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#	Date / Author / Journal	LCS	GCS	LCR	CR
5201	4915 REIS RJS, GOLDSTEIN S INTERCLONAL VARIATION IN METHYLATION PATTERNS FOR EXPRESSED AND NON- EXPRESSED GENES NUCLEIC ACIDS RESEARCH. 1982; 10 (14): 4293-4304	4	32	4	36
5202	4942 BRISSENDEN JE, COX DW ALPHA-2-MACROGLOBULIN PRODUCTION BY CULTURED HUMAN-FIBROBLASTS SOMATIC CELL GENETICS. 1982; 8 (3): 289-305	2	21	4	36
5203	4943 HOFFEE PA, HUNT SW, CHIANG J ISOLATION OF DEOXYCOFORMYCIN-RESISTANT CELLS WITH INCREASED LEVELS OF ADENOSINE-DEAMINASE SOMATIC CELL GENETICS. 1982; 8 (4): 465-477	0	17	4	36
5204	4971 MAYO P, SAHA SP SPONTANEOUS PNEUMOTHORAX IN THE NEWBORN AMERICAN SURGEON. 1983; 49 (4): 192-195	0	5	0	36
5205	5011 ANTECOL MH, MUKHERJEE BB EFFECTS OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE ON FIBROBLASTS FROM INDIVIDUALS GENETICALLY PREDISPOSED TO CANCER - REPLY CANCER RESEARCH. 1983; 43 (11): 5624-5626	0	0	7	36
5206	5035 SWENNE I EFFECTS OF AGING ON THE REGENERATIVE CAPACITY OF THE PANCREATIC B-CELL OF THE RAT DIABETES. 1983; 32 (1): 14-19	1	108	3	36
5207	5236 THOMAS R, KAPLAN L, REICH N, LANE DP, LEVINE AJ CHARACTERIZATION OF HUMAN P53-ANTIGENS EMPLOYING PRIMATE SPECIFIC MONOCLONAL-ANTIBODIES VIROLOGY. 1983; 131 (2): 502-517	1	69	3	36
5208	5258 LEDBETTER MLS INCREASED OUABAIN SENSITIVITY OF CULTURED HUMAN-FIBROBLASTS FROM MUSCULAR-DYSTROPHY AMERICAN JOURNAL OF PHYSIOLOGY. 1984; 247 (5): C415-C423	0	4	3	36
5209	5263 ZGORNIAKNOWOSIELSKA I, BIELANSKI W, KOSINIAK K MYCOPLASMAS IN STALLION SEMEN ANIMAL REPRODUCTION SCIENCE. 1984; 7 (4): 343-350	1	7	4	36
5210	5490 GERFAUX J, MACE B, CHANYFOURNIER F, POMPIDOU A EARLY NUCLEAR STRUCTURAL-CHANGES OF TRANSFORMED HUMAN AMNIOTIC CELLS (WISH) IN PRESENCE OF TYPE-IV COLLAGEN DETECTED BY THE NUCLEAR REFRINGENCY ASSAY PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE. 1984; 176 (4): 490-502	0	4	0	36
#	Date / Author / Journal	LCS	GCS	LCR	CR
5211	5503 BOGGS DR, SAXE DF, BOGGS SS AGING AND HEMATOPOIESIS .2. THE ABILITY OF BONE-MARROW CELLS FROM YOUNG AND AGED MICE TO CURE AND MAINTAIN CURE IN W/WV TRANSPLANTATION. 1984; 37 (3): 300-306	4	24	14	36
5212	5749 BUNN CL, WHITE FA, OGUIN WM, SAWYER RH, KNAPP LW INTERMEDIATE FILAMENT EXPRESSION AND LIFE-SPAN POTENTIAL IN HUMAN SOMATIC-CELL HYBRIDS IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY. 1985 DEC; 21 (12): 716-720	1	4	6	36
5213	5806 CANAANI D, NAIMAN T, TEITZ T, BERG P IMMORTALIZATION OF XERODERMA PIGMENTOSUM-CELLS BY SIMIAN VIRUS-40 DNA HAVING A DEFECTIVE ORIGIN OF DNA-REPLICATION SOMATIC CELL AND MOLECULAR GENETICS. 1986 JAN; 12 (1): 13-20	5	42	5	36
5214	5892 LUMPKIN CK, KNEPPER JE, BUTEL JS, SMITH JR, PEREIRASMITH OM MITOGENIC EFFECTS OF THE PROTOONCOGENE AND ONCOGENE FORMS OF C-H-RAS DNA IN HUMAN-DIPLOID FIBROBLASTS MOLECULAR AND CELLULAR BIOLOGY. 1986 AUG; 6 (8): 2990-2993	13	38	14	36
5215	5998 AUFDERHEIDE KJ CLONAL AGING IN PARAMECIUM-TETRAURELIA .2. EVIDENCE OF FUNCTIONAL- CHANGES IN THE MACRONUCLEUS WITH AGE MECHANISMS OF AGEING AND DEVELOPMENT. 1987 JAN; 37 (3): 265-279	3	10	9	36
5216	6012 TAKAGI Y, SUZUKI T, SHIMADA C ISOLATION OF A PARAMECIUM-TETRAURELIA MUTANT WITH SHORT CLONAL LIFE- SPAN AND WITH NOVEL LIFE-CYCLE FEATURES ZOOLOGICAL SCIENCE. 1987 FEB; 4 (1): 73-80	3	14	11	36
5217	6111 ROCKWELL GA, JOHNSON G, SIBATANI A INVITRO SENESCENCE OF HUMAN KERATINOCYTE CULTURES CELL STRUCTURE AND FUNCTION. 1987 DEC; 12 (6): 539-548	2	6	6	36
5218	6152 YAMAMOTO K, YAMAMOTO M, OOKA H CHANGES IN NEGATIVE SURFACE-CHARGE OF HUMAN-DIPLOID FIBROBLASTS, TIG-1, DURING INVITRO AGING MECHANISMS OF AGEING AND DEVELOPMENT. 1988 FEB; 42 (2): 183-195	1	1	28	36
5219	6209 SOTTILE J, HOYLE M, MILLIS AJT DIFFERENTIAL RESPONSE OF EARLY AND LATE PASSAGE FIBROBLASTS TO COLLAGENASE STIMULATORY FACTOR IN CONDITIONED MEDIA COLLAGEN AND RELATED RESEARCH. 1988 JUL; 8 (4): 361-374	12	16	8	36
5220	6262 WALKER AP, BACHELARD HS STUDIES ON DNA DAMAGE AND REPAIR IN THE MAMMALIAN BRAIN JOURNAL OF NEUROCHEMISTRY. 1988 NOV; 51 (5): 1394-1399	1	13	3	36
#	Date / Author / Journal	LCS	GCS	LCR	CR
5221	6284 KNOLL J THE PHARMACOLOGY OF SELEGILINE ((-)DEPRENYL) - NEW ASPECTS ACTA NEUROLOGICA SCANDINAVICA. 1989; 80: 83-91	0	8	1	36
5222	6289 SCHJEIDE OA, GRIFFITHS TD, MORRISON LM EFFECTS OF CHONDROITIN-4-SULFATE ON SURVIVAL, SIZES AND ULTRASTRUCTURES OF CULTURED WI-38 FIBROBLASTS AND FIBROBLASTS FROM PROGERIA PATIENTS CYTOBIOS. 1989; 59 (236): 39-60	0	0	3	36
5223	6295 HILL MW, KARTHIGASAN J GLUCOSE-METABOLISM AND PROTEIN-SYNTHESIS IN STRATIFIED SQUAMOUS EPITHELIA FROM YOUNG AND OLD MICE EXPERIMENTAL GERONTOLOGY. 1989; 24 (4): 331-340	0	3	4	36
5224	6419 GILCHREST BA SKIN AGING AND PHOTOAGING - AN OVERVIEW JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. 1989 SEP; 21 (3): 610-613	3	155	15	36
5225	6507 PORTER MB, PEREIRASMITH OM, SMITH JR NOVEL MONOCLONAL-ANTIBODIES IDENTIFY ANTIGENIC DETERMINANTS UNIQUE TO CELLULAR SENESCENCE JOURNAL OF CELLULAR PHYSIOLOGY. 1990 FEB; 142 (2): 425-433	15	23	24	36
5226	6519 JAMASBI RJ, PERKINS EH BIOLOGICAL HETEROGENEITY AND RADIATION SENSITIVITY OF INVITRO PROPAGATED LUNG METASTATIC LINES ORIGINATED FROM A TRANSPLANTABLE SQUAMOUS-CELL CARCINOMA OF BALB/C MOUSE IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY. 1990 MAR; 26 (3): 222-228	1	7	1	36
