHA Regulated transposition of a fish transposon in the mouse germ line	24	3
215	2	674 2001 TRENDS IN BIOTECHNOLOGY 19(7):266-272 Maggio ET; Ramnarayan K Recent developments in computational proteomics	13	3
216	2	694 2001 TRENDS IN GENETICS 17(9):541-545 Peri S; Ibarrola N; Blagoev B; Mann M; Pandey A Common pitfalls in bioinformatics-based analyses: look before you leap	4	3
217	2	746 2002 AMERICAN JOURNAL OF HUMAN GENETICS 70(3):593-603 Gretarsdottir S; Sveinbjornsdottir S; Jonsson HH; Jakobsson F; Einarsdottir E; Agnarsson U; Shkolny D; Einarsson G; Gudjonsdottir HM; Valdimarsson EM; Einarsson OB; Thorgeirsson G; Hadzic R; Jonsdottir S; Reynisdottir ST; Bjarnadottir SM; Gudmundsdottir T; Gudlaugsdottir GJ; Gill R; Lindpaintner K; Sainz J; Hannesson HH; Sigurdsson GT; Frigge ML; Kong A; Gudnason V; Stefansson K; Gulcher JR Localization of a susceptibility gene for common forms of stroke to 5q12	18	3
218	2	792 2002 ANNUAL REVIEW OF NEUROSCIENCE 25():1-50 Cowan WM; Kopnisky KL; Hyman SE The human genome project and its impact on psychiatry	8	3
219	2	911 2002 CELL 110(4):521-529 Schroder ARW; Shinn P; Chen HM; Berry C; Ecker JR; Bushman F HIV-1 integration in the human genome favors active genes and local hotspots	27	3
220	1	1049 2002 EMBO JOURNAL 21(3):408-417 Takahashi H; Fujiwara H Transplantation of target site specificity by swapping the endonuclease domains of two LINEs	5	3
221	4	1085 2002 FEBS LETTERS 513(1):129-134 Copley RR; Doerks T; Letunic I; Bork P Protein domain analysis in the era of complete genomes	3	3
222	1	1171 2002 GENOME RESEARCH 12(1):57-66 Bolshakov VN; Topalis P; Blass C; Kokoza E; della Torre A; Kafatos FC; Louis C A comparative genomic analysis of two distant diptera, the fruit fly, Drosophila melanogaster, and the malaria mosquito, Anopheles gambiae	7	3
223	4	1180 2002 GENOME RESEARCH 12(3):391-399 Pavlicek A; Paces J; Elleder D; Hejnar J Processed Pseudogenes of human endogenous retroviruses generated by LINEs: Their integration, stability, and distribution	5	3
224	4	1185 2002 GENOME RESEARCH 12(5):669-671 Mardis E; McPherson J; Martienssen R; Wilson RK; McCombie WR What is finished, and why does it matter	5	3
225	7	1187 2002 GENOME RESEARCH 12(5):729-738 Park SS; Stankiewicz P; Bi WM; Shaw C; Lehoczky J; Dewar K; Birren B; Lupski JR Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs	10	3
226	3	1188 2002 GENOME RESEARCH 12(5):785-794 Xie HQ; Wasserman A; Levine Z; Novik A; Grebinskiy V; Shoshan A; Mintz L Large-scale protein annotation through gene ontology	6	3
227	11	1207 2002 GENOME RESEARCH 12(10):1466-1482 Zhang ZL; Harrison P; Gerstein M Identification and analysis of over 2000 ribosomal protein pseudogenes in the human genome	5	3
228	2	1326 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(8):5882-5890 Finta C; Zaphiropoulos PG Intergenic mRNA molecules resulting from trans-splicing	11	3
229	7	1400 2002 JOURNAL OF MOLECULAR BIOLOGY 318(5):1155-1174 Harrison PM; Gerstein M Studying Genomes through the aeons: Protein families, pseudogenes and proteome evolution	7	3
230	2	1567 2002 NATURE BIOTECHNOLOGY 20(4):376-380 Kawasaki H; Onuki R; Suyama E; Taira K Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries	18	3
231	5	1568 2002 NATURE BIOTECHNOLOGY 20(4):393-396 Cai WW; Mao JH; Chow CW; Damani S; Balmain A; Bradley A Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays	16	3
232	2	1576 2002 NATURE GENETICS 30(2):141-142 Weber G; Shendure J; Tanenbaum DM; Church GM; Meyerson M Identification of foreign gene sequences by transcript filtering against the human genome	4	3
233	3	1596 2002 NATURE GENETICS 32(4):655-660 Ostertag EM; DeBerardinis RJ; Goodier JL; Zhang Y; Yang N; Gerton GL; Kazazian HH A mouse model of human L1 retrotransposition	3	3
234	3	1614 2002 NEW ENGLAND JOURNAL OF MEDICINE 347(19):1512-1520 Guttmacher AE; Collins FS Genomic medicine - A primer	19	3
235	2	1625 2002 NUCLEIC ACIDS RESEARCH 30(1):1-12 Baxevanis AD The Molecular Biology Database Collection: 2002 update	12	3
236	2	1629 2002 NUCLEIC ACIDS RESEARCH 30(1):137-141 Hodges PE; Carrico PM; Hogan JD; O'Neill KE; Owen JJ; Mangan M; Davis BP; Brooks JE; Garrels JI Annotating the human proteome: the Human Proteome Survey Database (HumanPSD (TM)) and an in-depth target database for G protein-coupled receptors (GPCR-PD (TM)) from Incyte Genomics	7	3
237	2	1631 2002 NUCLEIC ACIDS RESEARCH 30(1):166-168 Kikuno R; Nagase T; Waki M; Ohara O HUGE: a database for human large proteins identified in the Kazusa cDNA sequencing project	10	3
238	2	1711 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(1):327-332 Greally JM Short interspersed transposable elements (SINEs) are excluded from imprinted regions in the human genome	8	3
239	1	1715 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(3):1665-1670 Bai JH; Wang P; Chapman ER C2A activates a cryptic Ca2+-triggered membrane penetration activity within the C2B domain of synaptotagmin I	11	3
240	2	1719 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(5):2942-2947 Jordan B; Charest A; Dowd JF; Blumenstiel JP; Yeh RF; Osman A; Housman DE; Landers JE Genome complexity reduction for SNP genotyping analysis	6	3
241	2	1736 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10335-10340 Jessani N; Liu YS; Humphrey M; Cravatt BF Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness	13	3
242	2	1737 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(16):10522-10527 Ovchinnikov I; Rubin A; Swergold GD Tracing the LINEs of human evolution	3	3
243	2	1741 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(20):12963-12968 Pollack JR; Sorlie T; Perou CM; Rees CA; Jeffrey SS; Lonning PE; Tibshirani R; Botstein D; Borresen-Dale AL; Brown PO Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors	23	3
244	6	1795 2002 SCIENCE 298(5591):149-159 Zdobnov EM; von Mering C; Letunic I; Torrents D; Suyama M; Copley RR; Christophides GK; Thomasova D; Holt RA; Subramanian GM; Mueller HM; Dimopoulos G; Law JH; Wells MA; Birney E; Charlab R; Halpern AL; Kokoza E; Kraft CL; Lai ZW; Lewis S; Louis C; Barillas-Mury C; Nusskern D; Rubin GM; Salzberg SL; Sutton GG; Topalis P; Wides R; Wincker P; Yandell M; Collins FH; Ribeiro J; Gelbart WM; Kafatos FC; Bork P Comparative genome and proteome analysis of anopheles gambiae and Drosophila melanogaster	18	3
245	2	1830 2002 TRENDS IN BIOTECHNOLOGY 20(4):160-166 Templin MF; Stoll D; Schrenk M; Traub PC; Vohringer CF; Joos TO Protein microarray technology	32	3
246	11	2021 2003 GENOME RESEARCH 13(1):73-80 Couronne O; Poliakov A; Bray N; Ishkhanov T; Ryaboy D; Rubin E; Pachter L; Dubchak I Strategies and tools for whole-genome alignments	3	3
