| Missing Links?: 77 Citation Matrix | Historiographs | Glossary HistCite Guide About |
Nodes: 972,
Authors: 1059,
Journals: 155,
Outer References: 9343,
Words: 1778
Yearly output |
Document Type |
Language |
Institution |
Institution with Subdivision |
Country
Collection span: 1970 - 2006
| View: Overview | Sorted by LCS. |
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| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
|---|---|---|---|---|---|
| 101 | 11 | 28 | 485 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263 (31): 15985-15992 ODOWD BF; HNATOWICH M; REGAN JW; LEADER WM; CARON MG; et al. SITE-DIRECTED MUTAGENESIS OF THE CYTOPLASMIC DOMAINS OF THE HUMAN BETA-2-ADRENERGIC RECEPTOR - LOCALIZATION OF REGIONS INVOLVED IN G-PROTEIN-RECEPTOR COUPLING | 21 | 335 |
| 102 | 8 | 33 | 656 1994 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91 (26): 12706-12710 KOCH WJ; HAWES BE; ALLEN LF; LEFKOWITZ RJ DIRECT EVIDENCE THAT G(I)-COUPLED RECEPTOR STIMULATION OF MITOGEN-ACTIVATED PROTEIN-KINASE IS MEDIATED BY G(BETA-GAMMA) ACTIVATION OF P21(RAS) | 21 | 337 |
| 103 | 10 | 27 | 730 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93 (18): 9954-9959 Rockman HA; Choi DJ; Rahman NU; Akhter SA; Lefkowitz RJ; et al. Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice | 21 | 95 |
| 104 | 10 | 43 | 751 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (49): 31051-31057 Lin FT; Krueger KM; Kendall HE; Daaka Y; Fredericks ZL; et al. Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1 | 21 | 95 |
| 105 | 9 | 39 | 822 1999 SCIENCE 286 (5449): 2495-2498 Bohn LM; Lefkowitz RJ; Gainetdinov RR; Peppel K; Caron MG; et al. Enhanced morphine analgesia in mice lacking beta-arrestin 2 | 21 | 120 |
| 106 | 16 | 60 | 836 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275 (15): 11312-11319 Miller WE; Maudsley S; Ahn S; Khan KD; Luttrell LM; et al. beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC - Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis | 21 | 93 |
| 107 | 6 | 21 | 182 1979 MOLECULAR PHARMACOLOGY 16 (1): 61-68 TSAI BS; LEFKOWITZ RJ AGONIST-SPECIFIC EFFECTS OF GUANINE-NUCLEOTIDES ON ALPHA-ADRENERGIC RECEPTORS IN HUMAN-PLATELETS | 20 | 192 |
| 108 | 11 | 28 | 545 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87 (8): 2896-2900 COTECCHIA S; EXUM S; CARON MG; LEFKOWITZ RJ REGIONS OF THE ALPHA-1-ADRENERGIC RECEPTOR INVOLVED IN COUPLING TO PHOSPHATIDYLINOSITOL HYDROLYSIS AND ENHANCED SENSITIVITY OF BIOLOGICAL FUNCTION | 20 | 262 |
| 109 | 4 | 34 | 585 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267 (3): 1422-1425 INGLESE J; GLICKMAN JF; LORENZ W; CARON MG; LEFKOWITZ RJ ISOPRENYLATION OF A PROTEIN-KINASE - REQUIREMENT OF FARNESYLATION ALPHA-CARBOXYL METHYLATION FOR FULL ENZYMATIC-ACTIVITY OF RHODOPSIN KINASE | 20 | 142 |
| 110 | 5 | 34 | 642 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269 (14): 10217-10220 TOUHARA K; INGLESE J; PITCHER JA; SHAW G; LEFKOWITZ RJ BINDING OF G-PROTEIN BETA-GAMMA-SUBUNITS TO PLECKSTRIN HOMOLOGY DOMAINS | 20 | 407 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 111 | 4 | 31 | 731 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93 (23): 12974-12979 Jaber M; Koch WJ; Rockman H; Smith B; Bond RA; et al. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function | 20 | 108 |
