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Nodes: 216,
Authors: 651,
Journals: 97,
Outer References: 4850,
Words: 668
Collection span: 1981 - 2005
View: Overview. Sorted by year, source, volume, issue, page.
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 0 | 0 | 1 1981 IN VITRO-JOURNAL OF THE TISSUE CULTURE ASSOCIATION 17(3):254-254 RHEINWALD JG REPLICATIVE SENESCENCE AND TERMINAL DIFFERENTIATION IN CULTURED-CELLS - THEIR RELATION TO AGING AND CANCER | 0 | 0 |
| 2 | 0 | 20 | 2 1989 EXPERIMENTAL CELL RESEARCH 184(1):138-147 WEST MD; PEREIRASMITH OM; SMITH JR REPLICATIVE SENESCENCE OF HUMAN-SKIN FIBROBLASTS CORRELATES WITH A LOSS OF REGULATION AND OVEREXPRESSION OF COLLAGENASE ACTIVITY | 11 | 112 |
| 3 | 0 | 31 | 3 1989 EXPERIMENTAL CELL RESEARCH 184(1):256-261 HOUDE M; REIS RJS; GOLDSTEIN S PROPORTIONS OF H-1 HISTONE SUBSPECIES IN HUMAN-FIBROBLASTS SHIFT DURING DENSITY-DEPENDENT GROWTH ARREST INDEPENDENT OF REPLICATIVE SENESCENCE | 0 | 4 |
| 4 | 0 | 25 | 4 1989 EXPERIMENTAL GERONTOLOGY 24(5-6):461-468 GOLDSTEIN S; MURANO S; BENES H; MOERMAN EJ; JONES RA; et al. STUDIES ON THE MOLECULAR-GENETIC BASIS OF REPLICATIVE SENESCENCE IN WERNER SYNDROME AND NORMAL FIBROBLASTS | 3 | 22 |
| 5 | 0 | 57 | 5 1989 EXPERIMENTAL GERONTOLOGY 24(5-6):539-558 HORNSBY PJ; RYAN RF; CHENG CY REPLICATIVE SENESCENCE AND DIFFERENTIATED GENE-EXPRESSION IN CULTURED ADRENOCORTICAL-CELLS | 0 | 23 |
| 6 | 0 | 35 | 6 1989 JOURNAL OF CELL SCIENCE 94:757-& YANG LQ; HORNSBY PJ DISSOCIATION OF SENESCENCE-ASSOCIATED CHANGES IN DIFFERENTIATED GENE-EXPRESSION AND REPLICATIVE SENESCENCE IN CULTURED ADRENOCORTICAL-CELLS | 0 | 14 |
| 7 | 1 | 88 | 7 1990 SCIENCE 249(4973):1129-1133 GOLDSTEIN S REPLICATIVE SENESCENCE - THE HUMAN FIBROBLAST COMES OF AGE | 25 | 491 |
| 8 | 2 | 86 | 8 1991 MOLECULAR AND CELLULAR BIOLOGY 11(8):3905-3914 MURANO S; THWEATT R; REIS RJS; JONES RA; MOERMAN EJ; et al. DIVERSE GENE-SEQUENCES ARE OVEREXPRESSED IN WERNER SYNDROME FIBROBLASTS UNDERGOING PREMATURE REPLICATIVE SENESCENCE | 6 | 164 |
| 9 | 1 | 60 | 9 1992 EXPERIMENTAL CELL RESEARCH 202(1):161-166 IRVING J; FENG JL; WISTROM C; PIKAART M; VILLEPONTEAU B AN ALTERED REPERTOIRE OF FOS JUN (AP-1) AT THE ONSET OF REPLICATIVE SENESCENCE | 1 | 74 |
| 10 | 1 | 15 | 10 1992 EXPERIMENTAL GERONTOLOGY 27(4):425-428 MILLIS AJT; MCCUE HM; KUMAR S; BAGLIONI C METALLOPROTEINASE AND TIMP-1 GENE-EXPRESSION DURING REPLICATIVE SENESCENCE | 2 | 8 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 3 | 30 | 11 1992 EXPERIMENTAL GERONTOLOGY 27(4):433-440 THWEATT R; MURANO S; FLEISCHMANN RD; GOLDSTEIN S ISOLATION AND CHARACTERIZATION OF GENE-SEQUENCES OVEREXPRESSED IN WERNER SYNDROME FIBROBLASTS DURING PREMATURE REPLICATIVE SENESCENCE | 2 | 12 |
| 12 | 0 | 20 | 12 1993 CANCER RESEARCH 53(11):2469-2471 RIEBER MS; RIEBER M SPECIFIC TYROSINASES ASSOCIATED WITH MELANOMA REPLICATIVE SENESCENCE AND MELANOGENESIS | 0 | 4 |
| 13 | 2 | 33 | 13 1993 CELL BIOCHEMISTRY AND FUNCTION 11(4):263-269 PASSI A; ALBERTINI R; BARDONI A; RINDI S; SALVINI R; et al. MODIFICATIONS OF PROTEOGLYCANS PRODUCED BY HUMAN SKIN FIBROBLAST-CULTURES DURING REPLICATIVE SENESCENCE | 0 | 3 |
| 14 | 0 | 31 | 14 1993 CELL PROLIFERATION 26(1):45-54 WELLER EM; POOT M; HOEHN H INDUCTION OF REPLICATIVE SENESCENCE BY 5-AZACYTIDINE - FUNDAMENTAL CELL KINETIC DIFFERENCES BETWEEN HUMAN-DIPLOID FIBROBLASTS AND NIH-3T3 CELLS | 0 | 10 |
| 15 | 3 | 266 | 15 1993 PHYSIOLOGICAL REVIEWS 73(3):617-638 CRISTOFALO VJ; PIGNOLO RJ REPLICATIVE SENESCENCE OF HUMAN FIBROBLAST-LIKE CELLS IN CULTURE | 16 | 130 |
| 16 | 1 | 28 | 16 1994 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 59:67-73 DIMRI GP; CAMPISI J MOLECULAR AND CELL BIOLOGY OF REPLICATIVE SENESCENCE | 4 | 32 |
| 17 | 2 | 37 | 17 1994 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91(6):2186-2190 LIU S; THWEATT R; LUMPKIN CK; GOLDSTEIN S SUPPRESSION OF CALCIUM-DEPENDENT MEMBRANE CURRENTS IN HUMAN FIBROBLASTS BY REPLICATIVE SENESCENCE AND FORCED EXPRESSION OF A GENE SEQUENCE ENCODING A PUTATIVE CALCIUM-BINDING PROTEIN | 4 | 16 |
| 18 | 0 | 10 | 18 1995 AGING-CLINICAL AND EXPERIMENTAL RESEARCH 7(6):464-466 Effros RB Replicative senescence of T lymphocytes: Effect on immune function | 0 | 0 |
| 19 | 0 | 71 | 19 1995 AMERICAN JOURNAL OF PATHOLOGY 147(1):1-8 HENSLER PJ; PEREIRASMITH OM HUMAN REPLICATIVE SENESCENCE - A MOLECULAR STUDY | 0 | 21 |
| 20 | 0 | 0 | 20 1995 DIABETOLOGIA 38:A206-A206 MOROCUTTI A; SETHI M; EARLE K; VORA H; VIBERTI GC REPLICATIVE SENESCENCE IN CULTURED SKIN FIBROBLASTS FROM INSULIN-DEPENDENT DIABETIC-PATIENTS WITH NEPHROPATHY | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 0 | 0 | 21 1995 FASEB JOURNAL 9(3):A549-A549 HELENIUS M; HANNINEN M; LEHTINEN SK; SALMINEN A REGULATION OF NF-KB-COMPLEX DURING AGING AND REPLICATIVE SENESCENCE | 0 | 0 |
| 22 | 0 | 0 | 22 1995 FASEB JOURNAL 9(6):A1464-A1464 DIMRI GP; HARA E; ACOSTA M; DESPREZ P; CAMPISI J THE ROLE OF P53 TUMOR-SUPPRESSOR IN CELLULAR REPLICATIVE SENESCENCE | 0 | 0 |
| 23 | 0 | 0 | 23 1995 JOURNAL OF CELLULAR BIOCHEMISTRY :92-92 EFFROS RB; SCHACHTER F; BOUCHER N; SPAULDING C; ZHU XM; et al. LOSS OF CD28 EXPRESSION IS ASSOCIATED WITH REPLICATIVE SENESCENCE OF T-CELLS IN-VITRO AND IN-VIVO | 0 | 0 |
| 24 | 0 | 1 | 24 1995 SCIENCE 267(5194):17-17 LINSKENS MHK; HARLEY CB; WEST MD; CAMPISI J; HAYFLICK L REPLICATIVE SENESCENCE AND CELL-DEATH | 3 | 32 |
| 25 | 0 | 39 | 25 1996 AIDS 10(8):F17-F22 Effros RB; Allsopp R; Chiu CP; Hausner MA; Hirji K; et al. Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis | 15 | 160 |
| 26 | 1 | 28 | 26 1996 BIOCHEMICAL JOURNAL 318:603-608 Helenius M; Hanninen M; Lehtinen SK; Salminen A Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B | 1 | 55 |