247	13	2215 2003 NATURE 421(6923):601-U1 Heilig R; Eckenberg R; Petit JL; Fonknechten NR; Da Silva C; Cattolico L; Levy M; Barbe V; de Berardinis V; Ureta-Vidal A; Pelletier E; Vico V; Anthouard V; Rowen L; Madan A; Qin SZ; Sun H; Du H; Pepin K; Artiguenave F; Robert C; Cruaud C; Bruls T; Jaillon O; Friedlander L; Samson G; Brottier P; Cure S; Segurens B; Aniere F; Samain S; Crespeau H; Abbasi N; Alach N; Boscus D; Dickhoff R; Dors M; Dubois I; Friedman C; Gouyvenoux M; James R; Madan A; Malrey-Estrada B; Mangenot S; Martins N; Menard M; Oztas S; Ratcliffe A; Shaffer T; Trask B; Vacherle B; Bellemere C; Belser C; Besnard-Gonnet M; Bartol-Mavel D; Boutard M; Briez-Silla S; Combette S; Dufosse-Laurent V; Ferron C; Lechaplais C; Louesse C; Muselet D; Magdelenat G; Pateau E; Petit E; Sirvain-Trukniewicz P; Trybou A; Vega-Czarny N; Bataille E; Bluet E; Bordelais I; Dubois M; Dumont C; Guerin T; Haffray S; Hammadi R; Muanga J; Pellouin V; Robert D; Wunderle E; Gauguet G; Roy A; Sainte-Marthe L; Verdier J; Verdier-Discala C; Hillier L; Fulton L; McPherson J; Matsuda F; Wilson R; Scarpelli C; Gyapay G; Wincker P; Saurin W; Quetier F; Waterston R; Hood L; Weissenbach J The DNA sequence and analysis of human chromosome 14	4	3
248	2	20 2001 ANALYTICAL BIOCHEMISTRY 297(1):79-85 Knaust RKC; Nordlund P Screening for soluble expression of recombinant proteins in a 96-well format	6	2
249	2	21 2001 ANALYTICAL CHEMISTRY 73(9):1917-1926 Shevchenko A; Sunyaev S; Loboda A; Shevehenko A; Bork P; Ens W; Standing KG Charting the proteomes of organisms with unsequenced genomes by MALDI-quadrupole time of flight mass spectrometry and BLAST homology searching	29	2
250	3	35 2001 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 2():493-510 Mombaerts P The human repertoire of odorant receptor genes and pseudogenes	9	2
251	2	65 2001 BIOESSAYS 23(12):1131-1137 Wade PA Methyl CpG-binding transcriptional proteins and repression	20	2
252	2	84 2001 BLOOD 98(4):1127-1134 Nakajima T; Matsumoto K; Suto H; Tanaka K; Ebisawa M; Tomita H; Yuki K; Katsunuma T; Akasawa A; Hashida R; Sugita Y; Ogawa H; Ra C; Saito H Gene expression screening of human mast cells and eosinophils using high-density oligonucleotide probe arrays: abundant expression of major basic protein in mast cells	6	2
253	2	88 2001 BRITISH MEDICAL JOURNAL 322(7293):1031-1034 Mathew C Science medicine and the future - Postgenomic technologies: hunting the genes for common disorders	8	2
254	2	92 2001 CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 10(7):733-741 Risch N The genetic epidemiology of cancer: Interpreting family and twin studies and their implications for molecular genetic approaches	36	2
255	2	101 2001 CELL 106(4):391-394 Hastie ND Life, sex, and WT1 isoforms - Three amino acids can make all the difference	13	2
256	3	103 2001 CELL 106(5):619-632 Dong XZ; Han SK; Zylka MJ; Simon MI; Anderson DJ A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons	17	2
257	1	104 2001 CELL 107(1):13-16 Hamilton BA; Frankel WN Of mice and genome sequence	9	2
258	3	122 2001 CIRCULATION RESEARCH 89(11):1065-1072 Bang ML; Centner T; Fornoff F; Geach AJ; Gotthardt M; McNabb M; Witt CC; Labeit D; Gregorio CC; Granzier H; Labeit S The complete gene sequence of titin, expression of an unusual approximate to 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system	30	2
259	2	150 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(5):516-522 Roberts MA; Mutch DM; German JB Genomics: food and nutrition	6	2
260	3	154 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):632-637 Segal DJ; Barbas CF Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins	7	2
261	2	159 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(4):464-470 Caron PR; Mullican MD; Mashal RD; Wilson KP; Su MS; Murcko MA Chemogenomic approaches to drug discovery - Commentary	21	2
262	2	169 2001 CURRENT OPINION IN MOLECULAR THERAPEUTICS 3(3):229-234 Kole R; Sazani P Antisense effects in the cell nucleus: Modification of splicing	17	2
263	3	181 2001 DISEASE MARKERS 17(2):89-98 Chanock S Candidate genes and single nucleotide polymorphisms (SNPs) in the study of human disease	10	2
264	2	183 2001 DNA RESEARCH 8(2):85-95 Nagase T; Nakayama M; Nakajima D; Kikuno R; Ohara O Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro	24	2
265	3	184 2001 DNA RESEARCH 8(4):179-187 Nagase T; Kikuno R; Ohara O Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins	5	2
266	4	185 2001 DNA RESEARCH 8(6):319-327 Nagase T; Kikuno R; Ohara O Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins	4	2
267	1	195 2001 DRUG DISCOVERY TODAY 6(13):681-688 Southan C A genomic perspective on human proteases as drug targets	11	2
268	2	200 2001 DRUG DISCOVERY TODAY 6(19):996-1004 Maggio ET; Ramnarayan K Recent developments in computational proteomics	6	2
269	1	204 2001 EMBO JOURNAL 20(17):4704-4716 Tutt A; Bertwistle D; Valentine J; Gabriel A; Swift S; Ross G; Griffin C; Thacker J; Ashworth A Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences	30	2
270	1	211 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(24):6435-6448 Titeux M; Brocheriou V; Xue ZG; Gao J; Pellissier JF; Guicheney P; Paulin D; Li ZL Human synemin gene generates splice variants encoding two distinct intermediate filament proteins	7	2
271	3	224 2001 EXPERT OPINION ON INVESTIGATIONAL DRUGS 10(7):1327-1344 Sawyer T; Boyce B; Dalgarno D; Iuliucci J Src inhibitors: genomics to therapeutics	7	2
272	1	240 2001 GENE 273(1):51-61 Kurdyukov SG; Lebedev YB; Artamonova II; Gorodentseva TN; Batrak AV; Mamedov IZ; Azhikina TL; Legchilina SP; Efimenko IG; Gardiner K; Sverdlov ED Full-sized HERV-K (HML-2) human endogenous retroviral LTR sequences on human chromosome 21: map locations and evolutionary history	6	2
273	2	250 2001 GENE 277(1-2):31-47 Goldstrohm AC; Greenleaf AL; Garcia-Blanco MA Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing	16	2
274	1	263 2001 GENETICS 158(3):949-957 Rubin E; Lithwick G; Levy AA Structure and evolution of the hAT transposon superfamily	5	2
275	1	270 2001 GENETICS 159(3):1191-1199 Urrutia AO; Hurst LD Codon usage bias covaries with expression breadth and the rate of synonymous evolution in humans, but this is not evidence for selection	9	2
276	1	273 2001 GENOME RESEARCH 11(4):540-546 Gentles AJ; Karlin S Genome-scale compositional comparisons in eukaryotes	12	2
277	2	283 2001 GENOME RESEARCH 11(7):1156-1166 Dean M; Rzhetsky A; Allikmets R The human ATP-binding cassette (ABC) transporter superfamily	69	2
278	2	286 2001 GENOME RESEARCH 11(8):1353-1364 Caceres M; Puig M; Ruiz A Molecular characterization of two natural hotspots in the Drosophila buzzatii genome induced by transposon insertions	7	2
279	2	290 2001 GENOME RESEARCH 11(9):1520-1526 Beaudoing E; Gautheret D Identification of alternate polyadenylation sites and analysis of their tissue distribution using EST data	7	2