5227	6553 RIZZINO A, KAZAKOFF P, NEBELSICK J DENSITY-INDUCED DOWN REGULATION OF EPIDERMAL GROWTH-FACTOR RECEPTORS IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY. 1990 MAY; 26 (5): 537-542	0	30	2	36
5228	6725 NING Y, PEREIRASMITH OM MOLECULAR GENETIC APPROACHES TO THE STUDY OF CELLULAR SENESCENCE MUTATION RESEARCH. 1991 MAR-NOV; 256 (2-6): 303-310	18	24	20	36
5229	6734 CHEN SC, CHOU CK, WONG FH, CHANG CM, HU CP OVEREXPRESSION OF EPIDERMAL GROWTH-FACTOR AND INSULIN-LIKE GROWTH FACTOR-I RECEPTORS AND AUTOCRINE STIMULATION IN HUMAN ESOPHAGEAL- CARCINOMA CELLS CANCER RESEARCH. 1991 APR 1; 51 (7): 1898-1903	0	55	2	36
5230	6897 PHILLIPS PD, PIGNOLO RJ, NISHIKURA K, CRISTOFALO VJ RENEWED DNA-SYNTHESIS IN SENESCENT WI-38-CELLS BY EXPRESSION OF AN INDUCIBLE CHIMERIC C-FOS CONSTRUCT JOURNAL OF CELLULAR PHYSIOLOGY. 1992 APR; 151 (1): 206-212	31	40	11	36
#	Date / Author / Journal	LCS	GCS	LCR	CR
5231	6907 HARRIS JR, PEDERSEN NL, MCCLEARN GE, PLOMIN R, NESSELROADE JR AGE-DIFFERENCES IN GENETIC AND ENVIRONMENTAL-INFLUENCES FOR HEALTH FROM THE SWEDISH ADOPTION TWIN STUDY OF AGING JOURNALS OF GERONTOLOGY. 1992 MAY; 47 (3): P213-P220	1	34	3	36
5232	6926 PIGNOLO RJ, MASORO EJ, NICHOLS WW, BRADT CI, CRISTOFALO VJ SKIN FIBROBLASTS FROM AGED FISCHER-344 RATS UNDERGO SIMILAR CHANGES IN REPLICATIVE LIFE-SPAN BUT NOT IMMORTALIZATION WITH CALORIC RESTRICTION OF DONORS EXPERIMENTAL CELL RESEARCH. 1992 JUL; 201 (1): 16-22	12	21	14	36
5233	7157 SUZUKI T, MIYAZAWA T, FUJIMOTO K, OTSUKA M, TSUTSUMI M AGE-RELATED ACCUMULATION OF PHOSPHATIDYLCHOLINE HYDROPEROXIDE IN CULTURED HUMAN-DIPLOID CELLS AND ITS PREVENTION BY ALPHA-TOCOPHEROL LIPIDS. 1993 AUG; 28 (8): 775-778	1	24	6	36
5234	7245 KONISHI I, FENDRICK JL, PARMLEY TH, QUIRK JG, OBRIEN TJ EPIDERMAL GROWTH-FACTOR ENHANCES SECRETION OF THE OVARIAN TUMOR- ASSOCIATED CANCER ANTIGEN CA125 FROM THE HUMAN AMNION WISH CELL-LINE JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION. 1994 JAN-MAR; 1 (1): 89-96	0	10	4	36
5235	7263 KILL IR, FARAGHER RGA, LAWRENCE K, SHALL S THE EXPRESSION OF PROLIFERATION-DEPENDENT ANTIGENS DURING THE LIFE-SPAN OF NORMAL AND PROGEROID HUMAN FIBROBLASTS IN CULTURE JOURNAL OF CELL SCIENCE. 1994 FEB; 107: 571-579	24	59	12	36
5236	7279 EFFROS RB, ZHU XM, WALFORD RL STRESS-RESPONSE OF SENESCENT T-LYMPHOCYTES - REDUCED HSP70 IS INDEPENDENT OF THE PROLIFERATIVE BLOCK JOURNALS OF GERONTOLOGY. 1994 MAR; 49 (2): B65-B70	10	43	7	36
5237	7309 TOKUMITSU M, KADOHAMA T, OGAWA K INFREQUENT LOSS OF HETEROZYGOSITY AND MUTATION OF THE P53 GENE IN IMMORTAL AND TRANSFORMED MOUSE EMBRYO FIBROBLASTS MOLECULAR CARCINOGENESIS. 1994 MAY; 10 (1): 52-57	3	11	6	36
5238	7312 LIU XT, STEWART CA, KING RL, DANNER DA, DELLORCO RT, et al. PROHIBITIN EXPRESSION DURING CELLULAR SENESCENCE OF HUMAN-DIPLOID FIBROBLASTS BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1994 MAY 30; 201 (1): 409-414	7	40	11	36
5239	7321 SANDHU AK, HUBBARD K, KAUR GP, JHA KK, OZER HL, et al. SENESCENCE OF IMMORTAL HUMAN FIBROBLASTS BY THE INTRODUCTION OF NORMAL HUMAN-CHROMOSOME-6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1994 JUN 7; 91 (12): 5498-5502	56	101	16	36
5240	7337 IKRAM Z, NORTON T, JAT PS THE BIOLOGICAL CLOCK THAT MEASURES THE MITOTIC LIFE-SPAN OF MOUSE EMBRYO FIBROBLASTS CONTINUES TO FUNCTION IN THE PRESENCE OF SIMIAN- VIRUS-40 LARGE TUMOR-ANTIGEN PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1994 JUL 5; 91 (14): 6448-6452	11	30	17	36
#	Date / Author / Journal	LCS	GCS	LCR	CR
5241	7339 OHNEDA K, FUKUDA M, SHIMADA N, ISHIKAWA N, ICHOU T, et al. INCREASED EXPRESSION OF NUCLEOSIDE DIPHOSPHATE KINASES NM23 IN HUMAN- DIPLOID FIBROBLASTS TRANSFORMED BY SV40 LARGE T-ANTIGEN OR CO-60 IRRADIATION FEBS LETTERS. 1994 JUL 18; 348 (3): 273-277	0	22	6	36
5242	7363 HODGES DJ, LEE DC, SALTER CJ, REID DG, HARPER GP, et al. PURIFICATION AND SECONDARY STRUCTURAL-ANALYSIS OF TISSUE INHIBITOR OF METALLOPROTEINASES-1 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY. 1994 SEP 21; 1208 (1): 94-100	0	7	1	36
5243	7460 KAUL SC, WADHWA R, MATSUDA Y, HENSLER PJ, PEREIRASMITH OM, et al. MOUSE AND HUMAN CHROMOSOMAL ASSIGNMENTS OF MORTALIN, A NOVEL MEMBER OF THE MURINE HSP70 FAMILY OF PROTEINS FEBS LETTERS. 1995 MAR 20; 361 (2-3): 269-272	1	19	16	36
5244	7465 SAITO H, HAMMOND AT, MOSES RE THE EFFECT OF LOW-OXYGEN TENSION ON THE IN-VITRO REPLICATIVE LIFE-SPAN OF HUMAN-DIPLOID FIBROBLAST CELLS AND THEIR TRANSFORMED DERIVATIVES EXPERIMENTAL CELL RESEARCH. 1995 APR; 217 (2): 272-279	33	65	22	36
5245	7561 ZWICKER J, LUCIBELLO FC, WOLFRAIM LA, GROSS C, TRUSS M, et al. CELL-CYCLE REGULATION OF THE CYCLIN-A, CDC25C AND CDC2 GENES IS BASED ON A COMMON MECHANISM OF TRANSCRIPTIONAL REPRESSION EMBO JOURNAL. 1995 SEP 15; 14 (18): 4514-4522	1	240	2	36
5246	7615 Kroll J The ATPase module and the process of cellular immortalization PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS. 1996; 786: 57-61	0	2	11	36
5247	7638 Smith JR, Nakanishi M, Robetorye RS, Venable SF, PereiraSmith OM Studies demonstrating the complexity of regulation and action of the growth inhibitory gene SDI1 EXPERIMENTAL GERONTOLOGY. 1996 JAN-APR; 31 (1-2): 327-335	4	6	12	36
