| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 1 | 1 | 1 1998 AMERICAN JOURNAL OF HUMAN GENETICS 63(6):1588-1593
Semb H; Christofori G
The tumor-suppressor function of E-cadherin | 20 | 3
|
| 2 | 1 | 2 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 252(1):117-122
Sagara N; Toda G; Hirai M; Terada M; Katoh M
Molecular cloning, differential expression, and chromosomal localization of human Frizzled-1, Frizzled-2 and Frizzled-7 | 94 | 11
|
| 3 | 1 | 3 1998 BULLETIN DU CANCER 85(11):925-928
Jeanteur P
The role of APC in colon cancer: zeroing in on MYC | 6 | 2
|
| 4 | 1 | 4 1998 CELL 95(5):605-614
Gat U; DasGupta R; Degenstein L; Fuchs E
De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin | 239 | 71
|
| 5 | 1 | 5 1998 CURRENT OPINION IN CELL BIOLOGY 10(6):702-709
Stappenbeck TS; Wong MH; Saam JR; Mysorekar IU; Gordon JI
Notes from some crypt watchers: regulation of renewal in the mouse intestinal epithelium | 28 | 3
|
| 6 | 1 | 6 1998 GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE 22(12):1071-1080
Jais P; Laurent-Puig P; Olschwang S
APC protein: protein interactions and cellular functions | 0 | 0
|
| 7 | 1 | 7 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(25):14717-14722
Pennica D; Swanson TA; Welsh JW; Roy MA; Lawrence DA; Lee J; Brush J; Taneyhill LA; Deuel B; Lew M; Watanabe C; Cohen RL; Melhem MF; Finley GG; Quirke P; Goddard AD; Hillan KJ; Gurney AL; Botstein D; Levine AJ
WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors | 123 | 52
|
| 8 | 0 | 8 1998 SCIENCE 281(5382):1509-1512
He TC; Sparks AB; Rago C; Hermeking H; Zawel L; da Costa LT; Morin PJ; Vogelstein B; Kinzler KW
Identification of c-MYC as a target of the APC pathway | 919 | 918
|
| 9 | 1 | 9 1999 AMERICAN JOURNAL OF PATHOLOGY 154(2):515-523
Wielenga VJM; Smits R; Korinek V; Smit L; Kielman M; Fodde R; Clevers H; Pals ST
Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway | 37 | 21
|
| 10 | 1 | 10 1999 AMERICAN JOURNAL OF PATHOLOGY 154(4):965-973
Jankowski JA; Wright NA; Meltzer SJ; Triadafilopoulos G; Geboes K; Casson AG; Kerr D; Young LS
Molecular evolution of the metaplasia-dysplasia-adenocarcinoma sequence in the esophagus | 91 | 1
|
| 11 | 4 | 11 1999 AMERICAN JOURNAL OF PATHOLOGY 155(3):703-710
Van Nhieu JT; Renard CA; Wei Y; Cherqui D; Zafrani ES; Buendia MA
Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation | 20 | 0
|
| 12 | 1 | 12 1999 AMERICAN JOURNAL OF PATHOLOGY 155(4):1027-1032
Sarbia M; Loberg C; Wolter M; Arjumand J; Heep H; Reifenberger G; Gabbert HE
Expression of Bcl-2 and amplification of c-myc are frequent in basaloid squamous cell carcinomas of the esophagus | 10 | 2
|
| 13 | 4 | 13 1999 AMERICAN JOURNAL OF PATHOLOGY 155(4):1033-1038
Brabletz T; Jung A; Dag S; Hlubek F; Kirchner T
beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer | 104 | 66
|
| 14 | 1 | 14 1999 ANNUAL REVIEW OF BIOCHEMISTRY 68():965-1014
Chan TO; Rittenhouse SE; Tsichlis PN
AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation | 242 | 1
|
| 15 | 1 | 15 1999 ANTICANCER MOLECULES: STRUCTURE, FUNCTION, AND DESIGN 886():37-47
Ben-Ze'Ev A
The dual role of cytoskeletal anchor proteins in cell adhesion and signal transduction | 9 | 0
|
| 16 | 1 | 16 1999 ANTICANCER RESEARCH 19(6A):4715-4728
Teh BT; Larsson C; Nordenskjold M
Tumor suppressor genes (TSG) | 7 | 0
|
| 17 | 1 | 17 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 256(3):584-590
Omer CA; Miller PJ; Diehl RE; Kral AM
Identification of Tcf4 residues involved in high-affinity beta-catenin binding | 16 | 5
|
| 18 | 2 | 18 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 263(2):384-388
Wright M; Aikawa M; Szeto W; Papkoff J
Identification of a Wnt-responsive signal transduction pathway in primary endothelial cells | 19 | 8
|
| 19 | 3 | 19 1999 BIOCHEMICAL JOURNAL 344():565-570
Baulida J; Batlle E; de Herreros AG
Adenomatous polyposis coil protein (APC)-independent regulation of beta-catenin/Tcf-4 mediated transcription in intestinal cells | 7 | 5
|
| 20 | 2 | 20 1999 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1450(3):331-340
Wang B; Kishihara K; Zhang DL; Sakamoto T; Nomoto K
Transcriptional regulation of a receptor protein tyrosine phosphatase gene hPTP-J by PKC-mediated signaling pathways in Jurkat and Molt-4 T lymphoma cells | 1 | 0
|
| 21 | 5 | 21 1999 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1424(2-3):M23-M37
Roose J; Clevers H
TCF transcription factors: molecular switches in carcinogenesis | 53 | 0
|
| 22 | 7 | 22 1999 BIOESSAYS 21(12):1021-1030
Morin PJ
beta-catenin signaling and cancer | 181 | 73
|
| 23 | 1 | 23 1999 BRITISH JOURNAL OF CANCER 81(7):1116-1121
Park KS; Kim NG; Kim JJ; Kim H; Ahn YH; Choi KY
Differential regulation of MAP kinase cascade in human colorectal tumorigenesis | 7 | 0
|
| 24 | 3 | 24 1999 BULLETIN DU CANCER 86(4):336-336
Jeanteur P
beta-catenin, APC, C-MYC and the others... | 0 | 0
|
| 25 | 4 | 25 1999 BULLETIN DU CANCER 86(9):725-726
Durand M; Moles JP
beta-catenin mutations in a common skin cancer: pilomatricoma | 2 | 0
|
| 26 | 11 | 26 1999 CANCER AND METASTASIS REVIEWS 18(2):215-230
Smalley MJ; Dale TC
Wnt signalling in mammalian development and cancer | 33 | 13
|
| 27 | 12 | 27 1999 CANCER AND METASTASIS REVIEWS 18(2):231-246
Waltzer L; Bienz M
The control of beta-catenin and TCF during embryonic development and cancer | 15 | 4
|
| 28 | 1 | 28 1999 CANCER PREVENTION: NOVEL NUTRIENT AND PHARMACEUTICAL DEVELOPMENTS 889():20-31
Augenlicht LH; Bordonaro M; Heerdt BG; Mariadason J; Velcich A
Cellular mechanisms of risk and transformation | 9 | 2
|
| 29 | 1 | 29 1999 CANCER PREVENTION: NOVEL NUTRIENT AND PHARMACEUTICAL DEVELOPMENTS 889():32-44
Bertagnolli MM
APC and intestinal carcinogenesis - Insights from animal models | 4 | 0
|
| 30 | 1 | 30 1999 CANCER RESEARCH 59(2):269-273
Koch A; Denkhaus D; Albrecht S; Leuschner I; von Schweinitz D; Pietsch T
Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene | 95 | 44
|
| 31 | 1 | 31 1999 CANCER RESEARCH 59(4):826-830
Horikawa I; Cable PL; Afshari C; Barrett JJ
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene | 107 | 2
|
| 32 | 1 | 32 1999 CANCER RESEARCH 59(8):1811-1815
Garcia-Rostan G; Tallini G; Herrero A; D'Aquila TG; Carcangiu ML; Rimm DL
Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma | 90 | 0
|
