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#	Date / Author / Journal	LCS	GCS	LCR	CR
2701	6824 SU CJ, DALLO SF, ALDERMAN H, BASEMAN JB DISTINCTIONS IN DNA AND PROTEIN PROFILES AMONG CLINICAL ISOLATES OF MYCOPLASMA-PNEUMONIAE JOURNAL OF GENERAL MICROBIOLOGY. 1991 DEC; 137: 2727-2732	1	8	10	34
2702	6846 ETHIER MF, MEDEIROS M, ROMANO FD, DOBSON JG MECHANISM OF ENHANCED CYCLIC-AMP STIMULATION BY ISOPROTERENOL IN AGED HUMAN FIBROBLASTS EXPERIMENTAL GERONTOLOGY. 1992; 27 (3): 287-300	1	5	10	23
2703	6944 MIKHELSON VM ON THE PRINCIPLE IMPOSSIBILITY OF A CONSIDERABLE PROLONGATION OF SPECIES LIFE-SPAN IN HUMAN IZVESTIYA AKADEMII NAUK SSSR SERIYA BIOLOGICHESKAYA. 1992 JUL-AUG; (4): 638-640	1	1	10	17
2704	6960 BANERJEE A, SRIVATSAN E, HASHIMOTO T, TAKAHASHI R, XU HJ, et al. IMMORTALIZATION OF FIBROBLASTS FROM 2 PATIENTS WITH HEREDITARY RETINOBLASTOMA ANTICANCER RESEARCH. 1992 SEP-OCT; 12 (5): 1347-1354	2	6	10	53
2705	7047 PAN JX, SHORT SR, GOFF SA, DICE JF UBIQUITIN POOLS, UBIQUITIN MESSENGER-RNA LEVELS, AND UBIQUITIN-MEDIATED PROTEOLYSIS IN AGING HUMAN FIBROBLASTS EXPERIMENTAL GERONTOLOGY. 1993 JAN-FEB; 28 (1): 39-49	4	22	10	42
2706	7048 TESCO G, VERGELLI M, AMADUCCI L, SORBI S GROWTH-PROPERTIES OF FAMILIAL ALZHEIMER SKIN FIBROBLASTS DURING INVITRO AGING EXPERIMENTAL GERONTOLOGY. 1993 JAN-FEB; 28 (1): 51-58	1	13	10	25
2707	7057 BARRETT JC NEOPLASTIC PROGRESSION OF SYRIAN-HAMSTER EMBRYO CELLS IN CULTURE PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE. 1993 JAN; 202 (1): 30-36	2	4	10	35
2708	7207 RANDERATH K, ZHOU GD, HART RW, TURTURRO A, RANDERATH E BIOMARKERS OF AGING - CORRELATION OF DNA I-COMPOUND LEVELS WITH MEDIAN LIFE-SPAN OF CALORICALLY RESTRICTED AND AD-LIBITUM FED RATS AND MICE MUTATION RESEARCH. 1993 DEC; 295 (4-6): 247-263	1	26	10	68
2709	7303 MIYAZAKI M, GOHDA E, MIHARA K, TSUBOI S, KAJI K, et al. INCREASE IN PRODUCTION OF HEPATOCYTE GROWTH-FACTOR BY HUMAN EMBRYONIC LUNG FIBROBLASTS IN THE PROCESS OF AGING IN CULTURE EXPERIMENTAL CELL RESEARCH. 1994 MAY; 212 (1): 22-29	2	11	10	66
2710	7323 STAMPS AC, DAVIES SC, BURMAN J, OHARE MJ ANALYSIS OF PROVIRAL INTEGRATION IN HUMAN MAMMARY EPITHELIAL-CELL LINES IMMORTALIZED BY RETROVIRAL INFECTION WITH A TEMPERATURE-SENSITIVE SV40 T-ANTIGEN CONSTRUCT INTERNATIONAL JOURNAL OF CANCER. 1994 JUN 15; 57 (6): 865-874	2	64	10	26
#	Date / Author / Journal	LCS	GCS	LCR	CR
2711	7329 ZHENG T DNA-DAMAGE AND THE PROLIFERATION AND AGING OF CELLS IN CULTURE - A MATHEMATICAL-MODEL WITH TIME-LAG MATHEMATICAL BIOSCIENCES. 1994 JUL; 122 (1): 67-88	1	1	10	12
2712	7392 VERTINO PM, ISSA JP, PEREIRASMITH OM, BAYLIN SB STABILIZATION OF DNA METHYLTRANSFERASE LEVELS AND CPG ISLAND HYPERMETHYLATION PRECEDE SV40-INDUCED IMMORTALIZATION OF HUMAN FIBROBLASTS CELL GROWTH & DIFFERENTIATION. 1994 DEC; 5 (12): 1395-1402	9	53	10	53
2713	7405 KAUL SC, WADHWA R, SUGIHARA T, OBUCHI K, KOMATSU Y, et al. IDENTIFICATION OF GENETIC EVENTS INVOLVED IN EARLY STEPS OF IMMORTALIZATION OF MOUSE FIBROBLASTS BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 1994 DEC 15; 1201 (3): 389-396	4	15	10	21
2714	7408 CHASTEL C LINKS AND INTERACTIONS BETWEEN MYCOPLASMAS AND VIRUSES - PAST CONFUSIONS AND PRESENT REALITIES ARCHIVES OF VIROLOGY. 1995; 140 (5): 811-826	0	4	10	104
2715	7449 ROSENBERGER RF THE INITIATION OF SENESCENCE AND ITS RELATIONSHIP TO EMBRYONIC-CELL DIFFERENTIATION BIOESSAYS. 1995 MAR; 17 (3): 257-260	2	6	10	37
2716	7510 NOBLE M, GROVES AK, ATALIOTIS P, IKRAM Z, JAT PS THE H-2K(B)TSA58 TRANSGENIC MOUSE - A NEW TOOL FOR THE RAPID GENERATION OF NOVEL CELL-LINES TRANSGENIC RESEARCH. 1995 JUL; 4 (4): 215-225	0	41	10	80
2717	7511 METZ T, HARRIS AW, ADAMS JM ABSENCE OF P53 ALLOWS DIRECT IMMORTALIZATION OF HEMATOPOIETIC-CELLS BY THE MYC AND RAF ONCOGENES CELL. 1995 JUL 14; 82 (1): 29-36	10	96	10	51
2718	7528 EDINGTON KG, LOUGHRAN OP, BERRY IJ, PARKINSON EK CELLULAR IMMORTALITY - A LATE EVENT IN THE PROGRESSION OF HUMAN SQUAMOUS-CELL CARCINOMA OF THE HEAD AND NECK ASSOCIATED WITH P53 ALTERATION AND A HIGH-FREQUENCY OF ALLELE LOSS MOLECULAR CARCINOGENESIS. 1995 AUG; 13 (4): 254-265	14	65	10	51
2719	7530 WRIGHT WE, SHAY JW TIME, TELOMERES AND TUMORS - IS CELLULAR SENESCENCE MORE THAN AN ANTICANCER MECHANISM TRENDS IN CELL BIOLOGY. 1995 AUG; 5 (8): 293-297	35	101	10	44
2720	7619 Holliday R Endless quest BIOESSAYS. 1996 JAN; 18 (1): 3-5	12	21	10	26
#	Date / Author / Journal	LCS	GCS	LCR	CR
2721	7717 Garfinkel S, Hu X, Prudovsky IA, McMahon GA, Kapnik EM, et al. FGF-1-dependent proliferative and migratory responses are impaired in senescent human umbilical vein endothelial cells and correlate with the inability to signal tyrosine phosphorylation of fibroblast growth factor receptor-1 substrates JOURNAL OF CELL BIOLOGY. 1996 AUG; 134 (3): 783-791	4	53	10	53
2722	7731 Good LF, Dimri GP, Campisi J, Chen KY Regulation of dihydrofolate reductase gene expression and E2F components in human diploid fibroblasts during growth and senescence JOURNAL OF CELLULAR PHYSIOLOGY. 1996 SEP; 168 (3): 580-588	13	29	10	44
2723	7746 Stio M, Lunghi B, Celli A, Nassi P, Treves C Effect of 1,25-dihydroxyvitamin D-3 on proliferation in senescent IMR- 90 human fibroblasts MECHANISMS OF AGEING AND DEVELOPMENT. 1996 OCT 4; 91 (1): 23-36	0	5	10	39