280	5	295 2001 GENOME RESEARCH 11(10):1736-1745 Zhao SY; Shatsman S; Ayodeji B; Geer K; Tsegaye G; Krol M; Gebregeorgis E; Shvartsbeyn A; Russell D; Overton L; Jiang LX; Dimitrov G; Tran K; Shetty J; Malek JA; Feldblyum T; Nierman WC; Fraser CM Mouse BAC ends quality assessment and sequence analyses	10	2
281	1	302 2001 GENOME RESEARCH 11(11):1854-1860 Ponger L; Duret L; Mouchiroud D Determinants of CpG islands: Expression in early embryo and isochore structure	10	2
282	1	308 2001 GENOME RESEARCH 11(12):1996-2008 Ponting CP; Mott R; Bork P; Copley RR Novel protein domains and repeats in Drosophila melanogaster: Insights into structure, function, and evolution	3	2
283	1	328 2001 HUMAN MOLECULAR GENETICS 10(13):1379-1386 Sakai K; Shirasawa S; Ishikawa N; Ito K; Tamai H; Kuma K; Akamizu T; Tanimura M; Furugaki K; Yamamoto K; Sasazuki T Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q133 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese	14	2
284	2	333 2001 HUMAN MOLECULAR GENETICS 10(21):2319-2328 Miller MP; Kumar S Understanding human disease mutations through the use of interspecific genetic variation	12	2
285	1	334 2001 HUMAN MOLECULAR GENETICS 10(23):2661-2669 Kondrashov FA; Koonin EV Origin of alternative splicing by tandem exon duplication	5	2
286	4	358 2001 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 286(18):2322-2324 Collins FS; Guttmacher AE Genetics moves into the medical mainstream	8	2
287	2	379 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(47):43604-43610 Wang LQ; Wu Q; Qiu P; Mirza A; McGuirk M; Kirschmeier P; Greene JR; Wang YL; Pickett CB; Liu SX Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches	21	2
288	1	385 2001 JOURNAL OF CELL BIOLOGY 154(1):123-136 Young P; Ehler E; Gautel M Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly	20	2
289	1	387 2001 JOURNAL OF CELL SCIENCE 114(14):2569-2575 Hesse M; Magin TM; Weber K Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18	33	2
290	2	391 2001 JOURNAL OF CELLULAR PHYSIOLOGY 188(2):143-160 Black AR; Black JD; Azizkhan-Clifford J Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer	53	2
291	1	392 2001 JOURNAL OF CELLULAR PHYSIOLOGY 188(2):161-169 Cillo C; Cantile M; Faiella A; Boncinelli E Homeobox genes in normal and malignant cells	14	2
292	2	406 2001 JOURNAL OF MOLECULAR ENDOCRINOLOGY 27(2):123-131 Akker SA; Smith PJ; Chew SL Nuclear post-transcriptional control of gene expression	8	2
293	1	416 2001 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 299(1):268-276 Weiner DM; Burstein ES; Nash N; Croston GE; Currier EA; Vanover KE; Harvey SC; Donohue E; Hansen HC; Andersson CM; Spalding TA; Gibson DFC; Krebs-Thomson K; Powell SB; Geyer MA; Hacksell U; Brann MR 5-hydroxytryptamine(2A) receptor inverse agonists as antipsychotics	15	2
294	1	427 2001 JOURNAL OF VIROLOGY 75(19):8917-8926 Reus K; Mayer J; Sauter M; Zischler H; Muller-Lantzsch N; Meese E HERV-K(OLD): Ancestor sequences of the human endogenous retrovirus family HERV-K(HML-2)	3	2
295	2	432 2001 M S-MEDECINE SCIENCES 17(3):299-308 Heilig R; Bruls T Initial view of the human genomic sequence	3	2
296	3	436 2001 MAMMALIAN GENOME 12(8):575-581 Moldin SO; Farmer ME; Chin HR; Battey JF Trans-NIH neuroscience initiatives on mouse phenotyping and mutagenesis	8	2
297	2	437 2001 MAMMALIAN GENOME 12(9):673-677 Kondo S; Shinagawa A; Saito T; Kiyosawa H; Yamanaka I; Aizawa K; Fukuda S; Hara A; Itoh M; Kawai J; Shibata K; Hayashizaki Y Computational analysis of full-length mouse cDNAs compared with human genome sequences	5	2
298	1	449 2001 MOLECULAR AND CELLULAR NEUROSCIENCE 18(1):80-90 Hartmann AM; Rujescu D; Giannakouros T; Nikolakaki E; Goedert M; Mandelkow EM; Gao QS; Andreadis A; Stamm S Regulation of alternative splicing of human tau exon 10 by phosphorylation of splicing factors	7	2
299	4	454 2001 MOLECULAR BIOLOGY AND EVOLUTION 18(9):1694-1702 Wuchty S Scale-free behavior in protein domain networks	15	2
300	1	457 2001 MOLECULAR BIOLOGY AND EVOLUTION 18(12):2186-2194 Boissinot SP; Furano AV Adaptive evolution in LINE-1 retrotransposons	4	2

#	Cited nodes	Nodes / Authors	GCS	LCS
301	2	463 2001 MOLECULAR GENETICS AND METABOLISM 74(1-2):51-63 Vladutiu GD Heterozygosity: An expanding role in proteomics	4	2
302	1	498 2001 NATURE BIOTECHNOLOGY 19(3):207-209 Bailey D; Zanders E; Dean P The end of the beginning for genomic medicine	4	2
303	1	504 2001 NATURE GENETICS 27(3):232-234 Burge CB Chipping away at the transcriptome	6	2
304	3	540 2001 NATURE REVIEWS GENETICS 2(10):801-809 Brenner SE A tour of structural genomics	18	2
305	2	544 2001 NATURE REVIEWS MOLECULAR CELL BIOLOGY 2(7):493-503 Kinoshita K; Honjo T Linking class-switch recombination with somatic hypermutation	32	2
306	2	550 2001 NEOPLASIA 3(4):314-323 Dai ZY; Lakshmanan RR; Zhu WG; Smiraglia DJ; Rush LJ; Fruhwald MC; Brena RM; Li B; Wright FA; Ross P; Otterson GA; Plass C Global methylation profiling of lung cancer identifies novel methylated genes	16	2
307	2	563 2001 NUCLEIC ACIDS RESEARCH 29(18):3864-3872 Shchepinov MS; Denissenko MF; Smylie KJ; Worl RJ; Leppin AL; Cantor CR; Rodi CP Matrix-induced fragmentation of P3 '-N5 ' phosphoramidate- containing DNA: high-throughput MALDI-TOF analysis of genomic sequence polymorphisms	10	2
308	1	564 2001 NUCLEIC ACIDS RESEARCH 29(19):4006-4013 Levine A; Durbin R A computational scan for U12-dependent introns in the human genome sequence	5	2
309	1	567 2001 NUCLEIC ACIDS RESEARCH 29(21):4493-4501 Yu F; Zingler N; Schumann G; Stratling WH Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription	4	2
310	2	596 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(17):9748-9753 Pevzner PA; Tang HX; Waterman MS An Eulerian path approach to DNA fragment assembly	8	2
311	1	641 2001 SCIENCE 293(5532):1048-1048 Salzberg SL; Eisen JA Lateral gene transfer or viral colonization? Response	2	2
312	1	642 2001 SCIENCE 293(5532):1070-1074 Martienssen RA; Colot V DNA methylation and epigenetic inheritance in plants and filamentous fungi	43	2
313	2	646 2001 SCIENCE 294(5547):1669-1670 Kwok PY Genomics - Genetic association by whole-genome analysis?	7	2
314	3	647 2001 SCIENTIST 15(20):1-+ Hollon T Human genes: How many?	0	2
315	2	650 2001 SCIENTIST 15(4):16-16 Russo E Negotiating the human genome	0	2
316	2	670 2001 TRENDS IN BIOTECHNOLOGY 19(10):S17-S22 Choudhary JS; Blackstock WP; Creasy DM; Cottrell JS Matching peptide mass spectra to EST and genomic DNA databases	7	2
317	2	673 2001 TRENDS IN BIOTECHNOLOGY 19(10):S67-S71 Jhoti H High-throughput structural proteomics using x-rays	9	2
318	3	678 2001 TRENDS IN BIOTECHNOLOGY 19(12):511-518 Ko MSH Embryogenomics: developmental biology meets genomics	7	2
319	2	679 2001 TRENDS IN BIOTECHNOLOGY 19(12):519-523 Nebert DW; Bingham E Pharmacogenomics: out of the lab and into the community	7	2
320	1	686 2001 TRENDS IN GENETICS 17(5):235-237 Ponting CP Plagiarized bacterial genes in the human book of life	3	2