| 33 | 1 | 33 1999 CANCER RESEARCH 59(8):1830-1833
Ogawa K; Yamada Y; Kishibe K; Ishizaki K; Tokusashi Y
beta-Catenin mutations are frequent in hepatocellular carcinomas but absent in adenomas induced by diethylnitrosamine in B6C3F1 mice | 28 | 7
|
| 34 | 1 | 34 1999 CANCER RESEARCH 59(12):2759-2765
Bieche I; Laurendeau I; Tozlu S; Olivi M; Vidaud D; Lidereau R; Vidaud M
Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay | 88 | 7
|
| 35 | 2 | 35 1999 CANCER RESEARCH 59(16):3880-3882
Koesters R; Ridder R; Kopp-Schneider A; Betts D; Adams V; Niggli F; Briner J; Doeberitz MV
Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors | 43 | 17
|
| 36 | 1 | 36 1999 CANCER RESEARCH 59(17):4213-4215
Duval A; Gayet J; Zhou XP; Iacopetta B; Thomas G; Hamelin R
Frequent frameshift mutations of the TCF-4 gene in colorectal cancers with microsatellite instability | 79 | 23
|
| 37 | 1 | 37 1999 CANCER RESEARCH 59(21):5403-5407
Lal A; Lash AE; Altschul SF; Velculescu V; Zhang L; McLendon RE; Marra MA; Prange C; Morin PJ; Polyak K; Papadopoulos N; Vogelstein B; Kinzler KW; Strausberg RL; Riggins GJ
A public database for gene expression in human cancers | 144 | 12
|
| 38 | 1 | 38 1999 CARCINOGENESIS 20(4):635-640
McEntee MF; Chiu CH; Whelan J
Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice | 29 | 9
|
| 39 | 1 | 39 1999 CARCINOGENESIS 20(9):1709-1713
Erdman SH; Ignatenko NA; Powell MB; Blohm-Mangone KA; Holubec H; Guillen-Rodriguez JM; Gerner EW
APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse | 14 | 4
|
| 40 | 2 | 40 1999 CELL 98(6):779-790
Johnston LA; Prober DA; Edgar BA; Eisenman RN; Gallant P
Drosophila myc regulates cellular growth during development | 109 | 9
|
| 41 | 4 | 41 1999 CELL 99(3):335-345
He TC; Chan TA; Vogelstein B; Kinzler KW
PPAR delta is an APC-regulated target of nonsteroidal anti-inflammatory drugs | 351 | 104
|
| 42 | 1 | 42 1999 CELL 99(4):399-408
Kim L; Liu JC; Kimmel AR
The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification | 48 | 6
|
| 43 | 1 | 43 1999 CELL GROWTH & DIFFERENTIATION 10(6):369-376
Caca K; Kolligs FT; Ji XD; Hayes M; Qian JM; Yahanda A; Rimm DL; Costa J; Fearon ER
beta- and gamma-catenin mutations, but not E-cadherin inactivation, underlie T-cell factor lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer | 42 | 23
|
| 44 | 1 | 44 1999 CELL GROWTH & DIFFERENTIATION 10(6):423-434
Foster KW; Ren SR; Louro ID; Lobo-Ruppert SM; McKie-Bell P; Grizzle W; Hayes MR; Broker TR; Chow LT; Ruppert JM
Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: Transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF | 15 | 2
|
| 45 | 1 | 45 1999 CELL GROWTH & DIFFERENTIATION 10(10):713-720
Bordonaro M; Mariadason JM; Aslam F; Heerdt BG; Augenlicht LH
Butyrate-induced apoptotic cascade in colonic carcinoma cells: Modulation of the beta-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin a but not curcumin | 28 | 9
|
| 46 | 1 | 46 1999 CELL PROLIFERATION 32(2-3):79-84
Del Buono R; Pignatelli M
The role of the E-cadherin complex in gastrointestinal cell differentiation | 1 | 0
|
| 47 | 6 | 47 1999 CELLULAR AND MOLECULAR LIFE SCIENCES 56(5-6):523-537
Novak A; Dedhar S
Signaling through beta-catenin and Lef/Tcf | 41 | 7
|
| 48 | 7 | 48 1999 CELLULAR SIGNALLING 11(11):777-788
Kikuchi A
Roles of axin in the Wnt signalling pathway | 39 | 13
|
| 49 | 2 | 49 1999 CHIRURGISCHE GASTROENTEROLOGIE 15(2):163-172
Gebert J; Doeberitz CV
Hereditary tumors of the gastrointestinal tract (FAP/HNPCC) | 3 | 0
|
| 50 | 1 | 50 1999 CLINICAL CANCER RESEARCH 5(5):945-951
Meyskens FL; Gerner EW
Development of difluoromethylornithine (DFMO) as a chemoprevention agent | 71 | 4
|
| 51 | 3 | 51 1999 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 64():141-147
Korswagen HC; Clevers HC
Activation and repression of Wingless/Wnt target genes by the TCF/LEF-1 family of transcription factors | 8 | 0
|
| 52 | 1 | 52 1999 COLON CANCER PREVENTION 470():15-22
Augenlicht L; Velcich A; Mariadason J; Bordonaro M; Heerdt B
Colonic cell proliferation, differentiation, and apoptosis | 4 | 0
|
| 53 | 1 | 53 1999 COLON CANCER PREVENTION 470():23-32
Polakis P; Hart M; Rubinfeld B
Defects in the regulation of beta-catenin in colorectal cancer | 22 | 8
|
| 54 | 1 | 54 1999 CURRENT BIOLOGY 9(2):R62-R65
Fearon ER; Dang CV
Cancer genetics: Tumor suppressor meets oncogene | 11 | 0
|
| 55 | 1 | 55 1999 CURRENT BIOLOGY 9(2):105-108
van Es JH; Kirkpatrick C; van de Wetering M; Molenaar M; Miles A; Kuipers J; Destree O; Peifer M; Clevers H
Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor | 37 | 0
|
| 56 | 2 | 56 1999 CURRENT OPINION IN CELL BIOLOGY 11(2):233-240
Eastman Q; Grosschedl R
Regulation of LEF-1/TCF transcription factors by Wnt and other signals | 144 | 31
|
| 57 | 1 | 57 1999 CURRENT OPINION IN GASTROENTEROLOGY 15(1):3-8
Shattuck-Brandt RL; DuBois RN
The molecular basis of colorectal carcinogenesis | 0 | 0
|
| 58 | 1 | 58 1999 CURRENT OPINION IN GENETICS & DEVELOPMENT 9(1):15-21
Polakis P
The oncogenic activation of beta-catenin | 207 | 100
|
| 59 | 3 | 59 1999 CURRENT OPINION IN MOLECULAR THERAPEUTICS 1(6):720-726
Lal A; Siu IM; Riggins GJ
Serial analysis of gene expression: Probing transcriptomes for molecular targets | 4 | 2
|
| 60 | 7 | 60 1999 CYTOKINE & GROWTH FACTOR REVIEWS 10(3-4):255-265
Kikuchi A
Modulation of Wnt signaling by Axin and Axil | 17 | 6
|
| 61 | 2 | 61 1999 DEVELOPMENT 126(10):2285-2298
Zhu AJ; Watt FM
beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion | 56 | 20
|
| 62 | 5 | 62 1999 DEVELOPMENT 126(20):4557-4568
DasGupta R; Fuchs E
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation | 77 | 13
|
| 63 | 1 | 63 1999 DEVELOPMENTAL BIOLOGY 207(2):350-363
Paulson AF; Fang X; Ji H; Reynolds AB; McCrea PD
Misexpression of the catenin p120(ctn)1A perturbs Xenopus gastrulation but does not elicit Wnt-directed axis specification | 11 | 0
|
| 64 | 1 | 64 1999 DIGESTION 60(6):544-548
Gerdes B; Ramaswamy A; Simon B; Pietsch T; Bastian D; Kersting M; Moll R; Bartsch D
Analysis of beta-catenin gene mutations in pancreatic tumors | 23 | 10
|
| 65 | 3 | 65 1999 EMBO JOURNAL 18(11):3054-3063
Damalas A; Ben-Ze'ev A; Simcha I; Shtutman N; Leal JFN; Zhurinsky J; Geiger B; Oren M
Excess beta-catenin promotes accumulation of transcriptionally active p53 | 65 | 24
|