2724	7752 Olovnikov AM The molecular mechanism of morphogenesis: A theory of location DNA BIOCHEMISTRY-MOSCOW. 1996 NOV; 61 (11): 1383-1401	1	2	10	68
2725	7764 Rittling SR Clonal nature of spontaneously immortalized 3T3 cells EXPERIMENTAL CELL RESEARCH. 1996 NOV 25; 229 (1): 7-13	3	9	10	38
2726	7765 Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, et al. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996 NOV 26; 93 (24): 13742-13747	211	486	10	37
2727	7766 Solmi R, Tietz C, Zucchini C, Gualandi G, Pugnaloni A, et al. In vitro study of gingival fibroblasts from normal and inflamed tissue: Age-related responsiveness MECHANISMS OF AGEING AND DEVELOPMENT. 1996 NOV 29; 92 (1): 31-41	2	5	10	44
2728	7788 Johnson TE Genetic influences on aging EXPERIMENTAL GERONTOLOGY. 1997 JAN-APR; 32 (1-2): 11-22	5	22	10	91
2729	7812 Passi A, Albertini R, Campagnari F, DeLuca G Modifications of proteoglycans secreted into the growth medium by young and senescent human skin fibroblasts FEBS LETTERS. 1997 FEB 3; 402 (2-3): 286-290	1	10	10	30
2730	7817 Chen ZP, Chen KY Dramatic attenuation of hypusine formation on eukaryotic initiation factor 5A during senescence of IMR-90 human diploid fibroblasts JOURNAL OF CELLULAR PHYSIOLOGY. 1997 MAR; 170 (3): 248-254	0	8	10	42
#	Date / Author / Journal	LCS	GCS	LCR	CR
2731	7912 Mao ZB, Zhang ZY, Tong TJ Induction of c-fos/c-myc expression by epidermal growth factor decreases with alteration of their gene binding proteins in senescent fibroblasts CHINESE MEDICAL JOURNAL. 1997 OCT; 110 (10): 755-759	0	3	10	30
2732	8042 Petersen S, Saretzki G, von Zglinicki T Preferential accumulation of single-stranded regions in telomeres of human fibroblasts EXPERIMENTAL CELL RESEARCH. 1998 FEB 25; 239 (1): 152-160	55	165	10	33
2733	8044 Vaziri H, Benchimol S Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span CURRENT BIOLOGY. 1998 FEB 26; 8 (5): 279-282	223	646	10	24
2734	8046 Mori Y, Hatamochi A, Arakawa M, Ueki H Reduced expression of mRNA for transforming growth factor beta (TGF beta) and TGF beta receptors I and II and decreased TGF beta binding to the receptors in in vitro-aged fibroblasts ARCHIVES OF DERMATOLOGICAL RESEARCH. 1998 MAR; 290 (3): 158-162	4	14	10	32
2735	8047 Roberts RA Anti-ageing efficacy screening ATLA-ALTERNATIVES TO LABORATORY ANIMALS. 1998 MAR-APR; 26 (2): 249-254	0	1	10	29
2736	8083 Toussaint O, Schneider ED The thermodynamics and evolution of complexity in biological systems COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY. 1998 MAY; 120 (1): 3-9	0	25	10	31
2737	8096 Rubin H Telomerase and cellular lifespan: Ending the debate? NATURE BIOTECHNOLOGY. 1998 MAY; 16 (5): 396-397	16	27	10	22
2738	8143 Erickson S, Sangfelt O, Heyman M, Castro J, Einhorn S, et al. Involvement of the Ink4 proteins p16 and p15 in T-lymphocyte senescence ONCOGENE. 1998 AUG 6; 17 (5): 595-602	14	58	10	44
2739	8192 Tsao YP, Li SF, Liu JC, Chen SL Apoptosis is induced in aging SV40 T antigen-transformed human fibroblasts through p53- and p21(CIP1/WAF1)-independent pathways CANCER LETTERS. 1998 NOV 13; 133 (1): 77-82	1	5	10	18
2740	8256 Palmieri D, Watson JM, Rinehart CA Age-related expression of PEDF/EPC-1 in human endometrial stromal fibroblasts: Implications for interactive senescence EXPERIMENTAL CELL RESEARCH. 1999 FEB 25; 247 (1): 142-147	3	26	10	39
#	Date / Author / Journal	LCS	GCS	LCR	CR
2741	8279 Riabowol K Editorial: Biological aging research in Canada: Past, present and future CANADIAN JOURNAL ON AGING-REVUE CANADIENNE DU VIEILLISSEMENT. 1999 SPR; 18 (1): I-VII	0	1	10	22
2742	8296 Ahlert G Biogerontology: Present state and recent developments ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE. 1999 APR; 32 (2): 112-123	0	0	10	97
2743	8353 Waldo RH, Popham PL, Romero-Arroyo CE, Mothershed EA, Lee KK, et al. Transcriptional analysis of the hmw gene cluster of Mycoplasma pneumoniae JOURNAL OF BACTERIOLOGY. 1999 AUG; 181 (16): 4978-4985	2	15	10	36
2744	8362 Alani RM, Hasskarl J, Grace M, Hernandez HC, Israel MA, et al. Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999 AUG 17; 96 (17): 9637-9641	9	126	10	32
2745	8369 Martin GM, Oshima J, Gray MD, Poot M What geriatricians should know about the Werner syndrome JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 1999 SEP; 47 (9): 1136-1144	5	45	10	69
2746	8386 Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, et al. Inhibition of telomerase limits the growth of human cancer cells NATURE MEDICINE. 1999 OCT; 5 (10): 1164-1170	82	626	10	57
2747	8431 Matuoka K, Chen KY Possible role of subunit A of nuclear factor Y (NF-YA) in normal human diploid fibroblasts during senescence BIOGERONTOLOGY. 2000; 1 (3): 261-271	0	7	10	34
2748	8458 Kudravi SA, Reed MJ Aging, cancer, and wound healing IN VIVO. 2000 JAN-FEB; 14 (1): 83-92	1	11	10	113
2749	8483 Reed MJ, Corsa AC, Kudravi SA, McCormick RS, Arthur WT A deficit in collagenase activity contributes to impaired migration of aged microvascular endothelial cells JOURNAL OF CELLULAR BIOCHEMISTRY. 2000 FEB; 77 (1): 116-126	3	46	10	35
2750	8488 Tsuji T, Miyazaki M, Sakaguchi M, Inoue Y, Namba M A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000 FEB 5; 268 (1): 20-24	4	65	10	33