321	1	704 2001 TRENDS IN MICROBIOLOGY 9(7):302-307 Pallen MJ; Lam AC; Loman NJ; McBride A An abundance of bacterial ADP-ribosyltransferases - implications for the origin of exotoxins and their human homologues	6	2
322	2	713 2001 TRENDS IN MOLECULAR MEDICINE 7(11):521-526 Blackwell JM Genetics and genomics in infectious disease susceptibility	9	2
323	2	719 2001 TRENDS IN PLANT SCIENCE 6(5):195-196 Messing J Do plants have more genes than humans?	4	2
324	1	723 2001 VIROLOGY 290(1):83-90 Vinogradova TV; Leppik LP; Nikolaev LG; Akopov SB; Kleiman AM; Senyuta NB; Sverdlov ED Solitary human endogenous retroviruses-K LTRs retain transcriptional activity in vivo, the mode of which is different in different cell types	2	2
325	5	741 2002 AMERICAN JOURNAL OF HUMAN GENETICS 70(1):101-107 DeWan AT; Parrado AR; Matise TC; Leal SM The map problem: A comparison of genetic and sequence-based physical maps	4	2
326	2	743 2002 AMERICAN JOURNAL OF HUMAN GENETICS 70(2):425-434 Schaid DJ; Rowland CM; Tines DE; Jacobson RM; Poland GA Score tests for association between traits and haplotypes when linkage phase is ambiguous	17	2
327	7	787 2002 ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE 31():45-71 Ponting CP; Russell RR The natural history of protein domains	5	2
328	2	810 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 290(3):1079-1083 Xu HM; Zhang S; Liu DP; Li XG; Hao DL; Liang CC Efficient isolation of regulatory sequences from human genome and BAC DNA	2	2
329	4	885 2002 BRITISH MEDICAL JOURNAL 324(7344):1018-1022 Bayat A Science, medicine, and the future - Bioinformatics	4	2
330	2	886 2002 BRITISH MEDICAL JOURNAL 324(7351):1438-1442 Elliott R; Ong TJ Science, medicine, and the future - Nutritional genomics	6	2
331	3	907 2002 CELL 109(3):307-320 Panda S; Antoch MP; Miller BH; Su AI; Schook AB; Straume M; Schultz PG; Kay SA; Takahashi JS; Hogenesch JB Coordinated transcription of key pathways in the mouse by the circadian clock	49	2
332	4	956 2002 CURRENT OPINION IN BIOTECHNOLOGY 13(1):68-71 Goodman N Biological data becomes computer literate: new advances in bioinformatics	9	2
333	7	958 2002 CURRENT OPINION IN CELL BIOLOGY 14(3):343-350 Weiner AM SINEs and LINEs: the art of biting the hand that feeds you	5	2
334	7	960 2002 CURRENT OPINION IN CHEMICAL BIOLOGY 6(1):13-16 Camargo AA; de Souza SJ; Brentani RR; Simpson AJG Human gene discovery through experimental definition of transcribed regions of the human genome	2	2
335	2	986 2002 CURRENT OPINION IN PHARMACOLOGY 2(4):361-365 Weinstein JN 'Omic' and hypothesis-driven research in the molecular pharmacology of cancer	4	2
336	2	990 2002 CURRENT OPINION IN STRUCTURAL BIOLOGY 12(1):61-68 Lim WA The modular logic of signaling proteins: building allosteric switches from simple binding domains	6	2
337	5	1022 2002 DNA RESEARCH 9(3):99-106 Nakajima D; Okazaki N; Yamakawa H; Kikuno R; Ohara O; Nagase T Construction of expression-ready cDNA clones for KIAA genes: Manual curation of 330 KIAA cDNA clones	3	2
338	5	1051 2002 EMBO JOURNAL 21(21):5899-5910 Cost GJ; Feng QH; Jacquier A; Boeke JD Human L1 element target-primed reverse transcription in vitro	2	2
339	6	1116 2002 GENE 294(1-2):35-44 Gilligan P; Brenner S; Venkatesh B Fugu and human sequence comparison identifies novel human genes and conserved non-coding sequences	3	2
340	7	1126 2002 GENE 300(1-2):117-127 Oliver JL; Carpena P; Roman-Roldan R; Mata-Balaguer T; Mejias-Romero A; Hackenberg M; Bernaola-Galvan P Isochore chromosome maps of the human genome	2	2
341	3	1147 2002 GENETICA 115(1):65-80 Betran E; Long MY Expansion of genome coding regions by acquisition of new genes	3	2
342	1	1170 2002 GENOME RESEARCH 12(1):47-56 Doerks T; Copley RR; Schultz J; Ponting CP; Bork P Systematic identification of novel protein domain families associated with nuclear functions	7	2
343	3	1173 2002 GENOME RESEARCH 12(1):81-87 Lane RP; Roach JC; Lee IY; Boysen C; Smit A; Trask BJ; Hood L Genomic analysis of the olfactory receptor region of the mouse and human T-cell receptor alpha/delta loci	3	2
344	2	1175 2002 GENOME RESEARCH 12(1):198-202 Nekrutenko A; Makova KD; Li WH The K-A/K-S ratio test for assessing the protein-coding potential of genomic regions: An empirical and simulation study	9	2
345	1	1179 2002 GENOME RESEARCH 12(3):379-390 Yoshihama M; Uechi T; Asakawa S; Kawasaki K; Kato S; Higa S; Maeda N; Minoshima S; Tanaka T; Shimizu N; Kenmochi N The human ribosomal protein genes: Sequencing and comparative analysis of 73 genes	7	2
346	5	1186 2002 GENOME RESEARCH 12(5):713-728 Bi WM; Yan J; Stankiewicz P; Park SS; Walz K; Boerkoel CF; Potocki L; Shaffer LG; Devriendt K; Nowaczyk MJM; Inoue K; Lupski JR Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse	8	2
347	4	1191 2002 GENOME RESEARCH 12(6):894-908 Chureau C; Prissette M; Bourdet A; Barbe V; Cattolico L; Jones L; Eggen A; Avner P; Duret L Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine	7	2
348	8	1202 2002 GENOME RESEARCH 12(8):1277-1285 Thomas JW; Prasad AB; Summers TJ; Lee-Lin SQ; Maduro VVB; Idol JR; Ryan JF; Thomas PJ; McDowell JC; Green ED Parallel construction of orthologous sequence-ready clone contig maps in multiple species	3	2
349	6	1216 2002 GENOME RESEARCH 12(12):1827-1836 Majewski J; Ott J Distribution and characterization of regulatory elements in the human genome	3	2
350	5	1217 2002 GENOME RESEARCH 12(12):1837-1845 Kan ZY; States D; Gish W Selecting for functional alternative splices in ESTs	3	2
351	2	1224 2002 GENOMICS 79(2):154-161 Kurihara LJ; Semenova E; Miller W; Ingram RS; Guan XJ; Tilghman SM Candidate genes required for embryonic development: A comparative analysis of distal mouse chromosome 14 and human chromosome 13q22	3	2
352	1	1227 2002 GENOMICS 79(2):225-240 Deussing J; Kouadio M; Rehman S; Werber I; Schwinde A; Peters C Identification and characterization of a dense cluster of placenta-specific cysteine peptidase genes and related genes on mouse chromosome 13	5	2
353	2	1232 2002 GENOMICS 79(4):464-470 Wain HM; Bruford EA; Lovering RC; Lush MJ; Wright MW; Povey S Guidelines for human gene nomenclature	15	2
354	1	1235 2002 GENOMICS 79(5):628-634 Nigumann P; Redik K; Matlik K; Speek M Many human genes are transcribed from the antisense promoter of L1 retrotransposon	4	2
355	7	1236 2002 GENOMICS 79(5):635-656 Christian SL; McDonough J; Liu CY; Shaikh S; Vlamakis V; Badner JA; Chakravarti A; Gershon ES An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia	6	2
356	5	1241 2002 GENOMICS 79(6):824-832 Reymond A; Camargo AA; Deutsch S; Stevenson BJ; Parmigiani RB; Ucla C; Bettoni F; Rossier C; Lyle R; Guipponi M; de Souza S; Iseli C; Jongeneel CV; Bucher P; Simpson AJG; Antonarakis SE Nineteen additional unpredicted transcripts from human chromosome 21	5	2