| 112 | 8 | 29 | 245 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256 (22): 1944-1950 LAVIN TN; HEALD SL; JEFFS PW; SHORR RGL; LEFKOWITZ RJ; et al. PHOTOAFFINITY-LABELING OF THE BETA-ADRENERGIC-RECEPTOR | 19 | 57 |
| 113 | 5 | 25 | 339 1984 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 121 (3): 973-979 SIBLEY DR; NAMBI P; PETERS JR; LEFKOWITZ RJ PHORBOL DIESTERS PROMOTE BETA-ADRENERGIC-RECEPTOR PHOSPHORYLATION AND ADENYLATE-CYCLASE DESENSITIZATION IN DUCK ERYTHROCYTES | 19 | 249 |
| 114 | 10 | 33 | 389 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260 (4): 2165-2171 NAMBI P; PETERS JR; SIBLEY DR; LEFKOWITZ RJ DESENSITIZATION OF THE TURKEY ERYTHROCYTE BETA-ADRENERGIC-RECEPTOR IN A CELL-FREE SYSTEM - EVIDENCE THAT MULTIPLE PROTEIN-KINASES CAN PHOSPHORYLATE AND DESENSITIZE THE RECEPTOR | 19 | 91 |
| 115 | 11 | 29 | 778 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (2): 685-688 Daaka Y; Luttrell LM; Ahn S; Della Rocca GJ; Ferguson SSG; et al. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase | 19 | 289 |
| 116 | 8 | 32 | 789 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95 (12): 7000-7005 Rockman HA; Chien KR; Choi DJ; Iaccarino G; Hunter JJ; et al. Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice | 19 | 199 |
| 117 | 2 | 25 | 873 2001 SCIENCE 294 (5545): 1307-1313 Shenoy SK; McDonald PH; Kohout TA; Lefkowitz RJ Regulation of receptor fate by ubiquitination of activated beta(2)- adrenergic receptor and beta-arrestin | 19 | 202 |
| 118 | 4 | 22 | 109 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252 (8): 2787-2789 WILLIAMS LT; LEFKOWITZ RJ; WATANABE AM; HATHAWAY DR; BESCH HR THYROID-HORMONE REGULATION OF BETA-ADRENERGIC-RECEPTOR NUMBER | 18 | 610 |
| 119 | 4 | 13 | 299 1983 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 110 (2): 504-511 BENOVIC JL; STILES GL; LEFKOWITZ RJ; CARON MG PHOTOAFFINITY-LABELING OF MAMMALIAN BETA-ADRENERGIC RECEPTORS - METAL-DEPENDENT PROTEOLYSIS EXPLAINS APPARENT HETEROGENEITY | 18 | 80 |
| 120 | 23 | 55 | 555 1991 BIOCHEMISTRY 30 (21): 5118-5125 ONORATO JJ; PALCZEWSKI K; REGAN JW; CARON MG; LEFKOWITZ RJ; et al. ROLE OF ACIDIC AMINO-ACIDS IN PEPTIDE-SUBSTRATES OF THE BETA-ADRENERGIC-RECEPTOR KINASE AND RHODOPSIN KINASE | 18 | 156 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 121 | 0 | 35 | 3 1970 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 65 (3): 745-& LEFKOWITZ RJ; ROTH J; PRICER W; PASTAN I ACTH RECEPTORS IN ADRENAL - SPECIFIC BINDING OF ACTH-1-125 AND ITS RELATION TO ADENYL CYCLASE | 17 | 310 |
| 122 | 7 | 35 | 209 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255 (5): 1854-1861 LIMBIRD LE; GILL DM; STADEL JM; HICKEY AR; LEFKOWITZ RJ LOSS OF BETA-ADRENERGIC RECEPTOR-GUANINE NUCLEOTIDE REGULATORY PROTEIN INTERACTIONS ACCOMPANIES DECLINE IN CATECHOLAMINE RESPONSIVENESS OF ADENYLATE-CYCLASE IN MATURING RAT ERYTHROCYTES | 17 | 130 |
| 123 | 8 | 17 | 283 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257 (16): 9242-9245 STADEL JM; NAMBI P; LAVIN TN; HEALD SL; CARON MG; et al. CATECHOLAMINE-INDUCED DESENSITIZATION OF TURKEY ERYTHROCYTE ADENYLATE-CYCLASE - STRUCTURAL ALTERATIONS IN THE BETA-ADRENERGIC-RECEPTOR REVEALED BY PHOTOAFFINITY-LABELING | 17 | 51 |
| 124 | 9 | 31 | 318 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258 (10): 6410-6414 STRULOVICI B; STADEL JM; LEFKOWITZ RJ FUNCTIONAL INTEGRITY OF DESENSITIZED BETA-ADRENERGIC RECEPTORS - INTERNALIZED RECEPTORS RECONSTITUTE CATECHOLAMINE-STIMULATED ADENYLATE-CYCLASE ACTIVITY | 17 | 68 |
