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Author(s): Koeller KM; Wong CH
Title: Enzymes for chemical synthesis
Source: NATURE 409 (6817): 232-240
Date: 2001 JAN 11
Document Type: Journal : Review
DOI:
Language: English
Comment:
Address: Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA.
Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA. Reprint: Koeller, KM, Scripps Res Inst, Dept Chem, 10550 N Torrey Pines Rd, La
Jolla, CA 92037 USA. E-mail:
Abstract: New catalytic synthetic methods in organic chemistry that satisfy increasingly stringent environmental constraints are in great demand by the pharmaceutical and chemical industries. In addition, novel catalytic procedures are necessary to produce the emerging classes of organic compounds that are becoming the targets of molecular and biomedical research. Enzyme-catalysed chemical transformations are now widely recognized as practical alternatives to traditional (non-biological) organic synthesis, and as convenient solutions to certain intractable synthetic problems.
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