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Identification of c-MYC as a target of the APC pathway
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW
SCIENCE 281 (5382): 1509-1512 SEP 4 1998
and the papers citing it.
Nodes: 919
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#Cited
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Nodes / AuthorsGCSLCS
108 1998 SCIENCE 281(5382):1509-1512
He TC; Sparks AB; Rago C; Hermeking H; Zawel L; da Costa LT; Morin PJ; Vogelstein B; Kinzler KW
Identification of c-MYC as a target of the APC pathway
919918
21112 1999 NATURE 398(6726):422-426
Tetsu O; McCormick F
beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
698498
324237 2000 GENES & DEVELOPMENT 14(15):1837-1851
Polakis P
Wnt signaling and cancer
448140
4441 1999 CELL 99(3):335-345
He TC; Chan TA; Vogelstein B; Kinzler KW
PPAR delta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
351104
51135 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(10):5522-5527
Shtutman M; Zhurinsky J; Simcha I; Albanese C; D'Amico M; Pestell R; Ben-Ze'ev A
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
351229
61108 1999 MOLECULAR AND CELLULAR BIOLOGY 19(1):1-11
Dang CV
c-myc target genes involved in cell growth, apoptosis, and metabolism
30931
75236 2000 GENES & DEVELOPMENT 14(13):1553-1577
Goodman RH; Smolik S
CBP/p300 in cell growth, transformation, and development
2864
84302 2000 NATURE GENETICS 24(3):245-250
Satoh S; Daigo Y; Furukawa Y; Kato T; Miwa N; Nishiwaki T; Kawasoe T; Ishiguro H; Fujita M; Tokino T; Sasaki Y; Imaoka S; Murata M; Shimano T; Yamaoka Y; Nakamura Y
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
257122
9114 1999 ANNUAL REVIEW OF BIOCHEMISTRY 68():965-1014
Chan TO; Rittenhouse SE; Tsichlis PN
AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation
2421
1014 1998 CELL 95(5):605-614
Gat U; DasGupta R; Degenstein L; Fuchs E
De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
23971
11158 1999 CURRENT OPINION IN GENETICS & DEVELOPMENT 9(1):15-21
Polakis P
The oncogenic activation of beta-catenin
207100
121119 1999 ONCOGENE 18(18):2883-2891
Crawford HC; Fingleton BM; Rudolph-Owen LA; Goss KJH; Rubinfeld B; Polakis P; Matrisian LM
The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors
206146
131133 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(4):1603-1608
Mann B; Gelos M; Siedow A; Hanski ML; Gratchev A; Ilyas M; Bodmer WF; Moyer MP; Riecken EO; Buhr HJ; Hanski C
Target genes of beta-catenin-T cell-factor lymphoid-enhancer-factor signaling in human colorectal carcinomas
204147
141102 1999 JOURNAL OF THE NATIONAL CANCER INSTITUTE 91(11):916-932
Potter JD
Colorectal cancer: Molecules and populations
1936
1515196 2000 CELL 103(2):311-320
Bienz M; Clevers H
Linking colorectal cancer to Wnt signaling
19060
1611130 1999 ONCOGENE 18(55):7860-7872
Miller JR; Hocking AM; Brown JD; Moon RT
Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways
18935
174195 2000 CELL 100(1):143-155
Fuchs E; Segre JA
Stem cells: A new lease on life
1825
18722 1999 BIOESSAYS 21(12):1021-1030
Morin PJ
beta-catenin signaling and cancer
18173
19174 1999 GENES & DEVELOPMENT 13(5):505-510
Maniatis T
A ubiquitin ligase complex essential for the NF-kappa B, Wnt/Wingless, and Hedgehog signaling pathways
18015
201115 1999 NATURE GENETICS 23(4):387-388
Velculescu VE; Madden SL; Zhang L; Lash AE; Yu J; Rago C; Lal A; Wang CJ; Beaudry GA; Ciriello KM; Cook BP; Dufault MR; Ferguson AT; Gao YH; He TC; Hermeking H; Hiraldo SK; Hwang PM; Lopez MA; Luderer HF; Mathews B; Petroziello JM; Polyak K; Zawel L; Zhang W; Zhang XM; Zhou W; Haluska FG; Jen J; Sukumar S; Landes GM; Riggins GJ; Vogelstein B; Kinzler KW
Analysis of human transcriptomes
15911
212114 1999 NATURE GENETICS 21(4):410-413
Chan EF; Gat U; McNiff JM; Fuchs E
A common human skin tumour is caused by activating mutations in beta-catenin
15569
222120 1999 ONCOGENE 18(19):2967-2987
Prendergast GC
Mechanisms of apoptosis by c-Myc
1528
23137 1999 CANCER RESEARCH 59(21):5403-5407
Lal A; Lash AE; Altschul SF; Velculescu V; Zhang L; McLendon RE; Marra MA; Prange C; Morin PJ; Polyak K; Papadopoulos N; Vogelstein B; Kinzler KW; Strausberg RL; Riggins GJ
A public database for gene expression in human cancers
14412
24256 1999 CURRENT OPINION IN CELL BIOLOGY 11(2):233-240