| 125 | 45 | 281 | 371 1984 PHYSIOLOGICAL REVIEWS 64 (2): 661-743 STILES GL; CARON MG; LEFKOWITZ RJ BETA-ADRENERGIC RECEPTORS - BIOCHEMICAL-MECHANISMS OF PHYSIOLOGICAL REGULATION | 17 | 693 |
| 126 | 18 | 43 | 589 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267 (12): 8558-8564 LOHSE MJ; ANDEXINGER S; PITCHER J; TRUKAWINSKI S; CODINA J; et al. RECEPTOR-SPECIFIC DESENSITIZATION WITH PURIFIED PROTEINS - KINASE DEPENDENCE AND RECEPTOR SPECIFICITY OF BETA-ARRESTIN AND ARRESTIN IN THE BETA-2-ADRENERGIC RECEPTOR AND RHODOPSIN SYSTEMS | 17 | 186 |
| 127 | 19 | 43 | 608 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268 (5): 3201-3208 PIPPIG S; ANDEXINGER S; DANIEL K; PUZICHA M; CARON MG; et al. OVEREXPRESSION OF BETA-ARRESTIN AND BETA-ADRENERGIC-RECEPTOR KINASE AUGMENT DESENSITIZATION OF BETA(2)-ADRENERGIC RECEPTORS | 17 | 154 |
| 128 | 7 | 22 | 762 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94 (22): 12100-12105 Akhter SA; Skaer CA; Kypson AP; McDonald PH; Peppel KC; et al. Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer | 17 | 107 |
| 129 | 17 | 47 | 854 2001 CURRENT OPINION IN CELL BIOLOGY 13 (2): 139-145 Miller WE; Lefkowitz RJ Expanding roles for beta-arrestins as scaffolds and adapters in GPCR signaling and trafficking | 17 | 143 |
| 130 | 11 | 34 | 880 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277 (11): 9429-9436 Tohgo AK; Pierce KL; Choy EW; Lefkowitz RJ; Luttrell LM beta-arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation | 17 | 77 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 131 | 27 | 77 | 884 2002 JOURNAL OF CELL SCIENCE 115 (3): 455-465 Luttrell LM; Lefkowitz RJ The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals | 17 | 195 |
| 132 | 1 | 15 | 92 1976 SCIENCE 192 (4241): 791-793 WILLIAMS LT; LEFKOWITZ RJ ALPHA-ADRENERGIC RECEPTOR IDENTIFICATION BY [DIHYDROERGOCRYPTINE-H-3] BINDING | 16 | 115 |
| 133 | 7 | 20 | 431 1986 NATURE 321 (6073): 869-872 BENOVIC JL; MAYOR F; SOMERS RL; CARON MG; LEFKOWITZ RJ LIGHT-DEPENDENT PHOSPHORYLATION OF RHODOPSIN BY BETA-ADRENERGIC-RECEPTOR KINASE | 16 | 117 |
| 134 | 10 | 24 | 453 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262 (32): 15796-15802 KOBILKA BK; MACGREGOR C; DANIEL K; KOBILKA TS; CARON MG; et al. FUNCTIONAL-ACTIVITY AND REGULATION OF HUMAN BETA-2-ADRENERGIC RECEPTORS EXPRESSED IN XENOPUS OOCYTES | 16 | 104 |
| 135 | 7 | 38 | 490 1988 NATURE 335 (6188): 358-360 FARGIN A; RAYMOND JR; LOHSE MJ; KOBILKA BK; CARON MG; et al. THE GENOMIC CLONE G-21 WHICH RESEMBLES A BETA-ADRENERGIC-RECEPTOR SEQUENCE ENCODES THE 5-HT1A RECEPTOR | 16 | 475 |
| 136 | 6 | 27 | 690 1995 NATURE 376 (6543): 781-784 VANBIESEN T; HAWES BE; LUTTRELL DK; KRUEGER KM; TOUHARA K; et al. RECEPTOR-TYROSINE-KINASE-MEDIATED AND G-BETA-GAMMA-MEDIATED MAP KINASE ACTIVATION BY A COMMON SIGNALING PATHWAY | 16 | 347 |
| 137 | 18 | 25 | 729 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93 (15): 7649-7654 Oppermann M; DiversePierluissi H; Drazner MH; Dyer SL; Freedman NJ; et al. Monoclonal antibodies reveal receptor specificity G-protein-coupled receptor kinases | 16 | 60 |
| 138 | 10 | 26 | 781 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273 (29): 18180-18184 Rockman HA; Choi DJ; Akhter SA; Jaber M; Giros B; et al. Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice | 16 | 63 |
