Nodes: 4464, Authors: 8653, Journals: 638, Outer References: 124402, Words: 7994
Collection span: 1971 - 2005
View: Overview. Sorted by GCS.
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#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
3601	2	12	2229 1997 JOURNAL OF CHEMICAL RESEARCH-S (12):470-471 Easton CJ; Kelly JB; Ward CM Regioselective hydrogen-atom transfer from triglycine	1	2
3602	2	15	2230 1997 JOURNAL OF COORDINATION CHEMISTRY 41(3):223-232 Tian YN; Yang P; Li QS; Liu SX Synthesis, molecular structure and tumor-inhibiting properties of nickel(II) and cobalt(II) complexes of 2,2'-diamino-4,4'-bithiazole. Crystal structure of [NiL2(SO4)(MeOH)]center dot 3MeOH	0	2
3603	7	24	2322 1997 NUCLEOSIDES & NUCLEOTIDES 16(7-9):1261-1270 Plunkett W; Huang P; Gandhi V Gemcitabine: Actions and interactions	0	2
3604	24	41	2347 1997 TETRAHEDRON 53(35):12005-12016 Ashley GW; Lawrence CC; Stubbe J; Robins MJ Mechanism based inactivation of the adenosylcobalamin-dependent ribonucleotide reductase from L-leichmannii by 2'-ara-2'-azido-2'-deoxy adenosine-5'-triphosphate: Observation of paramagnetic intermediates	2	2
3605	17	31	2350 1997 TETRAHEDRON LETTERS 38(33):5877-5880 Jung PMJ; Dauvergne J; Burger A; Biellmann JF Cyclization by free radical addition of stannyl or thiyl radical to 3'- beta-ethynyl uridine. Is the 3'-beta-ethynyl group a spin trap in ribonucleotide reductase?	0	2
3606	2	17	2366 1998 ACTA BOTANICA SINICA 40(7):615-621 Yong WD; Liang TB; Xie AY; Cong L; Song YR phbB, phbC gene expression in E-coli and their transformation and identification in potato	0	2
3607	1	1	2459 1998 CHEMICAL REVIEWS 98(7):2661-2661 STUBBE J; van der Donk WA Protein radicals in enzyme catalysis (vol 98, pg 705, 1998)	2	2
3608	20	88	2554 1998 JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN 56(11):987-999 Takahashi T; Tanaka H; Doi T; Yamada H Recent progress in syntheses of 9-membered masked enediyne analogues and their DNA cleaving activities	0	2
3609	1	55	2608 1998 LEUKEMIA & LYMPHOMA 31(1-2):21-37 Matthews JH The cytotoxic effect of the vitamin B-12 inhibitor cyanocobalamin [c-lactam], and a review of other vitamin B-12 antagonists	0	2
3610	1	88	2609 1998 MEDICAL HYPOTHESES 51(3):223-233 Fischer KM Expanded (CAG)(n), (CGG)(n) and (GAA)(n) trinucleotide repeat microsatellites, and mutant purine synthesis and pigmentation genes cause schizophrenia and autism	0	2
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
3611	10	1252	2657 1999 ADVANCES IN HETEROCYCLIC CHEMISTRY, VOL 73 73:295-395 Belen'Kii LI; Kruchkovskaya ND; Gramenitskaya VN The literature of heterocyclic chemistry, part VI	0	2
3612	4	43	2671 1999 ANTICANCER RESEARCH 19(2A):1109-1115 Schreiber G; Pitterle D; Kim YC; Bepler G Molecular genetic analysis of primary lung cancer and cancer metastatic to the lung	0	2
3613	5	46	2675 1999 APPLIED MAGNETIC RESONANCE 16(2):223-236 Schwartz DA; Walter ED; M; cIlwain SJ; Krymov VN; et al. High-frequency (94.9 GHz) EPR spectroscopy of paramagnetic centers in a neutron-irradiated sapphire single-crystal fiber	0	2
3614	6	35	2691 1999 BIOCHEMISTRY 38(12):3615-3623 Yang XM; Tellier P; Masson JY; Vu T; Ramotar D Characterization of amino acid substitutions that severely alter the DNA repair functions of Escherichia coli endonuclease IV	0	2
3615	3	47	2716 1999 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1428(2-3):433-445 Saksena R; Deepak D; Khare A; Sahai R; Tripathi LM; et al. A novel pentasaccharide from immunostimulant oligosaccharide fraction of buffalo milk	0	2
3616	9	47	2726 1999 BIOPOLYMERS 52(3):110-128 Rajani C; Kincaid JR; Petering DH A systematic approach toward the analysis of drug-DNA interactions using Raman spectroscopy: The binding of metal-free bleomycins A(2) and B-2 to calf thymus DNA	2	2
3617	22	81	2747 1999 COORDINATION CHEMISTRY REVIEWS 186:837-858 Kessissoglou DP Homo-and mixed-valence EPR -active trinuclear manganese complexes	1	2
3618	4	61	2763 1999 HELVETICA CHIMICA ACTA 82(6):848-869 Kontaxis G; Riether D; Hannak R; Tollinger M; Krautler B Electrochemical synthesis and structure analysis of neocoenzyme B-12 - An epimer of coenzyme B-12 with a remarkably flexible organometallic group	0	2
3619	11	33	2825 1999 JOURNAL OF CHEMICAL RESEARCH-S (2):98-99 Kumbhar AS; Damle SG; Dasgupta ST; Rane SY; Kumbhar AS Nuclease activity of oxo-bridged diiron complexes	0	2
3620	3	31	2844 1999 JOURNAL OF MOLECULAR EVOLUTION 48(4):482-492 Kanai S; Toh H Identification of new members of the GS ADP-forming family from the de novo purine biosynthesis pathway	1	2
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
3621	6	112	2849 1999 JOURNAL OF ORGANIC CHEMISTRY 64(12):4492-4501 Gao DQ; Pan YK Monte Carlo investigations of solvent effects on the decarboxylation reaction of neutral N-carboxy-2-imidazolidinone in aqueous solution	0	2
3622	4	22	2890 1999 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (22):3239-3241 Lim J; Kim YH Stereoselective synthesis of 1 'beta-2 ',3 '-dideoxy-2 '- bis(ethoxycarbonyl)methyluridine nucleosides by ring opening of cyclopropanated glycals	0	2
3623	5	21	2897 1999 MACROMOLECULES 32(10):3347-3352 Horowitz DM; Brennan EM; Koon JJ; Gerngross TU Novel thermal route to an amorphous, film-forming polymer latex	1	2
3624	4	82	2902 1999 METAL IONS IN BIOLOGICAL SYSTEMS, VOL 36 36:389-413 Hartmann HJ; Sievers C; Weser U Thiyl radicals in biochemically important thiols in the presence of metal ions	0	2
3625	2	36	2925 1999 PARASITOLOGY RESEARCH 85(3):188-193 Lye LF; Hsu JY; Singh AK; Su KE; Lee ST Characterization by pulse-field electrophoresis of a new region of DNA amplification containing the M-2 subunit of ribonucleotide reductase in hydroxyurea-resistant Leishmania	0	2
3626	5	16	2956 1999 TETRAHEDRON LETTERS 40(26):4807-4810 Etheve-Quelquejeu M; Valery JM Synthesis of 2 '-alpha-C-allenyl-2 '-deoxyuridine: An analogue of 2 '- azido-2 '-deoxyuridine, known inhibitor of ribonucleotide diphosphate reductase (RDPR).	0	2
3627	4	20	2959 1999 TETRAHEDRON-ASYMMETRY 10(10):1851-1854 Giordano A; Spinella A; Sodano G Stereoselective synthesis of 4-amino-3-hydroxy-2-methylpentanoic acids: stereochemistry of the amino acid occurring in the marine toxin janolusimide	0	2
3628	2	65	2973 2000 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 66(10):4279-4291 Rothermich MM; Guerrero R; Lenz RW; Goodwin S Characterization, seasonal occurrence, and diel fluctuation of poly(hydroxyalkanoate) in photosynthetic microbial mats	0	2
3629	1	41	2996 2000 BIOCHEMISTRY 39(29):8556-8564 Born TL; Franklin M; Blanchard JS Enzyme-catalyzed acylation of homoserine: Mechanistic characterization of the Haemophilus influenzae met2-encoded homoserine transacetylase	1	2
3630	14	51	2999 2000 BIOCHEMISTRY 39(31):9514-9522 Vialas C; Pratviel G; Meunier B Oxidative damage generated by an oxo-metalloporphyrin onto the human telomeric sequence	0	2
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
3631	18	33	3023 2000 BIOORGANIC & MEDICINAL CHEMISTRY 8(5):1065-1073 Highfield JA; Mehta LK; Parrick J; Wardman P Synthesis, hydroxyl radical production and cytotoxicity of analogues of bleomycin	0	2
3632	2	39	3026 2000 BIOORGANIC CHEMISTRY 28(2):98-118 McPhee MM; Kern JT; Hoster BC; Kerwin SM Propargylic sulfone-armed lariat crown ethers: Alkali metal ion-regulated DNA cleavage agents	0	2
3633	2	12	3041 2000 CHEMICAL COMMUNICATIONS (7):553-554 Lim J; Choo DJ; Kim YH Diastereoselective synthesis of alpha-substituted-gamma-butyrolactones of nucleosides via [1,5]-C,H insertion reactions of alpha-diazomalonates of nucleosides	0	2
3634	6	12	3044 2000 CHEMICAL PHYSICS LETTERS 325(1-3):69-72 O'Malley PJ Density functional studies of phenoxyl-Na+ ion complexes: implications for tyrosyl free radical interactions in vitro	0	2
3635	16	25	3047 2000 CHEMICAL PHYSICS LETTERS 331(1):108-114 Boulet AM; Walter ED; Schwartz DA; Gerfen GJ; Callis PR; et al. Electronic structure and hyperfine interactions in thioether-substituted tyrosyl radicals	2	2
3636	13	38	3056 2000 CHINESE JOURNAL OF INORGANIC CHEMISTRY 16(3):374-384 Liu CL; Yu SW; Xu HB; Zhou JY Progress on the mechanisms for double-stranded DNA scission mediated by transition metal complexes	0	2
3637	2	8	3057 2000 CHINESE SCIENCE BULLETIN 45(12):1079-1082 Li J; Yang SM; Zhang FX; Tang ZX; Shi QZ; et al. Synthesis, crystal structure and properties of binuclear manganese complex [(bipy)(2)Mn-2(mu-O)(mu-Ac)(2)(H2O)(2)](ClO4)(2)	0	2
3638	3	56	3058 2000 CHINESE SCIENCE BULLETIN 45(17):1546-1554 Yang CM Evidence for oxidative damage to prion protein in prion diseases	1	2