#	Date / Author / Journal	LCS	GCS	LCR	CR
2751	8513 Pereira-Smith OM, Bertram MJ Replicative senescence GENERATIONS-JOURNAL OF THE AMERICAN SOCIETY ON AGING. 2000 SPR; 24 (1): 43-47	1	2	10	17
2752	8572 Steinert S, Shay JW, Wright WE Transient expression of human telomerase extends the life span of normal human fibroblasts BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000 JUL 14; 273 (3): 1095-1098	24	74	10	21
2753	8582 Artandi SE, DePinho RA Mice without telomerase: what can they teach us about human cancer? NATURE MEDICINE. 2000 AUG; 6 (8): 852-855	18	84	10	40
2754	8612 Duesberg P, Rasnick D Aneuploidy, the somatic mutation that makes cancer a species of its own CELL MOTILITY AND THE CYTOSKELETON. 2000 OCT; 47 (2): 81-107	5	106	10	228
2755	8652 Sit KH Crisis periods and apoptotic commitment: Death imprints? CURRENT MEDICINAL CHEMISTRY. 2000 DEC; 7 (12): 1247-1254	0	0	10	80
2756	8660 Dannenberg JH, van Rossum A, Schuijff L, Riele HT Ablation of the Retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth- restricting conditions GENES & DEVELOPMENT. 2000 DEC 1; 14 (23): 3051-3064	26	223	10	90
2757	8664 Frasca D, Barattini P, Tocchi G, Guidi F, Scarpaci S, et al. Modulation of X-ray-induced damage recognition and repair in ageing human peripheral blood mononuclear cells by an interleukin-6-type cytokine MECHANISMS OF AGEING AND DEVELOPMENT. 2000 DEC 20; 121 (1-3): 5-19	0	4	10	45
2758	8668 Knight JA The biochemistry of aging ADVANCES IN CLINICAL CHEMISTRY, VOL 35. 2001; 35: 1-62	0	12	10	293
2759	8682 Cottliar ASH, Slavutsky IR Telomeres and telomerase activity. Their role in senescence and in neoplastic development MEDICINA-BUENOS AIRES. 2001; 61 (3): 335-342	0	1	10	75
2760	8705 Wood LD, Halvorsen TL, Dhar S, Baur JA, Pandita RK, et al. Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression ONCOGENE. 2001 JAN 18; 20 (3): 278-288	13	55	10	65
#	Date / Author / Journal	LCS	GCS	LCR	CR
2761	8766 Kim H, You SK, Kim IJ, Foster LK, Farris J, et al. Alterations in p53 and E2F-1 function common to immortalized chicken embryo fibroblasts ONCOGENE. 2001 MAY 10; 20 (21): 2671-2682	7	26	10	36
2762	8797 Chakravarthy MV, Spangenburg EE, Booth FW Culture in low levels of oxygen enhances in vitro proliferation potential of satellite cells from old skeletal muscles CELLULAR AND MOLECULAR LIFE SCIENCES. 2001 JUL; 58 (8): 1150-1158	1	26	10	39
2763	8806 Bonelli MA, Alfieri RR, Poli M, Petronini PG, Borghetti AF Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro EXPERIMENTAL CELL RESEARCH. 2001 JUL 15; 267 (2): 165-172	1	8	10	47
2764	8838 Chakravarthy MV, Fiorotto ML, Schwartz RJ, Booth FW Long-term insulin-like growth factor-I expression in skeletal muscles attenuates the enhanced in vitro proliferation ability of the resident satellite cells in transgenic mice MECHANISMS OF AGEING AND DEVELOPMENT. 2001 SEP; 122 (12): 1303-1320	0	16	10	43
2765	8858 Nishio K, Inoue A, Qiao SL, Kondo H, Mimura A Senescence and cytoskeleton: overproduction of vimentin induces senescent-like morphology in human fibroblasts HISTOCHEMISTRY AND CELL BIOLOGY. 2001 OCT; 116 (4): 321-327	13	23	10	26
2766	8865 Pearson M, Pelicci PG PML interaction with p53 and its role in apoptosis and replicative senescence ONCOGENE. 2001 OCT 29; 20 (49): 7250-7256	6	69	10	96
2767	8888 Wagner M, Hampel B, Hutter E, Pfister G, Krek W, et al. Metabolic stabilization of p27 in senescent fibroblasts correlates with reduced expression of the F-box protein Skp2 EXPERIMENTAL GERONTOLOGY. 2001 DEC; 37 (1): 41-55	9	20	10	59
2768	8906 Wang W, Wu JF, Zhang ZY, Tong TJ Characterization of regulatory elements on the promoter region of p16(INK4a) that contribute to overexpression of p16 in senescent fibroblasts JOURNAL OF BIOLOGICAL CHEMISTRY. 2001 DEC 28; 276 (52): 48655-48661	9	32	10	38
2769	8957 Walen KH The origin of transformed cells: studies of spontaneous and induced cell transformation in cell cultures from marsupials, a snail, and human amniocytes CANCER GENETICS AND CYTOGENETICS. 2002 FEB; 133 (1): 45-54	6	16	10	86
2770	8968 Venetsanakos E, Mirza A, Fanton C, Romanov SR, Tlsty T, et al. Induction of tubulogenesis in telomerase-immortalized human microvascular endothelial cells by glioblastoma cells EXPERIMENTAL CELL RESEARCH. 2002 FEB 1; 273 (1): 21-33	3	58	10	68
#	Date / Author / Journal	LCS	GCS	LCR	CR
2771	8969 Djelloul S, Tarunina M, Barnouin K, Mackay A, Jat PS Differential protein expression, DNA binding and interaction with SV40 large tumour antigen implicate the p63-family of proteins in replicative senescence ONCOGENE. 2002 FEB 7; 21 (7): 981-989	1	14	10	33
2772	8994 Takubo K, Izumiyama-Shimomura N, Honma N, Sawabe M, Arai T, et al. Telomere lengths are characteristic in each human individual EXPERIMENTAL GERONTOLOGY. 2002 APR; 37 (4): 523-531	22	90	10	33
2773	9022 Schmitt CA, Fridman JS, Yang M, Lee S, Baranov E, et al. A senescence program controlled by p53 and p16(INK4a) contributes to the outcome of cancer therapy CELL. 2002 MAY 3; 109 (3): 335-346	85	378	10	41
2774	9036 Knapowski J, Wieczorowska-Tobis K, Witowski J Pathophysiology of ageing JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. 2002 JUN; 53 (2): 135-146	2	15	10	44
2775	9053 Hahn WC Senescence, telomere shortening and telomere maintenance CANCER BIOLOGY & THERAPY. 2002 JUL-AUG; 1 (4): 398-400	1	4	10	21