| 139 | 4 | 30 | 844 2000 NATURE 408 (6813): 720-723 Bohn LM; Gainetdinov RR; Lin FT; Lefkowitz RJ; Caron MG mu-Opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence | 16 | 165 |
| 140 | 14 | 28 | 915 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100 (4): 1740-1744 Ahn S; Nelson CD; Garrison TR; Miller WE; Lefkowitz RJ Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference | 16 | 44 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 141 | 7 | 22 | 108 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252 (2): 799-802 LIMBIRD LE; LEFKOWITZ RJ RESOLUTION OF BETA-ADRENERGIC-RECEPTOR BINDING AND ADENYLATE-CYCLASE ACTIVITY BY GEL EXCLUSION CHROMATOGRAPHY | 15 | 137 |
| 142 | 11 | 32 | 110 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252 (15): 5295-5303 LEFKOWITZ RJ; MULLIKIN D; WOOD CL; GORE TB; MUKHERJEE C REGULATION OF PROSTAGLANDIN RECEPTORS BY PROSTAGLANDINS AND GUANINE NUCLEOTIDES IN FROG ERYTHROCYTES | 15 | 187 |
| 143 | 14 | 49 | 169 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254 (8): 2677-2683 LIMBIRD LE; HICKEY AR; LEFKOWITZ RJ UNIQUE UNCOUPLING OF THE FROG ERYTHROCYTE ADENYLATE-CYCLASE SYSTEM BY MANGANESE - LOSS OF HORMONE AND GUANINE NUCLEOTIDE-SENSITIVE ENZYME-ACTIVITIES WITHOUT LOSS OF NUCLEOTIDE-SENSITIVE, HIGH-AFFINITY AGONIST BINDING | 15 | 145 |
| 144 | 30 | 156 | 186 1980 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 20: 581-608 HOFFMAN BB; LEFKOWITZ RJ RADIOLIGAND BINDING-STUDIES OF ADRENERGIC-RECEPTORS - NEW INSIGHTS INTO MOLECULAR AND PHYSIOLOGICAL REGULATION | 15 | 306 |
| 145 | 29 | 163 | 260 1982 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY 53: 1-43 STADEL JM; DELEAN A; LEFKOWITZ RJ MOLECULAR MECHANISMS OF COUPLING IN HORMONE RECEPTOR-ADENYLATE CYCLASE SYSTEMS | 15 | 126 |
| 146 | 9 | 24 | 332 1983 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 80 (16): 4899-4903 CERIONE RA; STRULOVICI B; BENOVIC JL; STRADER CD; CARON MG; et al. RECONSTITUTION OF BETA-ADRENERGIC RECEPTORS IN LIPID VESICLES - AFFINITY-CHROMATOGRAPHY PURIFIED RECEPTORS CONFER CATECHOLAMINE RESPONSIVENESS ON A HETEROLOGOUS ADENYLATE-CYCLASE SYSTEM | 15 | 37 |
| 147 | 10 | 28 | 359 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259 (4): 2579-2587 LEEBLUNDBERG LMF; DICKINSON KEJ; HEALD SL; WIKBERG JES; HAGEN PO; et al. PHOTOAFFINITY-LABELING OF MAMMALIAN ALPHA-1-ADRENERGIC RECEPTORS - IDENTIFICATION OF THE LIGAND-BINDING SUBUNIT WITH A HIGH-AFFINITY RADIOIODINATED PROBE | 15 | 91 |
| 148 | 4 | 23 | 365 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259 (16): 9979-9982 CERIONE RA; SIBLEY DR; CODINA J; BENOVIC JL; WINSLOW J; et al. RECONSTITUTION OF A HORMONE-SENSITIVE ADENYLATE-CYCLASE SYSTEM - THE PURE BETA-ADRENERGIC-RECEPTOR AND GUANINE-NUCLEOTIDE REGULATORY PROTEIN CONFER HORMONE RESPONSIVENESS ON THE RESOLVED CATALYTIC UNIT | 15 | 92 |
| 149 | 7 | 45 | 400 1985 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82 (17): 5651-5655 LEEBLUNDBERG LMF; COTECCHIA S; LOMASNEY JW; DEBERNARDIS JF; LEFKOWITZ RJ; et al. PHORBOL ESTERS PROMOTE ALPHA-1-ADRENERGIC RECEPTOR PHOSPHORYLATION AND RECEPTOR UNCOUPLING FROM INOSITOL PHOSPHOLIPID-METABOLISM | 15 | 392 |