| 27 | 2 | 35 | 27 1996 BIOLOGICAL SIGNALS 5(3):154-162 Dimri GP; Testori A; Acosta M; Campisi J Replicative senescence, aging and growth-regulatory transcription factors | 2 | 22 |
| 28 | 3 | 23 | 28 1996 CELL 84(4):497-500 Campisi J Replicative senescence: An old lives' tale? | 12 | 223 |
| 29 | 0 | 30 | 29 1996 EXPERIMENTAL GERONTOLOGY 31(1-2):13-19 Bernier L; Wang E A prospective view on phosphatases and replicative senescence | 0 | 4 |
| 30 | 1 | 48 | 30 1996 EXPERIMENTAL GERONTOLOGY 31(1-2):235-243 Allsopp RC Models of initiation of replicative senescence by loss of telomeric DNA | 2 | 11 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 2 | 79 | 31 1996 EXPERIMENTAL GERONTOLOGY 31(1-2):281-293 Howard BH Replicative senescence: Considerations relating to the stability of heterochromatin domains | 1 | 28 |
| 32 | 0 | 0 | 32 1996 MOLECULAR BIOLOGY OF THE CELL 7:36-36 Campisi J Replicative senescence, cancer and aging. | 0 | 0 |
| 33 | 0 | 0 | 33 1996 MOLECULAR BIOLOGY OF THE CELL 7:3107-3107 Helenius M; Makelainen L; Salminen A Photoaging: UVB-induced activation of transcription factor NF-kB and replicative senescence | 0 | 0 |
| 34 | 0 | 59 | 34 1996 ONCOGENE 13(3):561-568 Loughran O; Malliri A; Owens D; Gallimore PH; Stanley MA; et al. Association of CDKN2A/p16(INK4A) with human head and neck keratinocyte replicative senescence: Relationship of dysfunction to immortality and neoplasia | 9 | 93 |
| 35 | 1 | 37 | 35 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(24):13742-13747 Alcorta DA; Xiong Y; Phelps D; Hannon G; Beach D; et al. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts | 27 | 317 |
| 36 | 3 | 114 | 36 1996 SCIENCE 273(5271):63-67 Smith JR; PereiraSmith OM Replicative senescence: Implications for in vivo aging and tumor suppression | 25 | 280 |
| 37 | 0 | 25 | 37 1997 CANCER RESEARCH 57(19):4153-4157 Morelli C; Sherratt T; Trabanelli C; Rimessi P; Gualandi F; et al. Characterization of a 4-mb region at chromosome 6q21 harboring a replicative senescence gene | 3 | 15 |
| 38 | 3 | 31 | 38 1997 DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 21(6):471-478 Effros RB Loss of CD28 expression on T lymphocytes: A marker of replicative senescence | 5 | 42 |
| 39 | 4 | 79 | 39 1997 EUROPEAN JOURNAL OF CANCER 33(5):703-709 Campisi J The biology of replicative senescence | 16 | 170 |
| 40 | 0 | 0 | 40 1997 FASEB JOURNAL 11(9):A1262-A1262 Valenzuela HF; Effros RB T cell replicative senescence, CD28 and telomeres | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 2 | 77 | 41 1997 HEPATOLOGY 26(6):1434-1443 Factor VM; Jensen MR; Thorgeirsson SS Coexpression of c-myc and transforming growth factor alfa in the liver promotes early replicative senescence and diminishes regenerative capacity after partial hepatectomy in transgenic mice | 0 | 26 |
| 42 | 3 | 47 | 42 1997 IMMUNOLOGY TODAY 18(9):450-454 Effros RB; Pawelec G Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion? | 12 | 142 |
| 43 | 0 | 0 | 43 1997 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 38(4):4375-4375 Hjelmeland LM; Handa JT; Matsunaga H; AotakiKeen A; Sherwood SW; et al. Replicative senescence of human RPE cells in vitro | 0 | 0 |
| 44 | 0 | 0 | 44 1997 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 99(1):1022-1022 Effros RB; Spaulding CC Replicative senescence of T lymphocytes in aging and in AIDS. | 0 | 0 |
| 45 | 3 | 52 | 45 1997 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 45(4):482-488 Campisi J Aging and cancer: The double-edged sword of replicative senescence | 3 | 71 |
| 46 | 2 | 52 | 46 1997 ONCOGENE 15(5):495-503 Palmero I; McConnell B; Parry D; Brookes S; Hara E; et al. Accumulation of p(16INK4a) in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status | 2 | 57 |
| 47 | 3 | 81 | 47 1997 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 214(2):99-106 Chiu CP; Harley CB Replicative senescence and cell immortality: The role of telomeres and telomerase | 3 | 89 |
| 48 | 0 | 0 | 48 1998 AGING-CLINICAL AND EXPERIMENTAL RESEARCH 10(2):151-152 Cristofalo VJ; Tresini M Defects in signal transduction during replicative senescence of diploid human fibroblasts in vitro | 0 | 1 |
| 49 | 1 | 2 | 49 1998 AGING-CLINICAL AND EXPERIMENTAL RESEARCH 10(2):152-152 Effros RB Replicative senescence: Impact on T cell immunity in the elderly | 0 | 4 |
| 50 | 3 | 31 | 50 1998 AMERICAN JOURNAL OF HUMAN GENETICS 62(5):1003-1007 Effros RB Replicative senescence in the immune system: Impact of the hayflick limit on T-cell function in the elderly | 5 | 37 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 4 | 77 | 51 1998 BIOESSAYS 20(12):985-991 Faragher RGA; Kipling D How might replicative senescence contribute to human ageing? | 6 | 48 |
| 52 | 1 | 50 | 52 1998 CELL GROWTH & DIFFERENTIATION 9(1):85-95 Kang MK; Guo WT; Park NH Replicative senescence of normal human oral keratinocytes is associated with the loss of telomerase activity without shortening of telomeres | 3 | 40 |
| 53 | 0 | 0 | 53 1998 CIRCULATION 98(17):419-419 Kajstura J; Wang XW; Liu Y; Ahuja J; Leri A; et al. Myocyte regeneration is maintained in the old heart, challenging the concept of replicative senescence | 0 | 0 |
| 54 | 5 | 21 | 54 1998 CURRENT BIOLOGY 8(6):351-354 McConnell BB; Starborg M; Brookes S; Peters G Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts | 10 | 103 |
| 55 | 4 | 49 | 55 1998 EXPERIMENTAL CELL RESEARCH 240(1):66-74 Gonos ES; Derventzi A; Kveiborg M; Agiostratidou G; Kassem M; et al. Cloning and identification of genes that associate with mammalian replicative senescence | 3 | 46 |
| 56 | 0 | 0 | 56 1998 FASEB JOURNAL 12(5):A933-A933 Effros RB; Spaulding CC; Perillo NL; Baum LG Replicative senescence in T cells is associated with resistance to apoptosis. | 0 | 0 |