5248	7722 Zahn RK, Jaud S, Schroder HC, ZahnDaimler G DNA status in brain and heart as prominent co-determinant for life span? Assessing the different degrees of DNA damage, damage susceptibility, and repair capability in different organs of young and old mice MECHANISMS OF AGEING AND DEVELOPMENT. 1996 AUG 15; 89 (2): 79-94	2	16	6	36
5249	7782 Tsushida T, Shinohara K Evaluation of physiological functionalities of horticultural products using mammalian cell culture JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI. 1997; 44 (9): 607-614	0	1	2	36
5250	7784 Kassem M, Ankersen L, Eriksen EF, Clark BFC, Rattan SIS Demonstration of cellular aging and senescence in serially passaged long-term cultures of human trabecular osteoblasts OSTEOPOROSIS INTERNATIONAL. 1997; 7 (6): 514-524	9	50	6	36
#	Date / Author / Journal	LCS	GCS	LCR	CR
5251	7823 Haas C, Aicher WK, Dinkel A, Peter HH, Eibel H Characterization of SV40T antigen immortalized human synovial fibroblasts: Maintained expression patterns of EGR-1, HLA-DR and some surface receptors RHEUMATOLOGY INTERNATIONAL. 1997 MAR; 16 (6): 241-247	0	29	11	36
5252	7831 Higami Y, Shimokawa I, Okimoto T, Tomita M, Yuo T, et al. Effect of aging and dietary restriction on hepatocyte proliferation and death in male F344 rats CELL AND TISSUE RESEARCH. 1997 APR; 288 (1): 69-77	1	23	5	36
5253	7844 Zhang BX, Shih JWK, Wear DJ, Tsai S, Lo SC High-level expression of H-ras and c-myc oncogenes in Mycoplasma- mediated malignant cell transformation PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE. 1997 APR; 214 (4): 359-366	4	20	4	36
5254	7872 Chatelut M, Harzer K, Christomanou H, Feunteun J, Pieraggi MT, et al. Model SV40-transformed fibroblast lines for metabolic studies of human prosaposin and acid ceramidase deficiencies CLINICA CHIMICA ACTA. 1997 JUN 27; 262 (1-2): 61-76	0	24	2	36
5255	7890 Brown JP, Wei WY, Sedivy JM Bypass of senescence after disruption of p21(CIP1/WAF1) gene in normal diploid human fibroblasts SCIENCE. 1997 AUG 8; 277 (5327): 831-834	132	426	18	36
5256	7931 Tahara H, Tokutake Y, Maeda S, Kataoka H, Watanabe T, et al. Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus ONCOGENE. 1997 OCT 16; 15 (16): 1911-1920	19	98	5	36
5257	8132 Savageau MA Demand theory of gene regulation. II. Quantitative application to the lactose and maltose operons of Escherichia coli GENETICS. 1998 AUG; 149 (4): 1677-1691	2	21	1	36
5258	8153 Suzuki M, Yang Z, Nakano K, Yatagai F, Suzuki K, et al. Extension of in vitro life-span of gamma-irradiated human embryo cells accompanied by chromosome instability JOURNAL OF RADIATION RESEARCH. 1998 SEP; 39 (3): 203-213	2	10	11	36
5259	8242 Fodil-Bourahla I, Drubaix I, Robert L Effect of in vitro aging on the biosynthesis of glycosaminoglycans by human skin fibroblasts. Modulation by the elastin-laminin receptor MECHANISMS OF AGEING AND DEVELOPMENT. 1999 JAN 15; 106 (3): 241-260	2	10	2	36
5260	8264 Vaziri H, Squire JA, Pandita TK, Bradley G, Kuba RM, et al. Analysis of genomic integrity and p53-dependent G(1) checkpoint in telomerase-induced extended-life-span human fibroblasts MOLECULAR AND CELLULAR BIOLOGY. 1999 MAR; 19 (3): 2373-2379	29	79	14	36
#	Date / Author / Journal	LCS	GCS	LCR	CR
5261	8297 Biecker E, Schachtschabel DO Diminished stimulation of glycosaminoglycan synthesis of cultured human skin fibroblasts during in vitro aging by interleukin-1 ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE. 1999 APR; 32 (2): 124-130	1	2	9	36
5262	8298 Wei S, Wei WY, Sedivy JM Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts CANCER RESEARCH. 1999 APR 1; 59 (7): 1539-1543	46	92	21	36
5263	8326 Lewis K Human longevity: an evolutionary approach MECHANISMS OF AGEING AND DEVELOPMENT. 1999 JUN 1; 109 (1): 43-51	2	12	3	36
5264	8353 Waldo RH, Popham PL, Romero-Arroyo CE, Mothershed EA, Lee KK, et al. Transcriptional analysis of the hmw gene cluster of Mycoplasma pneumoniae JOURNAL OF BACTERIOLOGY. 1999 AUG; 181 (16): 4978-4985	2	15	10	36
5265	8404 Chung CY, Iida-Klein A, Wyatt LE, Rudkin GH, Ishida K, et al. Serial passage of MC3T3-E1 cells alters osteoblastic function and responsiveness to transforming growth factor-beta 1 and bone morphogenetic protein-2 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999 NOV 11; 265 (1): 246-251	0	40	4	36
5266	8407 Feikin DR, Moroney JF, Talkington DF, Thacker WL, Code JE, et al. An outbreak of acute respiratory disease caused by Mycoplasma pneumoniae and adenovirus at a federal service training academy: New implications from an old scenario CLINICAL INFECTIOUS DISEASES. 1999 DEC; 29 (6): 1545-1550	2	24	11	36
5267	8408 Terman A, Dalen H, Brunk UT Ceroid/lipofuscin-loaded human fibroblasts show decreased survival time and diminished autophagocytosis during amino acid starvation EXPERIMENTAL GERONTOLOGY. 1999 DEC; 34 (8): 943-957	2	50	8	36
5268	8559 Waters DJ, Shen SR, Glickman LT Life expectancy, antagonistic pleiotropy, and the testis of dogs and men PROSTATE. 2000 JUN 1; 43 (4): 272-277	1	9	2	36
5269	8629 Sheng ZJ, Sun WP, Smith E, Cohen C, Sheng Z, et al. Restoration of positioning control following Disabled-2 expression in ovarian and breast tumor cells ONCOGENE. 2000 OCT 5; 19 (42): 4847-4854	0	49	2	36
