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Wed Jan 18 15:30:25 2006

Papers by J Massague

Nodes: 299, Authors: 586, Journals: 71, Outer References: 4749, Words: 887
Collection span: 1977 - 2005
View: Overview. Sorted by year, source, volume, issue, page. Page 3 of 3: [  1  2  3 ]

#LCRNCRNode / Date / Journal / AuthorLCSGCS
2011459201 1997 GENES & DEVELOPMENT 11 (23): 3157-3167
Liu F; Pouponnot C; Massague J
Dual role of the Smad4/DPC4 tumor suppressor in TGF beta-inducible transcriptional complexes
28263
202929202 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (27): 17160-17165
Arribas J; LopezCasillas F; Massague J
Role of the juxtamembrane domains of the transforming growth factor-alpha precursor and the beta-amyloid precursor protein in regulated ectodomain shedding
064
2031173203 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (41): 25863-25872
Blain SW; Montalvo E; Massague J
Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) with cyclin A-Cdk2 and cyclin D2-Cdk4
3148
20400204 1997 JOURNAL OF BONE AND MINERAL RESEARCH 12: 55-55
Selander KS; Chirgwin JM; Yin JJ; Dallas M; Grubbs BG; et al.
Constitutively active transforming growth factor-beta (TGF beta) type I receptor increases parathyroid hormone-related protein (PTHrP) production by breast cancer cells in vitro and bone metastasis in vivo.
01
205430205 1997 NATURE 387 (6631): 417-422
Iavarone A; Massague J
Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15
11208
206724206 1997 NATURE 388 (6637): 82-87
Hata A; Lo RS; Wotton D; Lagna G; Massague J
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4
21219
207530207 1997 NATURE 388 (6637): 87-93
Shi YG; Hata A; Lo RS; Massague J; Pavletich NP
A structural basis for mutational inactivation of the tumour suppressor Smad4
25235
208634208 1997 NATURE 389 (6651): 618-622
Kretzschmar M; Doody J; Massague J
Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1
19337
209746209 1997 TRENDS IN CELL BIOLOGY 7 (5): 187-192
Massague J; Hata A; Liu F
TGF-beta signalling through the Smad pathway
7205
21052295210 1998 ANNUAL REVIEW OF BIOCHEMISTRY 67: 753-791
Massague J
TGF-beta signal transduction
391616
#LCRNCRNode / Date / Journal / AuthorLCSGCS
211832211 1998 CANCER RESEARCH 58 (13): 2727-2732
Pasche B; Luo Y; Rao PH; Nimer SD; Dmitrovsky E; et al.
Type I transforming growth factor beta receptor maps to 9q22 and exhibits a polymorphism and a rare variant within a polyalanine tract
137
212741212 1998 CELL 94 (5): 585-594
Shi YG; Wang YF; Jayaraman L; Yang HJ; Massague J; et al.
Crystal structure of a Smad MH1 domain bound to DNA: Insights on DNA binding in TGF-beta signaling
18273
2131252213 1998 CURRENT OPINION IN GENETICS & DEVELOPMENT 8 (1): 103-111
Kretzschmar M; Massague J
SMADs: mediators and regulators of TGF-beta signaling
3244
2141342214 1998 EMBO JOURNAL 17 (4): 996-1005
Lo RS; Chen YG; Shi YG; Pavletich NP; Massague J
The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors
17113
21500215 1998 FASEB JOURNAL 12 (8): A1292-A1292
Hata A; Massague J
The TGF beta/SMAD signaling pathway
00
2161054216 1998 GENES & DEVELOPMENT 12 (2): 186-197
Hata A; Lagna G; Massague J; Hemmati-Brivanlou A
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
16268
2171949217 1998 GENES & DEVELOPMENT 12 (14): 2144-2152
Chen YG; Hata A; Lo RS; Wotton D; Shi YG; et al.
Determinants of specificity in TGF-beta signal transduction
17134
21800218 1998 HEPATOLOGY 28 (4): 437A-437A
Oberthur A; Jung D; Massague J; Schirmacher P; Dienes HP; et al.