Eastman Q; Grosschedl R
Regulation of LEF-1/TCF transcription factors by Wnt and other signals
14431
252121 1999 ONCOGENE 18(19):3004-3016
Nesbit CE; Tersak JM; Prochownik EV
MYC oncogenes and human neoplastic disease
1409
261511 2001 MOLECULAR CELL 7(3):673-682
Yu J; Zhang L; Hwang PM; Kinzler KW; Vogelstein B
PUMA induces the rapid apoptosis of colorectal cancer cells
1372
273139 1999 SCIENCE 285(5435):1923-1926
Roose J; Huls G; van Beest M; Moerer P; van der Horn K; Goldschmeding R; Logtenberg T; Cleavers H
Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1
12482
2817 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(25):14717-14722
Pennica D; Swanson TA; Welsh JW; Roy MA; Lawrence DA; Lee J; Brush J; Taneyhill LA; Deuel B; Lew M; Watanabe C; Cohen RL; Melhem MF; Finley GG; Quirke P; Goddard AD; Hillan KJ; Gurney AL; Botstein D; Levine AJ
WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors
12352
291138 1999 SCIENCE 283(5410):2089-2091
Seeling JM; Miller JR; Gil R; Moon RT; White R; Virshup DM
Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A
11744
3010390 2001 CELL 105(4):533-545
Huelsken J; Vogel R; Erdmann B; Cotsarelis G; Birchmeier W
beta-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
11020
31240 1999 CELL 98(6):779-790
Johnston LA; Prober DA; Edgar BA; Eisenman RN; Gallant P
Drosophila myc regulates cellular growth during development
1099
325301 2000 NATURE CELL BIOLOGY 2(9):653-660
Henderson BR
Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover
10939
332299 2000 NATURE 403(6771):781-785
Nishita M; Hashimoto MK; Ogata S; Laurent MN; Ueno N; Shibuya H; Cho KWY
Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer
10818
34131 1999 CANCER RESEARCH 59(4):826-830
Horikawa I; Cable PL; Afshari C; Barrett JJ
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene
1072
35413 1999 AMERICAN JOURNAL OF PATHOLOGY 155(4):1033-1038
Brabletz T; Jung A; Dag S; Hlubek F; Kirchner T
beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer
10466
36181 1999 HUMAN MOLECULAR GENETICS 8(10):1821-1832
Claverie JM
Computational methods for the identification of differential and coordinated gene expression
981
376513 2001 NATURE 411(6835):349-354
Taipale J; Beachy PA
The Hedgehog and Wnt signaling pathways in cancer
9811
381232 2000 GENES & DEVELOPMENT 14(3):272-277
Kung AL; Rebel VI; Bronson RT; Ch'ng LE; Sieff CA; Livingston DM; Yao TP
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
972
39130 1999 CANCER RESEARCH 59(2):269-273
Koch A; Denkhaus D; Albrecht S; Leuschner I; von Schweinitz D; Pietsch T
Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene
9544
4012 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 252(1):117-122
Sagara N; Toda G; Hirai M; Terada M; Katoh M
Molecular cloning, differential expression, and chromosomal localization of human Frizzled-1, Frizzled-2 and Frizzled-7
9411
411151 2000 ADVANCES IN CANCER RESEARCH, VOL 77 77():1-24
Barker N; Morin PJ; Clevers H
The yin-yang of TCF/beta-catenin signaling
9344
42110 1999 AMERICAN JOURNAL OF PATHOLOGY 154(4):965-973
Jankowski JA; Wright NA; Meltzer SJ; Triadafilopoulos G; Geboes K; Casson AG; Kerr D; Young LS
Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus
911
43132 1999 CANCER RESEARCH 59(8):1811-1815
Garcia-Rostan G; Tallini G; Herrero A; D'Aquila TG; Carcangiu ML; Rimm DL
Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma
900
442321 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(5):2229-2234
Hermeking H; Rago C; Schuhmacher M; Li Q; Barrett JF; Obaya AJ; O'Connell BC; Mateyak MK; Tam W; Kohlhuber F; Dang CV; Sedivy JM; Eick D; Vogelstein B; Kinzler KW
Identification of CDK4 as a target of c-MYC
8915
45134 1999 CANCER RESEARCH 59(12):2759-2765
Bieche I; Laurendeau I; Tozlu S; Olivi M; Vidaud D; Lidereau R; Vidaud M
Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay
887
46188 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(16):10681-10684
Yamamoto H; Kishida S; Kishida M; Ikeda S; Takada S; Kikuchi A
Phosphorylation of Axin, a Wnt signal negative regulator, by glycogen synthase kinase-3 beta regulates its stability
8740
475276 2000 JOURNAL OF CELL BIOLOGY 149(2):249-254
Takemaru KI; Moon RT
The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression
8543
484322 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(8):4262-4266