5270	8670 Muravchick S Gero-anesthesia: Functional reserve, cardiovascular changes, and postoperative complications ANAESTHESIA PAIN INTENSIVE CARE AND EMERGENCY MEDICINE - APICE 15. 2001; : 555-567	0	0	1	36
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5271	8766 Kim H, You SK, Kim IJ, Foster LK, Farris J, et al. Alterations in p53 and E2F-1 function common to immortalized chicken embryo fibroblasts ONCOGENE. 2001 MAY 10; 20 (21): 2671-2682	7	26	10	36
5272	8851 Adelfalk C, Lorenz M, Serra V, von Zglinicki T, Hirsch-Kauffmann M, et al. Accelerated telomere shortening in Fanconi anemia fibroblasts - a longitudinal study FEBS LETTERS. 2001 SEP 28; 506 (1): 22-26	10	29	9	36
5273	8889 Roske K, Blanchard A, Chambaud I, Citti C, Helbig JH, et al. Phase variation among major surface antigens of Mycoplasma penetrans INFECTION AND IMMUNITY. 2001 DEC; 69 (12): 7642-7651	0	18	4	36
5274	8990 Harvey SA, Jensen KO, Elmore LW, Holt SE Pharmacological approaches to defining the role of chaperones in aging and prostate cancer progression CELL STRESS & CHAPERONES. 2002 APR; 7 (2): 230-234	1	3	6	36
5275	9009 Joguchi A, Otsuka I, Minagawa S, Suzuki T, Fujii M, et al. Overexpression of VDUP1 mRNA sensitizes HeLa cells to paraquat BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002 APR 26; 293 (1): 293-297	0	16	7	36
5276	9064 Badovinac VP, Porter BB, Harty JT Programmed contraction of CD8(+) T cells after infection NATURE IMMUNOLOGY. 2002 JUL; 3 (7): 619-626	4	313	1	36
5277	9127 Egorov EE, Terekhov SM, Vishnyakova KS, Karachentsev DN, El'darov MA, et al. Immortalization of normal dermal fibroblasts of adult person via introduction of gene of catalytic subunit of telomerase BIOLOGICHESKIE MEMBRANY. 2002 NOV-DEC; 19 (6): 483-490	0	2	11	36
5278	9311 Merker K, Ullrich O, Schmidt H, Sitte N, Grune T Stability of the nuclear protein turnover during cellular senescence of human fibroblasts FASEB JOURNAL. 2003 AUG; 17 (11): 1963-+	2	20	4	36
5279	9317 Evans RJ, Wyllie FS, Wynford-Thomas D, Kipling D, Jones CJ A p53-dependent, telomere-independent proliferative life span barrier in human astrocytes consistent with the molecular genetics of glioma development CANCER RESEARCH. 2003 AUG 15; 63 (16): 4854-4861	5	21	16	36
5280	9319 Kashino G, Kodama S, Nakayama Y, Suzuki K, Fukase K, et al. Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells FREE RADICAL BIOLOGY AND MEDICINE. 2003 AUG 15; 35 (4): 438-443	6	24	11	36
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5281	9339 Yamamoto A, Kumakura S, Uchida M, Barrett JC, Tsutsui T Immortalization of normal human embryonic fibroblasts by introduction of either the human papillomavirus type 16 E6 or E7 gene alone INTERNATIONAL JOURNAL OF CANCER. 2003 SEP 1; 106 (3): 301-309	1	18	12	36
5282	9389 Balish MF, Ross SM, Fisseha M, Krause DC Deletion analysis identifies key functional domains of the cytadherence-associated protein HMW2 of Mycoplasma pneumoniae MOLECULAR MICROBIOLOGY. 2003 DEC; 50 (5): 1507-1516	1	14	17	36
5283	9470 Dillon BJ, Prieto VG, Curley SA, Ensor CM, Holtsberg FW, et al. Incidence and distribution of argininosuccinate synthetase deficiency in human cancers - A method for identifying cancers sensitive to arginine deprivation CANCER. 2004 FEB 15; 100 (4): 826-833	2	47	7	36
5284	9544 Holliday R The multiple and irreversible causes of aging JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2004 JUN; 59 (6): 568-572	3	8	8	36
5285	9738 Terai M, Uyama T, Sugiki T, Li XK, Umezawa A, et al. Immortalization of human fetal cells: The life span of umbilical cord blood-derived cells can be prolonged without manipulating p16(INK4a)/RB braking pathway MOLECULAR BIOLOGY OF THE CELL. 2005 MAR; 16 (3): 1491-1499	5	36	7	36
5286	9797 Kitagawa J, Kanda K, Sugiura M, Tsuboi Y, Ogawa A, et al. Effect of chronic inflammation on dorsal horn nociceptive neurons in aged rats JOURNAL OF NEUROPHYSIOLOGY. 2005 JUN; 93 (6): 3594-3604	1	16	1	36
5287	9824 Hiyama K, Otani K, Ohtaki M, Satoh K, Kumazaki T, et al. Differentially expressed genes throughout the cellular immortalization processes are quite different between normal human fibroblasts and endothelial cells INTERNATIONAL JOURNAL OF ONCOLOGY. 2005 JUL; 27 (1): 87-95	0	8	7	36
5288	10030 Vesper BJ, Lee S, Hammer ND, Elseth KM, Barrett AGM, et al. Developing a structure-function relationship for anionic porphyrazines exhibiting selective anti-tumor activity JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY. 2006 MAR 1; 82 (3): 180-186	0	8	3	36
5289	10061 Jin X, Lee JS, Kwak S, Jung JE, Kim TK, et al. Myogenic differentiation of p53-and Rb-deficient immortalized and transformed bovine fibroblasts in response to myoD MOLECULES AND CELLS. 2006 APR 30; 21 (2): 206-212	0	8	11	36
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5292	10168 Sasaki T, Maier B, Bartke A, Scrable H Progressive loss of SIRT1 with cell cycle withdrawal AGING CELL. 2006 OCT; 5 (5): 413-422	5	51	7	36
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5296	10739 Ilmonen P, Kotrschal A, Penn DJ Telomere Attrition Due to Infection PLOS ONE. 2008 MAY 14; 3 (5): Art. No. e2143	1	20	8	36
5297	10741 Lu T, Finkel T Free radicals and senescence EXPERIMENTAL CELL RESEARCH. 2008 MAY 15; 314 (9): 1918-1922	10	44	10	36
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5201