| 57 | 1 | 36 | 57 1998 FEBS LETTERS 427(2):203-208 Kato D; Miyazawa K; Ruas M; Starborg M; Wada I; et al. Features of replicative senescence induced by direct addition of antennapedia-p16(INK4A) fusion protein to human diploid fibroblasts | 3 | 39 |
| 58 | 0 | 0 | 58 1998 JOURNAL OF DENTAL RESEARCH 77:266-266 Kang MK; Park NH Telomerase, telomere and replicative senescence of normal human oral keratinocytes. | 0 | 0 |
| 59 | 0 | 0 | 59 1998 JOURNAL OF DENTAL RESEARCH 77:926-926 Kang MK; Park NH Telomerase, telomere and replicative senescence of normal human oral keratinocytes. | 0 | 0 |
| 60 | 0 | 0 | 60 1998 JOURNAL OF PATHOLOGY 184:45A-45A Parkinson EK Telomerase in replicative senescence and cancer | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 1 | 90 | 61 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(16):9078-9081 Sedivy JM Can ends justify the means? Telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells | 2 | 106 |
| 62 | 1 | 25 | 62 1998 TELOMERES AND TELOMERASE 211:177-189 Newbold RF Genetic control of telomerase and replicative senescence in human and rodent cells | 0 | 0 |
| 63 | 0 | 12 | 63 1998 TELOMERES AND TELOMERASE 211:189-197 Gasser SM; Newbold RF; Wynford-Thomas D; Shay JW; Kipling D; et al. Genetic control of telomerase and replicative senescence in human and rodent cells - Discussion | 0 | 0 |
| 64 | 4 | 22 | 64 1999 ADVANCES IN BLADDER RESEARCH 462:83-91 Puthenveettil JA; Burger MS; Reznikoff CA Replicative senescence in human uroepithelial cells | 0 | 10 |
| 65 | 2 | 40 | 65 1999 CURRENT BIOLOGY 9(17):939-945 Shelton DN; Chang E; Whittier PS; Choi D; Funk WD Microarray analysis of replicative senescence | 18 | 138 |
| 66 | 0 | 29 | 66 1999 CURRENT SCIENCE 76(4):470-473 Lavania UC; Lavania S; Vimala Y Telomere dynamism and developmental connection of differential telomerase activation in cell proliferation and replicative senescence | 0 | 2 |
| 67 | 2 | 33 | 67 1999 EXPERIMENTAL CELL RESEARCH 253(2):503-510 Morisaki H; Ando A; Nagata Y; Pereira-Smith O; Smith JR; et al. Complex mechanisms underlying impaired activation of Cdk4 and Cdk2 in replicative senescence: Roles of p16, p21, and cyclin D1 | 1 | 13 |
| 68 | 4 | 46 | 68 1999 EXPERIMENTAL GERONTOLOGY 34(5):633-644 Spaulding C; Guo W; Effros RB Resistance to apoptosis in human CD8+T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation | 7 | 60 |
| 69 | 0 | 0 | 69 1999 FASEB JOURNAL 13(7):A1328-A1328 Effros RB Immune consequences of T cell replicative senescence | 0 | 0 |
| 70 | 0 | 0 | 70 1999 FASEB JOURNAL 13(7):A1329-A1329 Sedivy JM Establishment and maintenance of replicative senescence in mammalian cells | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 0 | 23 | 71 1999 FEMS MICROBIOLOGY LETTERS 177(2):199-204 Barker MG; Brimage LJE; Smart KA Effect of Cu,Zn superoxide dismutase disruption mutation on replicative senescence in Saccharomyces cerevisiae | 0 | 32 |
| 72 | 0 | 50 | 72 1999 JOURNAL OF CELLULAR PHYSIOLOGY 179(1):11-17 Tresini M; Pignolo RJ; Allen RG; Cristofalo VJ Effects of donor age on the expression of a marker of replicative senescence (EPC-1) in human dermal fibroblasts | 0 | 9 |
| 73 | 2 | 35 | 73 1999 JOURNAL OF IMMUNOLOGY 162(8):4521-4526 Maini MK; Soares MVD; Zilch CF; Akbar AN; Beverley PCL Virus-induced CD8(+) T cell clonal expansion is associated with telomerase up-regulation and telomere length preservation: A mechanism for rescue from replicative senescence | 6 | 48 |
| 74 | 1 | 59 | 74 1999 JOURNAL OF IMMUNOLOGY 162(11):6572-6579 Vallejo AN; Brandes JC; Weyand CM; Goronzy JJ Modulation of CD28 expression: Distinct regulatory pathways during activation and replicative senescence | 3 | 45 |
| 75 | 0 | 0 | 75 1999 JOURNAL OF INVESTIGATIVE DERMATOLOGY 112(4):559-559 Chaturvedi V; Qin J; Denning M; Choubey D; Bacon P; et al. Differential expression and function of cell cycle regulatory proteins during keratinocyte (KC) proliferation, growth arrest, differentiation, replicative senescence (RS), and apoptosis | 0 | 0 |
| 76 | 0 | 41 | 76 1999 MOLECULAR VISION 5(38-40):U6-U12 Matsunaga H; Handa JT; Gelfman CM; Hjelmeland LM The mRNA phenotype of a human RPE cell line at replicative senescence | 0 | 0 |
| 77 | 1 | 65 | 77 1999 ONCOGENE 18(18):2789-2797 Fang L; Igarashi M; Leung J; Sugrue MM; Lee SW; et al. p21(Waf1/Cip1/Sdi1) induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53 | 4 | 56 |
| 78 | 0 | 0 | 78 1999 ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE 32(2):15-15 Toussaint O; Dumont P; Burton M; Frippiat C; Pascal T; et al. Long-term effects of sublethal oxidative stresses on the biomarkers of replicative senescence | 0 | 0 |
| 79 | 4 | 84 | 79 1999 ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE 32(2):69-75 Saretzki G; von Zglinicki T Replicative senescence as a model for aging: the role of oxidative stress and telomere shortening | 0 | 1 |
| 80 | 0 | 0 | 80 1999 ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE 32(2):225-225 Dierick JF; Dumont P; Eliaers F; Remacle J; Larsen PM; et al. Comparison between the protein expression in replicative senescence and in the long-term response to successive sublethal stresses of human diploid fibroblasts using proteome analysis | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 3 | 20 | 81 2000 ACTA BIOCHIMICA POLONICA 47(2):293-300 Jaruga E; Skierski J; Radziszewska E; Sikora E Proliferation and apoptosis of human T cells during replicative senescence - a critical approach | 0 | 3 |
| 82 | 2 | 47 | 82 2000 AIDS 14(7):771-780 Bestilny LJ; Gill MJ; Mody CH; Riabowol KT Accelerated replicative senescence of the peripheral immune system induced by HIV infection | 3 | 18 |