2776	9105 Hutter E, Unterluggauer H, Uberall F, Schramek H, Jansen-Durr P Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress EXPERIMENTAL GERONTOLOGY. 2002 OCT-NOV; 37 (10-11): 1165-1174	20	34	10	32
2777	9106 Renault V, Thornell LE, Butler-Browne G, Mouly V Human skeletal muscle satellite cells: aging, oxidative stress and the mitotic clock EXPERIMENTAL GERONTOLOGY. 2002 OCT-NOV; 37 (10-11): 1229-1236	2	30	10	28
2778	9130 Warner HR Recent progress in understanding the relationships among aging, replicative senescence, cell turnover and cancer IN VIVO. 2002 NOV-DEC; 16 (6): 393-396	2	5	10	30
2779	9173 Dierick JF, Wenders F, Chainiaux F, Remacle J, Fisher AB, et al. Retrovirally mediated overexpression of peroxiredoxin VI increases the survival of WI-38 human diploid fibroblasts exposed to cytotoxic doses of tert-butylhydroperoxide and UVB BIOGERONTOLOGY. 2003; 4 (3): 125-131	1	11	10	29
2780	9194 Steidl U, Kronenwett R, Martin S, Haas R Molecular biology of hematopoietic stem cells VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 66. 2003; 66: 1-28	0	7	10	175
#	Date / Author / Journal	LCS	GCS	LCR	CR
2781	9200 Wick G, Berger P, Jansen-Durr P, Grubeck-Loebenstein B A Darwinian-evolutionary concept of age-related diseases EXPERIMENTAL GERONTOLOGY. 2003 JAN-FEB; 38 (1-2): 13-25	4	22	10	100
2782	9215 Anisimov VN Games with glass-beads for biologists or science for the day after tomorrow? BIOCHEMISTRY-MOSCOW. 2003 FEB; 68 (2): 242-246	0	1	10	47
2783	9253 Tombor B, Rundell K, Oltvai ZN Bcl-2 promotes premature senescence induced by oncogenic Ras BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003 APR 11; 303 (3): 800-807	8	18	10	35
2784	9279 Argyle D, Ellsmore V, Gault EA, Munro AF, Nasir L Equine telomeres and telomerase in cellular immortalisation and ageing MECHANISMS OF AGEING AND DEVELOPMENT. 2003 JUN; 124 (6): 759-764	7	19	10	40
2785	9302 Haussmann MF, Winkler DW, O'Reilly KM, Huntington CE, Nisbet ICT, et al. Telomeres shorten more slowly in long-lived birds and mammals than in short-lived ones PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES. 2003 JUL 7; 270 (1522): 1387-1392	17	65	10	52
2786	9315 Alexander K, Yang HS, Hinds PW pRb inactivation in senescent cells leads to an E2F-dependent apoptosis requiring p73 MOLECULAR CANCER RESEARCH. 2003 AUG; 1 (10): 716-728	3	9	10	52
2787	9380 Busuttil RA, Rubio M, Dolle MET, Campisi J, Vijg J Oxygen accelerates the accumulation of mutations during the senescence and immortalization of murine cells in culture AGING CELL. 2003 DEC; 2 (6): 287-294	14	68	10	32
2788	9387 Smolikov S, Krauskopf A The Rap1p-telomere complex does not determine the replicative capacity of telomerase-deficient yeast MOLECULAR AND CELLULAR BIOLOGY. 2003 DEC; 23 (23): 8729-8739	0	2	10	61
2789	9392 Robert L, Robert AM Aging, from basic research to pathological applications PATHOLOGIE BIOLOGIE. 2003 DEC; 51 (10): 543-549	2	2	10	53
2790	9464 Bose C, Bhuvaneswaran C, Udupa KB Altered mitogen-activated protein kinase signal transduction in human skin fibroblasts during in vitro aging: Differential expression of low- density lipoprotein receptor JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2004 FEB; 59 (2): 126-135	2	6	10	59
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2791	9469 Rowe-Rendleman C, Glickman RD Possible therapy for age-related macular degeneration using human telomerase BRAIN RESEARCH BULLETIN. 2004 FEB 15; 62 (6): 549-553	2	7	10	54
2792	9518 Miyata Y, Okada K, Fujimoto A, Hata K, Kagami H, et al. The effect of the long-term cultivation on telomere length and morphology of cultured epidermis JOURNAL OF DERMATOLOGICAL SCIENCE. 2004 MAY; 34 (3): 221-230	0	2	10	31
2793	9531 Benanti JA, Galloway DA The normal response to RAS - Senescence or transformation? CELL CYCLE. 2004 JUN; 3 (6): 715-717	2	12	10	27
2794	9555 Hutter E, Renner K, Pfister G, Stockl P, Jansen-Durr P, et al. Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts BIOCHEMICAL JOURNAL. 2004 JUN 15; 380: 919-928	12	54	10	50
2795	9575 Dufour E, Larsson NG Understanding aging: revealing order out of chaos BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. 2004 JUL 23; 1658 (1-2): 122-132	4	45	10	200
2796	9576 Zheng WJ, Wang HY, Xue LX, Zhang ZY, Tong TJ Regulation of cellular senescence and p16(INK4a) expression by Id1 and E47 proteins in human diploid fibroblast JOURNAL OF BIOLOGICAL CHEMISTRY. 2004 JUL 23; 279 (30): 31524-31532	6	37	10	48
2797	9646 Tsuji T, Aoshiba K, Nagai A Cigarette smoke induces senescence in alveolar epithelial cells AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2004 DEC; 31 (6): 643-649	5	32	10	35
2798	9651 Alberghina L, Vai M, Vanoni M Probing control mechanisms of cell cycle and ageing in budding yeast CURRENT GENOMICS. 2004 DEC; 5 (8): 615-627	0	3	10	146
2799	9695 Hasty P The impact of DNA damage, genetic mutation and cellular responses on cancer prevention, longevity and aging: observations in humans and mice MECHANISMS OF AGEING AND DEVELOPMENT. 2005 JAN; 126 (1): 71-77	1	12	10	59
2800	9704 Kaur GP, Reddy DE, Zimonjic DB, de Riel JK, Athwal RS Functional identification of a BAC clone from 16q24 carrying a senescence gene SEN16 for breast cancer cells ONCOGENE. 2005 JAN 6; 24 (1): 47-54	0	2	10	44