4915 REIS RJS, GOLDSTEIN S

INTERCLONAL VARIATION IN METHYLATION PATTERNS FOR EXPRESSED AND NON- EXPRESSED GENES

NUCLEIC ACIDS RESEARCH. 1982; 10 (14): 4293-4304

5202

4942 BRISSENDEN JE, COX DW

ALPHA-2-MACROGLOBULIN PRODUCTION BY CULTURED HUMAN-FIBROBLASTS

SOMATIC CELL GENETICS. 1982; 8 (3): 289-305

5203

4943 HOFFEE PA, HUNT SW, CHIANG J

ISOLATION OF DEOXYCOFORMYCIN-RESISTANT CELLS WITH INCREASED LEVELS OF ADENOSINE-DEAMINASE

SOMATIC CELL GENETICS. 1982; 8 (4): 465-477

5204

4971 MAYO P, SAHA SP

SPONTANEOUS PNEUMOTHORAX IN THE NEWBORN

AMERICAN SURGEON. 1983; 49 (4): 192-195

5205

5011 ANTECOL MH, MUKHERJEE BB

EFFECTS OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE ON FIBROBLASTS FROM INDIVIDUALS GENETICALLY PREDISPOSED TO CANCER - REPLY

CANCER RESEARCH. 1983; 43 (11): 5624-5626

5206

5035 SWENNE I

EFFECTS OF AGING ON THE REGENERATIVE CAPACITY OF THE PANCREATIC B-CELL OF THE RAT

DIABETES. 1983; 32 (1): 14-19

108

5207

5236 THOMAS R, KAPLAN L, REICH N, LANE DP, LEVINE AJ

CHARACTERIZATION OF HUMAN P53-ANTIGENS EMPLOYING PRIMATE SPECIFIC MONOCLONAL-ANTIBODIES

VIROLOGY. 1983; 131 (2): 502-517

5208

5258 LEDBETTER MLS

INCREASED OUABAIN SENSITIVITY OF CULTURED HUMAN-FIBROBLASTS FROM MUSCULAR-DYSTROPHY

AMERICAN JOURNAL OF PHYSIOLOGY. 1984; 247 (5): C415-C423

5209

5263 ZGORNIAKNOWOSIELSKA I, BIELANSKI W, KOSINIAK K

MYCOPLASMAS IN STALLION SEMEN

ANIMAL REPRODUCTION SCIENCE. 1984; 7 (4): 343-350

5210

5490 GERFAUX J, MACE B, CHANYFOURNIER F, POMPIDOU A

EARLY NUCLEAR STRUCTURAL-CHANGES OF TRANSFORMED HUMAN AMNIOTIC CELLS (WISH) IN PRESENCE OF TYPE-IV COLLAGEN DETECTED BY THE NUCLEAR REFRINGENCY ASSAY

PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE. 1984; 176 (4): 490-502

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5211

5503 BOGGS DR, SAXE DF, BOGGS SS

AGING AND HEMATOPOIESIS .2. THE ABILITY OF BONE-MARROW CELLS FROM YOUNG AND AGED MICE TO CURE AND MAINTAIN CURE IN W/WV

TRANSPLANTATION. 1984; 37 (3): 300-306

5212

5749 BUNN CL, WHITE FA, OGUIN WM, SAWYER RH, KNAPP LW

INTERMEDIATE FILAMENT EXPRESSION AND LIFE-SPAN POTENTIAL IN HUMAN SOMATIC-CELL HYBRIDS

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY. 1985 DEC; 21 (12): 716-720

5213

5806 CANAANI D, NAIMAN T, TEITZ T, BERG P

IMMORTALIZATION OF XERODERMA PIGMENTOSUM-CELLS BY SIMIAN VIRUS-40 DNA HAVING A DEFECTIVE ORIGIN OF DNA-REPLICATION

SOMATIC CELL AND MOLECULAR GENETICS. 1986 JAN; 12 (1): 13-20

5214

5892 LUMPKIN CK, KNEPPER JE, BUTEL JS, SMITH JR, PEREIRASMITH OM

MITOGENIC EFFECTS OF THE PROTOONCOGENE AND ONCOGENE FORMS OF C-H-RAS DNA IN HUMAN-DIPLOID FIBROBLASTS

MOLECULAR AND CELLULAR BIOLOGY. 1986 AUG; 6 (8): 2990-2993

5215

5998 AUFDERHEIDE KJ

CLONAL AGING IN PARAMECIUM-TETRAURELIA .2. EVIDENCE OF FUNCTIONAL- CHANGES IN THE MACRONUCLEUS WITH AGE

MECHANISMS OF AGEING AND DEVELOPMENT. 1987 JAN; 37 (3): 265-279

5216

6012 TAKAGI Y, SUZUKI T, SHIMADA C

ISOLATION OF A PARAMECIUM-TETRAURELIA MUTANT WITH SHORT CLONAL LIFE- SPAN AND WITH NOVEL LIFE-CYCLE FEATURES

ZOOLOGICAL SCIENCE. 1987 FEB; 4 (1): 73-80

5217

6111 ROCKWELL GA, JOHNSON G, SIBATANI A

INVITRO SENESCENCE OF HUMAN KERATINOCYTE CULTURES

CELL STRUCTURE AND FUNCTION. 1987 DEC; 12 (6): 539-548

5218

6152 YAMAMOTO K, YAMAMOTO M, OOKA H

CHANGES IN NEGATIVE SURFACE-CHARGE OF HUMAN-DIPLOID FIBROBLASTS, TIG-1, DURING INVITRO AGING

MECHANISMS OF AGEING AND DEVELOPMENT. 1988 FEB; 42 (2): 183-195

5219

6209 SOTTILE J, HOYLE M, MILLIS AJT

DIFFERENTIAL RESPONSE OF EARLY AND LATE PASSAGE FIBROBLASTS TO COLLAGENASE STIMULATORY FACTOR IN CONDITIONED MEDIA

COLLAGEN AND RELATED RESEARCH. 1988 JUL; 8 (4): 361-374

5220

6262 WALKER AP, BACHELARD HS

STUDIES ON DNA DAMAGE AND REPAIR IN THE MAMMALIAN BRAIN

JOURNAL OF NEUROCHEMISTRY. 1988 NOV; 51 (5): 1394-1399

Date / Author / Journal

5221

THE PHARMACOLOGY OF SELEGILINE ((-)DEPRENYL) - NEW ASPECTS

ACTA NEUROLOGICA SCANDINAVICA. 1989; 80: 83-91

5222

6289 SCHJEIDE OA, GRIFFITHS TD, MORRISON LM

EFFECTS OF CHONDROITIN-4-SULFATE ON SURVIVAL, SIZES AND ULTRASTRUCTURES OF CULTURED WI-38 FIBROBLASTS AND FIBROBLASTS FROM PROGERIA PATIENTS

CYTOBIOS. 1989; 59 (236): 39-60

5223

6295 HILL MW, KARTHIGASAN J

GLUCOSE-METABOLISM AND PROTEIN-SYNTHESIS IN STRATIFIED SQUAMOUS EPITHELIA FROM YOUNG AND OLD MICE

EXPERIMENTAL GERONTOLOGY. 1989; 24 (4): 331-340

5224

6419 GILCHREST BA

SKIN AGING AND PHOTOAGING - AN OVERVIEW

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. 1989 SEP; 21 (3): 610-613

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5225

6507 PORTER MB, PEREIRASMITH OM, SMITH JR

NOVEL MONOCLONAL-ANTIBODIES IDENTIFY ANTIGENIC DETERMINANTS UNIQUE TO CELLULAR SENESCENCE

JOURNAL OF CELLULAR PHYSIOLOGY. 1990 FEB; 142 (2): 425-433

5226

6519 JAMASBI RJ, PERKINS EH

BIOLOGICAL HETEROGENEITY AND RADIATION SENSITIVITY OF INVITRO PROPAGATED LUNG METASTATIC LINES ORIGINATED FROM A TRANSPLANTABLE SQUAMOUS-CELL CARCINOMA OF BALB/C MOUSE