3639	8	62	3090 2000 INORGANIC CHEMISTRY 39(4):757-764 Collinson S; Alcock NW; Raghunathan A; Kahol PK; Busch DH Synthesis and properties of iron(II) and manganese(II) complexes derived from a topologically constrained pentadentate ligand	0	2
3640	9	33	3109 2000 INORGANICA CHIMICA ACTA 304(2):204-209 Brooker S; Dunbar GS; Plieger PG Complexation of copper(II) with acyclic amide ligands: structure of an unexpected rearrangement product resulting from an intramolecular reaction of an amine with an amide	0	2
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
3641	24	40	3141 2000 JOURNAL OF INORGANIC BIOCHEMISTRY 79(1-4):59-65 Twitchett MB; Dobbing AM; Sykes AG New mechanistic insights into the reactivity of the R2 protein of E-coli ribonucleotide reductase (RNR)	2	2
3642	7	27	3145 2000 JOURNAL OF MICROBIOLOGICAL METHODS 41(1):1-8 de Roo G; Ren Q; Witholt B; Kessler B Development of an improved in vitro activity assay for medium chain length PHA polymerases based on Coenzyme A release measurements	1	2
3643	5	27	3171 2000 JOURNAL OF RAMAN SPECTROSCOPY 31(12):1073-1077 Weselucha-Birczynska A; Strahan GD; Tsuboi M; Nakamoto K Interaction of bleomycin A(2) with DNA studied by resonance Raman spectroscopy: intercalation or groove binding?	2	2
3644	2	48	3212 2000 JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS (19):3445-3452 Chen ZX; Karasek N; Craig DC; Colbran SB Copper(II/I) complexes of a bulky tris(pyrazolylmethyl)amine ligand	0	2
3645	8	23	3251 2000 SYNTHESIS AND REACTIVITY IN INORGANIC AND METAL-ORGANIC CHEMISTRY 30(4):683-693 Liao ZR; Xiang DF; Li DF; Sheng F; Mei FS; et al. Synthesis, crystal structure and spectral properties of a triply bridged diiron(III) complex, [Fe-2(IDB)(2)(mu-O)(mu-OAc)(2)]Cl-2 center dot Ch(3)OH	0	2
3646	2	26	3252 2000 SYNTHETIC COMMUNICATIONS 30(13):2259-2268 Huang PQ; Tang X; Chen AQ An alternative stereoselective synthesis of protected trans-5-alkyl-4-hydroxy-2-pyrrolidinones	0	2
3647	1	16	3255 2000 TETRAHEDRON LETTERS 41(44):8595-8599 Dang HS; Roberts BP Strategy for contra-thermodynamic radical-chain epimerisation of 1,2-diols using polarity-reversal catalysis	1	2
3648	18	30	3256 2000 TETRAHEDRON LETTERS 41(49):9493-9498 Boger DL; Aquila BM; Tse WC; Searcey M Synthesis and evaluation of a novel bleomycin A(2) analogue: continuing assessment of the linker domain	1	2
3649	1	21	3327 2001 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 11(19):2565-2568 Conn C; Shimmon R; Cordaro F; Hargraves TL; Ibrahim P Combinatorial synthesis of SSAO inhibitors using Sonogashira coupling: SAR of aryl propargylic amines	0	2
3650	23	47	3344 2001 CHEMICAL RESEARCH IN TOXICOLOGY 14(5):528-535 Lopez-Larraza DM; Moore K; Dedon PC Thiols alter the partitioning of calicheamicin-induced deoxyribose 4 '- oxidation reactions in the absence of DNA radical repair	1	2
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
3651	7	30	3345 2001 CHEMICAL RESEARCH IN TOXICOLOGY 14(10):1413-1420 Angeloff A; Dubey I; Pratviel G; Bernadou J; Meunier B Characterization of a 5 '-aldehyde terminus resulting from the oxidative attack at C5 ' of a 2-deoxyribose on DNA	0	2
3652	12	23	3348 2001 CHIMIA 55(4):275-280 Giese B Radicals and the birth and death of DNA	1	2
3653	18	66	3369 2001 EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (11):2823-2829 Mukhopadhyay U; Falvello LR; Ray D Synthesis and crystal structure of a novel binucleating symmetrical mu-bis(tetradentate) Schiff base ligand: Syntheses and redox properties of dimanganese(III/III) complexes	0	2
3654	2	22	3381 2001 INFECTION AND IMMUNITY 69(4):2542-2548 Donovan M; Schumuke JJ; Fonzi WA; Bonar SL; Gheesling-Mullis K; et al. Virulence of a phosphoribosylaminoimidazole carboxylase-deficient Candida albicans strain in an immunosuppressed murine model of systemic candidiasis	0	2
3655	6	74	3415 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(26):24030-24037 Krupenko SA; Vlasov AP; Wagner C On the role of conserved histidine 106 in 10-formyltetrahydrofolate dehydrogenase catalysis - Connection between hydrolase and dehydrogenase mechanisms	0	2
3656	10	29	3456 2001 JOURNAL OF PHYSICAL CHEMISTRY A 105(30):7267-7272 Freindorf M; Kozlowski PM DFT study of the metal coordination center domain of Fe(II)-bleomycin	1	2
3657	8	65	3495 2001 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (3):305-315 Moutel S; Prandi J Synthesis of novel analogues of the calicheamicin gamma(I)(1) and esperamicin A(1B) oligosaccharides	0	2
3658	8	46	3500 2001 MACROMOLECULES 34(20):6889-6894 Kamachi M; Zhang SM; Goodwin S; Lenz RW Enzymatic polymerization and characterization of new poly(3-hydroxyalkanoate)s by a bacterial polymerase	1	2
3659	5	34	3520 2001 NUCLEIC ACIDS RESEARCH 29(24) Henn A; Halfon J; Kela I; Orion I; Sagi I Nucleic acid fragmentation on the millisecond timescale using a conventional X-ray rotating anode source: application to protein-DNA footprinting	0	2
3660	10	191	3544 2001 PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 70 70:233-289 Keller U; Schauwecker F Nonribosomal biosynthesis of microbial chromopeptides	0	2
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
3661	6	13	3549 2001 SCIENCE 294(5551):2489-2490 Frey PA Enzymology - Coenzymes and radicals	1	2
3662	2	26	3552 2001 SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 57(3):513-519 Hanai K; Kuwae A; Takai T; Senda H; Kunimoto KK A comparative vibrational and NMR study of cis-cinnamic acid polymorphs and trans-cinnamic acid	0	2
3663	11	27	3563 2002 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 58:2209-2212 Lehtio L; Leppanen VM; Kozarich JW; Goldman A Structure of Escherichia coli pyruvate formate-lyase with pyruvate	0	2
3664	3	39	3576 2002 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 68(1):93-101 Hai T; Oppermann-Sanio FB; Steinbuchel A Molecular characterization of a thermostable cyanophycin synthetase from the thermophilic cyanobacterium Synechococcus sp strain MA19 and in vitro synthesis of cyanophycin and related Polyamides	0	2
3665	3	27	3588 2002 BIOCHEMICAL PHARMACOLOGY 63(5):967-975 Buschini A; Alessandrini C; Martino A; Pasini L; Rizzoli V; et al. Bleomycin genotoxicity and amifostine (WR-2721) cell protection in normal leukocytes vs. K562 tumoral cells	0	2
3666	15	43	3593 2002 BIOCHEMISTRY 41(3):897-905 Kuo HM; Chao PDL; Chin DH Delocalized electronic structure of the thiol sulfur substantially prevents nucleic acid damage induced by neocarzinostatin	1	2
3667	15	39	3598 2002 BIOCHEMISTRY 41(12):3984-3990 Umback NJ; Norton JR Indirect determination of the rate of iron uptake into the apoprotein of the ribonucleotide reductase of E-coli	2	2
3668	10	55	3616 2002 BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 80(6):789-796 Wang HJ; Ramotar D Cellular resistance to bleomycin in Saccharomyces cerevisiae is not affected by changes in bleomycin hydrolase levels	1	2
3669	3	29	3623 2002 BIOORGANIC & MEDICINAL CHEMISTRY 10(5):1321-1328 Hakimelahi GH; Gassanov GS; Hsu MH; Hwu JR; Hakimelahi S A novel approach towards studying non-genotoxic enediynes as potential anticancer therapeutics	0	2
3670	2	18	3625 2002 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12(1):1-4 Warner PM; Qi JW; Meng B; Li G; Xie LF; et al. DNA cleavage by aromatic amines	0	2
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
3671	3	82	3629 2002 BIOPHYSICAL JOURNAL 83(5):2440-2456 Calvo R; Isaacson RA; Abresch EC; Okamura MY; Feher G Spin-lattice relaxation of coupled metal-radical spin-dimers in proteins: Application to Fe2+-cofactor (Q(A), Q(B), phi) dimers in reaction centers from photosynthetic bacteria	0	2
3672	2	17	3630 2002 BIOTECHNOLOGY LETTERS 24(4):245-250 Solaiman DKY Polymerase-chain-reaction-based detection of individual polyhydroxyalkanoate synthase phaC1 and phaC2 genes	1	2
3673	9	23	3632 2002 BIOTECHNOLOGY LETTERS 24(12):1011-1016 Solaiman DKY; Ashby RD; Foglia TA Synthesis of poly(hydroxyalkanoates) by Escherichia coli expressing mutated and chimeric PHA synthase genes	1	2
3674	8	80	3634 2002 BULLETIN DU CANCER 89(4):369-379 Azria D; Jacot W; Prost P; Culine S; Ychou M; et al. Gemcitabine and ionizing radiations: radiosensitization or radio-chemotherapy combination	0	2
3675	5	31	3638 2002 CANCER LETTERS 187(1-2):41-46 Kosinska W; Pelle E; von Pressentin MDM; Chen M; Guttenplan JB Comparative mutagenicities of bleomycin and ferric-nitrilotriacetate in lacZ mice	0	2
3676	3	56	3643 2002 CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 23(2):243-250 Yang CM Organic chemistry in Neurodegenerative disorders - Physical organic chemistry and bioorganic free radical chemistry of prion protein	0	2