Lin SY; Xia WY; Wang JC; Kwong KY; Spohn B; Wen Y; Pestell RG; Hung MC
beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
8539
492512 2001 MOLECULAR CELL 7(5):915-926
Matsuzawa S; Reed JC
Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses
8420
501109 1999 MOLECULAR AND CELLULAR BIOLOGY 19(8):5576-5587
Gradl D; Kuhl M; Wedlich D
The Wnt/Wg signal transducer beta-catenin controls fibronectin expression
8349
512708 2002 JOURNAL OF THE NATIONAL CANCER INSTITUTE 94(4):252-266
Thun MJ; Henley SJ; Patrono C
Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues
831
521116 1999 ONCOGENE 18(4):849-854
Latres E; Chiaur DS; Pagano M
The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin
8122
53136 1999 CANCER RESEARCH 59(17):4213-4215
Duval A; Gayet J; Zhou XP; Iacopetta B; Thomas G; Hamelin R
Frequent frameshift mutations of the TCF-4 gene in colorectal cancers with microsatellite instability
7923
548230 2000 GASTROENTEROLOGY 119(3):854-865
Chung DC
The genetic basis of colorectal cancer: Insights into critical pathways of tumorigenesis
7810
55562 1999 DEVELOPMENT 126(20):4557-4568
DasGupta R; Fuchs E
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
7713
563428 2001 HUMAN MOLECULAR GENETICS 10(7):699-703
Nevins JR
The Rb/E2F pathway and cancer
772
57296 1999 JOURNAL OF CELL BIOLOGY 146(4):855-867
Orford K; Orford CC; Byers SW
Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest
7645
585391 2001 CELL 105(6):721-732
Dajani R; Fraser E; Roe SM; Young N; Good V; Dale TC; Pearl LH
Crystal structure of glycogen synthase kinase 3 beta: Structural basis for phosphate-primed substrate specificity and autoinhibition
756
5915235 2000 GENES & DEVELOPMENT 14(11):1319-1331
Kolligs FT; Kolligs B; Hajra KM; Hu G; Tani M; Cho KR; Fearon ER
gamma-Catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin
7441
60150 1999 CLINICAL CANCER RESEARCH 5(5):945-951
Meyskens FL; Gerner EW
Development of difluoromethylornithine (DFMO) as a chemoprevention agent
714
61290 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(25):18017-18025
Hecht A; Litterst CM; Huber O; Kemler R
Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro
7035
626416 2001 FASEB JOURNAL 15(12):2057-2072
Tegeder I; Pfeilschifter J; Geisslinger G
Cyclooxygenase-independent actions of cyclooxygenase inhibitors
700
6316166 2000 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1495(2):168-182
Seidensticker MJ; Behrens J
Biochemical interactions in the wnt pathway
6711
645233 2000 GENES & DEVELOPMENT 14(5):585-595
Xu LF; Corcoran RB; Welsh JW; Pennica D; Levine AJ
WISP-1 is a Wnt-1-and beta-catenin-responsive oncogene
6738
657438 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 18(5):991-996
Saitoh T; Hirai M; Katoh M
Molecular cloning and characterization of human Frizzled-8 gene on chromosome 10p11.2
677
66571 1999 EXPERIMENTAL CELL RESEARCH 253(1):63-77
Dang CV; Resar LMS; Emison E; Kim S; Li Q; Prescott JE; Wonsey D; Zeller K
Function of the c-Myc oncogenic transcription factor
662
67193 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(42):29583-29586
Fry CJ; Farnham PJ
Context-dependent transcriptional regulation
661
688441 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(1):111-115
Kirikoshi H; Sekihara H; Katoh M
Up-regulation of Frizzled-7 (FZD7) in human gastric cancer
663
69365 1999 EMBO JOURNAL 18(11):3054-3063
Damalas A; Ben-Ze'ev A; Simcha I; Shtutman N; Leal JFN; Zhurinsky J; Geiger B; Oren M
Excess beta-catenin promotes accumulation of transcriptionally active p53
6524
702543 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(3):992-999
Chen CR; Kang YB; Massague J
Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program
645
715110 1999 MOLECULAR AND CELLULAR BIOLOGY 19(8):5696-5706
Kolligs FT; Hu G; Dang CV; Fearon ER
Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression
6238
726440 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(1):105-110
Saitoh T; Hirai M; Katoh M
Molecular cloning and characterization of human Frizzled-5 gene on chromosome 2q33.3-q34 region
622
733303 2000 NATURE GENETICS 26(3):291-299
Jacobs JJL; Keblusek P; Robanus-Maandag E; Kristel P; Lingbeek M; Nederlof PM; van Welsem T; van de Vijver MJ; Koh EY; Daley GQ; van Lohuizen M
Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers