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY. 1990 MAR; 26 (3): 222-228

5227

6553 RIZZINO A, KAZAKOFF P, NEBELSICK J

DENSITY-INDUCED DOWN REGULATION OF EPIDERMAL GROWTH-FACTOR RECEPTORS

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY. 1990 MAY; 26 (5): 537-542

5228

6725 NING Y, PEREIRASMITH OM

MOLECULAR GENETIC APPROACHES TO THE STUDY OF CELLULAR SENESCENCE

MUTATION RESEARCH. 1991 MAR-NOV; 256 (2-6): 303-310

5229

6734 CHEN SC, CHOU CK, WONG FH, CHANG CM, HU CP

OVEREXPRESSION OF EPIDERMAL GROWTH-FACTOR AND INSULIN-LIKE GROWTH FACTOR-I RECEPTORS AND AUTOCRINE STIMULATION IN HUMAN ESOPHAGEAL- CARCINOMA CELLS

CANCER RESEARCH. 1991 APR 1; 51 (7): 1898-1903

5230

6897 PHILLIPS PD, PIGNOLO RJ, NISHIKURA K, CRISTOFALO VJ

RENEWED DNA-SYNTHESIS IN SENESCENT WI-38-CELLS BY EXPRESSION OF AN INDUCIBLE CHIMERIC C-FOS CONSTRUCT

JOURNAL OF CELLULAR PHYSIOLOGY. 1992 APR; 151 (1): 206-212

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5231

6907 HARRIS JR, PEDERSEN NL, MCCLEARN GE, PLOMIN R, NESSELROADE JR

AGE-DIFFERENCES IN GENETIC AND ENVIRONMENTAL-INFLUENCES FOR HEALTH FROM THE SWEDISH ADOPTION TWIN STUDY OF AGING

JOURNALS OF GERONTOLOGY. 1992 MAY; 47 (3): P213-P220

5232

6926 PIGNOLO RJ, MASORO EJ, NICHOLS WW, BRADT CI, CRISTOFALO VJ

SKIN FIBROBLASTS FROM AGED FISCHER-344 RATS UNDERGO SIMILAR CHANGES IN REPLICATIVE LIFE-SPAN BUT NOT IMMORTALIZATION WITH CALORIC RESTRICTION OF DONORS

EXPERIMENTAL CELL RESEARCH. 1992 JUL; 201 (1): 16-22

5233

7157 SUZUKI T, MIYAZAWA T, FUJIMOTO K, OTSUKA M, TSUTSUMI M

LIPIDS. 1993 AUG; 28 (8): 775-778

5234

7245 KONISHI I, FENDRICK JL, PARMLEY TH, QUIRK JG, OBRIEN TJ

EPIDERMAL GROWTH-FACTOR ENHANCES SECRETION OF THE OVARIAN TUMOR- ASSOCIATED CANCER ANTIGEN CA125 FROM THE HUMAN AMNION WISH CELL-LINE

JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION. 1994 JAN-MAR; 1 (1): 89-96

5235

7263 KILL IR, FARAGHER RGA, LAWRENCE K, SHALL S

THE EXPRESSION OF PROLIFERATION-DEPENDENT ANTIGENS DURING THE LIFE-SPAN OF NORMAL AND PROGEROID HUMAN FIBROBLASTS IN CULTURE

JOURNAL OF CELL SCIENCE. 1994 FEB; 107: 571-579

5236

7279 EFFROS RB, ZHU XM, WALFORD RL

STRESS-RESPONSE OF SENESCENT T-LYMPHOCYTES - REDUCED HSP70 IS INDEPENDENT OF THE PROLIFERATIVE BLOCK

JOURNALS OF GERONTOLOGY. 1994 MAR; 49 (2): B65-B70

5237

7309 TOKUMITSU M, KADOHAMA T, OGAWA K

INFREQUENT LOSS OF HETEROZYGOSITY AND MUTATION OF THE P53 GENE IN IMMORTAL AND TRANSFORMED MOUSE EMBRYO FIBROBLASTS

MOLECULAR CARCINOGENESIS. 1994 MAY; 10 (1): 52-57

5238

7312 LIU XT, STEWART CA, KING RL, DANNER DA, DELLORCO RT, et al.

PROHIBITIN EXPRESSION DURING CELLULAR SENESCENCE OF HUMAN-DIPLOID FIBROBLASTS

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1994 MAY 30; 201 (1): 409-414

5239

7321 SANDHU AK, HUBBARD K, KAUR GP, JHA KK, OZER HL, et al.

SENESCENCE OF IMMORTAL HUMAN FIBROBLASTS BY THE INTRODUCTION OF NORMAL HUMAN-CHROMOSOME-6

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1994 JUN 7; 91 (12): 5498-5502

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7337 IKRAM Z, NORTON T, JAT PS

THE BIOLOGICAL CLOCK THAT MEASURES THE MITOTIC LIFE-SPAN OF MOUSE EMBRYO FIBROBLASTS CONTINUES TO FUNCTION IN THE PRESENCE OF SIMIAN- VIRUS-40 LARGE TUMOR-ANTIGEN

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1994 JUL 5; 91 (14): 6448-6452

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7339 OHNEDA K, FUKUDA M, SHIMADA N, ISHIKAWA N, ICHOU T, et al.

INCREASED EXPRESSION OF NUCLEOSIDE DIPHOSPHATE KINASES NM23 IN HUMAN- DIPLOID FIBROBLASTS TRANSFORMED BY SV40 LARGE T-ANTIGEN OR CO-60 IRRADIATION

FEBS LETTERS. 1994 JUL 18; 348 (3): 273-277

5242

7363 HODGES DJ, LEE DC, SALTER CJ, REID DG, HARPER GP, et al.

PURIFICATION AND SECONDARY STRUCTURAL-ANALYSIS OF TISSUE INHIBITOR OF METALLOPROTEINASES-1

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY. 1994 SEP 21; 1208 (1): 94-100

5243

7460 KAUL SC, WADHWA R, MATSUDA Y, HENSLER PJ, PEREIRASMITH OM, et al.

MOUSE AND HUMAN CHROMOSOMAL ASSIGNMENTS OF MORTALIN, A NOVEL MEMBER OF THE MURINE HSP70 FAMILY OF PROTEINS

FEBS LETTERS. 1995 MAR 20; 361 (2-3): 269-272

5244

7465 SAITO H, HAMMOND AT, MOSES RE

THE EFFECT OF LOW-OXYGEN TENSION ON THE IN-VITRO REPLICATIVE LIFE-SPAN OF HUMAN-DIPLOID FIBROBLAST CELLS AND THEIR TRANSFORMED DERIVATIVES

EXPERIMENTAL CELL RESEARCH. 1995 APR; 217 (2): 272-279

5245

7561 ZWICKER J, LUCIBELLO FC, WOLFRAIM LA, GROSS C, TRUSS M, et al.

CELL-CYCLE REGULATION OF THE CYCLIN-A, CDC25C AND CDC2 GENES IS BASED ON A COMMON MECHANISM OF TRANSCRIPTIONAL REPRESSION