| 66 | 1 | 66 1999 ENDOCRINE 10(1):67-76
Heinrich CA; Lail-Trecker MR; Peluso JJ; White BA
Negative regulation of N-cadherin-mediated cell-cell adhesion by the estrogen receptor signaling pathway in rat pituitary GH(3) cells | 7 | 1
|
| 67 | 1 | 67 1999 ENDOCRINE REVIEWS 20(2):207-239
Potter E; Bergwitz C; Brabant G
The cadherin-catenin system: Implications for growth and differentiation of endocrine tissues | 42 | 7
|
| 68 | 1 | 68 1999 EUROPEAN JOURNAL OF CANCER 35(3):335-351
Ilyas M; Straub J; Tomlinson IPM; Bodmer WF
Genetic pathways in colorectal and other cancers | 52 | 8
|
| 69 | 2 | 69 1999 EUROPEAN JOURNAL OF CANCER 35(14):1986-2002
Ilyas M; Straub J; Tomlinson IPM; Bodmer WF
Genetic pathways in colorectal and other cancers (Reprinted from Eur J Cancer, vol 35, pg 335-351, 1999) | 22 | 2
|
| 70 | 1 | 70 1999 EUROPEAN JOURNAL OF CANCER PREVENTION 8():S39-S47
Laurent-Puig P; Blons H; Cugnenc PH
Sequence of molecular genetic events in colorectal tumorigenesis | 16 | 0
|
| 71 | 5 | 71 1999 EXPERIMENTAL CELL RESEARCH 253(1):63-77
Dang CV; Resar LMS; Emison E; Kim S; Li Q; Prescott JE; Wonsey D; Zeller K
Function of the c-Myc oncogenic transcription factor | 66 | 2
|
| 72 | 1 | 72 1999 EXPERIMENTAL CELL RESEARCH 253(2):336-348
Uusitalo M; Heikkila M; Vainio S
Molecular genetic studies of Wnt signaling in the mouse | 23 | 0
|
| 73 | 1 | 73 1999 GENE 238(2):301-313
Krupnik VE; Sharp JD; Jiang C; Robison K; Chickering TW; Amaravadi L; Brown DE; Guyot D; Mays G; Leiby K; Chang B; Duong T; Goodearl ADJ; Gearing DP; Sokol SY; McCarthy SA
Functional and structural diversity of the human Dickkopf gene family | 35 | 1
|
| 74 | 1 | 74 1999 GENES & DEVELOPMENT 13(5):505-510
Maniatis T
A ubiquitin ligase complex essential for the NF-kappa B, Wnt/Wingless, and Hedgehog signaling pathways | 180 | 15
|
| 75 | 2 | 75 1999 GENES TO CELLS 4(8):465-474
Hamada F; Murata Y; Nishida A; Fujita F; Tomoyasu Y; Nakamura M; Toyoshima K; Tabata T; Ueno N; Akiyama T
Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC | 14 | 5
|
| 76 | 1 | 76 1999 GENOME RESEARCH 9(10):950-959
Ewing RM; Ben Kahla A; Poirot O; Lopez F; Audic S; Claverie JM
Large-scale statistical analyses of rice ESTs reveal correlated patterns of gene expression | 47 | 0
|
| 77 | 1 | 77 1999 GENOMICS 57(2):235-248
Wang YK; Sporle R; Paperna T; Schughart K; Francke U
Characterization and expression pattern of the frizzled gene Fzd9, the mouse homolog of FZD9 which is deleted in Williams-Beuren syndrome | 20 | 2
|
| 78 | 1 | 78 1999 GUT 45(5):730-732
Dimberg J; Samuelsson A; Hugander A; Soderkvist P
Differential expression of cyclooxygenase 2 in human colorectal cancer | 36 | 2
|
| 79 | 1 | 79 1999 HEPATOLOGY 29(4):1208-1214
Zimonjic DB; Keck CL; Thorgeirsson SS; Popescu NC
Novel recurrent genetic imbalances in human hepatocellular carcinoma cell lines identified by comparative genomic hybridization | 47 | 1
|
| 80 | 1 | 80 1999 HUMAN MOLECULAR GENETICS 8(8):1479-1485
Smith DP; Spicer J; Smith A; Swift S; Ashworth A
The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase | 23 | 0
|
| 81 | 1 | 81 1999 HUMAN MOLECULAR GENETICS 8(10):1821-1832
Claverie JM
Computational methods for the identification of differential and coordinated gene expression | 98 | 1
|
| 82 | 2 | 82 1999 IMMUNITY 11(4):433-442
Held W; Kunz B; Lowin-Kropf B; van de Wetering M; Clevers H
Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1 | 31 | 2
|
| 83 | 3 | 83 1999 IMMUNOLOGY AND CELL BIOLOGY 77(5):460-467
Leenen PJM; Egeler RM
Langerhans' cell histiocytosis is caused by dysregulation of the E-cadherin-beta-catenin cascade: A hypothesis | 3 | 0
|
| 84 | 1 | 84 1999 INTERNATIONAL JOURNAL OF CANCER 82(5):625-629
Wright K; Wilson P; Morland S; Campbell I; Walsh M; Hurst T; Ward B; Cummings M; Chenevix-Trench G
beta-catenin mutation and expression analysis in ovarian cancer: Exon 3 mutations and nuclear translocation in 16% of endometrioid tumours | 29 | 15
|
| 85 | 2 | 85 1999 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 4(5):541-544
Kucerova D; Sloncova E; Tuhackova Z; Uhlirova M; Kos M; Sovova V
Changes of E-cadherin and beta-catenin levels during induced differentiation of colorectal carcinoma cells | 6 | 0
|
| 86 | 1 | 86 1999 JAPANESE JOURNAL OF CANCER RESEARCH 90(8):824-828
Yamada Y; Yoshimi N; Sugie S; Suzui M; Matsunaga K; Kawabata K; Hara A; Mori H
beta-catenin (Ctnnb1) gene mutations in diethylnitrosamine (DEN)-induced liver tumors in male F344 rats | 8 | 1
|
| 87 | 3 | 87 1999 JAPANESE JOURNAL OF CANCER RESEARCH 90(12):1301-1309
Kondo Y; Kanai Y; Sakamoto M; Genda T; Mizokami M; Ueda R; Hirohashi S
beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma | 25 | 12
|
| 88 | 1 | 88 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(16):10681-10684
Yamamoto H; Kishida S; Kishida M; Ikeda S; Takada S; Kikuchi A
Phosphorylation of Axin, a Wnt signal negative regulator, by glycogen synthase kinase-3 beta regulates its stability | 87 | 40
|
| 89 | 1 | 89 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(23):16641-16645
Easwaran V; Song V; Polakis P; Byers S
The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of beta-catenin-lymphocyte enhancer-binding factor signaling | 32 | 13
|
| 90 | 2 | 90 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(25):18017-18025
Hecht A; Litterst CM; Huber O; Kemler R
Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro | 70 | 35
|
| 91 | 1 | 91 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(32):22705-22712
Spychala J; Zimmermann AG; Mitchell BS
Tissue-specific regulation of the ecto-5 '-nucleotidase promoter - Role of the cAMP response element site in mediating repression by the upstream regulatory region | 11 | 0
|
| 92 | 4 | 92 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(39):27682-27688
Kodama S; Ikeda S; Asahara T; Kishida M; Kikuchi A
Axin directly interacts with plakoglobin and regulates its stability | 28 | 20
|
| 93 | 1 | 93 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(42):29583-29586
Fry CJ; Farnham PJ
Context-dependent transcriptional regulation | 66 | 1
|
| 94 | 1 | 94 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(43):31062-31067
Alberta JA; Auger KR; Batt D; Iannarelli P; Hwang G; Elliott HL; Duke R; Roberts TM; Stiles CD