610
749347 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 284(5):1168-1175
Saitoh T; Hirai M; Katoh M
Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region
612
7523429 2001 HUMAN MOLECULAR GENETICS 10(7):721-733
Fearnhead NS; Britton MP; Bodmer WF
The ABC of APC
6112
763224 2000 EUROPEAN JOURNAL OF CANCER 36(5):664-674
Smith ML; Hawcroft G; Hull MA
The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action
604
776346 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 283(4):798-805
Kirikoshi H; Sekihara H; Katoh M
WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells
602
781132 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(1):139-144
Aoki M; Hecht A; Kruse U; Kemler R; Vogt PK
Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1
5927
799442 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 19(1):123-127
Saitoh T; Katoh M
Molecular cloning and characterization of human WNT8A
592
8013600 2002 CELL 111(2):241-250
van de Wetering M; Sancho E; Verweij C; de Lau W; Oving I; Hurlstone A; van der Horn K; Batlle E; Coudreuse D; Haramis AP; Tion-Pon-Fong M; Moerer P; van den Born M; Soete G; Pals S; Eilers M; Medema R; Clevers H
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
590
815275 2000 JOURNAL OF CELL BIOLOGY 148(3):567-578
Huelsken J; Vogel R; Brinkmann V; Erdmann B; Birchmeier C; Birchmeier W
Requirement for beta-catenin in anterior-posterior axis formation in mice
5814
823170 2000 BLOOD 96(6):2206-2214
Hashimoto S; Suzuki T; Nagai S; Yamashita T; Toyoda N; Matsushima K
Identification of genes specifically expressed in human activated and mature dendritic cells through serial analysis of gene expression
572
8329281 2000 JOURNAL OF CELL SCIENCE 113(18):3127-3139
Zhurinsky J; Shtutman M; Ben-Ze'ev A
Plakoglobin and beta-catenin: protein interactions, regulation and biological roles
5718
84261 1999 DEVELOPMENT 126(10):2285-2298
Zhu AJ; Watt FM
beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion
5620
851136 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(20):11566-11571
Jayachandra S; Low KG; Thlick AE; Yu J; Ling PD; Chang Y; Moore PS
Three unrelated viral transforming proteins (vIRF, EBNA2, and E1A) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors (Retracted article. See vol 98, pg 12313, 2001)
552
868515 2001 NATURE GENETICS 28(1):53-57
Hovanes K; Li TWH; Munguia JE; Truong T; Milovanovic T; Marsh JL; Holcombe RF; Waterman ML
beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer
5526
874345 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 281(3):815-820
Saitoh T; Moriwaki J; Koike J; Takagi A; Miwa T; Shiokawa K; Katoh M
Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway
544
88521 1999 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1424(2-3):M23-M37
Roose J; Clevers H
TCF transcription factors: molecular switches in carcinogenesis
530
893293 2000 MOLECULAR AND CELLULAR BIOLOGY 20(10):3497-3509
Santoni-Rugiu E; Falck J; Mailand N; Bartek J; Lukas J
Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway
530
903332 2000 TRENDS IN GENETICS 16(10):423-425
Velculescu VE; Vogelstein B; Kinzler KW
Analysing uncharted transcriptomes with SAGE
533
91168 1999 EUROPEAN JOURNAL OF CANCER 35(3):335-351
Ilyas M; Straub J; Tomlinson IPM; Bodmer WF
Genetic pathways in colorectal and other cancers
528
924267 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(31):23790-23797
Song DH; Sussman DJ; Seldin DC
Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells
518
9310284 2000 JOURNAL OF CLINICAL ONCOLOGY 18(9):1967-1979
Goss KH; Groden J
Biology of the adenomatous polyposis coli tumor suppressor
5015
9415327 2000 SEMINARS IN CANCER BIOLOGY 10(3):185-200
Buendia MA
Genetics of hepatocellular carcinoma
509
955406 2001 EMBO JOURNAL 20(17):4935-4943
Barker N; Hurlstone A; Musisi H; Miles A; Bienz M; Clevers H
The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation
5022
964162 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 269(1):103-109
Koike J; Sagara N; Kirikoshi H; Takagi A; Miwa T; Hirai M; Katoh M
Molecular cloning and genomic structure of the beta TRCP2 gene on chromosome 5q35.1
498
977180 2000 CANCER RESEARCH 60(13):3338-3342
Thompson WJ; Piazza GA; Li H; Liu L; Fetter J; Zhu B; Sperl G; Ahnen D; Pamukcu R