| 150 | 7 | 28 | 423 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261 (8): 3894-3900 REGAN JW; NAKATA H; DEMARINIS RM; CARON MG; LEFKOWITZ RJ PURIFICATION AND CHARACTERIZATION OF THE HUMAN-PLATELET ALPHA-2-ADRENERGIC RECEPTOR | 15 | 98 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 151 | 10 | 30 | 488 1988 MOLECULAR PHARMACOLOGY 33 (2): 133-139 BOUVIER M; HNATOWICH M; COLLINS S; KOBILKA BK; DEBLASI A; et al. EXPRESSION OF A HUMAN CDNA-ENCODING THE BETA-2-ADRENERGIC RECEPTOR IN CHINESE-HAMSTER FIBROBLASTS (CHW) - FUNCTIONALITY AND REGULATION OF THE EXPRESSED RECEPTORS | 15 | 87 |
| 152 | 20 | 49 | 496 1989 ANNUAL REVIEW OF NEUROSCIENCE 12: 67-83 ODOWD BF; LEFKOWITZ RJ; CARON MG STRUCTURE OF THE ADRENERGIC AND RELATED RECEPTORS | 15 | 295 |
| 153 | 11 | 28 | 501 1989 BIOCHEMISTRY 28 (11): 4543-4547 KWATRA MM; BENOVIC JL; CARON MG; LEFKOWITZ RJ; HOSEY MM PHOSPHORYLATION OF CHICK HEART MUSCARINIC CHOLINERGIC RECEPTORS BY THE BETA-ADRENERGIC-RECEPTOR KINASE | 15 | 139 |
| 154 | 15 | 31 | 508 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264 (13): 7564-7569 ODOWD BF; HNATOWICH M; CARON MG; LEFKOWITZ RJ; BOUVIER M PALMITOYLATION OF THE HUMAN BETA-2-ADRENERGIC RECEPTOR - MUTATION OF CYS-341 IN THE CARBOXYL TAIL LEADS TO AN UNCOUPLED NONPALYMITOYLATED FORM OF THE RECEPTOR | 15 | 498 |
| 155 | 3 | 50 | 680 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270 (29): 17148-17153 HAWES BE; VANBIESEN T; KOCH WJ; LUTTRELL LM; LEFKOWITZ RJ DISTINCT PATHWAYS OF G(I)-MEDIATED AND G(Q)-MEDIATED MITOGEN-ACTIVATED PROTEIN-KINASE ACTIVATION | 15 | 360 |
| 156 | 11 | 38 | 714 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (22): 13266-13272 Oppermann M; Freedman NJ; Alexander RW; Lefkowitz RJ Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C | 15 | 152 |
| 157 | 12 | 31 | 744 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (1): 5-8 Krueger KM; Daaka Y; Pitcher JA; Lefkowitz RJ The role of sequestration in G protein-coupled receptor resensitization - Regulation of beta(2)-adrenergic receptor dephosphorylation by vesicular acidification | 15 | 207 |
| 158 | 8 | 25 | 750 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (41): 25425-25428 Peppel K; Boekhoff I; McDonald P; Breer H; Caron MG; et al. G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization | 15 | 56 |
| 159 | 13 | 39 | 817 1999 NEURON 24 (4): 1029-1036 Gainetdinov RR; Bohn LM; Walker JKL; Laporte SA; Macrae AD; et al. Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice | 15 | 46 |
| 160 | 10 | 31 | 425 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261 (17): 7710-7716 LOMASNEY JW; LEEBLUNDBERG LMF; COTECCHIA S; REGAN JW; DEBERNARDIS JF; et al. MAMMALIAN-ALPHA-1-ADRENERGIC RECEPTOR - PURIFICATION AND CHARACTERIZATION OF THE NATIVE RECEPTOR LIGAND-BINDING SUBUNIT | 14 | 77 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 161 | 13 | 39 | 587 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267 (3): 1633-1639 COTECCHIA S; OSTROWSKI J; KJELSBERG MA; CARON MG; LEFKOWITZ RJ DISCRETE AMINO-ACID-SEQUENCES OF THE ALPHA-1-ADRENERGIC RECEPTOR DETERMINE THE SELECTIVITY OF COUPLING TO PHOSPHATIDYLINOSITOL HYDROLYSIS | 14 | 127 |
| 162 | 11 | 31 | 607 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268 (1): 337-341 YU SS; LEFKOWITZ RJ; HAUSDORFF WP BETA-ADRENERGIC-RECEPTOR SEQUESTRATION - A POTENTIAL MECHANISM OF RECEPTOR RESENSITIZATION | 14 | 320 |