Platelet-derived growth factor stimulation of monocyte chemoattractant protein-1 gene expression is mediated by transient activation of the phosphoinositide 3-kinase signal transduction pathway | 10 | 0
|
| 95 | 2 | 95 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(49):35247-35254
Zhang Y; Neo SY; Wang XH; Han JH; Lin SC
Axin forms a complex with MEKK1 and activates c-Jun NH2-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling | 28 | 8
|
| 96 | 2 | 96 1999 JOURNAL OF CELL BIOLOGY 146(4):855-867
Orford K; Orford CC; Byers SW
Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest | 76 | 45
|
| 97 | 5 | 97 1999 JOURNAL OF CELL BIOLOGY 147(2):367-374
Nelson RW; Gumbiner BM
A cell-free assay system for beta-catenin signaling that recapitulates direct inductive events in the early Xenopus laevis embryo | 13 | 3
|
| 98 | 1 | 98 1999 JOURNAL OF CHILD NEUROLOGY 14(7):411-417
Adesina AM
Molecular heterogeneity in medulloblastoma with implications for differing tumor biology | 3 | 1
|
| 99 | 1 | 99 1999 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 84(4):1491-1492
Stratakis CA
Carney complex and related syndromes and their genetic loci - Response | 0 | 0
|
| 100 | 1 | 100 1999 JOURNAL OF CLINICAL PATHOLOGY 52(8):555-568
Michalides RJAM
Cell cycle regulators: mechanisms and their role in aetiology, prognosis, and treatment of cancer | 42 | 0
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 101 | 1 | 101 1999 JOURNAL OF INVESTIGATIVE DERMATOLOGY 113(2):258-262
Takata M; Fujimoto A; Aoki H; Hatta N; Ooi A; Takehara K
erbB-2 overexpression but no activation of beta-catenin gene in extramammary Paget's disease | 7 | 0
|
| 102 | 1 | 102 1999 JOURNAL OF THE NATIONAL CANCER INSTITUTE 91(11):916-932
Potter JD
Colorectal cancer: Molecules and populations | 193 | 6
|
| 103 | 1 | 103 1999 LABORATORY INVESTIGATION 79(12):1489-1499
Perry I; Tselepis C; Hoyland J; Iqbal TH; Sanders DSA; Cooper BT; Jankowski JAZ
Reduced cadherin/catenin complex expression in celiac disease can be reproduced in vitro by cytokine stimulation | 17 | 2
|
| 104 | 2 | 104 1999 M S-MEDECINE SCIENCES 15(3):427-428
L'Allemain G
The WISP genes, a family of novel connective tissue growth factors, are dysregulated in Wnt-1-transformed cells and in human colon cancer. | 0 | 0
|
| 105 | 1 | 105 1999 M S-MEDECINE SCIENCES 15(10):1105-1117
Perrin L; Arquier N; Semeriva M
Links between growth rate and proliferation revisited in Drosophila | 1 | 0
|
| 106 | 1 | 106 1999 MECHANISMS OF DEVELOPMENT 81(1-2):65-74
Vleminckx K; Kemler R; Hecht A
The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis | 22 | 8
|
| 107 | 1 | 107 1999 MELANOMA RESEARCH 9(5):421-432
Castellano M; Parmiani G
Genes involved in melanoma: overview of INK4a and other loci | 30 | 1
|
| 108 | 1 | 108 1999 MOLECULAR AND CELLULAR BIOLOGY 19(1):1-11
Dang CV
c-myc target genes involved in cell growth, apoptosis, and metabolism | 309 | 31
|
| 109 | 1 | 109 1999 MOLECULAR AND CELLULAR BIOLOGY 19(8):5576-5587
Gradl D; Kuhl M; Wedlich D
The Wnt/Wg signal transducer beta-catenin controls fibronectin expression | 83 | 49
|
| 110 | 5 | 110 1999 MOLECULAR AND CELLULAR BIOLOGY 19(8):5696-5706
Kolligs FT; Hu G; Dang CV; Fearon ER
Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression | 62 | 38
|
| 111 | 1 | 111 1999 MOLECULAR MEDICINE TODAY 5(4):172-177
Guilford P
E-cadherin downregulation in cancer: fuel on the fire? | 33 | 2
|
| 112 | 1 | 112 1999 NATURE 398(6726):422-426
Tetsu O; McCormick F
beta-catenin regulates expression of cyclin D1 in colon carcinoma cells | 698 | 498
|
| 113 | 2 | 113 1999 NATURE CELL BIOLOGY 1(3):144-151
Yu X; Waltzer L; Bienz M
A new Drosophila APC homologue associated with adhesive zones of epithelial cells | 46 | 13
|
| 114 | 2 | 114 1999 NATURE GENETICS 21(4):410-413
Chan EF; Gat U; McNiff JM; Fuchs E
A common human skin tumour is caused by activating mutations in beta-catenin | 155 | 69
|
| 115 | 1 | 115 1999 NATURE GENETICS 23(4):387-388
Velculescu VE; Madden SL; Zhang L; Lash AE; Yu J; Rago C; Lal A; Wang CJ; Beaudry GA; Ciriello KM; Cook BP; Dufault MR; Ferguson AT; Gao YH; He TC; Hermeking H; Hiraldo SK; Hwang PM; Lopez MA; Luderer HF; Mathews B; Petroziello JM; Polyak K; Zawel L; Zhang W; Zhang XM; Zhou W; Haluska FG; Jen J; Sukumar S; Landes GM; Riggins GJ; Vogelstein B; Kinzler KW
Analysis of human transcriptomes | 159 | 11
|
| 116 | 1 | 116 1999 ONCOGENE 18(4):849-854
Latres E; Chiaur DS; Pagano M
The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin | 81 | 22
|
| 117 | 1 | 117 1999 ONCOGENE 18(10):1903-1910
Ugolini F; Adelaide J; Charafe-Jauffret E; Nguyen C; Jacquemier J; Jordan B; Birnbaum D; Pebusque MJ
Differential expression assay of chromosome arm 8p genes identifies Frizzled-related (FRP1/FRZB) and Fibroblast Growth Factor Receptor 1 (FGFR1) as candidate breast cancer genes | 33 | 7
|
| 118 | 1 | 118 1999 ONCOGENE 18(15):2507-2517
Rosenwald IB; Chen JJ; Wang ST; Savas L; London IM; Pullman J
Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis | 36 | 2
|
| 119 | 1 | 119 1999 ONCOGENE 18(18):2883-2891
Crawford HC; Fingleton BM; Rudolph-Owen LA; Goss KJH; Rubinfeld B; Polakis P; Matrisian LM
The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors | 206 | 146
|
| 120 | 2 | 120 1999 ONCOGENE 18(19):2967-2987
Prendergast GC
Mechanisms of apoptosis by c-Myc | 152 | 8
|
| 121 | 2 | 121 1999 ONCOGENE 18(19):3004-3016
Nesbit CE; Tersak JM; Prochownik EV
MYC oncogenes and human neoplastic disease | 140 | 9
|
| 122 | 1 | 122 1999 ONCOGENE 18(33):4726-4733
Devereux TR; Anna CH; Foley JF; White CM; Sills RC; Barrett JC
Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis | 36 | 10
|
| 123 | 1 | 123 1999 ONCOGENE 18(34):4777-4787
Yamashita A; Hakura A; Inoue H
Suppression of anchorage-independent growth of human cancer cell lines by the drs gene | 8 | 1
|
| 124 | 1 | 124 1999 ONCOGENE 18(35):5010-5014
da Costa LT; He TC; Yu J; Sparks AB; Morin PJ; Polyak K; Laken S; Vogelstein B; Kinzler KW
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling | 31 | 0
|
| 125 | 3 | 125 1999 ONCOGENE 18(38):5325-5333
Heyer J; Yang K; Lipkin M; Edelmann W; Kucherlapati R
Mouse models for colorectal cancer | 25 | 6
|
| 126 | 2 | 126 1999 ONCOGENE 18(44):5959-5966
Gazit A; Yaniv A; Bafico A; Pramila T; Igarashi M; Kitajewski J; Aaronson SA
Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response | 8 | 4