3677	1	15	3650 2002 COLLOID JOURNAL 64(4):472-477 Pomogailo AD; Vlasenko VG; Shuvaev AT; Rozenberg AS; Dzhardimalieva GI The study of the mechanism of the local order formation near the iron atoms during thermolysis of [Fe3O(OOCCH=CHCOOH)(6)]OH center dot 3H(2)O as the initial stage of nanoparticle nucleation in metal-polymer systems	1	2
3678	1	49	3654 2002 CURRENT MEDICINAL CHEMISTRY 9(18):1677-1688 Su TL Development of DNA topoisomerase II-mediated anticancer agents, 3-(9-acridinylamino)-5-hydroxymethylanilines (AHMAs) and related compounds	0	2
3679	8	32	3666 2002 ENZYME KINETICS AND MECHANISM, PT F: DETECTION AND CHARACTERIZATION OF ENZYME REACTION INTERMEDIATES 354:426-435 Frey PA; Chang CH; Ballinger MD; Reed GH Kinetic characterization of transient free radical intermediates in reaction of lysine 2,3-aminomutase by EPR lineshape analysis	1	2
3680	7	23	3674 2002 EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (8):1941-1944 Moll NRPY; Banse F; Miki K; Nierlich M; Girerd JJ Hydroxylation of hexane using dioxygen and trimethylhydroquinone: Biomimetic catalysis by an unsymmetrical diiron-mu-oxo complex	1	2
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3681	1	36	3748 2002 JOURNAL OF MEDICAL MICROBIOLOGY 51(1):34-41 Maegavva T; Karasawa T; Ohta T; Wang XM; Kato H; et al. Linkage between toxin production and purine biosynthesis in Clostridium difficile	0	2
3682	7	62	3759 2002 JOURNAL OF ORGANIC CHEMISTRY 67(6):1898-1904 Chambert S; Thomasson F; Decout JL 2-trimethylsilylethyl sulfides in the von Braun cyanogen bromide reaction: Selective preparation of thiocyanates and application to nucleoside chemistry	0	2
3683	4	14	3760 2002 JOURNAL OF ORGANIC CHEMISTRY 67(19):6820-6822 Chang MCY; Miller SE; Carpenter SD; Stubbe J; Nocera DG Nanosecond generation of tyrosyl radicals via laser-initiated decaging of oxalate-modified amino acids	2	2
3684	1	20	3812 2002 MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 501(1-2):105-113 Parsian AJ; Funk MC; Tao TY; Hunt CR The effect of DNA damage on the formation of protein/DNA complexes	0	2
3685	15	19	3815 2002 NATURE STRUCTURAL BIOLOGY 9(4):236-238 Ludwig ML; Matthews RG Effector regulation in a monomeric enzyme	2	2
3686	26	50	3820 2002 NUCLEIC ACIDS RESEARCH 30(22):4881-4891 Wu W; Vanderwall DE; Turner CJ; Hoehn S; Chen JY; et al. Solution structure of the hydroperoxide of Co(III) phleomycin complexed with d(CCAGGCCTGG)(2): evidence for binding by partial intercalation	2	2
3687	19	63	3821 2002 NUCLEIC ACIDS RESEARCH 30(24):5497-5508 Junker HD; Hoehn ST; Bunt RC; Marathius V; Chen JY; et al. Synthesis, characterization and solution structure of tethered oligonucleotides containing an internal 3 '-phosphoglycolate, 5 '-phosphate gapped lesion	2	2
3688	0	43	3826 2002 PEDIATRIC RESEARCH 52(6):879-885 Williams SJ; McMillen IC; Zaragoza DB; Olson DM Placental restriction increases the expression of prostaglandin endoperoxide G/H synthase-2 and EP2 mRNA in the fetal sheep kidney during late gestation	1	2
3689	8	30	3831 2002 POLYMER DEGRADATION AND STABILITY 77(1):77-85 Sudesh K; Gan ZH; Maehara A; Doi Y Surface structure, morphology and stability of polyhydroxyalkanoate inclusions characterised by atomic force microscopy	2	2
3690	16	98	3848 2002 SEIKAGAKU 74(2):87-102 Toraya T Radical-catalyzed enzymatic reactions: Structure and mechanism of B-12 enzymes	2	2
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3691	8	17	3855 2002 TETRAHEDRON LETTERS 43(12):2243-2245 Fujimoto K; Ikeda Y; Ishihara S; Saito I Deoxyribonolactone formation in photoirradiation of 5-bromouracil-containing oligonucleotides by direct C1 ' hydrogen abstraction	0	2
3692	0	44	3874 2003 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 285(5):F881-F888 Zhang MZ; Wang SW; Cheng HF; Zhang YH; McKanna JA; et al. Regulation of renal cortical cyclooxygenase-2 in young rats	0	2
3693	3	31	3885 2003 ARCHIVES OF MICROBIOLOGY 179(6):437-443 Segura D; Cruz T; Espin G Encystment and alkylresorcinol production by Azotobacter vinelandii strains impaired in poly-beta-hydroxybutyrate synthesis	0	2
3694	8	24	3894 2003 BIOCHEMISTRY 42(15):4578-4584 Chen DW; Abend A; Stubbe J; Frey PA Epimerization at carbon-5 ' of (5 ' R)-[5 ',H-2]adenosylcobalamin by ribonucleoside triphosphate reductase: Cysteine 408-independent cleavage of the Co-C5 ' bond	3	2
3695	15	50	3898 2003 BIOCHEMISTRY 42(20):6201-6208 Smoukov SK; Davydov RM; Doan PE; Sturgeon B; Kung IY; et al. EPR and ENDOR evidence for a 1-His, hydroxo-bridged mixed-valent dilron site in Desulfovibrio vulgaris rubrerythrin	0	2
3696	33	77	3915 2003 BIOPOLYMERS 71(2):117-131 Cooperman BS Oligopeptide inhibition of class I ribonucleotide reductases	0	2
3697	5	66	3921 2003 BRITISH JOURNAL OF CANCER 88(12):1963-1970 Bergman AM; Pinedo HM; Talianidis I; Veerman G; Loves WJP; et al. Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines	0	2
3698	10	64	3924 2003 CANCER RESEARCH 63(20):6935-6941 Robinson BW; Im MM; Ljungman M; Praz F; Shewach DS Enhanced radiosensitization with gemcitabine in mismatch repair-deficient HCT116 cells	1	2
3699	3	14	3926 2003 CHEMICAL COMMUNICATIONS (15):1828-1829 Mukherjee S; Rentschler E; Weyhermuller T; Wieghardt K; Chaudhuri P Unique series of dinuclear transition metal-polyradical complexes with a m-phenylenediamine spacer and their catalytic reactivity	1	2
3700	7	50	3933 2003 CHEMICAL RESEARCH IN TOXICOLOGY 16(12):1539-1546 Zang H; Gates KS Sequence specificity of DNA alkylation by the antitumor natural product leinamycin	0	2
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3701	45	67	3947 2003 CHEMISTRY-A EUROPEAN JOURNAL 9(23):5916-5925 Fernandes PA; Ramos MJ Theoretical studies on the mode of inhibition of ribonucleotide reductase by 2 '-substituted substrate analogues	2	2
3702	11	53	3963 2003 DALTON TRANSACTIONS (15):3136-3144 Paine TK; Weyhermuller T; Bothe E; Wieghardt K; Chaudhuri P Manganese complexes of mixed O, X, O-donor ligands (X = S or Se): synthesis, characterization and catalytic reactivity	2	2
3703	3	42	3977 2003 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (16):3173-3178 Jargstorff C; Wille U Self-terminating radical oxygenations: Probing of the scope of the concept by use of various organic O-centered radicals	1	2
3704	3	41	3979 2003 FUNGAL GENETICS AND BIOLOGY 40(2):159-165 Alejandre-Duran E; Roldan-Arjona T; Ariza RR; Ruiz-Rubio M The photolyase gene from the plant pathogen Fusarium oxysporum f. sp lycopersici is induced by visible light and alpha-tomatine from tomato plant	0	2
3705	17	66	3986 2003 INORGANIC CHEMISTRY 42(17):5244-5251 Liu TQ; Lovell T; Han WG; Noodleman L DFT calculations of isomer shifts and quadrupole splitting parameters in synthetic iron-oxo complexes: Applications to methane monooxygenase and ribonucleotide reductase	1	2
3706	30	54	3988 2003 INORGANIC CHEMISTRY 42(23):7519-7530 Costas M; Cady CW; Kryatov SV; Ray M; Ryan MJ; et al. Role of carboxylate bridges in modulating nonheme diiron(II)/O-2 reactivity	1	2
3707	24	119	3989 2003 INORGANIC CHEMISTRY 42(26):8652-8662 Kuzelka J; Farrell JR; Lippard SJ Modeling the syn disposition of nitrogen donors at the active sites of carboxylate-bridged diiron enzymes. Enforcing dinuclearity and kinetic stability with a 1,2-diethynylbenzene-based ligand	0	2
3708	4	30	3991 2003 INORGANICA CHIMICA ACTA 348:115-122 Sheriff TS; Carr P; Piggott B Manganese catalysed reduction of dioxygen to hydrogen peroxide: structural studies on a manganese(III)-catecholate complex	1	2
3709	8	41	3992 2003 INTERNATIONAL JOURNAL OF ONCOLOGY 22(1):201-207 Van Moorsel CJA; Smid K; Voorn DA; Bergman AM; Pinedo HM; et al. Effect of gemcitabine and cis-platinum combinations on ribonucleotide and deoxyribonucleotide pools in ovarian cancer cell lines	0	2
3710	1	54	4008 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(45):44496-44504 Lindner HA; Lunin VV; Alary A; Hecker R; Cygler M; et al. Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family	0	2
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3711	3	48	4009 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(47):46826-46831 Liu XQ; Yang J; Meng Q Four inteins and three group II introns encoded in a bacterial ribonucleotide reductase gene	0	2
3712	37	78	4014 2003 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 8(5):549-559 Papakyriakou A; Mouzopoulou B; Katsaros N The solution structure of the Ga(III)-bleomycin A2 complex resolved by NMR and molecular modeling; interaction with d(CCAGGCCTGG)	3	2