EMBO JOURNAL. 1995 SEP 15; 14 (18): 4514-4522

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7615 Kroll J

The ATPase module and the process of cellular immortalization

PHARMACOLOGICAL INTERVENTION IN AGING AND AGE-ASSOCIATED DISORDERS. 1996; 786: 57-61

5247

7638 Smith JR, Nakanishi M, Robetorye RS, Venable SF, PereiraSmith OM

Studies demonstrating the complexity of regulation and action of the growth inhibitory gene SDI1

EXPERIMENTAL GERONTOLOGY. 1996 JAN-APR; 31 (1-2): 327-335

5248

7722 Zahn RK, Jaud S, Schroder HC, ZahnDaimler G

DNA status in brain and heart as prominent co-determinant for life span? Assessing the different degrees of DNA damage, damage susceptibility, and repair capability in different organs of young and old mice

MECHANISMS OF AGEING AND DEVELOPMENT. 1996 AUG 15; 89 (2): 79-94

5249

7782 Tsushida T, Shinohara K

Evaluation of physiological functionalities of horticultural products using mammalian cell culture

JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI. 1997; 44 (9): 607-614

5250

7784 Kassem M, Ankersen L, Eriksen EF, Clark BFC, Rattan SIS

Demonstration of cellular aging and senescence in serially passaged long-term cultures of human trabecular osteoblasts

OSTEOPOROSIS INTERNATIONAL. 1997; 7 (6): 514-524

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7823 Haas C, Aicher WK, Dinkel A, Peter HH, Eibel H

Characterization of SV40T antigen immortalized human synovial fibroblasts: Maintained expression patterns of EGR-1, HLA-DR and some surface receptors

RHEUMATOLOGY INTERNATIONAL. 1997 MAR; 16 (6): 241-247

5252

7831 Higami Y, Shimokawa I, Okimoto T, Tomita M, Yuo T, et al.

Effect of aging and dietary restriction on hepatocyte proliferation and death in male F344 rats

CELL AND TISSUE RESEARCH. 1997 APR; 288 (1): 69-77

5253

7844 Zhang BX, Shih JWK, Wear DJ, Tsai S, Lo SC

High-level expression of H-ras and c-myc oncogenes in Mycoplasma- mediated malignant cell transformation

PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE. 1997 APR; 214 (4): 359-366

5254

7872 Chatelut M, Harzer K, Christomanou H, Feunteun J, Pieraggi MT, et al.

Model SV40-transformed fibroblast lines for metabolic studies of human prosaposin and acid ceramidase deficiencies

CLINICA CHIMICA ACTA. 1997 JUN 27; 262 (1-2): 61-76

5255

7890 Brown JP, Wei WY, Sedivy JM

Bypass of senescence after disruption of p21(CIP1/WAF1) gene in normal diploid human fibroblasts

SCIENCE. 1997 AUG 8; 277 (5327): 831-834

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Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus

ONCOGENE. 1997 OCT 16; 15 (16): 1911-1920

5257

8132 Savageau MA

Demand theory of gene regulation. II. Quantitative application to the lactose and maltose operons of Escherichia coli

GENETICS. 1998 AUG; 149 (4): 1677-1691

5258

8153 Suzuki M, Yang Z, Nakano K, Yatagai F, Suzuki K, et al.

Extension of in vitro life-span of gamma-irradiated human embryo cells accompanied by chromosome instability

JOURNAL OF RADIATION RESEARCH. 1998 SEP; 39 (3): 203-213

5259

8242 Fodil-Bourahla I, Drubaix I, Robert L

Effect of in vitro aging on the biosynthesis of glycosaminoglycans by human skin fibroblasts. Modulation by the elastin-laminin receptor

MECHANISMS OF AGEING AND DEVELOPMENT. 1999 JAN 15; 106 (3): 241-260

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8264 Vaziri H, Squire JA, Pandita TK, Bradley G, Kuba RM, et al.

Analysis of genomic integrity and p53-dependent G(1) checkpoint in telomerase-induced extended-life-span human fibroblasts

MOLECULAR AND CELLULAR BIOLOGY. 1999 MAR; 19 (3): 2373-2379

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5261

8297 Biecker E, Schachtschabel DO

Diminished stimulation of glycosaminoglycan synthesis of cultured human skin fibroblasts during in vitro aging by interleukin-1

ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE. 1999 APR; 32 (2): 124-130

5262

8298 Wei S, Wei WY, Sedivy JM

Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts

CANCER RESEARCH. 1999 APR 1; 59 (7): 1539-1543

5263

8326 Lewis K

Human longevity: an evolutionary approach

MECHANISMS OF AGEING AND DEVELOPMENT. 1999 JUN 1; 109 (1): 43-51

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8353 Waldo RH, Popham PL, Romero-Arroyo CE, Mothershed EA, Lee KK, et al.

Transcriptional analysis of the hmw gene cluster of Mycoplasma pneumoniae

JOURNAL OF BACTERIOLOGY. 1999 AUG; 181 (16): 4978-4985

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8404 Chung CY, Iida-Klein A, Wyatt LE, Rudkin GH, Ishida K, et al.

Serial passage of MC3T3-E1 cells alters osteoblastic function and responsiveness to transforming growth factor-beta 1 and bone morphogenetic protein-2

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999 NOV 11; 265 (1): 246-251

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8407 Feikin DR, Moroney JF, Talkington DF, Thacker WL, Code JE, et al.

An outbreak of acute respiratory disease caused by Mycoplasma pneumoniae and adenovirus at a federal service training academy: New implications from an old scenario

CLINICAL INFECTIOUS DISEASES. 1999 DEC; 29 (6): 1545-1550

5267

8408 Terman A, Dalen H, Brunk UT

Ceroid/lipofuscin-loaded human fibroblasts show decreased survival time and diminished autophagocytosis during amino acid starvation

EXPERIMENTAL GERONTOLOGY. 1999 DEC; 34 (8): 943-957

5268

8559 Waters DJ, Shen SR, Glickman LT

Life expectancy, antagonistic pleiotropy, and the testis of dogs and men

PROSTATE. 2000 JUN 1; 43 (4): 272-277

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8629 Sheng ZJ, Sun WP, Smith E, Cohen C, Sheng Z, et al.

Restoration of positioning control following Disabled-2 expression in ovarian and breast tumor cells

ONCOGENE. 2000 OCT 5; 19 (42): 4847-4854

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8670 Muravchick S

Gero-anesthesia: Functional reserve, cardiovascular changes, and postoperative complications

ANAESTHESIA PAIN INTENSIVE CARE AND EMERGENCY MEDICINE - APICE 15. 2001; : 555-567

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8766 Kim H, You SK, Kim IJ, Foster LK, Farris J, et al.

Alterations in p53 and E2F-1 function common to immortalized chicken embryo fibroblasts

ONCOGENE. 2001 MAY 10; 20 (21): 2671-2682

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8851 Adelfalk C, Lorenz M, Serra V, von Zglinicki T, Hirsch-Kauffmann M, et al.