Exisulind induction of apoptosis involves guanosine 3 ',5 '-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin
493
985247 2000 IMMUNITY 13(1):15-24
Reya T; O'Riordan M; Okamura R; Devaney E; Willert K; Nusse R; Grosschedl R
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism
4911
992311 2000 ONCOGENE 19(8):1102-1113
Sternlicht MD; Bissell MJ; Werb Z
The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter
490
100142 1999 CELL 99(4):399-408
Kim L; Liu JC; Kimmel AR
The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification
486

#Cited
nodes
Nodes / AuthorsGCSLCS
10112172 2000 BRITISH JOURNAL OF SURGERY 87(8):992-1005
Wijnhoven BPL; Dinjens WNM; Pignatelli M
E-cadherin-catenin cell-cell adhesion complex and human cancer
485
102176 1999 GENOME RESEARCH 9(10):950-959
Ewing RM; Ben Kahla A; Poirot O; Lopez F; Audic S; Claverie JM
Large-scale statistical analyses of rice ESTs reveal correlated patterns of gene expression
470
103179 1999 HEPATOLOGY 29(4):1208-1214
Zimonjic DB; Keck CL; Thorgeirsson SS; Popescu NC
Novel recurrent genetic imbalances in human hepatocellular carcinoma cell lines identified by comparative genomic hybridization
471
1042191 2000 CARCINOGENESIS 21(3):469-476
Bach SP; Renehan AG; Potten CS
Stem cells: the intestinal stem cell as a paradigm
472
10510468 2001 JOURNAL OF CELL BIOLOGY 153(5):1049-1059
Gottardi CJ; Wong E; Gumbiner BM
E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner
4713
1062113 1999 NATURE CELL BIOLOGY 1(3):144-151
Yu X; Waltzer L; Bienz M
A new Drosophila APC homologue associated with adhesive zones of epithelial cells
4613
1072300 2000 NATURE 406(6798):897-902
Sasaki T; Irie-Sasaki J; Horie Y; Bachmaier K; Fata JE; Li M; Suzuki A; Bouchard D; Ho A; Redston M; Gallinger S; Khokha R; Mak TW; Hawkins PT; Stephens L; Scherer SW; Tsao M; Penninger JM
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)K gamma
464
1085309 2000 ONCOGENE 19(4):537-545
Ikeda S; Kishida M; Matsuura Y; Usui H; Kikuchi A
GSK-3 beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin
4621
1095437 2001 INTERNATIONAL JOURNAL OF ONCOLOGY 18(5):959-964
Saitoh T; Katoh M
Expression profiles of beta TRCP1 and beta TRCP2, and mutation analysis of beta TRCP2 in gastric cancer
466
11016518 2001 NATURE REVIEWS CANCER 1(1):55-67
Fodde R; Smits R; Clevers H
APC, signal transduction and genetic instability in colorectal cancer
465
11116168 2000 BIOESSAYS 22(11):961-965
Barker N; Clevers H
Catenins, Wnt signaling and cancer
4520
11213206 2000 COLORECTAL CANCER: NEW ASPECTS OF MOLECULAR BIOLOGY AND IMMUNOLOGY AND THEIR CLINICAL APPLICATIONS 910():21-35
Behrens J
Control of beta-catenin signaling in tumor development
4512
1137262 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(23):17894-17899
Chen RH; Ding WV; McCormick F
Wnt signaling to beta-catenin involves two interactive components - Glycogen synthase kinase-3 beta inhibition and activation of protein kinase C
4512
1143544 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(5):2598-2603
Park BH; Vogelstein B; Kinzler KW
Genetic disruption of PPAR delta decreases the tumorigenicity of human colon cancer cells
453
1154213 2000 DEVELOPMENT 127(3):469-482
Galceran J; Miyashita-Lin EM; Devaney E; Rubenstein JLR; Grosschedl R
Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1
443
1166278 2000 JOURNAL OF CELL BIOLOGY 149(4):761-766
Tirnauer JS; Bierer BE
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beta-catenin (Ctnnb1) gene mutations in diethylnitrosamine (DEN)-induced liver tumors in male F344 rats
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Protein kinase CK2: Signaling and tumorigenesis in the mammary gland
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beta-Catenin and the morphogenesis of colorectal cancer
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447116 1999 ANTICANCER RESEARCH 19(6A):4715-4728
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Tumor suppressor genes (TSG)
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448319 1999 BIOCHEMICAL JOURNAL 344():565-570
Baulida J; Batlle E; de Herreros AG
Adenomatous polyposis coil protein (APC)-independent regulation of beta-catenin/Tcf-4 mediated transcription in intestinal cells
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449123 1999 BRITISH JOURNAL OF CANCER 81(7):1116-1121