|
| 127 | 2 | 127 1999 ONCOGENE 18(47):6583-6588
Terris B; Pineau P; Bregeaud L; Valla D; Belghiti J; Tiollais P; Degott C; Dejean A
Close correlation between beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas | 32 | 13
|
| 128 | 2 | 128 1999 ONCOGENE 18(48):6806-6809
Duval A; Iacopetta B; Ranzani GN; Lothe RA; Thomas G; Hamelin R
Variable mutation frequencies in coding repeats of TCF-4 and other target genes in colon, gastric and endometrial carcinoma showing microsatellite instability | 23 | 8
|
| 129 | 3 | 129 1999 ONCOGENE 18(50):7080-7090
Ito K; Okamoto I; Araki N; Kawano Y; Nakao M; Fujiyama S; Tomita K; Mimori T; Saya H
Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts | 19 | 0
|
| 130 | 11 | 130 1999 ONCOGENE 18(55):7860-7872
Miller JR; Hocking AM; Brown JD; Moon RT
Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways | 189 | 35
|
| 131 | 1 | 131 1999 ONCOLOGY REPORTS 6(6):1253-1256
Jaiswal AS; Kennedy CH; Narayan S
A correlation of APC and c-myc mRNA levels in lung cancer cell lines | 3 | 3
|
| 132 | 1 | 132 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(1):139-144
Aoki M; Hecht A; Kruse U; Kemler R; Vogt PK
Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1 | 59 | 27
|
| 133 | 1 | 133 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(4):1603-1608
Mann B; Gelos M; Siedow A; Hanski ML; Gratchev A; Ilyas M; Bodmer WF; Moyer MP; Riecken EO; Buhr HJ; Hanski C
Target genes of beta-catenin-T cell-factor lymphoid-enhancer-factor signaling in human colorectal carcinomas | 204 | 147
|
| 134 | 1 | 134 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(5):2322-2326
Laken SJ; Papadopoulos N; Petersen GM; Gruber SB; Hamilton SR; Giardiello FM; Brensinger JD; Vogelstein B; Kinzler KW
Analysis of masked mutations in familial adenomatous polyposis | 37 | 6
|
| 135 | 1 | 135 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(10):5522-5527
Shtutman M; Zhurinsky J; Simcha I; Albanese C; D'Amico M; Pestell R; Ben-Ze'ev A
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway | 351 | 229
|
| 136 | 1 | 136 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(20):11566-11571
Jayachandra S; Low KG; Thlick AE; Yu J; Ling PD; Chang Y; Moore PS
Three unrelated viral transforming proteins (vIRF, EBNA2, and E1A) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors (Retracted article. See vol 98, pg 12313, 2001) | 55 | 2
|
| 137 | 5 | 137 1999 PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY 72(3):299-328
Craig KL; Tyers M
The F-box: a new motif for ubiquitin dependent proteolysis in cell cycle regulation and signal transduction | 43 | 0
|
| 138 | 1 | 138 1999 SCIENCE 283(5410):2089-2091
Seeling JM; Miller JR; Gil R; Moon RT; White R; Virshup DM
Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A | 117 | 44
|
| 139 | 3 | 139 1999 SCIENCE 285(5435):1923-1926
Roose J; Huls G; van Beest M; Moerer P; van der Horn K; Goldschmeding R; Logtenberg T; Cleavers H
Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1 | 124 | 82
|
| 140 | 1 | 140 1999 SCIENCE 286(5444):1491-1492
Velculescu VE
Essay: Amersham Pharmacia Biotech & Science Prize - Tantalizing transcriptomes - SAGE and its use in global gene expression analysis | 18 | 1
|
| 141 | 2 | 141 1999 SCIENTIST 13(14):15-15
Kinzler KW
Hot papers - Cancer - Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC by P.J. Morin, A.B. Sparks, V. Korinek, N. Barker, H. Clevers, B. Vogelstein, K.W. Kinzler - Comments | 0 | 0
|
| 142 | 1 | 142 1999 SCIENTIST 13(8):15-15
Birchmeier W
Hot papers - Cell biology - Functional interaction of beta-catenin with the transcription factor LEF-I by J. Behrens, J.P. von Kries, M. Kuhl, L. Bruhn, D. Wedlich, R. Grosschedl, W. Birchmeier - Comments | 0 | 0
|
| 143 | 1 | 143 1999 SCIENTIST 13(2):24-24
[Anon]
Serial analysis of gene expression: An alternative to chip arrays | 0 | 0
|
| 144 | 1 | 144 1999 SEMINARS IN LIVER DISEASE 19(3):253-262
Chen PJ; Chen DS
Hepatitis B virus infection and hepatocellular carcinoma: Molecular genetics and clinical perspectives | 27 | 0
|
| 145 | 6 | 145 1999 TRENDS IN BIOCHEMICAL SCIENCES 24(12):M53-M56
McCormick F
Signalling networks that cause cancer | 6 | 0
|
| 146 | 6 | 146 1999 TRENDS IN CELL BIOLOGY 9(12):M53-M56
McCormick F
Signalling networks that cause cancer (Reprinted from Trends in Biochemical Science, vol 12, Dec., 1999) | 26 | 0
|
| 147 | 6 | 147 1999 TRENDS IN GENETICS 15(12):M53-M56
McCormick F
Signalling networks that cause cancer (Reprinted from Trends in Biochemical Sciences, vol 12, Dec., 1999) | 1 | 0
|
| 148 | 1 | 148 1999 TRENDS IN GENETICS 15(3):109-112
Greider CW
Telomerase activation - one step on the road to cancer? | 39 | 0
|
| 149 | 1 | 149 1999 UROLOGY 53(4):707-713
De Marzo AM; Knudsen B; Chan-Tack K; Epstein JI
E-cadherin expression as a marker of tumor aggressiveness in routinely processed radical prostatectomy specimens | 27 | 0
|
| 150 | 1 | 150 1999 WORLD JOURNAL OF GASTROENTEROLOGY 5(5):451-454
Zhang J; Lai MD; Chen J
Methylation status of p16 gene in colorectal carcinoma and normal colonic mucosa | 7 | 0
|
| 151 | 1 | 151 2000 ADVANCES IN CANCER RESEARCH, VOL 77 77():1-24
Barker N; Morin PJ; Clevers H
The yin-yang of TCF/beta-catenin signaling | 93 | 44
|
| 152 | 1 | 152 2000 ALIMENTARY PHARMACOLOGY & THERAPEUTICS 14(10):1231-1247
Smith AM; Watson SA
Review article: gastrin and colorectal cancer | 16 | 0
|
| 153 | 1 | 153 2000 AMERICAN JOURNAL OF CLINICAL PATHOLOGY 113(2):266-274
Kawanishi K; Doki Y; Shiozaki H; Yano M; Inoue M; Fukuchi N; Utsunomiya T; Watanabe H; Monden M
Correlation between loss of E-cadherin expression and overexpression of autocrine motility factor receptor in association with progression of human gastric cancers | 3 | 0
|
| 154 | 7 | 154 2000 AMERICAN JOURNAL OF PATHOLOGY 156(3):865-870
Brabletz T; Herrmann K; Jung A; Faller G; Kirchner T
Expression of nuclear beta-catenin and c-myc is correlated with tumor size but not with proliferative activity of colorectal adenomas | 43 | 24
|
| 155 | 2 | 155 2000 AMERICAN JOURNAL OF PATHOLOGY 156(6):1997-2005
Furuuchi K; Tada M; Yamada H; Kataoka A; Furuuchi N; Hamada J; Takahashi M; Todo S; Moriuchi T
Somatic mutations of the APC gene in primary breast cancers | 19 | 8
|
| 156 | 7 | 156 2000 AMERICAN JOURNAL OF PATHOLOGY 157(4):1113-1121
Kirchner T; Brabletz T