Smad activation in myofibroblastic hepatic stellate cells by autocrine TGF beta stimulation
00
2191151219 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (36): 22865-22868
Pouponnot C; Jayaraman L; Massague J
Physical and functional interaction of SMADs and p300/CBP
9188
220654220 1998 JOURNAL OF THE NATIONAL CANCER INSTITUTE 90 (17): 1284-1291
Cordon-Cardo C; Koff A; Drobnjak M; Capodieci P; Osman I; et al.
Distinct altered patterns of p27(KIP1) gene expression in benign prostatic hyperplasia and prostatic carcinoma
0151
#LCRNCRNode / Date / Journal / AuthorLCSGCS
2211062221 1998 MECHANISMS OF DEVELOPMENT 75 (1-2): 95-105
Mahony D; Weis FMB; Massague J; Gurdon JB
XTrR-I is a TGF beta receptor and overexpression of a truncated form of the receptor inhibits axis formation and dorsalising activity
05
222946222 1998 MOLECULAR MEDICINE TODAY 4 (6): 257-262
Hata A; Shi YG; Massague J
TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads
086
223214223 1998 NATURE GENETICS 20 (4): 325-326
Liu F; Massague J; Altaba ARI
Carboxy-terminally truncated Gli3 proteins associate with Smads
146
22400224 1999 BLOOD 94 (10): 276A-276A
Jakubowiak A; Pouponnot C; Frank R; Massague J; Nimer SD
Interaction between TGF-beta 1 signaling pathway and AML1 proteins.
00
225731225 1999 CANCER RESEARCH 59 (22): 5678-5682
Pasche B; Kolachana P; Nafa K; Satagopan J; Chen YG; et al.
T beta R-I(6A) is a candidate tumor susceptibility allele
257
2261059226 1999 CELL 96 (3): 425-436
Huse M; Chen YG; Massague J; Kuriyan J
Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12
11132
2271573227 1999 CELL 97 (1): 29-39
Wotton D; Lo RS; Lee S; Massague J
A Smad transcriptional corepressor
19259
22825228 1999 EUROPEAN JOURNAL OF CANCER 35: S1-S1
Massague J
Cell cycle control by TGF-beta signals
00
22900229 1999 FASEB JOURNAL 13 (7): A1584-A1584
Massague J
TGF-beta/SMAD pathway: Specificity and interaction with ras and STAT pathways
00
2301878230 1999 GENES & DEVELOPMENT 13 (7): 804-816
Kretzschmar M; Doody J; Timokhina I; Massague J
A mechanism of repression of TGF beta/Smad signaling by oncogenic Ras
22292
#LCRNCRNode / Date / Journal / AuthorLCSGCS
2311541231 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274 (6): 3672-3677
Chen YG; Massague J
Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors
567
232852232 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274 (47): 33637-33643
Calonge MJ; Massague J
Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells
974
233342233 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274 (52): 37105-37110
Wotton D; Lo RS; Swaby LAC; Massague J
Multiple modes of repression by the Smad transcriptional corepressor TGIF
865
234544234 1999 JOURNAL OF CLINICAL INVESTIGATION 103 (2): 197-206
Yin JJ; Selander K; Chirgwin JM; Dallas M; Grubbs BG; et al.
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
10198
235547235 1999 MOLECULAR AND CELLULAR BIOLOGY 19 (1): 916-922
Iavarone A; Massague J
E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest
463
2361560236 1999 MOLECULAR AND CELLULAR BIOLOGY 19 (9): 5913-5922
Warner BJ; Blain SW; Seoane J; Massague J
Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway
8100
237730237 1999 NATURE 397 (6721): 710-713
Ulloa L; Doody J; Massague J
Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway
9308
238830238 1999 NATURE 401 (6752): 480-485
Onichtchouk D; Chen YG; Dosch R; Gawantka V; Dellus H; et al.