Date / Author / Journal

LCS

GCS

LCR

2701

6824 SU CJ, DALLO SF, ALDERMAN H, BASEMAN JB

DISTINCTIONS IN DNA AND PROTEIN PROFILES AMONG CLINICAL ISOLATES OF MYCOPLASMA-PNEUMONIAE

JOURNAL OF GENERAL MICROBIOLOGY. 1991 DEC; 137: 2727-2732

2702

6846 ETHIER MF, MEDEIROS M, ROMANO FD, DOBSON JG

MECHANISM OF ENHANCED CYCLIC-AMP STIMULATION BY ISOPROTERENOL IN AGED HUMAN FIBROBLASTS

EXPERIMENTAL GERONTOLOGY. 1992; 27 (3): 287-300

2703

6944 MIKHELSON VM

ON THE PRINCIPLE IMPOSSIBILITY OF A CONSIDERABLE PROLONGATION OF SPECIES LIFE-SPAN IN HUMAN

IZVESTIYA AKADEMII NAUK SSSR SERIYA BIOLOGICHESKAYA. 1992 JUL-AUG; (4): 638-640

2704

6960 BANERJEE A, SRIVATSAN E, HASHIMOTO T, TAKAHASHI R, XU HJ, et al.

IMMORTALIZATION OF FIBROBLASTS FROM 2 PATIENTS WITH HEREDITARY RETINOBLASTOMA

ANTICANCER RESEARCH. 1992 SEP-OCT; 12 (5): 1347-1354

2705

7047 PAN JX, SHORT SR, GOFF SA, DICE JF

UBIQUITIN POOLS, UBIQUITIN MESSENGER-RNA LEVELS, AND UBIQUITIN-MEDIATED PROTEOLYSIS IN AGING HUMAN FIBROBLASTS

EXPERIMENTAL GERONTOLOGY. 1993 JAN-FEB; 28 (1): 39-49

2706

7048 TESCO G, VERGELLI M, AMADUCCI L, SORBI S

GROWTH-PROPERTIES OF FAMILIAL ALZHEIMER SKIN FIBROBLASTS DURING INVITRO AGING

EXPERIMENTAL GERONTOLOGY. 1993 JAN-FEB; 28 (1): 51-58

2707

7057 BARRETT JC

NEOPLASTIC PROGRESSION OF SYRIAN-HAMSTER EMBRYO CELLS IN CULTURE

PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE. 1993 JAN; 202 (1): 30-36

2708

7207 RANDERATH K, ZHOU GD, HART RW, TURTURRO A, RANDERATH E

BIOMARKERS OF AGING - CORRELATION OF DNA I-COMPOUND LEVELS WITH MEDIAN LIFE-SPAN OF CALORICALLY RESTRICTED AND AD-LIBITUM FED RATS AND MICE

MUTATION RESEARCH. 1993 DEC; 295 (4-6): 247-263

2709

7303 MIYAZAKI M, GOHDA E, MIHARA K, TSUBOI S, KAJI K, et al.

INCREASE IN PRODUCTION OF HEPATOCYTE GROWTH-FACTOR BY HUMAN EMBRYONIC LUNG FIBROBLASTS IN THE PROCESS OF AGING IN CULTURE

EXPERIMENTAL CELL RESEARCH. 1994 MAY; 212 (1): 22-29

2710

7323 STAMPS AC, DAVIES SC, BURMAN J, OHARE MJ

ANALYSIS OF PROVIRAL INTEGRATION IN HUMAN MAMMARY EPITHELIAL-CELL LINES IMMORTALIZED BY RETROVIRAL INFECTION WITH A TEMPERATURE-SENSITIVE SV40 T-ANTIGEN CONSTRUCT

INTERNATIONAL JOURNAL OF CANCER. 1994 JUN 15; 57 (6): 865-874

Date / Author / Journal

2711

DNA-DAMAGE AND THE PROLIFERATION AND AGING OF CELLS IN CULTURE - A MATHEMATICAL-MODEL WITH TIME-LAG

MATHEMATICAL BIOSCIENCES. 1994 JUL; 122 (1): 67-88

2712

7392 VERTINO PM, ISSA JP, PEREIRASMITH OM, BAYLIN SB

STABILIZATION OF DNA METHYLTRANSFERASE LEVELS AND CPG ISLAND HYPERMETHYLATION PRECEDE SV40-INDUCED IMMORTALIZATION OF HUMAN FIBROBLASTS

CELL GROWTH & DIFFERENTIATION. 1994 DEC; 5 (12): 1395-1402

2713

7405 KAUL SC, WADHWA R, SUGIHARA T, OBUCHI K, KOMATSU Y, et al.

IDENTIFICATION OF GENETIC EVENTS INVOLVED IN EARLY STEPS OF IMMORTALIZATION OF MOUSE FIBROBLASTS

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 1994 DEC 15; 1201 (3): 389-396

2714

7408 CHASTEL C

LINKS AND INTERACTIONS BETWEEN MYCOPLASMAS AND VIRUSES - PAST CONFUSIONS AND PRESENT REALITIES

ARCHIVES OF VIROLOGY. 1995; 140 (5): 811-826

104

2715

7449 ROSENBERGER RF

THE INITIATION OF SENESCENCE AND ITS RELATIONSHIP TO EMBRYONIC-CELL DIFFERENTIATION

BIOESSAYS. 1995 MAR; 17 (3): 257-260

2716

7510 NOBLE M, GROVES AK, ATALIOTIS P, IKRAM Z, JAT PS

THE H-2K(B)TSA58 TRANSGENIC MOUSE - A NEW TOOL FOR THE RAPID GENERATION OF NOVEL CELL-LINES

TRANSGENIC RESEARCH. 1995 JUL; 4 (4): 215-225

2717

7511 METZ T, HARRIS AW, ADAMS JM

ABSENCE OF P53 ALLOWS DIRECT IMMORTALIZATION OF HEMATOPOIETIC-CELLS BY THE MYC AND RAF ONCOGENES

CELL. 1995 JUL 14; 82 (1): 29-36

2718

7528 EDINGTON KG, LOUGHRAN OP, BERRY IJ, PARKINSON EK

CELLULAR IMMORTALITY - A LATE EVENT IN THE PROGRESSION OF HUMAN SQUAMOUS-CELL CARCINOMA OF THE HEAD AND NECK ASSOCIATED WITH P53 ALTERATION AND A HIGH-FREQUENCY OF ALLELE LOSS