| 163 | 9 | 33 | 623 1993 SCIENCE 259 (5096): 825-829 DAWSON TM; ARRIZA JL; JAWORSKY DE; BORISY FF; ATTRAMADAL H; et al. BETA-ADRENERGIC-RECEPTOR KINASE-2 AND BETA-ARRESTIN-2 AS MEDIATORS OF ODORANT-INDUCED DESENSITIZATION | 14 | 126 |
| 164 | 12 | 32 | 635 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269 (1): 37-40 BOEKHOFF I; INGLESE J; SCHLEICHER S; KOCH WJ; LEFKOWITZ RJ; et al. OLFACTORY DESENSITIZATION REQUIRES MEMBRANE TARGETING OF RECEPTOR KINASE MEDIATED BY BETA-GAMMA-SUBUNITS OF HETEROTRIMERIC G-PROTEINS | 14 | 71 |
| 165 | 8 | 31 | 644 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269 (45): 27791-27794 STOFFEL RH; RANDALL RR; PREMONT RT; LEFKOWITZ RJ; INGLESE J PALMITOYLATION OF G-PROTEIN-COUPLED RECEPTOR KINASE, GRK6 - LIPID MODIFICATION DIVERSITY IN THE GRK FAMILY | 14 | 69 |
| 166 | 7 | 57 | 716 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271 (32): 19443-19450 Luttrell LM; Hawes BE; vanBiesen T; Luttrell DK; Lansing TJ; et al. Role of c-Src tyrosine kinase in G protein-coupled receptor-and G beta gamma subunit-mediated activation of mitogen-activated protein kinases | 14 | 360 |
| 167 | 4 | 30 | 787 1998 NATURE 392 (6676): 626-630 Hall RA; Premont RT; Chow CW; Blitzer JT; Pitcher JA; et al. The beta(2)-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange | 14 | 291 |
| 168 | 10 | 27 | 810 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274 (23): 15971-15974 Lin FT; Miller WE; Luttrell LM; Lefkowitz RJ Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinases | 14 | 46 |
| 169 | 16 | 39 | 891 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 (11): 7478-7483 Fong AM; Premont RT; Richardson RM; Yu YRA; Lefkowitz RJ; et al. Defective lymphocyte chemotaxis in beta-arresting2-and GRK6-deficient mice | 14 | 48 |
| 170 | 30 | 174 | 892 2002 PROGRESS IN NEUROBIOLOGY 66 (2): 61-79 Claing A; Laporte SA; Caron MG; Lefkowitz RJ Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins | 14 | 151 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 171 | 29 | 70 | 894 2002 TRENDS IN CELL BIOLOGY 12 (3): 130-138 Perry SJ; Lefkowitz RJ Arresting developments in heptahelical receptor signaling and regulation | 14 | 88 |
| 172 | 8 | 21 | 73 1976 ENDOCRINOLOGY 99 (2): 347-357 MUKHERJEE C; CARON MG; LEFKOWITZ RJ REGULATION OF ADENYLATE-CYCLASE COUPLED BETA-ADRENERGIC RECEPTORS BY BETA-ADRENERGIC CATECHOLAMINES | 13 | 114 |
| 173 | 7 | 27 | 223 1980 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 77 (8): 4569-4573 HOFFMAN BB; MICHEL T; KILPATRICK DM; LEFKOWITZ RJ; TOLBERT MEM; et al. AGONIST VERSUS ANTAGONIST BINDING TO ALPHA-ADRENERGIC RECEPTORS | 13 | 155 |
| 174 | 4 | 19 | 388 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260 (3): 1493-1500 CERIONE RA; STANISZEWSKI C; BENOVIC JL; LEFKOWITZ RJ; CARON MG; et al. SPECIFICITY OF THE FUNCTIONAL INTERACTIONS OF THE BETA-ADRENERGIC-RECEPTOR AND RHODOPSIN WITH GUANINE-NUCLEOTIDE REGULATORY PROTEINS RECONSTITUTED IN PHOSPHOLIPID-VESICLES | 13 | 201 |
| 175 | 11 | 29 | 472 1988 BIOCHEMISTRY 27 (6): 1813-1817 DOHLMAN HG; CARON MG; STRADER CD; AMLAIKY N; LEFKOWITZ RJ IDENTIFICATION AND SEQUENCE OF A BINDING-SITE PEPTIDE OF THE BETA-2-ADRENERGIC RECEPTOR | 13 | 117 |
| 176 | 13 | 42 | 511 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264 (28): 16786-16792 BOUVIER M; COLLINS S; ODOWD BF; CAMPBELL PT; DEBLASI A; et al. 2 DISTINCT PATHWAYS FOR CAMP-MEDIATED DOWN-REGULATION OF THE BETA-2-ADRENERGIC RECEPTOR - PHOSPHORYLATION OF THE RECEPTOR AND REGULATION OF ITS MESSENGER-RNA LEVEL | 13 | 238 |
