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Nodes: 30, Links: 110
LCS >= 203; Min: 203, Max: 3801 (LCS scaled)

1. 21 HAYFLICK L, MOORHEAD PS

SERIAL CULTIVATION OF HUMAN DIPLOID CELL STRAINS

EXPERIMENTAL CELL RESEARCH. 1961; 25 (3): 585-&
LCR: 3 CR: 62 LCS: 3801 GCS: 3801 SCS:

2. 68 CHANOCK RM, HAYFLICK L, BARILE MF

GROWTH ON ARTIFICIAL MEDIUM OF AN AGENT ASSOCIATED WITH ATYPICAL PNEUMONIA AND ITS IDENTIFICATION AS A PPLO

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1962; 48 (1): 41-&
LCR: 0 CR: 19 LCS: 848 GCS: 847 SCS:

3. 131 TODARO GJ, GREEN H

QUANTITATIVE STUDIES OF GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

JOURNAL OF CELL BIOLOGY. 1963; 17 (2): 299-&
LCR: 1 CR: 31 LCS: 296 GCS: 2009 SCS:

4. 247 CLYDE WA

MYCOPLASMA SPECIES IDENTIFICATION BASED UPON GROWTH INHIBITION BY SPECIFIC ANTISERA

JOURNAL OF IMMUNOLOGY. 1964; 92 (6): 958-&
LCR: 4 CR: 22 LCS: 306 GCS: 818 SCS:

5. 323 HAYFLICK L, CHANOCK RM

MYCOPLASMA SPECIES OF MAN

BACTERIOLOGICAL REVIEWS. 1965; 29 (2): 185-&
LCR: 52 CR: 304 LCS: 215 GCS: 215 SCS:

6. 345 HAYFLICK L

LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

EXPERIMENTAL CELL RESEARCH. 1965; 37 (3): 614-&
LCR: 11 CR: 44 LCS: 3146 GCS: 3146 SCS:

7. 449 HAYFLICK L

TISSUE CULTURES AND MYCOPLASMAS

TEXAS REPORTS ON BIOLOGY AND MEDICINE. 1965; 23 (S): 285-&
LCR: 25 CR: 68 LCS: 967 GCS: 967 SCS:

8. 1459 MARTIN GM, SPRAGUE CA, EPSTEIN CJ

REPLICATIVE LIFE-SPAN OF CULTIVATED HUMAN CELLS - EFFECTS OF DONORS AGE, TISSUE, AND GENOTYPE

LABORATORY INVESTIGATION. 1970; 23 (1): 86-&
LCR: 14 CR: 40 LCS: 661 GCS: 962 SCS:

9. 1935 HOLLIDAY R, TARRANT GM

ALTERED ENZYMES IN AGING HUMAN FIBROBLASTS

NATURE. 1972; 238 (5358): 26-&
LCR: 7 CR: 28 LCS: 203 GCS: 372 SCS:

10. 2095 CRISTOFA.VJ, SHARF BB

CELLULAR SENESCENCE AND DNA-SYNTHESIS - THYMIDINE INCORPORATION AS A MEASURE OF POPULATION AGE IN HUMAN DIPLOID CELLS

EXPERIMENTAL CELL RESEARCH. 1973; 76 (2): 419-427
LCR: 12 CR: 28 LCS: 396 GCS: 504 SCS:

11. 2205 OLOVNIKO.AM

THEORY OF MARGINOTOMY - INCOMPLETE COPYING OF TEMPLATE MARGIN IN ENZYMIC-SYNTHESIS OF POLYNUCLEOTIDES AND BIOLOGICAL SIGNIFICANCE OF PHENOMENON

JOURNAL OF THEORETICAL BIOLOGY. 1973; 41 (1): 181-190
LCR: 4 CR: 16 LCS: 291 GCS: 793 SCS:

12. 2460 SMITH JR, HAYFLICK L

VARIATION IN LIFE-SPAN OF CLONES DERIVED FROM HUMAN DIPLOID CELL STRAINS

JOURNAL OF CELL BIOLOGY. 1974; 62 (1): 48-53
LCR: 13 CR: 18 LCS: 225 GCS: 225 SCS:

13. 3148 SCHNEIDER EL, MITSUI Y

RELATIONSHIP BETWEEN INVITRO CELLULAR AGING AND INVIVO HUMAN AGE

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1976; 73 (10): 3584-3588
LCR: 10 CR: 24 LCS: 372 GCS: 453 SCS:

14. 3303 FINCH CE, Hayflick L

Handbook of the Biology of Aging

HDB BIOLOGY AGING. 1977;
LCR: 0 CR: 0 LCS: 451 GCS: 451 SCS:

15. 4641 ROHME D

EVIDENCE FOR A RELATIONSHIP BETWEEN LONGEVITY OF MAMMALIAN-SPECIES AND LIFE SPANS OF NORMAL FIBROBLASTS INVITRO AND ERYTHROCYTES INVIVO