357	6	1246 2002 GENOMICS 80(2):138-139 Li SY; Liao JY; Cutler G; Hoey T; Hogenesch JB; Cooke MP; Schultz PG; Ling XFB Comparative analysis of human genome assemblies reveals genome- level differences	2	2
358	4	1248 2002 GENOMICS 80(2):213-222 Anisimov SV; Tarasov KV; Stern MD; Lakatta EG; Boheler KR A quantitative and validated SAGE transcriptome reference for adult mouse heart	4	2
359	8	1252 2002 GENOMICS 80(3):326-330 Xie HQ; Zhu W; Wasserman A; Grebinskiy V; Olson A; Mintz L Computational analysis of alternative splicing using EST tissue information	4	2
360	2	1275 2002 HUMAN MOLECULAR GENETICS 11(13):1561-1567 Letunic I; Copley RR; Bork P Common exon duplication in animals and its role in alternative splicing	2	2
361	4	1284 2002 HUMAN MUTATION 20(1):57-64 Werner M; Sych M; Herbon N; Illig T; Konig IR; Wjst M Large-scale determination of SNP allele frequencies in DNA pools using MALDI-TOF mass spectrometry	11	2
362	2	1325 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(7):5448-5452 Stone JR; Maki JL; Blacklow SC; Collins T The SCAN domain of ZNF174 is a dimer	2	2
363	2	1369 2002 JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY 55(1):1-18 Bowen DJ Haemophilia a and haemophilia b: molecular insights	1	2
364	1	1390 2002 JOURNAL OF MEDICINAL CHEMISTRY 45(6):1151-1175 McCluskey A; Sim ATR; Sakoff JA Serine-threonine protein phosphatase inhibitors: Development of potential therapeutic strategies	12	2
365	2	1396 2002 JOURNAL OF MOLECULAR BIOLOGY 315(5):1063-1073 Liu B; Huang L; Sihlbom C; Burlingame A; Marks JD Towards proteome-wide production of monoclonal antibody by phage display	12	2
366	4	1407 2002 JOURNAL OF MOLECULAR ENDOCRINOLOGY 28(1):1-17 McCarthy MI Susceptibility gene discovery for common metabolic and endocrine traits	5	2
367	4	1419 2002 JOURNAL OF NEUROSCIENCE 22(14):5889-5899 Daoud R; Mies G; Smialowska A; Olah L; Hossmann KA; Stamm S Ischemia induces a translocation of the splicing factor tra2- beta 1 and changes alternative splicing patterns in the brain	3	2
368	2	1473 2002 MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS 66(1):39-+ Graves PR; Haystead TAJ Molecular biologist's guide to proteomics	15	2
369	3	1494 2002 MOLECULAR BIOLOGY AND EVOLUTION 19(3):336-340 Payseur BA; Nachman MW Gene density and human nucleotide polymorphism	4	2
370	2	1498 2002 MOLECULAR BIOLOGY AND EVOLUTION 19(5):654-663 Betran E; Wang W; Jin L; Long MY Evolution of the Phosphoglycerate mutase processed gene in human and chimpanzee revealing the origin of a new primate gene	4	2
371	2	1499 2002 MOLECULAR BIOLOGY AND EVOLUTION 19(6):926-937 Bartolome C; Maside X; Charlesworth B On the abundance and distribution of transposable elements in the genome of Drosophila melanogaster	11	2
372	4	1502 2002 MOLECULAR BIOLOGY AND EVOLUTION 19(7):1181-1197 Birdsell JA Integrating genomics, bioinformatics, and classical genetics to study the effects of recombination on genome evolution	9	2
373	4	1543 2002 NATURE 415(6872):702-709 Hoffman SL; Subramanian GM; Collins FH; Venter JC Plasmodium, human and Anopheles genomics and malaria	28	2
374	1	1548 2002 NATURE 417(6887):447-452 Enomoto A; Kimura H; Chairoungdua A; Shigeta Y; Jutabha P; Cha SH; Hosoyamada M; Takeda M; Sekine T; Igarashi T; Matsuo H; Kikuchi Y; Oda T; Ichida K; Hosoya T; Shimokata K; Niwa T; Kanai Y; Endou H Molecular identification of a renal urate-anion exchanger that regulates blood urate levels	13	2
375	3	1552 2002 NATURE 418(6893):79-85 Glockner G; Eichinger L; Szafranski K; Pachebat JA; Bankier AT; Dear PH; Lehmann D; Baumgart C; Parra G; Abril JF; Guigo R; Kumpf K; Tunggal B; Cox E; Quail MA; Platzer M; Rosenthal A; Noegel AA; Dictyostelium Genome Sequencing Sequence and analysis of chromosome 2 of Dictyostelium discoideum	20	2
376	1	1581 2002 NATURE GENETICS 31(2):180-183 Lercher MJ; Urrutia AO; Hurst LD Clustering of housekeeping genes provides a unified model of gene order in the human genome	26	2
377	1	1627 2002 NUCLEIC ACIDS RESEARCH 30(1):27-30 Tateno Y; Imanishi T; Miyazaki S; Fukami-Kobayashi K; Saitou N; Sugawara H; Gojobori T DNA Data Bank of Japan (DDBJ) for genome scale research in life science	11	2
378	2	1632 2002 NUCLEIC ACIDS RESEARCH 30(1):205-206 Paces J; Pavlicek A; Paces V HERVd: database of human endogenous retroviruses	4	2
379	3	1642 2002 NUCLEIC ACIDS RESEARCH 30(7):1427-1464 Anantharaman V; Koonin EV; Aravind L Comparative genomics and evolution of proteins involved in RNA metabolism	22	2
380	2	1643 2002 NUCLEIC ACIDS RESEARCH 30(7):1575-1584 Enright AJ; Van Dongen S; Ouzounis CA An efficient algorithm for large-scale detection of protein families	10	2
381	4	1644 2002 NUCLEIC ACIDS RESEARCH 30(8):1751-1756 Castresana J Genes on human chromosome 19 show extreme divergence from the mouse orthologs and a high GC content	5	2
382	3	1679 2002 PHARMACOLOGY & THERAPEUTICS 93(2-3):79-98 Fabbro D; Ruetz S; Buchdunger E; Cowan-Jacob SW; Fendrich G; Liebetanz J; Mestan J; O'Reilly T; Traxler P; Chaudhuri B; Fretz H; Zimmermann J; Meyer T; Caravatti G; Furet P; Manley PW Protein kinases as targets for anticancer agents: from inhibitors to useful drugs	7	2
383	2	1687 2002 PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES 357(1420):531-544 Furlong RF; Holland PWH Were vertebrates octoploid?	9	2
384	2	1710 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(1):309-314 Ding YC; Chi HC; Grady DL; Morishima A; Kidd JR; Kidd KK; Flodman P; Spence MA; Schuck S; Swanson JM; Zhang YP; Moyzis RK Evidence of positive selection acting at the human dopamine receptor D4 gene locus	10	2
385	1	1712 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(2):574-579 Paegel BM; Emrich CA; Weyemayer GJ; Scherer JR; Mathies RA High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor	19	2
386	3	1723 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(7):4143-4144 Green P Whole-genome disassembly	2	2
387	2	1728 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(9):6152-6156 Nam DK; Lee S; Zhou GL; Cao XH; Wang C; Clark T; Chen JJ; Rowley JD; Wang SM Oligo(dT) primer generates a high frequency of truncated cDNAs through internal poly(A) priming during reverse transcription	7	2
388	2	1729 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(10):6802-6805 Harafuji N; Keys DN; Levine M Genome-wide identification of tissue-specific enhancers in the Ciona tadpole	7	2
389	1	1731 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(13):8748-8753 Webster MT; Smith NGC; Ellegren H Microsatellite evolution inferred from human-chimpanzee genomic sequence alignments	6	2