| 177 | 14 | 38 | 538 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265 (14): 8183-8189 SCHWINN DA; LOMASNEY JW; LORENZ W; SZKLUT PJ; FREMEAU RT; et al. MOLECULAR-CLONING AND EXPRESSION OF THE CDNA FOR A NOVEL ALPHA-1-ADRENERGIC RECEPTOR SUBTYPE | 13 | 416 |
| 178 | 8 | 17 | 572 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88 (14): 6201-6204 ROTH NS; CAMPBELL PT; CARON MG; LEFKOWITZ RJ; LOHSE MJ COMPARATIVE RATES OF DESENSITIZATION OF BETA-ADRENERGIC RECEPTORS BY THE BETA-ADRENERGIC-RECEPTOR KINASE AND THE CYCLIC AMP-DEPENDENT PROTEIN-KINASE | 13 | 112 |
| 179 | 8 | 26 | 620 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90 (4): 1420-1424 SCHLEICHER S; BOEKHOFF I; ARRIZA J; LEFKOWITZ RJ; BREER H A BETA-ADRENERGIC-RECEPTOR KINASE-LIKE ENZYME IS INVOLVED IN OLFACTORY SIGNAL TERMINATION | 13 | 104 |
| 180 | 3 | 29 | 655 1994 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91 (21): 10109-10113 MILANO CA; DOLBER PC; ROCKMAN HA; BOND RA; VENABLE ME; et al. MYOCARDIAL EXPRESSION OF A CONSTITUTIVELY ACTIVE ALPHA(1B)-ADRENERGIC RECEPTOR IN TRANSGENIC MICE INDUCES CARDIAC-HYPERTROPHY | 13 | 231 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 181 | 14 | 39 | 679 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270 (28): 17000-17005 TOUHARA K; KOCH WJ; HAWES BE; LEFKOWITZ RJ MUTATIONAL ANALYSIS OF THE PLECKSTRIN HOMOLOGY DOMAIN OF THE BETA-ADRENERGIC-RECEPTOR KINASE - DIFFERENTIAL-EFFECTS ON G(BETA-GAMMA) AND PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE BINDING | 13 | 83 |
| 182 | 24 | 269 | 708 1996 ENDOCRINE REVIEWS 17 (6): 698-714 vanBiesen T; Luttrell LM; Hawes BE; Lefkowitz RJ Mitogenic signaling via G protein-coupled receptors | 13 | 317 |
| 183 | 5 | 48 | 746 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (7): 4637-4644 Luttrell LM; DellaRocca GJ; vanBiesen T; Luttrell DK; Lefkowitz RJ G beta gamma subunits Src-dependent phosphorylation of the epidermal growth factor receptor - A scaffold for G protein-coupled receptor-mediated Ras activation | 13 | 313 |
| 184 | 4 | 14 | 14 1972 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 69 (10): 2828-& LEFKOWITZ RJ; HABER E; OHARA D IDENTIFICATION OF CARDIAC BETA-ADRENERGIC RECEPTOR PROTEIN - SOLUBILIZATION AND PURIFICATION BY AFFINITY CHROMATOGRAPHY | 12 | 107 |
| 185 | 3 | 24 | 56 1975 JOURNAL OF BIOLOGICAL CHEMISTRY 250 (12): 4418-4422 LEFKOWITZ RJ; CARON MG CHARACTERISTICS OF 5'-GUANYLYL IMIDODIPHOSPHATE-ACTIVATED ADENYLATE CYCLASE | 12 | 70 |
| 186 | 24 | 153 | 66 1976 BIOCHIMICA ET BIOPHYSICA ACTA 457 (1): 1-39 LEFKOWITZ RJ; LIMBIRD LE; MUKHERJEE C; CARON MG BETA-ADRENERGIC-RECEPTOR AND ADENYLATE-CYCLASE | 12 | 152 |
| 187 | 7 | 22 | 90 1976 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73 (5): 1494-1498 MUKHERJEE C; LEFKOWITZ RJ DESENSITIZATION OF BETA-ADRENERGIC RECEPTORS BY BETA-ADRENERGIC AGONISTS IN A CELL-FREE SYSTEM - RESENSITIZATION BY GUANOSINE 5'- (BETA,GAMMA-IMINO) TRIPHOSPHATE AND OTHER PURINE NUCLEOTIDES | 12 | 149 |
| 188 | 14 | 31 | 181 1979 MOLECULAR PHARMACOLOGY 16 (1): 10-20 WESSELS MR; MULLIKIN D; LEFKOWITZ RJ SELECTIVE ALTERATION IN HIGH-AFFINITY AGONIST BINDING - MECHANISM OF BETA-ADRENERGIC-RECEPTOR DESENSITIZATION | 12 | 104 |