Park KS; Kim NG; Kim JJ; Kim H; Ahn YH; Choi KY
Differential regulation of MAP kinase cascade in human colorectal tumorigenesis
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450166 1999 ENDOCRINE 10(1):67-76
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Negative regulation of N-cadherin-mediated cell-cell adhesion by the estrogen receptor signaling pathway in rat pituitary GH(3) cells
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4511101 1999 JOURNAL OF INVESTIGATIVE DERMATOLOGY 113(2):258-262
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erbB-2 overexpression but no activation of beta-catenin gene in extramammary Paget's disease
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4521150 1999 WORLD JOURNAL OF GASTROENTEROLOGY 5(5):451-454
Zhang J; Lai MD; Chen J
Methylation status of p16 gene in colorectal carcinoma and normal colonic mucosa
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4534164 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 276(3):1162-1169
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Domains of Axin and disheveled required for interaction and function in Wnt signaling
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Apoptosis-related genes expressed in cardiovascular development and disease: an EST approach
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4551254 2000 INTERNATIONAL JOURNAL OF CANCER 90(4):175-185
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Survival of colorectal cancer cell lines treated with paclitaxel, radiation, and 5-FU: Effect of TP53 or hMLH1 deficiency
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4563256 2000 JAPANESE JOURNAL OF CANCER RESEARCH 91(6):597-603
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Isolation and characterization of human NBL4, a gene involved in the beta-catenin/Tcf signaling pathway
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4571263 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275(24):18470-18475
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Role of the adenomatous polyposis coli gene product in human cardiac development and disease
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Cytoplasmic beta-catenin accumulation as a predictor of hematogenous metastasis in human colorectal cancer
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4596331 2000 TOXICOLOGY LETTERS 112():403-409
Paulsen JE
Modulation by dietary factors in murine FAP models
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4601339 2001 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 281(5):G1279-G1289
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Dominant-negative TAK1 induces c-Myc and G(0) exit in liver
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4611363 2001 CANCER RESEARCH 61(4):1386-1391
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Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: Mediation through cyclooxygenase-independent pathways
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46213366 2001 CANCER RESEARCH 61(5):2097-2104
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Stabilized beta-catenin immortalizes colonic epithelial cells
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Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid
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Different patterns of beta-catenin expression in gastric carcinomas: relationship with clinicopathological parameters and prognostic outcome
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Recruitment of beta-catenin to cadherin-mediated intercellular adhesions is involved in myogenic induction
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Upstream stimulating factor-1 (USF1) and USF2 bind to and activate the promoter of the Adenomatous polyposis coli (APC) tumor suppressor gene
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Cadherins in neural crest cell development and transformation
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4685483 2001 JOURNAL OF PATHOLOGY 193(4):427-432
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The Hedgehog signalling pathway and cancer
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beta-catenin nuclear expression correlates with cyclin D1 overexpression in sporadic desmoid tumours