MOLECULAR CARCINOGENESIS. 1995 AUG; 13 (4): 254-265

2719

7530 WRIGHT WE, SHAY JW

TIME, TELOMERES AND TUMORS - IS CELLULAR SENESCENCE MORE THAN AN ANTICANCER MECHANISM

TRENDS IN CELL BIOLOGY. 1995 AUG; 5 (8): 293-297

101

2720

7619 Holliday R

Endless quest

BIOESSAYS. 1996 JAN; 18 (1): 3-5

Date / Author / Journal

LCS

GCS

LCR

2721

7717 Garfinkel S, Hu X, Prudovsky IA, McMahon GA, Kapnik EM, et al.

FGF-1-dependent proliferative and migratory responses are impaired in senescent human umbilical vein endothelial cells and correlate with the inability to signal tyrosine phosphorylation of fibroblast growth factor receptor-1 substrates

JOURNAL OF CELL BIOLOGY. 1996 AUG; 134 (3): 783-791

2722

7731 Good LF, Dimri GP, Campisi J, Chen KY

Regulation of dihydrofolate reductase gene expression and E2F components in human diploid fibroblasts during growth and senescence

JOURNAL OF CELLULAR PHYSIOLOGY. 1996 SEP; 168 (3): 580-588

2723

7746 Stio M, Lunghi B, Celli A, Nassi P, Treves C

Effect of 1,25-dihydroxyvitamin D-3 on proliferation in senescent IMR- 90 human fibroblasts

MECHANISMS OF AGEING AND DEVELOPMENT. 1996 OCT 4; 91 (1): 23-36

2724

7752 Olovnikov AM

The molecular mechanism of morphogenesis: A theory of location DNA

BIOCHEMISTRY-MOSCOW. 1996 NOV; 61 (11): 1383-1401

2725

7764 Rittling SR

Clonal nature of spontaneously immortalized 3T3 cells

EXPERIMENTAL CELL RESEARCH. 1996 NOV 25; 229 (1): 7-13

2726

7765 Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, et al.

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996 NOV 26; 93 (24): 13742-13747

211

486

2727

7766 Solmi R, Tietz C, Zucchini C, Gualandi G, Pugnaloni A, et al.

In vitro study of gingival fibroblasts from normal and inflamed tissue: Age-related responsiveness

MECHANISMS OF AGEING AND DEVELOPMENT. 1996 NOV 29; 92 (1): 31-41

2728

7788 Johnson TE

Genetic influences on aging

EXPERIMENTAL GERONTOLOGY. 1997 JAN-APR; 32 (1-2): 11-22

2729

7812 Passi A, Albertini R, Campagnari F, DeLuca G

Modifications of proteoglycans secreted into the growth medium by young and senescent human skin fibroblasts

FEBS LETTERS. 1997 FEB 3; 402 (2-3): 286-290

2730

7817 Chen ZP, Chen KY

Dramatic attenuation of hypusine formation on eukaryotic initiation factor 5A during senescence of IMR-90 human diploid fibroblasts

JOURNAL OF CELLULAR PHYSIOLOGY. 1997 MAR; 170 (3): 248-254

Date / Author / Journal

LCS

GCS

LCR

2731

7912 Mao ZB, Zhang ZY, Tong TJ

Induction of c-fos/c-myc expression by epidermal growth factor decreases with alteration of their gene binding proteins in senescent fibroblasts

CHINESE MEDICAL JOURNAL. 1997 OCT; 110 (10): 755-759

2732

8042 Petersen S, Saretzki G, von Zglinicki T

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

EXPERIMENTAL CELL RESEARCH. 1998 FEB 25; 239 (1): 152-160

165

2733

8044 Vaziri H, Benchimol S

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

CURRENT BIOLOGY. 1998 FEB 26; 8 (5): 279-282

223

646

2734

8046 Mori Y, Hatamochi A, Arakawa M, Ueki H

Reduced expression of mRNA for transforming growth factor beta (TGF beta) and TGF beta receptors I and II and decreased TGF beta binding to the receptors in in vitro-aged fibroblasts

ARCHIVES OF DERMATOLOGICAL RESEARCH. 1998 MAR; 290 (3): 158-162

2735

8047 Roberts RA

Anti-ageing efficacy screening

ATLA-ALTERNATIVES TO LABORATORY ANIMALS. 1998 MAR-APR; 26 (2): 249-254

2736

8083 Toussaint O, Schneider ED

The thermodynamics and evolution of complexity in biological systems

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY. 1998 MAY; 120 (1): 3-9

2737

8096 Rubin H

Telomerase and cellular lifespan: Ending the debate?

NATURE BIOTECHNOLOGY. 1998 MAY; 16 (5): 396-397

2738

8143 Erickson S, Sangfelt O, Heyman M, Castro J, Einhorn S, et al.

Involvement of the Ink4 proteins p16 and p15 in T-lymphocyte senescence

ONCOGENE. 1998 AUG 6; 17 (5): 595-602

2739

8192 Tsao YP, Li SF, Liu JC, Chen SL

Apoptosis is induced in aging SV40 T antigen-transformed human fibroblasts through p53- and p21(CIP1/WAF1)-independent pathways

CANCER LETTERS. 1998 NOV 13; 133 (1): 77-82

2740

8256 Palmieri D, Watson JM, Rinehart CA

EXPERIMENTAL CELL RESEARCH. 1999 FEB 25; 247 (1): 142-147

Date / Author / Journal

2741

Editorial: Biological aging research in Canada: Past, present and future

CANADIAN JOURNAL ON AGING-REVUE CANADIENNE DU VIEILLISSEMENT. 1999 SPR; 18 (1): I-VII

2742

8296 Ahlert G

Biogerontology: Present state and recent developments

ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE. 1999 APR; 32 (2): 112-123

2743

8353 Waldo RH, Popham PL, Romero-Arroyo CE, Mothershed EA, Lee KK, et al.

Transcriptional analysis of the hmw gene cluster of Mycoplasma pneumoniae

JOURNAL OF BACTERIOLOGY. 1999 AUG; 181 (16): 4978-4985

2744

8362 Alani RM, Hasskarl J, Grace M, Hernandez HC, Israel MA, et al.

Immortalization of primary human keratinocytes by the helix-loop-helix protein, Id-1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1999 AUG 17; 96 (17): 9637-9641

126

2745

8369 Martin GM, Oshima J, Gray MD, Poot M

What geriatricians should know about the Werner syndrome

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 1999 SEP; 47 (9): 1136-1144

2746

8386 Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, et al.