| 189 | 13 | 35 | 298 1983 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 224 (1): 142-151 BRIGGS MM; STADEL JM; IYENGAR R; LEFKOWITZ RJ FUNCTIONAL MODIFICATION OF THE GUANINE-NUCLEOTIDE REGULATORY PROTEIN AFTER DESENSITIZATION OF TURKEY ERYTHROCYTES BY CATECHOLAMINES | 12 | 43 |
| 190 | 9 | 40 | 362 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259 (12): 7864-7869 REGAN JW; DEMARINIS RM; CARON MG; LEFKOWITZ RJ IDENTIFICATION OF THE SUBUNIT-BINDING SITE OF ALPHA-2-ADRENERGIC RECEPTORS USING [PHENOXYBENZAMINE-H-3 | 12 | 44 |
| # | LCR | NCR | Node / Date / Journal / Author | LCS | GCS |
| 191 | 5 | 28 | 507 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264 (12): 6707-6710 BENOVIC JL; STONE WC; CARON MG; LEFKOWITZ RJ INHIBITION OF THE BETA-ADRENERGIC-RECEPTOR KINASE BY POLYANIONS | 12 | 65 |
| 192 | 8 | 39 | 535 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265 (1): 63-69 COTECCHIA S; KOBILKA BK; DANIEL KW; NOLAN RD; LAPETINA EY; et al. MULTIPLE 2ND MESSENGER PATHWAYS OF ALPHA-ADRENERGIC RECEPTOR SUBTYPES EXPRESSED IN EUKARYOTIC CELLS | 12 | 254 |
| 193 | 10 | 34 | 547 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87 (13): 5094-5098 LOMASNEY JW; LORENZ W; ALLEN LF; KING K; REGAN JW; et al. EXPANSION OF THE ALPHA-2-ADRENERGIC RECEPTOR FAMILY - CLONING AND CHARACTERIZATION OF A HUMAN ALPHA-2-ADRENERGIC RECEPTOR SUBTYPE, THE GENE FOR WHICH IS LOCATED ON CHROMOSOME-2 | 12 | 283 |
| 194 | 11 | 34 | 636 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269 (2): 1125-1130 ISHII K; CHEN J; ISHII M; KOCH WJ; FREEDMAN NJ; et al. INHIBITION OF THROMBIN RECEPTOR SIGNALING BY A G-PROTEIN COUPLED RECEPTOR KINASE - FUNCTIONAL SPECIFICITY AMONG G-PROTEIN COUPLED RECEPTOR KINASES | 12 | 179 |
| 195 | 11 | 38 | 654 1994 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91 (9): 3637-3641 INGLESE J; LUTTRELL LM; INIGUEZLLUHI JA; TOUHARA K; KOCH WJ; et al. FUNCTIONALLY ACTIVE TARGETING DOMAIN OF THE BETA-ADRENERGIC-RECEPTOR KINASE - AN INHIBITOR OF G-BETA-GAMMA-MEDIATED STIMULATION OF TYPE-II ADENYLYL-CYCLASE | 12 | 61 |
| 196 | 6 | 29 | 689 1995 NATURE 374 (6519): 272-276 BOND RA; LEFF P; JOHNSON TD; MILANO CA; ROCKMAN HA; et al. PHYSIOLOGICAL-EFFECTS OF INVERSE AGONISTS IN TRANSGENIC MICE WITH MYOCARDIAL OVEREXPRESSION OF THE BETA(2)-ADRENOCEPTOR | 12 | 319 |
| 197 | 17 | 52 | 747 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272 (28): 17734-17743 Freedman NJ; Ament AS; Oppermann M; Stoffel RH; Exum ST; et al. Phosphorylation and desensitization of human endothelin A and B receptors - Evidence for G protein-coupled receptor kinase specificity | 12 | 106 |
| 198 | 9 | 35 | 806 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274 (3): 1185-1188 Ahn S; Maudsley S; Luttrell LM; Lefkowitz RJ; Daaka Y Src-mediated tyrosine phosphorylation of dynamin is required for beta(2)-adrenergic receptor internalization and mitogen-activated protein kinase signaling | 12 | 133 |
| 199 | 11 | 47 | 835 2000 JOURNAL OF BIOLOGICAL CHEMISTRY 275 (13): 9572-9580 Maudsley S; Pierce KL; Zamah AM; Miller WE; Ahn S; et al. The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor | 12 | 185 |
| 200 | 12 | 51 | 867 2001 ONCOGENE 20 (13): 1532-1539 Pierce KL; Luttrell LM; Lefkowitz RJ New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades | 12 | 171 |
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