3713	8	50	4017 2003 JOURNAL OF COMPUTATIONAL CHEMISTRY 24(7):797-805 Arnaud P; Zakrzewska K; Meunier B Theoretical study of the interaction between a high-valent manganese porphyrin oxyl-(hydroxo)-Mn(IV)-TMPyP and double-stranded DNA	0	2
3714	9	43	4024 2003 JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 13(2):182-190 Kim TK; Shin HD; Seo MC; Lee JN; Lee YH Molecular structure of PCR cloned PHA synthase genes of Pseudomonas putida KT2440 and its utilization for medium-chain length polyhydroxyalkanoate production	0	2
3715	23	63	4037 2003 JOURNAL OF PHYSICAL CHEMISTRY B 107(1):331-337 Kaupp M; Gress T; Reviakine R; Malkina OL; Malkin VG g tensor and spin density of the modified tyrosyl radical in galactose oxidase: A density functional study	1	2
3716	15	67	4039 2003 JOURNAL OF PHYSICAL CHEMISTRY B 107(17):4182-4188 Magistrato A; DeGrado WF; Laio A; Rothlisberger U; VandeVondele J; et al. Characterization of the dizinc analogue of the synthetic diiron protein DF1 using ab initio and hybrid quantum/classical molecular dynamics simulations	0	2
3717	11	26	4040 2003 JOURNAL OF PHYSICAL CHEMISTRY B 107(24):5751-5757 Lucas MD; Fernandes PA; Eriksson LA; Ramos MJ Pyruvate formate lyase: A new perspective	1	2
3718	6	29	4041 2003 JOURNAL OF PHYSICAL ORGANIC CHEMISTRY 16(7):373-379 Lal M; Langels A; Deiseroth HJ; Schlirf J; Schmittel M Role of hydrogen bonding in the oxidation potential of enols	1	2
3719	13	98	4045 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(2):570-579 Khoroshun DV; Warncke K; Ke SC; Musaev DG; Morokuma K Internal degrees of freedom, structural motifs, and conformational energetics of the 5-deoxyadenosyl radical: Implications for function in adenosylcobalamin-dependent enzymes. A computational study	1	2
3720	10	80	4049 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(8):2272-2281 Ramirez-Arizmendi LE; Heidbrink JL; Guler LP; Kenttamaa HI Reactivity of substituted charged phenyl radicals toward components of nucleic acids	0	2
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3721	6	62	4053 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(17):5005-5014 Lakshmi KV; Poluektov OG; Reifler MJ; Wagner AM; Thurnauer MC; et al. Pulsed high-frequency EPR study on the location of carotenoid and chlorophyll cation radicals in photosystem II	0	2
3722	4	95	4061 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(24):7461-7469 Gil A; Bertran J; Sodupe M Gas phase dissociation energies of saturated AH(n)(center dot)(+) radical cations and AH(n) neutrals (A = Li-F, Na-Cl): Dehydrogenation, deprotonation, and formation of AH(n)(center dot)(+)-H-2 complexes	0	2
3723	57	90	4069 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(34):10194-10205 Rishel MJ; Thomas CJ; Tao ZF; Vialas C; Leitheiser CJ; et al. Conformationally constrained analogues of bleomycin A(5)	1	2
3724	47	76	4071 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(36):10810-10821 Kemsley JN; Zaleski KL; Chow MS; Decker A; Shishova EY; et al. Spectroscopic studies of the interaction of ferrous bleomycin with DNA	2	2
3725	18	28	4075 2003 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125(37):11200-11201 Mitic N; Saleh L; Schenk G; Bollinger JM; Solomon EI Rapid-freeze-quench magnetic circular dichroism of intermediate X in ribonucleotide reductase: New structural insight	2	2
3726	0	41	4085 2003 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 14(10):2428-2435 De Jong JC; Willems PHGM; Van den Heuvel LPWJ; Knoers NVAM; Bindels RJM Functional expression of the human thiazide-sensitive NaCl cotransporter in Madin-Darby canine kidney cells	0	2
3727	10	100	4087 2003 JOURNAL OF THE INDIAN CHEMICAL SOCIETY 80(2):69-78 Reddy KH Nuclease activity of transition metal complexes - a review	1	2
3728	1	80	4095 2003 MOLECULAR CANCER RESEARCH 1(8):577-588 Oleinik NV; Krupenko SA Ectopic expression of 10-formyltetrahydrofolate dehydrogenase in A549 cells induces G(1) cell cycle arrest and apoptosis	0	2
3729	16	36	4208 2004 BIOCHEMISTRY 43(32):10314-10327 Hoskins AA; Anand R; Ealick SE; Stubbe J The formylglycinamide ribonucleotide amidotransferase complex from Bacillus subtilis: Metabolite-mediated complex formation	2	2
3730	15	54	4209 2004 BIOCHEMISTRY 43(32):10328-10342 Anand R; Hoskins AA; Stubbe J; Ealick SE Domain organization of Salmonella typhimurium formylglycinamide ribonucleotide amidotransferase revealed by X-ray crystallography	2	2
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3731	3	19	4210 2004 BIOCHEMISTRY 43(32):10343-10352 Anand R; Hoskins AA; Bennett EM; Sintchak MD; Stubbe J; et al. A model for the Bacillus subtilis formylglycinamide ribonucleotide amidotransferase multiprotein complex	2	2
3732	14	53	4240 2004 CANCER RESEARCH 64(3):1102-1109 Aouida M; Page N; Leduc A; Peter M; Ramotar D A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to the anticancer drug bleomycin	1	2
3733	54	426	4251 2004 CHEMICAL REVIEWS 104(2):459-508 Noodleman L; Lovell T; Han WG; Li J; Himo F Quantum chemical studies of intermediates and reaction pathways in selected enzymes and catalytic synthetic systems	0	2
3734	30	340	4269 2004 CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY 39(1):21-68 Hausinger RP Fe(II)/alpha-ketoglutarate-dependent hydroxylases and related enzymes	0	2
3735	13	31	4291 2004 FEMS MICROBIOLOGY LETTERS 230(2):265-274 Handrick R; Technow U; Reichart T; Reinhardt S; Sander T; et al. The activator of the Rhodospirillum rubrum PHB depolymerase is a polypeptide that is extremely resistant to high temperature (121 degrees C) and other physical or chemical stresses	2	2
3736	10	27	4294 2004 FREE RADICAL RESEARCH 38(1):59-66 Engalytcheff A; Kolberg M; Barra AL; Andersson KK; Tilquin B The use of multi-frequency EPR techniques to identify the radicals produced in irradiated beta-blockers	0	2
3737	1	40	4296 2004 GENES & DEVELOPMENT 18(10):1154-1164 Furuya K; Poitelea M; Guo L; Caspari T; Carr AM Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BCRT domains of Rad4(TOPBP1)	0	2
3738	9	63	4302 2004 INORGANIC CHEMISTRY 43(1):303-308 Holder AA; Swavey S; Brewer KJ Design aspects for the development of mixed-metal supramolecular complexes capable of visible light induced photocleavage of DNA	0	2
3739	13	86	4321 2004 INTERNATIONAL JOURNAL OF MASS SPECTROMETRY 234(1-3):101-122 Wee S; O'Hair RAJ; McFadyen WD Comparing the gas-phase fragmentation reactions of protonated and radical cations of the tripeptides GXR	2	2
3740	7	66	4328 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(2):1206-1216 Turnbull JJ; Nakajima J; Welford RWD; Yamazaki M; Saito K; et al. Mechanistic studies on three 2-oxoglutarate-dependent oxygenases of flavonoid biosynthesis - Anthocyanidin synthase, flavonol synthase, and flavanone 3 beta-hydroxylase	1	2
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3741	11	34	4330 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(9):7606-7612 Zhao XB; Girotto S; Yu SW; Magliozzo RS Evidence for radical formation at Tyr-353 in Mycobacterium tuberculosis catalase-peroxidase (KatG)	0	2
3742	26	43	4352 2004 JOURNAL OF COMPUTATIONAL CHEMISTRY 25(3):311-321 Pelmenschikov V; Cho KB; Siegbahn PEM Class I ribonucleotide reductase revisited: The effect of removing a proton on Glu441	2	2
3743	3	123	4364 2004 JOURNAL OF MOLECULAR BIOLOGY 336(3):787-807 Mao LS; Wang YL; Liu YM; Hu XC Molecular determinants for ATP-binding in proteins: A data mining and quantum chemical analysis	0	2
3744	13	64	4383 2004 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 126(2):591-598 Choi SH; Cooley RB; Hakemian AS; Larrabee YC; Bunt RC; et al. Mechanism of two-electron oxidation of deoxyguanosine 5 '-monophosphate by a platinum(IV) complex	0	2
3745	23	71	4385 2004 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 126(7):2237-2246 van Gastel M; Lubitz W; Lassmann G; Neese F Electronic structure of the cysteine thiyl radical: A DFT and correlated ab initio study	0	2
3746	1	94	4414 2004 MOLECULAR AND CELLULAR BIOLOGY 24(10):4151-4165 Baroni E; Viscardi V; Cartagena-Lirola H; Lucchini G; Longhese MP The functions of budding yeast Sae2 in the DNA damage response require Mec1-and Tel1-dependent phosphorylation	0	2
3747	9	53	4424 2004 NUCLEIC ACIDS RESEARCH 32(3):926-935 Koval VV; Kuznetsov NA; Zharkov DO; Ishchenko AA; Douglas KT; et al. Pre-steady-state kinetics shows differences in processing of various DNA lesions by Escherichia coli formamidopyrimidine-DNA glycosylase	0	2