| 83 | 0 | 0 | 83 2000 AMERICAN JOURNAL OF HUMAN GENETICS 67(4):91-91 Kaur GP; Reddy DE; Athwal RS Cloning of a replicative senescence gene for immortal tumor cells. | 0 | 0 |
| 84 | 2 | 41 | 84 2000 APOPTOSIS 5(5):431-434 Plunkett FJ; Soares MVD; Salmon M; Akbar AN Regulation of apoptosis and replicative senescence in CD8+T cell following acute viral infection | 0 | 6 |
| 85 | 2 | 39 | 85 2000 ARCHIVES OF ORAL BIOLOGY 45(10):809-818 Lee G; Park BS; Han SE; Oh JE; You YO; et al. Concurrence of replicative senescence and elevated expression of p16(INK4A) with subculture-induced but not calcium-induced differentiation in normal human oral keratinocytes | 0 | 12 |
| 86 | 3 | 28 | 86 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 275(2):455-459 Kyrylenko S; Korhonen P; Kyrylenko O; Roschier M; Salminen A Expression of transcriptional repressor proteins mSin3A and 3B during aging and replicative senescence | 0 | 3 |
| 87 | 2 | 49 | 87 2000 BIOCHEMICAL SOCIETY TRANSACTIONS 28:226-233 Parkinson EK; Munro J; Steeghs K; Morrison V; Ireland H; et al. Replicative senescence as a barrier to human cancer | 1 | 14 |
| 88 | 2 | 38 | 88 2000 BIOCHEMICAL SOCIETY TRANSACTIONS 28:255-258 Soares MVD; Maini MK; Beverley PCL; Salmon M; Akbar AN Regulation of apoptosis and replicative senescence in CD8(+) T cells from patients with viral infections | 0 | 3 |
| 89 | 5 | 80 | 89 2000 CELL GROWTH & DIFFERENTIATION 11(7):373-384 Fuxe J; Akusjarvi G; Goike HM; Roos G; Collins VP; et al. Adenovirus-mediated overexpression of p15(INK4B) inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16(INK4A) | 2 | 24 |
| 90 | 3 | 52 | 90 2000 EXPERIMENTAL CELL RESEARCH 256(1):291-299 Martens UM; Chavez EA; Poon SSS; Schmoor C; Landsdorp PM Accumulation of short telomeres in human fibroblasts prior to replicative senescence | 7 | 60 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 1 | 45 | 91 2000 EXPERIMENTAL GERONTOLOGY 35(1):7-13 Ran QT; Pereira-Smith OM Genetic approaches to the study of replicative senescence | 1 | 11 |
| 92 | 0 | 9 | 92 2000 EXPERIMENTAL GERONTOLOGY 35(6-7):729-732 Wagner M; Jansen-Durr P Replicative senescence of human primary cells - molecules and mechanisms | 0 | 1 |
| 93 | 0 | 10 | 93 2000 EXPERIMENTAL GERONTOLOGY 35(9-10):1151-1155 Jansen-Durr P Viral oncogenes as tools to study replicative senescence of human cells | 1 | 1 |
| 94 | 0 | 0 | 94 2000 FASEB JOURNAL 14(8):A1458-A1458 Zhang ZY; Liu PH; Duan JM; Tong TJ Involvement of p16(INK4A) in replicative senescence of human diploid fibroblast which senescence delay can be induced by anti-sense p16(INK4A) expression. | 0 | 0 |
| 95 | 0 | 0 | 95 2000 FASEB JOURNAL 14(8):A1544-A1544 Tong TJ; Chen PL; Ding Y; Zhang ZY Instability of p16(INK4A)-related microsatellites in replicative senescence of human diploid fibroblast. | 0 | 0 |
| 96 | 0 | 32 | 96 2000 FEBS LETTERS 468(1):43-47 Pfeuty A; Gueride M Peroxide accumulation without major mitochondrial alteration in replicative senescence | 1 | 7 |
| 97 | 6 | 61 | 97 2000 FREE RADICAL BIOLOGY AND MEDICINE 28(3):361-373 Dumont P; Burton M; Chen QM; Gonos ES; Frippiat C; et al. Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast | 8 | 71 |
| 98 | 1 | 31 | 98 2000 GENE 252(1-2):217-225 Morelli C; Magnanini C; Mungall AJ; Negrini M; Barbanti-Brodano G Cloning and characterization of two overlapping genes in a subregion at 6q21 involved in replicative senescence and schizophrenia | 1 | 9 |
| 99 | 1 | 17 | 99 2000 GENERATIONS-JOURNAL OF THE AMERICAN SOCIETY ON AGING 24(1):43-47 Pereira-Smith OM; Bertram MJ Replicative senescence | 1 | 2 |
| 100 | 0 | 0 | 100 2000 HEPATOLOGY 32(4):475A-475A Paradis V; Dargere D; Youssef N; Bonvoust F; Bedossa P Chronic hepatitis C is a model of accelerated replicative senescence. Implication for the detection of hepatocellular carcinomas. | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 101 | 0 | 0 | 101 2000 JOURNAL OF DENTAL RESEARCH 79(5):1267-1267 You YO; Lee G; Min BM Effects of retinoic acid on proliferation and replicative senescence of normal human oral keratinocytes. | 0 | 0 |
| 102 | 2 | 47 | 102 2000 JOURNAL OF SURGICAL RESEARCH 92(1):85-95 Liao SX; Curci JA; Kelley BJ; Sicard GA; Thompson RW Accelerated replicative senescence of medial smooth muscle cells derived from abdominal aortic aneurysms compared to the adjacent inferior mesenteric artery | 0 | 9 |
| 103 | 3 | 76 | 103 2000 MECHANISMS OF AGEING AND DEVELOPMENT 118(1-2):23-34 Lansdorp PM Repair of telomeric DNA prior to replicative senescence | 0 | 24 |
| 104 | 1 | 18 | 104 2000 MECHANISMS OF AGEING AND DEVELOPMENT 121(1-3):181-185 Pawelec G Hypothesis: loss of telomerase inducibility and subsequent replicative senescence in cultured human T cells is a result of altered costimulation | 0 | 4 |
| 105 | 1 | 59 | 105 2000 MOLECULAR AND CELLULAR BIOLOGY 20(8):2803-2808 Webley K; Bond JA; Jones CJ; Blaydes JP; Craig A; et al. Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage | 5 | 56 |
| 106 | 1 | 47 | 106 2000 MOLECULAR AND CELLULAR GERONTOLOGY 908:99-110 Von Zglinicki T Role of oxidative stress in telomere length regulation and replicative senescence | 2 | 51 |
| 107 | 12 | 124 | 107 2000 MOLECULAR AND CELLULAR GERONTOLOGY 908:111-125 Chen QM Replicative senescence and oxidant-induced premature senescence - Beyond the control of cell cycle checkpoints | 1 | 27 |
| 108 | 0 | 2 | 108 2000 MOLECULAR AND CELLULAR GERONTOLOGY 908:310-314 Jaruga E; Skierski J; Radzieszewska E; Sikora E Replicative senescence of interleukin-2-dependent human T lymphocytes - Flow cytometric characteristics of phenotype changes | 0 | 1 |
| 109 | 6 | 63 | 109 2000 PATHOLOGIE BIOLOGIE 48(3):301-307 Wynford-Thomas D Replicative senescence: mechanisms and implications for human cancer | 0 | 4 |