Patterning and nuclear beta-catenin expression in the colonic adenoma-carcinoma sequence - Analogies with embryonic gastrulation | 22 | 11
|
| 157 | 2 | 157 2000 AMERICAN JOURNAL OF PATHOLOGY 157(5):1563-1573
Wielenga VJM; van der Voort R; Taher TEI; Smit L; Beuling EA; van Krimpen C; Spaargaren M; Pals ST
Expression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancer | 12 | 1
|
| 158 | 2 | 158 2000 ANTICANCER RESEARCH 20(1A):407-416
Page C; Lin HJ; Jin Y; Castle VP; Nunez G; Huang M; Lin JY
Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis | 37 | 0
|
| 159 | 3 | 159 2000 ANTICANCER RESEARCH 20(5A):2835-2847
Papadopoulos V; Kapsis A; Li H; Amri H; Hardwick M; Culty M; Kasprzyk PG; Carlson M; Moreau JP; Drieu K
Drug-induced inhibition of the peripheral-type benzodiazepine receptor expression and cell proliferation in human breast cancer cells | 10 | 0
|
| 160 | 3 | 160 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 268(1):20-24
Tsuji T; Miyazaki M; Sakaguchi M; Inoue Y; Namba M
A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines | 9 | 0
|
| 161 | 7 | 161 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 268(2):243-248
Kikuchi A
Regulation of beta-catenin signaling in the Wnt pathway | 42 | 15
|
| 162 | 4 | 162 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 269(1):103-109
Koike J; Sagara N; Kirikoshi H; Takagi A; Miwa T; Hirai M; Katoh M
Molecular cloning and genomic structure of the beta TRCP2 gene on chromosome 5q35.1 | 49 | 8
|
| 163 | 5 | 163 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 272(1):144-150
Neo SY; Zhang Y; Yaw LP; Li P; Lin SC
Axin-induced apoptosis depends on the extent of its JNK activation and its ability to down-regulate beta-catenin levels | 16 | 7
|
| 164 | 4 | 164 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 276(3):1162-1169
Julius MA; Schelbert B; Hsu W; Fitzpatrick E; Jho E; Fagotto F; Costantini F; Kitajewski J
Domains of Axin and disheveled required for interaction and function in Wnt signaling | 7 | 3
|
| 165 | 3 | 165 2000 BIOCHEMISTRY-MOSCOW 65(1):2-27
Kopnin BP
Targets of oncogenes and tumor suppressors: Key for understanding basic mechanisms of carcinogenesis | 10 | 0
|
| 166 | 16 | 166 2000 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1495(2):168-182
Seidensticker MJ; Behrens J
Biochemical interactions in the wnt pathway | 67 | 11
|
| 167 | 4 | 167 2000 BIOESSAYS 22(10):902-910
Kitajewski J; Sassoon D
The emergence of molecular gynecology: homeobox and Wnt genes in the female reproductive tract | 9 | 0
|
| 168 | 16 | 168 2000 BIOESSAYS 22(11):961-965
Barker N; Clevers H
Catenins, Wnt signaling and cancer | 45 | 20
|
| 169 | 5 | 169 2000 BIOLOGICAL SIGNALS AND RECEPTORS 9(2):115-121
Peluso JJ
N-cadherin-mediated cell contact regulates ovarian surface epithelial cell survival | 13 | 1
|
| 170 | 3 | 170 2000 BLOOD 96(6):2206-2214
Hashimoto S; Suzuki T; Nagai S; Yamashita T; Toyoda N; Matsushima K
Identification of genes specifically expressed in human activated and mature dendritic cells through serial analysis of gene expression | 57 | 2
|
| 171 | 4 | 171 2000 BRITISH JOURNAL OF CANCER 83(1):1-5
Compagni A; Christofori G
Recent advances in research on multistage tumorigenesis | 27 | 1
|
| 172 | 12 | 172 2000 BRITISH JOURNAL OF SURGERY 87(8):992-1005
Wijnhoven BPL; Dinjens WNM; Pignatelli M
E-cadherin-catenin cell-cell adhesion complex and human cancer | 48 | 5
|
| 173 | 1 | 173 2000 CANCER GENETICS AND CYTOGENETICS 121(1):17-21
Masramon L; Ribas M; Cifuentes P; Arribas R; Garcia F; Egozcue J; Peinado MA; Miro R
Cytogenetic characterization of two colon cell lines by using conventional G-banding, comparative genomic hybridization, and whole chromosome painting | 12 | 0
|
| 174 | 3 | 174 2000 CANCER LETTERS 157(2):185-191
Akiyama Y; Nagasaki H; Yagi KO; Nomizu T; Yuasa Y
beta-Catenin and adenomatous polyposis coli (APC) mutations in adenomas from hereditary non-polyposis colorectal cancer patients | 3 | 0
|
| 175 | 3 | 175 2000 CANCER LETTERS 159(1):73-78
Murata M; Iwao K; Miyoshi Y; Nagasawa Y; Yabu M; Himeno S; Imanishi K; Ohsawa M; Wada H; Tominaga S; Shimano T; Kobayashi T; Nakamura Y
Activation of the beta-catenin gene by interstitial deletions involving exon 3 as an early event in colorectal tumorigenesis | 6 | 4
|
| 176 | 1 | 176 2000 CANCER RESEARCH 60(4):1070-1076
Hassan AB; Howell JA
Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice | 17 | 2
|
| 177 | 4 | 177 2000 CANCER RESEARCH 60(6):1671-1676
Shih IM; Tu J; He TC; Vogelstein B; Kinzler KW
The beta-catenin binding domain of adenomatous polyposis coil is sufficient for tumor suppression | 42 | 23
|
| 178 | 4 | 178 2000 CANCER RESEARCH 60(11):2864-2868
Anna CH; Sills RC; Foley JF; Stockton PS; Ton TV; Devereux TR
beta-Catenin mutations and protein accumulation in all hepatoblastomas examined from B6C3F1 mice treated with anthraquinone or oxazepam | 14 | 2
|
| 179 | 4 | 179 2000 CANCER RESEARCH 60(13):3323-3327
Yamada Y; Yoshimi N; Hirose Y; Kawabata K; Matsunaga K; Shimizu M; Hara A; Mori H
Frequent beta-catenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis | 35 | 8
|
| 180 | 7 | 180 2000 CANCER RESEARCH 60(13):3338-3342
Thompson WJ; Piazza GA; Li H; Liu L; Fetter J; Zhu B; Sperl G; Ahnen D; Pamukcu R
Exisulind induction of apoptosis involves guanosine 3 ',5 '-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin | 49 | 3
|
| 181 | 6 | 181 2000 CANCER RESEARCH 60(13):3354-3358
Kawasoe T; Furukawa Y; Daigo Y; Nishiwaki T; Ishiguro H; Fujita M; Satoh S; Miwa N; Nagasawa Y; Miyoshi Y; Ogawa M; Nakamura Y
Isolation and characterization of a novel human gene, DRCTNNB1A, the expression of which is down-regulated by beta-catenin | 6 | 6
|
| 182 | 5 | 182 2000 CANCER RESEARCH 60(14):3872-3879
Duval A; Rolland S; Tubacher E; Bui H; Thomas G; Hamelin R
The human T-cell transcription factor-4 gene: Structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines | 32 | 15
|
| 183 | 4 | 183 2000 CANCER RESEARCH 60(16):4602-4609
Bissonnette M; Khare S; von Lintig FC; Wali RK; Nguyen L; Zhang YC; Hart J; Skarosi S; Varki N; Boss GR; Brasitus TA
Mutational and nonmutational activation of p21(ras) in rat colonic azoxymethane-induced tumors: Effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1 | 19 | 1
|
| 184 | 2 | 184 2000 CANCER RESEARCH 60(21):6178-6183