3748	4	37	4432 2004 ORGANOMETALLICS 23(12):2838-2840 Llewellyn DB; Arndtsen BA Design, synthesis, and characterization of a new class of amino acid-based chiral borate counteranions	0	2
3749	2	19	4444 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(19):7252-7257 Leduc D; Graziani S; Lipowski G; Marchand C; Le Marechal P; et al. Functional evidence for active site location of tetrameric thymidylate synthase X at the interphase of three monomers	0	2
3750	1	21	144 1985 BIOCHEMICAL JOURNAL 227(1):311-316 MILLER DA; STEPHENSJARNAGIN A; DELUCA HF THE EPITHELIAL DIFFERENTIATING ACTIVITY INVIVO OF (E)-4-[2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHYLENYL)-1-PROPENYL]BENZOIC ACID AND 4,4-DIFLUORORETINOIC ACID	0	1
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3751	7	29	647 1990 JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN 48(3):194-205 OWA T; SUGIYAMA T; SUGA A; OTSUKA M; OHNO M SYNTHETIC STUDY TOWARD MAN-MADE BLEOMYCINS BY DEEPLY CONTRIBUTING TO THE ANTICANCER MECHANISM OF NATURAL BLEOMYCINS	0	1
3752	1	7	700 1990 TETRAHEDRON LETTERS 31(11):1557-1558 DESPAX C; NAVECH J NEW THIO-ANALOGS OF PHOSPHOENOL PYRUVATE	0	1
3753	1	62	714 1991 ANTIBIOTIKI I KHIMIOTERAPIYA 36(4):32-35 KIRSANOV AY; MIRONOV VA; DANILENKO VN ROLE OF PROPYONYL-KOA-CARBOXYLASE IN BIOSYNTHESIS OF ANTIBIOTICS	0	1
3754	1	94	765 1991 INORGANIC CHEMISTRY 30(2):228-239 XIN J; ZON G; MARZILLI LG MULTINUCLEAR NMR INVESTIGATION OF ZN-2+ BINDING TO A DODECAMER OLIGODEOXYRIBONUCLEOTIDE - INSIGHTS FROM C-13 NMR-SPECTROSCOPY	0	1
3755	1	20	790 1991 JOURNAL OF INORGANIC BIOCHEMISTRY 43(4):779-787 KOZLOWSKI H; RADOMSKA B; KISS T; BALLA J; NAKONIECZNA L; et al. COORDINATION OF COPPER(II) IONS TO CATECHOYL-DIPEPTIDES, THE INHIBITORS OF LEUCINE AMINOPEPTIDASE AND RIBONUCLEOTIDE REDUCTASE	0	1
3756	3	21	923 1992 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 56(3):394-398 UEDA K; HIASA H; TAKEBE S; SAKAI H; KOMANO T ALTERNATIVE SECONDARY STRUCTURES IN THE PHAGE-G4 ORIGIN OF THE COMPLEMENTARY-DNA STRAND SYNTHESIS - EFFECTS OF NACL CONCENTRATION ON THE BLEOMYCIN DNA INTERACTION	0	1
3757	1	20	986 1992 JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY 13(1):29-37 ITO Y; MIYACHI S PHOTOCHEMICAL RELEASE OF BASES FROM NUCLEOSIDES AND THEIR DERIVATIVES BY WATER-SOLUBLE IRON(III) PORPHYRINS	1	1
3758	2	28	1108 1993 BIOCONJUGATE CHEMISTRY 4(2):127-133 ITO Y PHOTODEGRADATION OF THE CYTOSINE NUCLEOSIDES FAMILY BY WATER-SOLUBLE IRON(III) PORPHYRINS	0	1
3759	4	19	1333 1994 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 4(5):705-710 SUGIYAMA T; OHNO M; SHIBASAKI M; OTSUKA M; SUGIURA Y; et al. ON THE MECHANISM OF ENZYMATIC INACTIVATION OF BLEOMYCIN - THE BETA-AMINOALANINAMIDE MOIETY AS AN ENZYME-DEPENDENT MOLECULAR SWITCH	1	1
3760	2	26	1395 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(45):27932-27940 PORTER DJT REACTION OF 5-ETHYNYLURACIL WITH RAT-LIVER XANTHINE-OXIDASE	0	1
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3761	1	15	1478 1994 SPECTROSCOPY LETTERS 27(6):787-799 LEE HH; KUWAE A; HANAI K STRUCTURE OF 3-PHENYL-2-THIOPYRUVIC ACID AS STUDIED BY FT-IR, FT-RAMAN, AND NMR SPECTROSCOPIES	0	1
3762	2	11	1492 1994 TETRAHEDRON LETTERS 35(40):7469-7472 FRAME AS; MACKENZIE G; WIGHTMAN RH SYNTHESIS OF 5-AMINO-4-SULFONAMIDOIMIDAZOLE NUCLEOSIDES AS POTENTIAL INHIBITORS OF PURINE BIOSYNTHESIS, AND OF AN IMIDAZOTHIADIAZINE DIOXIDE ANALOG OF ADENOSINE	1	1
3763	4	18	1506 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 317(1):285-291 SINHABABU AK; BOEHLERT CC; GAN LS; YANNI SB; THAKKER DR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC PURIFICATION, OPTIMIZATION OF THE ASSAY, AND PROPERTIES OF RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE FROM RABBIT BONE-MARROW	0	1
3764	3	26	1578 1995 CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE 73(6):878-884 CHANG DK; CHENG SF; CHIEN TL MOLECULAR MECHANICS CALCULATIONS ON THE COMPLEXES BETWEEN ANALOGS OF HOECHST-33258 AND D(CGCGAATTCGCG)(2) - INFLUENCE OF BULKY GROUP SUBSTITUTION ON BASE-PAIR PREFERENCE OF DNA MINOR-GROOVE BINDERS	0	1
3765	2	6	1584 1995 CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 16(3):410-412 WANG ZC; HUANG DY; YUAN JM THE EFFECT OF DIVALENT METAL-IONS ON THE INTERACTION BETWEEN PINGYANGMYCIN AND DNA	0	1
3766	8	58	1588 1995 CHEMIE IN UNSERER ZEIT 29(5):260-271 STEINBUCHEL A MICROBIAL AND CHEMICAL SYNTHESIS OF BIODEGRADABLE POLYESTERS	1	1
3767	0	0	1608 1995 FASEB JOURNAL 9(6):A1320-A1320 LICHT SS; STUBBE J EVIDENCE FOR THIYL RADICAL FORMATION IN RIBONUCLEOTIDE REDUCTASE	0	1
3768	11	43	1615 1995 HETEROCYCLES 41(6):1181-1196 HUANG L; LOWN JW SYNTHESIS OF DESIGNED FUNCTIONAL MODELS OF BLEOMYCIN INCORPORATING IMIDAZOLE-CONTAINING LEXITROPSINS AS NOVEL DNA RECOGNITION SITES	1	1
3769	5	194	1673 1995 JOURNAL OF SCIENTIFIC & INDUSTRIAL RESEARCH 54(12):717-736 Kunjappu JT; Venkatachalam SR; Nair CKK Interaction of molecules with DNA	0	1
3770	5	30	1725 1995 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (10):1259-1264 GUREVICH IE; TEBBY JC DIMETHYL 3-CHLOROPROP-1-EN-2-YLPHOSPHONATE .2. ALKYLATION OF AMINES, PHOSPHINES AND PHOSPHITES	0	1
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3771	3	20	1728 1995 KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII (10):1323-1331 Ramsden CA 5-Aminoimidazole chemistry	2	1
3772	9	68	1730 1995 MECHANISTIC BIOINORGANIC CHEMISTRY 246:1-20 Thorp HH Understanding the mechanisms in bioinorganic chemistry	0	1
3773	9	85	1733 1995 MECHANISTIC BIOINORGANIC CHEMISTRY 246:265-301 Pecoraro VL; Gelasco A; Baldwin MJ Reactivity and mechanism of manganese enzymes - A modeling approach	0	1
3774	7	15	1812 1996 BIOCHEMISTRY 35(14):4485-4491 McFarlan SC; Ong SP; Hogenkamp HPC Mechanism-based inhibition of ribonucleoside diphosphate reductase from Corynebacterium nephridii by 2'-C-methyladenosine diphosphate	0	1
3775	9	38	1835 1996 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1292(2):324-334 Latham KA; Rajendran S; Carmical JR; Lee JC; Lloyd RS T4 endonuclease V exists in solution as a monomer and binds to target sites as a monomer	0	1
3776	9	21	1847 1996 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 6(7):889-892 Gravert DJ; Griffin JH Similarities and differences in the DNA binding/cleaving specificities and mechanisms of [SalenMn(III)](+) and [TMPPMn(III)](5+)	0	1
3777	23	55	1861 1996 BULLETIN OF THE KOREAN CHEMICAL SOCIETY 17(12):1127-1131 Kim E; Lee KB; Jang HG Dioxygen binding to the singly alkoxo-bridged diferrous complex: Properties of [Fe-2(II)(N-Et-HPTB)Cl-2]BPh(4)	1	1
3778	6	33	1955 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(46):29121-29125 Holloway DE; Chen HP; Marsh ENG Carboxymethylation of MutS-cysteine-15 specifically inactivates adenosylcobalamin-dependent glutamate mutase - Examination of the role of this residue in coenzyme-binding and catalysis	1	1
3779	3	26	2019 1996 KRISTALLOGRAFIYA 41(2):293-304 Levdikov VM; Grebenko AI; Barynin VV; MelikAdamyan VR; Lamzin VS; et al. Three-dimensional structure of SAICAR-synthase from the Saccharomyces cerevisiae yeast at 1.9 angstrom resolution	0	1
3780	2	43	2042 1996 ONCOLOGY REPORTS 3(1):191-195 Hahn KA; Barnhill MA Effect of hypoxia on the frequency of bleomycin-induced micronuclei.	0	1
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3781	2	23	2059 1996 RUSSIAN JOURNAL OF APPLIED CHEMISTRY 69(5):654-658 Belyaev AN; Simanova SA; Matasov VB; Shchukarev AV Reaction of trinuclear chromium(III,III,III) mu(3)-oxoacetate with alpha-picoline yielding binuclear chromium(III,III) mu-oxoacetate	0	1
3782	1	8	2062 1996 SCIENCE 274(5290):1152-1153 Stubbe J Natural products - One of nature's macromolecular machines demystified	1	1
3783	3	28	2071 1996 TETRAHEDRON 52(27):9219-9236 Frame AS; Wightman RH; Mackenzie G Synthesis of 5-amino-4-sulfonamidoimidazole nucleosides as potential inhibitors of purine nucleotide biosynthesis, and of an imidazothiadiazine dioxide analogue of adenosine	0	1
3784	1	54	2149 1997 BIOSPECTROSCOPY 3(3):171-181 Bienkiewicz EA; Woody RW Reexamination of the structural characteristics of the acyl carrier protein	0	1
3785	8	9	2169 1997 CHIMIA 51(3):93-94 Marx A; Giese B Selective action of 4'-benzoylated thymidine on DNA polymerases and reverse transcriptases	0	1
3786	3	237	2173 1997 CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY 27(4):319-382 Kovacs PE; Valentine RL; Alvarez PJJ The effect of static magnetic fields on biological systems: Implications for enhanced biodegradation	0	1
3787	9	33	2192 1997 GENERAL PHARMACOLOGY 29(5):701-706 Nocentini G; Barzi A Antitumor activity of 2,2'-bipyridyl 6-carbothioamide: A ribonucleotide reductase inhibitor	0	1