| 110 | 0 | 62 | 110 2001 AMERICAN JOURNAL OF PATHOLOGY 158(4):1379-1390 Lunz JG; Contrucci S; Ruppert K; Murase N; Fung JJ; et al. Replicative senescence of biliary epithelial cells precedes bile duct loss in chronic liver allograft rejection - Increased expression of p21(WAF1/Cip1) as a disease marker and the influence of immunosuppressive drugs | 2 | 10 |
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| 111 | 2 | 37 | 111 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 282(2):493-498 Honda S; Weigel A; Hjelmeland LM; Handa JT Induction of telomere shortening and replicative senescence by cryopreservation | 0 | 8 |
| 112 | 1 | 24 | 112 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 282(4):934-939 Park WY; Hwang CI; Kang MJ; Seo JY; Chung JH; et al. Gene profile of replicative senescence is different from progeria or elderly donor | 0 | 11 |
| 113 | 4 | 43 | 113 2001 CANCER LETTERS 168(2):111-116 von Zglinicki T Telomeres and replicative senescence: is it only length that counts? | 3 | 15 |
| 114 | 0 | 0 | 114 2001 CLINICAL CANCER RESEARCH 7(11):3812S-3812S Shilkaitis A; Aldaz C; Steele VE; Lubet R; Grubbs C; et al. Terminal replicative senescence, a potential target for breast cancer chemoprevention strategies. | 0 | 0 |
| 115 | 0 | 38 | 115 2001 EXPERIMENTAL GERONTOLOGY 36(1):65-78 Lorenzini A; Hrelia S; Bordoni A; Biagi P; Frisoni L; et al. Is increased arachidonic acid release a cause or a consequence of replicative senescence? | 2 | 2 |
| 116 | 1 | 21 | 116 2001 EXPERIMENTAL GERONTOLOGY 36(1):79-88 Wein LM; Wu JT Estimation of replicative senescence via a population dynamics model of cells in culture | 0 | 2 |
| 117 | 3 | 56 | 117 2001 EXPERIMENTAL GERONTOLOGY 36(8):1327-1347 Wagner M; Hampel B; Bernhard D; Hala M; Zwerschke W; et al. Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis | 5 | 20 |
| 118 | 1 | 1 | 118 2001 EXPERIMENTAL GERONTOLOGY 37(1):181-181 Wagner M; Hampel B; Bernhard D; Hala M; Zwerschke W; et al. Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis (vol 36, pg 1327, 2001) | 0 | 0 |
| 119 | 1 | 39 | 119 2001 FASEB JOURNAL 15(6):1014-1020 Choi DH; Whittier PS; Oshima J; Funk WD Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains | 0 | 25 |
| 120 | 3 | 45 | 120 2001 FEBS LETTERS 499(1-2):101-106 Wagner M; Brosch G; Zwerschke W; Seto E; Loidl P; et al. Histone deacetylases in replicative senescence: evidence for a senescence-specific form of HDAC-2 | 0 | 8 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 0 | 0 | 121 2001 HEPATOLOGY 34(4):359A-359A Schnabl B; Graw A; Choi YH; Hagedorn C; Brenner DA Replicative senescence of activated human hepatic stellate cells is accompanied by an inflammatory and matrix degrading phenotype. | 0 | 0 |
| 122 | 3 | 33 | 122 2001 HUMAN PATHOLOGY 32(3):327-332 Paradis V; Youssef N; Dargere D; Ba N; Bonvoust F; et al. Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas | 3 | 41 |
| 123 | 2 | 62 | 123 2001 JOURNAL OF BONE AND MINERAL RESEARCH 16(8):1453-1464 Yudoh K; Matsuno H; Nakazawa F; Katayama R; Kimura T Reconstituting telomerase activity using the telomerase catalytic subunit prevents the telomere shorting and replicative senescence in human osteoblasts | 1 | 25 |
| 124 | 0 | 0 | 124 2001 JOURNAL OF DENTAL RESEARCH 80(4):1358-1358 You YO; Lee G; Min BM Molecular mechanisms of replicative senescence and its prevention by retinoic acid in normal human oral keratinocytes | 0 | 0 |
| 125 | 0 | 0 | 125 2001 JOURNAL OF INVESTIGATIVE DERMATOLOGY 117(2):521-521 Li G; Eller M; Gilchrest B Induction of replicative senescence markers by telomere 3 ' overhang specific DNA | 0 | 0 |
| 126 | 1 | 26 | 126 2001 JOURNAL OF THEORETICAL BIOLOGY 213(4):573-586 Sozou PD; Kirkwood TBL A stochastic model of cell replicative senescence based on telomere shortening, oxidative stress, and somatic mutations in nuclear and mitochondrial DNA | 3 | 18 |
| 127 | 6 | 97 | 127 2001 MATURITAS 38(1):25-37 Kipling D Telomeres, replicative senescence and human ageing | 2 | 11 |
| 128 | 0 | 0 | 128 2001 MATURITAS 38(1):37-38 Gompel; Kipling; Ropers; Naftolin; De Kloet Telomeres, replicative senescence and human ageing - Discussion | 0 | 0 |
| 129 | 3 | 39 | 129 2001 MOLECULAR AND CELLULAR BIOLOGY 21(17):5889-5898 Wang WG; Yang XL; Cristofalo VJ; Holbrook NJ; Gorospe M Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence | 1 | 19 |
| 130 | 4 | 49 | 130 2001 ONCOGENE 20(27):3541-3552 Munro J; Steeghs K; Morrison V; Ireland H; Parkinson EK Human fibroblast replicative senescence can occur in the absence of extensive cell division and short telomeres | 0 | 19 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 131 | 2 | 58 | 131 2001 ONCOGENE 20(41):5818-5825 Jung MS; Yun J; Chae HD; Kim JM; Kim SC; et al. p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor | 2 | 19 |
| 132 | 1 | 96 | 132 2001 ONCOGENE 20(49):7250-7256 Pearson M; Pelicci PG PML interaction with p53 and its role in apoptosis and replicative senescence | 1 | 36 |
| 133 | 4 | 67 | 133 2001 PATHOLOGIE BIOLOGIE 49(10):830-839 Gerland LM; Ffrench M; Magaud JP Cyclin dependent kinase inhibitors and replicative senescence. | 1 | 2 |
| 134 | 1 | 26 | 134 2001 SCIENCE 291(5505):868-871 Tang DG; Tokumoto YM; Apperly JA; Lloyd AC; Raff MC Lack of replicative senescence in cultured rat - Oligodendrocyte precursor cells | 3 | 91 |
| 135 | 2 | 14 | 135 2001 SCIENCE 291(5505):872-875 Mathon NF; Malcolm DS; Harrisingh MC; Cheng LL; Lloyd AC Lack of replicative senescence in normal rodent glia | 4 | 67 |
| 136 | 2 | 40 | 136 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 296(1):93-101 Blazer S; Khankin E; Segev Y; Ofir R; Yalon-Hacohen M; et al. High glucose-induced replicative senescence: point of no return and effect of telomerase | 0 | 4 |