Silencing of TGF-beta signalling by the pseudoreceptor BAMBI
5137
23916239 1999 NATURE CELL BIOLOGY 1 (5): E117-E119
Massague J
Wounding smad
010
24026240 1999 NATURE CELL BIOLOGY 1 (8): 472-478
Lo RS; Massague J
Ubiquitin-dependent degradation of TGF-beta-activated Smad2
9139
#LCRNCRNode / Date / Journal / AuthorLCSGCS
241846241 2000 CELL 100 (2): 229-240
Hata A; Seoane J; Lagna G; Montalvo E; Hemmati-Brivanlou A; et al.
OAZ uses distinct DNA-and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways
15155
24223148242 2000 CELL 103 (2): 295-309
Massague J; Blain SW; Lo RS
TGF beta signaling in growth control, cancer, and heritable disorders
20572
2432190243 2000 EMBO JOURNAL 19 (8): 1745-1754
Massague J; Wotton D
Transcriptional control by the TGF-beta/Smad signaling system
17654
24423171244 2000 GENES & DEVELOPMENT 14 (6): 627-644
Massague J; Chen YG
Controlling TGF-beta signaling
10616
2451249245 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275 (36): 27973-27978
Gouedard L; Chen YG; Thevenet L; Racine C; Borie S; et al.
Engagement of bone morphogenetic protein type IB receptor and Smad1 signaling by anti-Mullerian hormone and its type II receptor
156
246832246 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275 (41): 32066-32070
Blain SW; Massague J
Different sensitivity of the transforming growth factor-ss cell cycle arrest pathway to c-Myc and IMDM-2
012
247848247 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275 (51): 40282-40287
Jakubowiak A; Pouponnot C; Berguido F; Frank R; Mao SF; et al.
Inhibition of the transforming growth factor beta 1 signaling pathway by the AML1/ETO leukemia-associated fusion protein
239
2481133248 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275 (52): 40710-40717
Jayaraman L; Massague J
Distinct oligomeric states of SMAD proteins in the transforming growth factor-beta pathway
645
249637249 2000 MOLECULAR AND CELLULAR BIOLOGY 20 (17): 6201-6211
Dou CL; Lee J; Liu B; Liu F; Massague J; et al.
BF-1 interferes with transforming growth factor beta signaling by associating with Smad partners
224
250820250 2000 NATURE CELL BIOLOGY 2 (8): 559-562
Xu L; Chen YG; Massague J
The nuclear import function of Smad2 is masked by SARA and unmasked by TGF beta-dependent phosphorylation
854
#LCRNCRNode / Date / Journal / AuthorLCSGCS
251424251 2000 NATURE GENETICS 25 (2): 205-208
Gripp KW; Wotton D; Edwards MC; Roessler E; Ades L; et al.
Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination
693
25227109252 2000 NATURE REVIEWS MOLECULAR CELL BIOLOGY 1 (3): 169-178
Massague J
How cells read TGF-beta signals
3415
253819253 2000 SCIENCE 287 (5450): 92-97
Wu G; Chen YG; Ozdamar B; Gyuricza CA; Chong PA; et al.
Structural basis of Smad2 recognition by the Smad anchor for receptor activation
1086
25400254 2001 BLOOD 98 (11): 607A-608A
Bollard CM; Rossig C; Calonge J; Huls H; Massague J; et al.
Adapting a TGF-beta-related tumor protection strategy to enhance anti-tumor immunity.
00
255742255 2001 CANCER RESEARCH 61 (1): 256-260
Fink SP; Swinler SE; Lutterbaugh JD; Massague J; Thiagalingam S; et al.
Transforming growth factor-beta-induced growth inhibition in a smad4 mutant colon adenoma cell line
039
256764256 2001 CELL GROWTH & DIFFERENTIATION 12 (9): 457-463
Wotton D; Knoepfler PS; Laherty CD; Eisenman RN; Massague J
The Smad transcriptional corepressor TGIF recruits mSin3
124
2571652257 2001 EMBO JOURNAL 20 (1-2): 128-136
Lo RS; Wotton D; Massague J
Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF
160
2581136258 2001 MOLECULAR CELL 8 (3): 671-682
Huse M; Muir TW; Xu L; Chen YG; Kuriyan J; et al.