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4706497 2001 MODERN PATHOLOGY 14(9):900-905
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Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas
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Regulation of endothelial barrier function and growth by VE-cadherin, plakoglobin, and beta-catenin
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Pathway-specific tumor suppression: Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice
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Serial analysis of gene expression - Technical considerations and applications to cardiovascular biology
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Regulated expression of Wnts and frizzleds at specific stages of follicular development in the rodent ovary
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ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu Transgenic carcinomas
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Signalling networks that cause cancer
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Epidermal stem cells as targets for gene transfer
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Down-regulation of drs mRNA in human colon adenocarcinomas
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Sequence-specific high mobility group box factors recognize 10-12-base pair minor groove motifs
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Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium
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Altered expression of beta-catenin and c-erbB-2 in early gastric cancer
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Endothelial adherens junctions
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COX-2 inhibition and prevention of cancer
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p21(WAF1/cip1) is an important determinant of intestinal cell response to sulindac in vitro and in vivo
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4927383 2001 CANCER RESEARCH 61(22):8085-8088
Hao XP; Pretlow TG; Rao JS; Pretlow TP
beta-catenin expression is altered in human colonic aberrant crypt foci
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4933388 2001 CARCINOGENESIS 22(11):1885-1890
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Predominant mutation of codon 41 of the beta-catenin proto-oncogene in rat colon tumors induced by 1,2-dimethylhydrazine using a complete carcinogenic protocol
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4941423 2001 GUT 48(5):660-666
Brown WA; Skinner SA; Malcontenti-Wilson C; Vogiagis D; O'Brien PE
Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation
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4958461 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(49):45833-45839
Galea MA; Eleftheriou A; Henderson BR
ARM domain-dependent nuclear import of adenomatous polyposis coli protein is stimulated by the B56 alpha subunit of protein phosphatase 2A
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4961495 2001 MODERN PATHOLOGY 14(1):29-39
Aust DE; Terdiman TP; Willenbucher RF; Chew K; Ferrell L; Florendo C; Molinaro-Clark A; Baretton GB; Lohrs U; Waldman FM
Altered distribution of beta-catenin, and its binding proteins E-cadherin and APC, in ulcerative colitis-related colorectal cancers
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49710508 2001 MOLECULAR CARCINOGENESIS 31(1):56-62
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Wingless-type frizzled protein receptor signaling and its putative role in human colon cancer
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4985509 2001 MOLECULAR CARCINOGENESIS 31(2):68-73
Devereux TR; Stern MC; Flake GP; Yu MC; Zhang ZQ; London SJ; Taylor JA
CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1
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4994527 2001 ONCOGENE 20(30):4007-4018
Shi YJ; Simmons MN; Seki T; Oh SP; Sugrue SP
Change in gene expression subsequent to induction of Pnn/DRS/memA: increase in p21(cip1/waf1)
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Miwa N; Furuse M; Tsukita S; Niikawa N; Nakamura Y; Furukawa Y
Involvement of claudin-1 in the beta-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers
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