| 137 | 2 | 30 | 137 2002 BIOCHEMICAL PHARMACOLOGY 64(5-6):1011-1017 Dierick JF; Eliaers F; Remacle J; Raes M; Fey SJ; et al. Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence | 2 | 6 |
| 138 | 4 | 117 | 138 2002 BIOGERONTOLOGY 3(4):195-206 Bree RT; Stenson-Cox C; Grealy M; Byrnes L; Gorman AM; et al. Cellular longevity: role of apoptosis and replicative senescence | 0 | 8 |
| 139 | 0 | 41 | 139 2002 BIOGERONTOLOGY 3(4):213-222 Rubelj I; Huzak M; Brdar B; Pereira-Smith OM A single-stage mechanism controls replicative senescence through Sudden Senescence Syndrome | 0 | 0 |
| 140 | 3 | 30 | 140 2002 BIOGERONTOLOGY 3(6):365-372 Matuoka K; Chen KY Telomerase positive human diploid fibroblasts are resistant to replicative senescence but not premature senescence induced by chemical reagents | 0 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 141 | 1 | 25 | 141 2002 CHINESE MEDICAL JOURNAL 115(6):803-809 Yang J; Tang FQ; Gu HH; Deng XY; Weng XX; et al. Epstein-Barr virus induces human nasopharyngeal epithelial cells to escape from the replicative senescence | 0 | 1 |
| 142 | 0 | 0 | 142 2002 CLINICAL IMMUNOLOGY 103(3):S92-S93 Dagarag M; Effros R Replicative senescence of CD8+T cells in HIV disease. | 0 | 0 |
| 143 | 2 | 43 | 143 2002 EXPERIMENTAL GERONTOLOGY 37(2-3):191-196 Effros RB; Globerson A Hematopoietic cells and replicative senescence | 0 | 10 |
| 144 | 2 | 42 | 144 2002 EXPERIMENTAL GERONTOLOGY 37(8-9):1113-1120 Statuto M; Bianchi C; Perego R; Del Monte U Drop of connexin 43 in replicative senescence of human fibroblasts HEL-299 as a possible biomarker of senescence | 0 | 3 |
| 145 | 0 | 32 | 145 2002 EXPERIMENTAL GERONTOLOGY 37(10-11):1165-1174 Hutter E; Unterluggauer H; Uberall F; Schramek H; Jansen-Durr P Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress | 0 | 2 |
| 146 | 5 | 39 | 146 2002 FEBS LETTERS 531(3):499-504 Dierick JF; Kalume DE; Wenders F; Salmon M; Dieu M; et al. Identification of 30 protein species involved in replicative senescence and stress-induced premature senescence | 2 | 9 |
| 147 | 0 | 0 | 147 2002 HEPATOLOGY 36(4):254A-254A Koteish A; Yang SQ; Huang JW; Lin HZ; Villanueva JA; et al. Oxidant induced replicative senescence: Mechanism for ethanol-related mitoinhibition?. | 0 | 0 |
| 148 | 0 | 0 | 148 2002 HEPATOLOGY 36(4):560A-560A Trak-Smayra V; Paradis V; Contreras J; Dubois S; Marcellin P; et al. Replicative senescence and allograft fibrosis following liver transplantation (OLT) for hepatitis C virus (HCV)-related liver disease. | 0 | 0 |
| 149 | 3 | 30 | 149 2002 IN VIVO 16(6):393-396 Warner HR Recent progress in understanding the relationships among aging, replicative senescence, cell turnover and cancer | 0 | 2 |
| 150 | 3 | 38 | 150 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(10):7857-7864 Mawal-Dewan M; Lorenzini A; Frisoni L; Zhang H; Cristofalo VJ; et al. Regulation of collagenase expression during replicative senescence in human fibroblasts by Akt-forkhead signaling | 1 | 6 |
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| 151 | 3 | 61 | 151 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(32):28609-28617 Rubio MA; Kim SH; Campisi J Reversible manipulation of telomerase expression and telomere length - Implications for the ionizing radiation response and replicative senescence of human cells | 0 | 15 |
| 152 | 0 | 0 | 152 2002 JOURNAL OF DENTAL RESEARCH 81:A407-A407 You YO; Lee G; Min BM Retinoic acid controls replicative senescence and apoptosis of normal human oral keratinocytes. | 0 | 0 |
| 153 | 0 | 0 | 153 2002 JOURNAL OF INVESTIGATIVE DERMATOLOGY 119(1):209-209 Tang J; Gordon GM; Nickoloff BJ; Foreman KE The helix-loop-helix protein Id-1 delays onset of replicative senescence in human endothelial cells | 0 | 0 |
| 154 | 10 | 180 | 154 2002 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 57(7):B257-B269 Marcotte R; Wang E Replicative senescence revisited | 0 | 7 |
| 155 | 1 | 37 | 155 2002 LABORATORY INVESTIGATION 82(8):1073-1079 Tang J; Gordon GM; Nickoloff BJ; Foreman KE The helix-loop-helix protein Id-1 delays onset of replicative senescence in human endothelial cells | 1 | 13 |
| 156 | 0 | 0 | 156 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(4):445-445 Sell C; Cristofalo VJ Cell aging in vitro: what we can learn about mammalian aging from replicative senescence | 0 | 0 |
| 157 | 6 | 83 | 157 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(12):1681-1694 Hwang ES Replicative senescence and senescence-like state induced in cancer-derived cells | 0 | 6 |
| 158 | 1 | 68 | 158 2002 MOLECULAR & CELLULAR PROTEOMICS 1(4):280-292 Benvenuti S; Cramer R; Quinn CC; Bruce J; Zvelebil M; et al. Differential proteome analysis of replicative senescence in rat embryo fibroblasts | 2 | 13 |
| 159 | 1 | 33 | 159 2002 ONCOGENE 21(7):981-989 Djelloul S; Tarunina M; Barnouin K; Mackay A; Jat PS Differential protein expression, DNA binding and interaction with SV40 large tumour antigen implicate the p63-family of proteins in replicative senescence | 1 | 8 |
| 160 | 1 | 52 | 160 2002 ONCOGENE 21(21):3270-3273 Allsopp RC; Weissman IL Replicative senescence of hematopoietic stem cells during serial transplantation: does telomere shortening play a role? | 0 | 15 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 161 | 3 | 38 | 161 2002 ONCOGENE 21(28):4403-4413 Benvenuti S; Cramer R; Bruce J; Waterfield MD; Jat PS Identification of novel candidates for replicative senescence by functional proteomics | 2 | 9 |
| 162 | 2 | 66 | 162 2002 ONCOGENE 21(47):7266-7276 Morelli C; Karayianni E; Magnanini C; Mungall AJ; Thorland E; et al. Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors | 0 | 12 |