Lewis BC; Prescott JE; Campbell SE; Shim H; Orlowski RZ; Dang CV
Tumor induction by the c-Myc target genes rcl and lactate dehydrogenase A | 3 | 0
|
| 185 | 5 | 185 2000 CANCER RESEARCH 60(22):6288-6292
Maiti S; Alam R; Amos CI; Huff V
Frequent association of beta-catenin and WT1 mutations in Wilms tumors | 14 | 7
|
| 186 | 3 | 186 2000 CANCER RESEARCH 60(22):6318-6325
Mitchell KO; Ricci MS; Miyashita T; Dicker DT; Jin ZY; Reed JC; El-Deiry WS
Bax is a transcriptional target and mediator of c-Myc-induced apoptosis | 26 | 1
|
| 187 | 8 | 187 2000 CANCER RESEARCH 60(22):6488-6495
Foster KW; Frost AR; McKie-Bell P; Lin CY; Engler JA; Grizzle WE; Ruppert JM
Increase of GKLF messenger RNA and protein expression during progression of breast cancer | 17 | 0
|
| 188 | 2 | 188 2000 CANCER RESEARCH 60(23):6611-6616
Tsujiuchi T; Tsutsumi M; Sasaki Y; Murata N; Konishi Y
Mutations of adenomatous polyposis coli and beta-catenin genes during progression of lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats | 14 | 5
|
| 189 | 10 | 189 2000 CANCER RESEARCH 60(23):6683-6687
Fujita M; Furukawa Y; Nagasawa Y; Ogawa M; Nakamura Y
Down-regulation of monocyte chemotactic protein-3 by activated beta-catenin | 4 | 4
|
| 190 | 5 | 190 2000 CANCER RESEARCH 60(24):7057-7065
Sasaki CY; Lin HC; Morin PJ; Longo DL
Truncation of the extracellular region abrogrates cell contact but retains the growth-suppressive activity of E-cadherin | 9 | 0
|
| 191 | 2 | 191 2000 CARCINOGENESIS 21(3):469-476
Bach SP; Renehan AG; Potten CS
Stem cells: the intestinal stem cell as a paradigm | 47 | 2
|
| 192 | 2 | 192 2000 CARCINOGENESIS 21(6):1167-1173
Mutanen M; Pajari AM; Oikarinen SI
Beef induces and rye bran prevents the formation of intestinal polyps in Apc(Min) mice: relation to beta-catenin and PKC isozymes | 26 | 2
|
| 193 | 2 | 193 2000 CARCINOGENESIS 21(11):1935-1940
Iwamoto M; Ahnen DJ; Franklin WA; Maltzman TH
Expression of beta-catenin and full-length APC protein in normal and neoplastic colonic tissues | 15 | 9
|
| 194 | 1 | 194 2000 CARDIOVASCULAR RESEARCH 45(3):621-629
Rezvani M; Barrans JD; Dai KS; Liew CC
Apoptosis-related genes expressed in cardiovascular development and disease: an EST approach | 7 | 0
|
| 195 | 4 | 195 2000 CELL 100(1):143-155
Fuchs E; Segre JA
Stem cells: A new lease on life | 182 | 5
|
| 196 | 15 | 196 2000 CELL 103(2):311-320
Bienz M; Clevers H
Linking colorectal cancer to Wnt signaling | 190 | 60
|
| 197 | 4 | 197 2000 CELL ADHESION AND COMMUNICATION 7(5):391-408
Luber B; Candidus S; Handschuh G; Mentele E; Hutzler P; Feller S; Voss J; Hofler H; Becker KF
Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate | 8 | 2
|
| 198 | 1 | 198 2000 CELL GROWTH & DIFFERENTIATION 11(4):201-210
Ngo CV; Gee M; Akhtar N; Yu D; Volpert O; Auerbach R; Thomas-Tikhonenko A
An in vivo function for the transforming Myc protein: Elicitation of the angiogenic phenotype | 21 | 1
|
| 199 | 2 | 199 2000 CELL PROLIFERATION 33(1):1-18
Roncucci L; Pedroni M; Vaccina F; Benatti P; Marzona L; De Pol A
Aberrant crypt foci in colorectal carcinogenesis. Cell and crypt dynamics | 22 | 1
|
| 200 | 1 | 200 2000 CELLULAR & MOLECULAR BIOLOGY LETTERS 5(1):3-18
Miturski R; Burnouf D; Nothisen M; Bogusiewicz M; Jakowicki JA
Molecular biology and clinical implications of the adenomatous polyposis coli (APC) gene | 1 | 0
|
| # | Cited
nodes | Nodes / Authors | GCS | LCS |
| 201 | 4 | 201 2000 CELLULAR AND MOLECULAR LIFE SCIENCES 57(8-9):1207-1219
Desterro JMP; Rodriguez MS; Hay RT
Regulation of transcription factors by protein degradation | 16 | 0
|
| 202 | 1 | 202 2000 CHINESE SCIENCE BULLETIN 45(21):1973-1977
Lin GT; Zhang ZW; Zang T; Xin DQ; Chang ZJ; Guo YL
Interaction of hTCF4 by yeast two-hybrid system | 1 | 0
|
| 203 | 2 | 203 2000 CHIRURGISCHE GASTROENTEROLOGIE 16(3):206-212
Muller H; Dobbie Z; Heinimann K
Familial colorectal cancer and genetic screening | 1 | 0
|
| 204 | 2 | 204 2000 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 65():511-520
Wahl G; Vafa O
Genetic instability, oncogenes, and the p53 pathway | 0 | 0
|
| 205 | 3 | 205 2000 COLORECTAL CANCER: NEW ASPECTS OF MOLECULAR BIOLOGY AND IMMUNOLOGY AND THEIR CLINICAL APPLICATIONS 910():1-9
Hanski C; Itzkowitz SH
Translating the knowledge of molecular alterations that occur during colon carcinogenesis into clinically relevant solutions | 2 | 0
|
| 206 | 13 | 206 2000 COLORECTAL CANCER: NEW ASPECTS OF MOLECULAR BIOLOGY AND IMMUNOLOGY AND THEIR CLINICAL APPLICATIONS 910():21-35
Behrens J
Control of beta-catenin signaling in tumor development | 45 | 12
|
| 207 | 4 | 207 2000 CRITICAL REVIEWS IN ONCOGENESIS 11(1):19-62
Feo F; Pascale RM; Simile MM; De Miglio MR; Muroni MR; Calvisi D
Genetic alterations in liver carcinogenesis: Implications for new preventive and therapeutic strategies | 15 | 2
|
| 208 | 5 | 208 2000 CURRENT OPINION IN GASTROENTEROLOGY 16(5):419-425
Su GH; Kern SE
Molecular genetics of ductal pancreatic neoplasia | 2 | 0
|
| 209 | 4 | 209 2000 CURRENT OPINION IN GENETICS & DEVELOPMENT 10(1):81-93
Macleod K
Tumor suppressor genes | 35 | 2
|
| 210 | 4 | 210 2000 CURRENT OPINION IN MOLECULAR THERAPEUTICS 2(6):682-690
Ricci MS; El-Deiry WS
Novel strategies for therapeutic design in molecular oncology using gene expression profiles | 5 | 0
|
| 211 | 3 | 211 2000 CYTOGENETICS AND CELL GENETICS 88(3-4):264-265
Duval A; Busson-Leconiat M; Berger R; Hamelin R
Assignment of the TCF-4 gene (TCF7L2) to human chromosome band 10q25.3 | 3 | 2
|
| 212 | 12 | 212 2000 CYTOKINE & GROWTH FACTOR REVIEWS 11(4):273-282
Akiyama T
Wnt/beta-catenin signaling | 24 | 6
|
| 213 | 4 | 213 2000 DEVELOPMENT 127(3):469-482
Galceran J; Miyashita-Lin EM; Devaney E; Rubenstein JLR; Grosschedl R
Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1 | 44 | 3
|
| 214 | 10 | 214 2000 DEVELOPMENT 127(17):3805-3813
Lickert H; Domon C; Huls G; Wehrle C; Duluc I; Clevers H; Meyer BI; Freund JN; Kemler R
Wnt/beta-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine | 43 | 6
|
| 215 | 6 | 215 2000 DEVELOPMENTAL BIOLOGY 219(1):98-114
Widelitz RB; Jiang TX; Lu JF; Chuong CM
beta-catenin in epithelial morphogenesis: Conversion of part of avian foot scales into feather buds with a mutated beta-catenin | 33 | 2
|
| 216 | 3 | 216 2000 DRUG DISCOVERY TODAY 5(9):415-425