390	3	1742 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(21):13675-13680 Chumakov I; Blumenfeld M; Guerassimenko O; Cavarec L; Palicio M; Abderrahim H; Bougueleret L; Barry C; Tanaka H; La Rosa P; Puech A; Tahri N; Cohen-Akenine A; Delabrosse S; Lissarrague S; Picard FP; Maurice K; Essioux L; Millasseau P; Grel P; Debailleul V; Simon AM; Caterina D; Dufaure I; Malekzadeh K; Belova M; Luan JJ; Bouillot M; Sambucy JL; Primas G; Saumier M; Boubkiri N; Martin-Saumier S; Nasroune M; Peixoto H; Delaye A; Pinchot V; Bastucci M; Guillou S; Chevillon M; Sainz-Fuertes R; Meguenni S; Aurich-Costa J; Cherif D; Gimalac A; Van Duijn C; Gauvreau D; Quelette G; Fortier I; Realson J; Sherbatich T; Riazanskaia N; Rogaev E; Raeymaekers P; Aerssens J; Konings F; Luyten W; Macciardi F; Sham PC; Straub RE; Weinberger DR; Cohen N; Cohen D Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia	18	2
391	5	1796 2002 SCIENCE 298(5600):1912-+ Manning G; Whyte DB; Martinez R; Hunter T; Sudarsanam S The protein kinase complement of the human genome	28	2
392	3	1828 2002 TRENDS IN BIOTECHNOLOGY 20(2):79-84 Norin M; Sundstrom M Structural proteomics: developments in structure-to-function predictions	6	2
393	3	1829 2002 TRENDS IN BIOTECHNOLOGY 20(3):110-115 Croston GE Functional cell-based uHTS in chemical genomic drug discovery	6	2
394	2	1836 2002 TRENDS IN GENETICS 18(1):53-55 Coward E; Haas SA; Vingron M SpliceNest: visualizing gene structure and alternative splicing based on EST clusters	7	2
395	3	1843 2002 TRENDS IN GENETICS 18(10):529-536 Edwards AM; Kus B; Jansen R; Greenbaum D; Greenblatt J; Gerstein M Bridging structural biology and genomics: assessing protein interaction data with known complexes	6	2
396	3	1846 2002 TRENDS IN MICROBIOLOGY 10(1):1-4 Lawrence JG; Ochman H Reconciling the many faces of lateral gene transfer	14	2
397	2	1849 2002 TRENDS IN PHARMACOLOGICAL SCIENCES 23(3):140-146 Lu ZL; Saldanha JW; Hulme EC Seven-transmembrane receptors: crystals clarify	21	2
398	11	2016 2003 GENOME RESEARCH 13(1):13-26 Hardison RC; Roskin KM; Yang S; Diekhans M; Kent WJ; Weber R; Elnitski L; Li J; O'Connor M; Kolbe D; Schwartz S; Furey TS; Whelan S; Goldman N; Smit A; Miller W; Chiaromonte F; Haussler D Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution	5	2
399	11	2017 2003 GENOME RESEARCH 13(1):27-36 Collins JE; Goward ME; Cole CG; Smink LJ; Huckle EJ; Knowles S; Bye JM; Beare DM; Dunham I Reevaluating human gene annotation: A second-generation analysis of chromosome 22	4	2
400	4	2213 2003 NATURE 421(6920):231-237 Kamath RS; Fraser AG; Dong Y; Poulin G; Durbin R; Gotta M; Kanapin A; Le Bot N; Moreno S; Sohrmann M; Welchman DP; Zipperlen P; Ahringer J Systematic functional analysis of the Caenorhabditis elegans genome using RNAi	21	2

#	Cited nodes	Nodes / Authors	GCS	LCS
401	8	2223 2003 NATURE 423(6942):825-U2 Skaletsky H; Kuroda-Kawaguchi T; Minx PJ; Cordum HS; Hillier L; Brown LG; Repping S; Pyntikova T; Ali J; Bieri T; Chinwalla A; Delehaunty A; Delehaunty K; Du H; Fewell G; Fulton L; Fulton R; Graves T; Hou SF; Latrielle P; Leonard S; Mardis E; Maupin R; McPherson J; Miner T; Nash W; Nguyen C; Ozersky P; Pepin K; Rock S; Rohlfing T; Scott K; Schultz B; Strong C; Tin-Wollam A; Yang SP; Waterston RH; Wilson RK; Rozen S; Page DC The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes	4	2
402	4	2224 2003 NATURE 423(6942):873-876 Rozen S; Skaletsky H; Marszalek JD; Minx PJ; Cordum HS; Waterston RH; Wilson RK; Page DC Abundant gene conversion between arms of palindromes in human and ape Y chromosomes	4	2
403	2	2243 2003 NATURE REVIEWS DRUG DISCOVERY 2(1):63-69 Knowles J; Gromo G Target selection in drug discovery	3	2
404	8	2245 2003 NATURE REVIEWS GENETICS 4(1):20-28 Olson MV; Varki A Sequencing the chimpanzee genome: Insights into human evolution and disease	6	2
405	2	2255 2003 NATURE STRUCTURAL BIOLOGY 10(1):33-37 Hui JY; Stangl K; Lane WS; Bindereif A HnRNP L stimulates splicing of the eNOS gene by binding to variable-length CA repeats	3	2
406	4	2267 2003 NUCLEIC ACIDS RESEARCH 31(1):51-54 Karolchik D; Baertsch R; Diekhans M; Furey TS; Hinrichs A; Lu YT; Roskin KM; Schwartz M; Sugnet CW; Thomas DJ; Weber RJ; Haussler D; Kent WJ The UCSC Genome Browser Database	4	2
407	9	2314 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(6):3022-3024 Waterston RH; Lander ES; Sulston JE More on the sequencing of the human genome	2	2
408	1	6 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(1):25-34 Ahmed ZM; Riazuddin S; Bernstein SL; Ahmed Z; Khan S; Griffith AJ; Morell RJ; Friedman TB; Riazuddin S; Wilcox ER Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F	34	1
409	2	16 2001 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 281(5):C1587-C1595 Zhao BT; Bowden RA; Stavchansky SA; Bowman PD Human endothelial cell response to gram-negative lipopolysaccharide assessed with cDNA microarrays	12	1
410	1	18 2001 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 281(5):F781-F794 Gamba G Alternative splicing and diversity of renal transporters	5	1
411	2	23 2001 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 40(18):3341-+ Wess G; Urmann M; Sickenberger B Medicinal chemistry: Challenges and opportunities	15	1
412	2	33 2001 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 2():259-269 Tang CM; Moxon ER The impact of microbial genomics on antimicrobial drug development	3	1
413	2	49 2001 BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM 15(3):293-308 Gloyn AL; McCarthy MI The genetics of type 2 diabetes	3	1
414	1	50 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 282(2):499-506 Lieberman AP; Friedlich DL; Harmison G; Howell BW; Jordan CL; Breedlove SM; Fischbeck KH Androgens regulate the mammalian homologues of invertebrate sex determination genes tra-2 and fox-1	2	1
415	1	52 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 285(5):1150-1154 Koenig U; Eckhart L; Tschachler E Evidence that caspase-13 is not a human but a bovine gene	3	1
416	1	54 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286(5):863-868 Asakawa S; Tsunematsu K; Takayanagi A; Sasaki T; Shimizu A; Shintani A; Kawasaki K; Mungall AJ; Beck S; Minoshima S; Shimizu N The genomic structure and promoter region of the human Parkin gene	6	1
417	3	64 2001 BIOESSAYS 23(6):473-476 Nal B; Mohr E; Ferrier P Location analysis of DNA-bound proteins at the whole-genome level: untangling transcriptional regulatory networks	5	1
418	4	69 2001 BIOINFORMATICS 17(7):581-586 Ke XY; Tapper W; Collins A LDB2000: sequence-based integrated maps of the human genome	2	1
419	2	76 2001 BIOPOLYMERS 60(3):220-228 Ting AY; Witte K; Shah K; Kraybill B; Shokat KM; Schultz PG Phage-display evolution of tyrosine kinases with altered nucleotide specificity	2	1
420	2	78 2001 BIOTECHNIQUES 30(3):626-+ Sawyer TK Cancer - Emerging breakthrough drugs	3	1
421	1	83 2001 BJU INTERNATIONAL 88():11-17 Masuho Y; Matsumoto S; Isogai T; Nagai K; Nagahari K The search for drug target molecules from genomics	1	1