| 163 | 1 | 1 | 163 2002 ONCOGENE 21(49):7609-7609 Benvenuti S; Cramer R; Bruce J; Waterfield MD; Jat PS Identification of novel candidates for replicative senescence by functional proteomics (vol 21, pg 4403, 2002) | 0 | 0 |
| 164 | 3 | 67 | 164 2002 TRANSPLANT IMMUNOLOGY 9(2-4):165-171 Chkhotua A; Shohat M; Tobar A; Magal N; Kaganovski E; et al. Replicative senescence in organ transplantation - mechanisms and significance | 0 | 2 |
| 165 | 3 | 69 | 165 2003 BLOOD 101(7):2711-2720 Brenchley JM; Karandikar NJ; Betts MR; Ambrozak DR; Hill BJ; et al. Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8(+) T cells | 2 | 40 |
| 166 | 0 | 0 | 166 2003 BLOOD 102(11):221A-221A Sun LQ; Lee DW; Xiao WH; Raabe E; Zhang Q; et al. Replicative senescence and premature aging in mice with disruption of PASG (proliferation associated SNF2-like gene). | 0 | 0 |
| 167 | 0 | 0 | 167 2003 CANCER GENE THERAPY 10:S7-S7 Krones-Herzig A; Adamson ED; Mercola DA Identification of EGR-1 as a novel upstream "gatekeeper" of the p53 tumor suppressor in replicative senescence | 0 | 0 |
| 168 | 0 | 31 | 168 2003 CELL STRUCTURE AND FUNCTION 28(6):495-503 Kamino H; Hiratsuka M; Toda T; Nishigaki R; Osaki M; et al. Searching for genes involved in arteriosclerosis: Proteomic analysis of cultured human umbilical vein endothelial cells undergoing replicative senescence | 0 | 0 |
| 169 | 0 | 19 | 169 2003 CHINESE SCIENCE BULLETIN 48(7):680-686 Ji RR; Zhang J; Wang SW; Liao XD; Chen LY D-galactose induces replicative senescence of rat pulmonary microvascular endothelial cells | 0 | 0 |
| 170 | 7 | 156 | 170 2003 CURRENT HIV RESEARCH 1(2):153-165 Effros RB Replicative senescence: The final stage of memory T cell differentiation? | 1 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 171 | 1 | 26 | 171 2003 EMBO REPORTS 4(11):1061-1066 Wei WY; Herbig U; Wei S; Dutriaux A; Sedivy JM Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts | 1 | 6 |
| 172 | 7 | 74 | 172 2003 EXPERIMENTAL CELL RESEARCH 283(1):22-35 Stephens P; Cook H; Hilton J; Jones CJ; Haughton MF; et al. An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype | 0 | 4 |
| 173 | 0 | 0 | 173 2003 EXPERIMENTAL GERONTOLOGY 38(1-2):219-219 Loscher M; Grillari J; Katinger H Screening for proteins interacting with SNEV, a protein involved in replicative senescence, using the yeast two-hybrid system | 0 | 0 |
| 174 | 4 | 67 | 174 2003 EXPERIMENTAL GERONTOLOGY 38(11-12):1251-1257 Foreman KE; Tang J Molecular mechanisms of replicative senescence in endothelial cells | 0 | 0 |
| 175 | 10 | 83 | 175 2003 EXPERIMENTAL GERONTOLOGY 38(11-12):1259-1264 Von Zglinicki T Replicative senescence and the art of counting | 2 | 8 |
| 176 | 0 | 0 | 176 2003 FREE RADICAL BIOLOGY AND MEDICINE 35:S108-S109 Petropoulos I; Picot C; Perichon M; Cintrat JC; Friguet B MsrA and MsrB are down-regulated during replicative senescence of WI 38 fibroblasts | 0 | 0 |
| 177 | 0 | 0 | 177 2003 GERONTOLOGIST 43:9-9 Ghandhi S Gene expression in replicative senescence in HDF | 0 | 0 |
| 178 | 0 | 0 | 178 2003 GERONTOLOGIST 43:10-10 Effros R; Dagarag M Genetic manipulation of replicative senescence in virus-specific T cells | 1 | 1 |
| 179 | 1 | 52 | 179 2003 HEPATOLOGY 37(3):653-664 Schnabl B; Purbeck CA; Choi YH; Hagedorn CH; Brenner DA Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype | 0 | 7 |
| 180 | 0 | 51 | 180 2003 HUMAN GENE THERAPY 14(12):1169-1179 Cooper RN; Thiesson D; Furling D; Di Santo JP; Butler-Browne GS; et al. Extended amplification in vitro and replicative senescence: Key factors implicated in the success of human myoblast transplantation | 0 | 3 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 181 | 2 | 22 | 181 2003 HUMAN PATHOLOGY 34(9):924-928 Ferlicot S; Durrbach A; Ba N; Desvaux D; Bedossa P; et al. The role of replicative senescence in chronic allograft nephropathy | 1 | 2 |
| 182 | 0 | 54 | 182 2003 JOURNAL OF CELLULAR BIOCHEMISTRY 89(3):576-588 Marcotte R; Qian JF; Chen J; Wang E nMad4, c-Myc endogenous inhibitor, induces a replicative senescence-like state when overexpressed in human fibroblasts | 0 | 1 |
| 183 | 1 | 23 | 183 2003 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 58(9):776-779 Cristofalo VJ; Beck J; Allen RG Commentary - Cell senescence: An evaluation of replicative senescence in culture as a model for cell aging in situ | 1 | 2 |
| 184 | 2 | 28 | 184 2003 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 58(9):779-781 Smith JR Cell senescence: an evaluation of replicative senescence in culture as a model for aging in situ - Author's response to commentary | 0 | 0 |
| 185 | 3 | 31 | 185 2003 KIDNEY INTERNATIONAL 63(6):2144-2151 Vogt S; Iking-Konert C; Hug F; Andrassy K; Hansch GM Shortening of telomeres: Evidence for replicative senescence of T cells derived from patients with Wegener's granulomatosis | 0 | 3 |
| 186 | 0 | 15 | 186 2003 MECHANISMS OF AGEING AND DEVELOPMENT 124(8-9):853-855 Hornsby PJ Replicative senescence of human and mouse cells in culture: significance for aging research | 0 | 1 |
| 187 | 0 | 27 | 187 2003 MECHANISMS OF AGEING AND DEVELOPMENT 124(10-12):1025-1034 Wang PC; Zhang ZY; Ma XF; Yu H; Liu XW; et al. HDTIC-1 and HDTIC-2, two compounds extracted from Astragali Radix, delay replicative senescence of human diploid fibroblasts | 0 | 1 |
| 188 | 1 | 10 | 188 2003 NATURE BIOTECHNOLOGY 21(3):229-230 von Zglinicki T; Petrie J; Kirkwood TBL Telomere-driven replicative senescence is a stress response | 1 | 5 |
| 189 | 0 | 28 | 189 2003 NATURE GENETICS 33(4):492-496 Stewart SA; Ben-Porath I; Carey VJ; O'Connor BF; Hahn WC; et al. Erosion of the telomeric single-strand overhang at replicative senescence | 6 | 60 |