Madden SL; Wang CJ; Landes G
Serial analysis of gene expression: from gene discovery to target identification | 21 | 2
|
| 217 | 8 | 217 2000 EMBO JOURNAL 19(10):2270-2279
Spink KE; Polakis P; Weis WI
Structural basis of the Axin-adenomatous polyposis coli interaction | 27 | 5
|
| 218 | 5 | 218 2000 EMBO JOURNAL 19(21):5813-5823
Beier R; Burgin A; Kiermaier A; Fero M; Karsunky H; Saffrich R; Moroy T; Ansorge W; Roberts J; Eilers M
Induction of cyclin E-cdk2 kinase activity, E2F-dependent transcription and cell growth by Myc are genetically separable events | 32 | 2
|
| 219 | 4 | 219 2000 EMBO REPORTS 1(6):519-523
Neufeld KL; Zhang F; Cullen BR; White RL
APC-mediated downregulation of beta-catenin activity involves nuclear sequestration and nuclear export | 29 | 10
|
| 220 | 4 | 220 2000 ENDOCRINE 12(3):295-302
Peluso JJ; Pappalardo A; Hess SA
Effect of disrupting cell contact on the nuclear accumulation of beta-catenin and subsequent apoptosis of rat ovarian surface epithelial cells in vitro | 5 | 2
|
| 221 | 2 | 221 2000 ENDOCRINE PATHOLOGY 11(3):243-250
Semba S; Kusumi R; Moriya T; Sasano H
Nuclear accumulation of beta-catenin in human endocrine tumors: Association with Ki-67 (MIB-1) proliferative activity | 4 | 1
|
| 222 | 2 | 222 2000 EPITHELIAL TRANSPORT AND BARRIER FUNCTION 915():136-143
Gessner R; Tauber R
Intestinal cell adhesion molecules - Liver-intestine cadherin | 5 | 0
|
| 223 | 2 | 223 2000 EUROPEAN JOURNAL OF CANCER 36(2):242-248
Jonsson M; Borg A; Nilbert M; Andersson T
Involvement of adenomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer | 19 | 6
|
| 224 | 3 | 224 2000 EUROPEAN JOURNAL OF CANCER 36(5):664-674
Smith ML; Hawcroft G; Hull MA
The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action | 60 | 4
|
| 225 | 1 | 225 2000 EUROPEAN JOURNAL OF CANCER 36(8):1043-1049
Bourgarel-Rey V; El Khyari S; Rimet O; Bordas B; Guigal N; Braguer D; Seree E; Barra Y; Briand C
Opposite effects of antimicrotubule agents on c-myc oncogene expression depending on the cell lines used | 3 | 0
|
| 226 | 3 | 226 2000 EUROPEAN JOURNAL OF CANCER 36(13):1607-1620
Beavon IRG
The E-cadherin-catenin complex in tumour metastasis: structure, function and regulation | 33 | 6
|
| 227 | 23 | 227 2000 EXPERIMENTAL CELL RESEARCH 261(1):75-82
Ben-Ze'ev A; Shtutman M; Zhurinsky J
The integration of cell adhesion with gene expression: The role of beta-catenin | 24 | 0
|
| 228 | 4 | 228 2000 FEBS LETTERS 476(3):203-207
Dang DT; Bachman KE; Mahatan CS; Dang LH; Giardiello FM; Yang VW
Decreased expression of the gut-enriched Kruppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients | 17 | 1
|
| 229 | 3 | 229 2000 FRONTIERS IN BIOSCIENCE 5():D372-D390
Amanatullah DF; Reutens AT; Zafonte BT; Fu MF; Mani S; Pestell RG
Cell-cycle dysregulation and the molecular mechanisms of prostate cancer | 13 | 0
|
| 230 | 8 | 230 2000 GASTROENTEROLOGY 119(3):854-865
Chung DC
The genetic basis of colorectal cancer: Insights into critical pathways of tumorigenesis | 78 | 10
|
| 231 | 3 | 231 2000 GENES & DEVELOPMENT 14(2):158-162
Dorsky RI; Raible DW; Moon RT
Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway | 34 | 3
|
| 232 | 1 | 232 2000 GENES & DEVELOPMENT 14(3):272-277
Kung AL; Rebel VI; Bronson RT; Ch'ng LE; Sieff CA; Livingston DM; Yao TP
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP | 97 | 2
|
| 233 | 5 | 233 2000 GENES & DEVELOPMENT 14(5):585-595
Xu LF; Corcoran RB; Welsh JW; Pennica D; Levine AJ
WISP-1 is a Wnt-1-and beta-catenin-responsive oncogene | 67 | 38
|
| 234 | 1 | 234 2000 GENES & DEVELOPMENT 14(8):889-894
Robinson GW; Hennighausen L; Johnson PF
Side-branching in the mammary gland: the progesterone-Wnt connection | 17 | 2
|
| 235 | 15 | 235 2000 GENES & DEVELOPMENT 14(11):1319-1331
Kolligs FT; Kolligs B; Hajra KM; Hu G; Tani M; Cho KR; Fearon ER
gamma-Catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin | 74 | 41
|
| 236 | 5 | 236 2000 GENES & DEVELOPMENT 14(13):1553-1577
Goodman RH; Smolik S
CBP/p300 in cell growth, transformation, and development | 286 | 4
|
| 237 | 24 | 237 2000 GENES & DEVELOPMENT 14(15):1837-1851
Polakis P
Wnt signaling and cancer | 448 | 140
|
| 238 | 4 | 238 2000 GENES CHROMOSOMES & CANCER 28(4):443-453
Webster MT; Rozycka M; Sara E; Davis E; Smalley M; Young N; Dale TC; Wooster R
Sequence variants of the axin gene in breast, colon, and other cancers: An analysis of mutations that interfere with GSK3 binding | 43 | 20
|
| 239 | 3 | 239 2000 GENOME RESEARCH 10(12):2006-2021
Chrast R; Scott HS; Papasavvas MP; Rossier C; Antonarakis ES; Barras C; Davisson MT; Schmidt C; Estivill X; Dierssen M; Pritchard M; Antonarakis SE
The mouse brain transcriptome by SAGE: Differences in gene expression between P30 brains of the partial trisomy 16 mouse model of Down syndrome (Ts65Dn) and normals | 18 | 0
|
| 240 | 2 | 240 2000 GLIA 32(2):146-154
Gunnersen JM; Spirkoska V; Smith PE; Danks RA; Tan SS
Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression | 21 | 4
|
| 241 | 1 | 241 2000 GUT 47(6):812-819
Kishimoto Y; Takata N; Jinnai T; Morisawa T; Shiota G; Kawasaki H; Hasegawa J
Sulindac and a cyclooxygenase-2 inhibitor, etodolac, increase APC mRNA in the colon of rats treated with azoxymethane | 9 | 5
|
| 242 | 1 | 242 2000 GUT 47(6):820-824
Smith AM; Watson SA
Gastrin and gastrin receptor activation: an early event in the adenoma-carcinoma sequence | 26 | 1
|
| 243 | 6 | 243 2000 GYNECOLOGIC ONCOLOGY 77(1):97-104
Furlong MT; Morin PJ
Rare activation of the TCF/beta-catenin pathway in ovarian cancer | 10 | 3
|
| 244 | 2 | 244 2000 HARVEY LECTURES, SERIES 94, 1998-1999 94():47-+
Fuchs E
Beauty is skin deep: The fascinating biology of the epidermis and its appendages | 0 | 0
|
| 245 | 1 | 245 2000 HISTOLOGY AND HISTOPATHOLOGY 15(1):251-260
Tucker EL; Pignatelli M
Catenins and their associated proteins in colorectal cancer | 11 | 2
|
| 246 | 3 | 246 2000 HUMAN GENE THERAPY 11(16):2261-2266
Watt FM
Epidermal stem cells as targets for gene transfer | 6 | 0
|
| 247 | 5 | 247 2000 IMMUNITY 13(1):15-24
Reya T; O'Riordan M; Okamura R; Devaney E; Willert K; Nusse R; Grosschedl R
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism | 49 | 11
|
| 248 | 3 | 248 2000 IMMUNOLOGICAL REVIEWS 175():94-103
O'Riordan M; Grosschedl R
Transcriptional regulation of early B-lymphocyte differentiat |