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES. 1981; 78 (8): 5009-5013
LCR: 20 CR: 38 LCS: 206 GCS: 262 SCS:

16. 6225 PEREIRASMITH OM, SMITH JR

GENETIC-ANALYSIS OF INDEFINITE DIVISION IN HUMAN-CELLS - IDENTIFICATION OF 4 COMPLEMENTATION GROUPS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1988 AUG; 85 (16): 6042-6046
LCR: 16 CR: 34 LCS: 209 GCS: 357 SCS:

17. 6502 SESHADRI T, CAMPISI J

REPRESSION OF C-FOS TRANSCRIPTION AND AN ALTERED GENETIC PROGRAM IN SENESCENT HUMAN-FIBROBLASTS

SCIENCE. 1990 JAN 12; 247 (4939): 205-209
LCR: 17 CR: 57 LCS: 237 GCS: 415 SCS:

18. 6564 HARLEY CB, FUTCHER AB, GREIDER CW

TELOMERES SHORTEN DURING AGING OF HUMAN FIBROBLASTS

NATURE. 1990 MAY 31; 345 (6274): 458-460
LCR: 6 CR: 33 LCS: 763 GCS: 2637 SCS:

19. 6612 GOLDSTEIN S

REPLICATIVE SENESCENCE - THE HUMAN FIBROBLAST COMES OF AGE

SCIENCE. 1990 SEP 7; 249 (4973): 1129-1133
LCR: 51 CR: 88 LCS: 348 GCS: 548 SCS:

20. 6723 HARLEY CB

TELOMERE LOSS - MITOTIC CLOCK OR GENETIC TIME BOMB

MUTATION RESEARCH. 1991 MAR-NOV; 256 (2-6): 271-282
LCR: 29 CR: 83 LCS: 245 GCS: 846 SCS:

21. 6904 COUNTER CM, AVILION AA, LEFEUVRE CE, STEWART NG, GREIDER CW, et al.

TELOMERE SHORTENING ASSOCIATED WITH CHROMOSOME INSTABILITY IS ARRESTED IN IMMORTAL CELLS WHICH EXPRESS TELOMERASE ACTIVITY

EMBO JOURNAL. 1992 MAY; 11 (5): 1921-1929
LCR: 17 CR: 57 LCS: 349 GCS: 1512 SCS:

22. 6997 ALLSOPP RC, VAZIRI H, PATTERSON C, GOLDSTEIN S, YOUNGLAI EV, et al.

TELOMERE LENGTH PREDICTS REPLICATIVE CAPACITY OF HUMAN FIBROBLASTS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1992 NOV 1; 89 (21): 10114-10118
LCR: 21 CR: 47 LCS: 413 GCS: 1322 SCS:

23. 7274 NODA A, NING Y, VENABLE SF, PEREIRASMITH OM, SMITH JR

CLONING OF SENESCENT CELL-DERIVED INHIBITORS OF DNA-SYNTHESIS USING AN EXPRESSION SCREEN

EXPERIMENTAL CELL RESEARCH. 1994 MAR; 211 (1): 90-98
LCR: 12 CR: 27 LCS: 270 GCS: 1262 SCS:

24. 7564 DIMRI GP, LEE XH, BASILE G, ACOSTA M, SCOTT C, et al.

A BIOMARKER THAT IDENTIFIES SENESCENT HUMAN-CELLS IN CULTURE AND IN AGING SKIN IN-VIVO

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995 SEP 26; 92 (20): 9363-9367
LCR: 14 CR: 31 LCS: 788 GCS: 2315 SCS:

25. 7765 Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, et al.

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996 NOV 26; 93 (24): 13742-13747
LCR: 10 CR: 37 LCS: 211 GCS: 486 SCS:

26. 7826 Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a)

CELL. 1997 MAR 7; 88 (5): 593-602
LCR: 19 CR: 73 LCS: 413 GCS: 1964 SCS:

27. 8027 Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, et al.

Extension of life-span by introduction of telomerase into normal human cells

SCIENCE. 1998 JAN 16; 279 (5349): 349-352
LCR: 28 CR: 62 LCS: 719 GCS: 2452 SCS:

28. 8044 Vaziri H, Benchimol S

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

CURRENT BIOLOGY. 1998 FEB 26; 8 (5): 279-282
LCR: 10 CR: 24 LCS: 223 GCS: 646 SCS:

29. 8190 Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, et al.

Both Rb/p16(INK4a) inactivation and telomerase activity are required to immortalize human epithelial cells

NATURE. 1998 NOV 5; 396 (6706): 84-88
LCR: 6 CR: 30 LCS: 219 GCS: 756 SCS:

30. 9745 Olshansky SJ, Passaro DJ, Hershow RC, Layden J, Carnes BA, et al.

A potential decline in life expectancy in the United States in the 21st century

NEW ENGLAND JOURNAL OF MEDICINE. 2005 MAR 17; 352 (11): 1138-1145
LCR: 2 CR: 65 LCS: 566 GCS: 566 SCS:

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