The TGF beta receptor activation process: An inhibitor-to substrate-binding switch
577
2591449259 2001 MOLECULAR CELL 8 (6): 1277-1289
Wu JW; Hu M; Chai JJ; Seoane J; Huse M; et al.
Crystal structure of a phosphorylated Smad2: Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling
666
260247260 2001 NATURE CELL BIOLOGY 3 (4): 392-399
Staller P; Peukert K; Kiermaier A; Seoane J; Lukas J; et al.
Repression of p15(INK4b) expression by Myc through association with Miz-1
6130
#LCRNCRNode / Date / Journal / AuthorLCSGCS
2611347261 2001 NATURE CELL BIOLOGY 3 (4): 400-408
Seoane J; Pouponnot C; Staller P; Schader M; Eilers M; et al.
TGF beta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15(INK4b)
8120
2621671262 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98 (3): 992-999
Chen CR; Kang YB; Massague J
Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program
9106
26325103263 2001 TRANSCRIPTIONAL COREPRESSORS: MEDIATORS OF EUKARYOTIC GENE REPRESSION 254: 145-164
Wotton D; Massague J
Smad transcriptional corepressors in TGF beta family signaling
028
264963264 2002 BLOOD 99 (9): 3179-3187
Bollard CM; Rossig C; Calonge MJ; Huls MH; Wagner HJ; et al.
Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity
037
2652273265 2002 CELL 110 (1): 19-32
Chen CR; Kang YB; Siegel PM; Massague J
E2F4/5 and p107 as Smad cofactors linking the TGF beta receptor to c-myc repression
1280
266458266 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277 (5): 3176-3185
Lopez-Rovira T; Chalaux E; Massague J; Rosa JL; Ventura F
Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic protein-specific transcriptional activation of Id1 gene
352
26700267 2002 JOURNAL OF BONE AND MINERAL RESEARCH 17: S409-S409
Kakonen SM; Kang Y; Carreon MR; Niewolna M; Kakonen RS; et al.
Breast cancer cell lines selected from bone metastases have greater metastatic capacity and express increased vascular endothelial growth factor (VEGF), interleukin-11 (IL-11), and parathyroid hormone-related protein (PTHrP).
00
26800268 2002 JOURNAL OF NUCLEAR MEDICINE 43 (5): 69P-69P
Serganova I; Ponomarev I; Doubrovin M; Ageyeva L; Beresten T; et al.
Imaging TGF beta signal transduction pathway activity with PET.
01
269849269 2002 MOLECULAR CELL 10 (2): 271-282
Xu L; Kang YB; Col S; Massague J
Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGF beta signaling complexes in the cytoplasm and nucleus
647
270630270 2002 NATURE 419 (6908): 729-734
Seoane J; Le HV; Massague J
Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
8117
#LCRNCRNode / Date / Journal / AuthorLCSGCS
271112271 2002 NATURE MEDICINE 8 (10): 1076-1078
Blain SW; Massague J
Breast cancer banishes p27 from nucleus
023
272650272 2003 CANCER CELL 3 (6): 537-549
Kang YB; Siegel PM; Shu WP; Drobnjak M; Kakonen SM; et al.
A multigenic program mediating breast cancer metastasis to bone
6152
27331140273 2003 CELL 113 (6): 685-700
Shi YG; Massague J
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
10459
274832274 2003 GENES & DEVELOPMENT 17 (24): 2993-2997
Massague J
Integration of Smad and MAPK pathways: a link and a linker revisited
120
275328275 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (22): 20327-20331
Chai JJ; Wu JW; Yan N; Massague J; Pavletich NP; et al.
Features of a Smad3 MH1-DNA complex - Roles of water and zinc in DNA binding
16
276955276 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (37): 35444-35450
Siegel PM; Shu WP; Massague J
Mad upregulation and Id2 repression accompany transforming growth factor (TGF)-beta-mediated epithelial cell growth suppression
318
2771037277 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278 (43): 42569-42577
Xu L; Alarcon X; Col S; Massague J
Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import
212
278535278 2003 JOURNAL OF CELL BIOLOGY 162 (6): 1089-1098
Foletta VC; Lim MA; Soosairaiah J; Kelly AP; Stanley EG; et al.
Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1
239
27911279 2003 JOURNAL OF CELL BIOLOGY 163 (2): 421-421
Foletta VC; Lim MA; Soosairajah J; Kelly AP; Stanley EG; et al.
Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1 (vol 162, pg 1089, 2003)
01
2801357280 2003 MOLECULAR CELL 11 (4): 915-926
Kang YB; Chen CR; Massague J
A self-enabling TGF beta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells
862
#LCRNCRNode / Date / Journal / AuthorLCSGCS
28124173281 2003 NATURE REVIEWS CANCER 3 (11): 807-820
Siegel PM; Massague J
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
7128
28200282 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (4): 1464-1464
Cozzarelli NR; Halpern J; Allison JP; Andersen HC; Ausubel FM; et al.
Uncensored exchange of scientific results
06
283740283 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (14): 8430-8435
Siegel PM; Shu WP; Cardiff RD; Muller WJ; Massague J
Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis
244
2841483284 2004 CELL 117 (2): 211-223
Seoane J; Le HV; Shen LJ; Anderson SA; Massague J
Integration of Smad and Forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
374
285119285 2004 CELL 118 (3): 277-279
Kang YB; Massague J
Epithelial-mesenchymal transitions: Twist in development and metastasis
034
2861351286 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279 (22): 23759-23765
Calonge MJ; Seoane J; Massague J
Opposite smad and chicken ovalbumin upstream promoter transcription factor inputs in the regulation of the collagen VII gene promoter by transforming growth factor-beta
02
28700287 2004 JOURNAL OF BONE AND MINERAL RESEARCH 19 (9): 1561-1561
Massague J; Kang YB; Siegel PM; Shu WP; Minn A; et al.
Gene sets driving tissue-specific breast cancer metastasis
00
288219288 2004 JOURNAL OF CLINICAL INVESTIGATION 114 (12): 1691-1693
Gupta GP; Massague J
Platelets and metastasis revisited: a novel fatty link
03
289498289 2004 NATURE 432 (7015): 298-306
Massague J
G1 cell-cycle control and cancer
134
290944290 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (42): 15231-15236
Scandura JM; Boccuni P; Massague J; Nimer SD
Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation
17
#LCRNCRNode / Date / Journal / AuthorLCSGCS
29111291 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 (47): 16707-16707
Scandura JM; Boccuni P; Massague J; Nimer SD
Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation (Vol 101, pg 15231, 2004)
00
29200292 2005 BREAST CANCER RESEARCH AND TREATMENT 94: S3-S3
Massague J
Breast cancer metastasis genes and functions.
00
293745293 2005 CANCER CELL 8 (5): 369-380
Thomas DA; Massague J
TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
00
29448255294 2005 GENES & DEVELOPMENT 19 (23): 2783-2810
Massague J; Seoane J; Wotton D
Smad transcription factors
00
295353295 2005 JOURNAL OF BIOLOGICAL CHEMISTRY 280 (36): 32018-32025
Van Le H; Minn AJ; Massague J
Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells
00
296118296 2005 JOURNAL OF CLINICAL INVESTIGATION 115 (1): 44-55
Minn AJ; Kang YB; Serganova I; Gupta GP; Giri DD; et al.
Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors
217
297233297 2005 NATURE 436 (7050): 518-524
Minn AJ; Gupta GP; Siegel PM; Bos PD; Shu WP; et al.
Genes that mediate breast cancer metastasis to lung
15
29800298 2005 NEURO-ONCOLOGY 7 (3): 365-365
Lassman AB; Wang Q; Massague J; Holland EC
The transcription factor Foxg1 in gliomas
00
2991039299 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (39): 13909-13914
Kang YB; He W; Tulley S; Gupta GP; Serganova I; et al.
Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway
11

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