3788	1	4	2205 1997 JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG 339(1):96-97 Mensching S; Kalesse M Generation of thiazoles by column dehydrogenation of thiazolidines with MnO2	0	1
3789	1	15	2206 1997 JOURNAL OF BACTERIOLOGY 179(2):563-566 White RH Occurrence and biosynthesis of 5-aminoimidazole-4-carboxamide ribonucleotide and N-(beta-D-ribofuranosyl)formamide 5'-phosphate in Methanobacterium thermoautotrophicum Delta H	0	1
3790	3	35	2245 1997 JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 104(1-3):97-104 Berthod T; Cadet J; Molko D 5-carboxy-2'-deoxyuridine, a new photooxidation product of thymidine	0	1
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3791	3	26	2295 1997 KINETICS AND CATALYSIS 38(2):253-257 Kulikova VS; Geletii YV Modeling of mononuclear nonheme Fe(II) monooxygenase: Study of hydroxylating characteristics of the Fe(cyclame)(otf)(2) complex with iodosylbenzene	0	1
3792	3	32	2328 1997 POLISH JOURNAL OF CHEMISTRY 71(11):1511-1517 Li YT; Yan CW; Liao DZ Synthesis, spectral and magnetic properties of mu-chloranilato manganese(II) binuclear complexes	0	1
3793	4	22	2342 1997 SEMINARS IN ONCOLOGY 24(2):S24-S28 Lawrence TS; Eisbruch A; Shewach DS Gemcitabine-mediated radiosensitization	0	1
3794	5	12	2365 1998 ACTA BIOCHIMICA POLONICA 45(1):13-18 Guenther R; Forrest B; Newman W; Malkiewicz A; Agris PF Modified RNAs as potential drug targets	0	1
3795	2	13	2369 1998 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 54:281-283 Montoya G; Svensson C; Savage H; Schwenn JD; Sinning I Crystallization and preliminary X-ray diffraction studies of phospho-adenylylsulfate (PAPS) reductase from E-coli	0	1
3796	10	40	2421 1998 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1382(1):102-110 White PW Understanding the molecular mechanism of viral resistance to peptidomimetic inhibitors of ribonucleotide reductase	0	1
3797	8	19	2435 1998 CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE 76(3):260-264 Shinozuka K; Kohda J; Sawai H Oxidation of olefins catalyzed by iron complexes of bleomycin model compounds bearing a hydrophobic or hydrophilic steric factor	0	1
3798	6	31	2483 1998 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (11):2417-2423 Wolf J; Monneret C; Pontikis R; Florent JC New synthetic routes for the preparation of 2 '-C-methylene nucleosides	0	1
3799	14	47	2509 1998 INORGANIC CHEMISTRY COMMUNICATIONS 1(2):71-76 Cai LS; Han Y; Mahmoud H; Xie WG; Segal BM Preorganization of iron centers for the activation of molecular dioxygen	1	1
3800	2	15	2632 1998 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 25(5):407-413 Ma WJ; Cao EH Phenanthroline-Cu complex induced DNA damage and its study as a chemical nuclease.	0	1
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3801	2	29	2643 1998 SYNTHESIS AND REACTIVITY IN INORGANIC AND METAL-ORGANIC CHEMISTRY 28(8):1283-1297 Li YT; Yan CW Synthesis, characterization and magnetic properties of chloranilato-bridged iron(III) binuclear complexes	0	1
3802	3	26	2648 1998 TRANSITION METAL CHEMISTRY 23(3):245-248 Li YT; Yan CW; Liao DZ Synthesis and magnetic properties of chloroanilato-bridged manganese(II) binuclear complexes	0	1
3803	9	13	2652 1998 ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES 53(9-10):867-870 Kobayashi T; Guo LL; Nishida Y Mechanism of double-strand DNA cleavage effected by iron-bleomycin	1	1
3804	3	17	2656 1999 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 55:518-521 Weaver TM; Wang WR; Ealick SE Purification, crystallization and preliminary X-ray diffraction data from selenomethionine glycinamide ribonucleotide synthetase	1	1
3805	1	27	2660 1999 ANALYTICAL BIOCHEMISTRY 266(1):85-92 Smiley JA; Angelot JM; Cannon RC; Marshall EM; Asch DK Radioactivity-based and spectrophotometric assays for isoorotate decarboxylase: Identification of the thymidine salvage pathway in lower eukaryotes	0	1
3806	2	26	2680 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 254(1):70-76 Gerloff DL; Cannarozzi GM; Joachimiak M; Cohen FE; Schreiber D; et al. Evolutionary, mechanistic, and predictive analyses of the hydroxymethyldihydropterin pyrophosphokinase family of proteins	0	1
3807	10	66	2720 1999 BIOORGANIC & MEDICINAL CHEMISTRY 7(11):2531-2540 Steullet V; Edwards-Bennett S; Dixon DW Cleavage of abasic sites in DNA by intercalator-amines	1	1
3808	17	69	2723 1999 BIOORGANIC CHEMISTRY 27(6):451-462 Suto RK; Poppe L; Retey J; Finke RG Ribonucleoside triphosphate reductase from Lactobacillus leichmannii: Kinetic evaluation of a series of adenosylcobalamin competitive inhibitors, [omega-(adenosin-5 '-O-yl)alkyl]cobalamins, which mimic the post Co-C homolysis intermediate	1	1
3809	4	17	2733 1999 CHEMICAL COMMUNICATIONS (13):1219-1220 Kumar CV; Asuncion EH Sequence dependent energy transfer from DNA to an anthryl probe: discrimination between GC and IC sequences	0	1
3810	3	58	2745 1999 COORDINATION CHEMISTRY REVIEWS 186:307-319 Supkowski RM; Bolender JP; Smith WD; Reynolds LEL; Horrocks WD Lanthanide ions as redox probes of long-range electron transfer in proteins	0	1
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3811	4	43	2764 1999 HELVETICA CHIMICA ACTA 82(8):1250-1265 Poppe L; Hull WE; Nitsche R; Graf T; Stupperich E; et al. (Hydroxyalkyl)cob(III)alamins as competitive inhibitors in coenzyme B-12-dependent enzymic reactions: H-1-NMR structure analysis and kinetic studies with glycerol dehydratase and diol dehydratase	0	1
3812	4	19	2788 1999 INTERNATIONAL JOURNAL OF ONCOLOGY 15(3):487-490 Crenshaw TR; Cory JG Mouse leukemia L1210 cells selected for resistance to the ribonucleotide reductase inhibitor, 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone show altered response to DNA damaging agents	0	1
3813	3	12	2793 1999 JOURNAL OF ANTIBIOTICS 52(10):895-899 Sugiyama M; Tanaka M; Kumagai T A mammalian vector carrying the bleomycin N-acetyltransferase gene from bleomycin-producing Streptomyces verticillus as a selective marker	1	1
3814	2	38	2824 1999 JOURNAL OF BIOTECHNOLOGY 68(1):49-60 Jackson JK; Srienc F Effects of recombinant modulation of the phbCAB operon copy number on PHB synthesis rates in Ralstonia eutropha	1	1
3815	3	20	2827 1999 JOURNAL OF ENVIRONMENTAL POLYMER DEGRADATION 7(4):179-184 Bear MM; Mallarde D; Langlois V; Randriamahefa S; Bouvet O; et al. Natural and artificial functionalized biopolyesters. II. Medium-chain length polyhydroxyoctanoates from Pseudomonas strains	0	1
3816	3	23	2840 1999 JOURNAL OF MAGNETIC RESONANCE 141(2):291-300 Song RT; Doan PE; Gurbiel RJ; Sturgeon BE; Hoffman BM Non-Kramers ENDOR and ESEEM of the S=2 ferrous ion of [Fe(II)EDTA](2-)	1	1
3817	10	42	2847 1999 JOURNAL OF ORGANIC CHEMISTRY 64(5):1559-1564 Korner S; Bryant-Friedrich A; Giese B C-3 '-branched thymidines as precursors for the selective generation of C-3 '-nucleoside radicals	0	1
3818	8	31	2888 1999 JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS (13):2205-2210 Horng DN; Lee KM Using pseudohalides (NCS-, N-3(-)) as a probe for the active site of (mu-alkoxo)diiron(III) complexes and to reveal a novel asymmetrical structure	0	1
3819	1	327	2913 1999 NACHRICHTEN AUS CHEMIE TECHNIK UND LABORATORIUM 47(2):186-195 Marx D Theoretical chemistry 1998	0	1
3820	4	8	2920 1999 NUCLEOSIDES & NUCLEOTIDES 18(4-5):611-612 Magnin GC; Dauvergne J; Burger A; Biellmann JF Synthesis of a C-8 modified adenosine analogue as a potential mechanistic probe for ribonucleotide reductases.	0	1
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3821	8	31	2964 2000 ACTA BIOCHIMICA POLONICA 47(1):165-171 Grieb P; Koronkiewicz M; Skierski JS Cytostatic and cytotoxic effects of (E)-2 '-deoxy-2 '- (fluoromethylene)-cytidine on a solid tumor and a leukemia cell line	0	1
3822	7	37	3007 2000 BIOCHEMISTRY 39(43):13210-13215 Kawanishi S; Oikawa S; Kawanishi M; Sugiyama H; Saito I; et al. Amplification of pepleomycin-mediated DNA cleavage and apoptosis by unfused aromatic cations	0	1
3823	16	36	3028 2000 BIOPHYSICAL JOURNAL 79(4):2155-2161 Bolger G; Liuzzi M; Krogsrud R; Scouten E; McCollum R; et al. Radiation inactivation of ribonucleotide reductase, an enzyme with a stable free radical	1	1
3824	3	10	3030 2000 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 64(9):1836-1841 Brunella A; Abrantes M; Ghisalba O Preparative 2 '-reduction of ATP catalyzed by ribonucleotide reductase purified by liquid-liquid extraction	0	1
3825	5	55	3061 2000 COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 169(1-3):47-58 Ariga K; Tanaka K; Katagiri K; Kikuchi J; Ohshima E; et al. Syntheses and monolayer properties of vitamin B-12 derivatives with seven alkyl chains	0	1