422	2	94 2001 CANCER RESEARCH 61(18):6640-6648 Bullrich F; Fujii H; Calin G; Mabuchi H; Negrini M; Pekarsky Y; Rassenti L; Alder H; Reed JC; Keating MJ; Kipps TJ; Croce CM Characterization of the 13q14 tumor suppressor locus in CLL: Identification of ALT1, an alternative splice variant of the LEU2 gene	7	1
423	1	99 2001 CELL 106(2):171-182 Derkatch IL; Bradley ME; Hong JY; Liebman SW Prions affect the appearance of other prions: The story of [PIN+]	22	1
424	2	105 2001 CELL 107(2):195-207 Billuart P; Winter CG; Maresh A; Zhao XS; Luo LQ Regulating axon branch stability: The role of p190 RhoGAP in repressing a retraction signaling pathway	33	1
425	2	108 2001 CELLULAR AND MOLECULAR LIFE SCIENCES 58(7):868-884 Jonsson AP Mass spectrometry for protein and peptide characterisation	12	1
426	1	112 2001 CHEMICAL REVIEWS 101(8):2313-2340 Jackson MD; Denu JM Molecular reactions of protein phosphatases - Insights from structure and chemistry	14	1
427	1	117 2001 CHROMOSOMA 110(3):148-158 Pinsker W; Haring E; Hagemann S; Miller WJ The evolutionary life history of P transposons: from horizontal invaders to domesticated neogenes	3	1
428	2	134 2001 CURRENT BIOLOGY 11(5):R155-R158 Koonin EV Computational genomics	2	1
429	8	139 2001 CURRENT BIOLOGY 11(20):R808-R811 Scherer SW; Cheung J Discovery of the human genome sequence in the public and private databases	1	1
430	1	141 2001 CURRENT BIOLOGY 11(19):1503-1511 Watters JW; Dewar K; Lehoczky J; Boyartchuk V; Dietrich WF Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor	22	1
431	2	143 2001 CURRENT GENETICS 40(3):157-171 Bill RM Yeast - a panacea for the structure-function analysis of membrane proteins?	5	1
432	3	147 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(4):340-347 Pelletier J; Sidhu S Mapping protein-protein interactions with combinatorial biology methods	4	1
433	3	151 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):607-612 Griffin TJ; Goodlett DR; Aebersold R Advances in proteome analysis by mass spectrometry	8	1
434	4	152 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):622-625 Dean NM Functional genomics and target validation approaches using antisense oligonucleotide technology	14	1
435	2	156 2001 CURRENT OPINION IN CELL BIOLOGY 13(5):611-618 Brummendorf T; Lemmon V Immunoglobulin superfamily receptors: cis-interactions, intracellular adapters and alternative splicing regulate adhesion	8	1
436	2	168 2001 CURRENT OPINION IN HEMATOLOGY 8(4):252-261 Golub TR Genomic approaches to the pathogenesis of hematologic malignancy	1	1
437	1	180 2001 DISEASE MARKERS 17(2):67-75 Caballero OL; de Souza SJ; Brentani RR; Simpson AJG Alternative spliced transcripts as cancer markers	5	1
438	2	191 2001 DRUG DISCOVERY TODAY 6(8):398-399 Szymkowski DE Too many targets, not enough target validation	1	1
439	1	196 2001 DRUG DISCOVERY TODAY 6(15):766-768 Gurwitz D; Weizman A Animal models and human genome diversity: the pitfalls of inbred mice	4	1
440	2	203 2001 ELECTROPHORESIS 22(19):4104-4117 Mitnik L; Novotny M; Felten C; Buonocore S; Koutny L; Schmalzing D Recent advances in DNA sequencing by capillary and microdevice electrophoresis	6	1
441	2	207 2001 EMBO REPORTS 2(7):586-592 Cuadrado M; Sacristan M; Antequera F Species-specific organization of CpG island promoters at mammalian homologous genes	4	1
442	2	226 2001 EXPERT OPINION ON THERAPEUTIC PATENTS 11(11):1729-1752 Ilies MA; Balaban AT Recent developments in cationic lipid-mediated gene delivery and gene therapy	5	1
443	2	230 2001 FEBS LETTERS 498(2-3):214-218 Southan C A genomic perspective on human proteases	10	1
444	2	235 2001 FEBS LETTERS 508(1):143-148 Baranova AV; Lobashev AV; Ivanova DV; Krukovskaya LL; Yankovsky NK; Kozlov AP In silico screening for tumour-specific expressed sequences in human genome	3	1
445	2	242 2001 GENE 274(1-2):245-252 Dear TN; Boehm T Identification and characterization of two novel calpain large subunit genes	5	1
446	2	243 2001 GENE 275(1):31-37 Osada N; Hida M; Kususda J; Tanuma R; Iseki K; Hirata M; Suto Y; Hirai M; Terao K; Suzuki Y; Sugano S; Hashimoto K Assignment of 118 novel cDNAs of cynomolgus monkey brain to human chromosomes	5	1
447	2	251 2001 GENE 277(1-2):49-62 Sturm RA; Teasdale RD; Box NF Human pigmentation genes: identification, structure and consequences of polymorphic variation	14	1
448	2	252 2001 GENE 278(1-2):41-51 Yuan TTT; Toy P; McClary JA; Lin RJ; Miyamoto NG; Kretschmer PJ Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species	2	1
449	2	258 2001 GENETICA 111(1-3):3-23 Danzmann RG; Gharbi K Gene mapping in fishes: a means to an end	1	1
450	1	259 2001 GENETICA 111(1-3):43-58 Devlin RH; Biagi CA; Smailus DE Genetic mapping of Y-chromosomal DNA markers in Pacific salmon	5	1
451	1	261 2001 GENETICAL RESEARCH 78(2):121-136 Maside X; Bartolome C; Assimacopoulos S; Charlesworth B Rates of movement and distribution of transposable elements in Drosophila melanogaster: in situ hybridization vs Southern blotting data	8	1
452	1	262 2001 GENETICS 158(2):735-746 Voss SR; Smith JJ; Gardiner DM; Parichy DM Conserved vertebrate chromosome segments in the large salamander genome	4	1
453	1	267 2001 GENETICS 159(2):581-588 Noor MAF; Cunningham AL; Larkin JC Consequences of recombination rate variation on quantitative trait locus mapping studies: Simulations based on the Drosophila melanogaster genome	9	1
454	2	272 2001 GENETICS IN MEDICINE 3(6):426-429 McCabe ERB Clinical genetics: Compassion, access, science, and advocacy	3	1
455	2	275 2001 GENOME RESEARCH 11(5):641-643 Collins FS Contemplating the end of the beginning	11	1
456	3	289 2001 GENOME RESEARCH 11(9):1461-1462 Pevzner PA Assembling puzzles from preassembled blocks	1	1
457	2	292 2001 GENOME RESEARCH 11(10):1619-1623 Cai WW; Chen R; Gibbs RA; Bradley A A clone-array pooled shotgun strategy for sequencing large genomes	1	1
458	2	303 2001 GENOME RESEARCH 11(11):1899-1912 Tugendreich S; Perkins E; Couto J; Barthmaier P; Sun DX; Tang S; Tulac S; Nguyen A; Yeh E; Mays A; Wallace E; Lila T; Shivak D; Prichard M; Andrejka L; Kim R; Melese T A streamlined process to phenotypically profile heterologous cDNAs in parallel using yeast cell-based assays	2	1
459	2	304 2001 GENOME RESEARCH 11(11):1913-1925 Cutler DJ; Zwick ME; Carrasquillo MM; Yohn CT; Tobin KP; Kashuk C; Mathews DJ; Shah NA; Eichler EE; Warrington JA; Chakravarti A High-throughput variation detection and genotyping using microarrays	16	1
460	3	307 2001 GENOME RESEARCH 11(12):1975-1977 Wong GKS; Passey DA; Yu J Most of the human genome is transcribed	4	1
461	2	314 2001 GENOMICS 77(1-2):65-70 Kenmochi N; Suzuki T; Uechi T; Magoori M; Kuniba M; Higa S; Watanabe K; Tanaka T The human mitochondrial ribosomal protein genes: Mapping of 54 genes to the chromosomes and implications for human disorders	5	1