| 190 | 2 | 52 | 190 2003 ONCOGENE 22(3):433-444 Ramirez RD; Herbert BS; Vaughan MB; Zou Y; Gandia K; et al. Bypass of telomere-dependent replicative senescence (M1) upon overexpression of Cdk4 in normal human epithelial cells | 2 | 15 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 191 | 0 | 45 | 191 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(6):3233-3238 Krones-Herzig A; Adamson E; Mercola D Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence | 0 | 11 |
| 192 | 2 | 49 | 192 2004 AGING CELL 3(5):309-317 Zmijewski JW; Jope RS Nuclear accumulation of glycogen synthase kinase-3 during replicative senescence of human fibroblasts | 0 | 0 |
| 193 | 9 | 94 | 193 2004 CANCER IMMUNOLOGY IMMUNOTHERAPY 53(10):925-933 Effros RB Replicative senescence of CD8 T cells: potential effects on cancer immune surveillance and immunotherapy | 0 | 1 |
| 194 | 0 | 57 | 194 2004 CIRCULATION RESEARCH 94(6):768-775 Haendeler J; Hoffmann J; Diehl JF; Vasa M; Spyridopoulos I; et al. Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells | 0 | 8 |
| 195 | 7 | 106 | 195 2004 CYTOGENETIC AND GENOME RESEARCH 105(2-4):455-463 Smith SK; Kipling D The role of replicative senescence in cancer and human ageing: utility (or otherwise) of murine models | 0 | 0 |
| 196 | 2 | 48 | 196 2004 EMBO JOURNAL 23(13):2554-2563 Gire W; Roux P; Wynford-Thomas D; Brondello JM; Dulic V DNA damage checkpoint kinase Chk2 triggers replicative senescence | 0 | 0 |
| 197 | 0 | 48 | 197 2004 EUROPEAN JOURNAL OF CELL BIOLOGY 83(11):691-700 Pellegrini G; Dellambra E; Paterna P; Golisano O; Traverso CE; et al. Telomerase activity is sufficient to bypass replicative senescence in human limbal and conjunctival but not corneal keratinocytes | 0 | 0 |
| 198 | 6 | 64 | 198 2004 EXPERIMENTAL CELL RESEARCH 298(2):549-559 Brooke S; Rowe J; del Arroyo AG; Bond J; Peters G Contribution of p16(INK4a) to replicative senescence of human fibroblasts | 0 | 2 |
| 199 | 6 | 85 | 199 2004 EXPERIMENTAL GERONTOLOGY 39(4):517-524 Effros RB Replicative senescence of CD8 T cells: effect on human ageing | 0 | 0 |
| 200 | 6 | 55 | 200 2004 EXPERIMENTAL GERONTOLOGY 39(6):885-890 Effros RB From Hayflick to Walford: the role of T cell replicative senescence in human aging | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 201 | 4 | 50 | 201 2004 EXPERIMENTAL GERONTOLOGY 39(9):1369-1378 Yoon IK; Kim HK; Kim YK; Song IH; Kim W; et al. Exploration of replicative senescence-associated genes in human dermal fibroblasts by cDNA microarray technology | 0 | 0 |
| 202 | 3 | 37 | 202 2004 FEBS LETTERS 558(1-3):74-78 Picot CR; Perichon M; Cintrat JC; Friguet B; Petropoulos I The peptide methionine sulfoxide reductases, MsrA and MsrB (hCBS-1), are downregulated during replicative senescence of human WI-38 fibroblasts | 1 | 5 |
| 203 | 2 | 52 | 203 2004 FEBS LETTERS 567(2-3):281-286 Wang X; Bregegere F; Soroka Y; Frusic-Zlotkin M; Milner Y Replicative senescence enhances apoptosis induced by pemphigus autoimmune antibodies in human keratinocytes | 0 | 0 |
| 204 | 1 | 48 | 204 2004 HEPATOLOGY 39(2):403-411 Yang SQ; Koteish A; Lin HZ; Huang JW; Roskams T; et al. Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease | 0 | 3 |
| 205 | 0 | 84 | 205 2004 JOURNAL OF THEORETICAL BIOLOGY 227(2):253-264 Karpinets TV; Foy BD Model of the developing tumorigenic phenotype in mammalian cells and the roles of sustained stress and replicative senescence | 0 | 0 |
| 206 | 1 | 56 | 206 2004 JOURNAL OF THEORETICAL BIOLOGY 230(3):333-341 Poyatos JF; Carnero A Non-neutral role of replicative senescence in tissue homeostasis and tumorigenesis | 0 | 0 |
| 207 | 1 | 38 | 207 2004 MECHANISMS OF AGEING AND DEVELOPMENT 125(5):359-366 Han JH; Roh MS; Park CH; Park KC; Cho KH; et al. Selective COX-2 inhibitor, NS-398, inhibits the replicative senescence of cultured dermal fibroblasts | 0 | 1 |
| 208 | 15 | 338 | 208 2004 MECHANISMS OF AGEING AND DEVELOPMENT 125(10-11):827-848 Cristofalo VJ; Lorenzini A; Allen RG; Torres C; Tresini M Replicative senescence: a critical review | 0 | 0 |
| 209 | 2 | 45 | 209 2004 MOLECULAR BIOLOGY OF THE CELL 15(8):3709-3718 Zou Y; Sfeir A; Gryaznov SM; Shay JW; Wright WE Does a sentinel or a subset of short telomeres determine replicative senescence? | 1 | 4 |
| 210 | 2 | 40 | 210 2004 ONCOGENE 23(37):6193-6198 Zhang H; Herbert BS; Pan KH; Shay JW; Cohen SN Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 211 | 3 | 10 | 211 2004 STRATEGIES FOR ENGINEERED NEGLIGIBLE SENESCENCE: WHY GENUINE CONTROL OF AGING MAY BE FORESEEABLE 1019:123-126 Effros RB T cell replicative senescence - Pleiotropic effects on human aging | 0 | 0 |
| 212 | 4 | 26 | 212 2004 TRANSPLANTATION 77(11):1755-1760 Trak-Smayra V; Contreras J; Dondero F; Durand F; Dubois S; et al. Role of replicative senescence in the progression of fibrosis in hepatitis C virus (HCV) recurrence after liver transplantation | 0 | 0 |
| 213 | 1 | 48 | 213 2005 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1703(2):261-266 Petropoulos I; Friguet B Protein maintenance in aging and replicative senescence: a role for the peptide methionine sulfoxide reductases | 0 | 0 |
| 214 | 2 | 31 | 214 2005 EMBO REPORTS 6(2):158-164 Wang WG; Martindale JL; Yang XL; Chrest FJ; Gorospe M Increased stability of the p16 mRNA with replicative senescence | 0 | 0 |
| 215 | 6 | 82 | 215 2005 EXPERIMENTAL GERONTOLOGY 40(1-2):17-26 Davis T; Skinner JW; Faragher RGA; Jones CJ; Kipling D Replicative senescence in sheep fibroblasts is a p53 dependent process | 0 | 0 |
| 216 | 2 | 36 | 216 2005 WOUND REPAIR AND REGENERATION 13(1):76-83 Vande Berg JS; Rose MA; Haywood-Reid PL; Rudolph R; Payne WG; et al. Cultured pressure ulcer fibroblasts show replicative senescence with elevated production of plasmin, plasminogen activator inhibitor-1, and transforming growth factor-beta 1 | 0 | 0 |
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