3826	2	6	3071 2000 CURRENT OPINION IN STRUCTURAL BIOLOGY 10(6):709-710 Stubbe J; Johnson LN Clarity through structures	2	1
3827	8	50	3086 2000 GENETICS 154(3):1239-1253 O'Donnell AF; Tiong S; Nash D; Clark DV The Drosophila melanogaster ade5 gene encodes a bifunctional enzyme for two steps in the de novo purine synthesis pathway	0	1
3828	5	49	3093 2000 INORGANIC CHEMISTRY 39(8):1823-1827 Wang KF; Jordan RB Complexation of Co(DBP2)(2) by N-methylimidazole in acetonitrile: Formation constants and H-1 NMR shifts and relaxation times	0	1
3829	7	11	3102 2000 INORGANIC CHEMISTRY COMMUNICATIONS 3(11):608-610 Kobayashi T; Nishino S; Masuda H; Einaga H; Nishida Y Detection of complex formation between binuclear iron(III)-peroxide adduct and oligonucleotide by electrospray mass spectrometry	0	1
3830	2	13	3104 2000 INORGANICA CHIMICA ACTA 297(1-2):400-403 Doan PE; Hoffman BM How important is parallel-mode EPR in electron spin echo envelope modulation studies of non-Kramers systems?	1	1
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3831	2	19	3105 2000 INORGANICA CHIMICA ACTA 298(1):38-42 Mialane P; Girerd JJ; Guilhem J; Tchertanov L Synthesis and structure of a new iron(III) complex with a doubly positively charged ligand. Oxidative study of the related catecholato adduct	0	1
3832	7	52	3107 2000 INORGANICA CHIMICA ACTA 300:762-768 Sixt T; Kaim W Copper(I) complexes with N,O-donor Schiff base ligands related to intermediate forms of the TPQ cofactor in amine oxidases	0	1
3833	10	60	3134 2000 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS :285-291 Rajski SR; Barton JK DNA-mediated electron transfer: A sensitive probe of DNA-protein interactions	0	1
3834	28	43	3142 2000 JOURNAL OF INORGANIC BIOCHEMISTRY 80(3-4):213-218 Davydov A; Liu AM; Graslund A EPR evidence of two structurally different diferric sites in Mycobacterium tuberculosis R2-2 ribonucleotide reductase protein	1	1
3835	16	30	3241 2000 POLYHEDRON 19(26-27):2639-2648 Kobayashi T; Kunita M; Nishino S; Matsushima H; Tokii T; et al. Release of free nucleobases from oligomers by copper(II)-peroxide adduct	0	1
3836	21	36	3254 2000 TETRAHEDRON LETTERS 41(20):3919-3922 Ikeda S; Saito I; Sugiyama H Metallo-bleomycin cleaves parallel-stranded DNA similarly to B-DNA	1	1
3837	3	10	3263 2001 ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE 57:m315-m317 Daly RI; Taylor MR; Martin LL Acetonitrile{N-[2-(4,7-dimethyl-1,4,7-triazacyclonon-1-yl)ethyl]-N-[(1-methylbenzimidazol-2-yl)methyl]-methylamine}nickel(II) bis(perchlorate) acetonitrile solvate	0	1
3838	5	470	3265 2001 ADVANCES IN CLINICAL CHEMISTRY, VOL 35 35:161-253 Naskalski JW; Bartosz G Oxidative modifications of protein structures	0	1
3839	17	408	3266 2001 ADVANCES IN PHYSICAL ORGANIC CHEMISTRY, VOL 36 36:1-58 Tidwell TT The Gomberg century: Free radicals 1900-2000	0	1
3840	11	35	3291 2001 BIOCHEMICAL PHARMACOLOGY 61(3):351-356 Hiraku Y; Oikawa S; Kuroki K; Sugiyama H; Saito I; et al. Amplification of bleomycin-induced DNA cleavage at cytosine residues 3 ' to GGG sequences by pyrrole triamide	0	1
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3841	4	14	3332 2001 BIOTECHNOLOGY LETTERS 23(24):2057-2061 Sim SJ; Snell KD; Kim BW; Rha CK; Sinskey AJ Increased poly-beta-hydroxybutyrate (PHB) chain length by the modulation of PHA synthase activity in recombinant Escherichia coli	1	1
3842	1	31	3363 2001 CYTOGENETICS AND CELL GENETICS 94(1-2):55-61 Mrug M; Green WJ; DasGupta S; Beier DR; Lu W; et al. An integrated genetic and physical map of the 650-kb region containing the congenital polycystic kidney (cpk) locus on mouse Chromosome 12	0	1
3843	15	79	3364 2001 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 37(2):117-127 Hoffmann GR; Buccola J; Merz MS; Littlefield LG Structure-activity analysis of the potentiation by aminothiols of the chromosome-damaging effect of bleomycin in G(0) human lymphocytes	0	1
3844	1	25	3370 2001 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 36(6):561-568 Tamburlin-Thumin I; Crozet MP; Barriere JC; Barreau M; Riou JF; et al. Synthesis and biological evaluation of O-alkylated tropolones and related alpha-ketohydroxy derivatives as ribonucleotide reductase inhibitors	0	1
3845	2	36	3433 2001 JOURNAL OF HEPATOLOGY 34(1):108-113 Chouteau P; Le Seyec J; Saulier-Le Drean B; Cannie T; Brissot P; et al. Inhibition of hepatitis B virus production associated with high levels of intracellular viral DNA intermediates in iron-depleted HepG2.2.15 cells	0	1
3846	0	0	3436 2001 JOURNAL OF INORGANIC BIOCHEMISTRY 86(1):92-92 Rosenzweig AC; Lamb AL; Voegtli WC; Ge J; Perlstein DL; et al. Heterodimeric mechanisms of metal cofactor assembly	1	1
3847	1	1	3442 2001 JOURNAL OF INORGANIC BIOCHEMISTRY 86(1):294-294 Kimura S; Bothe E; Bill E; Weyhermuller T; Wieghardt K New thiyl and phenoxyl radical complexes	0	1
3848	2	35	3446 2001 JOURNAL OF MAGNETIC RESONANCE 149(1):67-73 Fuhs M; Prisner T; Mobius K Fourier-transform EPR at high-field/high-frequency (3.4 T/95 GHz) using broadband stochastic microwave excitation	0	1
3849	17	23	3491 2001 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 123(50):12742-12743 Lukoyanov D; Burger RM; Scholes CP ENDOR determination of the distance between bleomycin-bound iron and F-19 of 2 '-fluorocytidine in a DNA target sequence	1	1
3850	20	410	3512 2001 NATURAL PRODUCT REPORTS 18(5):465-493 Bugg TDH The development of mechanistic enzymology in the 20th century	0	1
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3851	18	46	3535 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(18):10067-10072 Ge H; Perlstein DL; Nguyen HH; Bar G; Griffin RG; et al. Why multiple small subunits (Y2 and Y4) for yeast ribonucleotide reductase? Toward understanding the role of Y4	1	1
3852	9	34	3538 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(23):12863-12865 Xie LL; van der Donk WA Homemade cofactors: Self-processing in galactose oxidase	0	1
3853	8	47	3586 2002 BIOCHEMICAL JOURNAL 365:547-553 Shatilla A; Ramotar D Embryonic extracts derived from the nematode Caenorhabditis elegans remove uracil from DNA by the sequential action of uracil-DNA glycosylase and AP (apurinic/apyrimidinic) endonuclease	0	1
3854	2	43	3587 2002 BIOCHEMICAL JOURNAL 365:833-840 Cioffi AV; Ferrara D; Cubellis MV; Aniello F; Corrado M; et al. An open reading frame in intron seven of the sea urchin DNA-methyltransferase gene codes for a functional AP1 endonuclease	0	1
3855	1	21	3589 2002 BIOCHEMICAL PHARMACOLOGY 64(3):451-456 Fagny C; Vandevelde M; Svoboda M; Robberecht P Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide	0	1
3856	15	25	3615 2002 BIOCHEMISTRY 41(52):15803-15809 Madhavapeddi P; Ballou DP; Marsh ENG Pre-steady-state kinetic studies on the Glu171Gln active site mutant of adenosylcobalamin-dependent glutamate mutase	1	1
3857	14	27	3626 2002 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 12(2):201-203 Kurosaki H; Maruyama A; Koike H; Kuroda N; Ishikawa Y; et al. DNA cleavage by pentadentate iron(II) complexes containing fluoro-substituted phenyl groups	0	1
3858	4	38	3637 2002 CANCER CHEMOTHERAPY AND PHARMACOLOGY 50(5):353-359 Yen Y; Chow W; Leong L; Margolin K; Morgan R; et al. Phase I pharmacodynamic study of time and sequence dependency of hydroxyurea in combination with gemcitabine: a California Cancer Consortium Trial	0	1
3859	1	26	3653 2002 CURRENT GENETICS 41(1):20-24 Kucej M; Kosa P; Adamikova L; Nosek J Isolation of genes coding for Ade2 and Ura3 homologues from the multinuclear yeast Dipodascus magnusii	0	1
3860	6	241	3668 2002 ENZYME KINETICS AND MECHANISM, PT F: DETECTION AND CHARACTERIZATION OF ENZYME REACTION INTERMEDIATES 354:455-470 Allison RD; Purich DL A survey of covalent, ionic, and radical intermediates in enzyme-catalyzed reactions	0	1
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3861	26	52	3670 2002 EUROPEAN JOURNAL OF BIOCHEMISTRY 269(13):3226-3236 Garcia-Alles LF; Erni B Synthesis of phosphoenolpyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes	1	1
3862	3	36	3677 2002 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 37(3):207-217 Hakimelahi GH; Moosavi-Movahedi AA; Sambaiah T; Zhu JL; Ethiraj KS; et al. Reactions of purines-containing butenolides with L-cysteine or N-acetyl-L-cysteine as model biological nucleophiles: a potent mechanism-based inhibitor of ribonucleotide reductase caused apoptosis in breast carcinoma MCF7 cells	0	1
3863	8	32	3688 2002 INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY 41(1):65-72 Cowan JA An inorganic approach to drug design: Novel inorganic nucleases	0	1