462	1	347 2001 IMMUNOLOGICAL REVIEWS 184():69-81 Barclay AN Biochemical analysis of the lymphocyte cell surface - from alloantisera to the role of membrane proteins	1	1
463	2	356 2001 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 286(18):2289-2295 McKusick VA The anatomy of the human genome - A neo-Vesalian basis for medicine in the 21st century	5	1
464	1	363 2001 JOURNAL OF BIOCHEMISTRY 130(3):385-392 Sun JY; Muto A; Hoshino H; Kobayashi A; Nishimura S; Yamamoto M; Hayashi N; Ito E; Igarashi K The promoter of mouse transcription repressor bach1 is regulated by Sp1 and trans-activated by Bach1	3	1
465	2	365 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(25):23161-23172 Kraev A; Quednau BD; Leach S; Li XF; Dong H; Winkfein R; Perizzolo M; Cai XJ; Yang RM; Philipson KD; Lytton J Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3	18	1
466	2	366 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(27):25503-25511 Zhou TY; Chiang CM The intronless and TATA-less human TAF(II)55 gene contains a functional initiator and a downstream promoter element	8	1
467	1	369 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(37):35123-35132 Langbein L; Rogers MA; Winter H; Praetzel S; Schweizer J The catalog of human hair keratins - II. Expression of the six type II members in the hair follicle and the combined catalog of human type I and II keratins	21	1
468	2	378 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(46):43216-43220 Zhang Q; Fan JS; Zhang MJ Interdomain chaperoning between PSD-95, Dlg, and Zo-1 (PDZ) domains of glutamate receptor-interacting proteins	7	1
469	1	382 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(50):46685-46688 Hernandez H; Robinson CV Dynamic protein complexes: Insights from mass spectrometry	12	1
470	5	397 2001 JOURNAL OF HEREDITY 92(6):462-468 Eichler EE; Johnson ME; Alkan C; Tuzun E; Sahinalp C; Misceo D; Archidiacono N; Rocchi M Divergent origins and concerted expansion of two segmental duplications on chromosome 16	2	1
471	2	399 2001 JOURNAL OF LIPID RESEARCH 42(7):1007-1017 Dean M; Hamon Y; Chimini G The human ATP-binding cassette (ABC) transporter superfamily	64	1
472	1	407 2001 JOURNAL OF MOLECULAR ENDOCRINOLOGY 27(3):357-366 Goodyer CG; Zheng H; Hendy GN Alu elements in human growth hormone receptor gene 5 ' untranslated region exons	1	1
473	2	408 2001 JOURNAL OF MOLECULAR EVOLUTION 53(2):160-162 Finta C; Zaphiropoulos PG A statistical view of genome transcription?	3	1
474	1	412 2001 JOURNAL OF NEURAL TRANSMISSION 108(6):717-746 Lesch KP Molecular foundation of anxiety disorders	5	1
475	2	415 2001 JOURNAL OF PATHOLOGY 195(1):87-96 Frantz GD; Pham TQ; Peale FV; Hillan KJ Detection of novel gene expression in paraffin-embedded tissues by isotopic in situ hybridization in tissue microarrays	7	1
476	2	445 2001 METHODS 25(4):456-462 Trinh BN; Long TI; Laird PW DNA methylation analysis by MethyLight technology	2	1
477	2	446 2001 METHODS OF INFORMATION IN MEDICINE 40(4):346-358 Luscombe NM; Greenbaum D; Gerstein M What is bioinformatics? A proposed definition and overview of the field	6	1
478	1	458 2001 MOLECULAR BIOLOGY AND EVOLUTION 18(12):2213-2224 Lovsin N; Gubensek F; Kordis D Evolutionary dynamics in a novel L2 clade of non-LTR retrotransposons in deuterostomia	4	1
479	2	462 2001 MOLECULAR DIAGNOSIS 6(4):243-252 Subramanian G; Mural R; Hoffman SL; Venter JC; Broder S Microbial disease in humans: A genomic perspective	2	1
480	2	484 2001 NATURE 410(6832):1040-1041 Gilson PR; McFadden GI Genome sequencing - A grin without a cat	1	1
481	1	492 2001 NATURE 413(6855):488-494 Levy GG; Nichols WC; Lian EC; Foroud T; McClintick JN; McGee BM; Yang AY; Siemieniak DR; Stark KR; Gruppo R; Sarode R; Shurin SB; Chandrasekaran V; Stabler SP; Sabio H; Bouhassira EE; Upshaw JD; Ginsburg D; Tsai HM Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura	92	1
482	4	503 2001 NATURE GENETICS 27(3):229-230 Little P The end of all human DNA maps?	3	1
483	4	509 2001 NATURE GENETICS 29(1):4-6 Quackenbush J The power of public access - The human genome project and the scientific process	3	1
484	1	516 2001 NATURE GENETICS 29(4):375-376 Waters VL Conjugation between bacterial and mammalian cells	10	1
485	2	521 2001 NATURE IMMUNOLOGY 2(12):1109-1116 McIntire JJ; Umetsu SE; Akbari O; Potter M; Kuchroo VK; Barsh GS; Freeman GJ; Umetsu DT; DeKruyff RH Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family	26	1
486	1	524 2001 NATURE MEDICINE 7(3):281-283 Liggett SB Pharmacogenetic applications of the Human Genome Project	11	1
487	4	525 2001 NATURE MEDICINE 7(3):283-285 Ratain MJ; Relling MV Gazing into a crystal ball-cancer therapy in the post-genomic era	6	1
488	4	527 2001 NATURE REVIEWS CANCER 1(2):99-108 Relling MV; Dervieux T Pharmacogenetics and cancer therapy	21	1
489	2	532 2001 NATURE REVIEWS GENETICS 2(5):392-396 Roche PA; Annas GJ Opinion - Protecting genetic privacy	10	1
490	1	534 2001 NATURE REVIEWS GENETICS 2(7):528-537 White KP Functional genomics and the study of development, variation and evolution	5	1
491	2	538 2001 NATURE REVIEWS GENETICS 2(9):681-689 Kim SK HTTP ://C-elegans: Mining the functional genomic landscape	7	1
492	1	551 2001 NEUROCHEMICAL RESEARCH 26(12):1293-1299 Zaheer A; Yorek MA; Lim R Effects of glia maturation factor overexpression in primary astrocytes on MAP kinase activation, transcription factor activation, and neurotrophin secretion	1	1
493	2	554 2001 NEW ENGLAND JOURNAL OF MEDICINE 344(8):601-602 Golub TR Genome-wide views of cancer.	9	1
494	1	568 2001 NUCLEIC ACIDS RESEARCH 29(22):4633-4642 Kurtz S; Choudhuri JV; Ohlebusch E; Schleiermacher C; Stoye J; Giegerich R REPuter: the manifold applications of repeat analysis on a genomic scale	6	1
495	3	570 2001 NUCLEIC ACIDS RESEARCH 29(24):4983-4993 Mu XQ; Zhao S; Pershad R; Hsieh TF; Scarpa A; Wang SW; White RA; Beremand PD; Thomas TL; Gan L; Klein WH Gene expression in the developing mouse retina by EST sequencing and microarray analysis	6	1
496	2	588 2001 PHYSIOLOGICAL GENOMICS 6(2):57-80 Das M; Harvey I; Chu LL; Sinha M; Pelletier J Full-length cDNAs: more than just reaching the ends	5	1
497	2	598 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(19):10572-10577 Zhou XB; Marks PA; Rifkind RA; Richon VM Cloning and characterization of a histone deacetylase, HDAC9	46	1
498	3	602 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(21):11837-11838 Strausberg RL; Riggins GJ Navigating the human transcriptome	3	1
499	1	606 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(24):13778-13783 Witte CP; Le QH; Bureau T; Kumar A Terminal-repeat retrotransposons in miniature (TRIM) are involved in restructuring plant genomes	4	1
500	2	612 2001 PROTEIN SCIENCE 10(10):1970-1979 Liu JF; Rost B Comparing function and structure between entire proteomes	23	1

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