Inhibition of telomerase limits the growth of human cancer cells

NATURE MEDICINE. 1999 OCT; 5 (10): 1164-1170

626

2747

8431 Matuoka K, Chen KY

Possible role of subunit A of nuclear factor Y (NF-YA) in normal human diploid fibroblasts during senescence

BIOGERONTOLOGY. 2000; 1 (3): 261-271

2748

8458 Kudravi SA, Reed MJ

Aging, cancer, and wound healing

IN VIVO. 2000 JAN-FEB; 14 (1): 83-92

113

2749

8483 Reed MJ, Corsa AC, Kudravi SA, McCormick RS, Arthur WT

A deficit in collagenase activity contributes to impaired migration of aged microvascular endothelial cells

JOURNAL OF CELLULAR BIOCHEMISTRY. 2000 FEB; 77 (1): 116-126

2750

8488 Tsuji T, Miyazaki M, Sakaguchi M, Inoue Y, Namba M

A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000 FEB 5; 268 (1): 20-24

Date / Author / Journal

LCS

GCS

LCR

2751

8513 Pereira-Smith OM, Bertram MJ

Replicative senescence

GENERATIONS-JOURNAL OF THE AMERICAN SOCIETY ON AGING. 2000 SPR; 24 (1): 43-47

2752

8572 Steinert S, Shay JW, Wright WE

Transient expression of human telomerase extends the life span of normal human fibroblasts

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000 JUL 14; 273 (3): 1095-1098

2753

8582 Artandi SE, DePinho RA

Mice without telomerase: what can they teach us about human cancer?

NATURE MEDICINE. 2000 AUG; 6 (8): 852-855

2754

8612 Duesberg P, Rasnick D

Aneuploidy, the somatic mutation that makes cancer a species of its own

CELL MOTILITY AND THE CYTOSKELETON. 2000 OCT; 47 (2): 81-107

106

228

2755

8652 Sit KH

Crisis periods and apoptotic commitment: Death imprints?

CURRENT MEDICINAL CHEMISTRY. 2000 DEC; 7 (12): 1247-1254

2756

8660 Dannenberg JH, van Rossum A, Schuijff L, Riele HT

Ablation of the Retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth- restricting conditions

GENES & DEVELOPMENT. 2000 DEC 1; 14 (23): 3051-3064

223

2757

8664 Frasca D, Barattini P, Tocchi G, Guidi F, Scarpaci S, et al.

Modulation of X-ray-induced damage recognition and repair in ageing human peripheral blood mononuclear cells by an interleukin-6-type cytokine

MECHANISMS OF AGEING AND DEVELOPMENT. 2000 DEC 20; 121 (1-3): 5-19

2758

8668 Knight JA

The biochemistry of aging

ADVANCES IN CLINICAL CHEMISTRY, VOL 35. 2001; 35: 1-62

293

2759

8682 Cottliar ASH, Slavutsky IR

Telomeres and telomerase activity. Their role in senescence and in neoplastic development

MEDICINA-BUENOS AIRES. 2001; 61 (3): 335-342

2760

8705 Wood LD, Halvorsen TL, Dhar S, Baur JA, Pandita RK, et al.

Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression

ONCOGENE. 2001 JAN 18; 20 (3): 278-288

Date / Author / Journal

LCS

GCS

LCR

2761

8766 Kim H, You SK, Kim IJ, Foster LK, Farris J, et al.

Alterations in p53 and E2F-1 function common to immortalized chicken embryo fibroblasts

ONCOGENE. 2001 MAY 10; 20 (21): 2671-2682

2762

8797 Chakravarthy MV, Spangenburg EE, Booth FW

Culture in low levels of oxygen enhances in vitro proliferation potential of satellite cells from old skeletal muscles

CELLULAR AND MOLECULAR LIFE SCIENCES. 2001 JUL; 58 (8): 1150-1158

2763

8806 Bonelli MA, Alfieri RR, Poli M, Petronini PG, Borghetti AF

Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro

EXPERIMENTAL CELL RESEARCH. 2001 JUL 15; 267 (2): 165-172

2764

8838 Chakravarthy MV, Fiorotto ML, Schwartz RJ, Booth FW

Long-term insulin-like growth factor-I expression in skeletal muscles attenuates the enhanced in vitro proliferation ability of the resident satellite cells in transgenic mice

MECHANISMS OF AGEING AND DEVELOPMENT. 2001 SEP; 122 (12): 1303-1320

2765

8858 Nishio K, Inoue A, Qiao SL, Kondo H, Mimura A

Senescence and cytoskeleton: overproduction of vimentin induces senescent-like morphology in human fibroblasts

HISTOCHEMISTRY AND CELL BIOLOGY. 2001 OCT; 116 (4): 321-327

2766

8865 Pearson M, Pelicci PG

PML interaction with p53 and its role in apoptosis and replicative senescence

ONCOGENE. 2001 OCT 29; 20 (49): 7250-7256

2767

8888 Wagner M, Hampel B, Hutter E, Pfister G, Krek W, et al.

Metabolic stabilization of p27 in senescent fibroblasts correlates with reduced expression of the F-box protein Skp2

EXPERIMENTAL GERONTOLOGY. 2001 DEC; 37 (1): 41-55

2768

8906 Wang W, Wu JF, Zhang ZY, Tong TJ

Characterization of regulatory elements on the promoter region of p16(INK4a) that contribute to overexpression of p16 in senescent fibroblasts

JOURNAL OF BIOLOGICAL CHEMISTRY. 2001 DEC 28; 276 (52): 48655-48661

2769

8957 Walen KH

The origin of transformed cells: studies of spontaneous and induced cell transformation in cell cultures from marsupials, a snail, and human amniocytes

CANCER GENETICS AND CYTOGENETICS. 2002 FEB; 133 (1): 45-54

2770

8968 Venetsanakos E, Mirza A, Fanton C, Romanov SR, Tlsty T, et al.

Induction of tubulogenesis in telomerase-immortalized human microvascular endothelial cells by glioblastoma cells

EXPERIMENTAL CELL RESEARCH. 2002 FEB 1; 273 (1): 21-33

Date / Author / Journal

LCS

GCS

LCR

2771

8969 Djelloul S, Tarunina M, Barnouin K, Mackay A, Jat PS

Differential protein expression, DNA binding and interaction with SV40 large tumour antigen implicate the p63-family of proteins in replicative senescence

ONCOGENE. 2002 FEB 7; 21 (7): 981-989

2772

8994 Takubo K, Izumiyama-Shimomura N, Honma N, Sawabe M, Arai T, et al.

Telomere lengths are characteristic in each human individual

EXPERIMENTAL GERONTOLOGY. 2002 APR; 37 (4): 523-531

2773

9022 Schmitt CA, Fridman JS, Yang M, Lee S, Baranov E, et al.

A senescence program controlled by p53 and p16(INK4a) contributes to the outcome of cancer therapy