3864	5	11	3694 2002 INORGANIC CHEMISTRY COMMUNICATIONS 5(8):609-611 Nishino S; Takahashi Y; Nishida Y Important role of hydrogen peroxide for storing of iron ions in human L-subunit ferritin	0	1
3865	16	40	3698 2002 INORGANICA CHIMICA ACTA 337:83-90 Liu AM; Leese DN; Swarts JC; Sykes AG Reduction of Escherichia coli ribonucleotide reductase subunit R2 with eight water-soluble ferrocene derivatives	0	1
3866	19	45	3701 2002 INORGANICA CHIMICA ACTA 340:170-180 Kong DY; Reibenspies J; Mao JG; Martell AE; Clearfield A Syntheses, systematic potentiometry and structural studies of 26-membered hexaaza-diphenolate-based macrocyclic diiron complexes	0	1
3867	3	42	3703 2002 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 31(1-3):63-69 Ramachander TVN; Rohini D; Belhekar A; Rawal SK Synthesis of PHB by recombinant E. coli harboring an approximately 5 kb genomic DNA fragment from Streptomyces aureofaciens NRRL 2209	0	1
3868	2	28	3705 2002 INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY 87(3):152-157 Kang CM; Feng DC; Qi CS; Zhao WA; Cai ZT Comparative study of folate cofactor models	0	1
3869	3	201	3706 2002 JOURNAL OF APPLIED POLYMER SCIENCE 83(3):457-483 Asrar J; Hill JC Biosynthetic processes for linear polymers	0	1
3870	15	33	3714 2002 JOURNAL OF BIOCHEMISTRY 132(6):935-943 Fukuoka M; Yamada S; Miyoshi S; Yamashita K; Yamanishi M; et al. Functions of the D-ribosyl moiety and the lower axial ligand of the nucleotide loop of coenzyme B-12 in diol dehydratase and ethanolamine ammonia-lyase reactions	1	1
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3871	18	37	3742 2002 JOURNAL OF INORGANIC BIOCHEMISTRY 90(1-2):8-17 Li WB; Antholine WE; Petering DH Kinetics of reaction of DNA-bound Fe(III)bleomycin with ascorbate: interplay of specific and non-specific binding	1	1
3872	4	36	3745 2002 JOURNAL OF INORGANIC BIOCHEMISTRY 91(2):388-397 Doll KM; Fleming PE; Finke RG The synthesis and characterization of 8-methoxy-5 '- deoxyadenosylcobalamin: a coenzyme B-12 analog which, following Co-C bond homolysis, avoids cyclization of the 8-methoxy-5 '-deoxyadenosyl radical	1	1
3873	3	7	3746 2002 JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 45(13):1097-1102 Mehl RA; Begley TP Synthesis of P-32-labeled intermediates on the purine biosynthetic pathway	0	1
3874	2	19	3747 2002 JOURNAL OF MAGNETIC RESONANCE 155(1):100-105 Shubin AA; Dikanov SA Determination of hyperfine tensor components from nuclear frequencies at canonical orientations of the g-tensor	1	1
3875	3	49	3778 2002 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 124(15):4108-4115 Petucci C; Nyman M; Guler L; Kenttamaa H Hydrogen atom abstraction reactions of charged polyaromatic sigma-radicals related to the active intermediates of the enediyne antitumor drugs	0	1
3876	1	27	3830 2002 POLYHEDRON 21(2):155-165 Royer AC; Rogers RD; Arrington DL; Street SC; Vincent JB Spectroscopic studies of the dodecanuclear chromium complex Cr12O9(OH)(3)(pivalate)(15): confirmation of the presence of twelve Cr(III) centers and the crystal structure of Cr12O9(OH)(3)(pivalate)(15)center dot 2PrOH center dot 9H(2)O	0	1
3877	22	42	3838 2002 PROTEIN SENSORS AND REACTIVE OXYGEN SPECIES, PT B, THIOL ENZYMES AND PROTEINS 348:21-30 Fontecave M; Gerez C Tyrosyl radicals and ribonucleotide reductase	0	1
3878	10	37	3850 2002 SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 58(6):1191-1200 Deligiannakis Y; Ivancich A; Rutherord AW 2D-hyperfine sublevel correlation spectroscopy of tyrosyl radicals	0	1
3879	1	30	3853 2002 SYNTHETIC COMMUNICATIONS 32(14):2125-2135 Marson CM; Decreau RA; Smith KE Preparation of 3 alpha-Fluoro-and 3 beta-Fluoro derivatives of 5 alpha-androst-16-enes and androsta-5,16-dienes	0	1
3880	3	51	3869 2003 ADVANCES IN ENVIRONMENTAL RESEARCH 7(2):583-595 Rodriguez ML; Timokhin VI; Contreras S; Chamarro E; Esplugas S Rate equation for the degradation of nitrobenzene by 'Fenton-like' reagent	0	1
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3881	15	37	3870 2003 ADVANCES IN ENZYME REGULATION, VOL 43 43:167-182 Cooperman BS; Kashlan OB A comprehensive model for the allosteric regulation of Class Ia ribonucleotide reductases	1	1
3882	2	29	3875 2003 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 42(9):1026-+ Largeron M; Neudorffer A; Fleury MB Oxidation of unactivated primary aliphatic amines catalyzed by an electrogenerated 3,4-azaquinone species: A small-molecule mimic of amine oxidases	0	1
3883	6	44	3884 2003 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 62(2-3):244-255 Kabir MM; Shimizu K Fermentation characteristics and protein expression patterns in a recombinant Escherichia coli mutant lacking phosphoglucose isomerase for poly(3-hydroxybutyrate) production	0	1
3884	3	45	3909 2003 BIODRUGS 17(3):169-177 Daifuku R Stealth nucleosides - Mode of action and potential use in the treatment of viral diseases	0	1
3885	4	35	3910 2003 BIOLOGICAL & PHARMACEUTICAL BULLETIN 26(8):1108-1114 Sugihara N; Kaneko A; Furuno K Oxidation of flavonoids which promote DNA degradation induced by bleomycin-Fe complex	0	1
3886	3	26	3912 2003 BIOORGANIC & MEDICINAL CHEMISTRY 11(20):4303-4313 Moosavi-Movahedi AA; Hakimelahi S; Chamani J; Khodarahmi GA; Hassanzadeh F; et al. Design, synthesis, and anticancer activity of phosphonic acid diphosphate derivative of adenine-containing butenolide and its water-soluble derivatives of paclitaxel with high antitumor activity	0	1
3887	27	54	3913 2003 BIOORGANIC & MEDICINAL CHEMISTRY 11(23):5179-5187 Cagir A; Tao ZF; Sucheck SJ; Hecht SM Solid-phase synthesis and biochemical evaluation of conformationally constrained analogues of deglycobleomycin A(5)	0	1
3888	1	12	3916 2003 BIOTECHNIQUES 34(5):908-909 Li GD; Shimelis O; Zhou XJ; Giese RW Scaled-down nuclease P1 for scaled-up DNA digestion	0	1
3889	3	30	3919 2003 BIOTECHNOLOGY AND BIOENGINEERING 84(1):114-120 Srinivasan S; Barnard GC; Gerngross TU Production of recombinant proteins using multiple-copy gene integration in high-cell-density fermentations of Ralstonia eutropha	1	1
3890	5	19	3920 2003 BIOTECHNOLOGY LETTERS 25(15):1243-1249 Seo MC; Shin HD; Lee YH Functional role of granule-associated genes, phaP and phaR, in poly-beta-hydroxybutyrate biosynthesis in recombinant E-coli harboring phbCAB operon	1	1
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3891	11	51	3922 2003 CANCER CHEMOTHERAPY AND PHARMACOLOGY 52(4):325-332 Ostruszka LJ; Shewach DS The role of DNA synthesis inhibition in the cytotoxicity of 2 ',2 '- difluoro-2 '-deoxycytidine	1	1
3892	2	76	3923 2003 CANCER RESEARCH 63(19):6229-6236 Lee WP; Tai DI; Tsai SL; Yeh CT; Chao Y; et al. Adenovirus type 5 E1A sensitizes hepatocellular carcinoma cells to gemcitabine	0	1
3893	5	10	3925 2003 CELL 112(3):286-287 Cox MM Better chemistry for better survival, through regulation	0	1
3894	5	14	3930 2003 CHEMICAL PHYSICS LETTERS 372(1-2):183-186 Chiavarino B; Crestoni ME; Fornarini S Gas phase regioselectivity in the deprotonation of p-cresol radical cation	0	1
3895	6	41	3932 2003 CHEMICAL RESEARCH IN TOXICOLOGY 16(9):1056-1061 Nauser T; Schoneich C Thiyl radical reaction with thymine: Absolute rate constant for hydrogen abstraction and comparison to benzylic C-H bonds	0	1
3896	6	47	3946 2003 CHEMISTRY-A EUROPEAN JOURNAL 9(15):3492-3500 Uyemura M; Aida T Characteristics of organic transformations in a confined dendritic core: Studies on the AMN-initiated reaction of dendrimer cobalt(II) porphyrins with alkynes	0	1
3897	19	66	3959 2003 CURRENT OPINION IN MICROBIOLOGY 6(3):251-260 Luengo JM; Garcia B; Sandoval A; Naharro G; Olivera ER Bioplastics from microorganisms	1	1
3898	3	21	3968 2003 ELECTROCHEMISTRY COMMUNICATIONS 5(1):6-11 Webster RD In situ electrochemical-ATR-FTIR spectroscopic studies on solution phase 2,4,6-tri-substituted phenoxyl radicals	0	1
3899	4	60	3972 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(22):4403-4412 Ghibaudi E; Laurenti E Unraveling the catalytic mechanism of lactoperoxidase and myeloperoxidase - A reflection on some controversial features	0	1
3900	11	55	3974 2003 EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (10):1956-1965 Mukherjee S; Weyhermuller T; Bothe E; Chaudhuri P Structural, magnetochemical and electrochemical studies of dinuclear complexes containing the [(VO)-O-V](2), [(VO)-O-IV](2), Cr-2(III), Mn-2(III) and Fe-2(III) cores of a potentially pentadentate phenol-containing ligand with (O,N,O,N,O)-donor atoms	0	1

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