Accelerated telomere shortening in Fanconi anemia fibroblasts - a longitudinal study

FEBS LETTERS. 2001 SEP 28; 506 (1): 22-26

5273

8889 Roske K, Blanchard A, Chambaud I, Citti C, Helbig JH, et al.

Phase variation among major surface antigens of Mycoplasma penetrans

INFECTION AND IMMUNITY. 2001 DEC; 69 (12): 7642-7651

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8990 Harvey SA, Jensen KO, Elmore LW, Holt SE

Pharmacological approaches to defining the role of chaperones in aging and prostate cancer progression

CELL STRESS & CHAPERONES. 2002 APR; 7 (2): 230-234

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9009 Joguchi A, Otsuka I, Minagawa S, Suzuki T, Fujii M, et al.

Overexpression of VDUP1 mRNA sensitizes HeLa cells to paraquat

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002 APR 26; 293 (1): 293-297

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9064 Badovinac VP, Porter BB, Harty JT

Programmed contraction of CD8(+) T cells after infection

NATURE IMMUNOLOGY. 2002 JUL; 3 (7): 619-626

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9127 Egorov EE, Terekhov SM, Vishnyakova KS, Karachentsev DN, El'darov MA, et al.

Immortalization of normal dermal fibroblasts of adult person via introduction of gene of catalytic subunit of telomerase

BIOLOGICHESKIE MEMBRANY. 2002 NOV-DEC; 19 (6): 483-490

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9311 Merker K, Ullrich O, Schmidt H, Sitte N, Grune T

Stability of the nuclear protein turnover during cellular senescence of human fibroblasts

FASEB JOURNAL. 2003 AUG; 17 (11): 1963-+

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9317 Evans RJ, Wyllie FS, Wynford-Thomas D, Kipling D, Jones CJ

A p53-dependent, telomere-independent proliferative life span barrier in human astrocytes consistent with the molecular genetics of glioma development

CANCER RESEARCH. 2003 AUG 15; 63 (16): 4854-4861

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9319 Kashino G, Kodama S, Nakayama Y, Suzuki K, Fukase K, et al.

Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells

FREE RADICAL BIOLOGY AND MEDICINE. 2003 AUG 15; 35 (4): 438-443

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9339 Yamamoto A, Kumakura S, Uchida M, Barrett JC, Tsutsui T

Immortalization of normal human embryonic fibroblasts by introduction of either the human papillomavirus type 16 E6 or E7 gene alone

INTERNATIONAL JOURNAL OF CANCER. 2003 SEP 1; 106 (3): 301-309

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9389 Balish MF, Ross SM, Fisseha M, Krause DC

Deletion analysis identifies key functional domains of the cytadherence-associated protein HMW2 of Mycoplasma pneumoniae

MOLECULAR MICROBIOLOGY. 2003 DEC; 50 (5): 1507-1516

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9470 Dillon BJ, Prieto VG, Curley SA, Ensor CM, Holtsberg FW, et al.

Incidence and distribution of argininosuccinate synthetase deficiency in human cancers - A method for identifying cancers sensitive to arginine deprivation

CANCER. 2004 FEB 15; 100 (4): 826-833

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9544 Holliday R

The multiple and irreversible causes of aging

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2004 JUN; 59 (6): 568-572

5285

9738 Terai M, Uyama T, Sugiki T, Li XK, Umezawa A, et al.

Immortalization of human fetal cells: The life span of umbilical cord blood-derived cells can be prolonged without manipulating p16(INK4a)/RB braking pathway

MOLECULAR BIOLOGY OF THE CELL. 2005 MAR; 16 (3): 1491-1499

5286

9797 Kitagawa J, Kanda K, Sugiura M, Tsuboi Y, Ogawa A, et al.

Effect of chronic inflammation on dorsal horn nociceptive neurons in aged rats

JOURNAL OF NEUROPHYSIOLOGY. 2005 JUN; 93 (6): 3594-3604

5287

9824 Hiyama K, Otani K, Ohtaki M, Satoh K, Kumazaki T, et al.

Differentially expressed genes throughout the cellular immortalization processes are quite different between normal human fibroblasts and endothelial cells

INTERNATIONAL JOURNAL OF ONCOLOGY. 2005 JUL; 27 (1): 87-95

5288

10030 Vesper BJ, Lee S, Hammer ND, Elseth KM, Barrett AGM, et al.

Developing a structure-function relationship for anionic porphyrazines exhibiting selective anti-tumor activity

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY. 2006 MAR 1; 82 (3): 180-186

5289

10061 Jin X, Lee JS, Kwak S, Jung JE, Kim TK, et al.

Myogenic differentiation of p53-and Rb-deficient immortalized and transformed bovine fibroblasts in response to myoD

MOLECULES AND CELLS. 2006 APR 30; 21 (2): 206-212

5290

10139 Mastromonaco GF, D Perrault S, Betts DH, King WA

Role of chromosome stability and telomere length in the production of viable cell lines for somatic cell nuclear transfer

BMC DEVELOPMENTAL BIOLOGY. 2006 AUG 9; 6: Art. No. 41

Date / Author / Journal

LCS

GCS

LCR

5291

10146 Muennig P, Lubetkin E, Jia HM, Franks P

Gender and the burden of disease attributable to obesity

AMERICAN JOURNAL OF PUBLIC HEALTH. 2006 SEP; 96 (9): 1662-1668

5292

10168 Sasaki T, Maier B, Bartke A, Scrable H

Progressive loss of SIRT1 with cell cycle withdrawal

AGING CELL. 2006 OCT; 5 (5): 413-422

5293

10427 Osanai M, Murata M, Nishikiori N, Chiba H, Kojima T, et al.

Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells

CANCER SCIENCE. 2007 JUL; 98 (7): 1027-1034

5294

10680 Bigot A, Jacquemin V, Debacq-Chainiaux F, Butler-Browne GS, Toussain O, et al.

Replicative aging down-regulates the myogenic regulatory factors in human myoblasts

BIOLOGY OF THE CELL. 2008 MAR; 100 (3): 189-199

5295

10721 Alig L, Alsenz J, Andjelkovic M, Bendels S, Bernardeau A, et al.

Benzodioxoles: Novel cannabinoid-1 receptor inverse Agonists for the treatment of obesity

JOURNAL OF MEDICINAL CHEMISTRY. 2008 APR 10; 51 (7): 2115-2127

5296

10739 Ilmonen P, Kotrschal A, Penn DJ

Telomere Attrition Due to Infection

PLOS ONE. 2008 MAY 14; 3 (5): Art. No. e2143

5297

10741 Lu T, Finkel T

Free radicals and senescence

EXPERIMENTAL CELL RESEARCH. 2008 MAY 15; 314 (9): 1918-1922

5298

10782 Patricio KP, Ribeiro H, Hoshino K, Bocchi SCM

The secret of longevity in the perception of the old-aged

CIENCIA & SAUDE COLETIVA. 2008 JUL-AUG; 13 (4): 1189-1198

5299

10958 Acevedo CA, Brown DI, Young ME, Reyes JG

Senescent Cultures of Human Dermal Fibroblasts Modified Phenotype When Immobilized in Fibrin Polymer

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION. 2009; 20 (13): 1929-1942

5300

11024 Hirschler V, Buzzano K, Erviti A, Ismael N, Silva S, et al.

Overweight and lifestyle behaviors of low socioeconomic elementary school children in Buenos Aires

BMC PEDIATRICS. 2009 FEB 24; 9: Art. No. 17

Hayflick w/citing papers Len Hayflick publications & the papers citing L Hayflick.	Historiographs	Glossary HistCite Guide About Grand Totals: LCS 84164, GCS 458115, CR 564869 Collection span: 1953 - 2011
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