CELL. 2002 MAY 3; 109 (3): 335-346

378

2774

9036 Knapowski J, Wieczorowska-Tobis K, Witowski J

Pathophysiology of ageing

JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. 2002 JUN; 53 (2): 135-146

2775

9053 Hahn WC

Senescence, telomere shortening and telomere maintenance

CANCER BIOLOGY & THERAPY. 2002 JUL-AUG; 1 (4): 398-400

2776

9105 Hutter E, Unterluggauer H, Uberall F, Schramek H, Jansen-Durr P

Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress

EXPERIMENTAL GERONTOLOGY. 2002 OCT-NOV; 37 (10-11): 1165-1174

2777

9106 Renault V, Thornell LE, Butler-Browne G, Mouly V

Human skeletal muscle satellite cells: aging, oxidative stress and the mitotic clock

EXPERIMENTAL GERONTOLOGY. 2002 OCT-NOV; 37 (10-11): 1229-1236

2778

9130 Warner HR

Recent progress in understanding the relationships among aging, replicative senescence, cell turnover and cancer

IN VIVO. 2002 NOV-DEC; 16 (6): 393-396

2779

9173 Dierick JF, Wenders F, Chainiaux F, Remacle J, Fisher AB, et al.

Retrovirally mediated overexpression of peroxiredoxin VI increases the survival of WI-38 human diploid fibroblasts exposed to cytotoxic doses of tert-butylhydroperoxide and UVB

BIOGERONTOLOGY. 2003; 4 (3): 125-131

2780

9194 Steidl U, Kronenwett R, Martin S, Haas R

Molecular biology of hematopoietic stem cells

VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 66. 2003; 66: 1-28

175

Date / Author / Journal

LCS

GCS

LCR

2781

9200 Wick G, Berger P, Jansen-Durr P, Grubeck-Loebenstein B

A Darwinian-evolutionary concept of age-related diseases

EXPERIMENTAL GERONTOLOGY. 2003 JAN-FEB; 38 (1-2): 13-25

100

2782

9215 Anisimov VN

Games with glass-beads for biologists or science for the day after tomorrow?

BIOCHEMISTRY-MOSCOW. 2003 FEB; 68 (2): 242-246

2783

9253 Tombor B, Rundell K, Oltvai ZN

Bcl-2 promotes premature senescence induced by oncogenic Ras

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003 APR 11; 303 (3): 800-807

2784

9279 Argyle D, Ellsmore V, Gault EA, Munro AF, Nasir L

Equine telomeres and telomerase in cellular immortalisation and ageing

MECHANISMS OF AGEING AND DEVELOPMENT. 2003 JUN; 124 (6): 759-764

2785

9302 Haussmann MF, Winkler DW, O'Reilly KM, Huntington CE, Nisbet ICT, et al.

Telomeres shorten more slowly in long-lived birds and mammals than in short-lived ones

PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES. 2003 JUL 7; 270 (1522): 1387-1392

2786

9315 Alexander K, Yang HS, Hinds PW

pRb inactivation in senescent cells leads to an E2F-dependent apoptosis requiring p73

MOLECULAR CANCER RESEARCH. 2003 AUG; 1 (10): 716-728

2787

9380 Busuttil RA, Rubio M, Dolle MET, Campisi J, Vijg J

Oxygen accelerates the accumulation of mutations during the senescence and immortalization of murine cells in culture

AGING CELL. 2003 DEC; 2 (6): 287-294

2788

9387 Smolikov S, Krauskopf A

The Rap1p-telomere complex does not determine the replicative capacity of telomerase-deficient yeast

MOLECULAR AND CELLULAR BIOLOGY. 2003 DEC; 23 (23): 8729-8739

2789

9392 Robert L, Robert AM

Aging, from basic research to pathological applications

PATHOLOGIE BIOLOGIE. 2003 DEC; 51 (10): 543-549

2790

9464 Bose C, Bhuvaneswaran C, Udupa KB

Altered mitogen-activated protein kinase signal transduction in human skin fibroblasts during in vitro aging: Differential expression of low- density lipoprotein receptor

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2004 FEB; 59 (2): 126-135

Date / Author / Journal

LCS

GCS

LCR

2791

9469 Rowe-Rendleman C, Glickman RD

Possible therapy for age-related macular degeneration using human telomerase

BRAIN RESEARCH BULLETIN. 2004 FEB 15; 62 (6): 549-553

2792

9518 Miyata Y, Okada K, Fujimoto A, Hata K, Kagami H, et al.

The effect of the long-term cultivation on telomere length and morphology of cultured epidermis

JOURNAL OF DERMATOLOGICAL SCIENCE. 2004 MAY; 34 (3): 221-230

2793

9531 Benanti JA, Galloway DA

The normal response to RAS - Senescence or transformation?

CELL CYCLE. 2004 JUN; 3 (6): 715-717

2794

9555 Hutter E, Renner K, Pfister G, Stockl P, Jansen-Durr P, et al.

Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts

BIOCHEMICAL JOURNAL. 2004 JUN 15; 380: 919-928

2795

9575 Dufour E, Larsson NG

Understanding aging: revealing order out of chaos

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. 2004 JUL 23; 1658 (1-2): 122-132

200

2796

9576 Zheng WJ, Wang HY, Xue LX, Zhang ZY, Tong TJ

Regulation of cellular senescence and p16(INK4a) expression by Id1 and E47 proteins in human diploid fibroblast

JOURNAL OF BIOLOGICAL CHEMISTRY. 2004 JUL 23; 279 (30): 31524-31532

2797

9646 Tsuji T, Aoshiba K, Nagai A

Cigarette smoke induces senescence in alveolar epithelial cells

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2004 DEC; 31 (6): 643-649

2798

9651 Alberghina L, Vai M, Vanoni M

Probing control mechanisms of cell cycle and ageing in budding yeast

CURRENT GENOMICS. 2004 DEC; 5 (8): 615-627

146

2799

9695 Hasty P

The impact of DNA damage, genetic mutation and cellular responses on cancer prevention, longevity and aging: observations in humans and mice

MECHANISMS OF AGEING AND DEVELOPMENT. 2005 JAN; 126 (1): 71-77

2800

9704 Kaur GP, Reddy DE, Zimonjic DB, de Riel JK, Athwal RS

Functional identification of a BAC clone from 16q24 carrying a senescence gene SEN16 for breast cancer cells

ONCOGENE. 2005 JAN 6; 24 (1): 47-54

Hayflick w/citing papers Len Hayflick publications & the papers citing L Hayflick.	Historiographs	Glossary HistCite Guide About Grand Totals: LCS 84164, GCS 458115, CR 564869 Collection span: 1953 - 2011
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